LOCUS       c00007_gnlPro..        15977 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MPMJAAML_7.
ACCESSION   c00007_gnlPro..
VERSION     c00007_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 15:30:10
            Original ID  :: gnl|Prokka|MPMJAAML_7
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15977
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15977
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2764:5977]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2765..5977
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..15977
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15977
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(140..745)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_1"
                     /sec_met_domain="LysR_substrate (E-value: 9e-19, bitscore:
                     58.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDAVIKDFILLAKKVY"
     CDS             complement(748..909)
                     /locus_tag="ctg7_2"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMFNKYQIRKDKKQISDE
                     GHAPLDEN"
     CDS             complement(925..2091)
                     /locus_tag="ctg7_3"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMPRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLACMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             complement(2212..2748)
                     /locus_tag="ctg7_4"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNNGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             complement(2765..3106)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_5"
                     /sec_met_domain="AA_kinase (E-value: 3.3e-19, bitscore:
                     60.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             complement(3275..3697)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_6"
                     /sec_met_domain="AA_kinase (E-value: 4.4e-13, bitscore:
                     39.9, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVAFGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNLAMPLDTVVSMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKLIGPFYTFNEMQR"
     CDS             complement(3892..4500)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_7"
                     /sec_met_domain="OTCace (E-value: 1.9e-37, bitscore: 119.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1.3e-24, bitscore:
                     77.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDDIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKVLTLAYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMNMMYMTGTPDDQLIFMHCLPAFHD"
     CDS             complement(4599..4736)
                     /locus_tag="ctg7_8"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSLLKCKDYTPTELNYLIDFALHLKELKKIFRMNI
                     "
     CDS             complement(4748..5020)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_9"
                     /sec_met_domain="Amidinotransf (E-value: 7.6e-31, bitscore:
                     97.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLKNYLHLSEIDLIPTGGGDAIAAPREQWNDGSNTLAIAPGEVVT
                     YDRNYVSNDLLRKHGILVHEIHSSELSRGRGGPRCMSCPLVREDL"
     CDS             complement(5250..5660)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_10"
                     /sec_met_domain="Amidinotransf (E-value: 2.6e-28, bitscore:
                     89.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEMQNATPSLADLAENPDYPFYL
                     DPMPNVYFTRDQQATIGNGMTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWCDRY
                     THGRLEGGDELILNNHVFSNRYFSKNFRCRNH"
     CDS             complement(5792..5977)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_11"
                     /sec_met_domain="Amidinotransf (E-value: 1.9e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             complement(6050..6904)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     72.5; E-value: 6.7e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg7_12"
                     /sec_met_domain="LysR_substrate (E-value: 2.1e-28,
                     bitscore: 89.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.5e-23, bitscore: 72.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAKEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKFKDKTGLRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKYSNWITHLQLVRRKDQKVTPLMKRIIDS
                     LSR"
     CDS             7033..9306
                     /locus_tag="ctg7_13"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSNLSDLPDKDVLALVGSATDKRNAGII
                     DIAIDEYLKENDIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(9375..9872)
                     /locus_tag="ctg7_14"
                     /transl_table=11
                     /translation="MRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTRN
                     ATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVVN
                     RIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVT
                     NY"
     CDS             10134..10700
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_15"
                     /sec_met_domain="PLDc_2 (E-value: 2e-09, bitscore: 28.1,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLTVLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQ
                     RDMLKEHDLLPEKERLPRVRMLSELNLNNDDAILTFDNQVKVFISGPELFDQMITDIKN
                     AKKSVSLELYTFYSNQLGHRVLKALEEAAANGAKVRVIYDTSGSRGTKPSFFDHLRAAK
                     LSHLFPLQKSTGLLPHDSITTYIEN"
     CDS             10847..11494
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_16"
                     /sec_met_domain="PLDc_2 (E-value: 6.9e-28, bitscore: 87.8,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDWNTSIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQLFPQDL
                     IINITASDEAEGIIAGAKKYIYIQTPYLIPEESILEALIIAANSGIDVRIMVPCMPDHP
                     FVYRATEYYAKYLVAHGVKVYKYNDGFIHAKTMVSGSNISSVGSANQDFRSYTLNFEVN
                     SFNYNPALTQELKKIFEKDLDKCTLLTNDYFAQQSSWLKFKQYFSRLLSPIF"
     CDS             11622..12416
                     /locus_tag="ctg7_17"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSKGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             12432..13361
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_18"
                     /sec_met_domain="PALP (E-value: 6e-69, bitscore: 223.2,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIYNSVTELIGNTPLLKLNRVVPDDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKDYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEELVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKNGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGDRYLSTALFNA"
     CDS             complement(13505..14032)
                     /locus_tag="ctg7_19"
                     /transl_table=11
                     /translation="MAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRIATHELAEY
                     AKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLE
                     MHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKGREKLPD
                     VDIYSLVQYHGA"
ORIGIN
        1 accaatcata cgagaaagga actccttttt ctaatatttt aagaaattaa tttaaggaat
       61 cattcatcct tacacaaact attttacagt ctccacaaac tattttacag tctccagtat
      121 tttgctgttc caagatagat taatatactt ttttagctaa caaaataaaa tctttaatta
      181 ctgcatcttc attggtataa aaagctgcaa tcttttgcca catttgttgt ccattagaca
      241 ataaaaacaa tcgttgtaaa gtatcattac taattaaact ggcggttgct tcattcatta
      301 aaaaatatcc tgatccagaa gctactaaca atgctgcctc ttctacggaa tttgaagcaa
      361 tgaatgggct tctaatctga taaatatctt taaataaatg gagttctgca gcctcttctt
      421 caggcttagc tacaataaaa caggttaaat cagctagatc atctttattg atcatctgaa
      481 caccgctagg ataactaccc ttttgcaaaa tagccattac tgcttcctga cctaagattt
      541 ctttcttaaa atcgagctga tcatcgcgca aatcactaat cgctaaatca acttcatttt
      601 tggctaattt atcaaaagct tcatcgtgtc ccattccaat taattcaatt tctacatcag
      661 aatgtttttg cttaaattgg tctacaattc gatctaattg tcttctacca agttggttaa
      721 agtatgctat tctcaatttt ttcatagtta attttcatcc aatggggcat gaccttcatc
      781 tgatatttgt tttttatctt ttctaatttg atatttgttg aacataatca atagcgaaat
      841 aaccacattt attccactaa ctaccacgct taaaaatttt agtaatctaa ctttcttttg
      901 cttactcatt ttggatacct tcttctaaaa ataatcataa aatgagactt taccttttac
      961 aaagtccaac tttttaattc gataatctgt gatcaaacca agtttaattg cggattccat
     1021 agttaaacgt cctaataaga tttgagtcca tgttgtaatt ggaccagaga aatcaactag
     1081 ttcatcttct tttcgttcac acttaacttg gtgatcataa ttagttaatt gccaaacgcc
     1141 aatattccat ggacactgat catcataatt aacttcgatg ttaaaagtac cctcttgcaa
     1201 tgggcgcatg catgccaaga ctttttggaa atcaataatt ctactcatca tatatggatg
     1261 aagttgaata tccaattcat tttgctctgg aaaaagttca gccaataaag acttctcagg
     1321 caatgtcata caaaactctt taattgaccc tatatgagct gccataaagc ctaatatgct
     1381 taataatcct tgaggcgtaa ttgaatataa ttcatcagcc ataaaacagt tatcaattat
     1441 gcgataaatc aagtagctca tcggccgacc agcttcatcg aagtaaacag caatctctcg
     1501 atgatgataa taatcatcta atctattcca ccaccaagct tctctgatga tcgtatttct
     1561 ttcatcgtca gtatgcaact gacgttcata taattgaatc acaccatttt gaacaatcaa
     1621 atcattccat tttccacgaa ttatcttacc tttgcgtggt aatctgaaag aagcaagtgc
     1681 agcccccgaa aagcgatatt ctttttggta aatactattg ctaaaaccat aatgacgata
     1741 aaatttttct gaaaatggag ctagatttgc aactgggatt ttttgatcat gcaaatcaaa
     1801 aagaatttct ttcattaatt tagatatatg tccacgtcct ctgtattcag gatatgatgc
     1861 cacataacca atacctgcca gtggaacatg atgaccaaat atctcagctt taaacttatt
     1921 gaccatcata taactggtca atttttcttg atcaaaatat ccatatccat cactatgatc
     1981 atatcggggc ataaagttac tatctgtagt caaatcagaa tcttttaaaa aagcatattc
     2041 aatcaatgaa gcaatttgtt ttaaattgtc ttggtttttc tttaatttca tagttttcct
     2101 tacaatatat attcataact ttacttatat tttagaacat tttatgtatt tttcgttagc
     2161 tttttttaag atttaaatga aaaaacggga tgattagcct cccatcccgt tttaattatt
     2221 tacatacttc gcatataaac tagaaatgta tctttgcatc tcttctactg agtgtcgccg
     2281 tgatcgagca cactctttag cagggcgatt gcataaatag cagcggcgac tagagtattc
     2341 aagctcttgg cgtgaaagtg cagttttccc tttaattaat acatcggcat caaataatcg
     2401 tcctatttta ttattttctt caaataaaat tgtagataat ttaactactt tgctagattc
     2461 tcgcaaaaca tagaaatttt cacatccagc atcattattt aatgctttta ctaatttata
     2521 gtcatatcca ttattctgcc atatttcttc taattgttta attccgtaat caaataattt
     2581 gattaaatat cgattatttt taattggccc cgggatattt aagtttatat caaccaaagt
     2641 cgcatcagga tactttttaa aaatagcttg ctgcaaagct acacgataat cttttccagc
     2701 taatacctga gcaatatttt gcggatttcc ttcttgaaaa atgttcattt atatctcacc
     2761 gcagttaatt ataaacaatt gtacctactc catcatcaag tttacttgca tttcttaaag
     2821 aagtaataat tgcagtcttt cctgttttct ctacgaaatc aatgacagct tcaatttttg
     2881 gcttcatgct gcctgcagca aattggccag cttctagata cttctttaat tgatcaatct
     2941 ttatttttcc aataggagct tgatcaggtt gattatagtt cacgtaggca ttgtcaacag
     3001 tagttagaat aactaattca tctgcttgaa tatcttcagc tagttttgcg gcactgaagt
     3061 ctttatcaat tactcctgct acgccttgca aactatcgtc tttcactaca acaggaattc
     3121 catcacctcc ggcagcaata ggaacaaact tgctctttag taaagtgtca atgcctggtg
     3181 cattaataat tttaacgggc tttggagaag aaactacttg acgatagcct cgacctgtat
     3241 cttgcttata agtatattca ggatgataga ttttttacct ctgcatttcg ttaaatgtat
     3301 aaaatgggcc aattagttta gttggattct taaaagttgg atcattcgca ttaactatta
     3361 tctgagtaat taaagcaaca gcttgatgtg gataatttgt atgtttaaat tgatcgtcta
     3421 aggccttttg catccaatag ccgatactgc cttgagtcat tgatactact gtatcaagcg
     3481 gcatagcgag attatcttta cttgaacctt tgtattgttg caaaagcaaa ttaccaacct
     3541 gcgggccatt accatgaaca atcgctacct gatcaccatt ttcaatcatt ttagcaacaa
     3601 ccttcattgt ctttttaacc tgcttttctt gggcagctgc actattatca cctgcttcaa
     3661 tagcattgcc accgaaagct acaactattc ttttcatctt tatttacttc cttcatcaac
     3721 tgacggaata aacaaattgc ccaaagtagc ggccattatt gctttgatag aatgcaatct
     3781 attttccgct tcagtaaatt gccaagcgta ttgagagtta aagacttcat ctgtaacttc
     3841 cacttcactt agaccatatt tttcataaat ttctttgcca actttagcag ttcaatcatg
     3901 aaacgcaggc aaacagtgca taaagattag ttgatcatcc ggggtgcctg tcatatacat
     3961 catattcatt gtaaccgtgt aaggctttaa caatttgatt ctctcactcc agtcattttc
     4021 acccattgat acccagacat cagtataaat aatatttgca cctttaacgc cttgttcaat
     4081 gtcatcagta atcaaatttc ttgatccaga atctttggca aaaccttctg caattttttg
     4141 tacatcaggg tgagtgaata aaggctttgg cgtaactatg tgtacattaa ctccaagcat
     4201 gctgccagcc actaaaagac tgtcggcaac attatcacgt ccatcgccta cataagctaa
     4261 agtaagtacc tttaaatgtc caaacttttc tttaatagtc ataaagtcag ccaacatttg
     4321 ggtcggatgc catttatctg ttaaaccatt ccaaacaggg acaccagaat atttagccaa
     4381 atcttctaca tctttttgag caaaaccgcg atattcaatg tcatcaaaca tactgcccaa
     4441 aaccttggca gtatcttcaa tactttcctt tttacctaaa tgaatttcac cagcacccat
     4501 atattcagga tttgcgccta aatcattgca tgcaactaca aaggctgaac gtgttcttgt
     4561 tgaagatttt tcaaataaaa gagctatatt ctttcctttt aaatattcat gcggaatatt
     4621 ttctttagtt ccttcaaatg aagtgcaaaa tcaattagat agttaagctc cgttggagta
     4681 tagtctttgc attttaataa acttctgcct tgaaacacat tttgtaaata tttcattttg
     4741 acgcctctta caaatcttca cgaacaagtg gacatgacat acatcttgga cctccacggc
     4801 cacgagaaag ctcacttgaa tgaatttcat gaactaaaat gccatgcttt cttaacaaat
     4861 catttgatac ataattacga tcatatgtaa cgacttcacc tggcgcaata gccaaagtat
     4921 tcgagccatc attccactgc tctcttgggg ctgcaattgc atccccacct ccggttggaa
     4981 ttaggtcaat ctccgataag tgcaaataat tctttaacac tttgatcaaa tcagtttctg
     5041 gggtaatttt aatctcacca tgatcatctt gctctaaaac ataaatatca atctttcctg
     5101 atttgtctaa aataaaagga tgaacagtac actaatcata attaatcatt gtaaagactg
     5161 tatccagatg catcatggca tgattatgtg gtattttaat tgctaaaatt gtgtcataac
     5221 tagaatgacc aaacaggcta tgagcaaggt cagtgattgc ggcagcggaa gttctttgag
     5281 aaataccgat tgctaaaaac atgattgttt aaaatcagct catcgccacc ttctaaacgt
     5341 ccatgagtgt aacgatcaca ccaaatagga atattggcat ttttaaagtc gggatgatgc
     5401 tttaaaacgg tttccataaa taatgactca cgtcttctag ctctaaacgt cattctatta
     5461 atagtcatgc cattaccaat agttgcttgt tgatcacgag taaaatacac atttggcatt
     5521 ggatccaaat aaaatggata atctggattt tcagctagat cggctaatga aggagttgca
     5581 ttttgcattt cattttttct aataccagca attatttgct taaccatttc atttactggc
     5641 attgctatta aatagtccat cagtaattga tgtaatggat cttctttttt atattggatt
     5701 cttctaataa ttgatctaca aattttgtac ggacatcttc attagtcaaa gagtgagcta
     5761 ataaatcttc taaataaacg acatgaactc cctatttttc caaagtgtgg gcaaaatagt
     5821 catgctcttt ttgagctatt tttaaatatg gaatatcgtc aattaacatt cgatttaaga
     5881 tatccggtga aagattttct aattctcttc ccggtcgatg cagcataact gtttctaatt
     5941 tgccaatttc ggaataaaca tgaattaagt cagtcattat agcgcctcct aattcaaatt
     6001 atgtatccgc ttacaataat taaggatcaa ttaggtagaa gttacaatct taacggctta
     6061 gtgaatctat tattcttttc attaaaggcg tcaccttttg atccttgcgc ctcactaatt
     6121 gcaaatgcgt aatccaatta ctatatttaa taggaataag atcatcaggt gcatacgtag
     6181 aagcaataga ttcaggaaca agagcaatcc ccatttttct cttcgcccaa gtaatcgctg
     6241 ttctagaatc atcacattta acagcataaa acggcttaat cccatgatga gcaaaagtct
     6301 ggttaaaaat ttcttcaaat cttcgataaa taatgagggg ctgctcattt agatctttaa
     6361 tccttaatcc cgtcttatcc ttaaatttgg gatcaacagt aactgccatc attctttcag
     6421 tagttaaagt ttttgcattt aagccattac gattataagg cgtacgcaca attcctaaat
     6481 cgattgtctt cttttccaat ttatcgataa tgccaaaggt attatcttca taaatatcaa
     6541 agttgatttc cggataaaac ttagttaaat cttgaaaact tttcatagga attagtccag
     6601 ttgatgatga agccatgcct attgcaatcg tgcctagttc acctgaaaca gttttatgaa
     6661 cctgattttt cacgctttct gataaagaga gaatttcact agcatagctc tgcaaaattt
     6721 gtccagcatc tgttaattca attccatgag cagtacgctt aaataattgt gctcctagtt
     6781 ctatttctag ttgctttaat tgataactca gcggcggttg tgcaatgtat agtcttttag
     6841 ctgctgaagt gatttgcttt tctttggcta ctactaaaaa gtagcgtaat tgtttaatat
     6901 tcattaataa tctatctttt ttattttagt tgtatctctt attaaaaatt tctatatctt
     6961 atattttaat ttagtatttt cattcaaaca acatatgtgc tactttatta aggtagattt
     7021 ggagggaata aaatgtctga aaaatttcat ggcttaactc aagccgaagc agataagaga
     7081 cttaaggaag atgggttaaa cgaagcacct gaacccgaat acaacttttt taaggaattt
     7141 ctatcaaaat tatggaatct ttctgcctgg gttctagaag gtgccttaat cctcgaatgt
     7201 atcttaggca aatggattca atctttgttc gtcttgttga tgcttctttt tgcggctttt
     7261 aacggtgcat ccaagaagaa acagtcacgg cgggtattaa ataccatttc acataagcta
     7321 acccctaagg tggctgtaga acgcgatggt aagtggatca aaattgactc taagcaatta
     7381 gttagaggcg acttaatctc acttcaacgt ggagatgtac ttgcagccga tgtaaaaatg
     7441 gttagcggta agatcgcctg tgatgaaagc tcaattaccg gtgaatctaa gcccgttaaa
     7501 aagaacattg atgacacagc ttatgctggt actactgttg ttgaaggcga tggattagca
     7561 attgttactg caactggtaa agattcaaga agtggtaaga ccattaactt gatcaacaat
     7621 tcagctgcac ctggtcactt gcaacaactt ttaactaaga ttatttacta cctttgccta
     7681 cttgacggtg tacttacctt agttattatc attgcttcat tctttaaggg tggtaatttt
     7741 gatacgttta tcaacatgtt gccattctta gccatgatgt tcatcgcttc aattccggtt
     7801 gcgatgccgt caacctttgc attgtccaat tcatttgaag caacccgttt aagtaaagaa
     7861 ggcgtcttaa cagctgattt aactggtatc caagatgcag ctaacttaaa cttgctttta
     7921 cttgataaga cgggaacaat cactgaaaac aaaactgcag ttgctagttg gagcaattta
     7981 agcgatttgc cagataaaga tgtacttgct ttagtcggta gtgcaactga taagcgcaat
     8041 gcaggtatca ttgatatcgc cattgatgaa tacttaaaag aaaacgatat ccctgtcatg
     8101 gacgttgaac actttacccc atttacttct gacactggct attctatggc tgaagtagat
     8161 ggtcacaatg ttaagttagg ttcatttaag caactttcat taatcgataa gaatgcaaat
     8221 gaagcagttg aaggcatcaa ttttaaagct ggacgctcag ttgccgtgtt aattgatgac
     8281 aaacttgcgg gagtatttat cttacaagat aaagtaagaa aggactctaa ggctgcttta
     8341 gcagaactta aaaaacgggg cgtacgtcca atcatgttaa ctggtgataa tcaaagaact
     8401 gccgcagcag tcgctgaaca agttgattta actggtaacg ttatctctat tcatgacttt
     8461 gatgaaagca ccgatattga tgaattagca ggaattgccg atgttttacc tgaagataaa
     8521 cttaagatgg ttaaattctt ccaagaaaaa ggttatatcg ttggtatgac tggtgatggt
     8581 gttaacgact ctcctgcttt aaagcaagct gaagttggta ttgctgtttc taacgctgcc
     8641 gatgttgcca agcgttcaag taagatggtg cttctagatg atggcttaag ctctattgtt
     8701 aaaattcttg atgctggtca ccgtgtatat caacgaatga ctacttggtc acttgctaag
     8761 ctcgccagaa ccgccgaatt aactatgctt ttaaccttcg gctatctctt cttcaactat
     8821 attccaatgg cattaaatgc tatggttatt tacacaatca tgaataacat ggttaccatg
     8881 atgattggta ccgaccgtac ccatattact tacaaaccag aaaattggaa tatggcaagg
     8941 ttagccaaaa tcgcattctc tcttgctgca ggttggacag ttatcggtat cgcttttttc
     9001 agctacctca acatgcatgg ctggagtcac aattctatct ctaccatggt ctatgtttac
     9061 ttagttctaa gtgcaatgtt aattgtatta attactagaa ctcgtaaata cttctggcaa
     9121 gattatccat ctaaacttgt aggtattgtt caaattgccg atgtcgcatt aacctttatt
     9181 ttagctttat gcggtttagc aatggctcaa attagttggc aaaacttatt aattaccgtt
     9241 gtggttgcat taattgcagc aattattatt gatttgattt atcaaccagt aatgaaaaac
     9301 agataattaa cttaaaacaa aaacactctg aaaactaaat tactacaatg tagttttcag
     9361 agtgtttttt ttgattaata attagtaact gtagtcaagg cattcaaagc cttaacatat
     9421 tcaccatcag caattttgat aaatggtttt tcattaattt ctttatggcc taaatagtta
     9481 accttagcac cacgctttaa aaatttgcct gggatttttt caccattctc atcataaaca
     9541 aaggaatgct ttttgattct attaactact tttacagtag tcttcatata tggcaagaag
     9601 gcttcttcct taacaaatct atttttacga atctttacat aagtattacc attaattact
     9661 tttatggcac gtactttgta aagctttccc tttcttaaat gtccaacttt aacaccatgt
     9721 ctattataaa cagtagcatt tctagttaga tttaatctct taccttgtct aactggatta
     9781 gtaacaactg catcaacgct ttgtgtagtt gctgcgccta atccaataac tgctaacatt
     9841 atacctgcag cagaaataat ttgttttctc atcataatcc acccccgtag tgtttatacc
     9901 attctccatc ccttatttta tcaaaaatta tcgaattgga agcatttttt actcatctgt
     9961 tttataacta tttgcttaat tctgctaaaa ttatttataa cactacttaa ttcatgattt
    10021 taacttggga tataatccgt aggactatcg aagtcttatg gattatcaat attgcgtttg
    10081 ctgtatggac ggtctttaga agtcgccgca gcgttgttgc aacttgggca tagatgcttg
    10141 tattaaccgt tctgcccggt atcggtttta tcctatatct tttctttggt cgtcagcttt
    10201 cacatgatga aatctttgct attcaagaag agcaaaaaaa ggtacaaaga cattatttag
    10261 ctgagcaacg cgacatgctt aaagagcacg atcttctacc tgaaaaagag cgtcttccac
    10321 gagtaagaat gctttcggaa ctaaatctta acaacgatga tgcgatttta acttttgata
    10381 atcaggtcaa agtatttatt tctggaccag aactttttga ccaaatgatt actgatatca
    10441 aaaatgccaa aaaatctgtc agcttagaat tatatacttt ttattctaac caattagggc
    10501 atcgtgtttt aaaagccttg gaagaggctg cagctaatgg tgctaaggta agagtaattt
    10561 atgatacctc tggatcaaga ggcactaagc caagcttttt tgaccattta agggcggcga
    10621 agctcagcca tttatttcca cttcaaaaaa gcactggttt actaccccac gactcaatta
    10681 ccacttacat agaaaattag ttattattga ccaccatatt ggctatattg gcggatttaa
    10741 tattggagat caatatgtca ataaatcacc aaaattcggt cattggcggg atacccattt
    10801 acgtgtaatt gggcaatcac caattctaat ggaggtccgg tttgcaatgg actggaacac
    10861 gtcaatcaga agaacaaatt tacctaaatt tgaattaaag gaacttaaac catttactgt
    10921 caatcgaaaa gatatcaatg ataataaaaa tgtcgctatg caattgtttc ctcaggacct
    10981 gataatcaac attacggcat cagacgaggc tgagggaatt attgcaggag ctaaaaaata
    11041 catttatatt caaacgcctt atttaattcc cgaagaatca attcttgaag ccttaattat
    11101 cgctgctaac agcggtattg atgttcgaat tatggttcct tgcatgcccg atcatccatt
    11161 tgtttatcgt gctacagaat actatgctaa gtatttagta gcccatggcg ttaaagtata
    11221 caaatataat gatggtttta ttcatgcaaa aactatggtt agcggttcta atatttcttc
    11281 agttggttcc gccaatcaag atttccgaag ctatacatta aactttgagg taaactcatt
    11341 caactacaac cctgctttaa ctcaagaatt aaagaaaatt tttgagaagg acttagataa
    11401 atgtaccctt ttaactaatg actactttgc tcaacaatca tcatggttaa aatttaagca
    11461 atacttctca agattattat cacctatttt ttaatgaaaa gccctctatc ggtttatccg
    11521 atagggattt tactttgtat tttaaaaatg cagttttatt tctttactta ttttttatag
    11581 gttatataat gataactatt aaaaagtaag gaggataaaa cttggctaat agagtaaaaa
    11641 taggcgtttt gaatttaatg cacgataagt tagatactca acaaagattt gcacgcgttt
    11701 tgccagatgc agacctgact ttcttttatc cacgtatgca ttatcaaaat cgtcctgtcc
    11761 cacctgaagt tgcaaaaact tcccagccat tagatcttaa tcaaatcaaa gagtttgatg
    11821 gctttatcat tacgggcgca cctttagatc atcttgattt tgatcaagtt acctacatcg
    11881 aggaagtccg atgtttgctc caactattag ataaatacaa gttgcagcaa ttatattttt
    11941 gctggggtgc aatggccgct ttagattatt tttacaatat tcaaaaaaga attttatcga
    12001 aaaaaatctt tggtgttttt cctcatttaa ttatcgaacc acatccttta ttaaatggac
    12061 tcagcaaagg atttatcgct ccacatgctc gttacgctga aatggataaa acacagatta
    12121 tgcaagatcc acgattaacc attaattcag ttgacgataa tgggcatcta tttatggtct
    12181 cttctttaga aaagcctgag caaaatttta ttttctctca tatcgaatat ggccgaaaag
    12241 gccttaaaaa agaatatgaa agagagattg ctgcacatcc agagcgacat tataagaagc
    12301 cagaaaatta ttcattatca aatctattgt ttcaatggaa agatactcag aaaacatttt
    12361 tcaataactg gctaactcaa gttaaaaaaa gcaaattagt attattagat aaataaaacg
    12421 aggcatacat tatgtctaca atttataatt cagttacaga acttatcggc aacactccat
    12481 tacttaagtt gaatcgcgtt gtacctgacg acgcggcaga tgtctatgta aagttagaat
    12541 ttgaaaaccc agctggttca attaaagaca gaattgcttt agctatgatc gaaaaagctg
    12601 aacgtgaagg caacctaaag ccaggtggca caattgtaga acctacttca ggcaataccg
    12661 gtatcggttt agccatggtt gctgcagcta aggactatca cattattatt gttatgccag
    12721 aaactatgag cgttgagcgg cgtaaattaa tgaagggcta tggtgctgaa cttattttga
    12781 caccaggtgc agacggtatg aagggttcaa ttgctaaggc cgaagaatta gttaaagaga
    12841 aaggctactt catgccaatg caatttgaaa atacagaaaa tcctaatatt catgaattaa
    12901 ctactggtcc agaaattatt gccgcaatga atggtatcgg caaatccgtt gatgcctttg
    12961 ttgctggtgt tggtactggt ggtactttat caggaattgg acatgcactt aggcgtgaaa
    13021 atccatccac taagatattt gcacttgagc caactgaatc tccactctta aaaaatggaa
    13081 aaacaggtaa acatggtatc caaggtattg ccgcaggttt catccctaag aatttagata
    13141 aggatatcta cgatgatata attacagttt ctactgatga agcaatggct acagctcgtg
    13201 aagtagctaa aaacgaaggc ttcttacctg gtatttcagc tggtgcaaac atccatggtg
    13261 caatcgaaat tgctaaaaag ttaggcaagg gacatgctgt ggttactgta gttccagacg
    13321 gcggtgatcg ttacctttca actgcattat ttaatgctta aaacttaatt tctgtaaaca
    13381 aatactccta agtaaaattt ccttaggagt attattttta tttctgttga ttgtgcacca
    13441 gtcaatgttg gtacaacact tttagtataa tgacctttac taattagatc aatattgaat
    13501 ttatttaagc accatgatat tgcactaagc tgtaaatatc aacatcaggc aacttttctc
    13561 taccctttaa atcaggcaat tcaatgtaaa atgcagcacc tacaagctta ccaccaagat
    13621 tttcaattaa ttccttagaa gctcttaaag tacctgcagt agccattaaa tcgtcacaga
    13681 gaacaactct ttggccaggc ttaattgcat ctttatgcat ttcaaggcta tttgaaccgt
    13741 attccaagtc atatgaagca cgttcaactt ctcttggcaa cttatgtggc tttcttgctg
    13801 gaacaaaacc taagcctaac tcagttgcaa caggacagcc tacaataaag ccacgtgctt
    13861 caggacctac gattacatct gcctttctac tctttgcata ttctgccaat tcatgagtag
    13921 caatacgata caattcacca tcttgcaaaa taggtgtaat atcgcgaaag acaattccct
    13981 tattaggaaa gtccttaaca cttgcaatat atttactaaa atcaatcgcc ataagaagaa
    14041 aaacctccat aattctgtgc gtttgtattc aaacactttt gacttgtata ttttaccaaa
    14101 gatttgttat aaaagtactg aaatcttgat atttatctat ctttttacca aattattaac
    14161 atatgtaatt aatttttgag taggcatcgt tcttagttga ttaataaatt taatttgtga
    14221 actcgttgcc attaaatatt tagaagctgt caatggttgc ttctttggat tagactcacc
    14281 aactaatttt tgatcgtcta atttaacaaa acctaattca aagaatactc gcaaaataaa
    14341 caatacacta tcataatcca aacctagata tggtgctaca gtgcgatagt cttcaggctt
    14401 taatgctgga tgggcataaa tatactttaa cacttttccg aaataactct ttgctggaat
    14461 ttgttcaaca ggtaactgat ctaataaaaa gcataaataa atttgttgat aatctttttt
    14521 taaagctgca tttaattcca cttgattgcg aggcacatca agcaaagcta ctgtttcacc
    14581 cgattgatca taatctttaa ccaagctaat tttatcatca tcaatttgaa ggctattctt
    14641 aacaattgga atattctttt tgtcaaaaag caaataacga tctgcaaggc ccatgacaaa
    14701 tttctcttgt cttaaatcaa ttactgatgt tggcacagct aattttgggg atgcaaaggc
    14761 tattccttcc atgatgcctt gcaaagatac ttgtttgcga taagtattca aagagagagt
    14821 aacaaagatt tttgaaataa atggtaacaa attattattc aaataatcct tattaaatcc
    14881 cacaattgct aaattgccgt cttttttatt agctattaat ttaacatgat tcttatcttt
    14941 tcctattttg aaaaagtgtg taatagttgg atccgaaata ctaaaaattg gctgcggatc
    15001 accagtacca aatggtccca cttgattaat ttgagccaaa gtttgaggtg ataagtcatg
    15061 cataggcaat tccatatcgt actctttagt ctctaaacca ccgtcaacat gaaaatcggc
    15121 ttcaaacttt ttccgtaggt catttacttt gtcttcttcc atggataaac cacaagcaaa
    15181 atcatgacct ccaaatttgg tcaatagact ttcttttaac ggattaagag catcaaataa
    15241 gttaaaacca ctgaatgaac gacctgatcc cttaatctcc ccttcatcgt ttttagttaa
    15301 aacaattgtt ggtttatgca gtttttccac tatcttgtta gcaacaagcc ccaaaactcc
    15361 ttcatgaaaa tcaggatcat ataaaactaa agtattttgc ttttgccaac tattttcacg
    15421 aactaattcc atgcagcgat cgtaaacctc agtagttagc tctttacgct tattatttaa
    15481 gtcttcaatc tgatctgcga tcttctgtgc ctcaagatca tcatcactaa gcaaaagctc
    15541 tactgccaga ttagcattag ccaaacgtcc aacagcatta agtctaggag caatattaaa
    15601 gcctacatct gtctcattaa tcgtttctag cgttaaaccg gcatttttga taagcgctct
    15661 taagcccggt cgttcggttt gattaagaac atctaaccca cgttttacaa taatatggcc
    15721 ttcaccagta actttaacca tgtcaccaat agtaccgatc attgctaaat ctagcaattc
    15781 tggtacagga tcctgcataa gctcacgaca aattgtataa gctacacctg caccacaata
    15841 atcatcaaaa ggatattctt gaccaggata attacagtga acaattgcat aagcatctgg
    15901 cttattttct tgaaaagtat ggtgatccgt aataatagta tcaacgccat gttctttagc
    15961 gtattcaact tcttcaa
//
