LOCUS       gnlProkkaDPAPDPGF_288   6518 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DPAPDPGF_288.
ACCESSION   gnlProkkaDPAPDPGF_288
VERSION     gnlProkkaDPAPDPGF_288
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:20:38
            Original ID  :: gnl|Prokka|DPAPDPGF_288
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6518
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6518
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[254:3119]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      255..3119
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..6518
                     /SMILES="NC(C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6518
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(255..3119)
                     /NRPS_PKS="Domain: AMP-binding (8-390). E-value: 1.3e-68.
                     Score: 223.4. Matches aSDomain:
                     nrpspksdomains_ctg173_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (501-540). E-value: 1.1e-07.
                     Score: 24.2. Matches aSDomain:
                     nrpspksdomains_ctg173_1_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     184.7; E-value: 3.9e-56)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg173_1"
                     /sec_met_domain="AMP-binding (E-value: 6.9e-69, bitscore:
                     220.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.8e-09, bitscore:
                     24.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.5e-09, bitscore:
                     24.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIIDNFIQRSQNTPDQVAVKSPNGDYTYQEISNIAQQLAAKLDE
                     ENAQDIVPFYLKDTRFVLPTVIGIWLSNRIPMPLVSALDLPEATDRVKEVQWDTLITDL
                     PATLKQKNIIQVDLFNQNNHADFKAKPFSQKNVYILSTSGSTGIPKKVFLTESNLKWIL
                     TRLYSLINVNETTKFLFSTPYSFDVSLTELLSPVIAGAELVCLPTSPSNSESIRLIPKL
                     INQKQITHLSLSPSFAEALLDIVGPEAFDKLKFLMVAGEAFPINLAKKLKRALNKGCKV
                     FNLYGPTETTVYSTYHQVTENEEEYVPIGRPLPEGKVKVLDANNNEAKKGELYIGGNGV
                     TDGYLLDSVKSSSSFITLDGERYYKTGDKVEILQNGELLFLEREDDQVQVNGIRVELGE
                     IQTLVSKIADVTTAIAKFKNKRIYIFYISSQDKEAEIKSKLPTYLNPIIIKVDHFLYTY
                     NRKIDTQRMIDEYYNRSLTTDSSNTLDELKKLIAKYHANEIKELDSLDSVRFIVDVENT
                     FKIQIDDAQFSLLNTLERLAAYIDKQQTNTAAETREQANEADLLNLKLLFANFSSSYED
                     AKITASSTQQSLFSQQKPSFDLLRVSFPTINFEEIQKIRQIFTDLTTKIDLLKFAWFKD
                     RDGKLYFKKIINPAPISLVTANSFSETDLEKVMYSKPGSPIHCLIFNMKKQELNIVFSH
                     HALDASSSNKLKKIFVDLYQGNLKIEQIKSSSYAEFMSFVQEVNQSTDLKAALSLVPQT
                     QEELNLTKEDGRLYITKFACPAKTTDQIYINGLYLLSQAMMKDHKMKKITGKIALNIRK
                     FSNFDASDVIGDIHATLPWEVNENDTLTDFAKRYQMWKDHYTKGTDYRYCIFNQIGSNL
                     EYRNALSKQWSNMNISPNYIGEVNSVKAIADDILRLPFKPNYITMVSKEGVLYCISYGR
                     LLEKFKYQVKLNDEQVVTVTTNEY"
     aSDomain        complement(1500..1616)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg173_1_PP-binding.1"
                     /evalue="1.10E-07"
                     /label="ctg173_1_PP-binding.1"
                     /locus_tag="ctg173_1"
                     /protein_end="540"
                     /protein_start="501"
                     /score="24.2"
                     /tool="antismash"
                     /translation="LDSLDSVRFIVDVENTFKIQIDDAQFSLLNTLERLAAYI"
     aSModule        complement(1500..3095)
                     /complete
                     /domains="nrpspksdomains_ctg173_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg173_1_PP-binding.1"
                     /locus_tags="ctg173_1"
                     /monomer_pairings="Ala -> Ala"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1917..1982)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_1_0003"
                     /evalue="5.80E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg173_1"
                     /protein_end="401"
                     /protein_start="379"
                     /score="25.1"
                     /tool="antismash"
                     /translation="FLEREDDQVQVNGIRVELGEIQ"
     aSDomain        complement(1950..3095)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg173_1_AMP-binding.1"
                     /evalue="1.30E-68"
                     /label="ctg173_1_AMP-binding.1"
                     /locus_tag="ctg173_1"
                     /protein_end="390"
                     /protein_start="8"
                     /score="223.4"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="QRSQNTPDQVAVKSPNGDYTYQEISNIAQQLAAKLDEENAQDIVP
                     FYLKDTRFVLPTVIGIWLSNRIPMPLVSALDLPEATDRVKEVQWDTLITDLPATLKQKN
                     IIQVDLFNQNNHADFKAKPFSQKNVYILSTSGSTGIPKKVFLTESNLKWILTRLYSLIN
                     VNETTKFLFSTPYSFDVSLTELLSPVIAGAELVCLPTSPSNSESIRLIPKLINQKQITH
                     LSLSPSFAEALLDIVGPEAFDKLKFLMVAGEAFPINLAKKLKRALNKGCKVFNLYGPTE
                     TTVYSTYHQVTENEEEYVPIGRPLPEGKVKVLDANNNEAKKGELYIGGNGVTDGYLLDS
                     VKSSSSFITLDGERYYKTGDKVEILQNGELLFLEREDDQVQV"
     CDS_motif       complement(2055..2129)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_1_0002"
                     /evalue="2.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg173_1"
                     /protein_end="355"
                     /protein_start="330"
                     /score="19.7"
                     /tool="antismash"
                     /translation="GELYIGGNGVTDGYLLDSVKSSSSF"
     CDS_motif       complement(2655..2708)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_1_0001"
                     /evalue="3.80E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg173_1"
                     /protein_end="155"
                     /protein_start="137"
                     /score="13.5"
                     /tool="antismash"
                     /translation="YILSTSGSTGIPKKVFLT"
     CDS             complement(3128..4402)
                     /locus_tag="ctg173_2"
                     /transl_table=11
                     /translation="MITIAELIMFLMLLQCLWHIARTMLVNKKIKQNKNNAASFKETRD
                     EKPKFFIVIPCLQEQKIINRTIDDFVNIITSTKIDAKLFIVTTDKEKLLTNQGKTTFDI
                     VKEKIDTSDSYKDIKLLNYPGVNGMMADQLNYAFDTIYKMYDIDEKSSYFCVYNADSRP
                     GKDAFLQAKTVALKKHFPLIMQEYSAFFSNLNTLSPIMQGFAVYQTNFELINGLTNAIL
                     PSIFLRNHVVGHGLFVRFDYLKRIGSFNTEFWCEDIYLSFYLRSQGIIIEPLFALEYGE
                     SPKNIQILAKQNANWFKTLSDNKKFYQILSKNKDTKQLNTFLYYLNQVRGAFAWLLLPS
                     FYLVIFIFLIFINSGLALVFTLVYLTTTFLRFWLSNSIAKNLHGKLPVNNFLLAFESSI
                     AYLISNVGPLYLVFHRKGTKYKTER"
     CDS             complement(4438..5076)
                     /locus_tag="ctg173_3"
                     /transl_table=11
                     /translation="MSRGKIILIDGISNSGKTTLCNNLSKQLGYKIVPESIRYLENRLN
                     EKGDNILYVPKNIQEELRNQEILFDLEFDKWFDANYFADHGQNVVIDKSPYSIVATAFA
                     FESSNISGTYNKSLEFLDDFIEKAKRYKLYSPDLLLLLKADSSASSKRNLERNHHLLSV
                     WTQESTRQKQEEILEKEFQELDMKKALIDTSNLSPRDVYDEALKQITSL"
     CDS             5228..6454
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 242.2; E-value: 1.5e-73)"
                     /gene_kind="transport"
                     /locus_tag="ctg173_4"
                     /transl_table=11
                     /translation="MTEEAKLTKTEKLNTVKVTTSNAISKFGDVLFDYVNTVFLSSIPN
                     GGFWLSFYQSSEVLISVFFNFWGGAVSDSGNRKRIIFHCDLISGFICLILAIFIPKSFF
                     IYAIILINIALAIITSFRSPAYKAIFREIVYKEHINTVNSTLEIVKEIVQIAGPSLALL
                     IANFFGNRIALVLDAVSFFVSGLLIKKLTILKKLTILTTQPNKKHKKNTLFQIREGFQY
                     ILTNSQIMMIIIFSSIVNFIIAGYNLILPFSTYAFSGTTLKAYAVFLTAESVGGLIGAS
                     VSTFLKREPTTNRLILFITLCGASLIFVQQLFQLSHSIILVATLIVLFNLFLSIFNIQF
                     MTFIQIKTDINYIGRVFGIIFSVAILFMPFGTFFFQRIFDLKNPYNYLILGLSLVVISL
                     LRVVLVKSF"
ORIGIN
        1 ttttctaact taattagctt cattcgtacc aataattcta ataaaataat ctattaaatt
       61 attgatatta cttgacttaa ggtagaaaaa gaaccgaatc aaaatgattc ggttcatcaa
      121 gtcagatcat caatcaatgt cttaacttaa tgacattgga ctccgataga atatcgaaat
      181 caagctttaa aagaatttat ttaaaactaa cgtccaactt taggggttag cttcatagct
      241 tagttggctt ttttctaata ttcatttgtt gttacagtaa ctacttgctc atcattcaat
      301 ttcacctgat acttaaattt ttcgagtaag cgcccatatg aaatgcaata tagcacacct
      361 tctttcgaaa ccatagtgat gtaattaggc ttgaacggca gccttaagat atcatccgca
      421 atcgccttta ctgaatttac ctctccaata taattaggtg aaatattcat gttgctccac
      481 tgtttactta aagcgttgcg atattctaaa ttactgccaa tctgattgaa aatgcagtag
      541 cgataatccg tgcccttagt atagtgatct ttccacattt gatatctctt ggcaaaatca
      601 gtcaaagtat cattttcatt cacttcccaa ggtagggtag cgtgaatatc tccaattaca
      661 tcgctagcat caaagttcga aaacttcctg atattcaaag cgatctttcc cgtaatcttc
      721 ttcatcttat gatctttcat catcgcttgt gacagtaagt aaagaccgtt aatgtaaatt
      781 tgatccgtcg ttttagcagg gcaggcgaat tttgtgatat agagtcgacc atcttcttta
      841 gttaaattga gttcttcctg cgtttgaggt accaaagaaa gggccgcctt taaatcagta
      901 ctttgattaa cttcttgaac aaaactcata aattcagcat aagaactgga cttaatttgc
      961 tcaattttca aatttccttg atacaaatct acgaatattt tcttcaattt gttagaagaa
     1021 gaggcatcta gagcgtggtg tgaaaagaca atgtttaact cctgcttctt catattgaaa
     1081 ataaggcaat gaattggcga accaggctta gaatacatca ctttttctaa gtcagtttcg
     1141 gaaaagctgt ttgcggtaac aagtgagatt ggagctggat tgattatctt cttgaaatat
     1201 agtttaccgt ctcgatcttt aaaccaagca aatttcaata gatctatctt agtagttaaa
     1261 tcagtaaaaa tctgtctaat cttctgaatt tcttcaaagt taattgtcgg aaaagatact
     1321 cttagcaggt caaaagatgg tttttgttgt gaaaagagac tctgctgcgt tgatgaagca
     1381 gtaattttcg catcctcata gctgctcgaa aagtttgcaa acagcaattt aagattaagt
     1441 aagtcagctt catttgcttg ctcgcgagtc tctgcagctg tatttgtttg ctgcttgtca
     1501 atatatgctg ccaagcgctc aagcgtgttc aacagtgaga actgggcatc atcaatctga
     1561 atcttaaaag tattttctac atcaacaatg aagcgcactg aatccagaga atccagctct
     1621 ttaatttcat tagcgtggta tttggctatc aactttttca attcgtctaa agtgttagag
     1681 ctatcagtag tcaaagaacg attataatac tcgtcgatca ttctttgcgt atcaatctta
     1741 cggttgtagg tgtacaagaa gtgatcgacc ttaataatta ttggattgag ataagttggc
     1801 agtttacttt taatctcagc ttctttatct tgcgaactaa tgtaaaaaat atagattcgc
     1861 ttgtttttga acttcgcaat tgctgtggta acatcagcga ttttcgatac tagagtttga
     1921 atttcaccta attccacacg gattccgtta acttggactt gatcgtcttc tctttctaag
     1981 aaaagtagct caccgttttg taaaatttct accttatcac cagttttata atagcgttca
     2041 ccgtcaagag tgatgaagct tgagctgctt ttaacagaat ctaaaagata gccgtctgtt
     2101 actccatttc cgccaatata taattcacct ttttttgctt cattattgtt tgcatcaagg
     2161 acttttacct ttccctctgg taatgggcgg ccaatcggta cgtattcttc ttcattttca
     2221 gttacctgat gataagtaga atagacagtt gtttcagtcg gaccataaag attaaaaact
     2281 ttgcatccct tattaagcgc ccgtttcaat ttttttgcca aattaatcgg aaatgcttca
     2341 ccggctacca tcagaaactt gagtttatca aaggcttcag gaccaacgat atcaagaagt
     2401 gcctccgcaa atgaagggga taaggaaagg tgcgttattt gcttttgatt aattaatttg
     2461 ggaattagcc tgatactctc tgaattagaa ggacttgttg ggagacaaac cagctcggca
     2521 ccggcaataa cgggcgacag aagctctgtt aatgaaacat caaaagaata aggcgttgaa
     2581 aataaaaatt tggtcgtctc gttgacgtta attaatgagt acagtcttgt aaggatccac
     2641 tttagattgc tttctgtcag aaaaactttt ttaggaatgc cggtactgcc agaagtagag
     2701 aggatgtata catttttttg cgagaacggt ttagctttaa agtcggcgtg attattctga
     2761 ttgaaaagat caacttgaat gatatttttc tgcttaagtg tggcaggtaa gtcagttatt
     2821 aaagtatccc attgaacttc ttttacacga tcagtggctt caggtaggtc taacgctgat
     2881 acaagtggca tagggatgcg gttggatagc caaattccaa ttactgtggg cagtacaaaa
     2941 cgggtatctt ttaaataaaa gggaacgatg tcctgagcat tttcctcatc aagtttagcg
     3001 gctaattgct gggcaatatt ggaaatttct tgataggtat aatcaccatt tggtgattta
     3061 actgccactt gatcaggagt attctggctg cgttgaataa aattatcaat aataaacata
     3121 ctgaaactca cctttctgtt ttatatttag ttccttttct atgaaatact agatagagag
     3181 gacctacatt agaaattaaa tatgctatgc tactttcaaa cgctagaagg aaattattta
     3241 ccggtaattt tccgtgtaaa tttttcgcga ttgaattaga taaccagaat cgaagaaatg
     3301 tggtagttag ataaactaaa gtaaaaacta gtgctaatcc actatttata aaaataagaa
     3361 atataaagat aactagataa aagctaggta gtaatagcca tgcaaaggct cctcttactt
     3421 gatttagata ataaagaaaa gtattcaatt gtttagtatc tttattctta cttaatattt
     3481 gataaaattt tttattatca gacaatgttt tgaaccaatt agcattttgt ttagcaagta
     3541 tttgaatatt tttaggagat tccccatatt ccaaggcaaa taatggttca attataattc
     3601 cctgacttct caaatagaaa ctaagataaa tatcttcaca ccaaaattca gtattaaagc
     3661 tacctattcg ttttaaataa tcaaatctga caaaaagtcc atggcctaca acatgattcc
     3721 ttaagaaaat agaaggtaat atagcatttg ttagtccatt tattaattca aaattagttt
     3781 gataaacagc gaagccttgc ataattggac ttaacgtatt taagttagag aaaaatgcag
     3841 aatattcttg cataattaaa ggaaaatgct tctttagggc aactgttttt gcctgaagga
     3901 atgcgtcttt tccggggcga ctatcggcat tatagacaca gaaataggag cttttctcat
     3961 caatatcata cattttataa attgtatcga atgcataatt taattgatca gccatcatgc
     4021 catttactcc aggatagttt aaaagtttaa tgtctttata actatctgat gtatcaatct
     4081 tttcttttac aatgtcaaat gtagtttttc cttgattggt tagcaatttt tctttatcag
     4141 tagttacgat gaataatttt gcatcaattt ttgtactagt aataatattt acaaaatcat
     4201 ctatcgttct attaattatc ttttgttctt gtaaacatgg aataactata aagaattttg
     4261 gtttttcatc tctagtttct ttaaagctcg cagcattatt tttattttgc tttatttttt
     4321 tattcactag cattgttcta gctatgtgcc acaaacattg tagtagcatt agaaacatta
     4381 ttaattctgc tattgttatc ataattagcc ctccttaata aaatttgatg agttaaatca
     4441 caaactagtg atttgtttta aagcctcatc atagacatcc cgtggtgaaa gatttgatgt
     4501 atcaattagt gcctttttca tgtctaattc ttgaaattct ttttctaata tttcttcttg
     4561 cttttgtctt gtactttctt gagtccagac acttaaaagg tgatgattcc gttccaaatt
     4621 tctctttgat gaagcagaac tatcagcttt taatagtaat agcaagtccg gactgtataa
     4681 tttatatcgt ttagcttttt ctataaaatc gtctaaaaac tctaacgatt tattatatgt
     4741 tccagatata ttagaagatt cgaaagcaaa tgctgtcgca acgattgaat agggtgattt
     4801 atcaattaca acattttgtc catgatcagc aaaataattt gcatcaaacc atttatcaaa
     4861 ttctaggtca aataatattt cctgattccg taattcttct tgaatatttt taggaacata
     4921 taaaatatta tctccttttt catttaacct attttctaga tatcttattg attcaggaac
     4981 aattttataa cctagttgtt ttgataagtt attacataaa gtagttttac ctgaattcga
     5041 tatgccatct ataagtatta tttttcctct actcataata ttaatatctt cctttcttaa
     5101 gaaacaagat gcataacttt tttgttaaag cttttttaat agtgctataa tttattaaca
     5161 atcatttatt ttaattaatt ttattctcat ttatttcaaa gtcaatactt tttatgaagg
     5221 tgattcaatg acagaagaag caaaattaac aaaaacggaa aagctaaata cggttaaggt
     5281 tactaccagt aatgcgattt cgaaatttgg tgatgtttta tttgactacg taaatacagt
     5341 atttctttct tctattccaa atggaggttt ttggctgtct ttctaccaaa gtagtgaagt
     5401 tttaatcagc gtatttttta atttttgggg aggtgctgtc tctgacagtg gtaatagaaa
     5461 gcgaattatt tttcattgtg atttgattag tggatttatt tgtcttatat tagcaatttt
     5521 tattcctaag tcatttttta tttatgcgat tatacttatc aatattgcac tagcgataat
     5581 cacgtcattt cgaagcccag catataaagc gatttttaga gaaattgttt ataaagaaca
     5641 cattaatact gttaattcta ctttggaaat tgtaaaagaa attgttcaaa ttgctggacc
     5701 tagtttagct ttgttgatcg ctaatttttt cggtaataga atcgcattag ttttagatgc
     5761 agtttcattt tttgtttcag gtttactcat aaagaagctg actattttaa agaagctgac
     5821 tattttaaca acgcaaccta ataaaaagca caagaaaaat accctttttc aaattagaga
     5881 aggttttcaa tatattctga ctaattcgca aataatgatg attatcattt tctctagtat
     5941 tgtgaacttt atcattgccg gatataattt gattctacct ttttcaactt atgcttttag
     6001 tgggacaact ttaaaggcgt atgcagtttt tttaactgct gaatctgttg gtggtctaat
     6061 tggagcctca gtatcaactt ttctgaaaag ggaacccaca acaaatcggc ttattttatt
     6121 tattacacta tgtggagctt cactaatttt tgtgcaacaa ttatttcaac tatcgcattc
     6181 tattattctt gtagcgacgt taatcgtcct atttaatctt tttttgtcga tcttcaatat
     6241 tcaatttatg acattcattc agattaagac tgatattaat tatataggca gagttttcgg
     6301 aattattttt tcggttgcaa ttctctttat gcctttcggt acttttttct tccaaagaat
     6361 ttttgatctt aaaaaccctt ataattactt aattttagga ctttcgttag tcgttatatc
     6421 tttgttacgc gtggtgctag ttaaatcgtt ttagttaaat aaaaagtcca atcttgttag
     6481 actcgacttg taaatagtaa taatagaaaa gagtctga
//
