LOCUS       c00192_gnlPro..        15988 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KOILBHMK_314.
ACCESSION   c00192_gnlPro..
VERSION     c00192_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 15:12:12
            Original ID  :: gnl|Prokka|KOILBHMK_314
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15988
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15988
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2775:5988]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2776..5988
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..15988
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15988
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(151..756)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg192_1"
                     /sec_met_domain="LysR_substrate (E-value: 9e-19, bitscore:
                     58.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDAVIKDFILLAKKVY"
     CDS             complement(759..920)
                     /locus_tag="ctg192_2"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMFNKYQIRKDKKQISDE
                     GHAPLDEN"
     CDS             complement(936..2102)
                     /locus_tag="ctg192_3"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMPRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLACMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             complement(2223..2759)
                     /locus_tag="ctg192_4"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGAIKNNRYLIKLFDYGIKQLEEIWQNNGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             complement(2776..3117)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg192_5"
                     /sec_met_domain="AA_kinase (E-value: 3.3e-19, bitscore:
                     60.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             complement(3286..3708)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg192_6"
                     /sec_met_domain="AA_kinase (E-value: 4.4e-13, bitscore:
                     39.9, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVAFGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNLAMPLDTVVSMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKLIGPFYTFNEMQR"
     CDS             complement(3903..4511)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg192_7"
                     /sec_met_domain="OTCace (E-value: 1.9e-37, bitscore: 119.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1.3e-24, bitscore:
                     77.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDDIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKVLTLAYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMNMMYMTGTPDDQLIFMHCLPAFHD"
     CDS             complement(4610..4747)
                     /locus_tag="ctg192_8"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSLLKCKDYTPTELNYLIDFALHLKELKKIFRMNI
                     "
     CDS             complement(4759..5031)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg192_9"
                     /sec_met_domain="Amidinotransf (E-value: 7.6e-31, bitscore:
                     97.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLKNYLHLSEIDLIPTGGGDAIAAPREQWNDGSNTLAIAPGEVVT
                     YDRNYVSNDLLRKHGILVHEIHSSELSRGRGGPRCMSCPLVREDL"
     CDS             complement(5261..5671)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg192_10"
                     /sec_met_domain="Amidinotransf (E-value: 2.6e-28, bitscore:
                     89.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEMQNATPSLADLAENPDYPFYL
                     DPMPNVYFTRDQQATIGNGMTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWCDRY
                     THGRLEGGDELILNNHVFSNRYFSKNFRCRNH"
     CDS             complement(5803..5988)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg192_11"
                     /sec_met_domain="Amidinotransf (E-value: 1.9e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             complement(6061..6915)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     72.5; E-value: 6.7e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg192_12"
                     /sec_met_domain="LysR_substrate (E-value: 2.1e-28,
                     bitscore: 89.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.5e-23, bitscore: 72.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAKEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKFKDKTGLRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKYSNWITHLQLVRRKDQKVTPLMKRIIDS
                     LSR"
     CDS             7044..9317
                     /locus_tag="ctg192_13"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSNLSDLPDKDVLALVGSATDKRNAGII
                     DIAIDEYLKENDIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(9386..9883)
                     /locus_tag="ctg192_14"
                     /transl_table=11
                     /translation="MRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTRN
                     ATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVVN
                     RIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVT
                     NY"
     CDS             10145..10711
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg192_15"
                     /sec_met_domain="PLDc_2 (E-value: 2e-09, bitscore: 28.1,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLTVLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQ
                     RDMLKEHDLLPEKERLPRVRMLSELNLNNDDAILTFDNQVKVFISGPELFDQMITDIKN
                     AKKSVSLELYTFYSNQLGHRVLKALEEAAANGAKVRVIYDTSGSRGTKPSFFDHLRAAK
                     LSHLFPLQKSTGLLPHDSITTYIEN"
     CDS             10858..11505
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg192_16"
                     /sec_met_domain="PLDc_2 (E-value: 6.9e-28, bitscore: 87.8,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDWNTSIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQLFPQDL
                     IINITASDEAEGIIAGAKKYIYIQTPYLIPEESILEALIIAANSGIDVRIMVPCMPDHP
                     FVYRATEYYAKYLVAHGVKVYKYNDGFIHAKTMVSGSNISSVGSANQDFRSYTLNFEVN
                     SFNYNPALTQELKKIFEKDLDKCTLLTNDYFAQQSSWLKFKQYFSRLLSPIF"
     CDS             11633..12427
                     /locus_tag="ctg192_17"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSKGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             12443..13372
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg192_18"
                     /sec_met_domain="PALP (E-value: 5.9e-69, bitscore: 223.2,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIIYNSVTELIGNTPLLKLNRVVPDDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKDYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEELVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKDGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGDRYLSTALFNA"
     CDS             complement(13516..14043)
                     /locus_tag="ctg192_19"
                     /transl_table=11
                     /translation="MAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRIATHELAEY
                     AKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLE
                     MHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKGREKLPD
                     VDIYSLVQYHGA"
ORIGIN
        1 gtccattttg acctcgtttc taaatgttgt gtggtaacta cattctatca aacaggtccg
       61 aatggacttt ttatttttta tcaagtgttc aacttaattt tacaatcagc gcatttttat
      121 ttttacagta ttttgctgtt ccaagataga ttaatatact tttttagcta acaaaataaa
      181 atctttaatt actgcatctt cattggtata aaaagctgca atcttttgcc acatttgttg
      241 tccattagac aataaaaaca atcgttgtaa agtatcatta ctaattaaac tggcggttgc
      301 ttcattcatt aaaaaatatc ctgatccaga agctactaac aatgctgcct cttctacgga
      361 atttgaagca atgaatgggc ttctaatctg ataaatatct ttaaataaat ggagttctgc
      421 agcctcttct tcaggcttag ctacaataaa acaggttaaa tcagctagat catctttatt
      481 gatcatctga acaccgctag gataactacc cttttgcaaa atagccatta ctgcttcctg
      541 acctaagatt tctttcttaa aatcgagctg atcatcgcgc aaatcactaa tcgctaaatc
      601 aacttcattt ttggctaatt tatcaaaagc ttcatcgtgt cccattccaa ttaattcaat
      661 ttctacatca gaatgttttt gcttaaattg gtctacaatt cgatctaatt gtcttctacc
      721 aagttggtta aagtatgcta ttctcaattt tttcatagtt aattttcatc caatggggca
      781 tgaccttcat ctgatatttg ttttttatct tttctaattt gatatttgtt gaacataatc
      841 aatagcgaaa taaccacatt tattccacta actaccacgc ttaaaaattt tagtaatcta
      901 actttctttt gcttactcat tttggatacc ttcttctaaa aataatcata aaatgagact
      961 ttacctttta caaagtccaa ctttttaatt cgataatctg tgatcaaacc aagtttaatt
     1021 gcggattcca tagttaaacg tcctaataag atttgagtcc atgttgtaat tggaccagag
     1081 aaatcaacta gttcatcttc ttttcgttca cacttaactt ggtgatcata attagttaat
     1141 tgccaaacgc caatattcca tggacactga tcatcataat taacttcgat gttaaaagta
     1201 ccctcttgca atgggcgcat gcatgccaag actttttgga aatcaataat tctactcatc
     1261 atatatggat gaagttgaat atccaattca ttttgctctg gaaaaagttc agccaataaa
     1321 gacttctcag gcaatgtcat acaaaactct ttaattgacc ctatatgagc tgccataaag
     1381 cctaatatgc ttaataatcc ttgaggcgta attgaatata attcatcagc cataaaacag
     1441 ttatcaatta tgcgataaat caagtagctc atcggccgac cagcttcatc gaagtaaaca
     1501 gcaatctctc gatgatgata ataatcatct aatctattcc accaccaagc ttctctgatg
     1561 atcgtatttc tttcatcgtc agtatgcaac tgacgttcat ataattgaat cacaccattt
     1621 tgaacaatca aatcattcca ttttccacga attatcttac ctttgcgtgg taatctgaaa
     1681 gaagcaagtg cagcccccga aaagcgatat tctttttggt aaatactatt gctaaaacca
     1741 taatgacgat aaaatttttc tgaaaatgga gctagatttg caactgggat tttttgatca
     1801 tgcaaatcaa aaagaatttc tttcattaat ttagatatat gtccacgtcc tctgtattca
     1861 ggatatgatg ccacataacc aatacctgcc agtggaacat gatgaccaaa tatctcagct
     1921 ttaaacttat tgaccatcat ataactggtc aatttttctt gatcaaaata tccatatcca
     1981 tcactatgat catatcgggg cataaagtta ctatctgtag tcaaatcaga atcttttaaa
     2041 aaagcatatt caatcaatga agcaatttgt tttaaattgt cttggttttt ctttaatttc
     2101 atagttttcc ttacaatata tattcataac tttacttata ttttagaaca ttttatgtat
     2161 ttttcgttag ctttttttaa gatttaaatg aaaaaacggg atgattagcc tcccatcccg
     2221 ttttaattat ttacatactt cgcatataaa ctagaaatgt atctttgcat ctcttctact
     2281 gagtgtcgcc gtgatcgagc acactcttta gcagggcgat tgcataaata gcagcggcga
     2341 ctagagtatt caagctcttg gcgtgaaagt gcagttttcc ctttaattaa tacatcggca
     2401 tcaaataatc gtcctatttt attattttct tcaaataaaa ttgtagataa tttaactact
     2461 ttgctagatt ctcgcaaaac atagaaattt tcacatccag catcattatt taatgctttt
     2521 actaatttat agtcatatcc attattctgc catatttctt ctaattgttt aattccgtaa
     2581 tcaaataatt tgattaaata tcgattattt ttaattgccc ccgggatatt taagtttata
     2641 tcaaccaaag tcgcatcagg atacttttta aaaatagctt gctgcaaagc tacacgataa
     2701 tcttttccag ctaatacctg agcaatattt tgcggatttc cttcttgaaa aatgttcatt
     2761 tatatctcac cgcagttaat tataaacaat tgtacctact ccatcatcaa gtttacttgc
     2821 atttcttaaa gaagtaataa ttgcagtctt tcctgttttc tctacgaaat caatgacagc
     2881 ttcaattttt ggcttcatgc tgcctgcagc aaattggcca gcttctagat acttctttaa
     2941 ttgatcaatc tttatttttc caataggagc ttgatcaggt tgattatagt tcacgtaggc
     3001 attgtcaaca gtagttagaa taactaattc atctgcttga atatcttcag ctagttttgc
     3061 ggcactgaag tctttatcaa ttactcctgc tacgccttgc aaactatcgt ctttcactac
     3121 aacaggaatt ccatcacctc cggcagcaat aggaacaaac ttgctcttta gtaaagtgtc
     3181 aatgcctggt gcattaataa ttttaacggg ctttggagaa gaaactactt gacgatagcc
     3241 tcgacctgta tcttgcttat aagtatattc aggatgatag attttttacc tctgcatttc
     3301 gttaaatgta taaaatgggc caattagttt agttggattc ttaaaagttg gatcattcgc
     3361 attaactatt atctgagtaa ttaaagcaac agcttgatgt ggataatttg tatgtttaaa
     3421 ttgatcgtct aaggcctttt gcatccaata gccgatactg ccttgagtca ttgatactac
     3481 tgtatcaagc ggcatagcga gattatcttt acttgaacct ttgtattgtt gcaaaagcaa
     3541 attaccaacc tgcgggccat taccatgaac aatcgctacc tgatcaccat tttcaatcat
     3601 tttagcaaca accttcattg tctttttaac ctgcttttct tgggcagctg cactattatc
     3661 acctgcttca atagcattgc caccgaaagc tacaactatt cttttcatct ttatttactt
     3721 ccttcatcaa ctgacggaat aaacaaattg cccaaagtag cggccattat tgctttgata
     3781 gaatgcaatc tattttccgc ttcagtaaat tgccaagcgt attgagagtt aaagacttca
     3841 tctgtaactt ccacttcact tagaccatat ttttcataaa tttctttgcc aactttagca
     3901 gttcaatcat gaaacgcagg caaacagtgc ataaagatta gttgatcatc cggggtgcct
     3961 gtcatataca tcatattcat tgtaaccgtg taaggcttta acaatttgat tctctcactc
     4021 cagtcatttt cacccattga tacccagaca tcagtataaa taatatttgc acctttaacg
     4081 ccttgttcaa tgtcatcagt aatcaaattt cttgatccag aatctttggc aaaaccttct
     4141 gcaatttttt gtacatcagg gtgagtgaat aaaggctttg gcgtaactat gtgtacatta
     4201 actccaagca tgctgccagc cactaaaaga ctgtcggcaa cattatcacg tccatcgcct
     4261 acataagcta aagtaagtac ctttaaatgt ccaaactttt ctttaatagt cataaagtca
     4321 gccaacattt gggtcggatg ccatttatct gttaaaccat tccaaacagg gacaccagaa
     4381 tatttagcca aatcttctac atctttttga gcaaaaccgc gatattcaat gtcatcaaac
     4441 atactgccca aaaccttggc agtatcttca atactttcct ttttacctaa atgaatttca
     4501 ccagcaccca tatattcagg atttgcgcct aaatcattgc atgcaactac aaaggctgaa
     4561 cgtgttcttg ttgaagattt ttcaaataaa agagctatat tctttccttt taaatattca
     4621 tgcggaatat tttctttagt tccttcaaat gaagtgcaaa atcaattaga tagttaagct
     4681 ccgttggagt atagtctttg cattttaata aacttctgcc ttgaaacaca ttttgtaaat
     4741 atttcatttt gacgcctctt acaaatcttc acgaacaagt ggacatgaca tacatcttgg
     4801 acctccacgg ccacgagaaa gctcacttga atgaatttca tgaactaaaa tgccatgctt
     4861 tcttaacaaa tcatttgata cataattacg atcatatgta acgacttcac ctggcgcaat
     4921 agccaaagta ttcgagccat cattccactg ctctcttggg gctgcaattg catccccacc
     4981 tccggttgga attaggtcaa tctccgataa gtgcaaataa ttctttaaca ctttgatcaa
     5041 atcagtttct ggggtaattt taatctcacc atgatcatct tgctctaaaa cataaatatc
     5101 aatctttcct gatttgtcta aaataaaagg atgaacagta cactaatcat aattaatcat
     5161 tgtaaagact gtatccagat gcatcatggc atgattatgt ggtattttaa ttgctaaaat
     5221 tgtgtcataa ctagaatgac caaacaggct atgagcaagg tcagtgattg cggcagcgga
     5281 agttctttga gaaataccga ttgctaaaaa catgattgtt taaaatcagc tcatcgccac
     5341 cttctaaacg tccatgagtg taacgatcac accaaatagg aatattggca tttttaaagt
     5401 cgggatgatg ctttaaaacg gtttccataa ataatgactc acgtcttcta gctctaaacg
     5461 tcattctatt aatagtcatg ccattaccaa tagttgcttg ttgatcacga gtaaaataca
     5521 catttggcat tggatccaaa taaaatggat aatctggatt ttcagctaga tcggctaatg
     5581 aaggagttgc attttgcatt tcattttttc taataccagc aattatttgc ttaaccattt
     5641 catttactgg cattgctatt aaatagtcca tcagtaattg atgtaatgga tcttcttttt
     5701 tatattggat tcttctaata attgatctac aaattttgta cggacatctt cattagtcaa
     5761 agagtgagct aataaatctt ctaaataaac gacatgaact ccctattttt ccaaagtgtg
     5821 ggcaaaatag tcatgctctt tttgagctat ttttaaatat ggaatatcgt caattaacat
     5881 tcgatttaag atatccggtg aaagattttc taattctctt cccggtcgat gcagcataac
     5941 tgtttctaat ttgccaattt cggaataaac atgaattaag tcagtcatta tagcgcctcc
     6001 taattcaaat tatgtatccg cttacaataa ttaaggatca attaggtaga agttacaatc
     6061 ttaacggctt agtgaatcta ttattctttt cattaaaggc gtcacctttt gatccttgcg
     6121 cctcactaat tgcaaatgcg taatccaatt actatattta ataggaataa gatcatcagg
     6181 tgcatacgta gaagcaatag attcaggaac aagagcaatc cccatttttc tcttcgccca
     6241 agtaatcgct gttctagaat catcacattt aacagcataa aacggcttaa tcccatgatg
     6301 agcaaaagtc tggttaaaaa tttcttcaaa tcttcgataa ataatgaggg gctgctcatt
     6361 tagatcttta atccttaatc ccgtcttatc cttaaatttg ggatcaacag taactgccat
     6421 cattctttca gtagttaaag tttttgcatt taagccatta cgattataag gcgtacgcac
     6481 aattcctaaa tcgattgtct tcttttccaa tttatcgata atgccaaagg tattatcttc
     6541 ataaatatca aagttgattt ccggataaaa cttagttaaa tcttgaaaac ttttcatagg
     6601 aattagtcca gttgatgatg aagccatgcc tattgcaatc gtgcctagtt cacctgaaac
     6661 agttttatga acctgatttt tcacgctttc tgataaagag agaatttcac tagcatagct
     6721 ctgcaaaatt tgtccagcat ctgttaattc aattccatga gcagtacgct taaataattg
     6781 tgctcctagt tctatttcta gttgctttaa ttgataactc agcggcggtt gtgcaatgta
     6841 tagtctttta gctgctgaag tgatttgctt ttctttggct actactaaaa agtagcgtaa
     6901 ttgtttaata ttcattaata atctatcttt tttattttag ttgtatctct tattaaaaat
     6961 ttctatatct tatattttaa tttagtattt tcattcaaac aacatatgtg ctactttatt
     7021 aaggtagatt tggagggaat aaaatgtctg aaaaatttca tggcttaact caagccgaag
     7081 cagataagag acttaaggaa gatgggttaa acgaagcacc tgaacccgaa tacaactttt
     7141 ttaaggaatt tctatcaaaa ttatggaatc tttctgcctg ggttctagaa ggtgccttaa
     7201 tcctcgaatg tatcttaggc aaatggattc aatctttgtt cgtcttgttg atgcttcttt
     7261 ttgcggcttt taacggtgca tccaagaaga aacagtcacg gcgggtatta aataccattt
     7321 cacataagct aacccctaag gtggctgtag aacgcgatgg taagtggatc aaaattgact
     7381 ctaagcaatt agttagaggc gacttaatct cacttcaacg tggagatgta cttgcagccg
     7441 atgtaaaaat ggttagcggt aagatcgcct gtgatgaaag ctcaattacc ggtgaatcta
     7501 agcccgttaa aaagaacatt gatgacacag cttatgctgg tactactgtt gttgaaggcg
     7561 atggattagc aattgttact gcaactggta aagattcaag aagtggtaag accattaact
     7621 tgatcaacaa ttcagctgca cctggtcact tgcaacaact tttaactaag attatttact
     7681 acctttgcct acttgacggt gtacttacct tagttattat cattgcttca ttctttaagg
     7741 gtggtaattt tgatacgttt atcaacatgt tgccattctt agccatgatg ttcatcgctt
     7801 caattccggt tgcgatgccg tcaacctttg cattgtccaa ttcatttgaa gcaacccgtt
     7861 taagtaaaga aggcgtctta acagctgatt taactggtat ccaagatgca gctaacttaa
     7921 acttgctttt acttgataag acgggaacaa tcactgaaaa caaaactgca gttgctagtt
     7981 ggagcaattt aagcgatttg ccagataaag atgtacttgc tttagtcggt agtgcaactg
     8041 ataagcgcaa tgcaggtatc attgatatcg ccattgatga atacttaaaa gaaaacgata
     8101 tccctgtcat ggacgttgaa cactttaccc catttacttc tgacactggc tattctatgg
     8161 ctgaagtaga tggtcacaat gttaagttag gttcatttaa gcaactttca ttaatcgata
     8221 agaatgcaaa tgaagcagtt gaaggcatca attttaaagc tggacgctca gttgccgtgt
     8281 taattgatga caaacttgcg ggagtattta tcttacaaga taaagtaaga aaggactcta
     8341 aggctgcttt agcagaactt aaaaaacggg gcgtacgtcc aatcatgtta actggtgata
     8401 atcaaagaac tgccgcagca gtcgctgaac aagttgattt aactggtaac gttatctcta
     8461 ttcatgactt tgatgaaagc accgatattg atgaattagc aggaattgcc gatgttttac
     8521 ctgaagataa acttaagatg gttaaattct tccaagaaaa aggttatatc gttggtatga
     8581 ctggtgatgg tgttaacgac tctcctgctt taaagcaagc tgaagttggt attgctgttt
     8641 ctaacgctgc cgatgttgcc aagcgttcaa gtaagatggt gcttctagat gatggcttaa
     8701 gctctattgt taaaattctt gatgctggtc accgtgtata tcaacgaatg actacttggt
     8761 cacttgctaa gctcgccaga accgccgaat taactatgct tttaaccttc ggctatctct
     8821 tcttcaacta tattccaatg gcattaaatg ctatggttat ttacacaatc atgaataaca
     8881 tggttaccat gatgattggt accgaccgta cccatattac ttacaaacca gaaaattgga
     8941 atatggcaag gttagccaaa atcgcattct ctcttgctgc aggttggaca gttatcggta
     9001 tcgctttttt cagctacctc aacatgcatg gctggagtca caattctatc tctaccatgg
     9061 tctatgttta cttagttcta agtgcaatgt taattgtatt aattactaga actcgtaaat
     9121 acttctggca agattatcca tctaaacttg taggtattgt tcaaattgcc gatgtcgcat
     9181 taacctttat tttagcttta tgcggtttag caatggctca aattagttgg caaaacttat
     9241 taattaccgt tgtggttgca ttaattgcag caattattat tgatttgatt tatcaaccag
     9301 taatgaaaaa cagataatta acttaaaaca aaaacactct gaaaactaaa ttactacaat
     9361 gtagttttca gagtgttttt tttgattaat aattagtaac tgtagtcaag gcattcaaag
     9421 ccttaacata ttcaccatca gcaattttga taaatggttt ttcattaatt tctttatggc
     9481 ctaaatagtt aaccttagca ccacgcttta aaaatttgcc tgggattttt tcaccattct
     9541 catcataaac aaaggaatgc tttttgattc tattaactac ttttacagta gtcttcatat
     9601 atggcaagaa ggcttcttcc ttaacaaatc tatttttacg aatctttaca taagtattac
     9661 cattaattac ttttatggca cgtactttgt aaagctttcc ctttcttaaa tgtccaactt
     9721 taacaccatg tctattataa acagtagcat ttctagttag atttaatctc ttaccttgtc
     9781 taactggatt agtaacaact gcatcaacgc tttgtgtagt tgctgcgcct aatccaataa
     9841 ctgctaacat tatacctgca gcagaaataa tttgttttct catcataatc cacccccgta
     9901 gtgtttatac cattctccat cccttatttt atcaaaaatt atcgaattgg aagcattttt
     9961 tactcatctg ttttataact atttgcttaa ttctgctaaa attatttata acactactta
    10021 attcatgatt ttaacttggg atataatccg taggactatc gaagtcttat ggattatcaa
    10081 tattgcgttt gctgtatgga cggtctttag aagtcgccgc agcgttgttg caacttgggc
    10141 atagatgctt gtattaaccg ttctgcccgg tatcggtttt atcctatatc ttttctttgg
    10201 tcgtcagctt tcacatgatg aaatctttgc tattcaagaa gagcaaaaaa aggtacaaag
    10261 acattattta gctgagcaac gcgacatgct taaagagcac gatcttctac ctgaaaaaga
    10321 gcgtcttcca cgagtaagaa tgctttcgga actaaatctt aacaacgatg atgcgatttt
    10381 aacttttgat aatcaggtca aagtatttat ttctggacca gaactttttg accaaatgat
    10441 tactgatatc aaaaatgcca aaaaatctgt cagcttagaa ttatatactt tttattctaa
    10501 ccaattaggg catcgtgttt taaaagcctt ggaagaggct gcagctaatg gtgctaaggt
    10561 aagagtaatt tatgatacct ctggatcaag aggcactaag ccaagctttt ttgaccattt
    10621 aagggcggcg aagctcagcc atttatttcc acttcaaaaa agcactggtt tactacccca
    10681 cgactcaatt accacttaca tagaaaatta gttattattg accaccatat tggctatatt
    10741 ggcggattta atattggaga tcaatatgtc aataaatcac caaaattcgg tcattggcgg
    10801 gatacccatt tacgtgtaat tgggcaatca ccaattctaa tggaggtccg gtttgcaatg
    10861 gactggaaca cgtcaatcag aagaacaaat ttacctaaat ttgaattaaa ggaacttaaa
    10921 ccatttactg tcaatcgaaa agatatcaat gataataaaa atgtcgctat gcaattgttt
    10981 cctcaggacc tgataatcaa cattacggca tcagacgagg ctgagggaat tattgcagga
    11041 gctaaaaaat acatttatat tcaaacgcct tatttaattc ccgaagaatc aattcttgaa
    11101 gccttaatta tcgctgctaa cagcggtatt gatgttcgaa ttatggttcc ttgcatgccc
    11161 gatcatccat ttgtttatcg tgctacagaa tactatgcta agtatttagt agcccatggc
    11221 gttaaagtat acaaatataa tgatggtttt attcatgcaa aaactatggt tagcggttct
    11281 aatatttctt cagttggttc cgccaatcaa gatttccgaa gctatacatt aaactttgag
    11341 gtaaactcat tcaactacaa ccctgcttta actcaagaat taaagaaaat ttttgagaag
    11401 gacttagata aatgtaccct tttaactaat gactactttg ctcaacaatc atcatggtta
    11461 aaatttaagc aatacttctc aagattatta tcacctattt tttaatgaaa agccctctat
    11521 cggtttatcc gatagggatt ttactttgta ttttaaaaat gcagttttat ttctttactt
    11581 attttttata ggttatataa tgataactat taaaaagtaa ggaggataaa acttggctaa
    11641 tagagtaaaa ataggcgttt tgaatttaat gcacgataag ttagatactc aacaaagatt
    11701 tgcacgcgtt ttgccagatg cagacctgac tttcttttat ccacgtatgc attatcaaaa
    11761 tcgtcctgtc ccacctgaag ttgcaaaaac ttcccagcca ttagatctta atcaaatcaa
    11821 agagtttgat ggctttatca ttacgggcgc acctttagat catcttgatt ttgatcaagt
    11881 tacctacatc gaggaagtcc gatgtttgct ccaactatta gataaataca agttgcagca
    11941 attatatttt tgctggggtg caatggccgc tttagattat ttttacaata ttcaaaaaag
    12001 aattttatcg aaaaaaatct ttggtgtttt tcctcattta attatcgaac cacatccttt
    12061 attaaatgga ctcagcaaag gatttatcgc tccacatgct cgttacgctg aaatggataa
    12121 aacacagatt atgcaagatc cacgattaac cattaattca gttgacgata atgggcatct
    12181 atttatggtc tcttctttag aaaagcctga gcaaaatttt attttctctc atatcgaata
    12241 tggccgaaaa ggccttaaaa aagaatatga aagagagatt gctgcacatc cagagcgaca
    12301 ttataagaag ccagaaaatt attcattatc aaatctattg tttcaatgga aagatactca
    12361 gaaaacattt ttcaataact ggctaactca agttaaaaaa agcaaattag tattattaga
    12421 taaataaaac gaggtataca ttatgtctat aatttataat tcagttacag aacttatcgg
    12481 caacactcca ttacttaagt tgaatcgcgt tgtacctgac gacgcggcag atgtctatgt
    12541 aaagttagaa tttgaaaacc cagctggttc aattaaagac agaattgctt tagctatgat
    12601 cgaaaaagct gaacgtgaag gcaacctaaa gccaggtggc acaattgtag aacctacttc
    12661 aggcaatacc ggtatcggtt tagccatggt tgctgcagct aaggactatc acattattat
    12721 tgttatgcca gaaactatga gcgttgagcg gcgtaaatta atgaagggct atggtgctga
    12781 acttattttg acaccaggtg cagacggtat gaagggttca attgctaagg ccgaagaatt
    12841 agttaaagag aaaggctact tcatgccaat gcaatttgaa aatacagaaa atcctaatat
    12901 tcatgaatta actactggtc cagaaattat tgccgcaatg aatggtatcg gcaaatccgt
    12961 tgatgccttt gttgctggtg ttggtactgg tggtacttta tcaggaattg gacatgcact
    13021 taggcgtgaa aatccatcca ctaagatatt tgcacttgag ccaactgaat ctccactctt
    13081 aaaagatgga aaaacaggta aacatggtat ccaaggtatt gccgcaggtt tcatccctaa
    13141 gaatttagat aaggatatct acgatgatat aattacagtt tctactgatg aagcaatggc
    13201 tacagctcgt gaagtagcta aaaacgaagg cttcttacct ggtatttcag ctggtgcaaa
    13261 catccatggt gcaatcgaaa ttgctaaaaa gttaggcaag ggacatgctg tggttactgt
    13321 agttccagac ggcggtgatc gttacctttc aactgcatta tttaatgctt aaaacttaat
    13381 ttctgtaaac aaatactcct aagtaaaatt tccttaggag tattattttt atttctgttg
    13441 attgtgcacc agtcaatgtt ggtacaacac ttttagtata atgaccttta ctaattagat
    13501 caatattgaa tttatttaag caccatgata ttgcactaag ctgtaaatat caacatcagg
    13561 caacttttct ctacccttta aatcaggcaa ttcaatgtaa aatgcagcac ctacaagctt
    13621 accaccaaga ttttcaatta attccttaga agctcttaaa gtacctgcag tagccattaa
    13681 atcgtcacag agaacaactc tttggccagg cttaattgca tctttatgca tttcaaggct
    13741 atttgaaccg tattccaagt catatgaagc acgttcaact tctcttggca acttatgtgg
    13801 ctttcttgct ggaacaaaac ctaagcctaa ctcagttgca acaggacagc ctacaataaa
    13861 gccacgtgct tcaggaccta cgattacatc tgcctttcta ctctttgcat attctgccaa
    13921 ttcatgagta gcaatacgat acaattcacc atcttgcaaa ataggtgtaa tatcgcgaaa
    13981 gacaattccc ttattaggaa agtccttaac acttgcaata tatttactaa aatcaatcgc
    14041 cataagaaga aaaacctcca taattctgtg cgtttgtatt caaacacttt tgacttgtat
    14101 attttaccaa agatttgtta taaaagtact gaaatcttga tatttatcta tctttttacc
    14161 aaattattaa catatgtaat taatttttga gtaggcatcg ttcttagttg attaataaat
    14221 ttaatttgtg aactcgttgc cattaaatat ttagaagctg tcaatggttg cttctttgga
    14281 ttagactcac caactaattt ttgatcgtct aatttaacaa aacctaattc aaagaatact
    14341 cgcaaaataa acaatacact atcataatcc aaacctagat atggtgctac agtgcgatag
    14401 tcttcaggct ttaatgctgg atgggcataa atatacttta acacttttcc gaaataactc
    14461 tttgctggaa tttgttcaac aggtaactga tctaataaaa agcataaata aatttgttga
    14521 taatcttttt ttaaagctgc atttaattcc acttgattgc gaggcacatc aagcaaagct
    14581 actgtttcac ccgattgatc ataatcttta accaagctaa ttttatcatc atcaatttga
    14641 aggctattct taacaattgg aatattcttt ttgtcaaaaa gcaaataacg atctgcaagg
    14701 cccatgacaa atttctcttg tcttaaatca attactgatg ttggcacagc taattttggg
    14761 gatgcaaagg ctattccttc catgatgcct tgcaaagata cttgtttgcg ataagtattc
    14821 aaagagagag taacaaagat ttttgaaata aatggtaaca aattattatt caaataatcc
    14881 ttattaaatc ccacaattgc taaattgccg tcttttttat tagctattaa tttaacatga
    14941 ttcttatctt ttcctatttt gaaaaagtgt gtaatagttg gatccgaaat actaaaaatt
    15001 ggctgcggat caccagtacc aaatggtccc acttgattaa tttgagccaa agtttgaggt
    15061 gataagtcat gcataggcaa ttccatatcg tactctttag tctctaaacc accgtcaaca
    15121 tgaaaatcgg cttcaaactt tttccgtagg tcatttactt tgtcttcttc catggataaa
    15181 ccacaagcaa aatcatgacc tccaaatttg gtcaatagac tttcttttaa cggattaaga
    15241 gcatcaaata agttaaaacc actgaatgaa cgacctgatc ccttaatctc cccttcatcg
    15301 tttttagtta aaacaattgt tggtttatgc agtttttcca ctatcttgtt agcaacaagc
    15361 cccaaaactc cttcatgaaa atcaggatca tataaaacta aagtattttg cttttgccaa
    15421 ctattttcac gaactaattc catgcagcga tcgtaaacct cagtagttag ctctttacgc
    15481 ttattattta agtcttcaat ctgatctgcg atcttctgtg cctcaagatc atcatcacta
    15541 agcaaaagct ctactgccag attagcatta gccaaacgtc caacagcatt aagtctagga
    15601 gcaatattaa agcctacatc tgtctcatta atcgtttcta gcgttaaacc ggcatttttg
    15661 ataagcgctc ttaagcccgg tcgttcggtt tgattaagaa catctaaccc acgttttaca
    15721 ataatatggc cttcaccagt aactttaacc atgtcaccaa tagtaccgat cattgctaaa
    15781 tctagcaatt ctggtacagg atcctgcata agctcacgac aaattgtata agctacacct
    15841 gcaccacaat aatcatcaaa aggatattct tgaccaggat aattacagtg aacaattgca
    15901 taagcatctg gcttattttc ttgaaaagta tggtgatccg taataatagt atcaacgcca
    15961 tgttctttag cgtattcaac ttcttcaa
//
