## Fri May 2 03:52:39 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_025191625.1/GCA_025191625.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_025191625.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_025191625.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs CCPPCCOK_00001 334390.LAF_1725 5.46e-161 451.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,3F43N@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A CCPPCCOK_00002 575594.ACOH01000003_gene684 1.36e-154 456.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,3F4IJ@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N CCPPCCOK_00003 334390.LAF_1201 6.47e-213 588.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,3F4PJ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh CCPPCCOK_00004 334390.LAF_1202 0.0 2036.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS CCPPCCOK_00005 334390.LAF_1203 7.25e-265 724.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase CCPPCCOK_00006 334390.LAF_1204 8.96e-310 844.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,3F3S3@33958|Lactobacillaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 CCPPCCOK_00007 334390.LAF_1205 1.33e-229 632.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,3F4BQ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N CCPPCCOK_00008 1045004.OKIT_1235 1.82e-73 227.0 COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,4HCWD@91061|Bacilli,4AYG4@81850|Leuconostocaceae 91061|Bacilli S Protein of unknown function (DUF1445) ycsI - - - - - - - - - - - DUF1445 CCPPCCOK_00010 1423806.JCM15457_1839 2.09e-100 303.0 COG0847@1|root,COG0847@2|Bacteria,1V0CE@1239|Firmicutes,4HVSS@91061|Bacilli,3F4RJ@33958|Lactobacillaceae 91061|Bacilli L CRISPR-associated protein (Cas_Cas2CT1978) cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - Cas_Cas2CT1978,RNase_T CCPPCCOK_00011 748671.LCRIS_01208 5.09e-159 453.0 COG1518@1|root,COG1518@2|Bacteria,1TQ6F@1239|Firmicutes,4HU4Z@91061|Bacilli,3F5DG@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1 CCPPCCOK_00012 1423806.JCM15457_1837 2.37e-90 271.0 2DKU6@1|root,30BEK@2|Bacteria,1V5I4@1239|Firmicutes,4HWF1@91061|Bacilli,3F5AF@33958|Lactobacillaceae 91061|Bacilli S CRISPR_assoc casE - - ko:K19126 - - - - ko00000,ko02048 - - - CRISPR_assoc CCPPCCOK_00013 944562.HMPREF9102_1221 7.03e-83 254.0 2DBXF@1|root,2ZBPB@2|Bacteria,1V2K8@1239|Firmicutes,4HX6U@91061|Bacilli,3F68A@33958|Lactobacillaceae 91061|Bacilli S CRISPR-associated protein (Cas_Cas5) casD - - ko:K19125 - - - - ko00000,ko02048 - - - Cas_Cas5d CCPPCCOK_00014 748671.LCRIS_01211 1.43e-162 466.0 COG1857@1|root,COG1857@2|Bacteria,1TSM0@1239|Firmicutes,4HTJZ@91061|Bacilli,3F3ZE@33958|Lactobacillaceae 91061|Bacilli L CT1975-like protein casC - - ko:K19124 - - - - ko00000,ko02048 - - - Cas_CT1975 CCPPCCOK_00015 908339.HMPREF9265_1251 2.42e-53 176.0 2CK1Q@1|root,32UPV@2|Bacteria,1VB3D@1239|Firmicutes,4HZ02@91061|Bacilli,3F6J5@33958|Lactobacillaceae 91061|Bacilli S CRISPR-associated protein Cse2 (CRISPR_cse2) - - - ko:K19046 - - - - ko00000,ko02048 - - - CRISPR_Cse2 CCPPCCOK_00016 1293597.BN147_04985 4.41e-176 516.0 COG1203@1|root,COG1203@2|Bacteria,1TSVP@1239|Firmicutes,4HUQ4@91061|Bacilli,3F55R@33958|Lactobacillaceae 91061|Bacilli L the current gene model (or a revised gene model) may contain a frame shift casA - - ko:K19123 - - - - ko00000,ko02048 - - - CRISPR_Cse1 CCPPCCOK_00017 714313.LSA_2p00290 0.0 1021.0 COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,4HAH7@91061|Bacilli,3F4VV@33958|Lactobacillaceae 91061|Bacilli L CRISPR-associated helicase cas3 cas3 - - ko:K07012 - - - - ko00000,ko01000,ko02048 - - - DEAD,Helicase_C CCPPCCOK_00018 334390.LAF_1219 6.59e-76 227.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,3F6K4@33958|Lactobacillaceae 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 CCPPCCOK_00019 334390.LAF_1220 0.0 912.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 CCPPCCOK_00020 334390.LAF_1221 2.22e-182 507.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,3F3NP@33958|Lactobacillaceae 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT CCPPCCOK_00021 334390.LAF_1222 1.52e-114 328.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,3F74P@33958|Lactobacillaceae 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM CCPPCCOK_00022 334390.LAF_1223 9.17e-54 168.0 COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,3F829@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 CCPPCCOK_00023 334390.LAF_1224 4.94e-58 179.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 CCPPCCOK_00024 334390.LAF_1225 2.78e-158 444.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,3F46W@33958|Lactobacillaceae 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU CCPPCCOK_00025 334390.LAF_1226 1.28e-176 492.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran CCPPCCOK_00026 334390.LAF_1227 1.74e-195 543.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,3F412@33958|Lactobacillaceae 91061|Bacilli P Phosphate transport system permease protein PstA pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 CCPPCCOK_00027 334390.LAF_1228 1.18e-196 547.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,3F3NI@33958|Lactobacillaceae 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 CCPPCCOK_00028 334390.LAF_1229 1.63e-204 566.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 CCPPCCOK_00029 334390.LAF_1230 7.18e-170 474.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,3F61A@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein, C-terminal domain protein - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CCPPCCOK_00030 334390.LAF_1231 1.89e-142 407.0 2AGCM@1|root,316IA@2|Bacteria,1U7XR@1239|Firmicutes,4IHV5@91061|Bacilli,3FAAW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00032 334390.LAF_1234 0.0 896.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,3F40R@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB CCPPCCOK_00033 334390.LAF_1235 1.72e-75 225.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,3F7FG@33958|Lactobacillaceae 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 CCPPCCOK_00034 334390.LAF_1236 5.57e-294 811.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,3F3YC@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N CCPPCCOK_00035 334390.LAF_1237 0.0 1908.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,3F478@33958|Lactobacillaceae 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge CCPPCCOK_00036 334390.LAF_1238 1.98e-166 465.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,3F564@33958|Lactobacillaceae 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm CCPPCCOK_00037 334390.LAF_1239 1.65e-47 152.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,3F7F4@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CCPPCCOK_00038 334390.LAF_1240 1.27e-214 596.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,3F4N9@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis CCPPCCOK_00039 334390.LAF_1241 0.0 1260.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,3F3JW@33958|Lactobacillaceae 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge CCPPCCOK_00040 334390.LAF_1242 0.0 1073.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,3F3X0@33958|Lactobacillaceae 91061|Bacilli S DAK2 domain fusion protein YloV yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 CCPPCCOK_00041 334390.LAF_1243 7.09e-76 227.0 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,3F72W@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function yloU - - - - - - - - - - - Asp23 CCPPCCOK_00042 334390.LAF_1244 5.82e-35 119.0 COG0227@1|root,COG0227@2|Bacteria,1TVQH@1239|Firmicutes,4HSV0@91061|Bacilli,3FCDR@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 CCPPCCOK_00043 334390.LAF_1245 3.05e-159 446.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,3F4N8@33958|Lactobacillaceae 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic CCPPCCOK_00044 334390.LAF_1246 1.1e-151 426.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3F4KX@33958|Lactobacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim CCPPCCOK_00045 334390.LAF_1247 8.84e-211 582.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,3F3XH@33958|Lactobacillaceae 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N CCPPCCOK_00046 334390.LAF_1248 0.0 1218.0 COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase CCPPCCOK_00047 334390.LAF_1249 1.68e-169 474.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,3F4UI@33958|Lactobacillaceae 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 CCPPCCOK_00048 334390.LAF_1250 5.57e-316 861.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,3F45F@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB CCPPCCOK_00049 334390.LAF_1251 5.61e-224 617.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,3F4N7@33958|Lactobacillaceae 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N CCPPCCOK_00050 334390.LAF_1252 0.0 1585.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,3F3N8@33958|Lactobacillaceae 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII CCPPCCOK_00051 334390.LAF_1253 5.94e-282 772.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,3F3XX@33958|Lactobacillaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein CCPPCCOK_00052 334390.LAF_1254 5.45e-61 187.0 COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,3F81N@33958|Lactobacillaceae 91061|Bacilli K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 CCPPCCOK_00053 334390.LAF_1255 1.03e-146 413.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,3F3X9@33958|Lactobacillaceae 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin CCPPCCOK_00055 334390.LAF_1257 0.0 1065.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,3F43U@33958|Lactobacillaceae 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N CCPPCCOK_00056 334390.LAF_1258 4.92e-99 288.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,3F71C@33958|Lactobacillaceae 91061|Bacilli K Regulates arginine biosynthesis genes argR2 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C CCPPCCOK_00057 334390.LAF_1259 1.14e-189 527.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,3F45T@33958|Lactobacillaceae 91061|Bacilli J Ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 CCPPCCOK_00058 334390.LAF_1260 3.42e-201 558.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,3F436@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt CCPPCCOK_00059 1203076.CAKF01000012_gene1146 1.64e-25 98.2 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes 1239|Firmicutes L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S CCPPCCOK_00060 334390.LAF_1262 0.0 910.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,3F4RE@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 CCPPCCOK_00061 334390.LAF_1263 2e-206 570.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,3F46A@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C CCPPCCOK_00062 334390.LAF_1264 9.82e-92 268.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,3F7KW@33958|Lactobacillaceae 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB CCPPCCOK_00063 334390.LAF_1265 2.1e-94 276.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,3F71X@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 CCPPCCOK_00064 334390.LAF_1266 3.44e-262 717.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,3F4DR@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 CCPPCCOK_00065 334390.LAF_1267 8.74e-62 189.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,3F6WU@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 CCPPCCOK_00066 334390.LAF_1268 1.2e-70 213.0 COG2868@1|root,COG2868@2|Bacteria,1VEQ9@1239|Firmicutes,4HNMV@91061|Bacilli,3F839@33958|Lactobacillaceae 91061|Bacilli J Cysteine protease Prp ysxB - - ko:K07584 - - - - ko00000 - - - Peptidase_Prp CCPPCCOK_00067 334390.LAF_1269 1.09e-66 202.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,3F6WT@33958|Lactobacillaceae 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p CCPPCCOK_00068 334390.LAF_1270 3.17e-149 420.0 COG1309@1|root,COG1309@2|Bacteria,1VGVA@1239|Firmicutes,4HPAG@91061|Bacilli,3F3TB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N CCPPCCOK_00070 334390.LAF_1271 1.1e-120 345.0 COG4508@1|root,COG4508@2|Bacteria,1VGAY@1239|Firmicutes,4HPDT@91061|Bacilli,3F6E4@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria - - - - - - - - - - - - dUTPase_2 CCPPCCOK_00071 334390.LAF_1272 5.75e-227 626.0 2F367@1|root,33W0S@2|Bacteria,1VK1W@1239|Firmicutes,4HWH4@91061|Bacilli,3F3MT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00072 334390.LAF_1273 1.9e-201 559.0 2AZ1J@1|root,31R7P@2|Bacteria,1V8SY@1239|Firmicutes,4HJRD@91061|Bacilli,3F4MX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00073 334390.LAF_1274 4.76e-19 77.8 29PWQ@1|root,30AV2@2|Bacteria,1U751@1239|Firmicutes,4IGZQ@91061|Bacilli,3F8ZI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00074 334390.LAF_1275 0.0 910.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,3F41A@33958|Lactobacillaceae 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N CCPPCCOK_00075 334390.LAF_1276 1.48e-219 605.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,3F3XS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT CCPPCCOK_00076 334390.LAF_1277 3.51e-33 114.0 2C91M@1|root,33E1E@2|Bacteria,1VPEZ@1239|Firmicutes,4HRR2@91061|Bacilli,3F8C0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3042) WQ51_02665 - - - - - - - - - - - DUF3042 CCPPCCOK_00077 334390.LAF_1278 4e-91 267.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,3F67E@33958|Lactobacillaceae 91061|Bacilli P Rhodanese-like protein yqhL - - - - - - - - - - - Rhodanese CCPPCCOK_00078 334390.LAF_1279 1.83e-231 637.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,3F4F0@33958|Lactobacillaceae 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK CCPPCCOK_00079 334390.LAF_1280 1.14e-48 155.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,3F83I@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF910) yqgQ - - - - - - - - - - - DUF910 CCPPCCOK_00080 334390.LAF_1281 1.68e-148 419.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,3F3WR@33958|Lactobacillaceae 91061|Bacilli S Peptidase, S54 family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 CCPPCCOK_00081 334390.LAF_1282 3.01e-126 359.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,3F4KQ@33958|Lactobacillaceae 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig CCPPCCOK_00082 334390.LAF_1283 7.58e-30 105.0 COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,3F828@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 CCPPCCOK_00083 334390.LAF_1284 0.0 1332.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,3F3KH@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase CCPPCCOK_00084 334390.LAF_1285 0.0 1720.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HBW6@91061|Bacilli,3F49G@33958|Lactobacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - YfhO CCPPCCOK_00085 334390.LAF_1286 1.81e-103 300.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,3F4ZF@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N CCPPCCOK_00086 334390.LAF_1287 6.9e-150 422.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,3F3KE@33958|Lactobacillaceae 91061|Bacilli F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK CCPPCCOK_00087 334390.LAF_1288 0.0 1595.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,3F3V3@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind CCPPCCOK_00088 334390.LAF_1289 2.58e-252 692.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,3F4NT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d CCPPCCOK_00089 334390.LAF_1290 1.44e-78 233.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,3F7FK@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family yodB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR CCPPCCOK_00090 334390.LAF_1291 4.08e-117 335.0 COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,4HHW0@91061|Bacilli,3F64N@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. XK27_09705 - - ko:K06950 - - - - ko00000 - - - HD CCPPCCOK_00091 334390.LAF_1292 1.84e-180 503.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,3F3NF@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind CCPPCCOK_00092 334390.LAF_1293 9.51e-61 186.0 COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli,3F81R@33958|Lactobacillaceae 91061|Bacilli C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020 Acylphosphatase CCPPCCOK_00093 334390.LAF_1294 1.13e-196 547.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,3F3P3@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP CCPPCCOK_00094 334390.LAF_1295 4.54e-91 266.0 COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,4HISW@91061|Bacilli,3F6ZA@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins def2 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase CCPPCCOK_00095 334390.LAF_1296 1.88e-298 816.0 COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,4IPM0@91061|Bacilli,3FBD2@33958|Lactobacillaceae 91061|Bacilli V MatE - - - - - - - - - - - - MatE CCPPCCOK_00096 334390.LAF_1297 0.0 969.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,3F3NU@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA CCPPCCOK_00097 334390.LAF_1298 1.38e-155 437.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,3F421@33958|Lactobacillaceae 91061|Bacilli K response regulator csrR - - - - - - - - - - - Response_reg,Trans_reg_C CCPPCCOK_00098 334390.LAF_1299 7.89e-38 126.0 COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli,3FCDY@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF GO:0003674,GO:0003735,GO:0005198 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p CCPPCCOK_00099 334390.LAF_1300 2.79e-126 359.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,3F61Z@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized ACR, COG1399 ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 CCPPCCOK_00100 334390.LAF_1301 2.38e-273 747.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,3F3QC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 CCPPCCOK_00101 334390.LAF_1302 7.76e-182 505.0 COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,4HD2W@91061|Bacilli,3F4KM@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase yqeM - - - - - - - - - - - Methyltransf_25 CCPPCCOK_00102 334390.LAF_1303 2.79e-77 230.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,3F7QN@33958|Lactobacillaceae 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS CCPPCCOK_00103 334390.LAF_1304 5.53e-145 408.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,3F47C@33958|Lactobacillaceae 91061|Bacilli H Hydrolase, HD family yqeK - - - - - - - - - - - HD CCPPCCOK_00104 334390.LAF_1305 1.62e-120 345.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,3F4D6@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like CCPPCCOK_00105 334390.LAF_1306 1.38e-65 199.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,3F7EW@33958|Lactobacillaceae 91061|Bacilli J RNA-binding protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY CCPPCCOK_00106 334390.LAF_1307 2.29e-275 752.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,3F4JU@33958|Lactobacillaceae 91061|Bacilli S Ribosome biogenesis GTPase YqeH yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 CCPPCCOK_00107 334390.LAF_1308 2.8e-124 354.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,3F46V@33958|Lactobacillaceae 91061|Bacilli S HAD phosphatase, family IIIA yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase CCPPCCOK_00108 1423758.BN55_07970 5.46e-33 122.0 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HM4F@91061|Bacilli,3F5F5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 CCPPCCOK_00109 387344.LVIS_1429 2.21e-22 94.7 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HM4F@91061|Bacilli,3F5F5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 CCPPCCOK_00110 334390.LAF_1309 4.67e-75 224.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,3F6HZ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 CCPPCCOK_00111 334390.LAF_1310 5.22e-37 124.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,3F7CQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p CCPPCCOK_00112 334390.LAF_1311 6.95e-111 319.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,3F4MS@33958|Lactobacillaceae 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N CCPPCCOK_00113 334390.LAF_1312 2.66e-221 610.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,3F4JK@33958|Lactobacillaceae 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 CCPPCCOK_00114 334390.LAF_1313 0.0 869.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,3F5D7@33958|Lactobacillaceae 91061|Bacilli L replication initiation and membrane attachment dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 CCPPCCOK_00115 334390.LAF_1314 3.44e-105 303.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,3F65S@33958|Lactobacillaceae 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone CCPPCCOK_00116 334390.LAF_1315 4.15e-137 389.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,3F6WF@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE CCPPCCOK_00117 334390.LAF_1316 6.22e-207 571.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS CCPPCCOK_00118 334390.LAF_1317 0.0 1713.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,3F3ZA@33958|Lactobacillaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A CCPPCCOK_00119 334390.LAF_1318 1.14e-178 497.0 COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,4HA7V@91061|Bacilli,3FB9J@33958|Lactobacillaceae 91061|Bacilli S Serine hydrolase (FSH1) yfhR3 - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4 CCPPCCOK_00120 334390.LAF_1319 1.24e-146 415.0 COG0670@1|root,COG0670@2|Bacteria,1V66F@1239|Firmicutes,4IR6X@91061|Bacilli,3FBMP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the BI1 family ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I CCPPCCOK_00121 334390.LAF_1320 0.0 865.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,3F49J@33958|Lactobacillaceae 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CCPPCCOK_00122 334390.LAF_1321 1.11e-152 428.0 COG0073@1|root,COG0073@2|Bacteria,1V3R1@1239|Firmicutes,4HHBI@91061|Bacilli,3F58U@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily ytpR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind CCPPCCOK_00123 334390.LAF_1322 1.53e-72 217.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,3F72K@33958|Lactobacillaceae 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin CCPPCCOK_00124 334390.LAF_1323 6.83e-76 226.0 COG5584@1|root,COG5584@2|Bacteria,1VMU8@1239|Firmicutes,4HREZ@91061|Bacilli,3F73X@33958|Lactobacillaceae 91061|Bacilli S Small secreted protein - - - - - - - - - - - - PepSY CCPPCCOK_00125 334390.LAF_1324 9.51e-161 449.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,3F3QM@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 CCPPCCOK_00126 334390.LAF_1325 5.42e-275 753.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,3F4HH@33958|Lactobacillaceae 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB CCPPCCOK_00127 334390.LAF_1326 3.02e-170 475.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,3F444@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CCPPCCOK_00128 334390.LAF_1327 4.29e-101 292.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,3F6K5@33958|Lactobacillaceae 91061|Bacilli FG histidine triad hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT CCPPCCOK_00130 334390.LAF_1329 6.67e-192 537.0 COG0760@1|root,COG0760@2|Bacteria,1V5RY@1239|Firmicutes,4HH41@91061|Bacilli,3FBHM@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Trigger_C CCPPCCOK_00131 334390.LAF_1330 2.59e-230 634.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,3F4SF@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon CCPPCCOK_00132 334390.LAF_1331 3.95e-73 220.0 COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HKKC@91061|Bacilli,3F822@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0342 family yheA - - - - - - - - - - - Com_YlbF CCPPCCOK_00133 334390.LAF_1332 0.0 1345.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F49Q@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase CCPPCCOK_00134 278197.PEPE_0507 3.62e-22 88.6 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein ytgB - - - - - - - - - - - Transgly_assoc CCPPCCOK_00135 1122149.BACN01000115_gene2 6.86e-60 184.0 COG2963@1|root,COG2963@2|Bacteria,1VCC9@1239|Firmicutes,4HS8E@91061|Bacilli,3F6ZZ@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 CCPPCCOK_00136 334390.LAF_1567 1.32e-09 58.5 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli,3F5JW@33958|Lactobacillaceae 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve CCPPCCOK_00137 334390.LAF_1544 6.19e-209 578.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3F4KJ@33958|Lactobacillaceae 91061|Bacilli P cation diffusion facilitator family transporter - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer CCPPCCOK_00138 334390.LAF_1545 2.17e-149 422.0 COG1814@1|root,COG1814@2|Bacteria,1V26W@1239|Firmicutes,4HGMW@91061|Bacilli,3F3TU@33958|Lactobacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - VIT1 CCPPCCOK_00139 334390.LAF_1546 5.26e-139 395.0 COG1814@1|root,COG1814@2|Bacteria,1V6KW@1239|Firmicutes,4HEC6@91061|Bacilli,3FBCU@33958|Lactobacillaceae 91061|Bacilli S VIT family - - - - - - - - - - - - VIT1 CCPPCCOK_00140 334390.LAF_1547 2.49e-110 317.0 COG0589@1|root,COG0589@2|Bacteria,1V8UY@1239|Firmicutes,4HK2J@91061|Bacilli,3F6N5@33958|Lactobacillaceae 91061|Bacilli T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp CCPPCCOK_00141 416269.APL_1504 1.18e-28 109.0 COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,1S9IF@1236|Gammaproteobacteria,1Y8M6@135625|Pasteurellales 135625|Pasteurellales S acyltransferase COG2153 elaA - - ko:K02348 - - - - ko00000 - - - Acetyltransf_10 CCPPCCOK_00142 334390.LAF_1548 4.6e-284 778.0 COG1266@1|root,COG1266@2|Bacteria,1VNA9@1239|Firmicutes,4HRMP@91061|Bacilli,3F5T9@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi CCPPCCOK_00143 334390.LAF_1549 0.0 1208.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3TT@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL CCPPCCOK_00144 334390.LAF_1550 1.15e-77 231.0 29PSZ@1|root,30AM0@2|Bacteria,1U6UA@1239|Firmicutes,4IGN4@91061|Bacilli,3F8HW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00145 334390.LAF_1551 3.98e-96 281.0 COG0789@1|root,COG0789@2|Bacteria,1VDPP@1239|Firmicutes,4HPJY@91061|Bacilli,3F6MS@33958|Lactobacillaceae 91061|Bacilli K MerR HTH family regulatory protein - - - - - - - - - - - - MerR_1 CCPPCCOK_00146 334390.LAF_1552 0.0 920.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 CCPPCCOK_00147 334390.LAF_1553 4.73e-150 424.0 2C9UQ@1|root,32RPZ@2|Bacteria,1VDDQ@1239|Firmicutes,4HNJB@91061|Bacilli,3F5X9@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4811) - - - - - - - - - - - - DUF4811 CCPPCCOK_00148 334390.LAF_1554 1.74e-187 529.0 COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,4HAWS@91061|Bacilli,3F4PN@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the conversion of L-arabinose to L-ribulose araA - 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 - R01761 RC00516 ko00000,ko00001,ko01000 - - - Arabinose_Iso_C,Arabinose_Isome CCPPCCOK_00149 334390.LAF_1559 2.46e-216 596.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F46Z@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 CCPPCCOK_00151 334390.LAF_1560 0.0 1663.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli,3F3PY@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM CCPPCCOK_00152 334390.LAF_1561 7.04e-139 392.0 COG0693@1|root,COG0693@2|Bacteria,1V3UV@1239|Firmicutes,4IQYM@91061|Bacilli,3F3T7@33958|Lactobacillaceae 91061|Bacilli S DJ-1/PfpI family - - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI CCPPCCOK_00153 334390.LAF_1562 3.88e-241 662.0 COG0657@1|root,COG0657@2|Bacteria,1V1HV@1239|Firmicutes,4HE9T@91061|Bacilli,3F5YJ@33958|Lactobacillaceae 91061|Bacilli I Alpha beta - - - - - - - - - - - - Abhydrolase_3 CCPPCCOK_00154 334390.LAF_1563 6.93e-155 435.0 COG1573@1|root,COG1573@2|Bacteria,1V4M9@1239|Firmicutes,4HMW1@91061|Bacilli,3FB9B@33958|Lactobacillaceae 91061|Bacilli L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG CCPPCCOK_00155 334390.LAF_1564 5.42e-286 783.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,4HU4D@91061|Bacilli,3F4FR@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE,ThrE_2 CCPPCCOK_00156 334390.LAF_1564 1.36e-20 89.4 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,4HU4D@91061|Bacilli,3F4FR@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE,ThrE_2 CCPPCCOK_00157 334390.LAF_1565 2.63e-208 576.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HB94@91061|Bacilli,3FC6N@33958|Lactobacillaceae 91061|Bacilli K LysR family transcriptional regulator mleR2 - - - - - - - - - - - HTH_1,LysR_substrate CCPPCCOK_00158 908339.HMPREF9265_1022 6.37e-187 519.0 COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,4HMJ7@91061|Bacilli,3F4FI@33958|Lactobacillaceae 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 CCPPCCOK_00159 908339.HMPREF9265_1023 0.0 886.0 COG1767@1|root,COG3697@1|root,COG1767@2|Bacteria,COG3697@2|Bacteria,1TQGQ@1239|Firmicutes,4HGCS@91061|Bacilli,3F4SU@33958|Lactobacillaceae 91061|Bacilli H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase citG - 2.4.2.52 ko:K05966 ko02020,map02020 - R09675 RC00049,RC00063 ko00000,ko00001,ko01000 - - - CitG,CitX CCPPCCOK_00160 908339.HMPREF9265_1024 0.0 990.0 COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,4HAE1@91061|Bacilli,3F4EA@33958|Lactobacillaceae 91061|Bacilli H Citrate (pro-3S)-lyase alpha chain citF - 2.8.3.10 ko:K01643 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - CitF CCPPCCOK_00161 908339.HMPREF9265_1025 7.54e-210 580.0 COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,4HD40@91061|Bacilli,3F47Q@33958|Lactobacillaceae 91061|Bacilli G Belongs to the HpcH HpaI aldolase family citE - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI CCPPCCOK_00162 908339.HMPREF9265_1026 3.36e-61 188.0 COG3052@1|root,COG3052@2|Bacteria,1VEZZ@1239|Firmicutes,4HNXD@91061|Bacilli,3F7FR@33958|Lactobacillaceae 91061|Bacilli C Covalent carrier of the coenzyme of citrate lyase citD - - ko:K01646 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001 - - - ACP CCPPCCOK_00163 908339.HMPREF9265_1027 3.24e-250 686.0 COG3053@1|root,COG3053@2|Bacteria,1TSGQ@1239|Firmicutes,4HC6Q@91061|Bacilli,3F4H7@33958|Lactobacillaceae 91061|Bacilli H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase citC - 6.2.1.22 ko:K01910 ko02020,map02020 - R04449 RC00012,RC00039 ko00000,ko00001,ko01000 - - - Acetyltransf_10,Citrate_ly_lig CCPPCCOK_00164 908339.HMPREF9265_1028 1.47e-267 733.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,3F4GN@33958|Lactobacillaceae 91061|Bacilli C Malic enzyme, NAD binding domain mae - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic CCPPCCOK_00165 908339.HMPREF9265_1029 1.49e-223 616.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,3F4PP@33958|Lactobacillaceae 91061|Bacilli K sugar-binding domain protein citR - - - - - - - - - - - Sugar-bind CCPPCCOK_00166 944562.HMPREF9102_1360 6.12e-312 853.0 COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,3F4RH@33958|Lactobacillaceae 91061|Bacilli P Sodium:sulfate symporter transmembrane region citP - - ko:K03319 - - - - ko00000 2.A.47 - - Na_sulph_symp CCPPCCOK_00167 908339.HMPREF9265_1031 4.87e-212 588.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N CCPPCCOK_00168 944562.HMPREF9102_1362 1.1e-275 761.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,3F3KJ@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain frdA - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2 CCPPCCOK_00169 525309.HMPREF0494_0744 3.78e-282 777.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,3F3K0@33958|Lactobacillaceae 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 CCPPCCOK_00170 1203076.CAKF01000025_gene929 2.48e-117 338.0 COG0431@1|root,COG0431@2|Bacteria,1TT2S@1239|Firmicutes,4HBQI@91061|Bacilli,3F544@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red CCPPCCOK_00171 1203076.CAKF01000025_gene930 1.26e-232 651.0 COG0431@1|root,COG2461@1|root,COG0431@2|Bacteria,COG2461@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli,3F44U@33958|Lactobacillaceae 91061|Bacilli S reductase XK27_09615 - 1.5.1.36 ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 - R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 - - - FMN_red,PAS_10 CCPPCCOK_00172 525309.HMPREF0494_0743 7.62e-290 803.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4HBF1@91061|Bacilli,3F3RH@33958|Lactobacillaceae 91061|Bacilli C Malic enzyme mleS GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0030145,GO:0036094,GO:0043167,GO:0043169,GO:0043464,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 - R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 - - - Malic_M,malic CCPPCCOK_00173 575594.ACOH01000006_gene161 6.84e-100 301.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,3F5D2@33958|Lactobacillaceae 91061|Bacilli K LysR family mleR - - - - - - - - - - - HTH_1,LysR_substrate CCPPCCOK_00174 1122147.AUEH01000008_gene1565 2.41e-57 196.0 COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HGC2@91061|Bacilli,3F5CV@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 CCPPCCOK_00175 334390.LAF_1577 1.87e-139 394.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,3F3TI@33958|Lactobacillaceae 91061|Bacilli G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase CCPPCCOK_00176 334390.LAF_1578 0.0 1210.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system scrA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC CCPPCCOK_00177 334390.LAF_1579 1.37e-248 682.0 COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HVD8@91061|Bacilli,3F599@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding alcohol dehydrogenase family protein adh - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N_2 CCPPCCOK_00178 334390.LAF_1580 0.0 1014.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,3F4UD@33958|Lactobacillaceae 91061|Bacilli G invertase scrB - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N CCPPCCOK_00179 334390.LAF_1581 5.33e-235 652.0 COG4320@1|root,COG4320@2|Bacteria,1UCBA@1239|Firmicutes,4HBCI@91061|Bacilli,3F3JA@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2252) - - - ko:K13730 ko05100,map05100 - - - ko00000,ko00001 - - - DUF2252 CCPPCCOK_00180 334390.LAF_1581 3.17e-78 244.0 COG4320@1|root,COG4320@2|Bacteria,1UCBA@1239|Firmicutes,4HBCI@91061|Bacilli,3F3JA@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2252) - - - ko:K13730 ko05100,map05100 - - - ko00000,ko00001 - - - DUF2252 CCPPCCOK_00181 334390.LAF_1582 1.71e-211 585.0 COG0583@1|root,COG0583@2|Bacteria,1TT5B@1239|Firmicutes,4HK1M@91061|Bacilli,3F5CC@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CCPPCCOK_00182 334390.LAF_1583 2.72e-212 586.0 COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,4HDT2@91061|Bacilli,3F59Q@33958|Lactobacillaceae 91061|Bacilli S Polyphosphate nucleotide phosphotransferase, PPK2 family - - - - - - - - - - - - PPK2 CCPPCCOK_00183 334390.LAF_1584 5.32e-142 400.0 29PMW@1|root,30AK2@2|Bacteria,1U6T2@1239|Firmicutes,4IGKT@91061|Bacilli,3F8FW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00185 334390.LAF_1585 0.0 956.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HA0N@91061|Bacilli,3F4J0@33958|Lactobacillaceae 91061|Bacilli E Amino Acid potE - - - - - - - - - - - AA_permease_2 CCPPCCOK_00186 334390.LAF_1586 1.6e-218 603.0 COG2367@1|root,COG2367@2|Bacteria,1VBZ3@1239|Firmicutes,4HN99@91061|Bacilli,3F672@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase enzyme family - - - - - - - - - - - - Beta-lactamase2 CCPPCCOK_00187 334390.LAF_1587 1.72e-285 781.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,3F43S@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 CCPPCCOK_00188 334390.LAF_1588 7.4e-126 358.0 29P54@1|root,30A3B@2|Bacteria,1U64T@1239|Firmicutes,4IFUC@91061|Bacilli,3F71V@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00189 334390.LAF_1589 7.4e-254 695.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,3F3RC@33958|Lactobacillaceae 91061|Bacilli G Lactonase, 7-bladed beta-propeller pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase CCPPCCOK_00190 334390.LAF_1590 3.77e-139 393.0 COG0671@1|root,COG0671@2|Bacteria,1U506@1239|Firmicutes,4IES2@91061|Bacilli,3F3M2@33958|Lactobacillaceae 91061|Bacilli I PAP2 superfamily - - - - - - - - - - - - PAP2 CCPPCCOK_00191 334390.LAF_1591 5.37e-72 216.0 COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,4HKDQ@91061|Bacilli,3F7T0@33958|Lactobacillaceae 91061|Bacilli S MazG-like family - - - - - - - - - - - - MazG-like CCPPCCOK_00192 334390.LAF_1592 0.0 1974.0 COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII CCPPCCOK_00193 334390.LAF_1593 1.64e-94 275.0 COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,4HIP6@91061|Bacilli,3F6VA@33958|Lactobacillaceae 91061|Bacilli L NUDIX domain mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX CCPPCCOK_00194 334390.LAF_1594 1.89e-123 352.0 COG1309@1|root,COG1309@2|Bacteria,1VI1M@1239|Firmicutes,4HPZV@91061|Bacilli,3F530@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N CCPPCCOK_00195 334390.LAF_1595 0.0 880.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 CCPPCCOK_00199 334390.LAF_1599 8.11e-52 163.0 COG4892@1|root,COG4892@2|Bacteria,1V64Y@1239|Firmicutes,4HNUM@91061|Bacilli,3F812@33958|Lactobacillaceae 91061|Bacilli S Cytochrome B5 - - - - - - - - - - - - Cyt-b5 CCPPCCOK_00200 334390.LAF_1600 1.62e-115 330.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,3F4W2@33958|Lactobacillaceae 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS CCPPCCOK_00201 334390.LAF_1601 4.27e-274 749.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,3F49P@33958|Lactobacillaceae 91061|Bacilli E methionine synthase, vitamin-B12 independent metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CCPPCCOK_00202 944562.HMPREF9102_1013 3.54e-99 301.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,3F4DZ@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair - - - - - - - - - - - - HTH_38,rve CCPPCCOK_00203 334390.LAF_0346 2.55e-216 597.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3F4VD@33958|Lactobacillaceae 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP CCPPCCOK_00204 334390.LAF_0345 5.7e-199 550.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,3F5CA@33958|Lactobacillaceae 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to metA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS CCPPCCOK_00205 575594.ACOH01000010_gene1697 4.74e-166 471.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,3F411@33958|Lactobacillaceae 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 CCPPCCOK_00206 334390.LAF_0344 2.23e-101 293.0 COG1917@1|root,COG1917@2|Bacteria,1V3TP@1239|Firmicutes,4HWR6@91061|Bacilli,3FBIH@33958|Lactobacillaceae 91061|Bacilli S Cupin domain yphH - - - - - - - - - - - Cupin_2 CCPPCCOK_00207 334390.LAF_0343 1.25e-240 660.0 COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,3F455@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid ykpB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C CCPPCCOK_00208 334390.LAF_0342 6.24e-289 788.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,3F4TW@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CCPPCCOK_00209 334390.LAF_0341 1.06e-188 523.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,3F4ND@33958|Lactobacillaceae 91061|Bacilli S Carbon-nitrogen hydrolase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase CCPPCCOK_00210 334390.LAF_0340 7.64e-220 606.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,3F45A@33958|Lactobacillaceae 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CCPPCCOK_00211 334390.LAF_0339 2.61e-235 648.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,3F4C8@33958|Lactobacillaceae 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N CCPPCCOK_00212 334390.LAF_0338 5.33e-209 577.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,3F42N@33958|Lactobacillaceae 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT CCPPCCOK_00213 334390.LAF_0337 3.39e-227 626.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,3F3Z3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N CCPPCCOK_00214 334390.LAF_0336 4.15e-69 209.0 COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,4HNXP@91061|Bacilli,3F7IN@33958|Lactobacillaceae 91061|Bacilli S Mycobacterial 4 TMS phage holin, superfamily IV yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 CCPPCCOK_00215 334390.LAF_0335 1.97e-70 212.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HQZ8@91061|Bacilli,3F7XD@33958|Lactobacillaceae 91061|Bacilli KT PspC domain protein - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC CCPPCCOK_00216 334390.LAF_0334 2.5e-258 707.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,3F3SN@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 CCPPCCOK_00217 334390.LAF_0333 0.0 1544.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,3F4DH@33958|Lactobacillaceae 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW CCPPCCOK_00218 334390.LAF_0332 4.64e-124 353.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,3F40M@33958|Lactobacillaceae 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE CCPPCCOK_00219 334390.LAF_0331 2.15e-166 464.0 COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli,3F714@33958|Lactobacillaceae 91061|Bacilli S Competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran CCPPCCOK_00220 334390.LAF_0330 0.0 872.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli,3F3TQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII CCPPCCOK_00221 334390.LAF_0329 4e-147 414.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,3F3SQ@33958|Lactobacillaceae 91061|Bacilli S YigZ family yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 CCPPCCOK_00222 334390.LAF_0328 1.68e-49 157.0 29PH0@1|root,30AYE@2|Bacteria,1U79N@1239|Firmicutes,4IH4I@91061|Bacilli,3F95S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00223 334390.LAF_0327 0.0 1174.0 COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli,3F44Y@33958|Lactobacillaceae 91061|Bacilli E amino acid ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 CCPPCCOK_00224 334390.LAF_0326 0.0 1008.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,3F3MM@33958|Lactobacillaceae 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 CCPPCCOK_00225 334390.LAF_0325 1.15e-57 179.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,3F7CZ@33958|Lactobacillaceae 91061|Bacilli O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 CCPPCCOK_00226 334390.LAF_0324 8.05e-149 419.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,3F40G@33958|Lactobacillaceae 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N CCPPCCOK_00227 334390.LAF_0323 0.0 1245.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn CCPPCCOK_00228 334390.LAF_0322 1.04e-224 620.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,3F5HY@33958|Lactobacillaceae 91061|Bacilli H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 CCPPCCOK_00229 334390.LAF_0321 1.67e-117 337.0 COG1268@1|root,COG1268@2|Bacteria,1VAAD@1239|Firmicutes,4HI8T@91061|Bacilli,3F6YG@33958|Lactobacillaceae 91061|Bacilli S BioY family bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY CCPPCCOK_00230 334390.LAF_0320 1.27e-173 485.0 COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,3F4AQ@33958|Lactobacillaceae 91061|Bacilli I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CCPPCCOK_00231 334390.LAF_0319 2.69e-181 504.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,3F496@33958|Lactobacillaceae 91061|Bacilli I alpha subunit accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA CCPPCCOK_00232 334390.LAF_0318 2.25e-206 570.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,3F3T6@33958|Lactobacillaceae 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans CCPPCCOK_00233 334390.LAF_0317 0.0 911.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,3F3PT@33958|Lactobacillaceae 91061|Bacilli I Acetyl-CoA carboxylase biotin carboxylase subunit accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 CCPPCCOK_00234 334390.LAF_0316 1.61e-97 283.0 COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,3F5EE@33958|Lactobacillaceae 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA CCPPCCOK_00235 334390.LAF_0315 4.05e-93 273.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,3F7M1@33958|Lactobacillaceae 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl CCPPCCOK_00236 334390.LAF_0314 1.32e-291 796.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,3F51H@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CCPPCCOK_00237 334390.LAF_0313 2.19e-164 461.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,3F4RI@33958|Lactobacillaceae 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 CCPPCCOK_00238 334390.LAF_0312 1.86e-217 601.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,3F3W9@33958|Lactobacillaceae 91061|Bacilli I Malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 CCPPCCOK_00239 334390.LAF_0311 4.18e-46 149.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli,3F7ZJ@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CCPPCCOK_00240 334390.LAF_0310 2.18e-218 603.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,3F3XP@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CCPPCCOK_00241 334390.LAF_0309 5.36e-97 282.0 COG1846@1|root,COG1846@2|Bacteria,1VDIT@1239|Firmicutes,4HNFP@91061|Bacilli,3F6SX@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 CCPPCCOK_00242 334390.LAF_0308 3.83e-100 290.0 COG0764@1|root,COG0764@2|Bacteria,1V6RB@1239|Firmicutes,4HJS6@91061|Bacilli,3FCD4@33958|Lactobacillaceae 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA CCPPCCOK_00244 334390.LAF_0306 3.65e-250 686.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,3F4AX@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 CCPPCCOK_00245 334390.LAF_0305 5.55e-143 403.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,3F522@33958|Lactobacillaceae 91061|Bacilli K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 CCPPCCOK_00246 334390.LAF_0304 1.13e-166 466.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,3F3WV@33958|Lactobacillaceae 91061|Bacilli O Universal bacterial protein YeaZ yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 CCPPCCOK_00247 334390.LAF_0303 3.25e-274 749.0 COG0436@1|root,COG0436@2|Bacteria,1TQPD@1239|Firmicutes,4HE7P@91061|Bacilli,3F3PZ@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase arcT - - - - - - - - - - - Aminotran_1_2 CCPPCCOK_00248 334390.LAF_0302 6.88e-281 766.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,3F49P@33958|Lactobacillaceae 91061|Bacilli E methionine synthase, vitamin-B12 independent metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CCPPCCOK_00249 334390.LAF_0301 0.0 900.0 COG0531@1|root,COG0531@2|Bacteria,1TSSB@1239|Firmicutes,4HA92@91061|Bacilli,3F3P5@33958|Lactobacillaceae 91061|Bacilli E Arginine ornithine antiporter arcD - - ko:K03758 - - - - ko00000,ko02000 2.A.3.2 - - AA_permease_2 CCPPCCOK_00250 334390.LAF_0300 3.45e-305 830.0 COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,4HCMG@91061|Bacilli,3F4VJ@33958|Lactobacillaceae 91061|Bacilli E Arginine arcA - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf CCPPCCOK_00251 334390.LAF_0299 4.08e-218 602.0 COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,4H9QD@91061|Bacilli,3F3T4@33958|Lactobacillaceae 91061|Bacilli E Belongs to the carbamate kinase family arcC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - - AA_kinase CCPPCCOK_00252 334390.LAF_0298 2.08e-239 658.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,3F48K@33958|Lactobacillaceae 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N CCPPCCOK_00253 334390.LAF_0297 1.35e-203 563.0 COG2197@1|root,COG2197@2|Bacteria,1UHR2@1239|Firmicutes,4HIGR@91061|Bacilli,3F61D@33958|Lactobacillaceae 91061|Bacilli KT YcbB domain - - - ko:K07719 ko02020,map02020 M00518 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,YcbB CCPPCCOK_00254 334390.LAF_0296 8.55e-247 676.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd CCPPCCOK_00255 334390.LAF_0295 1.67e-221 611.0 COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,3F3SR@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA CCPPCCOK_00256 334390.LAF_0294 0.0 1467.0 COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4HA88@91061|Bacilli,3F3PE@33958|Lactobacillaceae 91061|Bacilli P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N CCPPCCOK_00257 334390.LAF_0293 0.0 965.0 COG0248@1|root,COG0248@2|Bacteria,1VT8Q@1239|Firmicutes,4HB84@91061|Bacilli,3F49N@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx3 - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA CCPPCCOK_00258 334390.LAF_0292 3.31e-188 521.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli,3F41B@33958|Lactobacillaceae 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE CCPPCCOK_00259 334390.LAF_0291 2.83e-202 560.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,3F4AI@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase CCPPCCOK_00260 334390.LAF_0290 2.47e-74 222.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,3F864@33958|Lactobacillaceae 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB CCPPCCOK_00261 334390.LAF_0289 5.8e-248 681.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,3F50D@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C CCPPCCOK_00262 334390.LAF_0288 2.25e-70 212.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,3F6VW@33958|Lactobacillaceae 91061|Bacilli S Cyclic-di-AMP receptor yaaQ - - - - - - - - - - - CdAMP_rec CCPPCCOK_00263 334390.LAF_0287 2.41e-149 420.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,3F4JR@33958|Lactobacillaceae 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin CCPPCCOK_00264 557436.Lreu_0329 2.06e-28 104.0 2DKQF@1|root,30ABA@2|Bacteria,1U6F9@1239|Firmicutes,4IG70@91061|Bacilli,3F7S7@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2508) - - - - - - - - - - - - DUF2508 CCPPCCOK_00265 334390.LAF_0285 6.48e-142 400.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,3F4JQ@33958|Lactobacillaceae 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 CCPPCCOK_00266 334390.LAF_0284 3.97e-60 186.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,3F7F3@33958|Lactobacillaceae 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd CCPPCCOK_00267 334390.LAF_0283 0.0 1090.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3F3P2@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 CCPPCCOK_00269 334390.LAF_0282 1.5e-112 324.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,3F6IS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam CCPPCCOK_00270 334390.LAF_0281 6.56e-48 152.0 COG0695@1|root,COG0695@2|Bacteria,1VE2N@1239|Firmicutes,4HSRX@91061|Bacilli,3FBRA@33958|Lactobacillaceae 91061|Bacilli O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin CCPPCCOK_00271 334390.LAF_0280 0.0 1445.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,3F3XG@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN CCPPCCOK_00272 334390.LAF_0279 8.93e-250 684.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,3F3P1@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm CCPPCCOK_00273 334390.LAF_0278 0.0 881.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans CCPPCCOK_00274 334390.LAF_0277 0.0 1707.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,3F3RN@33958|Lactobacillaceae 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH CCPPCCOK_00275 334390.LAF_0276 0.0 1142.0 COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4HAAB@91061|Bacilli,3F4PG@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC cydD - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran CCPPCCOK_00276 334390.LAF_0275 0.0 1111.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HAN0@91061|Bacilli,3F451@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD cydC GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran CCPPCCOK_00277 334390.LAF_0274 4.17e-237 652.0 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,3F40S@33958|Lactobacillaceae 91061|Bacilli C Cytochrome d ubiquinol oxidase subunit II cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iYO844.BSU38750 Cyt_bd_oxida_II CCPPCCOK_00278 334390.LAF_0273 0.0 940.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,3F4MJ@33958|Lactobacillaceae 91061|Bacilli C ubiquinol oxidase cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I CCPPCCOK_00279 334390.LAF_0272 8.24e-71 214.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,3F6YA@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N CCPPCCOK_00280 334390.LAF_0271 3.88e-107 310.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,3F4S4@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 CCPPCCOK_00281 334390.LAF_0270 3.15e-312 851.0 COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,4HBGT@91061|Bacilli,3F3YJ@33958|Lactobacillaceae 91061|Bacilli E amino acid steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 CCPPCCOK_00282 908339.HMPREF9265_1979 3.46e-106 315.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 CCPPCCOK_00283 334390.LAF_0743 1.02e-69 211.0 COG3759@1|root,COG3759@2|Bacteria,1VAVU@1239|Firmicutes,4HQHN@91061|Bacilli,3F7NA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 CCPPCCOK_00284 1235801.C822_00263 9.83e-78 240.0 COG4974@1|root,COG4974@2|Bacteria,1V98H@1239|Firmicutes,4HM0P@91061|Bacilli,3F5YH@33958|Lactobacillaceae 91061|Bacilli L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase CCPPCCOK_00285 1423743.JCM14108_3045 1.13e-100 300.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3F9XU@33958|Lactobacillaceae 91061|Bacilli D Cellulose biosynthesis protein BcsQ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 CCPPCCOK_00287 334390.LAF_0742 2.84e-240 659.0 COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,3F455@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C CCPPCCOK_00288 1302286.BAOT01000069_gene2184 4.26e-36 123.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,3F4DZ@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair - - - - - - - - - - - - HTH_38,rve CCPPCCOK_00289 1545702.LACWKB8_0766 8.73e-41 140.0 COG3279@1|root,COG3279@2|Bacteria,1U6J0@1239|Firmicutes,4IGBI@91061|Bacilli,3F80K@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR CCPPCCOK_00290 701521.PECL_1353 1.08e-45 153.0 2AH77@1|root,330UE@2|Bacteria,1VC1H@1239|Firmicutes,4HNZ6@91061|Bacilli,3FC0W@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 CCPPCCOK_00291 1122149.BACN01000049_gene170 5.74e-249 684.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve CCPPCCOK_00292 334390.LAF_1573 3.64e-160 449.0 28MIG@1|root,2ZAV8@2|Bacteria,1V2VJ@1239|Firmicutes,4HHCS@91061|Bacilli,3F7P0@33958|Lactobacillaceae 91061|Bacilli S EcsC protein family - - - - - - - - - - - - EcsC CCPPCCOK_00293 1246.JMEA01000023_gene791 2.54e-58 182.0 COG3316@1|root,COG3316@2|Bacteria,1TTKR@1239|Firmicutes,4HCB4@91061|Bacilli,4AXG2@81850|Leuconostocaceae 91061|Bacilli L DDE domain tnp1216 - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 CCPPCCOK_00294 438780.D2KRD8_9CAUD 2.35e-38 135.0 4QAPV@10239|Viruses,4QPC3@28883|Caudovirales,4QKMY@10699|Siphoviridae 10699|Siphoviridae S DNA binding - - - - - - - - - - - - - CCPPCCOK_00296 1122147.AUEH01000006_gene1798 2.78e-23 96.3 COG1974@1|root,COG1974@2|Bacteria,1VJV9@1239|Firmicutes,4HJXB@91061|Bacilli 91061|Bacilli K Helix-turn-helix - - - - - - - - - - - - HTH_3,Peptidase_S24 CCPPCCOK_00297 525309.HMPREF0494_1808 2.13e-31 115.0 COG2856@1|root,COG2856@2|Bacteria,1W1K0@1239|Firmicutes,4IGCD@91061|Bacilli,3F81Z@33958|Lactobacillaceae 91061|Bacilli E Zn peptidase - - - - - - - - - - - - Peptidase_M48,Peptidase_M78 CCPPCCOK_00300 334390.LAF_0658 5.71e-140 399.0 COG1226@1|root,COG1226@2|Bacteria,1V285@1239|Firmicutes,4I17E@91061|Bacilli,3F64X@33958|Lactobacillaceae 91061|Bacilli P Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2,SHOCT CCPPCCOK_00301 1605.Lani381_0418 3.94e-78 247.0 COG2337@1|root,COG2337@2|Bacteria,1VH9V@1239|Firmicutes,4HPMX@91061|Bacilli,3F8EG@33958|Lactobacillaceae 91061|Bacilli T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - - - - - - - - - - PemK_toxin CCPPCCOK_00302 947980.E9LUL0_9CAUD 1.53e-80 243.0 4QE6D@10239|Viruses,4QV9U@35237|dsDNA viruses no RNA stage,4QR0Q@28883|Caudovirales,4QMJS@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - CCPPCCOK_00303 334390.LAF_0657 5e-255 700.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family int3 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase CCPPCCOK_00305 334390.LAF_0656 1.65e-128 367.0 28UQM@1|root,2ZGUY@2|Bacteria,1W3AZ@1239|Firmicutes,4I0YM@91061|Bacilli,3F65Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00306 334390.LAF_0655 9.97e-103 297.0 COG3613@1|root,COG3613@2|Bacteria,1U5KZ@1239|Firmicutes,4IFBV@91061|Bacilli,3F74G@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr CCPPCCOK_00307 334390.LAF_0654 4.88e-236 649.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,3F4JE@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family fruR3 - - ko:K02529,ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CCPPCCOK_00309 1071400.LBUCD034_0161 2.61e-21 95.1 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,3F5ZF@33958|Lactobacillaceae 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N CCPPCCOK_00310 334390.LAF_0646 0.0 1082.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,3F5CH@33958|Lactobacillaceae 91061|Bacilli E Aluminium induced protein asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 CCPPCCOK_00311 334390.LAF_0642 2.24e-11 63.2 COG0110@1|root,COG0110@2|Bacteria,1UXZQ@1239|Firmicutes,4IFG4@91061|Bacilli,3F6EF@33958|Lactobacillaceae 91061|Bacilli S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep CCPPCCOK_00312 334390.LAF_0641 5.6e-153 433.0 COG1028@1|root,COG1028@2|Bacteria,1TSJI@1239|Firmicutes,4HG70@91061|Bacilli,3F5I6@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 CCPPCCOK_00314 334390.LAF_0639 3.52e-253 695.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4HC8K@91061|Bacilli,3F4E4@33958|Lactobacillaceae 91061|Bacilli C dehydrogenase gldA - 1.1.1.6 ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 - R01034,R10715,R10717 RC00029,RC00117,RC00670 ko00000,ko00001,ko01000 - - - Fe-ADH CCPPCCOK_00315 1423724.BAMM01000020_gene1796 3.49e-13 68.2 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli 91061|Bacilli K transcriptional - - - - - - - - - - - - HTH_19,HTH_3 CCPPCCOK_00316 334390.LAF_0638 1.56e-67 204.0 COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HMY5@91061|Bacilli,3F7IR@33958|Lactobacillaceae 91061|Bacilli S Sugar efflux transporter for intercellular exchange - - - - - - - - - - - - MtN3_slv CCPPCCOK_00317 334390.LAF_0637 1.75e-73 220.0 COG1359@1|root,COG1359@2|Bacteria,1VAH9@1239|Firmicutes,4IR6P@91061|Bacilli,3FBMM@33958|Lactobacillaceae 91061|Bacilli S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM CCPPCCOK_00318 334390.LAF_0636 3.03e-61 188.0 COG2350@1|root,COG2350@2|Bacteria,1U89D@1239|Firmicutes,4II7A@91061|Bacilli,3FAQG@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria - - - - - - - - - - - - - CCPPCCOK_00319 334390.LAF_0635 1.63e-127 362.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HIR3@91061|Bacilli,3F6XY@33958|Lactobacillaceae 91061|Bacilli S Flavodoxin-like fold ydeQ - - ko:K11748 - - - - ko00000,ko02000 2.A.37.1.2 - - Flavodoxin_2 CCPPCCOK_00320 334390.LAF_0634 1.44e-56 176.0 COG0789@1|root,COG0789@2|Bacteria 2|Bacteria K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - - - - - - - - - - DUF3967,MerR_1 CCPPCCOK_00321 334390.LAF_0633 6.41e-195 540.0 COG3971@1|root,COG3971@2|Bacteria,1TQVG@1239|Firmicutes,4HBMC@91061|Bacilli,3F515@33958|Lactobacillaceae 91061|Bacilli Q hydratase mhpD - - ko:K02509 ko00350,ko01120,map00350,map01120 - R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 - - - - CCPPCCOK_00322 334390.LAF_0632 3.19e-238 655.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HH0S@91061|Bacilli,3FB6C@33958|Lactobacillaceae 91061|Bacilli C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhA - 1.1.1.28 ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 M00651 R00704 RC00044 ko00000,ko00001,ko00002,ko01000,ko01504 - - - 2-Hacid_dh,2-Hacid_dh_C CCPPCCOK_00323 334390.LAF_0631 1.35e-80 239.0 2DMJ0@1|root,32RWW@2|Bacteria,1VCR0@1239|Firmicutes 1239|Firmicutes S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 CCPPCCOK_00324 334390.LAF_0630 2.41e-123 351.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,3F4DB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran CCPPCCOK_00325 334390.LAF_0629 0.0 1481.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,3F42C@33958|Lactobacillaceae 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C CCPPCCOK_00326 334390.LAF_0628 1.3e-199 553.0 COG0300@1|root,COG0300@2|Bacteria,1UG37@1239|Firmicutes,4HC7Y@91061|Bacilli,3FC9N@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family fabG - 1.1.1.100 ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short CCPPCCOK_00327 334390.LAF_0627 8.64e-225 619.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,3F4F1@33958|Lactobacillaceae 91061|Bacilli J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 CCPPCCOK_00328 334390.LAF_0626 9.56e-317 862.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,3F4ZA@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 CCPPCCOK_00329 334390.LAF_0625 0.0 1202.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,3F3MY@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N CCPPCCOK_00330 334390.LAF_0624 3.97e-174 486.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran CCPPCCOK_00332 334390.LAF_0622 1.84e-68 206.0 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,3F6WJ@33958|Lactobacillaceae 91061|Bacilli S mazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG CCPPCCOK_00333 334390.LAF_0621 5.34e-140 395.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,3F44G@33958|Lactobacillaceae 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 CCPPCCOK_00334 334390.LAF_0620 2.06e-297 811.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,3F41K@33958|Lactobacillaceae 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX CCPPCCOK_00335 334390.LAF_0619 1.15e-299 819.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,3F40B@33958|Lactobacillaceae 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N CCPPCCOK_00336 334390.LAF_0618 9.97e-288 785.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,3F3ZP@33958|Lactobacillaceae 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 CCPPCCOK_00337 334390.LAF_0617 1.15e-208 578.0 COG0457@1|root,COG0457@2|Bacteria,1VXFK@1239|Firmicutes,4HX6X@91061|Bacilli,3FBB5@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - - CCPPCCOK_00338 334390.LAF_0616 0.0 1166.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3U9@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL CCPPCCOK_00339 334390.LAF_0615 0.0 909.0 COG2918@1|root,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,3F506@33958|Lactobacillaceae 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshAB - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase CCPPCCOK_00340 334390.LAF_0614 7.11e-57 176.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,3F7DV@33958|Lactobacillaceae 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 CCPPCCOK_00341 334390.LAF_0613 2.9e-47 152.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,3F7D8@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p CCPPCCOK_00342 334390.LAF_0611 1.63e-236 651.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,3F3TP@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta CCPPCCOK_00343 334390.LAF_0610 0.0 1457.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,3F3VT@33958|Lactobacillaceae 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B CCPPCCOK_00344 334390.LAF_0609 8.66e-116 331.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,3F6BF@33958|Lactobacillaceae 91061|Bacilli F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 CCPPCCOK_00345 334390.LAF_0608 4.91e-126 362.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,3F7NP@33958|Lactobacillaceae 91061|Bacilli L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB CCPPCCOK_00346 334390.LAF_0607 1.38e-252 692.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,3F4KY@33958|Lactobacillaceae 91061|Bacilli T Belongs to the peptidase S16 family lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 CCPPCCOK_00347 334390.LAF_0606 2.51e-115 331.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,3F6YS@33958|Lactobacillaceae 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like CCPPCCOK_00348 334390.LAF_0605 3.65e-128 364.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,3F505@33958|Lactobacillaceae 91061|Bacilli L RNA methyltransferase, RsmD family rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 CCPPCCOK_00349 334390.LAF_0604 1.31e-63 194.0 COG4471@1|root,COG4471@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2129) ylbG - - - - - - - - - - - DUF2129 CCPPCCOK_00350 334390.LAF_0603 1.02e-277 760.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,3F4IK@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE CCPPCCOK_00351 334390.LAF_0602 0.0 1204.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,3F3UK@33958|Lactobacillaceae 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 CCPPCCOK_00352 334390.LAF_0601 1.61e-176 492.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,3F5BB@33958|Lactobacillaceae 91061|Bacilli G Belongs to the inositol monophosphatase superfamily suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P CCPPCCOK_00353 334390.LAF_0600 1.55e-65 199.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli,3F80A@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 CCPPCCOK_00354 334390.LAF_0599 1.22e-132 376.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,3F3YH@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase CCPPCCOK_00355 334390.LAF_0598 7.14e-97 282.0 2C389@1|root,2ZQCN@2|Bacteria,1VQPI@1239|Firmicutes,4I0G9@91061|Bacilli,3F79N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00356 334390.LAF_0597 2.53e-42 138.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,3F807@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 CCPPCCOK_00357 334390.LAF_0596 2.95e-239 657.0 COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,4HJ8D@91061|Bacilli,3FBKT@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic - - - - - - - - - - - - DAGK_cat CCPPCCOK_00358 334390.LAF_0595 2.39e-98 285.0 COG1393@1|root,COG1393@2|Bacteria,1TTEA@1239|Firmicutes,4I3R5@91061|Bacilli,3F6ZW@33958|Lactobacillaceae 91061|Bacilli P ArsC family - - - - - - - - - - - - ArsC CCPPCCOK_00359 334390.LAF_0594 3.81e-228 629.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HV42@91061|Bacilli,3FCBW@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs2 - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N CCPPCCOK_00360 334390.LAF_0593 0.0 1637.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F44X@33958|Lactobacillaceae 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 CCPPCCOK_00361 334390.LAF_0592 9.37e-159 445.0 COG0457@1|root,COG0457@2|Bacteria,1VFGR@1239|Firmicutes,4IBSH@91061|Bacilli,3F4MD@33958|Lactobacillaceae 91061|Bacilli S repeat protein - - - - - - - - - - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 CCPPCCOK_00362 334390.LAF_0591 6.4e-156 437.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F3U3@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase pgm6 - - - - - - - - - - - His_Phos_1 CCPPCCOK_00363 334390.LAF_0590 1.08e-218 603.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli,3F4M2@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily hdhL - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N CCPPCCOK_00364 334390.LAF_0589 0.0 1053.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4HC54@91061|Bacilli,3F4DW@33958|Lactobacillaceae 91061|Bacilli S amidohydrolase - - - - - - - - - - - - Amidohydro_3 CCPPCCOK_00365 1423755.BAML01000047_gene1603 1.92e-05 54.7 COG5295@1|root,COG5295@2|Bacteria,1VIS5@1239|Firmicutes,4HIVX@91061|Bacilli,3F567@33958|Lactobacillaceae 91061|Bacilli UW Tetratricopeptide repeat - - - - - - - - - - - - Gram_pos_anchor CCPPCCOK_00366 334390.LAF_1175 0.0 945.0 COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli,3F4UM@33958|Lactobacillaceae 91061|Bacilli J Belongs to the amidase family nylA - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase CCPPCCOK_00367 334390.LAF_1176 1.14e-163 462.0 COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,4H9P7@91061|Bacilli,3F4C3@33958|Lactobacillaceae 91061|Bacilli S C4-dicarboxylate anaerobic carrier arcD - - - - - - - - - - - DcuC CCPPCCOK_00368 334390.LAF_1177 4.48e-279 762.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,3F3NZ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 CCPPCCOK_00369 334390.LAF_1178 9.95e-108 310.0 COG1051@1|root,COG1051@2|Bacteria,1V6X2@1239|Firmicutes,4IQ2D@91061|Bacilli,3FBFE@33958|Lactobacillaceae 91061|Bacilli F Hydrolase, NUDIX family - - - - - - - - - - - - NUDIX CCPPCCOK_00370 334390.LAF_1179 1.1e-278 762.0 COG0433@1|root,COG0433@2|Bacteria,1UA9I@1239|Firmicutes,4HUCP@91061|Bacilli,3F409@33958|Lactobacillaceae 91061|Bacilli S AAA-like domain - - - ko:K06915 - - - - ko00000 - - - DUF853,DUF87,Zot CCPPCCOK_00371 334390.LAF_1180 1.04e-149 437.0 COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,4HAS9@91061|Bacilli,3F4B4@33958|Lactobacillaceae 91061|Bacilli J elongation factor G fusA1 - - - - - - - - - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU CCPPCCOK_00372 334390.LAF_1180 3.15e-294 813.0 COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,4HAS9@91061|Bacilli,3F4B4@33958|Lactobacillaceae 91061|Bacilli J elongation factor G fusA1 - - - - - - - - - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU CCPPCCOK_00373 334390.LAF_1181 2.08e-75 226.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,3F6VZ@33958|Lactobacillaceae 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA CCPPCCOK_00374 334390.LAF_1182 3.1e-144 406.0 COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,3F4MR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 CCPPCCOK_00375 334390.LAF_1183 2.42e-152 427.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,3F4DG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU CCPPCCOK_00376 334390.LAF_1184 0.0 1303.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F424@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein 1A ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 CCPPCCOK_00377 334390.LAF_1185 6.64e-205 568.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA CCPPCCOK_00378 334390.LAF_1186 1.41e-244 671.0 COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4HAZ2@91061|Bacilli,3F414@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase family protein tas3 - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red CCPPCCOK_00379 334390.LAF_1187 5.43e-190 533.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,3FBNF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1002) ypuA - - - - - - - - - - - DUF1002 CCPPCCOK_00380 334390.LAF_1188 4.14e-173 483.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,3F4FF@33958|Lactobacillaceae 91061|Bacilli L DnaD domain protein dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 CCPPCCOK_00381 334390.LAF_1189 0.0 887.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,3F4EK@33958|Lactobacillaceae 91061|Bacilli J Asparaginyl-tRNA synthetase asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon CCPPCCOK_00382 334390.LAF_1190 6.66e-115 330.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,3F4MM@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria ypmB - - - - - - - - - - - PepSY CCPPCCOK_00383 334390.LAF_1191 0.0 1825.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,3F4KA@33958|Lactobacillaceae 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII CCPPCCOK_00384 334390.LAF_1192 5.33e-215 594.0 COG1577@1|root,COG1577@2|Bacteria,1TT5C@1239|Firmicutes,4HAQQ@91061|Bacilli,3F3TW@33958|Lactobacillaceae 91061|Bacilli I mevalonate kinase mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CCPPCCOK_00385 334390.LAF_1193 7.43e-231 636.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli,3F4B5@33958|Lactobacillaceae 91061|Bacilli I diphosphomevalonate decarboxylase mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CCPPCCOK_00386 334390.LAF_1194 1e-271 743.0 COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HC93@91061|Bacilli,3F3RZ@33958|Lactobacillaceae 91061|Bacilli I phosphomevalonate kinase mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CCPPCCOK_00387 334390.LAF_1195 5.29e-263 720.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,3F3UY@33958|Lactobacillaceae 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh CCPPCCOK_00388 334390.LAF_1196 2.25e-118 350.0 COG1117@1|root,COG2826@1|root,COG1117@2|Bacteria,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,3F4DZ@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair - - - - - - - - - - - - HTH_38,rve CCPPCCOK_00389 334390.LAF_1058 1.77e-234 644.0 29NMY@1|root,309JW@2|Bacteria,1U58X@1239|Firmicutes,4IF08@91061|Bacilli,3F570@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00390 334390.LAF_1057 1.01e-99 289.0 2BZ0D@1|root,309UA@2|Bacteria,1U5Q9@1239|Firmicutes,4IFEF@91061|Bacilli,3F6B1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00391 334390.LAF_1055 7.8e-44 154.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaK - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger CCPPCCOK_00392 203120.LEUM_1744 2.77e-62 200.0 COG2910@1|root,COG2910@2|Bacteria,1V546@1239|Firmicutes,4IRQD@91061|Bacilli 91061|Bacilli S NAD(P)H-binding - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 CCPPCCOK_00393 334390.LAF_1054 0.0 1003.0 COG2918@1|root,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,3F506@33958|Lactobacillaceae 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase CCPPCCOK_00394 334390.LAF_1052 1.69e-124 354.0 COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,4HNUJ@91061|Bacilli,3F86G@33958|Lactobacillaceae 91061|Bacilli V VanZ like family - - - - - - - - - - - - VanZ CCPPCCOK_00395 334390.LAF_1051 2.95e-284 776.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CCPPCCOK_00396 334390.LAF_1050 1.59e-80 238.0 COG4841@1|root,COG4841@2|Bacteria,1U71X@1239|Firmicutes,4IGWD@91061|Bacilli,3F8VF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00397 334390.LAF_1049 1.39e-233 643.0 COG1609@1|root,COG1609@2|Bacteria,1TQSY@1239|Firmicutes,4HAJI@91061|Bacilli,3FC5E@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family - - - ko:K02525 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3,Peripla_BP_4 CCPPCCOK_00398 334390.LAF_1048 2.34e-301 824.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,3F3V0@33958|Lactobacillaceae 91061|Bacilli EG Gluconate gntP GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015128,GO:0015144,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease CCPPCCOK_00399 334390.LAF_1047 0.0 992.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N CCPPCCOK_00400 334390.LAF_1046 1.37e-218 603.0 COG1396@1|root,COG1396@2|Bacteria,1VD87@1239|Firmicutes,4HKR0@91061|Bacilli,3F7WI@33958|Lactobacillaceae 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family - - - ko:K20375 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - - CCPPCCOK_00401 334390.LAF_1045 1.02e-114 329.0 COG0474@1|root,COG0474@2|Bacteria 2|Bacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.6 ko:K01535 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase CCPPCCOK_00405 1231336.L248_1872 7.82e-121 361.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli 91061|Bacilli L DNA repair exonuclease yhaO - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 CCPPCCOK_00406 1231336.L248_1871 2.66e-177 544.0 COG0419@1|root,COG4717@1|root,COG0419@2|Bacteria,COG4717@2|Bacteria,1TQP3@1239|Firmicutes 1239|Firmicutes D Psort location Cytoplasmic, score - - - - - - - - - - - - AAA_23,AAA_27 CCPPCCOK_00407 334390.LAF_1632 1.29e-281 778.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,3FA2E@33958|Lactobacillaceae 91061|Bacilli HI 1-deoxy-D-xylulose-5-phosphate synthase - - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C CCPPCCOK_00408 334390.LAF_1635 5.1e-66 201.0 COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,4HKGZ@91061|Bacilli,3F6YC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0145 family ybjQ - - - - - - - - - - - YbjQ_1 CCPPCCOK_00409 1136177.KCA1_1516 1.13e-98 296.0 COG0010@1|root,COG0010@2|Bacteria,1V45X@1239|Firmicutes,4HU4J@91061|Bacilli,3F628@33958|Lactobacillaceae 91061|Bacilli E Arginase family - - 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase CCPPCCOK_00410 1136177.KCA1_1516 1.1e-07 52.4 COG0010@1|root,COG0010@2|Bacteria,1V45X@1239|Firmicutes,4HU4J@91061|Bacilli,3F628@33958|Lactobacillaceae 91061|Bacilli E Arginase family - - 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase CCPPCCOK_00411 334390.LAF_1637 1.48e-219 606.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,3F4PC@33958|Lactobacillaceae 91061|Bacilli S Nitronate monooxygenase - - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO CCPPCCOK_00412 334390.LAF_1638 6.7e-72 216.0 COG0640@1|root,COG0640@2|Bacteria,1V79H@1239|Firmicutes,4HIV4@91061|Bacilli,3F7XM@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_20 CCPPCCOK_00413 334390.LAF_1639 4.09e-136 385.0 29W71@1|root,30HS8@2|Bacteria,1VZSI@1239|Firmicutes 1239|Firmicutes S Domain of unknown function (DUF4767) - - - - - - - - - - - - DUF4767 CCPPCCOK_00414 334390.LAF_1641 3.05e-146 414.0 2ACE2@1|root,311ZJ@2|Bacteria,1U5CK@1239|Firmicutes,4IF3R@91061|Bacilli,3F5IZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4767 CCPPCCOK_00416 334390.LAF_1642 0.0 888.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli,3FC0Z@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus pacL - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 CCPPCCOK_00417 334390.LAF_1642 1.62e-252 716.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli,3FC0Z@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus pacL - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 CCPPCCOK_00418 334390.LAF_1643 0.0 1558.0 COG3256@1|root,COG3256@2|Bacteria,1TSW2@1239|Firmicutes,4HCFR@91061|Bacilli,3F4ID@33958|Lactobacillaceae 91061|Bacilli P Cytochrome C and Quinol oxidase polypeptide I - - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 CCPPCCOK_00419 349123.Lreu23DRAFT_4559 0.0 928.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,3F3NV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase CCPPCCOK_00420 334390.LAF_1644 1.16e-146 412.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4IQWD@91061|Bacilli,3F518@33958|Lactobacillaceae 91061|Bacilli T Region found in RelA / SpoT proteins - - - - - - - - - - - - RelA_SpoT CCPPCCOK_00421 1423806.JCM15457_1808 1.35e-100 298.0 COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,4HG2E@91061|Bacilli,3F53G@33958|Lactobacillaceae 91061|Bacilli K response regulator dltr - - - - - - - - - - - Response_reg,Trans_reg_C CCPPCCOK_00422 1423806.JCM15457_1809 2.55e-165 477.0 COG0642@1|root,COG0642@2|Bacteria,1UHQH@1239|Firmicutes,4HAHG@91061|Bacilli,3F4JY@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase sptS - - - - - - - - - - - HATPase_c,HisKA CCPPCCOK_00423 334390.LAF_1646 9.32e-223 613.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli,3F42Q@33958|Lactobacillaceae 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK CCPPCCOK_00424 334390.LAF_1647 6.6e-134 379.0 COG0454@1|root,COG0456@2|Bacteria,1VEW7@1239|Firmicutes,4HPE4@91061|Bacilli,3F5HK@33958|Lactobacillaceae 91061|Bacilli K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 CCPPCCOK_00425 334390.LAF_1648 1.05e-174 487.0 COG1028@1|root,COG1028@2|Bacteria,1TPHT@1239|Firmicutes,4HVYE@91061|Bacilli,3FC9Q@33958|Lactobacillaceae 91061|Bacilli IQ dehydrogenase reductase - - - - - - - - - - - - adh_short_C2 CCPPCCOK_00426 334390.LAF_1649 0.0 1375.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase CCPPCCOK_00427 334390.LAF_1650 1.53e-137 394.0 COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,4HDIE@91061|Bacilli,3F5JP@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA CCPPCCOK_00428 334390.LAF_1650 1.4e-40 142.0 COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,4HDIE@91061|Bacilli,3F5JP@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA CCPPCCOK_00429 334390.LAF_1651 0.0 1485.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase helD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 CCPPCCOK_00430 334390.LAF_1652 4.15e-152 427.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F51Q@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc CCPPCCOK_00431 334390.LAF_1653 1.92e-155 436.0 COG0406@1|root,COG0406@2|Bacteria,1TQWQ@1239|Firmicutes,4HFDZ@91061|Bacilli,3F5CT@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase pgm3 - - - - - - - - - - - His_Phos_1 CCPPCCOK_00432 334390.LAF_1654 2.06e-297 812.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,3F4B2@33958|Lactobacillaceae 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 CCPPCCOK_00433 334390.LAF_1655 3.6e-265 726.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HBMX@91061|Bacilli,3FB6U@33958|Lactobacillaceae 91061|Bacilli H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC - 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N CCPPCCOK_00434 334390.LAF_1656 2.05e-172 481.0 COG3201@1|root,COG3201@2|Bacteria,1UYDN@1239|Firmicutes,4HJE5@91061|Bacilli,3F469@33958|Lactobacillaceae 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter CCPPCCOK_00435 334390.LAF_1657 0.0 1027.0 COG0531@1|root,COG0531@2|Bacteria,1TPJH@1239|Firmicutes,4HUE6@91061|Bacilli,3FCAM@33958|Lactobacillaceae 91061|Bacilli E amino acid - - - - - - - - - - - - AA_permease_2 CCPPCCOK_00436 334390.LAF_0748 6.7e-81 241.0 2A5X0@1|root,30UP0@2|Bacteria,1U6DW@1239|Firmicutes,4IG5K@91061|Bacilli,3F7P8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00437 334390.LAF_0749 1.16e-242 667.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,3F3ST@33958|Lactobacillaceae 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg CCPPCCOK_00438 334390.LAF_0750 2.79e-86 259.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,3F4DY@33958|Lactobacillaceae 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE CCPPCCOK_00439 334390.LAF_0751 0.0 1174.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,3F48C@33958|Lactobacillaceae 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 CCPPCCOK_00440 334390.LAF_0752 3.33e-265 728.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,3F490@33958|Lactobacillaceae 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG CCPPCCOK_00441 334390.LAF_0753 1.46e-71 218.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HHNQ@91061|Bacilli,3F5AD@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase CCPPCCOK_00442 334390.LAF_0761 2.15e-11 63.5 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,3F3XV@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth CCPPCCOK_00443 334390.LAF_0761 7.26e-130 372.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,3F3XV@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth CCPPCCOK_00444 334390.LAF_0762 4.55e-74 221.0 COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,3F73W@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH CCPPCCOK_00445 334390.LAF_0763 2.63e-69 209.0 COG0140@1|root,COG0140@2|Bacteria,1VB6S@1239|Firmicutes,4HKDY@91061|Bacilli,3F7V5@33958|Lactobacillaceae 91061|Bacilli E phosphoribosyl-ATP diphosphatase activity hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH CCPPCCOK_00446 334390.LAF_0764 7.73e-256 702.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,3F466@33958|Lactobacillaceae 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CCPPCCOK_00447 334390.LAF_0765 0.0 1194.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,3F3Z1@33958|Lactobacillaceae 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C CCPPCCOK_00449 334390.LAF_0767 3.72e-145 409.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F5SD@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase pgm1 - - - - - - - - - - - His_Phos_1 CCPPCCOK_00450 484018.BACPLE_02599 2.83e-140 407.0 COG0667@1|root,COG0667@2|Bacteria,4NKHD@976|Bacteroidetes,2FQ6I@200643|Bacteroidia,4AQAA@815|Bacteroidaceae 976|Bacteroidetes C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red CCPPCCOK_00451 334390.LAF_0768 5.06e-259 709.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,3F4IU@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 CCPPCCOK_00452 334390.LAF_0769 1.2e-281 769.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,3F4JJ@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT_4 CCPPCCOK_00453 334390.LAF_0770 0.0 924.0 COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,4HAQT@91061|Bacilli,3F4Q7@33958|Lactobacillaceae 91061|Bacilli K COG COG0846 NAD-dependent protein deacetylases, SIR2 family - - - - - - - - - - - - SIR2 CCPPCCOK_00454 334390.LAF_0772 2.35e-104 301.0 COG1959@1|root,COG1959@2|Bacteria 2|Bacteria K 2 iron, 2 sulfur cluster binding - - - - - - - - - - - - Rrf2 CCPPCCOK_00455 334390.LAF_0773 1.97e-106 307.0 COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,3F70X@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08940 DMRL_synthase CCPPCCOK_00456 334390.LAF_0774 4.58e-289 789.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,3F4EB@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08945 DHBP_synthase,GTP_cyclohydro2 CCPPCCOK_00457 334390.LAF_0775 6.44e-139 393.0 COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,3F6M0@33958|Lactobacillaceae 91061|Bacilli H Riboflavin synthase ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08950,iYO844.BSU23270 Lum_binding CCPPCCOK_00458 334390.LAF_0776 3.99e-258 707.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,3F4X5@33958|Lactobacillaceae 91061|Bacilli H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 CCPPCCOK_00459 334390.LAF_0777 2.01e-70 214.0 COG0716@1|root,COG0716@2|Bacteria 2|Bacteria C FMN binding - - - - - - - - - - - - Flavodoxin_4 CCPPCCOK_00460 1121914.AUDW01000024_gene106 1.04e-77 249.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HB4P@91061|Bacilli,3WFND@539002|Bacillales incertae sedis 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA CCPPCCOK_00461 1121914.AUDW01000024_gene105 3.89e-19 84.0 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HGB5@91061|Bacilli,3WFJH@539002|Bacillales incertae sedis 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C CCPPCCOK_00462 334390.LAF_1333 0.0 1108.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,3F4DE@33958|Lactobacillaceae 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d CCPPCCOK_00464 334390.LAF_1335 4.86e-53 169.0 2DKPT@1|root,30A91@2|Bacteria,1U6CF@1239|Firmicutes,4IG44@91061|Bacilli,3F7KP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2187 CCPPCCOK_00466 334390.LAF_1336 1.48e-257 707.0 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,3F4SS@33958|Lactobacillaceae 91061|Bacilli H dihydropteroate synthase folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind CCPPCCOK_00467 334390.LAF_1337 5.55e-137 387.0 COG0127@1|root,COG0127@2|Bacteria,1VWAB@1239|Firmicutes,4HWPY@91061|Bacilli,3F4R5@33958|Lactobacillaceae 91061|Bacilli F Ham1 family folQ - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like CCPPCCOK_00468 334390.LAF_1338 6.78e-308 839.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,3F3ZR@33958|Lactobacillaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M CCPPCCOK_00469 334390.LAF_1339 3.93e-134 380.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,3F4A0@33958|Lactobacillaceae 91061|Bacilli F GTP cyclohydrolase 1 folE - 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI,HPPK CCPPCCOK_00470 334390.LAF_1340 3.88e-123 350.0 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,3F6SY@33958|Lactobacillaceae 91061|Bacilli H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK CCPPCCOK_00471 334390.LAF_1341 9.96e-82 242.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli,3F7N6@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB CCPPCCOK_00472 334390.LAF_1342 5.83e-152 428.0 COG1266@1|root,COG1266@2|Bacteria,1VFRX@1239|Firmicutes,4HRQQ@91061|Bacilli,3F4Q0@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity XK27_07085 - - ko:K07052 - - - - ko00000 - - - Abi CCPPCCOK_00473 334390.LAF_1343 7.46e-234 644.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4HE07@91061|Bacilli,3F44Q@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family rbsR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 CCPPCCOK_00474 334390.LAF_1344 9.92e-143 402.0 29NQX@1|root,309NV@2|Bacteria,1U5EA@1239|Firmicutes,4IF5Q@91061|Bacilli,3F5Q3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00475 334390.LAF_1345 3.06e-150 422.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F4MY@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase dgk2 - - - - - - - - - - - dNK CCPPCCOK_00476 334390.LAF_1346 4.64e-240 663.0 COG1705@1|root,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HVMB@91061|Bacilli,3FC1U@33958|Lactobacillaceae 91061|Bacilli NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - - - - - - - - - - Glucosaminidase CCPPCCOK_00477 334390.LAF_1347 0.0 896.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli,3F3QW@33958|Lactobacillaceae 91061|Bacilli S Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_4,YkuD CCPPCCOK_00478 334390.LAF_1348 1.65e-112 323.0 COG0589@1|root,COG0589@2|Bacteria,1VMC9@1239|Firmicutes,4HYXY@91061|Bacilli,3F6UZ@33958|Lactobacillaceae 91061|Bacilli T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp CCPPCCOK_00479 334390.LAF_1349 0.0 934.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,3F3UV@33958|Lactobacillaceae 91061|Bacilli E dipeptidase PepV pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CCPPCCOK_00480 334390.LAF_1350 9.4e-199 551.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,3F480@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N CCPPCCOK_00481 334390.LAF_1351 4.9e-83 245.0 COG3439@1|root,COG3439@2|Bacteria,1VPXG@1239|Firmicutes,4HRCS@91061|Bacilli 91061|Bacilli S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 CCPPCCOK_00482 334390.LAF_1352 0.0 1030.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,3F404@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C CCPPCCOK_00483 334390.LAF_1353 9.88e-57 176.0 28VX1@1|root,30AJ1@2|Bacteria,1U6RI@1239|Firmicutes,4IGIY@91061|Bacilli,3F8D4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00484 334390.LAF_1354 0.0 1669.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,3F46M@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 CCPPCCOK_00485 334390.LAF_1355 3.57e-164 460.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,3F5CM@33958|Lactobacillaceae 91061|Bacilli I Acid phosphatase homologues yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 CCPPCCOK_00486 334390.LAF_1356 4.39e-286 783.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,3F3W7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13130 Aldedh CCPPCCOK_00487 334390.LAF_1357 3.78e-180 502.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,3F4E1@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase CCPPCCOK_00488 334390.LAF_1358 3.78e-271 743.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,3F3T0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N CCPPCCOK_00489 575594.ACOH01000003_gene931 3.23e-64 207.0 2DKHQ@1|root,309HG@2|Bacteria,1U53R@1239|Firmicutes,4IEV1@91061|Bacilli,3F4DM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00490 334390.LAF_1360 4.67e-127 361.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag1 - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco CCPPCCOK_00491 334390.LAF_1361 0.0 886.0 COG0477@1|root,COG2814@2|Bacteria,1TS0Y@1239|Firmicutes,4HEMR@91061|Bacilli,3F4GE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 CCPPCCOK_00492 334390.LAF_1362 5.96e-110 315.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,3F67J@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Fur family perR - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR CCPPCCOK_00493 334390.LAF_1363 3.7e-313 855.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease CCPPCCOK_00494 334390.LAF_1364 3.91e-31 108.0 29PMB@1|root,30AJH@2|Bacteria,1U6S6@1239|Firmicutes,4IGJQ@91061|Bacilli,3F8E9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00498 334390.LAF_0347 2.39e-254 696.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,3F4BD@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 CCPPCCOK_00499 334390.LAF_0348 9.22e-217 599.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli,3F4M2@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily hdhL - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N CCPPCCOK_00500 334390.LAF_0349 1.2e-175 491.0 COG0561@1|root,COG0561@2|Bacteria,1V9NB@1239|Firmicutes,4HJAD@91061|Bacilli,3F6H9@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 CCPPCCOK_00501 334390.LAF_0529 3.75e-286 783.0 COG0038@1|root,COG0038@2|Bacteria,1V07H@1239|Firmicutes,4IQYS@91061|Bacilli,3F4QW@33958|Lactobacillaceae 91061|Bacilli P Chloride transporter, ClC family - - - - - - - - - - - - Voltage_CLC CCPPCCOK_00502 334390.LAF_0530 3.39e-121 346.0 COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,3F7ZI@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2507) yslB - - - - - - - - - - - DUF2507 CCPPCCOK_00503 334390.LAF_0531 1.83e-189 526.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,3F446@33958|Lactobacillaceae 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race CCPPCCOK_00504 334390.LAF_0532 8.86e-139 392.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,3F3KD@33958|Lactobacillaceae 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like CCPPCCOK_00505 334390.LAF_0533 3.89e-122 348.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,3F73R@33958|Lactobacillaceae 91061|Bacilli S Phosphoesterase - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 CCPPCCOK_00506 334390.LAF_0534 1.75e-193 537.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3F5E3@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 CCPPCCOK_00507 334390.LAF_0535 4.14e-198 550.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,3F49U@33958|Lactobacillaceae 91061|Bacilli M mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel CCPPCCOK_00508 334390.LAF_0536 5.99e-67 206.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,3F6KB@33958|Lactobacillaceae 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 CCPPCCOK_00509 334390.LAF_0537 4.62e-92 270.0 2DKRN@1|root,30AH6@2|Bacteria,1U6NM@1239|Firmicutes,4IGFK@91061|Bacilli,3F87G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00510 334390.LAF_0538 1.08e-272 745.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,3F3X5@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 CCPPCCOK_00511 334390.LAF_0539 5.94e-238 655.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,3F4AA@33958|Lactobacillaceae 91061|Bacilli K catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 CCPPCCOK_00512 334390.LAF_0540 6.95e-182 508.0 28T2R@1|root,2ZFBY@2|Bacteria,1W6BV@1239|Firmicutes,4HZQK@91061|Bacilli,3F7CC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00513 334390.LAF_0541 1.01e-171 479.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,3F4WF@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg CCPPCCOK_00514 334390.LAF_0542 1.11e-121 361.0 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1VFKC@1239|Firmicutes,4IFHN@91061|Bacilli,3F6HG@33958|Lactobacillaceae 91061|Bacilli M PFAM NLP P60 protein - - - - - - - - - - - - LysM,NLPC_P60 CCPPCCOK_00515 334390.LAF_0543 1.22e-180 520.0 COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,4HCEY@91061|Bacilli,3F5B1@33958|Lactobacillaceae 91061|Bacilli M Dolichyl-phosphate-mannose-protein mannosyltransferase ykcB - - - - - - - - - - - PMT_2 CCPPCCOK_00516 334390.LAF_0543 3.47e-81 259.0 COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,4HCEY@91061|Bacilli,3F5B1@33958|Lactobacillaceae 91061|Bacilli M Dolichyl-phosphate-mannose-protein mannosyltransferase ykcB - - - - - - - - - - - PMT_2 CCPPCCOK_00517 334390.LAF_0544 1.09e-227 627.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,3F4HY@33958|Lactobacillaceae 91061|Bacilli NU Type II IV secretion system protein comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE CCPPCCOK_00518 334390.LAF_0545 4.31e-212 588.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,3F3S9@33958|Lactobacillaceae 91061|Bacilli NU type II secretion system comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF CCPPCCOK_00519 334390.LAF_0546 8.88e-63 192.0 COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli,3F7ZC@33958|Lactobacillaceae 91061|Bacilli U competence protein ComGC comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl CCPPCCOK_00524 334390.LAF_0549 7.51e-204 564.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,3F4CI@33958|Lactobacillaceae 91061|Bacilli L N-6 DNA Methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase CCPPCCOK_00525 334390.LAF_0550 3.9e-286 781.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase CCPPCCOK_00526 334390.LAF_0551 3.19e-146 412.0 COG4186@1|root,COG4186@2|Bacteria,1V40Y@1239|Firmicutes,4HH4J@91061|Bacilli,3F4EX@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos,Metallophos_2 CCPPCCOK_00527 334390.LAF_0552 9.43e-127 360.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,3F66P@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1027) yutD - - - - - - - - - - - DUF1027 CCPPCCOK_00528 334390.LAF_0553 1.01e-182 508.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,3F49D@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like CCPPCCOK_00529 1423807.BACO01000086_gene2495 9.59e-22 95.5 COG4478@1|root,COG4478@2|Bacteria,1V7UW@1239|Firmicutes,4HHH4@91061|Bacilli,3F4YP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1461) - - - - - - - - - - - - DUF1461 CCPPCCOK_00530 334390.LAF_0554 2.38e-141 400.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F4KG@33958|Lactobacillaceae 91061|Bacilli S SNARE-like domain protein dedA - - ko:K03975 - - - - ko00000 - - - SNARE_assoc CCPPCCOK_00531 334390.LAF_0778 2.21e-114 336.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,3F43M@33958|Lactobacillaceae 91061|Bacilli L hmm pf00665 - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve CCPPCCOK_00532 1423814.HMPREF0549_1438 0.0 1492.0 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,3F3UD@33958|Lactobacillaceae 91061|Bacilli S Phage plasmid primase, P4 - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1 CCPPCCOK_00533 1423814.HMPREF0549_1436 4.88e-59 182.0 2E38J@1|root,32Y88@2|Bacteria,1VAXK@1239|Firmicutes,4HNXW@91061|Bacilli,3F791@33958|Lactobacillaceae 91061|Bacilli S VRR_NUC - - - - - - - - - - - - VRR_NUC CCPPCCOK_00534 575594.ACOH01000006_gene280 0.0 876.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,3FCEQ@33958|Lactobacillaceae 91061|Bacilli L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N CCPPCCOK_00535 575594.ACOH01000006_gene279 1.15e-109 315.0 2A2FF@1|root,30QSJ@2|Bacteria,1V1Z3@1239|Firmicutes,4IEZ7@91061|Bacilli,3F52R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00536 557436.Lreu_1774 2.59e-135 391.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve CCPPCCOK_00537 1423814.HMPREF0549_1432 4.66e-128 363.0 28IR9@1|root,2Z8QS@2|Bacteria,1TV6T@1239|Firmicutes,4HCA9@91061|Bacilli,3F5G5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Terminase_4 CCPPCCOK_00538 324831.LGAS_1480 8.89e-288 786.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,4HC9M@91061|Bacilli,3F5AA@33958|Lactobacillaceae 91061|Bacilli KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc CCPPCCOK_00539 324831.LGAS_1481 1.56e-132 377.0 2948F@1|root,2ZRNR@2|Bacteria,1V25Y@1239|Firmicutes,4HEHF@91061|Bacilli,3F5VX@33958|Lactobacillaceae 91061|Bacilli S Psort location Cytoplasmic, score - - - - - - - - - - - - - CCPPCCOK_00540 585524.HMPREF0493_1583 1.19e-41 136.0 2DKJR@1|root,309R8@2|Bacteria,1U5J7@1239|Firmicutes,4IG29@91061|Bacilli,3F7H0@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF5049) - - - - - - - - - - - - DUF5049 CCPPCCOK_00541 525309.HMPREF0494_0888 0.0 1053.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,3F51U@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name - - - - - - - - - - - - Terminase_1 CCPPCCOK_00542 324831.LGAS_1483 3.93e-309 842.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HHWD@91061|Bacilli,3F42D@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal CCPPCCOK_00543 324831.LGAS_1484 3.02e-152 428.0 COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,4HBZH@91061|Bacilli,3F5E9@33958|Lactobacillaceae 91061|Bacilli OU Belongs to the peptidase S14 family - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease CCPPCCOK_00544 324831.LGAS_1485 3.9e-267 733.0 COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,4HCCS@91061|Bacilli,3F4Y2@33958|Lactobacillaceae 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid CCPPCCOK_00545 575594.ACOH01000006_gene269 1.78e-56 176.0 2E3C8@1|root,32YBI@2|Bacteria,1VETG@1239|Firmicutes,4IS2S@91061|Bacilli,3FA1K@33958|Lactobacillaceae 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 CCPPCCOK_00546 324831.LGAS_1486 8.4e-85 250.0 COG5614@1|root,COG5614@2|Bacteria,1VBQZ@1239|Firmicutes,4IFGX@91061|Bacilli,3F6FJ@33958|Lactobacillaceae 91061|Bacilli S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join CCPPCCOK_00547 575594.ACOH01000006_gene267 1.25e-88 260.0 COG4824@1|root,COG4824@2|Bacteria,1V3TR@1239|Firmicutes,4IRAT@91061|Bacilli,3F68Y@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage holin family - - - - - - - - - - - - Phage_holin_4_1 CCPPCCOK_00548 324831.LGAS_1490 0.0 1003.0 COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,4IQ08@91061|Bacilli,3F4SH@33958|Lactobacillaceae 91061|Bacilli L Recombinase zinc beta ribbon domain - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom CCPPCCOK_00549 525309.HMPREF0494_0878 0.0 1010.0 COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,4HD54@91061|Bacilli,3FCES@33958|Lactobacillaceae 91061|Bacilli L Recombinase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom CCPPCCOK_00550 334390.LAF_0741 8.85e-288 785.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,3F4SZ@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase dhaT - 1.1.1.202 ko:K00086 ko00561,ko00640,map00561,map00640 - R02377,R03119 RC00087 ko00000,ko00001,ko01000 - - - Fe-ADH CCPPCCOK_00552 575594.ACOH01000002_gene1154 4.54e-195 554.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,3F3WN@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA polymerase type-Y family polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH CCPPCCOK_00553 334390.LAF_0740 6.32e-227 626.0 COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HBNT@91061|Bacilli,3F5CG@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family - - - ko:K02529,ko:K03604 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CCPPCCOK_00554 334390.LAF_0739 0.0 1168.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459 CCPPCCOK_00555 334390.LAF_0738 1.83e-25 103.0 COG2211@1|root,COG2211@2|Bacteria,1TRP7@1239|Firmicutes,4HCUK@91061|Bacilli,3F3YZ@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 CCPPCCOK_00556 334390.LAF_0738 3.09e-257 709.0 COG2211@1|root,COG2211@2|Bacteria,1TRP7@1239|Firmicutes,4HCUK@91061|Bacilli,3F3YZ@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 CCPPCCOK_00557 334390.LAF_0968 4.32e-71 215.0 COG2050@1|root,COG2050@2|Bacteria,1V7G2@1239|Firmicutes,4HIIA@91061|Bacilli,3F7FT@33958|Lactobacillaceae 91061|Bacilli Q Thioesterase superfamily yuxO - - - - - - - - - - - 4HBT CCPPCCOK_00558 334390.LAF_0969 1.2e-201 557.0 COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli,3F5HN@33958|Lactobacillaceae 91061|Bacilli H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) menB GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CCPPCCOK_00559 334390.LAF_0970 0.0 954.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,3F453@33958|Lactobacillaceae 91061|Bacilli H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C CCPPCCOK_00560 334390.LAF_0971 2.14e-278 762.0 COG2271@1|root,COG2271@2|Bacteria,1TP6X@1239|Firmicutes,4IQRU@91061|Bacilli,3F54E@33958|Lactobacillaceae 91061|Bacilli G Transporter, major facilitator family protein - - - - - - - - - - - - MFS_1 CCPPCCOK_00561 334390.LAF_0972 1.46e-262 718.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F5ST@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase adh - 1.1.1.1 ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703 RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CCPPCCOK_00562 334390.LAF_0973 4.58e-269 737.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,3F3Y2@33958|Lactobacillaceae 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP CCPPCCOK_00563 334390.LAF_0974 9.99e-216 595.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3F4VD@33958|Lactobacillaceae 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02385 PALP CCPPCCOK_00564 334390.LAF_0975 1.65e-53 168.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli,3F811@33958|Lactobacillaceae 91061|Bacilli T Belongs to the UPF0237 family XK27_08630 - - ko:K07166 - - - - ko00000 - - - ACT_6 CCPPCCOK_00565 334390.LAF_0976 1.14e-312 853.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli,3F4H2@33958|Lactobacillaceae 91061|Bacilli S UPF0210 protein XK27_08635 - - ko:K09157 - - - - ko00000 - - - DUF711 CCPPCCOK_00566 334390.LAF_0977 1.27e-228 629.0 COG2378@1|root,COG2378@2|Bacteria,1U8E4@1239|Firmicutes,4IQQI@91061|Bacilli,3FBID@33958|Lactobacillaceae 91061|Bacilli K WYL domain - - - - - - - - - - - - HTH_11,WYL CCPPCCOK_00567 334390.LAF_0978 3.96e-89 261.0 COG3576@1|root,COG3576@2|Bacteria,1VGE7@1239|Firmicutes,4HNE7@91061|Bacilli,3F6YB@33958|Lactobacillaceae 91061|Bacilli S pyridoxamine 5-phosphate - - - - - - - - - - - - Putative_PNPOx CCPPCCOK_00568 641146.HMPREF9020_01150 1.29e-45 150.0 2C6A9@1|root,346JA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CCPPCCOK_00570 553178.CAPGI0001_2376 5.56e-07 56.6 COG1216@1|root,COG1216@2|Bacteria,4NRJC@976|Bacteroidetes,1IM6Z@117743|Flavobacteriia,1ESIK@1016|Capnocytophaga 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 CCPPCCOK_00571 334390.LAF_1169 2.37e-152 429.0 COG0765@1|root,COG0765@2|Bacteria,1TQ43@1239|Firmicutes,4HCZV@91061|Bacilli,3FC58@33958|Lactobacillaceae 91061|Bacilli E ABC transporter permease yckA GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 CCPPCCOK_00572 334390.LAF_1168 1.19e-199 553.0 COG0834@1|root,COG0834@2|Bacteria,1UHHG@1239|Firmicutes,4H9NX@91061|Bacilli,3FC57@33958|Lactobacillaceae 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family yckB - - ko:K02030,ko:K02424 ko02010,map02010 M00234,M00236 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 CCPPCCOK_00573 334390.LAF_1167 3.33e-140 396.0 COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli,3F576@33958|Lactobacillaceae 91061|Bacilli S Nitroreductase family XK27_02070 - - ko:K07078 - - - - ko00000 - - - Nitroreductase CCPPCCOK_00574 334390.LAF_1166 3.77e-93 271.0 COG0328@1|root,COG0328@2|Bacteria,1VH2B@1239|Firmicutes,4HIY9@91061|Bacilli,3F7JC@33958|Lactobacillaceae 91061|Bacilli L Ribonuclease HI rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H,RVT_3 CCPPCCOK_00575 334390.LAF_1165 8.6e-93 271.0 2BZWG@1|root,2ZPAS@2|Bacteria,1W31C@1239|Firmicutes,4I09H@91061|Bacilli,3F6SQ@33958|Lactobacillaceae 91061|Bacilli S Family of unknown function (DUF5322) esbA - - - - - - - - - - - DUF5322 CCPPCCOK_00576 334390.LAF_1164 1.27e-99 289.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,3F66R@33958|Lactobacillaceae 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 CCPPCCOK_00577 334390.LAF_1163 2.57e-223 615.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,3F3P6@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CCPPCCOK_00578 334390.LAF_1162 8.46e-264 722.0 COG0505@1|root,COG0505@2|Bacteria,1VTN5@1239|Firmicutes,4HT8S@91061|Bacilli,3FC4C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase CCPPCCOK_00579 334390.LAF_1161 0.0 1632.0 COG0458@1|root,COG0458@2|Bacteria,1VRNP@1239|Firmicutes,4HTJU@91061|Bacilli,3FC3W@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3 CCPPCCOK_00580 334390.LAF_1160 4.36e-155 434.0 COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli,3F60I@33958|Lactobacillaceae 91061|Bacilli P Eukaryotic-type carbonic anhydrase - - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase CCPPCCOK_00581 334390.LAF_0146 1.55e-120 345.0 COG4300@1|root,COG4300@2|Bacteria,1VUU3@1239|Firmicutes,4HVGH@91061|Bacilli,3F6NP@33958|Lactobacillaceae 91061|Bacilli P Cadmium resistance transporter - - - - - - - - - - - - Cad CCPPCCOK_00582 334390.LAF_0147 5.03e-43 140.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination ydzE - - - - - - - - - - - EamA CCPPCCOK_00583 334390.LAF_0148 5.13e-34 118.0 COG0599@1|root,COG0599@2|Bacteria,1VFY0@1239|Firmicutes,4IBY8@91061|Bacilli,3F88I@33958|Lactobacillaceae 91061|Bacilli O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD CCPPCCOK_00584 334390.LAF_0149 1.54e-113 352.0 29QSW@1|root,30BSR@2|Bacteria,1U8KN@1239|Firmicutes,4IIIM@91061|Bacilli,3FB34@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00585 334390.LAF_0150 0.0 967.0 COG5386@1|root,COG5386@2|Bacteria,1VES7@1239|Firmicutes,4HIEC@91061|Bacilli,3F71K@33958|Lactobacillaceae 91061|Bacilli M Iron Transport-associated domain - - - - - - - - - - - - Gram_pos_anchor,NEAT CCPPCCOK_00586 334390.LAF_0151 1.31e-129 374.0 COG5386@1|root,COG5386@2|Bacteria,1VES7@1239|Firmicutes,4HIEC@91061|Bacilli,3F6SK@33958|Lactobacillaceae 91061|Bacilli M Iron Transport-associated domain - - - ko:K14193 ko05150,map05150 - - - ko00000,ko00001 - - - NEAT CCPPCCOK_00587 334390.LAF_0152 7.99e-196 544.0 COG0614@1|root,COG0614@2|Bacteria,1UIJ9@1239|Firmicutes,4HDDF@91061|Bacilli,3F4ZN@33958|Lactobacillaceae 91061|Bacilli P Periplasmic binding protein isdE - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 CCPPCCOK_00588 334390.LAF_0153 2.57e-200 557.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4H9QQ@91061|Bacilli,3F4T9@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily isdF - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD CCPPCCOK_00589 334390.LAF_0154 2.21e-181 504.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HCKS@91061|Bacilli,3F4NB@33958|Lactobacillaceae 91061|Bacilli HP ABC transporter, ATP-binding protein - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran CCPPCCOK_00590 334390.LAF_0155 2.25e-301 823.0 COG0477@1|root,COG0477@2|Bacteria,1TQIJ@1239|Firmicutes,4HAM0@91061|Bacilli,3F3N4@33958|Lactobacillaceae 91061|Bacilli EGP Sugar (and other) transporter proP - - ko:K03761,ko:K03762 - - - - ko00000,ko02000 2.A.1.6.2,2.A.1.6.4 - - MFS_1,Sugar_tr CCPPCCOK_00591 334390.LAF_0157 1.15e-92 278.0 2DIUI@1|root,3045J@2|Bacteria,1U78P@1239|Firmicutes,4IH3J@91061|Bacilli,3F94E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor CCPPCCOK_00592 334390.LAF_0158 6.97e-204 563.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,3F4GK@33958|Lactobacillaceae 91061|Bacilli L exodeoxyribonuclease III xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos CCPPCCOK_00593 334390.LAF_1685 9.26e-216 595.0 COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli,3F3K8@33958|Lactobacillaceae 91061|Bacilli GK ROK family scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK CCPPCCOK_00594 334390.LAF_1684 7.48e-298 815.0 COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,4HEHY@91061|Bacilli,3F3KX@33958|Lactobacillaceae 91061|Bacilli V MATE efflux family protein mepA - - ko:K18908 - M00705 - - ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 - - MatE CCPPCCOK_00595 334390.LAF_1683 3.09e-286 782.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,3F3X1@33958|Lactobacillaceae 91061|Bacilli P ammonium transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp CCPPCCOK_00597 334390.LAF_1682 2.77e-172 481.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F3NW@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran CCPPCCOK_00598 334390.LAF_1681 3.76e-193 538.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 CCPPCCOK_00599 334390.LAF_1680 3.41e-232 639.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter ABC-SBP - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind CCPPCCOK_00600 334390.LAF_1679 0.0 1004.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn CCPPCCOK_00601 334390.LAF_1678 1.35e-261 717.0 COG2404@1|root,COG2404@2|Bacteria,1TQPZ@1239|Firmicutes,4HCSM@91061|Bacilli,3F5R4@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain yngD - - ko:K07097 - - - - ko00000 - - - DHHA1 CCPPCCOK_00603 334390.LAF_1676 8.3e-141 399.0 COG1376@1|root,COG1376@2|Bacteria,1V4KP@1239|Firmicutes,4HIBF@91061|Bacilli,3F6PH@33958|Lactobacillaceae 91061|Bacilli M ErfK YbiS YcfS YnhG yciB - - - - - - - - - - - YkuD CCPPCCOK_00604 334390.LAF_1675 1.64e-108 312.0 COG1780@1|root,COG1780@2|Bacteria,1V764@1239|Firmicutes,4HJVP@91061|Bacilli,3F4MF@33958|Lactobacillaceae 91061|Bacilli F NrdI Flavodoxin like nrdI GO:0000166,GO:0003674,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0019538,GO:0032553,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI CCPPCCOK_00605 334390.LAF_1674 0.0 1437.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,3F3XG@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN CCPPCCOK_00606 334390.LAF_1673 3.77e-217 599.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,3F5T7@33958|Lactobacillaceae 91061|Bacilli F Ribonucleotide reductase, small chain nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm CCPPCCOK_00607 334390.LAF_1672 8.41e-235 645.0 COG0208@1|root,COG0208@2|Bacteria,1V0Y9@1239|Firmicutes,4HC0F@91061|Bacilli,3F63P@33958|Lactobacillaceae 91061|Bacilli F Ribonucleotide reductase, small chain - - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm CCPPCCOK_00608 334390.LAF_1671 0.0 1039.0 2EM25@1|root,33ERN@2|Bacteria,1VK4A@1239|Firmicutes,4HRGD@91061|Bacilli,3F53P@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2325) - - - - - - - - - - - - DUF2325 CCPPCCOK_00609 334390.LAF_1670 5.93e-149 419.0 COG0546@1|root,COG0546@2|Bacteria,1V7U6@1239|Firmicutes,4HJ9I@91061|Bacilli,3F658@33958|Lactobacillaceae 91061|Bacilli S HAD hydrolase, family IA, variant - - - - - - - - - - - - HAD_2 CCPPCCOK_00610 334390.LAF_1669 2.73e-227 625.0 COG0596@1|root,COG0596@2|Bacteria,1UJIF@1239|Firmicutes,4ITAC@91061|Bacilli,3FBV8@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 CCPPCCOK_00611 334390.LAF_1218 8.62e-63 203.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 CCPPCCOK_00612 1400520.LFAB_13535 0.0 874.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp CCPPCCOK_00613 334390.LAF_1829 1.56e-62 203.0 29PIM@1|root,30AGS@2|Bacteria,1U6N1@1239|Firmicutes,4IGEW@91061|Bacilli,3F86A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00614 334390.LAF_1830 0.0 1194.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,3F3TC@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD CCPPCCOK_00615 334390.LAF_1831 4.87e-96 285.0 COG1525@1|root,COG1525@2|Bacteria,1V8AM@1239|Firmicutes,4IPMQ@91061|Bacilli,3F813@33958|Lactobacillaceae 91061|Bacilli L nuclease - - - - - - - - - - - - Ada_Zn_binding CCPPCCOK_00616 334390.LAF_1832 8.47e-207 572.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HHHQ@91061|Bacilli,3F4MB@33958|Lactobacillaceae 91061|Bacilli F DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 CCPPCCOK_00617 334390.LAF_1833 1.89e-144 407.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HMGQ@91061|Bacilli,3F56W@33958|Lactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 CCPPCCOK_00618 334390.LAF_1834 0.0 997.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,3F3UE@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M CCPPCCOK_00619 334390.LAF_1835 0.0 1008.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,3F3UE@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CCPPCCOK_00620 334390.LAF_1836 0.0 1308.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,3F3NT@33958|Lactobacillaceae 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 CCPPCCOK_00621 1203076.CAKF01000016_gene1780 1.25e-283 783.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid lysP - - ko:K03293,ko:K11733 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.2 - - AA_permease CCPPCCOK_00622 334390.LAF_0350 0.0 1081.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,3F457@33958|Lactobacillaceae 91061|Bacilli G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CCPPCCOK_00623 334390.LAF_0351 1.02e-144 408.0 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,4HA8H@91061|Bacilli,3F4RZ@33958|Lactobacillaceae 91061|Bacilli S HD containing hydrolase-like enzyme yfbR - - ko:K07023 - - - - ko00000 - - - HD_2 CCPPCCOK_00625 334390.LAF_0353 0.0 1291.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,3F3XM@33958|Lactobacillaceae 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB CCPPCCOK_00626 334390.LAF_0354 0.0 1890.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,3F4TZ@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran CCPPCCOK_00627 334390.LAF_0355 5.07e-261 715.0 2BK8E@1|root,32ENE@2|Bacteria,1U7VC@1239|Firmicutes,4IHSS@91061|Bacilli,3FA80@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00628 334390.LAF_0356 1.35e-206 571.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,3F4NY@33958|Lactobacillaceae 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 CCPPCCOK_00629 334390.LAF_0357 2e-240 660.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,3F4D5@33958|Lactobacillaceae 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 CCPPCCOK_00630 334390.LAF_0358 1.92e-213 590.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,3F4AB@33958|Lactobacillaceae 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N CCPPCCOK_00631 334390.LAF_0359 2.52e-156 438.0 COG0819@1|root,COG0819@2|Bacteria,1V9SR@1239|Firmicutes,4HK9S@91061|Bacilli,3F606@33958|Lactobacillaceae 91061|Bacilli K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway - - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 CCPPCCOK_00632 334390.LAF_0360 2.96e-132 375.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,3F3M0@33958|Lactobacillaceae 91061|Bacilli O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease CCPPCCOK_00636 334390.LAF_1709 0.0 1220.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaK - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger CCPPCCOK_00637 1423814.HMPREF0549_1208 1.78e-22 92.0 2DZIG@1|root,32VBI@2|Bacteria,1VIUB@1239|Firmicutes,4HRZP@91061|Bacilli,3F7EN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4870 CCPPCCOK_00638 334390.LAF_1707 1.06e-149 421.0 COG0619@1|root,COG0619@2|Bacteria,1V679@1239|Firmicutes,4HFRQ@91061|Bacilli,3FBEQ@33958|Lactobacillaceae 91061|Bacilli P Cobalt transport protein - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ CCPPCCOK_00639 334390.LAF_1706 0.0 883.0 COG0488@1|root,COG0488@2|Bacteria,1UI2R@1239|Firmicutes,4ISG8@91061|Bacilli,3F3WM@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran CCPPCCOK_00640 334390.LAF_1705 4.09e-131 372.0 COG4721@1|root,COG4721@2|Bacteria,1V39N@1239|Firmicutes,4HF32@91061|Bacilli,3F4QM@33958|Lactobacillaceae 91061|Bacilli S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt CCPPCCOK_00641 334390.LAF_1704 9.38e-229 630.0 COG1957@1|root,COG1957@2|Bacteria,1TSAR@1239|Firmicutes,4HDCS@91061|Bacilli,3F4A3@33958|Lactobacillaceae 91061|Bacilli F nucleoside hydrolase iunH1 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro CCPPCCOK_00642 334390.LAF_1703 1.51e-235 648.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,3F3NQ@33958|Lactobacillaceae 91061|Bacilli C Ferredoxin--NADP reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 CCPPCCOK_00643 334390.LAF_1702 0.0 1117.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4T3@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase CCPPCCOK_00644 334390.LAF_1701 9.17e-45 145.0 COG2608@1|root,COG2608@2|Bacteria,1VFJ8@1239|Firmicutes,4HNY2@91061|Bacilli,3F830@33958|Lactobacillaceae 91061|Bacilli P Heavy-metal-associated domain copZ - - - - - - - - - - - HMA CCPPCCOK_00645 334390.LAF_1700 4.64e-129 366.0 COG0783@1|root,COG0783@2|Bacteria,1VB1X@1239|Firmicutes,4HMJG@91061|Bacilli,3F4SN@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Dps family dpsB - - - - - - - - - - - Ferritin CCPPCCOK_00646 334390.LAF_1699 3.81e-142 402.0 COG0664@1|root,COG0664@2|Bacteria,1UZT0@1239|Firmicutes,4HFR2@91061|Bacilli,3FBKF@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, cAMP Regulatory protein flp - - ko:K21562 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding CCPPCCOK_00647 334390.LAF_1698 1.3e-110 320.0 29P3K@1|root,30A1T@2|Bacteria,1U62W@1239|Firmicutes,4IFS1@91061|Bacilli,3F6X0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00648 334390.LAF_1697 0.0 1375.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase CCPPCCOK_00649 334390.LAF_1696 3.31e-162 453.0 COG0406@1|root,COG0406@2|Bacteria,1TQWQ@1239|Firmicutes,4HFDZ@91061|Bacilli,3FC5M@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase family pgm3 - - - - - - - - - - - His_Phos_1 CCPPCCOK_00650 334390.LAF_1695 5.62e-192 534.0 COG0702@1|root,COG0702@2|Bacteria,1TT90@1239|Firmicutes,4HC1K@91061|Bacilli,3F4UU@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family qorB - 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - NAD_binding_10,NmrA CCPPCCOK_00651 334390.LAF_1694 1.58e-301 824.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,3F3Y7@33958|Lactobacillaceae 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16169 - - - - ko00000,ko02000 2.A.40,2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease CCPPCCOK_00652 334390.LAF_1693 6.8e-220 606.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F4B8@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA CCPPCCOK_00653 334390.LAF_1692 1.42e-215 594.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,3F50K@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 CCPPCCOK_00654 334390.LAF_1691 1.01e-182 509.0 COG0861@1|root,COG0861@2|Bacteria,1UVIJ@1239|Firmicutes,4HEKW@91061|Bacilli,3F3WS@33958|Lactobacillaceae 91061|Bacilli P membrane yceF - - ko:K05794 - - - - ko00000 - - - TerC CCPPCCOK_00655 334390.LAF_1690 8.45e-75 223.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F7I4@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin CCPPCCOK_00656 334390.LAF_1689 1.72e-213 590.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,3F3S5@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB,Rib_5-P_isom_A CCPPCCOK_00657 334390.LAF_1688 3.45e-207 573.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,3F3XC@33958|Lactobacillaceae 91061|Bacilli I Dehydrogenase glxR - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 CCPPCCOK_00658 334390.LAF_1687 2.41e-235 647.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,3F4JE@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family fruR3 - - ko:K02529,ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CCPPCCOK_00661 334390.LAF_0496 1.04e-114 328.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,3F5VY@33958|Lactobacillaceae 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin CCPPCCOK_00662 334390.LAF_0497 0.0 1799.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,3F3RB@33958|Lactobacillaceae 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 CCPPCCOK_00663 334390.LAF_0498 0.0 865.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,3F498@33958|Lactobacillaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M CCPPCCOK_00664 334390.LAF_0499 5.3e-150 421.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,3F5IM@33958|Lactobacillaceae 91061|Bacilli L DNA repair protein radC - - ko:K03630 - - - - ko00000 - - - RadC CCPPCCOK_00665 334390.LAF_0500 1.34e-232 641.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F3ZV@33958|Lactobacillaceae 91061|Bacilli D cell shape determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl CCPPCCOK_00666 334390.LAF_0501 1.37e-187 523.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,3F3MC@33958|Lactobacillaceae 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC CCPPCCOK_00667 334390.LAF_0502 9.04e-120 342.0 COG2891@1|root,COG2891@2|Bacteria,1VEV7@1239|Firmicutes,4HPAC@91061|Bacilli,3F6PG@33958|Lactobacillaceae 91061|Bacilli M rod shape-determining protein MreD mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD CCPPCCOK_00668 334390.LAF_0503 3.81e-142 402.0 COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli,3F3VF@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 CCPPCCOK_00669 334390.LAF_0504 4.86e-149 419.0 COG1126@1|root,COG1126@2|Bacteria,1UYAZ@1239|Firmicutes,4HFTM@91061|Bacilli,3FC39@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran CCPPCCOK_00670 334390.LAF_0505 1.65e-205 568.0 COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,4HF14@91061|Bacilli,3F3WC@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein aatB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CCPPCCOK_00671 334390.LAF_0506 1.1e-296 810.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,3F3SA@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 inactive domain protein ymfF - - - - - - - - - - - Peptidase_M16_C CCPPCCOK_00672 334390.LAF_0507 0.0 863.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,3F4MU@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C CCPPCCOK_00673 334390.LAF_0508 1.64e-151 436.0 COG1426@1|root,COG1426@2|Bacteria,1V9EA@1239|Firmicutes,4HPRN@91061|Bacilli,3FC82@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain - - - - - - - - - - - - DUF4115,HTH_25 CCPPCCOK_00674 334390.LAF_0509 1.79e-132 376.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,3F4BI@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf CCPPCCOK_00675 334390.LAF_0510 1.62e-293 801.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,3F4I4@33958|Lactobacillaceae 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth CCPPCCOK_00676 334390.LAF_0511 2.26e-244 672.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA CCPPCCOK_00677 334390.LAF_0512 2.27e-305 840.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,3F3WX@33958|Lactobacillaceae 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 CCPPCCOK_00678 334390.LAF_0513 0.0 1674.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,3F4A5@33958|Lactobacillaceae 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V CCPPCCOK_00679 334390.LAF_0514 0.0 1256.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,3F3PK@33958|Lactobacillaceae 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C CCPPCCOK_00680 334390.LAF_0515 1.77e-135 384.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,3F42W@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N CCPPCCOK_00681 334390.LAF_0516 1.71e-241 664.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,3F47S@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N CCPPCCOK_00682 334390.LAF_0517 5.14e-225 620.0 COG0343@1|root,COG0343@2|Bacteria 2|Bacteria F queuine tRNA-ribosyltransferase activity - - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT CCPPCCOK_00683 334390.LAF_0518 1.11e-68 210.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,3F7EY@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC CCPPCCOK_00684 334390.LAF_0519 3.41e-231 636.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CCPPCCOK_00685 334390.LAF_0520 1.7e-300 823.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,3F4FQ@33958|Lactobacillaceae 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C CCPPCCOK_00686 334390.LAF_0521 0.0 1747.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,3F3QS@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD CCPPCCOK_00687 334390.LAF_0522 1.06e-57 178.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,3F7EG@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 CCPPCCOK_00688 334390.LAF_0523 4.97e-97 282.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,3F6NI@33958|Lactobacillaceae 91061|Bacilli J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX CCPPCCOK_00689 334390.LAF_0524 3.99e-55 173.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,3F6X3@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 CCPPCCOK_00690 334390.LAF_0525 3.2e-211 584.0 COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli,3F3TJ@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII CCPPCCOK_00691 334390.LAF_0526 2.23e-119 341.0 COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,3F643@33958|Lactobacillaceae 91061|Bacilli S Colicin V production protein cvpA - - - - - - - - - - - Colicin_V CCPPCCOK_00692 334390.LAF_0527 0.0 1502.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,3F4DX@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr CCPPCCOK_00693 334390.LAF_0528 1.66e-71 214.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F6Y3@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin CCPPCCOK_00694 334390.LAF_0789 1.28e-131 374.0 COG4300@1|root,COG4300@2|Bacteria,1TPQX@1239|Firmicutes,4HAME@91061|Bacilli,3FB3W@33958|Lactobacillaceae 91061|Bacilli P Cadmium resistance transporter cadD - - - - - - - - - - - Cad CCPPCCOK_00695 334390.LAF_0790 1.55e-151 427.0 COG1811@1|root,COG1811@2|Bacteria,1U5PM@1239|Firmicutes,4HEHT@91061|Bacilli,3F56J@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 CCPPCCOK_00696 334390.LAF_0791 1.45e-135 382.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,3F3YI@33958|Lactobacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR CCPPCCOK_00697 334390.LAF_0793 3.44e-201 557.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 CCPPCCOK_00698 334390.LAF_0794 4.53e-127 360.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,3F3YI@33958|Lactobacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR CCPPCCOK_00699 334390.LAF_0798 6.32e-51 162.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi CCPPCCOK_00700 334390.LAF_0799 4.18e-89 262.0 COG3223@1|root,COG3223@2|Bacteria,1VCG5@1239|Firmicutes,4HKQN@91061|Bacilli,3FBQN@33958|Lactobacillaceae 91061|Bacilli S Phosphate-starvation-inducible E psiE - - ko:K13256 - - - - ko00000 - - - PsiE CCPPCCOK_00701 334390.LAF_0800 6.81e-192 533.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin CCPPCCOK_00702 334390.LAF_0801 6.14e-147 414.0 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,3F5ZQ@33958|Lactobacillaceae 91061|Bacilli H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI CCPPCCOK_00703 334390.LAF_0802 4.46e-184 512.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin CCPPCCOK_00704 525309.HMPREF0494_0059 6.08e-180 501.0 COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,3F43J@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK CCPPCCOK_00705 334390.LAF_0804 0.0 1255.0 COG1807@1|root,COG1807@2|Bacteria,1UYWB@1239|Firmicutes,4HTZD@91061|Bacilli,3F5AG@33958|Lactobacillaceae 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - CCPPCCOK_00706 1423780.LOT_2161 0.0 1176.0 COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4HE0R@91061|Bacilli,3F554@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer cas9 - - ko:K09952 - - - - ko00000,ko01000,ko02048 - - - Cas9-BH,Cas9_PI,Cas9_REC,HNH_4 CCPPCCOK_00707 511437.Lbuc_1876 8.7e-116 342.0 COG1518@1|root,COG1518@2|Bacteria,1TT0J@1239|Firmicutes,4HC5E@91061|Bacilli,3F3RW@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1 CCPPCCOK_00708 1545701.LACWKB10_0720 3.41e-46 150.0 COG3512@1|root,COG3512@2|Bacteria,1VEH4@1239|Firmicutes,4HNYR@91061|Bacilli,3F7KD@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 CCPPCCOK_00709 575605.ACQN01000040_gene926 6.7e-43 151.0 28XJS@1|root,2ZJGW@2|Bacteria,1W4NV@1239|Firmicutes,4I15N@91061|Bacilli,3F6XN@33958|Lactobacillaceae 91061|Bacilli S CRISPR-associated protein (Cas_Csn2) - - - - - - - - - - - - Cas_Csn2 CCPPCCOK_00711 1056816.JAFQ01000004_gene4941 1.73e-26 106.0 COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria,4FY44@85025|Nocardiaceae 201174|Actinobacteria I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3 CCPPCCOK_00712 1122918.KB907271_gene1687 1.08e-41 144.0 COG0657@1|root,COG0657@2|Bacteria,1TRYT@1239|Firmicutes,4HC3I@91061|Bacilli,2759I@186822|Paenibacillaceae 91061|Bacilli I Esterase lipase - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3 CCPPCCOK_00714 334390.LAF_0805 3.48e-124 356.0 COG5542@1|root,COG5542@2|Bacteria,1W76F@1239|Firmicutes,4II3P@91061|Bacilli,3FAKF@33958|Lactobacillaceae 91061|Bacilli S integral membrane protein - - - - - - - - - - - - - CCPPCCOK_00715 334390.LAF_0806 3.36e-221 610.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N CCPPCCOK_00717 334390.LAF_0807 4.82e-72 216.0 2FCQV@1|root,344U2@2|Bacteria,1W026@1239|Firmicutes,4HZ7F@91061|Bacilli,3F7FM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00718 334390.LAF_0808 9.06e-232 637.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,3F47Z@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA CCPPCCOK_00719 334390.LAF_0809 1.5e-174 487.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,3F64Z@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA CCPPCCOK_00720 334390.LAF_0810 4.23e-76 227.0 2C2I6@1|root,30AJ5@2|Bacteria,1U6RR@1239|Firmicutes,4IGJ7@91061|Bacilli,3F8DM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00721 334390.LAF_0811 0.0 1469.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS CCPPCCOK_00722 334390.LAF_0812 3.12e-100 290.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,3F6GK@33958|Lactobacillaceae 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase CCPPCCOK_00723 334390.LAF_0813 5.22e-111 319.0 COG1846@1|root,COG1846@2|Bacteria,1W4X8@1239|Firmicutes,4I172@91061|Bacilli,3F8CB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - MarR CCPPCCOK_00724 334390.LAF_0814 2.41e-280 767.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,3F3Y2@33958|Lactobacillaceae 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP CCPPCCOK_00725 334390.LAF_0815 4.6e-271 741.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,3F4CK@33958|Lactobacillaceae 91061|Bacilli E Cys/Met metabolism PLP-dependent enzyme metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP CCPPCCOK_00727 1423806.JCM15457_2513 6.31e-78 243.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HDQ8@91061|Bacilli,3F77M@33958|Lactobacillaceae 91061|Bacilli ET Bacterial periplasmic substrate-binding proteins yxeM - - ko:K16961 ko02010,map02010 M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CCPPCCOK_00728 203120.LEUM_0109 2.07e-59 190.0 COG0454@1|root,COG0456@2|Bacteria,1V9FA@1239|Firmicutes,4HJ4W@91061|Bacilli 91061|Bacilli K acetyltransferase yxeL - - - - - - - - - - - Acetyltransf_1 CCPPCCOK_00729 1423806.JCM15457_2516 4.87e-98 293.0 COG0765@1|root,COG0765@2|Bacteria,1UZ2C@1239|Firmicutes,4HF77@91061|Bacilli,3F7IY@33958|Lactobacillaceae 91061|Bacilli U ABC transporter, permease protein yxeN - - ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 M00236,M00585,M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.13 - - BPD_transp_1 CCPPCCOK_00730 1423806.JCM15457_2517 2.15e-100 298.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F97V@33958|Lactobacillaceae 91061|Bacilli E ATPases associated with a variety of cellular activities yxeO - - ko:K16963 ko02010,map02010 M00586 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran CCPPCCOK_00731 525309.HMPREF0494_0406 8.13e-185 524.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,3FC42@33958|Lactobacillaceae 91061|Bacilli E Peptidase family M20/M25/M40 hipO2 - - ko:K01436,ko:K21613 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CCPPCCOK_00732 797515.HMPREF9103_00528 3.62e-215 607.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HDVU@91061|Bacilli,3F5ZH@33958|Lactobacillaceae 91061|Bacilli F Adenylosuccinate lyase C-terminus - - 4.3.2.2,5.5.1.2 ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 M00048,M00049 R01083,R03307,R04559 RC00379,RC00444,RC00445,RC00902 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 CCPPCCOK_00733 797515.HMPREF9103_00534 5.9e-108 333.0 COG2079@1|root,COG2079@2|Bacteria,1TSD7@1239|Firmicutes,4IF57@91061|Bacilli,3F5NR@33958|Lactobacillaceae 91061|Bacilli S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD CCPPCCOK_00735 334390.LAF_0820 9.72e-147 414.0 COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,4HGE1@91061|Bacilli,3F3XD@33958|Lactobacillaceae 91061|Bacilli P ABC transporter, permease protein glnP9 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 CCPPCCOK_00736 334390.LAF_0821 1.32e-146 414.0 COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,4HGVA@91061|Bacilli,3F45E@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnP7 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 CCPPCCOK_00737 334390.LAF_0822 1.19e-174 487.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4HDK7@91061|Bacilli,3FC3P@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran CCPPCCOK_00738 334390.LAF_0823 5.25e-197 546.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HFBQ@91061|Bacilli,3F54P@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein cjaA - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CCPPCCOK_00739 334390.LAF_0824 5.44e-176 490.0 COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,4HHQ8@91061|Bacilli,3FC9P@33958|Lactobacillaceae 91061|Bacilli IQ KR domain - - - - - - - - - - - - adh_short_C2 CCPPCCOK_00740 334390.LAF_0825 5.8e-271 742.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,3F3KS@33958|Lactobacillaceae 91061|Bacilli E Homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 CCPPCCOK_00741 334390.LAF_0826 1.36e-203 562.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,3F5CA@33958|Lactobacillaceae 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to metAA - 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS CCPPCCOK_00742 334390.LAF_0827 0.0 900.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid ybgF - - ko:K02205,ko:K03293,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - - AA_permease CCPPCCOK_00743 334390.LAF_0828 1.95e-221 610.0 COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli,3F4UT@33958|Lactobacillaceae 91061|Bacilli H homocysteine S-methyltransferase mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans CCPPCCOK_00744 334390.LAF_0829 3.92e-217 597.0 COG3001@1|root,COG3001@2|Bacteria,1U79A@1239|Firmicutes,4HAZS@91061|Bacilli,3F3RK@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase enzyme family - - - - - - - - - - - - Fructosamin_kin CCPPCCOK_00745 334390.LAF_0830 1.55e-226 625.0 COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,4HAV3@91061|Bacilli,3FC12@33958|Lactobacillaceae 91061|Bacilli M Ami_3 cwlD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 CCPPCCOK_00746 334390.LAF_0831 1.27e-249 684.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HVEG@91061|Bacilli,3F4PZ@33958|Lactobacillaceae 91061|Bacilli H Lipoate-protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C CCPPCCOK_00747 334390.LAF_0832 1.39e-314 856.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,3F3M3@33958|Lactobacillaceae 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His CCPPCCOK_00748 334390.LAF_0833 0.0 1184.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,3F4PE@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon CCPPCCOK_00749 334390.LAF_0834 1.1e-165 462.0 COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,4HHTX@91061|Bacilli,3F4AV@33958|Lactobacillaceae 91061|Bacilli F glutamine amidotransferase - - - - - - - - - - - - GATase CCPPCCOK_00750 334390.LAF_0835 3.81e-31 109.0 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,3F81Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 CCPPCCOK_00751 334390.LAF_0836 2.52e-92 271.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,3F6I0@33958|Lactobacillaceae 91061|Bacilli S YqeY-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY CCPPCCOK_00752 334390.LAF_0837 1.75e-228 630.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,3F4E7@33958|Lactobacillaceae 91061|Bacilli T phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH CCPPCCOK_00753 334390.LAF_0838 8.34e-104 300.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,3F516@33958|Lactobacillaceae 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 CCPPCCOK_00754 334390.LAF_0839 7.64e-88 258.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,3F7DC@33958|Lactobacillaceae 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar CCPPCCOK_00755 334390.LAF_0840 8.91e-218 600.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,3F3WQ@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 CCPPCCOK_00756 334390.LAF_0841 3.58e-198 548.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,3F56P@33958|Lactobacillaceae 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N CCPPCCOK_00757 334390.LAF_0842 3.59e-240 659.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,3F3T8@33958|Lactobacillaceae 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e CCPPCCOK_00758 334390.LAF_0843 0.0 1352.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,3F4G8@33958|Lactobacillaceae 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f CCPPCCOK_00759 334390.LAF_0844 0.0 1231.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,3F3N1@33958|Lactobacillaceae 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 CCPPCCOK_00760 334390.LAF_0845 1.21e-264 726.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,3F4CF@33958|Lactobacillaceae 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 CCPPCCOK_00761 334390.LAF_0917 4.3e-312 852.0 COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli,3F4XT@33958|Lactobacillaceae 91061|Bacilli P Major Facilitator Superfamily yhjX - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 CCPPCCOK_00762 334390.LAF_0916 2.2e-151 426.0 COG1811@1|root,COG1811@2|Bacteria,1U5PM@1239|Firmicutes,4HEHT@91061|Bacilli,3F56J@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 CCPPCCOK_00763 334390.LAF_0915 0.0 885.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3NB@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N CCPPCCOK_00765 334390.LAF_0913 0.0 1143.0 COG0444@1|root,COG0444@2|Bacteria,1TS8Q@1239|Firmicutes,4HCZ1@91061|Bacilli,3F4T6@33958|Lactobacillaceae 91061|Bacilli EP Psort location Cytoplasmic, score - - - - - - - - - - - - PEPCK_ATP CCPPCCOK_00766 334390.LAF_0912 2.17e-306 834.0 COG0402@1|root,COG0402@2|Bacteria,1TRK2@1239|Firmicutes,4HAAV@91061|Bacilli,3F4JP@33958|Lactobacillaceae 91061|Bacilli F cytosine deaminase codA - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - Amidohydro_3 CCPPCCOK_00767 334390.LAF_0911 2.4e-312 852.0 COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,4HA3B@91061|Bacilli,3F4YG@33958|Lactobacillaceae 91061|Bacilli U Belongs to the purine-cytosine permease (2.A.39) family - - - - - - - - - - - - Transp_cyt_pur CCPPCCOK_00768 334390.LAF_0910 1.64e-105 305.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,3F6NT@33958|Lactobacillaceae 91061|Bacilli T GAF domain-containing protein ytsP - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 CCPPCCOK_00769 334390.LAF_0909 3.6e-122 348.0 COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,3F70T@33958|Lactobacillaceae 91061|Bacilli M Acetyltransferase (GNAT) domain ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 CCPPCCOK_00770 334390.LAF_0908 4.65e-100 290.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,3F6H4@33958|Lactobacillaceae 91061|Bacilli O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR CCPPCCOK_00771 334390.LAF_0907 7.86e-92 268.0 COG4918@1|root,COG4918@2|Bacteria,1VK6M@1239|Firmicutes,4HRFS@91061|Bacilli,3F7JD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the HesB IscA family - - - - - - - - - - - - Fe-S_biosyn CCPPCCOK_00772 334390.LAF_0906 6.53e-220 607.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,3F3PJ@33958|Lactobacillaceae 91061|Bacilli C inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 CCPPCCOK_00773 334390.LAF_0905 2.53e-123 351.0 COG3477@1|root,COG3477@2|Bacteria,1VX0K@1239|Firmicutes,4HX2R@91061|Bacilli,3F6A5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1440) - - - ko:K08996 - - - - ko00000 - - - DUF1440 CCPPCCOK_00774 334390.LAF_0904 0.0 1586.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,3F3MJ@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV CCPPCCOK_00775 334390.LAF_0903 0.0 1273.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,3F430@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim CCPPCCOK_00776 334390.LAF_0902 5.26e-134 380.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HHUW@91061|Bacilli,3FCBC@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf CCPPCCOK_00777 334390.LAF_0901 9.3e-220 605.0 COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,3F3KT@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase lacX - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim CCPPCCOK_00778 334390.LAF_0900 7.8e-199 551.0 COG4973@1|root,COG4973@2|Bacteria 2|Bacteria D DNA integration - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase CCPPCCOK_00779 334390.LAF_0899 0.0 1370.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,3F3VS@33958|Lactobacillaceae 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom CCPPCCOK_00780 334390.LAF_0898 5.14e-212 585.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,3F41U@33958|Lactobacillaceae 91061|Bacilli LU DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A CCPPCCOK_00781 334390.LAF_0897 4.82e-179 499.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,3F3JC@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII CCPPCCOK_00782 334390.LAF_0896 2.95e-206 570.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,3F3MI@33958|Lactobacillaceae 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 CCPPCCOK_00783 764291.STRUR_1162 5.17e-125 377.0 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase,Rep_3 CCPPCCOK_00784 1215915.BN193_09825 1.02e-30 110.0 29JD8@1|root,306AR@2|Bacteria,1TZGG@1239|Firmicutes,4I8QX@91061|Bacilli,1YCJV@1357|Lactococcus 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00785 1158614.I592_01957 1.57e-98 306.0 COG3620@1|root,COG3620@2|Bacteria,1TPHQ@1239|Firmicutes,4HCHD@91061|Bacilli,4B0HV@81852|Enterococcaceae 91061|Bacilli K Replication initiation factor - - - ko:K07467 - - - - ko00000 - - - HTH_3,Rep_trans CCPPCCOK_00786 1229517.AMFD01000003_gene1479 9.03e-17 81.3 COG1476@1|root,COG1476@2|Bacteria,1V00T@1239|Firmicutes,4HUAR@91061|Bacilli 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 CCPPCCOK_00787 220668.45723568 2.21e-131 374.0 COG4300@1|root,COG4300@2|Bacteria,1V1RM@1239|Firmicutes,4HGMR@91061|Bacilli,3F4RK@33958|Lactobacillaceae 91061|Bacilli P Cadmium resistance transporter cadD - - - - - - - - - - - Cad CCPPCCOK_00788 220668.45723567 4.58e-82 243.0 COG0640@1|root,COG0640@2|Bacteria,1U6UR@1239|Firmicutes,4IGNM@91061|Bacilli,3F8IK@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_20 CCPPCCOK_00789 1423814.HMPREF0549_1440 0.0 1260.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,3F5VV@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A CCPPCCOK_00790 1423814.HMPREF0549_1441 4.32e-125 357.0 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,4HHVK@91061|Bacilli,3FCFP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 CCPPCCOK_00791 1423814.HMPREF0549_1442 7.98e-274 749.0 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,4HCNN@91061|Bacilli,3F5UA@33958|Lactobacillaceae 91061|Bacilli L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 CCPPCCOK_00792 1423814.HMPREF0549_1443 3.34e-67 204.0 2A43N@1|root,30SNQ@2|Bacteria,1UFAR@1239|Firmicutes,4I4IY@91061|Bacilli,3F7I9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00793 1423814.HMPREF0549_1444 5.3e-40 132.0 2CI33@1|root,3347K@2|Bacteria,1VH48@1239|Firmicutes,4IG8B@91061|Bacilli,3F7UP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00794 1423814.HMPREF0549_1445 2.33e-103 299.0 COG1595@1|root,COG1595@2|Bacteria,1U5RP@1239|Firmicutes,4IFH3@91061|Bacilli,3F6FZ@33958|Lactobacillaceae 91061|Bacilli K DNA-templated transcription, initiation - - - - - - - - - - - - - CCPPCCOK_00795 1423814.HMPREF0549_1446 9.76e-212 585.0 2BUCV@1|root,32PNS@2|Bacteria,1U8HM@1239|Firmicutes,4IIFH@91061|Bacilli,3FAZV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00796 1423814.HMPREF0549_1447 3.42e-41 135.0 COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,4HR5J@91061|Bacilli,3F8NU@33958|Lactobacillaceae 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 CCPPCCOK_00797 1423814.HMPREF0549_1448 0.0 1034.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,3F4HM@33958|Lactobacillaceae 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase CCPPCCOK_00798 1423814.HMPREF0549_1449 4.21e-107 309.0 COG0732@1|root,COG0732@2|Bacteria,1V66H@1239|Firmicutes 1239|Firmicutes V type I restriction modification DNA specificity domain hsdS - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S CCPPCCOK_00799 1033743.CAES01000053_gene4798 1.87e-41 149.0 COG0732@1|root,COG0732@2|Bacteria,1UZGE@1239|Firmicutes,4HCYM@91061|Bacilli 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S CCPPCCOK_00800 1423814.HMPREF0549_0615 1.18e-228 630.0 COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,4HD04@91061|Bacilli,3F4GF@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase CCPPCCOK_00801 1423814.HMPREF0549_0616 9.1e-116 340.0 COG0732@1|root,COG0732@2|Bacteria,1V5F3@1239|Firmicutes,4HICD@91061|Bacilli,3F7V8@33958|Lactobacillaceae 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S CCPPCCOK_00802 1423814.HMPREF0549_1450 0.0 2034.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli,3F50Q@33958|Lactobacillaceae 91061|Bacilli V Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF3387,HSDR_N,ResIII CCPPCCOK_00803 1423814.HMPREF0549_1451 4.99e-253 692.0 COG4823@1|root,COG4823@2|Bacteria 2|Bacteria V Abi-like protein - - - - - - - - - - - - Abi_2 CCPPCCOK_00804 334390.LAF_0255 4.65e-72 216.0 COG2388@1|root,COG2388@2|Bacteria 2|Bacteria S GCN5-related N-acetyl-transferase HA62_12640 - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG CCPPCCOK_00805 334390.LAF_0256 3.55e-127 361.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,3F65D@33958|Lactobacillaceae 91061|Bacilli F dUTP diphosphatase dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase CCPPCCOK_00806 334390.LAF_0257 0.0 875.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,3F3W8@33958|Lactobacillaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI CCPPCCOK_00807 334390.LAF_0258 7.84e-264 723.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,3F46T@33958|Lactobacillaceae 91061|Bacilli S domain protein yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM CCPPCCOK_00808 334390.LAF_0259 0.0 999.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,3F3PR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c CCPPCCOK_00809 334390.LAF_0260 9.63e-130 369.0 COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,4HH6F@91061|Bacilli,3F66D@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0340 family ywlG - - - - - - - - - - - DUF436 CCPPCCOK_00810 334390.LAF_0261 0.0 938.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,3F4K7@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g CCPPCCOK_00811 334390.LAF_0262 1.25e-93 273.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,3F6HS@33958|Lactobacillaceae 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 CCPPCCOK_00812 334390.LAF_0263 1.01e-173 485.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,3F3TD@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind CCPPCCOK_00813 334390.LAF_0264 5.57e-135 382.0 COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4HAHR@91061|Bacilli 91061|Bacilli K Belongs to the sigma-70 factor family sigH - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CCPPCCOK_00814 334390.LAF_0265 7.09e-30 105.0 COG0267@1|root,COG0267@2|Bacteria,1VFTQ@1239|Firmicutes,4HR5Q@91061|Bacilli,3F83F@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 CCPPCCOK_00815 334390.LAF_0266 2.48e-32 112.0 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes 1239|Firmicutes U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE CCPPCCOK_00816 334390.LAF_0267 1.18e-126 360.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,3F55W@33958|Lactobacillaceae 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG CCPPCCOK_00817 334390.LAF_0268 3.34e-68 207.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,3F64I@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N CCPPCCOK_00818 334390.LAF_0269 1.38e-156 440.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,3F3VQ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 CCPPCCOK_00819 203120.LEUM_1077 7.45e-28 112.0 COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,4HDHP@91061|Bacilli,4AWZ3@81850|Leuconostocaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - ko:K08166 - - - - ko00000,ko02000 2.A.1.3.10 - - MFS_1 CCPPCCOK_00820 334390.LAF_0951 9.22e-96 280.0 COG0454@1|root,COG0456@2|Bacteria,1V1RG@1239|Firmicutes,4HFN7@91061|Bacilli,3F73H@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain paiA - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 CCPPCCOK_00821 334390.LAF_0950 5.23e-97 282.0 COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,4HJHJ@91061|Bacilli 91061|Bacilli O OsmC-like protein - - - ko:K07397 - - - - ko00000 - - - OsmC CCPPCCOK_00822 334390.LAF_0949 8.57e-92 269.0 COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,4HKZD@91061|Bacilli,3F73Q@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator ywnA - - - - - - - - - - - Rrf2 CCPPCCOK_00823 334390.LAF_0948 2.84e-209 579.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HESS@91061|Bacilli,3FB49@33958|Lactobacillaceae 91061|Bacilli M ABC transporter, substrate-binding protein, QAT family proWY - - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC CCPPCCOK_00824 334390.LAF_0947 1.8e-138 393.0 COG1174@1|root,COG1174@2|Bacteria,1V41S@1239|Firmicutes,4HH8U@91061|Bacilli,3FB48@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease proWZ - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 CCPPCCOK_00825 334390.LAF_0946 5.43e-180 501.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,3F55H@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran,CBS CCPPCCOK_00826 334390.LAF_0945 7.95e-132 375.0 COG1174@1|root,COG1174@2|Bacteria,1UHWH@1239|Firmicutes,4HJIP@91061|Bacilli,3F5XQ@33958|Lactobacillaceae 91061|Bacilli P ABC transporter, permease protein - - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 CCPPCCOK_00827 334390.LAF_0944 1.19e-231 637.0 COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HER3@91061|Bacilli,3F4HK@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 CCPPCCOK_00828 334390.LAF_0943 2.03e-250 687.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HABC@91061|Bacilli,3F3WG@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase bdhA - 1.1.1.14,1.1.1.264,1.1.1.303,1.1.1.4 ko:K00004,ko:K00008,ko:K00098 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 M00014 R00875,R01896,R02855,R02946,R05684,R10504 RC00085,RC00089,RC00102,RC00205,RC00525 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N CCPPCCOK_00829 334390.LAF_0942 4.21e-287 783.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CCPPCCOK_00830 334390.LAF_0941 2.4e-230 633.0 COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,4HEQ3@91061|Bacilli,3F3RA@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolase, choloylglycine hydrolase family protein yxeI - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH CCPPCCOK_00831 334390.LAF_0940 1.77e-260 713.0 COG4974@1|root,COG4974@2|Bacteria,1URNQ@1239|Firmicutes,4HEPI@91061|Bacilli,3FBHV@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family xerS - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase CCPPCCOK_00832 1138822.PL11_07740 3.78e-79 245.0 COG0679@1|root,COG0679@2|Bacteria,1VDS9@1239|Firmicutes,4HQT5@91061|Bacilli,3F5JF@33958|Lactobacillaceae 91061|Bacilli S Membrane transport protein ywkB - - ko:K07088 - - - - ko00000 - - - Mem_trans CCPPCCOK_00833 334390.LAF_0939 1.21e-229 636.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,3F4G4@33958|Lactobacillaceae 91061|Bacilli C Isocitrate/isopropylmalate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CCPPCCOK_00834 334390.LAF_0939 3.08e-45 156.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,3F4G4@33958|Lactobacillaceae 91061|Bacilli C Isocitrate/isopropylmalate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CCPPCCOK_00835 334390.LAF_0938 1.57e-194 540.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli,3F3V7@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin CCPPCCOK_00836 334390.LAF_0937 1.85e-105 305.0 COG4720@1|root,COG4720@2|Bacteria,1VBJP@1239|Firmicutes,4HNRQ@91061|Bacilli,3FB41@33958|Lactobacillaceae 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS CCPPCCOK_00837 334390.LAF_0936 1.97e-214 592.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3F3PW@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase yvgN - - - - - - - - - - - Aldo_ket_red CCPPCCOK_00838 334390.LAF_0935 1.02e-206 573.0 COG1434@1|root,COG1434@2|Bacteria,1UR34@1239|Firmicutes,4HDF2@91061|Bacilli,3F4J5@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 CCPPCCOK_00840 478749.BRYFOR_05251 1.41e-06 47.0 COG4367@1|root,COG4367@2|Bacteria,1VMC5@1239|Firmicutes,255VS@186801|Clostridia 186801|Clostridia S Uncharacterized protein conserved in bacteria (DUF2316) - - - - - - - - - - - - DUF2316 CCPPCCOK_00841 334390.LAF_0933 3.86e-124 353.0 COG0454@1|root,COG0456@2|Bacteria,1VHRC@1239|Firmicutes,4IE00@91061|Bacilli,3F6M3@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 CCPPCCOK_00842 334390.LAF_0932 1.05e-208 577.0 COG0657@1|root,COG0657@2|Bacteria,1V83G@1239|Firmicutes,4HMC4@91061|Bacilli 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 CCPPCCOK_00843 334390.LAF_0931 2.57e-151 429.0 COG2369@1|root,COG2369@2|Bacteria,1UZ30@1239|Firmicutes,4HBNN@91061|Bacilli,3FBV4@33958|Lactobacillaceae 91061|Bacilli S Phage minor capsid protein 2 - - - - - - - - - - - - Ntox50,Phage_min_cap2 CCPPCCOK_00846 334390.LAF_0929 1.89e-276 755.0 COG0436@1|root,COG0436@2|Bacteria,1TQPD@1239|Firmicutes,4HE7P@91061|Bacilli,3F3PZ@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase - - - - - - - - - - - - Aminotran_1_2 CCPPCCOK_00847 334390.LAF_0928 1.6e-235 650.0 COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HBWI@91061|Bacilli,3F5HH@33958|Lactobacillaceae 91061|Bacilli E Ornithine cyclodeaminase/mu-crystallin family - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall CCPPCCOK_00848 334390.LAF_0927 1.05e-47 164.0 COG0477@1|root,COG0477@2|Bacteria,1UHPS@1239|Firmicutes,4HD28@91061|Bacilli,3FBSX@33958|Lactobacillaceae 91061|Bacilli EGP Sugar (and other) transporter - - - ko:K08368 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr CCPPCCOK_00849 334390.LAF_0927 1.44e-174 496.0 COG0477@1|root,COG0477@2|Bacteria,1UHPS@1239|Firmicutes,4HD28@91061|Bacilli,3FBSX@33958|Lactobacillaceae 91061|Bacilli EGP Sugar (and other) transporter - - - ko:K08368 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr CCPPCCOK_00850 334390.LAF_0927 7.73e-34 127.0 COG0477@1|root,COG0477@2|Bacteria,1UHPS@1239|Firmicutes,4HD28@91061|Bacilli,3FBSX@33958|Lactobacillaceae 91061|Bacilli EGP Sugar (and other) transporter - - - ko:K08368 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr CCPPCCOK_00851 334390.LAF_0926 2.19e-124 355.0 COG0503@1|root,COG0503@2|Bacteria,1V1XS@1239|Firmicutes,4HG1T@91061|Bacilli,3F6EK@33958|Lactobacillaceae 91061|Bacilli F Phosphoribosyl transferase domain - - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran CCPPCCOK_00852 334390.LAF_0925 9.33e-96 283.0 COG3177@1|root,COG3177@2|Bacteria,1VZV8@1239|Firmicutes,4HYXN@91061|Bacilli,3F66E@33958|Lactobacillaceae 91061|Bacilli S Fic/DOC family - - - - - - - - - - - - Fic CCPPCCOK_00853 334390.LAF_0924 1.59e-111 322.0 COG0110@1|root,COG0110@2|Bacteria,1U99W@1239|Firmicutes,4HFQZ@91061|Bacilli,3FC9C@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac CCPPCCOK_00854 334390.LAF_0923 3.66e-139 394.0 COG0110@1|root,COG0110@2|Bacteria,1TQQB@1239|Firmicutes,4HG1G@91061|Bacilli,3FC9A@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase lacA - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac CCPPCCOK_00855 334390.LAF_0922 1.56e-255 699.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,3F4BD@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 CCPPCCOK_00856 334390.LAF_0921 0.0 903.0 COG0531@1|root,COG0531@2|Bacteria,1TSSB@1239|Firmicutes,4HA92@91061|Bacilli,3F5SN@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - ko:K03758 - - - - ko00000,ko02000 2.A.3.2 - - AA_permease_2 CCPPCCOK_00857 334390.LAF_1617 1.43e-21 91.3 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HEPU@91061|Bacilli,3FBIX@33958|Lactobacillaceae 91061|Bacilli S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans CCPPCCOK_00859 334390.LAF_1619 0.0 873.0 COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,3F569@33958|Lactobacillaceae 91061|Bacilli E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT - 2.6.1.19,5.1.1.21 ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 CCPPCCOK_00860 334390.LAF_1620 0.0 886.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA32@91061|Bacilli,3FCAJ@33958|Lactobacillaceae 91061|Bacilli E amino acid ctrA - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 CCPPCCOK_00861 334390.LAF_1621 1.06e-106 308.0 COG0655@1|root,COG0655@2|Bacteria,1V955@1239|Firmicutes,4IEX8@91061|Bacilli,3F4UW@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red,Flavodoxin_2 CCPPCCOK_00862 349123.Lreu23DRAFT_4480 3.59e-10 58.2 COG0655@1|root,COG0655@2|Bacteria,1V955@1239|Firmicutes,4IEX8@91061|Bacilli,3F4UW@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red,Flavodoxin_2 CCPPCCOK_00863 334390.LAF_1622 5.09e-200 553.0 COG0494@1|root,COG0824@1|root,COG0494@2|Bacteria,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli,3F7PP@33958|Lactobacillaceae 91061|Bacilli L Thioesterase-like superfamily yneP - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 CCPPCCOK_00864 862514.HMPREF0623_1380 2.74e-68 212.0 COG0110@1|root,COG0110@2|Bacteria,1TSQQ@1239|Firmicutes,4HJJ7@91061|Bacilli,3F73Z@33958|Lactobacillaceae 91061|Bacilli S transferase hexapeptide repeat - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2 CCPPCCOK_00865 334390.LAF_1624 0.0 904.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,3F4PF@33958|Lactobacillaceae 91061|Bacilli E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 CCPPCCOK_00866 334390.LAF_1625 1.18e-303 828.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,3F46X@33958|Lactobacillaceae 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth CCPPCCOK_00867 334390.LAF_1626 0.0 1211.0 COG1807@1|root,COG1807@2|Bacteria,1UYWB@1239|Firmicutes,4HTZD@91061|Bacilli,3F5AG@33958|Lactobacillaceae 1239|Firmicutes M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 CCPPCCOK_00868 334390.LAF_1627 3.78e-132 375.0 COG1309@1|root,COG1309@2|Bacteria,1VDR5@1239|Firmicutes,4HMPB@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N CCPPCCOK_00869 1035184.HMPREF1042_1541 5.02e-31 115.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,42D91@671232|Streptococcus anginosus group 91061|Bacilli V ABC transporter XK27_06785 - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CCPPCCOK_00870 334390.LAF_1628 4.99e-168 473.0 COG0624@1|root,COG3064@1|root,COG0624@2|Bacteria,COG3064@2|Bacteria,1UJIE@1239|Firmicutes,4ITAB@91061|Bacilli,3FBV7@33958|Lactobacillaceae 91061|Bacilli M Membrane - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - - CCPPCCOK_00871 334390.LAF_1629 3.45e-16 78.2 COG3976@1|root,COG3976@2|Bacteria,1VBTI@1239|Firmicutes,4HKRR@91061|Bacilli,3F7N4@33958|Lactobacillaceae 91061|Bacilli S FMN_bind - - - - - - - - - - - - FMN_bind CCPPCCOK_00872 334390.LAF_1630 0.0 1205.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein yhcA - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD CCPPCCOK_00873 334390.LAF_1631 8.31e-159 446.0 COG1309@1|root,COG1309@2|Bacteria,1UV8F@1239|Firmicutes,4I430@91061|Bacilli,3F87D@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CCPPCCOK_00874 334390.LAF_1760 0.0 991.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,3F48G@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N CCPPCCOK_00875 334390.LAF_1761 0.0 944.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,3F3S8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 CCPPCCOK_00876 334390.LAF_1762 3.03e-106 306.0 COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4HNHG@91061|Bacilli,3F4Z0@33958|Lactobacillaceae 91061|Bacilli T universal stress protein usp5 - - - - - - - - - - - Usp CCPPCCOK_00877 334390.LAF_1763 3.07e-103 298.0 COG1522@1|root,COG1522@2|Bacteria,1V3MI@1239|Firmicutes,4HJUY@91061|Bacilli,3F6FN@33958|Lactobacillaceae 91061|Bacilli K AsnC family - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type CCPPCCOK_00878 334390.LAF_1764 1.05e-177 495.0 COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,3F4N6@33958|Lactobacillaceae 91061|Bacilli IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) kduD - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 CCPPCCOK_00879 334390.LAF_1765 1.01e-230 636.0 COG1609@1|root,COG1609@2|Bacteria,1TQSY@1239|Firmicutes,4HAJI@91061|Bacilli,3F51M@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor - - - ko:K02525 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3,Peripla_BP_4 CCPPCCOK_00880 334390.LAF_1766 0.0 1177.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,3F4E5@33958|Lactobacillaceae 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N CCPPCCOK_00881 334390.LAF_1767 1.29e-298 816.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,3F4Q2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltT - - ko:K03309,ko:K11102 - - - - ko00000,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2 - iYO844.BSU10220 SDF CCPPCCOK_00882 334390.LAF_1768 1.24e-160 449.0 COG2364@1|root,COG2364@2|Bacteria,1V8E3@1239|Firmicutes,4HJ08@91061|Bacilli,3F4H9@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - CCPPCCOK_00883 1154757.Q5C_03715 3.15e-38 128.0 COG2963@1|root,COG2963@2|Bacteria,1UA5J@1239|Firmicutes,4IDAI@91061|Bacilli,4AY88@81850|Leuconostocaceae 91061|Bacilli L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 CCPPCCOK_00884 1423732.BALS01000136_gene388 0.0 1134.0 COG0277@1|root,COG0277@2|Bacteria,1UZAG@1239|Firmicutes,4H9ZB@91061|Bacilli,3F59H@33958|Lactobacillaceae 91061|Bacilli C D-lactate dehydrogenase, membrane binding dld - 1.1.5.12 ko:K03777 ko00620,ko01120,map00620,map01120 - R00704,R11591 RC00044 ko00000,ko00001,ko01000 - - - FAD_binding_4,Lact-deh-memb CCPPCCOK_00885 334390.LAF_1153 0.0 1104.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,3F3PS@33958|Lactobacillaceae 91061|Bacilli K Fibronectin-binding protein FbpA - - - - - - - - - - - DUF814,FbpA CCPPCCOK_00886 334390.LAF_1152 6.96e-206 570.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,3F40W@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV CCPPCCOK_00887 334390.LAF_1151 1.14e-128 367.0 29PI5@1|root,30AGA@2|Bacteria,1U6MD@1239|Firmicutes,4IGE8@91061|Bacilli,3F85A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00888 334390.LAF_1150 1.23e-172 482.0 COG3022@1|root,COG3022@2|Bacteria,1V5Z7@1239|Firmicutes,4HM7S@91061|Bacilli 91061|Bacilli S Belongs to the UPF0246 family yaaA - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD CCPPCCOK_00889 334390.LAF_1149 1.76e-153 431.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,3F3PN@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yagB - - ko:K06950 - - - - ko00000 - - - HD CCPPCCOK_00890 334390.LAF_1148 1.24e-146 413.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,3F521@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding ylbE - - - - - - - - - - - NAD_binding_10 CCPPCCOK_00891 334390.LAF_1147 8.44e-128 362.0 COG0454@1|root,COG0456@2|Bacteria,1VZ11@1239|Firmicutes,4HH5T@91061|Bacilli,3FBE8@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 CCPPCCOK_00892 334390.LAF_1146 4.02e-202 560.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,3F44T@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06620 GHMP_kinases_C,GHMP_kinases_N CCPPCCOK_00893 334390.LAF_1145 1.77e-298 815.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,3F5BM@33958|Lactobacillaceae 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 CCPPCCOK_00894 334390.LAF_1144 0.0 984.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli,3F3UF@33958|Lactobacillaceae 91061|Bacilli E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N CCPPCCOK_00895 334390.LAF_1143 6.93e-158 444.0 COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,4HE6G@91061|Bacilli,3F5PP@33958|Lactobacillaceae 91061|Bacilli E azaleucine resistance protein AzlC azlC - - - - - - - - - - - AzlC CCPPCCOK_00896 334390.LAF_1142 7.76e-72 216.0 COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,4HJID@91061|Bacilli,3F8HI@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid transport azlD - - - - - - - - - - - AzlD CCPPCCOK_00897 334390.LAF_1141 1.16e-72 218.0 COG0599@1|root,COG0599@2|Bacteria,1VWSB@1239|Firmicutes,4HJ1V@91061|Bacilli,3F736@33958|Lactobacillaceae 91061|Bacilli S decarboxylase yphJ - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD CCPPCCOK_00898 334390.LAF_1140 1.99e-231 639.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,3F3JK@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase E1 component pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh CCPPCCOK_00899 334390.LAF_1139 7.41e-229 630.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,3F4RV@33958|Lactobacillaceae 91061|Bacilli C Transketolase, C-terminal domain protein pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14590 Transket_pyr,Transketolase_C CCPPCCOK_00900 334390.LAF_1138 1.73e-275 757.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,3F3RR@33958|Lactobacillaceae 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding CCPPCCOK_00901 334390.LAF_1137 0.0 898.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,3F426@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase pdhD - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim CCPPCCOK_00902 334390.LAF_1136 2.88e-249 683.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,3F4UZ@33958|Lactobacillaceae 91061|Bacilli H Lipoate-protein ligase lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C CCPPCCOK_00903 334390.LAF_1135 1.23e-274 750.0 COG2755@1|root,COG2755@2|Bacteria,1UYZ1@1239|Firmicutes,4IFB2@91061|Bacilli,3F64G@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 CCPPCCOK_00904 334390.LAF_1133 2.06e-68 207.0 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HAZB@91061|Bacilli,3F3VP@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator lysR - - - - - - - - - - - HTH_1,LysR_substrate CCPPCCOK_00905 1423814.HMPREF0549_0416 5.18e-17 79.7 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HDPG@91061|Bacilli,3FC6P@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain protein rlrB - - - - - - - - - - - HTH_1,LysR_substrate CCPPCCOK_00906 334390.LAF_1131 5.38e-273 749.0 COG0477@1|root,COG2814@2|Bacteria,1TQM0@1239|Firmicutes,4HATA@91061|Bacilli,3F3SE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - ko:K08196 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,Sugar_tr CCPPCCOK_00907 334390.LAF_1130 0.0 880.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3TX@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 CCPPCCOK_00908 334390.LAF_1129 1.8e-271 745.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,3F3T5@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein mdtG2 - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,Sugar_tr CCPPCCOK_00909 908339.HMPREF9265_0247 2.64e-201 572.0 COG0477@1|root,COG2814@2|Bacteria,1VU5Q@1239|Firmicutes,4HUUP@91061|Bacilli,3F3JN@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - ko:K18934 - - - - ko00000,ko02000 2.A.1.3.39 - - MFS_1 CCPPCCOK_00910 334390.LAF_1128 1.53e-214 591.0 COG0639@1|root,COG0639@2|Bacteria,1UZK9@1239|Firmicutes,4HG1F@91061|Bacilli,3F5JR@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain prpA3 - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos_2 CCPPCCOK_00911 334390.LAF_1127 3.52e-57 177.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli,3F7KX@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 CCPPCCOK_00912 334390.LAF_1126 8.22e-305 832.0 COG1455@1|root,COG1455@2|Bacteria,1V5SI@1239|Firmicutes,4HJTK@91061|Bacilli,3F3Z5@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts13C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC CCPPCCOK_00913 334390.LAF_1125 1.52e-208 577.0 COG4814@1|root,COG4814@2|Bacteria,1V8NG@1239|Firmicutes,4HJ22@91061|Bacilli,3F41V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 CCPPCCOK_00914 334390.LAF_1124 0.0 955.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD4 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 CCPPCCOK_00915 334390.LAF_1123 0.0 1137.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,3F4AZ@33958|Lactobacillaceae 91061|Bacilli P TrkA C-terminal domain protein yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N CCPPCCOK_00916 334390.LAF_1122 4.64e-36 122.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,3F83T@33958|Lactobacillaceae 91061|Bacilli G Belongs to the 4-oxalocrotonate tautomerase family dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase CCPPCCOK_00917 334390.LAF_1121 0.0 1006.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N CCPPCCOK_00919 334390.LAF_1119 0.0 1313.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans CCPPCCOK_00920 334390.LAF_0232 3.65e-203 565.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli,3F4M2@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily hdhL - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N CCPPCCOK_00922 525309.HMPREF0494_0411 1.86e-218 607.0 COG1062@1|root,COG1062@2|Bacteria,1TP8E@1239|Firmicutes,4HAH9@91061|Bacilli,3F3QP@33958|Lactobacillaceae 91061|Bacilli C Zn-dependent alcohol dehydrogenases, class III adhC - 1.1.1.90 ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N CCPPCCOK_00923 908339.HMPREF9265_1029 3.1e-118 348.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,3F4PP@33958|Lactobacillaceae 91061|Bacilli K sugar-binding domain protein citR - - - - - - - - - - - Sugar-bind CCPPCCOK_00924 525309.HMPREF0494_0755 1.09e-169 493.0 COG1767@1|root,COG3697@1|root,COG1767@2|Bacteria,COG3697@2|Bacteria,1TQGQ@1239|Firmicutes,4HGCS@91061|Bacilli,3F4SU@33958|Lactobacillaceae 91061|Bacilli H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase citG - 2.4.2.52 ko:K05966 ko02020,map02020 - R09675 RC00049,RC00063 ko00000,ko00001,ko01000 - - - CitG,CitX CCPPCCOK_00925 1423775.BAMN01000031_gene132 8.66e-88 268.0 COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,4HMJ7@91061|Bacilli,3F4FI@33958|Lactobacillaceae 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 CCPPCCOK_00926 334390.LAF_0957 6.26e-138 390.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4IEJ7@91061|Bacilli,3F4SP@33958|Lactobacillaceae 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase CCPPCCOK_00927 334390.LAF_1118 9.2e-57 177.0 28QH1@1|root,2ZCZ3@2|Bacteria,1W1MV@1239|Firmicutes,4IG80@91061|Bacilli,3F7TZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00928 334390.LAF_1116 0.0 1853.0 COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,4HD9X@91061|Bacilli,3F4AK@33958|Lactobacillaceae 91061|Bacilli S Bacterial membrane protein YfhO yfhO - - - - - - - - - - - YfhO CCPPCCOK_00930 334390.LAF_1114 5.61e-301 825.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily lmrB - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 CCPPCCOK_00931 334390.LAF_1113 4.19e-203 562.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 CCPPCCOK_00932 334390.LAF_1112 6.38e-118 342.0 COG0702@1|root,COG0702@2|Bacteria,1V0UQ@1239|Firmicutes,4HDP4@91061|Bacilli,3FB42@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10,NmrA CCPPCCOK_00933 334390.LAF_1112 7.06e-58 186.0 COG0702@1|root,COG0702@2|Bacteria,1V0UQ@1239|Firmicutes,4HDP4@91061|Bacilli,3FB42@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10,NmrA CCPPCCOK_00934 334390.LAF_1111 1.51e-194 539.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3FC8A@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase supH - - - - - - - - - - - Hydrolase_3 CCPPCCOK_00937 334390.LAF_1110 0.0 885.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,3F4WU@33958|Lactobacillaceae 91061|Bacilli U amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 CCPPCCOK_00939 334390.LAF_1109 3.51e-273 749.0 COG2271@1|root,COG2271@2|Bacteria,1UI3V@1239|Firmicutes,4ISEV@91061|Bacilli,3F3ZF@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CCPPCCOK_00940 888816.HMPREF9389_1805 7.56e-15 70.5 COG1605@1|root,COG1605@2|Bacteria,1VK50@1239|Firmicutes,4HPQX@91061|Bacilli,1WRX6@1305|Streptococcus sanguinis 91061|Bacilli E Chorismate mutase aroH - 5.4.99.5 ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 CCPPCCOK_00941 334390.LAF_1108 4.62e-273 748.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,3F502@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt CCPPCCOK_00942 334390.LAF_1107 4.48e-131 371.0 2E0PE@1|root,32W87@2|Bacteria,1VC0E@1239|Firmicutes,4HKI6@91061|Bacilli,3F60R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00943 334390.LAF_1106 3.33e-302 825.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,3F5B2@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase CCPPCCOK_00944 334390.LAF_1105 1.67e-250 688.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,3F589@33958|Lactobacillaceae 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH CCPPCCOK_00945 334390.LAF_1104 2.15e-116 333.0 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli,3F7FE@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI CCPPCCOK_00946 334390.LAF_1103 9.06e-279 762.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HF8A@91061|Bacilli,3F4FA@33958|Lactobacillaceae 91061|Bacilli E DegT/DnrJ/EryC1/StrS aminotransferase family aspB3 - - - - - - - - - - - Aminotran_1_2 CCPPCCOK_00947 334390.LAF_1102 2.41e-235 647.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,3F4US@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C CCPPCCOK_00948 334390.LAF_1101 2.2e-227 627.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt CCPPCCOK_00949 334390.LAF_1100 1.1e-201 560.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA CCPPCCOK_00950 334390.LAF_1099 1.25e-31 110.0 29PXD@1|root,30AVR@2|Bacteria,1U75W@1239|Firmicutes,4IH0H@91061|Bacilli,3F90N@33958|Lactobacillaceae 91061|Bacilli S Virus attachment protein p12 family - - - - - - - - - - - - P12 CCPPCCOK_00951 334390.LAF_1098 0.0 1275.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,3F553@33958|Lactobacillaceae 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate CCPPCCOK_00952 334390.LAF_1097 2e-45 146.0 COG1918@1|root,COG1918@2|Bacteria,1U69I@1239|Firmicutes,4IG0P@91061|Bacilli,3F7DB@33958|Lactobacillaceae 91061|Bacilli P FeoA domain feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA CCPPCCOK_00953 334390.LAF_1096 2.3e-186 518.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,3F3XT@33958|Lactobacillaceae 91061|Bacilli O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran CCPPCCOK_00954 334390.LAF_1095 7.7e-312 849.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,3F4BR@33958|Lactobacillaceae 91061|Bacilli O FeS assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 CCPPCCOK_00955 334390.LAF_1094 2.6e-298 813.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,3F3UP@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 CCPPCCOK_00956 334390.LAF_1093 2.5e-109 314.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,3F6WP@33958|Lactobacillaceae 91061|Bacilli C SUF system FeS assembly protein, NifU family nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N CCPPCCOK_00957 334390.LAF_1092 0.0 936.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,3F44I@33958|Lactobacillaceae 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 CCPPCCOK_00958 334390.LAF_1091 4.72e-242 666.0 COG0614@1|root,COG0614@2|Bacteria,1V1B8@1239|Firmicutes,4I2JG@91061|Bacilli,3F3R5@33958|Lactobacillaceae 91061|Bacilli P Periplasmic binding protein fecB - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 CCPPCCOK_00960 585524.HMPREF0493_1289 0.0 1246.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copB - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 - - E1-E2_ATPase,Hydrolase CCPPCCOK_00961 1154757.Q5C_01510 7.39e-98 284.0 COG3682@1|root,COG3682@2|Bacteria,1VA7Q@1239|Firmicutes,4HKGF@91061|Bacilli,4AXUN@81850|Leuconostocaceae 91061|Bacilli K Transcriptional regulator atkY - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R CCPPCCOK_00962 1291743.LOSG293_360110 2.54e-132 376.0 COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,4HCFF@91061|Bacilli,3F429@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed pinR1 - - - - - - - - - - - HTH_7,Resolvase CCPPCCOK_00963 334390.LAF_1784 1.75e-151 426.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,3F4RP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CCPPCCOK_00964 334390.LAF_1785 3.46e-225 623.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,3F3K5@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease yxeA - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CCPPCCOK_00965 405566.lhv_1961 3.81e-187 528.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli,3FC6T@33958|Lactobacillaceae 91061|Bacilli C Pyridine nucleotide-disulfide oxidoreductase - - 1.8.1.7 ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CCPPCCOK_00966 913848.AELK01000222_gene2364 8.4e-56 174.0 COG1813@1|root,COG1813@2|Bacteria,1VEXE@1239|Firmicutes,4HQ33@91061|Bacilli,3F816@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 CCPPCCOK_00967 1201292.DR75_1741 2.45e-42 153.0 28P3D@1|root,2ZBZ3@2|Bacteria,1V1XD@1239|Firmicutes,4HGF1@91061|Bacilli,4B3NH@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - EcsC CCPPCCOK_00968 575594.ACOH01000006_gene337 1.88e-90 282.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,3F4RB@33958|Lactobacillaceae 91061|Bacilli L PFAM Transposase, IS204 IS1001 IS1096 IS1165 - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 CCPPCCOK_00969 575594.ACOH01000029_gene637 8.34e-101 292.0 arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli,3F6T7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00970 334390.LAF_0675 3.35e-89 269.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve CCPPCCOK_00971 334390.LAF_0394 1.8e-76 228.0 COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,4HIMF@91061|Bacilli,3F719@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF956) manO - - - - - - - - - - - DUF956 CCPPCCOK_00972 334390.LAF_0393 1.37e-219 605.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA CCPPCCOK_00973 334390.LAF_0392 2.38e-164 462.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,3F3V5@33958|Lactobacillaceae 91061|Bacilli G PTS system manY - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor CCPPCCOK_00974 334390.LAF_0391 1.82e-230 635.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli,3F4PU@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component manL - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb CCPPCCOK_00975 334390.LAF_0390 1.5e-231 636.0 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli,3F45Z@33958|Lactobacillaceae 91061|Bacilli P Peroxidase ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal CCPPCCOK_00976 334390.LAF_0389 8.77e-117 334.0 COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,4HPH8@91061|Bacilli,3F6W4@33958|Lactobacillaceae 91061|Bacilli K Domain of unknown function (DUF1836) - - - - - - - - - - - - DUF1836 CCPPCCOK_00977 334390.LAF_0388 7.71e-192 533.0 COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,4HC4E@91061|Bacilli,3FBEP@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family yitS - - - - - - - - - - - DegV CCPPCCOK_00978 1423814.HMPREF0549_0419 3.15e-163 465.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,3F40I@33958|Lactobacillaceae 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI CCPPCCOK_00979 334390.LAF_0387 6.02e-216 596.0 COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,4HDGS@91061|Bacilli,3FBIA@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CCPPCCOK_00980 334390.LAF_0386 6.96e-222 614.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,4HCCP@91061|Bacilli,3F4TY@33958|Lactobacillaceae 91061|Bacilli S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 CCPPCCOK_00981 334390.LAF_0385 4.69e-106 310.0 COG1388@1|root,COG1388@2|Bacteria,1VA10@1239|Firmicutes,4HMUH@91061|Bacilli,3FC14@33958|Lactobacillaceae 91061|Bacilli M Lysin motif lytE - - - - - - - - - - - LysM CCPPCCOK_00982 334390.LAF_0384 2.13e-193 536.0 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HGA9@91061|Bacilli,3FC89@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase XK27_02985 - - - - - - - - - - - Hydrolase_3 CCPPCCOK_00983 575594.ACOH01000010_gene1642 3.35e-262 739.0 COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,3F3WT@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Acyl_transf_3 CCPPCCOK_00984 334390.LAF_0383 4.4e-69 208.0 2C26E@1|root,3424N@2|Bacteria,1VX4A@1239|Firmicutes,4HXT9@91061|Bacilli,3F70Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_00985 334390.LAF_0382 0.0 1173.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,3F467@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS CCPPCCOK_00986 334390.LAF_0381 0.0 874.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,3F3W5@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CCPPCCOK_00987 334390.LAF_0380 2.4e-151 432.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,3F41C@33958|Lactobacillaceae 91061|Bacilli S YbbR-like protein ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR CCPPCCOK_00988 334390.LAF_0379 1.61e-192 535.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,3F4N3@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N CCPPCCOK_00989 334390.LAF_0378 2.34e-212 587.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,3F40T@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C CCPPCCOK_00990 334390.LAF_0377 4e-133 376.0 COG0847@1|root,COG0847@2|Bacteria,1V57H@1239|Firmicutes,4HI1V@91061|Bacilli,3F42Z@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T CCPPCCOK_00991 334390.LAF_0376 5.51e-118 337.0 COG0454@1|root,COG0456@2|Bacteria,1V22A@1239|Firmicutes,4ITA6@91061|Bacilli,3F7BU@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 CCPPCCOK_00992 334390.LAF_0375 4.21e-105 303.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,3F3MR@33958|Lactobacillaceae 91061|Bacilli O Hydrolase, P-loop family ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE CCPPCCOK_00993 334390.LAF_0374 9.74e-229 630.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,3F3MW@33958|Lactobacillaceae 91061|Bacilli C phosphate acetyltransferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB CCPPCCOK_00994 334390.LAF_0373 4.52e-175 486.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,3F3W0@33958|Lactobacillaceae 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG CCPPCCOK_00995 334390.LAF_0372 2.36e-139 393.0 COG4894@1|root,COG4894@2|Bacteria,1V8EY@1239|Firmicutes,4HMMS@91061|Bacilli,3F698@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - LOR CCPPCCOK_00996 334390.LAF_0371 4.66e-110 316.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,3F65B@33958|Lactobacillaceae 91061|Bacilli J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB CCPPCCOK_00997 334390.LAF_0370 0.0 1532.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,3F4EC@33958|Lactobacillaceae 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 CCPPCCOK_00998 334390.LAF_0369 6.82e-46 148.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,3F7IQ@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG CCPPCCOK_00999 334390.LAF_0368 0.0 1000.0 COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F3MU@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC CCPPCCOK_01000 334390.LAF_0367 0.0 877.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yifK - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease CCPPCCOK_01001 334390.LAF_0366 0.0 865.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,3F3JP@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N CCPPCCOK_01002 334390.LAF_0365 2.92e-184 512.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,3F494@33958|Lactobacillaceae 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM CCPPCCOK_01003 334390.LAF_0364 4.22e-287 784.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,3F3SC@33958|Lactobacillaceae 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK CCPPCCOK_01004 334390.LAF_0363 1.31e-244 671.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,3F3JS@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N CCPPCCOK_01005 334390.LAF_0362 3.82e-23 88.2 29PH2@1|root,30AF7@2|Bacteria,1U6K5@1239|Firmicutes,4IGCV@91061|Bacilli,3F82T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01006 908339.HMPREF9265_0592 4.67e-28 110.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli,3F5JW@33958|Lactobacillaceae 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - HTH_38,rve CCPPCCOK_01007 557436.Lreu_1002 7.89e-85 256.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli,3F5JW@33958|Lactobacillaceae 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - HTH_38,rve CCPPCCOK_01008 1158601.I585_02874 5.17e-38 132.0 COG0110@1|root,COG0110@2|Bacteria,1V56K@1239|Firmicutes,4HTPS@91061|Bacilli,4B54E@81852|Enterococcaceae 91061|Bacilli S Maltose acetyltransferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac CCPPCCOK_01009 334390.LAF_1531 1.49e-154 434.0 COG1514@1|root,COG1514@2|Bacteria,1VEKU@1239|Firmicutes,4I0FI@91061|Bacilli,3F6IQ@33958|Lactobacillaceae 91061|Bacilli J 2'-5' RNA ligase superfamily - - - - - - - - - - - - 2_5_RNA_ligase2 CCPPCCOK_01010 334390.LAF_1530 5.89e-171 477.0 COG3382@1|root,COG3382@2|Bacteria,1TT38@1239|Firmicutes,4HCE2@91061|Bacilli,3F4C9@33958|Lactobacillaceae 91061|Bacilli S B3 4 domain XK27_07210 - - - - - - - - - - - B3_4 CCPPCCOK_01011 334390.LAF_1528 1.37e-247 679.0 COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli,3F4PR@33958|Lactobacillaceae 91061|Bacilli C alcohol dehydrogenase adhP - 1.1.1.1 ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CCPPCCOK_01012 1138822.PL11_10705 3.8e-31 113.0 COG2963@1|root,COG2963@2|Bacteria,1V6PN@1239|Firmicutes,4HK4K@91061|Bacilli,3F5S2@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - ko:K07483,ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - HTH_28,HTH_Tnp_1,Terminase_5 CCPPCCOK_01013 1138822.PL11_10700 2.18e-215 594.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HBHG@91061|Bacilli,3F59Y@33958|Lactobacillaceae 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - HTH_21,HTH_28,rve,rve_2 CCPPCCOK_01014 797515.HMPREF9103_02020 2.43e-98 288.0 COG3247@1|root,COG3247@2|Bacteria,1V759@1239|Firmicutes,4HK5F@91061|Bacilli,3F58J@33958|Lactobacillaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 CCPPCCOK_01015 334390.LAF_1460 0.0 910.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase npr - 1.11.1.1 ko:K05910 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CCPPCCOK_01016 349123.Lreu23DRAFT_3295 9.11e-81 255.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 CCPPCCOK_01017 1423790.BN53_00815 4.51e-71 224.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 CCPPCCOK_01018 1138822.PL11_10515 3.66e-237 655.0 COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,4HEW7@91061|Bacilli,3F4CJ@33958|Lactobacillaceae 91061|Bacilli P Citrate transporter ysdE - - - - - - - - - - - CitMHS CCPPCCOK_01019 334390.LAF_1615 0.0 879.0 COG1249@1|root,COG1249@2|Bacteria,1VTHV@1239|Firmicutes,4HV84@91061|Bacilli,3FC6U@33958|Lactobacillaceae 91061|Bacilli C pyridine nucleotide-disulfide oxidoreductase - - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2 CCPPCCOK_01020 334390.LAF_1616 5.57e-70 211.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F6Y3@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin CCPPCCOK_01021 334390.LAF_1617 9.14e-155 439.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HEPU@91061|Bacilli,3FBIX@33958|Lactobacillaceae 91061|Bacilli S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans CCPPCCOK_01022 334390.LAF_1660 1.46e-315 898.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,3F3Y3@33958|Lactobacillaceae 91061|Bacilli V domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 CCPPCCOK_01023 334390.LAF_1661 4.94e-121 346.0 COG1309@1|root,COG1309@2|Bacteria,1VEM5@1239|Firmicutes,4HQRV@91061|Bacilli,3F66Z@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator (TetR family) - - - - - - - - - - - - TetR_C_8,TetR_N CCPPCCOK_01024 334390.LAF_1662 1.61e-250 687.0 COG2017@1|root,COG2017@2|Bacteria,1V5UK@1239|Firmicutes,4HTRY@91061|Bacilli,3FC7G@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim CCPPCCOK_01025 334390.LAF_1663 5.54e-214 591.0 2C6F0@1|root,32RH8@2|Bacteria,1V7ET@1239|Firmicutes,4HJDI@91061|Bacilli,3F4UC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01026 334390.LAF_1664 7.65e-10 62.0 2EQI3@1|root,33I43@2|Bacteria,1VN2E@1239|Firmicutes,4HR4S@91061|Bacilli,3F860@33958|Lactobacillaceae 91061|Bacilli - - - - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - - CCPPCCOK_01027 334390.LAF_1665 7.28e-110 315.0 COG0735@1|root,COG0735@2|Bacteria,1V6RI@1239|Firmicutes,4HIGM@91061|Bacilli,3F6W3@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Fur family zur - - ko:K02076,ko:K03711 - - - - ko00000,ko03000 - - - FUR CCPPCCOK_01028 334390.LAF_1666 9.61e-137 387.0 COG0194@1|root,COG0194@2|Bacteria,1V8PW@1239|Firmicutes,4HJCB@91061|Bacilli,3F6N3@33958|Lactobacillaceae 91061|Bacilli F Guanylate kinase gmk2 - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin CCPPCCOK_01029 334390.LAF_1667 8.97e-95 276.0 COG1051@1|root,COG1051@2|Bacteria,1VED7@1239|Firmicutes,4HRPV@91061|Bacilli,3FBDM@33958|Lactobacillaceae 91061|Bacilli F Nudix hydrolase - - - - - - - - - - - - NUDIX CCPPCCOK_01030 944562.HMPREF9102_1688 4.03e-261 724.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid yhdG - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 CCPPCCOK_01031 334390.LAF_1668 0.0 1617.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli,3F44E@33958|Lactobacillaceae 91061|Bacilli E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 CCPPCCOK_01033 1423807.BACO01000023_gene708 6.21e-21 93.2 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 CCPPCCOK_01034 575594.ACOH01000006_gene171 1.99e-83 263.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F587@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC CCPPCCOK_01035 257314.LJ_0440 3.82e-36 134.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F587@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC CCPPCCOK_01036 1158607.UAU_00434 3.18e-197 557.0 COG0240@1|root,COG0240@2|Bacteria,1TUSI@1239|Firmicutes,4IUWZ@91061|Bacilli,4B4E0@81852|Enterococcaceae 91061|Bacilli C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain - - - - - - - - - - - - Octopine_DH CCPPCCOK_01037 334390.LAF_0920 1.96e-151 429.0 COG1794@1|root,COG1794@2|Bacteria,1V2G1@1239|Firmicutes,4HK0S@91061|Bacilli 91061|Bacilli M racemase activity, acting on amino acids and derivatives - - - - - - - - - - - - Asp_Glu_race CCPPCCOK_01038 1045004.OKIT_0514 7.17e-162 453.0 COG3316@1|root,COG3316@2|Bacteria,1TTKR@1239|Firmicutes,4HCB4@91061|Bacilli,4AXG2@81850|Leuconostocaceae 91061|Bacilli L DDE domain tnp1216 - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 CCPPCCOK_01039 557436.Lreu_0067 9.26e-317 864.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase nox - 1.6.3.4 ko:K17869 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CCPPCCOK_01040 525318.HMPREF0497_1559 3.8e-65 206.0 COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,4HDX2@91061|Bacilli,3F51V@33958|Lactobacillaceae 91061|Bacilli L Resolvase, N terminal domain tnpR1 GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - - - - - - - - - - Resolvase CCPPCCOK_01041 334390.LAF_1568 9e-29 110.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,3F43M@33958|Lactobacillaceae 91061|Bacilli L hmm pf00665 - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve CCPPCCOK_01042 334390.LAF_1772 6.91e-156 437.0 COG0108@1|root,COG0108@2|Bacteria,1U24A@1239|Firmicutes,4IBMV@91061|Bacilli,3F4KE@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase CCPPCCOK_01044 1605.Lani381_1372 1.36e-270 762.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli,3F3P7@33958|Lactobacillaceae 91061|Bacilli G Transporter lacS - - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 CCPPCCOK_01045 349123.Lreu23DRAFT_5164 5.57e-103 312.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator lacR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 CCPPCCOK_01046 1400520.LFAB_12875 1.61e-57 190.0 COG5434@1|root,COG5434@2|Bacteria,1TQXN@1239|Firmicutes,4HBHT@91061|Bacilli,3F4Y5@33958|Lactobacillaceae 91061|Bacilli M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 CCPPCCOK_01048 334390.LAF_1011 1.17e-273 748.0 COG1835@1|root,COG1835@2|Bacteria,1V7GP@1239|Firmicutes,4HJ4R@91061|Bacilli,3F42R@33958|Lactobacillaceae 91061|Bacilli I transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - Acyl_transf_3 CCPPCCOK_01050 1423754.BALY01000017_gene387 1.26e-120 345.0 COG3479@1|root,COG3479@2|Bacteria,1UY0X@1239|Firmicutes,4HAN3@91061|Bacilli,3F4P4@33958|Lactobacillaceae 91061|Bacilli Q Phenolic acid decarboxylase padC - - ko:K13727 - - - - ko00000,ko01000 - - - PA_decarbox CCPPCCOK_01051 334390.LAF_1009 5.05e-128 363.0 COG1695@1|root,COG1695@2|Bacteria,1V5J2@1239|Firmicutes,4IPMM@91061|Bacilli,3FBD5@33958|Lactobacillaceae 91061|Bacilli K Virulence activator alpha C-term - - - - - - - - - - - - PadR,Vir_act_alpha_C CCPPCCOK_01052 334390.LAF_1008 3.37e-104 300.0 COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,3F68C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the NDK family ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK CCPPCCOK_01053 324831.LGAS_1628 6.92e-56 182.0 COG0398@1|root,COG0398@2|Bacteria,1V6V7@1239|Firmicutes,4HITM@91061|Bacilli,3F417@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc CCPPCCOK_01054 334390.LAF_1006 7.83e-304 827.0 COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli,3F47M@33958|Lactobacillaceae 91061|Bacilli N Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG CCPPCCOK_01055 334390.LAF_1005 0.0 1176.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,3F4RN@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C CCPPCCOK_01057 334390.LAF_1003 0.0 886.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yifK - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease CCPPCCOK_01059 334390.LAF_1000 0.0 922.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepDA - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 CCPPCCOK_01060 334390.LAF_0999 3.89e-209 578.0 COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli,3F3Y8@33958|Lactobacillaceae 91061|Bacilli F DNA RNA non-specific endonuclease endA - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2,Endonuclease_NS CCPPCCOK_01061 334390.LAF_0998 4.23e-213 588.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,3F4SY@33958|Lactobacillaceae 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N CCPPCCOK_01062 334390.LAF_0997 0.0 1555.0 COG1502@1|root,COG1502@2|Bacteria,1V3AR@1239|Firmicutes,4HWUN@91061|Bacilli,3F53M@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - - - - - - - - - - RE_NgoFVII CCPPCCOK_01063 334390.LAF_0996 5.3e-207 572.0 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,3F5UB@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 CCPPCCOK_01065 334390.LAF_0994 1.13e-290 793.0 29QI4@1|root,30BHJ@2|Bacteria,1U84T@1239|Firmicutes,4II28@91061|Bacilli,3FAIY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01066 334390.LAF_0993 1.17e-249 685.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase flp - - - - - - - - - - - Beta-lactamase,SLH CCPPCCOK_01067 334390.LAF_0992 2.02e-117 335.0 COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,3F6QT@33958|Lactobacillaceae 91061|Bacilli I Phosphatidylglycerophosphatase A pgpA - - - - - - - - - - - PgpA CCPPCCOK_01068 334390.LAF_0991 5.11e-160 450.0 COG0730@1|root,COG0730@2|Bacteria,1V75K@1239|Firmicutes,4HEE8@91061|Bacilli,3F6BU@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE CCPPCCOK_01069 334390.LAF_0990 3.14e-237 655.0 COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,4HGFS@91061|Bacilli,3F603@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter XK27_12525 - - - - - - - - - - - AI-2E_transport CCPPCCOK_01070 334390.LAF_0989 2.68e-273 748.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,3F3Q5@33958|Lactobacillaceae 91061|Bacilli I Belongs to the thiolase family atoB - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red,Thiolase_C,Thiolase_N CCPPCCOK_01071 334390.LAF_0988 3.46e-207 572.0 COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,4HCHJ@91061|Bacilli,3F52H@33958|Lactobacillaceae 91061|Bacilli S Phospholipase, patatin family rssA - - - - - - - - - - - Patatin CCPPCCOK_01072 334390.LAF_0987 1.11e-213 591.0 COG0583@1|root,COG0583@2|Bacteria,1V3HS@1239|Firmicutes,4IQPW@91061|Bacilli,3F4HP@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CCPPCCOK_01073 334390.LAF_0986 0.0 1202.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,3F53U@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind,FMN_red,Shikimate_dh_N CCPPCCOK_01074 334390.LAF_0984 4.39e-109 321.0 2DPC1@1|root,331GC@2|Bacteria,1VE35@1239|Firmicutes,4HMP3@91061|Bacilli,3F66X@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4352) - - - - - - - - - - - - DUF4352 CCPPCCOK_01076 334390.LAF_0983 7.63e-146 414.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F5NA@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family yicL - - - - - - - - - - - EamA CCPPCCOK_01077 334390.LAF_0982 2.18e-83 246.0 2E6DR@1|root,3311A@2|Bacteria,1U5WC@1239|Firmicutes,4IFK0@91061|Bacilli,3F6MC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - bPH_5 CCPPCCOK_01079 525309.HMPREF0494_0068 1.8e-185 523.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli,3FC6T@33958|Lactobacillaceae 91061|Bacilli C Pyridine nucleotide-disulfide oxidoreductase - - 1.8.1.7 ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CCPPCCOK_01082 334390.LAF_0224 0.0 997.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,3F439@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon CCPPCCOK_01083 334390.LAF_0223 2.17e-241 663.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,3F4C6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus CCPPCCOK_01084 334390.LAF_0222 3.89e-208 575.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,3F42B@33958|Lactobacillaceae 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 CCPPCCOK_01085 334390.LAF_0221 0.0 1263.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,3F49Z@33958|Lactobacillaceae 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 CCPPCCOK_01086 334390.LAF_0220 5.21e-126 358.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,3F56C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran CCPPCCOK_01087 334390.LAF_0219 0.0 887.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,3F4GY@33958|Lactobacillaceae 91061|Bacilli J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C CCPPCCOK_01088 334390.LAF_0218 1.65e-113 326.0 COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,3F6HV@33958|Lactobacillaceae 91061|Bacilli J RNA binding yabR - - ko:K07571 - - - - ko00000 - - - S1 CCPPCCOK_01089 334390.LAF_0217 5.88e-74 222.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC CCPPCCOK_01090 334390.LAF_0216 2.47e-53 167.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,3F7JX@33958|Lactobacillaceae 91061|Bacilli J S4 domain protein yabO - - - - - - - - - - - S4 CCPPCCOK_01091 334390.LAF_0215 0.0 2276.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,3F4KU@33958|Lactobacillaceae 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF CCPPCCOK_01092 334390.LAF_0214 7.98e-132 374.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,3F3VZ@33958|Lactobacillaceae 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro CCPPCCOK_01093 334390.LAF_0213 4.51e-148 417.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,3F3JY@33958|Lactobacillaceae 91061|Bacilli S (CBS) domain - - - - - - - - - - - - CBS CCPPCCOK_01094 334390.LAF_0212 3.51e-75 225.0 COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,4HGXF@91061|Bacilli,3F6Y9@33958|Lactobacillaceae 91061|Bacilli L Toxic component of a toxin-antitoxin (TA) module ndoA - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin CCPPCCOK_01095 334390.LAF_0211 6.25e-268 733.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,3F3X2@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N CCPPCCOK_01096 334390.LAF_0210 3.39e-78 233.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,3F6HC@33958|Lactobacillaceae 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS CCPPCCOK_01097 334390.LAF_0209 0.0 892.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,3F46Q@33958|Lactobacillaceae 91061|Bacilli F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C CCPPCCOK_01098 334390.LAF_0208 0.0 902.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,3F4SK@33958|Lactobacillaceae 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CCPPCCOK_01099 334390.LAF_0207 1.9e-202 561.0 COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,3F40Z@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 CCPPCCOK_01100 334390.LAF_0206 4.76e-119 341.0 COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,4HH6H@91061|Bacilli,3F4TF@33958|Lactobacillaceae 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA CCPPCCOK_01101 1203076.CAKF01000021_gene1543 2.59e-61 192.0 COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli,3F74A@33958|Lactobacillaceae 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc CCPPCCOK_01102 334390.LAF_0205 5.38e-158 444.0 COG3764@1|root,COG3764@2|Bacteria,1V83Z@1239|Firmicutes,4HJV9@91061|Bacilli,3F54V@33958|Lactobacillaceae 91061|Bacilli M sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase CCPPCCOK_01103 1203076.CAKF01000021_gene1512 1.59e-37 137.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9UE@91061|Bacilli,3FCA7@33958|Lactobacillaceae 91061|Bacilli EGP MFS_1 like family pmrA - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr CCPPCCOK_01104 334390.LAF_0204 3.85e-55 171.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HKF0@91061|Bacilli,3F7D7@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 CCPPCCOK_01105 334390.LAF_0203 4.36e-302 824.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,3F3P8@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase CCPPCCOK_01106 334390.LAF_0202 0.0 1066.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,3F42X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase CCPPCCOK_01107 334390.LAF_0201 1.95e-68 212.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,3F55D@33958|Lactobacillaceae 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH CCPPCCOK_01108 334390.LAF_0200 5.23e-97 282.0 COG4506@1|root,COG4506@2|Bacteria,1V8IZ@1239|Firmicutes,4HIW0@91061|Bacilli,3F6AI@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1934) ywiB - - - - - - - - - - - DUF1934 CCPPCCOK_01109 334390.LAF_0199 0.0 921.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,3F442@33958|Lactobacillaceae 91061|Bacilli S HD domain protein ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD CCPPCCOK_01110 334390.LAF_0198 1.01e-184 514.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase yidA - - - - - - - - - - - Hydrolase_3 CCPPCCOK_01111 334390.LAF_0197 1.89e-78 243.0 29P09@1|root,309YE@2|Bacteria,1U5XS@1239|Firmicutes,4IFM1@91061|Bacilli,3F6NK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01112 334390.LAF_0196 4.45e-227 626.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3U2@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N CCPPCCOK_01113 334390.LAF_0195 9.91e-302 826.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,3F4I3@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase CCPPCCOK_01114 334390.LAF_0194 2.13e-193 537.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,3F3NH@33958|Lactobacillaceae 91061|Bacilli F pur operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N CCPPCCOK_01115 334390.LAF_0193 3.99e-166 467.0 COG1108@1|root,COG1108@2|Bacteria,1V0SX@1239|Firmicutes,4HTE9@91061|Bacilli,3FC75@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family - - - ko:K02075 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 CCPPCCOK_01116 334390.LAF_0192 5.68e-123 351.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,3F49M@33958|Lactobacillaceae 91061|Bacilli P ABC transporter adcC - - ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 M00242,M00244,M00319 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran CCPPCCOK_01117 334390.LAF_0191 3.61e-213 589.0 COG0803@1|root,COG0803@2|Bacteria,1V110@1239|Firmicutes,4HZ7G@91061|Bacilli,3FBJR@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA - - ko:K02077,ko:K11707 ko02010,map02010 M00244,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA CCPPCCOK_01118 334390.LAF_0190 4.04e-205 567.0 COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,3F43W@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.29 - iYO844.BSU00460 GHMP_kinases_C,GHMP_kinases_N CCPPCCOK_01119 334390.LAF_0189 6.18e-206 570.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,3F3VC@33958|Lactobacillaceae 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD CCPPCCOK_01120 334390.LAF_0188 3.77e-127 362.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,3F64F@33958|Lactobacillaceae 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 CCPPCCOK_01121 334390.LAF_0187 3.29e-189 525.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,3F3N2@33958|Lactobacillaceae 91061|Bacilli L hydrolase, TatD family tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase CCPPCCOK_01122 334390.LAF_0186 0.0 1333.0 COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,3F3XR@33958|Lactobacillaceae 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind CCPPCCOK_01123 334390.LAF_0185 5.76e-208 574.0 COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,4HA0X@91061|Bacilli,3F40Y@33958|Lactobacillaceae 91061|Bacilli F Protein of unknown function DUF72 yunF - - - - - - - - - - - DUF72 CCPPCCOK_01124 334390.LAF_0184 2.38e-272 746.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,3F4X1@33958|Lactobacillaceae 91061|Bacilli EGP transporter blt - - ko:K08153 - M00717 - - ko00000,ko00002,ko02000 2.A.1.2.8 - - MFS_1 CCPPCCOK_01125 334390.LAF_0183 2.31e-165 462.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HC4I@91061|Bacilli,3F4WS@33958|Lactobacillaceae 91061|Bacilli K SIR2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 CCPPCCOK_01126 334390.LAF_0182 6.18e-238 654.0 296WI@1|root,2ZU5A@2|Bacteria,1VT7R@1239|Firmicutes,4HVBN@91061|Bacilli,3F4R1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01127 334390.LAF_0181 9.58e-287 785.0 COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli,3F3YY@33958|Lactobacillaceae 91061|Bacilli C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red CCPPCCOK_01128 334390.LAF_0180 7.95e-222 612.0 COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,3F3SR@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA CCPPCCOK_01129 334390.LAF_0179 0.0 1494.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase - - - - - - - - - - - - AAA_19,UvrD_C_2 CCPPCCOK_01130 334390.LAF_0178 1.28e-258 711.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,3F3QK@33958|Lactobacillaceae 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family napA - - - - - - - - - - - Na_H_Exchanger CCPPCCOK_01131 334390.LAF_0177 9.46e-199 551.0 COG1464@1|root,COG1464@2|Bacteria,1V0Z6@1239|Firmicutes,4HBBW@91061|Bacilli,3FC6K@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family metQ1 - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 CCPPCCOK_01132 1138822.PL11_10715 2.96e-17 79.7 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve CCPPCCOK_01133 525309.HMPREF0494_0090 7.83e-65 203.0 COG1476@1|root,COG1476@2|Bacteria,1U63F@1239|Firmicutes,4IFSU@91061|Bacilli,3F6Y5@33958|Lactobacillaceae 91061|Bacilli K TRANSCRIPTIONal - - - - - - - - - - - - HTH_3 CCPPCCOK_01134 1423807.BACO01000056_gene1651 4.46e-35 148.0 COG3203@1|root,COG4932@1|root,COG3203@2|Bacteria,COG4932@2|Bacteria,1VXP5@1239|Firmicutes,4HWZF@91061|Bacilli,3F5AT@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - DUF1542,Gram_pos_anchor,MucBP CCPPCCOK_01135 97137.C821_01777 1.82e-53 198.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - G5,Gram_pos_anchor,YSIRK_signal CCPPCCOK_01136 97137.C821_01777 1.16e-38 154.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - G5,Gram_pos_anchor,YSIRK_signal CCPPCCOK_01137 944562.HMPREF9102_0624 1.95e-110 324.0 COG1556@1|root,COG1556@2|Bacteria,1UZAK@1239|Firmicutes,4HH3R@91061|Bacilli,3F4UV@33958|Lactobacillaceae 91061|Bacilli S LUD domain lutC - - ko:K00782 - - - - ko00000 - - - LUD_dom CCPPCCOK_01138 944562.HMPREF9102_0625 1.52e-307 845.0 COG1139@1|root,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,3F4IV@33958|Lactobacillaceae 91061|Bacilli C 4Fe-4S dicluster domain lutB - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom CCPPCCOK_01139 908339.HMPREF9265_0021 2.76e-155 439.0 COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,3F4GX@33958|Lactobacillaceae 91061|Bacilli C Cysteine-rich domain lutA - - ko:K18928 - - - - ko00000 - - - CCG CCPPCCOK_01140 334390.LAF_0707 2.21e-276 756.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli,3F425@33958|Lactobacillaceae 91061|Bacilli I Hydroxymethylglutaryl-CoA synthase mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N CCPPCCOK_01141 334390.LAF_0708 4.36e-149 419.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3F3JG@33958|Lactobacillaceae 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 CCPPCCOK_01142 334390.LAF_0709 1.97e-49 157.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,3F87S@33958|Lactobacillaceae 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 CCPPCCOK_01143 1203076.CAKF01000010_gene212 1.22e-35 122.0 COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HKMJ@91061|Bacilli,3F809@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0154) XK26_06720 - - ko:K09976 - - - - ko00000 - - - UPF0154 CCPPCCOK_01144 334390.LAF_0711 3.06e-150 422.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,3F4QB@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase CCPPCCOK_01145 334390.LAF_0712 6.86e-176 490.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,3F4C5@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase small domain yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS CCPPCCOK_01146 334390.LAF_0713 2.67e-62 191.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,3F7G2@33958|Lactobacillaceae 91061|Bacilli L GIY-YIG catalytic domain protein yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG CCPPCCOK_01147 334390.LAF_0714 3.14e-181 504.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3F3M1@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 CCPPCCOK_01148 334390.LAF_0715 4.14e-198 550.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,3F459@33958|Lactobacillaceae 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS CCPPCCOK_01149 334390.LAF_0716 1.38e-166 466.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,3F42J@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase CCPPCCOK_01150 334390.LAF_0717 6.51e-122 348.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,3F4X2@33958|Lactobacillaceae 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF CCPPCCOK_01151 334390.LAF_0718 2.7e-185 514.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,3F42M@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf CCPPCCOK_01152 334390.LAF_0719 1.17e-173 486.0 COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,4IV81@91061|Bacilli,3F4AF@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 CCPPCCOK_01153 334390.LAF_0720 8.02e-294 803.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,3F3TM@33958|Lactobacillaceae 91061|Bacilli M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 CCPPCCOK_01154 334390.LAF_0721 0.0 1132.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,3F44A@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit CCPPCCOK_01155 334390.LAF_0722 0.0 2830.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,3F4AN@33958|Lactobacillaceae 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon CCPPCCOK_01156 334390.LAF_0723 1.55e-273 748.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli,3F52J@33958|Lactobacillaceae 91061|Bacilli E acetylornithine argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 CCPPCCOK_01157 334390.LAF_0724 5.88e-176 490.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4HH91@91061|Bacilli,3F5QN@33958|Lactobacillaceae 91061|Bacilli F Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase CCPPCCOK_01158 334390.LAF_0725 6.06e-265 728.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,3F433@33958|Lactobacillaceae 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ CCPPCCOK_01159 334390.LAF_0726 8.62e-252 690.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,3F5DZ@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC CCPPCCOK_01160 334390.LAF_0727 6.19e-264 722.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase CCPPCCOK_01161 334390.LAF_0728 0.0 1982.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS CCPPCCOK_01162 334390.LAF_0729 8.99e-109 313.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,3F6GZ@33958|Lactobacillaceae 91061|Bacilli J Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C CCPPCCOK_01163 334390.LAF_0730 1.92e-282 773.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,3F3KZ@33958|Lactobacillaceae 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 CCPPCCOK_01164 334390.LAF_0731 5.27e-64 195.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,3F7E2@33958|Lactobacillaceae 91061|Bacilli K Protein of unknown function (DUF448) ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 CCPPCCOK_01165 334390.LAF_0732 9.14e-66 200.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,3F7ZK@33958|Lactobacillaceae 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae CCPPCCOK_01166 334390.LAF_0733 0.0 1347.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,3F3JV@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N CCPPCCOK_01167 334390.LAF_0734 4.99e-76 227.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,3F6WZ@33958|Lactobacillaceae 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA CCPPCCOK_01168 334390.LAF_0735 3.22e-214 591.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,3F3NX@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N CCPPCCOK_01169 334390.LAF_0736 5.91e-233 640.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,3F3TG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase CCPPCCOK_01170 334390.LAF_0737 9e-317 864.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F3XY@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily - - - - - - - - - - - - MFS_1 CCPPCCOK_01171 334390.LAF_0851 2.86e-215 594.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,3F3QR@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE CCPPCCOK_01172 334390.LAF_0852 6.13e-233 642.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,3F4F7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase CCPPCCOK_01173 334390.LAF_0853 0.0 900.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 CCPPCCOK_01174 334390.LAF_0854 0.0 872.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,3F3VJ@33958|Lactobacillaceae 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC CCPPCCOK_01175 334390.LAF_0855 6.39e-115 335.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,3F3U0@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep CCPPCCOK_01176 334390.LAF_0856 1.15e-280 766.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,3F419@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CCPPCCOK_01177 334390.LAF_0857 8.96e-223 614.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,3F4UH@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CCPPCCOK_01178 334390.LAF_0858 5.43e-182 506.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,3F3MA@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N CCPPCCOK_01179 334390.LAF_0859 9.79e-278 760.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspC - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CCPPCCOK_01180 334390.LAF_0860 1.28e-253 695.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,3F4S9@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC CCPPCCOK_01181 334390.LAF_0861 8.31e-294 805.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,3F5BE@33958|Lactobacillaceae 91061|Bacilli P Potassium uptake protein ktrB - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH CCPPCCOK_01182 334390.LAF_0862 2.79e-151 426.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,3F5G0@33958|Lactobacillaceae 91061|Bacilli P domain protein ktrA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N CCPPCCOK_01183 334390.LAF_0863 3.4e-163 457.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,3F4GT@33958|Lactobacillaceae 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK CCPPCCOK_01184 334390.LAF_0864 4.2e-202 558.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,3F3ZD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 CCPPCCOK_01185 334390.LAF_0865 1.07e-302 825.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,3F45V@33958|Lactobacillaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 CCPPCCOK_01187 334390.LAF_0867 0.0 2132.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,3F4AM@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon CCPPCCOK_01188 334390.LAF_0868 0.0 925.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,3F3JU@33958|Lactobacillaceae 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C CCPPCCOK_01189 334390.LAF_0869 1.04e-213 590.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,3F44W@33958|Lactobacillaceae 91061|Bacilli S S1 domain yitL - - ko:K00243 - - - - ko00000 - - - S1_2 CCPPCCOK_01190 334390.LAF_0870 2.98e-175 492.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae 91061|Bacilli D recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase CCPPCCOK_01191 334390.LAF_0871 2.23e-89 261.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,3F7QC@33958|Lactobacillaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1 CCPPCCOK_01192 334390.LAF_0872 1.18e-182 508.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,3F4FS@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA CCPPCCOK_01193 334390.LAF_0873 3.2e-131 373.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,3F5RN@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB CCPPCCOK_01194 334390.LAF_0874 1.68e-167 468.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,3F402@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CCPPCCOK_01195 334390.LAF_0875 2.37e-111 322.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,3F4HD@33958|Lactobacillaceae 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt CCPPCCOK_01196 334390.LAF_0876 3.83e-254 697.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HJ71@91061|Bacilli,3F45N@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain - - - - - - - - - - - - HTH_40 CCPPCCOK_01197 334390.LAF_0877 0.0 956.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind CCPPCCOK_01198 334390.LAF_0878 4.37e-76 233.0 COG1388@1|root,COG1388@2|Bacteria,1VFEU@1239|Firmicutes,4HNW5@91061|Bacilli,3F6WV@33958|Lactobacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM CCPPCCOK_01199 334390.LAF_0879 2.29e-153 431.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,3F3W4@33958|Lactobacillaceae 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin CCPPCCOK_01200 334390.LAF_0880 4.63e-275 754.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,3F4DQ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 CCPPCCOK_01201 334390.LAF_0881 8.67e-312 850.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,3F4V0@33958|Lactobacillaceae 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 CCPPCCOK_01202 334390.LAF_0882 2.65e-53 167.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,3F6YN@33958|Lactobacillaceae 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding CCPPCCOK_01203 334390.LAF_0883 2.52e-300 819.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,3F3ND@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat protein XK27_05225 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 CCPPCCOK_01204 334390.LAF_0884 1.29e-211 585.0 COG4974@1|root,COG4974@2|Bacteria,1UFH8@1239|Firmicutes,4IES1@91061|Bacilli,3F3KV@33958|Lactobacillaceae 91061|Bacilli L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_1,Phage_int_SAM_4 CCPPCCOK_01205 334390.LAF_0885 1.07e-284 778.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,3F3VH@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 CCPPCCOK_01206 334390.LAF_0886 0.0 1210.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,3FC7W@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn CCPPCCOK_01207 334390.LAF_0887 5.32e-244 668.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,3F3SB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt CCPPCCOK_01208 334390.LAF_0888 4.4e-122 347.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,3F6Y4@33958|Lactobacillaceae 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 CCPPCCOK_01209 334390.LAF_0889 8.06e-141 398.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,3F578@33958|Lactobacillaceae 91061|Bacilli S protein, hemolysin III hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII CCPPCCOK_01210 334390.LAF_0890 1.34e-197 548.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli,3F4CW@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family WQ51_01275 - - - - - - - - - - - DegV CCPPCCOK_01211 334390.LAF_0891 1.69e-277 759.0 COG0111@1|root,COG0111@2|Bacteria,1VTK3@1239|Firmicutes,4HUCI@91061|Bacilli,3F4XV@33958|Lactobacillaceae 91061|Bacilli EH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT_4 CCPPCCOK_01212 334390.LAF_0892 1.4e-145 410.0 COG0110@1|root,COG0110@2|Bacteria,1TPKX@1239|Firmicutes,4HF6J@91061|Bacilli,3F4PX@33958|Lactobacillaceae 91061|Bacilli S Bacterial transferase hexapeptide (six repeats) cat - 2.3.1.79 ko:K00661,ko:K18234 - - - - ko00000,ko01000,ko01504 - - - Hexapep,Hexapep_2 CCPPCCOK_01213 334390.LAF_0893 2.46e-217 600.0 COG2755@1|root,COG2755@2|Bacteria,1V76B@1239|Firmicutes,4HGIN@91061|Bacilli,3FBFD@33958|Lactobacillaceae 91061|Bacilli E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 CCPPCCOK_01214 334390.LAF_0894 2.85e-135 383.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli,3F5K5@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2140) ypmS - - - - - - - - - - - DUF2140 CCPPCCOK_01215 334390.LAF_0895 2.1e-49 156.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,3FCDP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like CCPPCCOK_01216 220668.45723560 4.28e-81 240.0 COG0640@1|root,COG0640@2|Bacteria,1VAMP@1239|Firmicutes,4HNAJ@91061|Bacilli,3FB51@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 CCPPCCOK_01217 220668.45723561 1.55e-79 236.0 2DMHQ@1|root,32RMG@2|Bacteria,1VB95@1239|Firmicutes,4HKKS@91061|Bacilli,3F6S7@33958|Lactobacillaceae 91061|Bacilli S Arsenical resistance operon trans-acting repressor ArsD - - - - - - - - - - - - ArsD CCPPCCOK_01218 334390.LAF_1827 4.04e-111 326.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HVQZ@91061|Bacilli,3FC44@33958|Lactobacillaceae 91061|Bacilli E Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N CCPPCCOK_01219 334390.LAF_1826 3.73e-137 388.0 COG1309@1|root,COG1309@2|Bacteria,1V4D3@1239|Firmicutes,4HJ8Z@91061|Bacilli,3F6ZM@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CCPPCCOK_01220 334390.LAF_1825 5.49e-207 577.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,3F3K5@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease yxeA - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CCPPCCOK_01221 334390.LAF_1824 2.34e-153 431.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,3F4RP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CCPPCCOK_01222 334390.LAF_1823 7.5e-100 290.0 COG1438@1|root,COG1438@2|Bacteria,1VA3U@1239|Firmicutes,4HPCQ@91061|Bacilli,3F65K@33958|Lactobacillaceae 91061|Bacilli K Regulates arginine biosynthesis genes argR - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C CCPPCCOK_01223 334390.LAF_1821 1.02e-60 187.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,3F7DH@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, ArsR family czrA - - ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 CCPPCCOK_01224 334390.LAF_1820 9.41e-315 879.0 COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,3F4XJ@33958|Lactobacillaceae 91061|Bacilli NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - 3.2.1.17 ko:K01185,ko:K02395,ko:K19223 - - - - ko00000,ko01000,ko01002,ko01011,ko02035 - CBM50 - Glucosaminidase,LysM CCPPCCOK_01225 334390.LAF_1819 4.26e-218 603.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,3F4JE@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family scrR - - ko:K02529,ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CCPPCCOK_01226 334390.LAF_1818 1.11e-35 121.0 29A0B@1|root,2ZX1X@2|Bacteria,1W51D@1239|Firmicutes,4I0QW@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01227 334390.LAF_1817 4.83e-138 391.0 29DQI@1|root,300NC@2|Bacteria,1U55V@1239|Firmicutes,4IEX6@91061|Bacilli,3F4UQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01228 334390.LAF_1816 6.55e-126 358.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F422@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C CCPPCCOK_01229 334390.LAF_1815 3.04e-140 397.0 COG0062@1|root,COG0062@2|Bacteria,1V9F4@1239|Firmicutes,4IS4H@91061|Bacilli,3F5N4@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX nnrE - 5.1.99.6 ko:K17759 - - - - ko00000,ko01000 - - - YjeF_N CCPPCCOK_01230 334390.LAF_1814 7.49e-74 221.0 2CCD8@1|root,348YF@2|Bacteria,1VZZV@1239|Firmicutes,4HZ8C@91061|Bacilli,3F79R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01231 334390.LAF_1813 2.32e-161 451.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HIR3@91061|Bacilli,3F6XY@33958|Lactobacillaceae 91061|Bacilli S Flavodoxin-like fold yrkL - - - - - - - - - - - Flavodoxin_2 CCPPCCOK_01233 334390.LAF_1811 1.36e-85 251.0 COG3189@1|root,COG3189@2|Bacteria,1VABH@1239|Firmicutes,4HKI2@91061|Bacilli,3F715@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function, DUF488 yeaO - - - - - - - - - - - DUF488 CCPPCCOK_01234 334390.LAF_1810 2e-150 422.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HG5E@91061|Bacilli,3F59D@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA glycosylase MPG family yxlJ GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco CCPPCCOK_01235 334390.LAF_1809 1.35e-261 718.0 COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,4HCYD@91061|Bacilli,3F53Z@33958|Lactobacillaceae 91061|Bacilli S associated with various cellular activities - - - - - - - - - - - - AAA_5 CCPPCCOK_01236 334390.LAF_1808 2.5e-270 741.0 COG3864@1|root,COG3864@2|Bacteria,1VE6N@1239|Firmicutes,4HMSF@91061|Bacilli,3F556@33958|Lactobacillaceae 91061|Bacilli S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N CCPPCCOK_01237 334390.LAF_1807 1.41e-59 184.0 2DKRV@1|root,30AIZ@2|Bacteria,1U6RG@1239|Firmicutes,4IGIW@91061|Bacilli,3F8D1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01238 334390.LAF_1806 3e-291 798.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease CCPPCCOK_01239 334390.LAF_1805 0.0 1273.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F4CX@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N CCPPCCOK_01240 334390.LAF_1804 2.44e-120 343.0 COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,4HIHC@91061|Bacilli,3F6GV@33958|Lactobacillaceae 91061|Bacilli S Macro domain protein ymdB - - - - - - - - - - - Macro CCPPCCOK_01241 334390.LAF_1803 1.02e-186 521.0 COG3201@1|root,COG3201@2|Bacteria,1VE5T@1239|Firmicutes,4HMNW@91061|Bacilli,3F3MB@33958|Lactobacillaceae 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter CCPPCCOK_01242 334390.LAF_1802 2.57e-104 302.0 COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,4HW8H@91061|Bacilli,3F6ZK@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N CCPPCCOK_01243 334390.LAF_1801 7.01e-216 597.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,3F4Z6@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C CCPPCCOK_01244 334390.LAF_1800 9.08e-71 213.0 2905K@1|root,2ZMVG@2|Bacteria,1W304@1239|Firmicutes,4I0TS@91061|Bacilli,3F7TH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01245 334390.LAF_1799 1.09e-180 504.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,3F4MH@33958|Lactobacillaceae 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family tcyA - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 CCPPCCOK_01246 334390.LAF_1798 3.51e-154 434.0 COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,4HV4G@91061|Bacilli,3FC59@33958|Lactobacillaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component - - - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 CCPPCCOK_01247 334390.LAF_1797 8.36e-174 484.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4HUHS@91061|Bacilli,3F4YF@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein - - - ko:K10010 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.10,3.A.1.3.14 - - ABC_tran CCPPCCOK_01248 334390.LAF_1796 1.21e-48 154.0 2930D@1|root,2ZQHQ@2|Bacteria,1W6D0@1239|Firmicutes,4HZS5@91061|Bacilli,3F7KZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01249 334390.LAF_1795 1.41e-124 354.0 COG1881@1|root,COG1881@2|Bacteria,1VJEE@1239|Firmicutes,4IRQB@91061|Bacilli,3FBPI@33958|Lactobacillaceae 91061|Bacilli S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP CCPPCCOK_01250 334390.LAF_1794 8.31e-186 516.0 COG2365@1|root,COG2365@2|Bacteria,1V851@1239|Firmicutes,4HJB2@91061|Bacilli,3F55V@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 CCPPCCOK_01251 334390.LAF_1793 1.2e-234 644.0 COG2755@1|root,COG2755@2|Bacteria,1U9HW@1239|Firmicutes,4HQ3R@91061|Bacilli,3F4VR@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase family celE3 - - - - - - - - - - - Lipase_GDSL_2 CCPPCCOK_01252 334390.LAF_1792 2.95e-285 778.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli,3F3Q9@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg CCPPCCOK_01253 334390.LAF_1791 0.0 988.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli,3F4D8@33958|Lactobacillaceae 91061|Bacilli G UDP-glucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf CCPPCCOK_01254 334390.LAF_1790 3.16e-234 645.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 CCPPCCOK_01255 1203076.CAKF01000020_gene1643 0.0 1101.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase rafA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase CCPPCCOK_01256 1203076.CAKF01000020_gene1644 0.0 978.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli,3F3P7@33958|Lactobacillaceae 91061|Bacilli G Transporter lacS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 CCPPCCOK_01257 334390.LAF_0492 1.57e-260 715.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli,3F3V2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase CCPPCCOK_01258 334390.LAF_0491 9.28e-277 761.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HBI6@91061|Bacilli,3F57Q@33958|Lactobacillaceae 91061|Bacilli EG GntP family permease yojA - - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease CCPPCCOK_01259 1302286.BAOT01000074_gene2202 1.02e-174 491.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve CCPPCCOK_01260 334390.LAF_1025 2.15e-131 373.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - - - - - - - - - - GerE,HTH_23,Sigma70_r2,Sigma70_r4 CCPPCCOK_01262 353496.LBU_0995 0.0 1630.0 COG1061@1|root,COG1061@2|Bacteria,1U2DR@1239|Firmicutes,4HBX2@91061|Bacilli,3F4F5@33958|Lactobacillaceae 91061|Bacilli L Type III restriction enzyme, res subunit - - - - - - - - - - - - Eco57I,ResIII,T5orf172 CCPPCCOK_01263 891391.LAC30SC_05200 3.28e-76 236.0 COG0286@1|root,COG0286@2|Bacteria,1V86D@1239|Firmicutes,4HJKH@91061|Bacilli,3F7IT@33958|Lactobacillaceae 91061|Bacilli V site-specific DNA-methyltransferase (adenine-specific) activity - - - - - - - - - - - - N6_Mtase CCPPCCOK_01265 334390.LAF_1022 0.0 1100.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli,3FCE6@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family alsS - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CCPPCCOK_01266 334390.LAF_1021 7.47e-148 416.0 COG4619@1|root,COG4619@2|Bacteria,1V3DQ@1239|Firmicutes,4HHGU@91061|Bacilli,3F4UY@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ybbL - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran CCPPCCOK_01267 334390.LAF_1020 1.08e-170 478.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,3F4P1@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 CCPPCCOK_01268 334390.LAF_1019 1.47e-116 333.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,3F69R@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator, MerR family rmeB - - - - - - - - - - - MerR_1 CCPPCCOK_01269 1121914.AUDW01000007_gene604 1.63e-60 198.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,3WE6M@539002|Bacillales incertae sedis 91061|Bacilli C NADH:flavin oxidoreductase / NADH oxidase family yrfB - - - - - - - - - - - Oxidored_FMN CCPPCCOK_01270 334390.LAF_1018 4.53e-98 288.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3F4E3@33958|Lactobacillaceae 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ1 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD CCPPCCOK_01271 334390.LAF_1017 1.89e-74 224.0 COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,4HH49@91061|Bacilli,3F7YV@33958|Lactobacillaceae 91061|Bacilli T Low molecular weight phosphotyrosine protein phosphatase arsC - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc CCPPCCOK_01273 334390.LAF_1015 2.4e-277 758.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 CCPPCCOK_01274 334390.LAF_1014 0.0 899.0 COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,4HBV3@91061|Bacilli,3F4YC@33958|Lactobacillaceae 91061|Bacilli F Amidohydrolase family guaD - 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - Amidohydro_1 CCPPCCOK_01275 525309.HMPREF0494_0121 3.56e-218 605.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HABC@91061|Bacilli,3F3WG@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase tdh - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N CCPPCCOK_01276 525309.HMPREF0494_0536 5.61e-41 137.0 COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HMY5@91061|Bacilli,3F7IR@33958|Lactobacillaceae 91061|Bacilli S Sugar efflux transporter for intercellular exchange ygbF - - - - - - - - - - - MtN3_slv CCPPCCOK_01277 1133569.AHYZ01000032_gene816 1.2e-43 144.0 COG3093@1|root,COG3093@2|Bacteria,1VCFB@1239|Firmicutes,4IG6K@91061|Bacilli,3F7RE@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins axe - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 CCPPCCOK_01280 334390.LAF_1013 9.7e-60 194.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4H9M3@91061|Bacilli,3F4AH@33958|Lactobacillaceae 91061|Bacilli EK Aminotransferase, class I aadAT - - ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000 - - - Aminotran_1_2 CCPPCCOK_01281 334390.LAF_1013 3.68e-202 564.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4H9M3@91061|Bacilli,3F4AH@33958|Lactobacillaceae 91061|Bacilli EK Aminotransferase, class I aadAT - - ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000 - - - Aminotran_1_2 CCPPCCOK_01282 797515.HMPREF9103_01675 5.55e-101 307.0 COG2918@1|root,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,3F506@33958|Lactobacillaceae 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshAB - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase CCPPCCOK_01283 525309.HMPREF0494_0430 9.84e-56 189.0 COG2918@1|root,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,3F506@33958|Lactobacillaceae 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshAB - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase CCPPCCOK_01284 334390.LAF_1012 8.93e-185 515.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HD16@91061|Bacilli,3F9BQ@33958|Lactobacillaceae 91061|Bacilli ET Bacterial periplasmic substrate-binding proteins artP - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CCPPCCOK_01285 543734.LCABL_29970 5.28e-79 255.0 COG2865@1|root,COG2865@2|Bacteria,1UYYR@1239|Firmicutes,4HHVE@91061|Bacilli,3F7XH@33958|Lactobacillaceae 91061|Bacilli K Putative DNA-binding domain - - - - - - - - - - - - AlbA_2 CCPPCCOK_01286 334390.LAF_1469 0.0 910.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F41R@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_2 - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr CCPPCCOK_01287 334390.LAF_1470 2.52e-237 653.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,3F447@33958|Lactobacillaceae 91061|Bacilli G Lipid kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat CCPPCCOK_01288 334390.LAF_1471 0.0 940.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,3F44H@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey CCPPCCOK_01289 334390.LAF_1472 0.0 933.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,3F4BK@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase CCPPCCOK_01290 334390.LAF_1473 9.93e-65 197.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,3F7XB@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln CCPPCCOK_01291 334390.LAF_1474 1.94e-233 646.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,3F3KI@33958|Lactobacillaceae 91061|Bacilli S sex pheromone camS - - - - - - - - - - - CamS CCPPCCOK_01292 334390.LAF_1475 0.0 1316.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,3F43C@33958|Lactobacillaceae 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 CCPPCCOK_01293 334390.LAF_1476 0.0 1439.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C CCPPCCOK_01294 334390.LAF_1477 7.47e-280 765.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4HJI4@91061|Bacilli,3FC8U@33958|Lactobacillaceae 91061|Bacilli F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purK2 - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp CCPPCCOK_01295 334390.LAF_1478 3.89e-132 375.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,3F49S@33958|Lactobacillaceae 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran CCPPCCOK_01296 334390.LAF_1479 2.33e-142 402.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli,3F584@33958|Lactobacillaceae 91061|Bacilli NU mannosyl-glycoprotein acmA - 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,SH3_8,YceG CCPPCCOK_01297 334390.LAF_1480 4.28e-178 496.0 COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli,3F4FH@33958|Lactobacillaceae 91061|Bacilli IQ reductase budC - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 CCPPCCOK_01298 334390.LAF_1481 1.03e-263 722.0 COG3021@1|root,COG3021@2|Bacteria,1UJID@1239|Firmicutes,4ITAA@91061|Bacilli,3FBV6@33958|Lactobacillaceae 91061|Bacilli S interspecies interaction between organisms - - - - - - - - - - - - Exo_endo_phos CCPPCCOK_01299 334390.LAF_1482 2.78e-85 251.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,3F656@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 CCPPCCOK_01300 334390.LAF_1483 5.57e-104 300.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,3F696@33958|Lactobacillaceae 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 CCPPCCOK_01301 334390.LAF_1484 8.08e-188 521.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,3F4KC@33958|Lactobacillaceae 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 CCPPCCOK_01302 334390.LAF_1485 1.6e-178 498.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,3F3UW@33958|Lactobacillaceae 91061|Bacilli U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ CCPPCCOK_01303 334390.LAF_1486 1.19e-200 556.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,3F48E@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran CCPPCCOK_01304 334390.LAF_1487 5.03e-192 533.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,3F3VD@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran CCPPCCOK_01305 334390.LAF_1488 1.02e-80 239.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,3F6GJ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 CCPPCCOK_01306 334390.LAF_1489 3.48e-217 600.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,3F3W6@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L CCPPCCOK_01307 334390.LAF_1490 8.02e-84 248.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,3F67D@33958|Lactobacillaceae 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 CCPPCCOK_01308 334390.LAF_1491 1.32e-76 229.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,3F6GN@33958|Lactobacillaceae 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 CCPPCCOK_01309 334390.LAF_1492 6.38e-20 79.7 COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,3F8TC@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 CCPPCCOK_01310 334390.LAF_1493 1.69e-45 146.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,3F7CW@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a CCPPCCOK_01311 334390.LAF_1494 2.16e-156 438.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,3F3KB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid CCPPCCOK_01312 334390.LAF_1495 7.83e-301 822.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,3F4FV@33958|Lactobacillaceae 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY CCPPCCOK_01313 334390.LAF_1496 3.5e-92 270.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,3F675@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A CCPPCCOK_01314 334390.LAF_1497 6.96e-33 114.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,3F7ZU@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 CCPPCCOK_01315 334390.LAF_1498 3.59e-113 325.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,3F3VY@33958|Lactobacillaceae 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C CCPPCCOK_01316 334390.LAF_1499 5.55e-75 224.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,3F6KN@33958|Lactobacillaceae 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p CCPPCCOK_01317 334390.LAF_1500 2.05e-121 347.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,3F4G5@33958|Lactobacillaceae 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 CCPPCCOK_01318 334390.LAF_1501 2.19e-87 257.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,3F64E@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 CCPPCCOK_01319 334390.LAF_1502 2.46e-40 132.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,3FB5M@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 CCPPCCOK_01320 334390.LAF_1503 1.75e-123 352.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,3F3Q7@33958|Lactobacillaceae 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C CCPPCCOK_01321 334390.LAF_1504 1.28e-65 199.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3F6X5@33958|Lactobacillaceae 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 CCPPCCOK_01322 334390.LAF_1505 2.55e-79 236.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,3F6GT@33958|Lactobacillaceae 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 CCPPCCOK_01323 334390.LAF_1506 4.48e-55 172.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,3F7FX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 CCPPCCOK_01324 334390.LAF_1507 1.35e-38 129.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,3F82Z@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 CCPPCCOK_01325 334390.LAF_1508 2.78e-98 285.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,3F653@33958|Lactobacillaceae 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 CCPPCCOK_01326 334390.LAF_1509 3.43e-156 438.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,3F3Q8@33958|Lactobacillaceae 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C CCPPCCOK_01327 334390.LAF_1510 2.63e-71 215.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,3F6K6@33958|Lactobacillaceae 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 CCPPCCOK_01328 334390.LAF_1511 1.51e-62 191.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,3F6XP@33958|Lactobacillaceae 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 CCPPCCOK_01329 334390.LAF_1512 3.32e-203 562.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,3F3XI@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C CCPPCCOK_01330 334390.LAF_1513 2.76e-60 186.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,3F6Z2@33958|Lactobacillaceae 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 CCPPCCOK_01331 334390.LAF_1514 3.16e-137 389.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,3F3QD@33958|Lactobacillaceae 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 CCPPCCOK_01332 334390.LAF_1515 5.89e-153 430.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,3F45I@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 CCPPCCOK_01333 334390.LAF_1516 3.14e-66 201.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,3F6KC@33958|Lactobacillaceae 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 CCPPCCOK_01334 334390.LAF_1517 0.0 1358.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,3F3JR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 CCPPCCOK_01335 334390.LAF_1518 4.15e-108 311.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,3F3RX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 CCPPCCOK_01336 334390.LAF_1519 3.58e-93 272.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,3F64B@33958|Lactobacillaceae 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 CCPPCCOK_01337 1203076.CAKF01000019_gene1273 2.5e-40 144.0 COG1989@1|root,COG1989@2|Bacteria 2|Bacteria NOU aspartic-type endopeptidase activity pilD - 3.4.23.43 ko:K02236,ko:K02506,ko:K02654 - M00331,M00429 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 CCPPCCOK_01338 334390.LAF_1520 2.13e-275 754.0 2DSXT@1|root,32UTZ@2|Bacteria,1VRBZ@1239|Firmicutes,4HT22@91061|Bacilli,3F4NM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF998 CCPPCCOK_01339 334390.LAF_1521 2.92e-173 483.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,3F4PK@33958|Lactobacillaceae 91061|Bacilli S peptidase C26 puuD - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 CCPPCCOK_01340 334390.LAF_1522 0.0 2387.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,3F3KF@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 CCPPCCOK_01341 334390.LAF_1523 0.0 2357.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,3F4ET@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 CCPPCCOK_01342 334390.LAF_1525 2e-135 384.0 COG1309@1|root,COG1309@2|Bacteria,1UYPI@1239|Firmicutes,4IQ2E@91061|Bacilli,3FBFF@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CCPPCCOK_01343 334390.LAF_1526 0.0 1583.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR CCPPCCOK_01344 334390.LAF_1527 6.36e-103 298.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli,3F53E@33958|Lactobacillaceae 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR CCPPCCOK_01345 525309.HMPREF0494_1999 2.33e-10 64.7 2DI2W@1|root,33GVK@2|Bacteria,1VQCC@1239|Firmicutes,4HR7Z@91061|Bacilli,3F8BF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01347 334390.LAF_0417 1.55e-74 223.0 2FI40@1|root,349WT@2|Bacteria,1W08C@1239|Firmicutes,4HYGC@91061|Bacilli,3F7QX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01349 334390.LAF_0416 1.4e-168 471.0 COG3527@1|root,COG3527@2|Bacteria,1V4AH@1239|Firmicutes,4HJ98@91061|Bacilli,3F41S@33958|Lactobacillaceae 91061|Bacilli H Belongs to the alpha-acetolactate decarboxylase family budA - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy CCPPCCOK_01350 334390.LAF_0415 4.49e-185 514.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,3F494@33958|Lactobacillaceae 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM CCPPCCOK_01351 334390.LAF_0414 9.18e-206 568.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3FB4T@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase yvgN - - - - - - - - - - - Aldo_ket_red CCPPCCOK_01352 334390.LAF_0413 1.27e-158 445.0 COG5549@1|root,COG5549@2|Bacteria,1VW9X@1239|Firmicutes,4HWF8@91061|Bacilli,3F60X@33958|Lactobacillaceae 91061|Bacilli O PFAM peptidase M10A and M12B, matrixin and adamalysin XK27_08875 - - - - - - - - - - - Peptidase_M10 CCPPCCOK_01353 334390.LAF_0412 1.74e-111 320.0 COG0454@1|root,COG0456@2|Bacteria,1V6S5@1239|Firmicutes,4HJJY@91061|Bacilli,3F6HM@33958|Lactobacillaceae 91061|Bacilli K GNAT family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 CCPPCCOK_01355 334390.LAF_1059 7.16e-163 456.0 COG2181@1|root,COG2181@2|Bacteria,1UY97@1239|Firmicutes,4HD9W@91061|Bacilli,3F52F@33958|Lactobacillaceae 91061|Bacilli C Nitrate reductase narI - 1.7.5.1 ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Nitrate_red_gam CCPPCCOK_01356 334390.LAF_1060 2.15e-132 376.0 COG2180@1|root,COG2180@2|Bacteria,1V268@1239|Firmicutes,4HG0T@91061|Bacilli,3F4YH@33958|Lactobacillaceae 91061|Bacilli C Nitrate reductase delta subunit narJ - - ko:K00373 ko02020,map02020 - - - ko00000,ko00001 - - - Nitrate_red_del CCPPCCOK_01357 334390.LAF_1061 0.0 1088.0 COG1140@1|root,COG1140@2|Bacteria,1UJIB@1239|Firmicutes,4ITA8@91061|Bacilli,3FB9T@33958|Lactobacillaceae 91061|Bacilli C 4Fe-4S dicluster domain - - 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Fer4_11,Nitr_red_bet_C CCPPCCOK_01358 334390.LAF_1062 0.0 2551.0 COG5013@1|root,COG5013@2|Bacteria,1TQG1@1239|Firmicutes,4HBVB@91061|Bacilli,3F4JA@33958|Lactobacillaceae 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narZ - 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Molybdopterin,Molydop_binding,Nitr_red_alph_N CCPPCCOK_01359 334390.LAF_1063 6.23e-244 669.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,3F56D@33958|Lactobacillaceae 91061|Bacilli H ThiF family moeB - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF CCPPCCOK_01360 334390.LAF_1064 2.18e-112 323.0 COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,4HH5V@91061|Bacilli,3F6GI@33958|Lactobacillaceae 91061|Bacilli H May be involved in the biosynthesis of molybdopterin moaB - 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth CCPPCCOK_01361 334390.LAF_1065 8.99e-295 804.0 COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,4HAFT@91061|Bacilli,3F3Y6@33958|Lactobacillaceae 91061|Bacilli H MoeA N-terminal region (domain I and II) moeA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N CCPPCCOK_01362 334390.LAF_1066 1.11e-107 318.0 COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,4HH39@91061|Bacilli,3F65H@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC CCPPCCOK_01363 334390.LAF_1067 7.14e-128 363.0 COG0746@1|root,COG0746@2|Bacteria,1U2FC@1239|Firmicutes,4HJTM@91061|Bacilli,3F6DN@33958|Lactobacillaceae 91061|Bacilli H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 CCPPCCOK_01364 334390.LAF_1068 6.94e-54 169.0 29PC2@1|root,30AAA@2|Bacteria,1U6E2@1239|Firmicutes,4IG5X@91061|Bacilli,3F7PK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01365 334390.LAF_1069 1.74e-101 293.0 COG2203@1|root,COG2203@2|Bacteria,1VDHW@1239|Firmicutes,4HMEN@91061|Bacilli,3FBV5@33958|Lactobacillaceae 91061|Bacilli T GAF domain nreA - - ko:K10851 ko02020,map02020 - - - ko00000,ko00001 - - - GAF_2 CCPPCCOK_01366 334390.LAF_1070 3.93e-233 644.0 COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,4HAUU@91061|Bacilli,3F3XQ@33958|Lactobacillaceae 91061|Bacilli F Sensor histidine kinase nreB - 2.7.13.3 ko:K07683 ko02020,map02020 M00483 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 CCPPCCOK_01367 334390.LAF_1071 7.45e-150 422.0 COG2197@1|root,COG2197@2|Bacteria,1TSBV@1239|Firmicutes,4HC74@91061|Bacilli,3FC2M@33958|Lactobacillaceae 91061|Bacilli K PFAM regulatory protein LuxR nreC - - ko:K07696 ko02020,map02020 M00483 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg CCPPCCOK_01368 334390.LAF_1072 1.99e-53 167.0 29P7W@1|root,30A5Y@2|Bacteria,1U68N@1239|Firmicutes,4IFZK@91061|Bacilli,3F7B7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01369 334390.LAF_1073 3.43e-235 647.0 29NKS@1|root,309IR@2|Bacteria,1U568@1239|Firmicutes,4IEXI@91061|Bacilli,3F4WN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01370 334390.LAF_1074 3.49e-217 599.0 COG0142@1|root,COG0142@2|Bacteria,1UFPZ@1239|Firmicutes,4IEVZ@91061|Bacilli,3F4NS@33958|Lactobacillaceae 91061|Bacilli H geranyltranstransferase activity - - - - - - - - - - - - - CCPPCCOK_01372 334390.LAF_1076 5.89e-171 477.0 COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,3F3R2@33958|Lactobacillaceae 91061|Bacilli H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran CCPPCCOK_01373 334390.LAF_1077 5.52e-209 578.0 COG1396@1|root,COG1396@2|Bacteria,1VDMN@1239|Firmicutes,4HDVP@91061|Bacilli,3F5A3@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix - - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,TPR_12 CCPPCCOK_01374 334390.LAF_1078 2.36e-77 230.0 COG2151@1|root,COG2151@2|Bacteria,1VCAX@1239|Firmicutes,4HNBK@91061|Bacilli,3FCDE@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein - - - - - - - - - - - - FeS_assembly_P CCPPCCOK_01375 334390.LAF_1079 2.31e-278 762.0 COG2223@1|root,COG2223@2|Bacteria,1TRS9@1239|Firmicutes,4HEBM@91061|Bacilli,3FCBS@33958|Lactobacillaceae 91061|Bacilli P Major Facilitator Superfamily narK - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 CCPPCCOK_01376 334390.LAF_1080 1.67e-249 683.0 COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,3F5T2@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM CCPPCCOK_01377 334390.LAF_1081 2.34e-47 152.0 COG1977@1|root,COG1977@2|Bacteria,1U6CT@1239|Firmicutes,4IG4I@91061|Bacilli,3F7ME@33958|Lactobacillaceae 91061|Bacilli H ThiS family moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS CCPPCCOK_01378 334390.LAF_1082 7.91e-95 276.0 COG0314@1|root,COG0314@2|Bacteria,1V3V0@1239|Firmicutes,4HGZD@91061|Bacilli,3F6Q7@33958|Lactobacillaceae 91061|Bacilli H MoaE protein moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE,ThiS CCPPCCOK_01379 334390.LAF_1083 2.02e-76 228.0 2BTTC@1|root,32P0X@2|Bacteria,1U6NW@1239|Firmicutes,4IGFU@91061|Bacilli,3F87X@33958|Lactobacillaceae 91061|Bacilli S Flavodoxin - - - - - - - - - - - - Flavodoxin_1 CCPPCCOK_01380 334390.LAF_1084 1.78e-219 607.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAUK@91061|Bacilli,3F4NR@33958|Lactobacillaceae 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fecD - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD CCPPCCOK_01381 334390.LAF_1085 1.5e-182 508.0 COG1120@1|root,COG1120@2|Bacteria,1UYT8@1239|Firmicutes,4HE1M@91061|Bacilli,3FC3C@33958|Lactobacillaceae 91061|Bacilli HP AAA domain, putative AbiEii toxin, Type IV TA system fecE - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran CCPPCCOK_01382 334390.LAF_1086 6.04e-290 792.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,3F4N1@33958|Lactobacillaceae 91061|Bacilli C NADH dehydrogenase yumB GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU32100 Pyr_redox_2 CCPPCCOK_01383 334390.LAF_1087 3.62e-72 216.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - DUF1858,FeS_assembly_P CCPPCCOK_01384 1423815.BACR01000043_gene2099 1.04e-26 99.8 COG2461@1|root,COG2461@2|Bacteria,1VIMF@1239|Firmicutes,4HQ0V@91061|Bacilli,3F8S3@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1858) - - - - - - - - - - - - DUF1858 CCPPCCOK_01385 334390.LAF_1088 0.0 892.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli,3F45M@33958|Lactobacillaceae 91061|Bacilli S PAS domain XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 CCPPCCOK_01386 334390.LAF_1089 6.79e-183 512.0 COG0697@1|root,COG0697@2|Bacteria,1V86F@1239|Firmicutes,4HJWZ@91061|Bacilli,3F4CV@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA CCPPCCOK_01387 334390.LAF_0254 4.19e-150 423.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4IF4W@91061|Bacilli,3F5MX@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate - - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A CCPPCCOK_01388 334390.LAF_0253 2.84e-143 404.0 COG0110@1|root,COG0110@2|Bacteria,1V06U@1239|Firmicutes,4IPZB@91061|Bacilli,3FBEW@33958|Lactobacillaceae 91061|Bacilli S transferase hexapeptide repeat - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac CCPPCCOK_01389 334390.LAF_0252 0.0 914.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F49B@33958|Lactobacillaceae 91061|Bacilli E Peptidase C1-like family pepC - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 CCPPCCOK_01390 334390.LAF_0251 3.23e-215 593.0 COG0657@1|root,COG0657@2|Bacteria,1VSAN@1239|Firmicutes,4HEXJ@91061|Bacilli,3F60S@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Peptidase_S9 CCPPCCOK_01391 334390.LAF_0250 9.09e-164 457.0 COG0588@1|root,COG0588@2|Bacteria,1V2UT@1239|Firmicutes,4HGRK@91061|Bacilli,3FB95@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 CCPPCCOK_01392 334390.LAF_0249 1.25e-212 589.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HDX5@91061|Bacilli,3F3S0@33958|Lactobacillaceae 91061|Bacilli S Sodium Bile acid symporter family - - - ko:K07088 - - - - ko00000 - - - Mem_trans CCPPCCOK_01393 334390.LAF_0248 7.85e-242 663.0 COG3250@1|root,COG3250@2|Bacteria,1TRVA@1239|Firmicutes,4HFMH@91061|Bacilli,3F51Z@33958|Lactobacillaceae 91061|Bacilli G beta-galactosidase lacM - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N CCPPCCOK_01394 334390.LAF_0247 0.0 1320.0 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HANW@91061|Bacilli,3F4EI@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 2 family lacL - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N CCPPCCOK_01396 334390.LAF_0246 2e-108 311.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,3F703@33958|Lactobacillaceae 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT CCPPCCOK_01397 334390.LAF_0245 0.0 1403.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,3F415@33958|Lactobacillaceae 91061|Bacilli K Tex-like protein N-terminal domain protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF CCPPCCOK_01398 334390.LAF_0244 4.68e-196 543.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,3F43Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase CCPPCCOK_01399 334390.LAF_0243 0.0 975.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase CCPPCCOK_01400 334390.LAF_0242 8.7e-166 463.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,3F4D0@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein yvoA_2 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA CCPPCCOK_01402 334390.LAF_0241 1.56e-170 476.0 COG1794@1|root,COG1794@2|Bacteria,1V28U@1239|Firmicutes,4IQX8@91061|Bacilli,3FBJU@33958|Lactobacillaceae 91061|Bacilli M Belongs to the aspartate glutamate racemases family racX - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race CCPPCCOK_01403 334390.LAF_0240 1.39e-150 423.0 29NYS@1|root,309WV@2|Bacteria,1U5V7@1239|Firmicutes,4IFIU@91061|Bacilli,3F6J8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01406 334390.LAF_0239 1.94e-211 583.0 COG1409@1|root,COG1409@2|Bacteria,1VHY9@1239|Firmicutes,4HPAR@91061|Bacilli,3F3SW@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos CCPPCCOK_01407 334390.LAF_0238 0.0 930.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,3F4WU@33958|Lactobacillaceae 91061|Bacilli U amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 CCPPCCOK_01408 334390.LAF_0237 2.69e-242 698.0 COG1196@1|root,COG1196@2|Bacteria,1W39C@1239|Firmicutes,4I0DV@91061|Bacilli,3F754@33958|Lactobacillaceae 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - Gram_pos_anchor CCPPCCOK_01409 1203076.CAKF01000024_gene920 7.87e-37 134.0 2DR8S@1|root,33AQ2@2|Bacteria,1W05T@1239|Firmicutes,4HZ0I@91061|Bacilli,3F63G@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4767) - - - - - - - - - - - - DUF4767,zinc_ribbon_2 CCPPCCOK_01410 1179226.AJXO01000050_gene2710 3.13e-56 178.0 COG1942@1|root,COG1942@2|Bacteria,1V3SS@1239|Firmicutes,4HI9G@91061|Bacilli,4GZ8Y@90964|Staphylococcaceae 91061|Bacilli S Tautomerase enzyme yodA - - - - - - - - - - - Tautomerase_2 CCPPCCOK_01411 1267003.KB911410_gene915 5.37e-29 115.0 COG0664@1|root,COG0664@2|Bacteria,1TVBM@1239|Firmicutes,4HEJG@91061|Bacilli,3F4PI@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, cAMP Regulatory protein crp2 - - ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding CCPPCCOK_01412 334390.LAF_0142 1.84e-155 436.0 COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,4HN5N@91061|Bacilli,3F6YM@33958|Lactobacillaceae 91061|Bacilli C nitroreductase pnb - - - - - - - - - - - Nitroreductase CCPPCCOK_01413 525365.HMPREF0548_0513 9.46e-106 312.0 COG0596@1|root,COG0596@2|Bacteria,1USYC@1239|Firmicutes,4HBXD@91061|Bacilli,3F5NJ@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family - - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 CCPPCCOK_01414 575594.ACOH01000002_gene1011 1.69e-99 300.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,3F3VA@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short CCPPCCOK_01415 764298.STRMA_0452 1.47e-30 115.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli 91061|Bacilli C reductase - - - - - - - - - - - - Aldo_ket_red CCPPCCOK_01416 257314.LJ_1158 1.68e-57 188.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3F3PW@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase - - - - - - - - - - - - Aldo_ket_red CCPPCCOK_01419 658655.HMPREF0988_01267 7.43e-08 52.8 COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,25B10@186801|Clostridia,27JTT@186928|unclassified Lachnospiraceae 186801|Clostridia C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red CCPPCCOK_01420 334390.LAF_0159 1.14e-231 637.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,3F4Z6@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C CCPPCCOK_01421 1423734.JCM14202_2246 2.59e-45 158.0 COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,4HBDW@91061|Bacilli,3FB94@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class-V pucG GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 CCPPCCOK_01422 1423734.JCM14202_2246 2.07e-129 380.0 COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,4HBDW@91061|Bacilli,3FB94@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class-V pucG GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 CCPPCCOK_01423 1267003.KB911381_gene2208 1.91e-76 245.0 COG2508@1|root,COG2508@2|Bacteria,1TRDF@1239|Firmicutes,4H9KC@91061|Bacilli,3F5A2@33958|Lactobacillaceae 91061|Bacilli QT Purine catabolism regulatory protein-like family - - - ko:K09684 - - - - ko00000,ko03000 - - - HTH_30,PucR CCPPCCOK_01424 525318.HMPREF0497_0519 3.94e-168 480.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,3F3S3@33958|Lactobacillaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily - - 3.5.2.3,3.5.2.5 ko:K01465,ko:K01466 ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120 M00051,M00546 R01993,R02425 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 CCPPCCOK_01425 334390.LAF_0160 5.02e-124 367.0 COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,4HAE4@91061|Bacilli,3F5V9@33958|Lactobacillaceae 91061|Bacilli E Peptidase family M20/M25/M40 allC - 3.5.3.9 ko:K02083 ko00230,ko01120,map00230,map01120 - R02423 RC00064 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 CCPPCCOK_01426 334390.LAF_0163 3.99e-257 704.0 COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,4HB6X@91061|Bacilli,3F4JZ@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH2 MDH2 oxidoreductase family allD - 1.1.1.350 ko:K00073 ko00230,ko01120,map00230,map01120 - R02935,R02936 RC00169 ko00000,ko00001,ko01000 - - - Ldh_2 CCPPCCOK_01427 1423743.JCM14108_1794 1.09e-13 70.9 COG0074@1|root,COG0074@2|Bacteria,1UHQ6@1239|Firmicutes,4H9VN@91061|Bacilli,3F5F7@33958|Lactobacillaceae 91061|Bacilli C CoA-ligase fdrA - - ko:K02381 - - - - ko00000 - - - CoA_binding,DUF1116,Ligase_CoA CCPPCCOK_01428 334390.LAF_0165 7.41e-227 624.0 COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,4HEK7@91061|Bacilli,3FB76@33958|Lactobacillaceae 91061|Bacilli F Inosine-uridine preferring nucleoside hydrolase rihA - - ko:K01250 - - - - ko00000,ko01000 - - - IU_nuc_hydro CCPPCCOK_01429 334390.LAF_0166 2.24e-159 446.0 COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,4HN5N@91061|Bacilli,3F6YM@33958|Lactobacillaceae 91061|Bacilli C nitroreductase - - - - - - - - - - - - Nitroreductase CCPPCCOK_01430 334390.LAF_0167 1.98e-176 491.0 COG2755@1|root,COG2755@2|Bacteria,1V4VT@1239|Firmicutes,4HXCK@91061|Bacilli,3F4P8@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 CCPPCCOK_01431 334390.LAF_0168 1.06e-70 213.0 COG1694@1|root,COG1694@2|Bacteria,1VFER@1239|Firmicutes,4HM4N@91061|Bacilli,3F7BQ@33958|Lactobacillaceae 91061|Bacilli S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG,PRA-PH CCPPCCOK_01432 334390.LAF_0169 2.2e-252 692.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F42F@33958|Lactobacillaceae 91061|Bacilli E alcohol dehydrogenase adh1 - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CCPPCCOK_01433 334390.LAF_0170 0.0 1667.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli,3F3UH@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 CCPPCCOK_01434 334390.LAF_0172 6.83e-115 335.0 COG0583@1|root,COG0583@2|Bacteria,1UZXK@1239|Firmicutes,4HUWT@91061|Bacilli,3F41Q@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate CCPPCCOK_01436 334390.LAF_0174 2.05e-179 499.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,3F4IY@33958|Lactobacillaceae 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase CCPPCCOK_01438 1033837.WANG_1728 4.74e-23 88.2 2A7T7@1|root,30WS9@2|Bacteria,1U6PA@1239|Firmicutes,4IGGA@91061|Bacilli,3F892@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01439 334390.LAF_0849 1.19e-41 137.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc CCPPCCOK_01440 334390.LAF_0848 3.37e-96 283.0 COG1302@1|root,COG1302@2|Bacteria,1V8FM@1239|Firmicutes,4HJ0H@91061|Bacilli,3F77J@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function asp1 - - - - - - - - - - - Asp23 CCPPCCOK_01441 1138822.PL11_10380 2.24e-113 327.0 2ED8H@1|root,33752@2|Bacteria,1VK2R@1239|Firmicutes,4HQ99@91061|Bacilli,3F8BK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01442 334390.LAF_1029 6.33e-72 216.0 COG0239@1|root,COG0239@2|Bacteria,1VM30@1239|Firmicutes,4HRC4@91061|Bacilli,3F8A8@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB CCPPCCOK_01443 334390.LAF_1030 1.42e-71 216.0 COG0239@1|root,COG0239@2|Bacteria 2|Bacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB CCPPCCOK_01444 334390.LAF_1031 2.51e-90 265.0 COG0346@1|root,COG0346@2|Bacteria,1V7D7@1239|Firmicutes,4HIGP@91061|Bacilli,3F6XZ@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase CCPPCCOK_01445 334390.LAF_1032 6.33e-133 376.0 COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,4HMP7@91061|Bacilli,3F6WQ@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 CCPPCCOK_01446 334390.LAF_1033 0.0 1091.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,3F51C@33958|Lactobacillaceae 91061|Bacilli S ABC1 family ubiB - - ko:K03688 - - - - ko00000 - - - ABC1,APH CCPPCCOK_01447 334390.LAF_1034 5.02e-165 462.0 COG1018@1|root,COG1018@2|Bacteria,1VF2T@1239|Firmicutes,4I4BK@91061|Bacilli,3F9TF@33958|Lactobacillaceae 91061|Bacilli C Oxidoreductase NAD-binding domain - - - - - - - - - - - - NAD_binding_1 CCPPCCOK_01448 334390.LAF_1035 4.24e-218 602.0 COG1940@1|root,COG1940@2|Bacteria,1V3T9@1239|Firmicutes,4HU07@91061|Bacilli,3FC7F@33958|Lactobacillaceae 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK CCPPCCOK_01449 334390.LAF_1036 7.62e-53 166.0 29PBP@1|root,30A9X@2|Bacteria,1U6DN@1239|Firmicutes,4IG5D@91061|Bacilli,3F7NV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01450 334390.LAF_1037 1.03e-106 307.0 COG3682@1|root,COG3682@2|Bacteria,1VA7Q@1239|Firmicutes,4HKGF@91061|Bacilli,3F7D0@33958|Lactobacillaceae 91061|Bacilli K Copper transport repressor CopY TcrY atkY - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R CCPPCCOK_01452 334390.LAF_1038 4.19e-263 721.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family int2 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase CCPPCCOK_01453 1069534.LRC_10300 2.06e-51 173.0 COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,4HEKB@91061|Bacilli,3F481@33958|Lactobacillaceae 91061|Bacilli L Probable transposase - - - - - - - - - - - - OrfB_IS605,OrfB_Zn_ribbon CCPPCCOK_01454 1423747.BAMJ01000054_gene2155 1.02e-32 127.0 COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,4HDHP@91061|Bacilli,3F57A@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - ko:K08166 - - - - ko00000,ko02000 2.A.1.3.10 - - MFS_1 CCPPCCOK_01455 1267003.KB911394_gene124 5.19e-55 185.0 COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,4HDHP@91061|Bacilli,3F57A@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - ko:K08166 - - - - ko00000,ko02000 2.A.1.3.10 - - MFS_1 CCPPCCOK_01456 1423724.BAMM01000001_gene94 1.53e-87 266.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F42F@33958|Lactobacillaceae 91061|Bacilli E alcohol dehydrogenase adh2 - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CCPPCCOK_01457 220668.lp_2873 2.07e-71 224.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F42F@33958|Lactobacillaceae 91061|Bacilli E alcohol dehydrogenase adh2 - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CCPPCCOK_01458 862514.HMPREF0623_0561 1.78e-19 84.0 COG0716@1|root,COG0716@2|Bacteria,1V465@1239|Firmicutes,4HN5X@91061|Bacilli,3F7H7@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 CCPPCCOK_01459 334390.LAF_0954 2.39e-28 110.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HCVT@91061|Bacilli,3F4ZZ@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 CCPPCCOK_01460 393480.FNP_1613 5.08e-14 72.0 COG0655@1|root,COG0655@2|Bacteria 2|Bacteria S NAD(P)H dehydrogenase (quinone) activity - - - - - - - - - - - - FMN_red CCPPCCOK_01461 1423815.BACR01000048_gene2312 6.36e-66 204.0 29NII@1|root,309GE@2|Bacteria,1U50X@1239|Firmicutes,4IGPK@91061|Bacilli,3F8K2@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4411) - - - - - - - - - - - - DUF4411 CCPPCCOK_01462 1423815.BACR01000048_gene2313 2.22e-261 719.0 COG2856@1|root,COG2856@2|Bacteria,1TQAC@1239|Firmicutes,4HJ3C@91061|Bacilli,3F5G6@33958|Lactobacillaceae 91061|Bacilli E IrrE N-terminal-like domain - - - - - - - - - - - - Peptidase_M78 CCPPCCOK_01463 1074451.CRL705_1859 0.0 1523.0 COG0178@1|root,COG0178@2|Bacteria,1TR1H@1239|Firmicutes,4H9RE@91061|Bacilli,3F50Y@33958|Lactobacillaceae 91061|Bacilli L ABC transporter uvrA2 - - - - - - - - - - - ABC_tran CCPPCCOK_01464 220668.lp_3469 4.32e-17 79.3 COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4HARI@91061|Bacilli,3F3PC@33958|Lactobacillaceae 91061|Bacilli G -beta-galactosidase lacA - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M CCPPCCOK_01465 334390.LAF_0074 1.27e-271 745.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HBRZ@91061|Bacilli,3FB6J@33958|Lactobacillaceae 91061|Bacilli F Nucleoside transporter nupG - - ko:K03317,ko:K11535,ko:K16323 - - - - ko00000,ko02000 2.A.41,2.A.41.1 - - Nucleos_tra2_C,Nucleos_tra2_N CCPPCCOK_01466 349123.Lreu23DRAFT_4953 2.31e-185 519.0 COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,4HB17@91061|Bacilli,3F4T0@33958|Lactobacillaceae 91061|Bacilli F Nucleoside rihA - 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro CCPPCCOK_01467 334390.LAF_0075 6.1e-172 480.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,3F3ZX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB CCPPCCOK_01468 334390.LAF_0076 3.3e-209 580.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,3F4RU@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc CCPPCCOK_01469 334390.LAF_0077 8.77e-188 523.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,3F47R@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc CCPPCCOK_01470 334390.LAF_0078 1.47e-41 136.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,3F823@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF951) yyzM - - - - - - - - - - - DUF951 CCPPCCOK_01471 334390.LAF_0079 6.1e-255 700.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,3F3TK@33958|Lactobacillaceae 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C CCPPCCOK_01472 334390.LAF_0080 9.67e-175 488.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HJMB@91061|Bacilli,3FCFF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1129) - - - - - - - - - - - - DUF1129 CCPPCCOK_01473 334390.LAF_0081 8.13e-263 721.0 COG0516@1|root,COG0516@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,3F3XN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH CCPPCCOK_01474 334390.LAF_0084 1.21e-222 615.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr CCPPCCOK_01475 334390.LAF_0085 6.76e-170 476.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,3F4M5@33958|Lactobacillaceae 91061|Bacilli M biosynthesis protein epsB - - - - - - - - - - - GNVR,Wzz CCPPCCOK_01476 334390.LAF_0086 4.34e-157 442.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,3F4BM@33958|Lactobacillaceae 91061|Bacilli D Capsular exopolysaccharide family ywqD - - - - - - - - - - - AAA_31,ParA CCPPCCOK_01477 334390.LAF_0087 4.63e-177 494.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,3F3RT@33958|Lactobacillaceae 91061|Bacilli GM PHP domain protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - CCPPCCOK_01478 334390.LAF_0088 1.52e-116 336.0 COG2148@1|root,COG2148@2|Bacteria,1TQX9@1239|Firmicutes,4HAF1@91061|Bacilli,3F9V4@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase capM - - ko:K13012 - - - - ko00000,ko01005 - - - Bac_transf CCPPCCOK_01479 665571.STHERM_c15680 1.01e-82 263.0 COG0438@1|root,COG0438@2|Bacteria,2J8DI@203691|Spirochaetes 203691|Spirochaetes M Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 CCPPCCOK_01480 1045854.WKK_02460 1.08e-131 385.0 COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,4HGEP@91061|Bacilli,4AXS1@81850|Leuconostocaceae 91061|Bacilli M Stealth protein CR2, conserved region 2 wefC - - - - - - - - - - - Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4 CCPPCCOK_01482 1214166.ALLG01000021_gene19 3.2e-31 126.0 COG1216@1|root,COG1216@2|Bacteria,1UJ7P@1239|Firmicutes,4IT3V@91061|Bacilli,1WSJC@1307|Streptococcus suis 91061|Bacilli S Glycosyl transferase family 2 XK27_09035 - - ko:K12997 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 CCPPCCOK_01483 1045004.OKIT_0062 7.25e-48 174.0 COG0438@1|root,COG0438@2|Bacteria,1U3MV@1239|Firmicutes,4IDEK@91061|Bacilli,4AYN9@81850|Leuconostocaceae 91061|Bacilli M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - CCPPCCOK_01484 1045854.WKK_02450 6.8e-95 304.0 COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,4HCW6@91061|Bacilli,4AXR3@81850|Leuconostocaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score cps2I - - - - - - - - - - - Polysacc_synt CCPPCCOK_01485 334390.LAF_0096 6.44e-205 567.0 COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,3F4F8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CCPPCCOK_01486 334390.LAF_0097 2.77e-140 395.0 COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4HFQB@91061|Bacilli,3F4FN@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom CCPPCCOK_01487 334390.LAF_0098 1.39e-258 707.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,3F3R6@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd CCPPCCOK_01488 334390.LAF_0099 3.72e-202 560.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,3F4QS@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind CCPPCCOK_01489 1410628.JNKS01000006_gene1595 9.46e-38 145.0 COG0463@1|root,COG0463@2|Bacteria,1VCNF@1239|Firmicutes,252FN@186801|Clostridia,27NM2@186928|unclassified Lachnospiraceae 186801|Clostridia M Glycosyltransferase family 92 - - - - - - - - - - - - Glyco_transf_92 CCPPCCOK_01491 334390.LAF_0106 2.75e-121 345.0 COG3542@1|root,COG3542@2|Bacteria,1V52Y@1239|Firmicutes,4HH9T@91061|Bacilli,3F77H@33958|Lactobacillaceae 91061|Bacilli S Cupin superfamily (DUF985) - - - ko:K09705 - - - - ko00000 - - - Cupin_5 CCPPCCOK_01492 334390.LAF_0107 2.49e-157 442.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,3F3Y0@33958|Lactobacillaceae 91061|Bacilli K response regulator vanR - - - - - - - - - - - Response_reg,Trans_reg_C CCPPCCOK_01493 334390.LAF_0108 2.96e-265 727.0 COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,4HARU@91061|Bacilli,3F479@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase hpk31 - - - - - - - - - - - HATPase_c,HisKA CCPPCCOK_01494 334390.LAF_0109 7.62e-266 732.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,3F43S@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 CCPPCCOK_01495 334390.LAF_0110 6.18e-180 504.0 COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,4HN4R@91061|Bacilli,3FB4H@33958|Lactobacillaceae 91061|Bacilli E AzlC protein - - - - - - - - - - - - AzlC CCPPCCOK_01496 334390.LAF_0111 6.38e-78 233.0 COG4392@1|root,COG4392@2|Bacteria,1UF1S@1239|Firmicutes,4HQ7J@91061|Bacilli,3F7GD@33958|Lactobacillaceae 91061|Bacilli S branched-chain amino acid - - - - - - - - - - - - AzlD CCPPCCOK_01497 1138822.PL11_10620 1.03e-105 305.0 COG1943@1|root,COG1943@2|Bacteria,1VAIQ@1239|Firmicutes,4HI29@91061|Bacilli,3F68H@33958|Lactobacillaceae 91061|Bacilli L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp CCPPCCOK_01498 334390.LAF_1787 1.94e-74 224.0 COG1562@1|root,COG1562@2|Bacteria,1TQHF@1239|Firmicutes,4HA1A@91061|Bacilli,3F8JK@33958|Lactobacillaceae 91061|Bacilli I Squalene/phytoene synthase crtM - 2.5.1.32,2.5.1.96,2.5.1.99 ko:K02291,ko:K10208 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R00702,R02065,R04218,R07270,R07652,R09793,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY CCPPCCOK_01500 334390.LAF_1747 0.0 1662.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N CCPPCCOK_01501 334390.LAF_1748 4.33e-191 530.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3FC87@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 CCPPCCOK_01502 334390.LAF_1749 3.81e-169 473.0 COG2188@1|root,COG2188@2|Bacteria,1TTCD@1239|Firmicutes,4HEXQ@91061|Bacilli,3F4DA@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein gntR - - - - - - - - - - - GntR,UTRA CCPPCCOK_01503 334390.LAF_1750 4.23e-115 330.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHFK@91061|Bacilli,3FC62@33958|Lactobacillaceae 91061|Bacilli J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ebsC - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit CCPPCCOK_01504 334390.LAF_1751 3.78e-167 468.0 arCOG05209@1|root,31PIN@2|Bacteria,1V5G2@1239|Firmicutes,4HIRV@91061|Bacilli,3F6X9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01505 334390.LAF_1752 0.0 932.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD2 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 CCPPCCOK_01506 334390.LAF_1753 4.35e-198 548.0 COG1082@1|root,COG1082@2|Bacteria,1VSC9@1239|Firmicutes,4HUQI@91061|Bacilli,3F4RS@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 CCPPCCOK_01507 334390.LAF_1754 9.84e-112 322.0 COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,4HJXK@91061|Bacilli,3FBF9@33958|Lactobacillaceae 91061|Bacilli K Domain of unknown function (DUF1836) - - - - - - - - - - - - DUF1836 CCPPCCOK_01508 334390.LAF_1755 3.4e-116 335.0 COG0702@1|root,COG0702@2|Bacteria,1U673@1239|Firmicutes,4IFXN@91061|Bacilli,3F78A@33958|Lactobacillaceae 91061|Bacilli GM epimerase - - - - - - - - - - - - NAD_binding_10 CCPPCCOK_01509 334390.LAF_1756 0.0 876.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3TX@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 CCPPCCOK_01510 334390.LAF_1757 3.57e-108 311.0 COG1780@1|root,COG1780@2|Bacteria,1VWJA@1239|Firmicutes,4HW5I@91061|Bacilli,3FBB8@33958|Lactobacillaceae 91061|Bacilli F Belongs to the NrdI family nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI CCPPCCOK_01511 334390.LAF_1758 5.2e-98 285.0 COG2764@1|root,COG2764@2|Bacteria,1V6QS@1239|Firmicutes,4HK80@91061|Bacilli,3F6RM@33958|Lactobacillaceae 91061|Bacilli S 3-demethylubiquinone-9 3-methyltransferase - - - ko:K04750 - - - - ko00000 - - - 3-dmu-9_3-mt CCPPCCOK_01512 334390.LAF_1759 2.96e-265 728.0 COG2807@1|root,COG2807@2|Bacteria,1TP9R@1239|Firmicutes,4H9YZ@91061|Bacilli,3F52B@33958|Lactobacillaceae 91061|Bacilli P Transporter, major facilitator family protein yycB - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 CCPPCCOK_01514 334390.LAF_0067 4.91e-240 660.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,3F3V6@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b CCPPCCOK_01516 334390.LAF_0069 1.55e-285 785.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli,3F4HA@33958|Lactobacillaceae 91061|Bacilli P ABC transporter glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 CCPPCCOK_01517 334390.LAF_0070 2.59e-174 486.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran CCPPCCOK_01518 334390.LAF_0071 0.0 869.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease aapA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease CCPPCCOK_01520 1423790.BN53_00380 8.12e-106 306.0 2AYWY@1|root,3354X@2|Bacteria,1VUSY@1239|Firmicutes,4HVEY@91061|Bacilli,3FC0S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01521 31954.BPSP_1152 0.0 1158.0 COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZRE@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase - - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase CCPPCCOK_01522 334390.LAF_1466 1.04e-45 147.0 COG2608@1|root,COG2608@2|Bacteria,1VFJ8@1239|Firmicutes,4HNY2@91061|Bacilli,3F830@33958|Lactobacillaceae 91061|Bacilli P Heavy-metal-associated domain copZ - - - - - - - - - - - HMA CCPPCCOK_01523 334390.LAF_1465 4.86e-61 187.0 COG2846@1|root,COG2846@2|Bacteria,1VI78@1239|Firmicutes,4HPAS@91061|Bacilli,3F71U@33958|Lactobacillaceae 91061|Bacilli D Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - - - - - - - - - - - CCPPCCOK_01524 334390.LAF_1464 1.28e-145 411.0 COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,4HDG1@91061|Bacilli,3F4YM@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, Crp Fnr family - - - ko:K21562 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding CCPPCCOK_01525 334390.LAF_0410 0.0 1082.0 COG0492@1|root,COG3634@1|root,COG0492@2|Bacteria,COG3634@2|Bacteria,1TNZS@1239|Firmicutes,4HD19@91061|Bacilli,3F5GD@33958|Lactobacillaceae 91061|Bacilli C Thioredoxin domain - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Thioredoxin_3 CCPPCCOK_01526 334390.LAF_0409 1.88e-135 383.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli,3F50G@33958|Lactobacillaceae 91061|Bacilli O Peroxiredoxin ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA CCPPCCOK_01527 334390.LAF_0406 2.07e-281 771.0 COG2211@1|root,COG2211@2|Bacteria,1V3NJ@1239|Firmicutes,4HTUC@91061|Bacilli,3F4KD@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator - - - - - - - - - - - - MFS_1 CCPPCCOK_01528 334390.LAF_0405 0.0 1153.0 COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HA16@91061|Bacilli,3F4SQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.37 ko:K01198 ko00520,ko01100,map00520,map01100 - R01433 RC00467 ko00000,ko00001,ko01000 - GH43 - Glyco_hydro_43 CCPPCCOK_01529 1203076.CAKF01000022_gene625 7.37e-106 315.0 COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V48H@1239|Firmicutes,4HKPP@91061|Bacilli,3F59N@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - Cupin_2,HTH_18 CCPPCCOK_01530 334390.LAF_0403 0.0 1019.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4HBRJ@91061|Bacilli,3FCAE@33958|Lactobacillaceae 91061|Bacilli G Xylulose kinase xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU17610 FGGY_C,FGGY_N CCPPCCOK_01531 334390.LAF_0402 0.0 931.0 COG2115@1|root,COG2115@2|Bacteria,1TQW2@1239|Firmicutes,4H9WG@91061|Bacilli,3F5ME@33958|Lactobacillaceae 91061|Bacilli G Belongs to the xylose isomerase family xylA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - AP_endonuc_2 CCPPCCOK_01532 334390.LAF_0401 0.0 878.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,3F3ZS@33958|Lactobacillaceae 91061|Bacilli EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family xylT - - - - - - - - - - - Sugar_tr CCPPCCOK_01533 334390.LAF_0400 9.01e-276 754.0 COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,4HDE3@91061|Bacilli,3F540@33958|Lactobacillaceae 91061|Bacilli GK ROK family xylR - - - - - - - - - - - HTH_24,MarR,ROK CCPPCCOK_01534 334390.LAF_0399 1.24e-196 546.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport - - - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport CCPPCCOK_01535 334390.LAF_0398 0.0 900.0 COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS6U@91061|Bacilli,3FBSR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA CCPPCCOK_01536 334390.LAF_0397 8.03e-170 474.0 COG0745@1|root,COG0745@2|Bacteria,1TQUQ@1239|Firmicutes,4HAXP@91061|Bacilli,3F3QZ@33958|Lactobacillaceae 91061|Bacilli K response regulator yclJ - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C CCPPCCOK_01540 334390.LAF_0556 1.12e-90 265.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F6HJ@33958|Lactobacillaceae 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC CCPPCCOK_01541 334390.LAF_0557 8.44e-150 423.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli,3F5G4@33958|Lactobacillaceae 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA CCPPCCOK_01542 334390.LAF_0558 1.69e-262 717.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,3F4BZ@33958|Lactobacillaceae 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA CCPPCCOK_01543 334390.LAF_0559 1.46e-147 415.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,3F6QR@33958|Lactobacillaceae 91061|Bacilli Q Thioredoxin yjbH - - - - - - - - - - - Thioredoxin_5 CCPPCCOK_01544 334390.LAF_0560 1.5e-158 444.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,3F452@33958|Lactobacillaceae 91061|Bacilli S RelA SpoT domain protein yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT CCPPCCOK_01545 334390.LAF_0561 9.49e-197 545.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,3F45D@33958|Lactobacillaceae 91061|Bacilli F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase CCPPCCOK_01546 334390.LAF_0562 8.94e-220 605.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F4AU@33958|Lactobacillaceae 91061|Bacilli G Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 CCPPCCOK_01547 334390.LAF_0563 1.09e-250 687.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,3F3RC@33958|Lactobacillaceae 91061|Bacilli G Lactonase, 7-bladed beta-propeller pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase CCPPCCOK_01548 334390.LAF_0564 1.12e-207 573.0 COG0500@1|root,COG2226@2|Bacteria,1V1WE@1239|Firmicutes,4HGQ9@91061|Bacilli,3F4U3@33958|Lactobacillaceae 91061|Bacilli H Methyltransferase rrmA - 2.1.1.187 ko:K00563,ko:K10947 - - R07233 RC00003 ko00000,ko01000,ko03000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 CCPPCCOK_01549 334390.LAF_0565 2.01e-123 351.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,3F42Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase CCPPCCOK_01550 334390.LAF_0566 0.0 1411.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,3F3JZ@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma CCPPCCOK_01551 1423814.HMPREF0549_0182 4.5e-12 60.1 29PVH@1|root,30ATR@2|Bacteria,1U73D@1239|Firmicutes,4IGXZ@91061|Bacilli,3F8XG@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF4044) - - - - - - - - - - - - DUF4044 CCPPCCOK_01552 334390.LAF_0567 6.91e-76 227.0 29PGG@1|root,30AEM@2|Bacteria,1U6JI@1239|Firmicutes,4IGC0@91061|Bacilli,3F81C@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF3397 CCPPCCOK_01553 334390.LAF_0568 7.65e-104 299.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,3F6K3@33958|Lactobacillaceae 91061|Bacilli K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ CCPPCCOK_01554 334390.LAF_0569 1.54e-220 608.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,3F3MF@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 CCPPCCOK_01555 334390.LAF_0570 3.03e-30 112.0 COG4839@1|root,COG4839@2|Bacteria,1VCE5@1239|Firmicutes,4HM4W@91061|Bacilli,3F6KG@33958|Lactobacillaceae 91061|Bacilli D Cell division protein FtsL ftsL - - - - - - - - - - - DivIC CCPPCCOK_01556 334390.LAF_0571 0.0 1380.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,3F47N@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase CCPPCCOK_01557 334390.LAF_0572 4.46e-227 625.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,3F3YP@33958|Lactobacillaceae 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 CCPPCCOK_01558 334390.LAF_0573 0.0 901.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,3F49W@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M CCPPCCOK_01559 334390.LAF_0574 1.69e-258 709.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,3F4FW@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 CCPPCCOK_01560 334390.LAF_0575 3.14e-192 534.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,3F406@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 CCPPCCOK_01561 334390.LAF_0576 4.88e-300 822.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,3F413@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA CCPPCCOK_01562 334390.LAF_0577 9.01e-294 803.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,3F4V1@33958|Lactobacillaceae 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin CCPPCCOK_01563 334390.LAF_0578 2.49e-100 291.0 COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,3F7MQ@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF CCPPCCOK_01564 334390.LAF_0579 7.27e-56 174.0 COG0762@1|root,COG0762@2|Bacteria,1VEKA@1239|Firmicutes,4HNJR@91061|Bacilli,3F843@33958|Lactobacillaceae 91061|Bacilli S YGGT family ylmG - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT CCPPCCOK_01565 334390.LAF_0580 2.49e-186 518.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,3F48W@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein ylmH - - - - - - - - - - - S4 CCPPCCOK_01566 334390.LAF_0581 6.19e-143 405.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,3F4IN@33958|Lactobacillaceae 91061|Bacilli D DivIVA domain protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA CCPPCCOK_01568 334390.LAF_0582 0.0 1885.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,3F3X4@33958|Lactobacillaceae 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS CCPPCCOK_01569 334390.LAF_0583 9.99e-44 142.0 COG1278@1|root,COG1278@2|Bacteria,1W688@1239|Firmicutes,4I1Y3@91061|Bacilli,3F81I@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein cspB - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CCPPCCOK_01570 334390.LAF_0584 5.21e-126 358.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,3F53J@33958|Lactobacillaceae 91061|Bacilli L ADP-ribose pyrophosphatase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX CCPPCCOK_01572 334390.LAF_0586 3.26e-162 454.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,3F4HE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 CCPPCCOK_01573 334390.LAF_0587 7.86e-77 229.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli,3F7E3@33958|Lactobacillaceae 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 CCPPCCOK_01574 334390.LAF_0588 1.98e-282 770.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,3F4N5@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans CCPPCCOK_01575 334390.LAF_0066 3.66e-315 858.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,3F3M6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b CCPPCCOK_01576 334390.LAF_0065 0.0 1736.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,3F3TE@33958|Lactobacillaceae 91061|Bacilli L Putative exonuclease SbcCD, C subunit sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C CCPPCCOK_01577 334390.LAF_0064 3.68e-278 759.0 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli,3F4A9@33958|Lactobacillaceae 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C CCPPCCOK_01578 1136177.KCA1_1714 9.8e-09 52.0 2DKST@1|root,30APB@2|Bacteria,1U6XZ@1239|Firmicutes,4IGS5@91061|Bacilli,3F8PK@33958|Lactobacillaceae 91061|Bacilli S D-Ala-teichoic acid biosynthesis protein dltX - - - - - - - - - - - DUF3687 CCPPCCOK_01579 334390.LAF_0063 0.0 1028.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,3F49R@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C CCPPCCOK_01580 334390.LAF_0062 2.63e-305 831.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,3F4KK@33958|Lactobacillaceae 91061|Bacilli M MBOAT, membrane-bound O-acyltransferase family dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT CCPPCCOK_01581 334390.LAF_0061 3.78e-48 154.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,3F7Q1@33958|Lactobacillaceae 91061|Bacilli J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding CCPPCCOK_01582 334390.LAF_0060 1.32e-307 838.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,3F3WE@33958|Lactobacillaceae 91061|Bacilli M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD CCPPCCOK_01583 1302286.BAOT01000060_gene2014 7.63e-155 443.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,3F40K@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase iolS - - ko:K06607 - - - - ko00000,ko01000 - - - Aldo_ket_red CCPPCCOK_01584 1203076.CAKF01000021_gene1391 8.02e-250 695.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans CCPPCCOK_01585 334390.LAF_0057 4.83e-313 858.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F4GQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr CCPPCCOK_01586 334390.LAF_0056 6.62e-279 762.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 CCPPCCOK_01587 334390.LAF_0055 8.67e-141 400.0 COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,4HBEV@91061|Bacilli,3F48A@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 CCPPCCOK_01588 334390.LAF_0054 2.85e-243 669.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,3F3U5@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL CCPPCCOK_01589 334390.LAF_0053 2.71e-197 547.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 CCPPCCOK_01590 334390.LAF_0052 0.0 908.0 COG0438@1|root,COG0438@2|Bacteria,1VSNK@1239|Firmicutes,4HU8G@91061|Bacilli,3F4VP@33958|Lactobacillaceae 91061|Bacilli M Poly(Glycerol-phosphate) alpha-glucosyltransferase - - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glycos_transf_1 CCPPCCOK_01591 334390.LAF_0051 0.0 979.0 COG0438@1|root,COG0438@2|Bacteria,1V09I@1239|Firmicutes,4HDDD@91061|Bacilli,3FBDH@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 tagE6 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glyco_trans_A_1,Glyco_transf_4,Glycos_transf_1 CCPPCCOK_01592 1203076.CAKF01000023_gene659 3.97e-62 193.0 2DNYJ@1|root,32ZT4@2|Bacteria,1VFXH@1239|Firmicutes,4HPEG@91061|Bacilli,3F6B5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2628 CCPPCCOK_01593 575594.ACOH01000002_gene1015 7.45e-25 107.0 COG2610@1|root,COG2610@2|Bacteria 2|Bacteria EG gluconate transmembrane transporter activity gntT - - - - - - - - - - - DctM CCPPCCOK_01594 334390.LAF_0048 6.19e-149 419.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,3F487@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran CCPPCCOK_01595 334390.LAF_0047 5.85e-169 472.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,3F47Y@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase CCPPCCOK_01596 334390.LAF_0046 1.14e-123 352.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,3F4SR@33958|Lactobacillaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran CCPPCCOK_01597 334390.LAF_0045 0.0 891.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CCPPCCOK_01598 334390.LAF_0044 9.69e-317 862.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,3F3RQ@33958|Lactobacillaceae 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt CCPPCCOK_01599 575594.ACOH01000026_gene64 2.81e-212 588.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,3F45K@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH CCPPCCOK_01600 334390.LAF_0043 1.29e-92 273.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_N CCPPCCOK_01601 334390.LAF_0042 6.55e-166 464.0 COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli,3F3VV@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system ybhF_2 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CCPPCCOK_01602 334390.LAF_0041 5.27e-243 670.0 COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,3F40D@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 CCPPCCOK_01603 334390.LAF_0040 3.67e-86 253.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,3F72U@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin CCPPCCOK_01604 334390.LAF_0039 0.0 1024.0 COG0584@1|root,COG0584@2|Bacteria,1UG1C@1239|Firmicutes,4HCPQ@91061|Bacilli,3F3SZ@33958|Lactobacillaceae 91061|Bacilli C phosphodiesterase glpQ4 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,GDPD_2,GPDPase_memb CCPPCCOK_01605 334390.LAF_0038 3.09e-211 583.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3F3PW@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase - - - - - - - - - - - - Aldo_ket_red CCPPCCOK_01606 334390.LAF_0037 0.0 2617.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,3F3Z0@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C CCPPCCOK_01607 334390.LAF_0036 0.0 2416.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,3F3RS@33958|Lactobacillaceae 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C CCPPCCOK_01608 334390.LAF_0035 0.0 966.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N CCPPCCOK_01609 334390.LAF_0033 0.0 1330.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F43D@33958|Lactobacillaceae 91061|Bacilli O associated with various cellular activities clpE - - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR CCPPCCOK_01610 334390.LAF_0032 1.15e-47 152.0 2BZQ9@1|root,3490W@2|Bacteria,1VZ0G@1239|Firmicutes,4HY72@91061|Bacilli,3F7PN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01611 334390.LAF_0031 3.41e-278 761.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase - - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CCPPCCOK_01612 334390.LAF_0030 1.97e-231 637.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,3F4US@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhD - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C CCPPCCOK_01613 334390.LAF_0029 2.32e-234 643.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta - - - ko:K06889 - - - - ko00000 - - - DLH,FSH1,Hydrolase_4 CCPPCCOK_01614 334390.LAF_0028 2.97e-244 669.0 COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,4HC4Y@91061|Bacilli,3F4NH@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolase, choloylglycine hydrolase family protein - - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH CCPPCCOK_01615 314315.LCA_0051 4.98e-20 87.4 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,3F4J8@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ysdB - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 CCPPCCOK_01617 334390.LAF_0026 7.69e-150 422.0 COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HF3K@91061|Bacilli,3F4ST@33958|Lactobacillaceae 91061|Bacilli S beta-phosphoglucomutase pgmB - 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 CCPPCCOK_01618 334390.LAF_0025 0.0 1517.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,3F3PG@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 65, central catalytic mapA - 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m CCPPCCOK_01619 334390.LAF_0024 0.0 868.0 COG2211@1|root,COG2211@2|Bacteria,1TRP7@1239|Firmicutes,4HCUK@91061|Bacilli,3F3YZ@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator malT - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 CCPPCCOK_01620 334390.LAF_0023 6.58e-225 619.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,3F4TM@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family malR1 - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CCPPCCOK_01621 334390.LAF_0022 3.03e-94 275.0 COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,4HKZD@91061|Bacilli,3F73Q@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator ywnA - - - - - - - - - - - Rrf2 CCPPCCOK_01622 334390.LAF_0021 1.01e-105 305.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,3F3YX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase CCPPCCOK_01623 334390.LAF_0020 9.52e-270 742.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,3F45X@33958|Lactobacillaceae 91061|Bacilli O serine protease htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 CCPPCCOK_01624 334390.LAF_0019 5.49e-197 545.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,3F3S4@33958|Lactobacillaceae 91061|Bacilli S domain protein vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 CCPPCCOK_01625 334390.LAF_0018 2.05e-185 516.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,3F3PV@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycI - - - - - - - - - - - YycI CCPPCCOK_01626 334390.LAF_0017 1.8e-306 836.0 COG4863@1|root,COG4863@2|Bacteria,1V32Y@1239|Firmicutes,4HG2Q@91061|Bacilli,3F4HR@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycH - - - - - - - - - - - YycH CCPPCCOK_01627 334390.LAF_0016 0.0 1174.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,3F45G@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 CCPPCCOK_01628 334390.LAF_0015 3.69e-168 469.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,3F4FB@33958|Lactobacillaceae 91061|Bacilli K response regulator yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CCPPCCOK_01631 334390.LAF_0014 3.39e-65 198.0 29P85@1|root,30A67@2|Bacteria,1U690@1239|Firmicutes,4IG05@91061|Bacilli,3F7C2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01632 334390.LAF_0013 1.79e-267 734.0 COG3104@1|root,COG3104@2|Bacteria,1UHXR@1239|Firmicutes,4ISA6@91061|Bacilli,3FBRN@33958|Lactobacillaceae 91061|Bacilli E Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CCPPCCOK_01633 334390.LAF_0012 0.0 868.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,3F4MW@33958|Lactobacillaceae 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C CCPPCCOK_01634 334390.LAF_0011 2.63e-99 288.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,3F68P@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N CCPPCCOK_01635 334390.LAF_0010 0.0 1306.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,3F3TY@33958|Lactobacillaceae 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 CCPPCCOK_01636 1203076.CAKF01000020_gene1592 1.33e-47 152.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,3F7CY@33958|Lactobacillaceae 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 CCPPCCOK_01637 334390.LAF_0008 6.56e-165 462.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3F66N@33958|Lactobacillaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB CCPPCCOK_01638 334390.LAF_0007 6.02e-64 195.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,3F6ZY@33958|Lactobacillaceae 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 CCPPCCOK_01639 334390.LAF_0006 0.0 1489.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,3F3YM@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV CCPPCCOK_01640 334390.LAF_0005 0.0 1277.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,3F48M@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim CCPPCCOK_01641 334390.LAF_0004 6.14e-259 711.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N CCPPCCOK_01642 334390.LAF_0003 1.45e-46 149.0 COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,3F803@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein YaaA yaaA - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 CCPPCCOK_01643 334390.LAF_0002 3.2e-264 724.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,3F3ZQ@33958|Lactobacillaceae 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 CCPPCCOK_01644 334390.LAF_0001 9.49e-317 863.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,3F3YA@33958|Lactobacillaceae 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N CCPPCCOK_01645 334390.LAF_1843 7.96e-21 82.4 COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,3F81W@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 CCPPCCOK_01646 334390.LAF_1842 2.64e-75 225.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,3F6GS@33958|Lactobacillaceae 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P CCPPCCOK_01647 334390.LAF_1841 4.99e-187 521.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,3F3SD@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP CCPPCCOK_01648 334390.LAF_1840 6.6e-184 513.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli,3F5WG@33958|Lactobacillaceae 91061|Bacilli S R3H domain protein jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H CCPPCCOK_01649 334390.LAF_1839 0.0 877.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,3F3WA@33958|Lactobacillaceae 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N CCPPCCOK_01650 334390.LAF_1838 0.0 1237.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,3F454@33958|Lactobacillaceae 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc CCPPCCOK_01651 334390.LAF_1837 1.03e-75 227.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,3F6YZ@33958|Lactobacillaceae 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL CCPPCCOK_01652 220668.45723562 0.0 1106.0 COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,4HBKG@91061|Bacilli,3F4XI@33958|Lactobacillaceae 91061|Bacilli D Anion-transporting ATPase arsA - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase CCPPCCOK_01653 220668.45723563 6.09e-293 801.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,3F5JS@33958|Lactobacillaceae 91061|Bacilli U Involved in arsenical resistance. Thought to form the channel of an arsenite pump arsB - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB CCPPCCOK_01654 220668.45723564 5.45e-68 206.0 29QJK@1|root,30BJ6@2|Bacteria,1U87M@1239|Firmicutes,4II5B@91061|Bacilli,3FANA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01655 220668.45723566 0.0 906.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,3F5SS@33958|Lactobacillaceae 91061|Bacilli P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain nox - 1.11.1.1 ko:K05910 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CCPPCCOK_01656 349123.Lreu23DRAFT_3295 1.35e-164 478.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 CCPPCCOK_01657 334390.LAF_0115 4.31e-293 799.0 COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,4HDKI@91061|Bacilli,3F3PA@33958|Lactobacillaceae 91061|Bacilli M cyclopropane-fatty-acyl-phospholipid synthase cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS CCPPCCOK_01658 1042156.CXIVA_19310 2.92e-05 46.6 COG1309@1|root,COG1309@2|Bacteria,1V89E@1239|Firmicutes,24JQ7@186801|Clostridia,36MDJ@31979|Clostridiaceae 186801|Clostridia K Transcriptional regulator C-terminal region - - - - - - - - - - - - TetR_C_8,TetR_N CCPPCCOK_01659 334390.LAF_0116 1.21e-224 622.0 COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,3F46E@33958|Lactobacillaceae 91061|Bacilli K AI-2E family transporter ydbI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport CCPPCCOK_01660 334390.LAF_0117 0.0 1090.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,3F3U6@33958|Lactobacillaceae 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS CCPPCCOK_01661 334390.LAF_0118 1.17e-105 305.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,3F6P0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC CCPPCCOK_01662 334390.LAF_0119 2.29e-273 748.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,3F3YV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp CCPPCCOK_01663 334390.LAF_0120 0.0 884.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,3F48P@33958|Lactobacillaceae 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 CCPPCCOK_01664 334390.LAF_0121 1.45e-223 619.0 COG1716@1|root,COG1716@2|Bacteria 2|Bacteria T histone H2A K63-linked ubiquitination hrpQ - 4.6.1.1 ko:K01768,ko:K03220,ko:K10914 ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111 M00332,M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko02044,ko03000 3.A.6.1 - - FHA,Yop-YscD_cpl,Yop-YscD_ppl,cNMP_binding CCPPCCOK_01665 334390.LAF_0122 0.0 954.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 CCPPCCOK_01666 334390.LAF_0124 6.13e-174 484.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,3F44Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt CCPPCCOK_01667 334390.LAF_0125 1.36e-50 160.0 COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,3F81F@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU06460 PurS CCPPCCOK_01668 334390.LAF_0126 4.87e-164 458.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,3F48D@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 CCPPCCOK_01669 334390.LAF_0127 0.0 1466.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,3F4IQ@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C CCPPCCOK_01670 334390.LAF_0128 0.0 963.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,3F3U7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran CCPPCCOK_01671 334390.LAF_0129 3.94e-250 686.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,3F4RT@33958|Lactobacillaceae 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C CCPPCCOK_01672 334390.LAF_0130 7.62e-138 389.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,3F3UN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N CCPPCCOK_01673 334390.LAF_0131 0.0 1016.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,3F4FD@33958|Lactobacillaceae 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS CCPPCCOK_01674 334390.LAF_0132 3.91e-307 836.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,3F4Z8@33958|Lactobacillaceae 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N CCPPCCOK_01675 334390.LAF_0135 1.15e-169 473.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,3F3SK@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 CCPPCCOK_01676 334390.LAF_0136 2.84e-285 779.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase araT - 2.6.1.57 ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 M00024,M00025,M00034,M00040,M00525 R00694,R00734,R01731,R04467,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CCPPCCOK_01677 334390.LAF_0137 1.67e-225 623.0 29NNF@1|root,309KD@2|Bacteria,1U59P@1239|Firmicutes,4IF13@91061|Bacilli,3F5AE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01678 334390.LAF_0138 1.52e-67 206.0 COG4633@1|root,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,4IRVT@91061|Bacilli,3FBQA@33958|Lactobacillaceae 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 CCPPCCOK_01679 334390.LAF_0139 3.81e-67 203.0 COG4633@1|root,COG4633@2|Bacteria,1W06G@1239|Firmicutes,4HZAG@91061|Bacilli,3F7FA@33958|Lactobacillaceae 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 CCPPCCOK_01680 334390.LAF_0140 0.0 1186.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copA - 3.6.3.3,3.6.3.5,3.6.3.54 ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 - - Cupredoxin_1,E1-E2_ATPase,Hydrolase CCPPCCOK_01681 1423814.HMPREF0549_0026 3.1e-37 139.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 CCPPCCOK_01682 334390.LAF_0141 6.87e-117 333.0 COG3613@1|root,COG3613@2|Bacteria,1VETR@1239|Firmicutes,4HNTN@91061|Bacilli,3F6C3@33958|Lactobacillaceae 91061|Bacilli F nucleoside 2-deoxyribosyltransferase yejD - 2.4.2.6 ko:K08728 ko00240,map00240 - R02806 RC00063 ko00000,ko00001,ko01000 - - - Nuc_deoxyrib_tr CCPPCCOK_01683 334390.LAF_1734 1.24e-160 449.0 COG0664@1|root,COG0664@2|Bacteria,1UXDW@1239|Firmicutes,4HCRG@91061|Bacilli,3F5KR@33958|Lactobacillaceae 91061|Bacilli K Crp-like helix-turn-helix domain rcfB - - - - - - - - - - - HTH_Crp_2 CCPPCCOK_01684 334390.LAF_1733 7.03e-306 834.0 COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,4HDCE@91061|Bacilli,3F3MP@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF2088) larA - 5.1.2.1 ko:K22373 ko00620,map00620 - R01450 RC00519 ko00000,ko00001,ko01000 - - - DUF2088 CCPPCCOK_01685 334390.LAF_1732 2.36e-168 471.0 COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,4HBMK@91061|Bacilli,3F526@33958|Lactobacillaceae 91061|Bacilli S AIR carboxylase larB - - ko:K06898 - - - - ko00000 - - - AIRC CCPPCCOK_01686 334390.LAF_1731 1.3e-301 825.0 COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,4HC7I@91061|Bacilli,3F408@33958|Lactobacillaceae 91061|Bacilli S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes larC - 4.99.1.12 ko:K09121 - - - - ko00000,ko01000 - - - DUF111 CCPPCCOK_01687 334390.LAF_1730 1.33e-166 466.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F42H@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP CCPPCCOK_01688 334390.LAF_1729 3.27e-191 531.0 COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,4HAZT@91061|Bacilli,3F3Z9@33958|Lactobacillaceae 91061|Bacilli S NAD synthase larE - - ko:K06864 - - - - ko00000 - - - NAD_synthase CCPPCCOK_01689 334390.LAF_1728 5.27e-237 652.0 COG2042@1|root,COG3376@2|Bacteria,1TSSI@1239|Firmicutes,4HEUV@91061|Bacilli,3F4YV@33958|Lactobacillaceae 91061|Bacilli U High-affinity nickel-transport protein hoxN - - ko:K07241 - - - - ko00000,ko02000 2.A.52.1 - - NicO CCPPCCOK_01690 1203076.CAKF01000017_gene1766 1.09e-77 242.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport - - - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport CCPPCCOK_01691 1293597.BN147_02525 9.36e-110 330.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 CCPPCCOK_01692 1158607.UAU_01381 9.21e-19 80.1 COG2161@1|root,COG2161@2|Bacteria,1TVB9@1239|Firmicutes,4I968@91061|Bacilli,4B3TC@81852|Enterococcaceae 91061|Bacilli D Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox CCPPCCOK_01693 1437606.BBOH_1213 3.69e-31 111.0 COG4115@1|root,COG4115@2|Bacteria 2|Bacteria D mRNA cleavage - - - ko:K19158 - - - - ko00000,ko01000,ko02048 - - - YoeB_toxin CCPPCCOK_01694 334390.LAF_1457 5.23e-235 650.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC7U@91061|Bacilli,3F4FE@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC - - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 CCPPCCOK_01696 334390.LAF_1456 4.35e-247 686.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,3F3VX@33958|Lactobacillaceae 91061|Bacilli C Na H antiporter NhaC nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter CCPPCCOK_01698 334390.LAF_1455 2.29e-96 285.0 COG1834@1|root,COG1834@2|Bacteria,1TRPV@1239|Firmicutes,4H9YU@91061|Bacilli,3FA93@33958|Lactobacillaceae 91061|Bacilli E Amidinotransferase - - 3.5.3.18 ko:K01482 - - - - ko00000,ko01000,ko04147 - - - Amidinotransf CCPPCCOK_01699 334390.LAF_1453 3.19e-115 330.0 COG3760@1|root,COG3760@2|Bacteria,1V29H@1239|Firmicutes,4HP8F@91061|Bacilli,3F6ZD@33958|Lactobacillaceae 91061|Bacilli S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit CCPPCCOK_01700 334390.LAF_1452 0.0 1074.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,3F3XB@33958|Lactobacillaceae 91061|Bacilli Q Multicopper oxidase sufI - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 CCPPCCOK_01701 334390.LAF_1451 1.28e-67 205.0 COG1959@1|root,COG1959@2|Bacteria 2|Bacteria K 2 iron, 2 sulfur cluster binding - - - - - - - - - - - - Rrf2 CCPPCCOK_01702 334390.LAF_1450 1.03e-120 346.0 COG2085@1|root,COG2085@2|Bacteria,1V35D@1239|Firmicutes,4HFSW@91061|Bacilli,3F5EP@33958|Lactobacillaceae 91061|Bacilli S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored CCPPCCOK_01703 334390.LAF_1449 1.22e-154 435.0 COG0500@1|root,COG2226@2|Bacteria,1UHIX@1239|Firmicutes,4HFT8@91061|Bacilli,3F695@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 CCPPCCOK_01705 334390.LAF_1447 2e-135 384.0 COG1266@1|root,COG1266@2|Bacteria,1VBYM@1239|Firmicutes,4HM2K@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi CCPPCCOK_01706 334390.LAF_1446 5.3e-130 368.0 COG0350@1|root,COG0350@2|Bacteria,1V2MB@1239|Firmicutes,4HJGF@91061|Bacilli,3FBD8@33958|Lactobacillaceae 91061|Bacilli L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N CCPPCCOK_01707 575594.ACOH01000002_gene989 6.1e-102 309.0 COG0477@1|root,COG2814@2|Bacteria,1UJ0G@1239|Firmicutes,4ITTG@91061|Bacilli 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CCPPCCOK_01708 575594.ACOH01000002_gene989 9.79e-62 201.0 COG0477@1|root,COG2814@2|Bacteria,1UJ0G@1239|Firmicutes,4ITTG@91061|Bacilli 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CCPPCCOK_01709 334390.LAF_1445 2.39e-131 372.0 COG1846@1|root,COG1846@2|Bacteria,1VQ2Q@1239|Firmicutes,4HS36@91061|Bacilli 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 CCPPCCOK_01710 334390.LAF_1444 4.82e-277 760.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr CCPPCCOK_01711 334390.LAF_1443 2.57e-135 382.0 2AYWY@1|root,3354X@2|Bacteria,1VUSY@1239|Firmicutes,4HVEY@91061|Bacilli,3FC0S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01712 334390.LAF_1442 1.76e-113 325.0 COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli,3F5WI@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin CCPPCCOK_01713 334390.LAF_1441 0.0 1070.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,3F3ZJ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn CCPPCCOK_01714 1203076.CAKF01000006_gene499 2.89e-44 147.0 COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,3F7SB@33958|Lactobacillaceae 91061|Bacilli S Belongs to the HesB IscA family yneR - - - - - - - - - - - Fe-S_biosyn CCPPCCOK_01715 334390.LAF_1440 4.28e-179 499.0 COG0431@1|root,COG0431@2|Bacteria,1VBJA@1239|Firmicutes,4HSVK@91061|Bacilli,3F41J@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red CCPPCCOK_01716 334390.LAF_1439 0.0 994.0 COG2918@1|root,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,3F506@33958|Lactobacillaceae 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase CCPPCCOK_01717 334390.LAF_1438 1.29e-205 570.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli,3F4M2@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily - - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N CCPPCCOK_01718 334390.LAF_1437 3.12e-135 382.0 COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HE2X@91061|Bacilli,3F5U4@33958|Lactobacillaceae 91061|Bacilli S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox CCPPCCOK_01719 334390.LAF_1436 5.17e-83 245.0 2EGZM@1|root,33ARR@2|Bacteria,1VNS7@1239|Firmicutes,4HSZW@91061|Bacilli,3F83W@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4828) - - - - - - - - - - - - DUF4828 CCPPCCOK_01720 334390.LAF_1435 4.94e-244 670.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,3F4EV@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase mocA - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CCPPCCOK_01721 334390.LAF_1434 1.42e-305 834.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,3F4K8@33958|Lactobacillaceae 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C CCPPCCOK_01723 334390.LAF_1433 3.95e-98 285.0 COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,3F4GH@33958|Lactobacillaceae 91061|Bacilli S Teichoic acid glycosylation protein gtcA - - - - - - - - - - - GtrA CCPPCCOK_01724 334390.LAF_1432 1.66e-101 294.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli,3F6HY@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin ykuP - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 CCPPCCOK_01725 334390.LAF_1431 1.17e-214 591.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,3F3MK@33958|Lactobacillaceae 91061|Bacilli E Methionine Aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 CCPPCCOK_01726 334390.LAF_1430 0.0 1909.0 COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,4HBY6@91061|Bacilli,3F3NY@33958|Lactobacillaceae 91061|Bacilli M Sulfatase XK27_08315 - - - - - - - - - - - Sulfatase CCPPCCOK_01727 334390.LAF_1429 5.86e-192 535.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,3F4TC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0761 family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB CCPPCCOK_01728 334390.LAF_1428 4.37e-43 140.0 2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF2922) - - - - - - - - - - - - DUF2922 CCPPCCOK_01730 334390.LAF_1426 2.05e-188 524.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,3F4BY@33958|Lactobacillaceae 91061|Bacilli S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX CCPPCCOK_01731 334390.LAF_1425 1.73e-152 429.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HCBG@91061|Bacilli,3F51J@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase rfbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K13012,ko:K19428 - - - - ko00000,ko01000,ko01005 - - - Bac_transf,CoA_binding_3 CCPPCCOK_01732 334390.LAF_1424 4.02e-190 526.0 COG1442@1|root,COG1442@2|Bacteria,1U6EG@1239|Firmicutes,4HG4F@91061|Bacilli,3F539@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF4422) cps1D - - - - - - - - - - - DUF4422 CCPPCCOK_01733 349123.Lreu23DRAFT_4284 4.76e-117 353.0 2DN9M@1|root,32W9S@2|Bacteria,1VDRM@1239|Firmicutes,4HRQ0@91061|Bacilli,3F6CA@33958|Lactobacillaceae 91061|Bacilli - - cps3F - - - - - - - - - - - - CCPPCCOK_01734 944562.HMPREF9102_0199 1.34e-39 141.0 COG3944@1|root,COG3944@2|Bacteria,1W5Q7@1239|Firmicutes,4HZIW@91061|Bacilli,3F84M@33958|Lactobacillaceae 91061|Bacilli M biosynthesis protein - - - - - - - - - - - - Wzz CCPPCCOK_01735 334390.LAF_1416 4.65e-279 761.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,4HB5F@91061|Bacilli,3F52G@33958|Lactobacillaceae 91061|Bacilli M UDP-galactopyranose mutase glf - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 CCPPCCOK_01736 334390.LAF_1415 4.12e-255 709.0 COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HC84@91061|Bacilli,3F48Q@33958|Lactobacillaceae 91061|Bacilli S Membrane protein involved in the export of O-antigen and teichoic acid cps1C - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C CCPPCCOK_01737 557436.Lreu_1368 2.39e-88 276.0 COG3274@1|root,COG3274@2|Bacteria,1TX6V@1239|Firmicutes,4HVSI@91061|Bacilli,3F778@33958|Lactobacillaceae 91061|Bacilli S enterobacterial common antigen metabolic process - - - - - - - - - - - - Acyl_transf_3 CCPPCCOK_01738 557436.Lreu_1367 3.51e-92 291.0 COG1705@1|root,COG5263@1|root,COG1705@2|Bacteria,COG5263@2|Bacteria,1UJIC@1239|Firmicutes,4ITA9@91061|Bacilli,3F6PF@33958|Lactobacillaceae 91061|Bacilli M NLP P60 protein - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 CCPPCCOK_01740 557436.Lreu_1365 4.93e-76 242.0 COG5263@1|root,COG5632@1|root,COG5263@2|Bacteria,COG5632@2|Bacteria,1UJIC@1239|Firmicutes,4ITA9@91061|Bacilli,3F6PF@33958|Lactobacillaceae 91061|Bacilli M NLP P60 protein - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 CCPPCCOK_01741 557436.Lreu_1364 3.99e-81 266.0 COG0791@1|root,COG5263@1|root,COG0791@2|Bacteria,COG5263@2|Bacteria,1UJIC@1239|Firmicutes,4ITA9@91061|Bacilli,3F6PF@33958|Lactobacillaceae 91061|Bacilli M NLP P60 protein - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 CCPPCCOK_01742 557436.Lreu_1363 8.03e-10 63.2 29PQC@1|root,30ANH@2|Bacteria,1U6WM@1239|Firmicutes,4IGQU@91061|Bacilli,3F8MS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01743 334390.LAF_1409 4.64e-204 566.0 COG1216@1|root,COG1216@2|Bacteria,1UHWE@1239|Firmicutes,4ISA4@91061|Bacilli,3F3JX@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 2 family protein yfdH - - ko:K12999 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 CCPPCCOK_01744 334390.LAF_1408 8.36e-216 601.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport CCPPCCOK_01745 334390.LAF_1407 2.48e-209 581.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3F3X7@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 ykoT - - - - - - - - - - - Glycos_transf_2 CCPPCCOK_01746 334390.LAF_1404 0.0 1055.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,3F489@33958|Lactobacillaceae 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C CCPPCCOK_01747 1069534.LRC_01160 2.62e-119 355.0 COG0438@1|root,COG0438@2|Bacteria,1V8J0@1239|Firmicutes,4HVPH@91061|Bacilli,3FBD0@33958|Lactobacillaceae 91061|Bacilli M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - CCPPCCOK_01748 353496.LBU_1592 3.67e-127 371.0 COG1216@1|root,COG1216@2|Bacteria,1V4NS@1239|Firmicutes,4HHDW@91061|Bacilli,3F6P7@33958|Lactobacillaceae 91061|Bacilli S Glycosyltransferase like family 2 - - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 CCPPCCOK_01749 1221537.B807_199 3.11e-100 322.0 COG4485@1|root,COG4485@2|Bacteria,1V83S@1239|Firmicutes,4HY51@91061|Bacilli,3F5ER@33958|Lactobacillaceae 91061|Bacilli S Bacterial membrane protein, YfhO - - - - - - - - - - - - - CCPPCCOK_01750 334390.LAF_1401 5.59e-221 609.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,3F3R6@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd CCPPCCOK_01751 334390.LAF_1400 2.08e-84 249.0 COG1725@1|root,COG1725@2|Bacteria,1VAC6@1239|Firmicutes,4HKVW@91061|Bacilli,3F721@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, GntR family - - - - - - - - - - - - GntR CCPPCCOK_01752 334390.LAF_1399 6.66e-201 556.0 COG1131@1|root,COG1131@2|Bacteria,1TS5Y@1239|Firmicutes,4HBUA@91061|Bacilli,3F4BF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CCPPCCOK_01755 334390.LAF_1396 2.77e-314 854.0 COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HAB0@91061|Bacilli,3F3S7@33958|Lactobacillaceae 91061|Bacilli S ATP-grasp enzyme yxbA - 6.3.1.12 ko:K17810 - - - - ko00000,ko01000 - - - CPSase_L_D2,Dala_Dala_lig_C CCPPCCOK_01756 334390.LAF_1395 1.81e-207 574.0 COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,4HDIE@91061|Bacilli,3F5JP@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA CCPPCCOK_01757 334390.LAF_1394 2.02e-174 488.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,3F4SE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer CCPPCCOK_01758 334390.LAF_1393 1.15e-182 506.0 COG1482@1|root,COG1482@2|Bacteria,1VWMM@1239|Firmicutes,4HX8A@91061|Bacilli,3F62Q@33958|Lactobacillaceae 91061|Bacilli G MucBP domain - - - - - - - - - - - - MucBP CCPPCCOK_01759 334390.LAF_1392 8.07e-126 359.0 COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,4HFPD@91061|Bacilli,3FCAQ@33958|Lactobacillaceae 91061|Bacilli S Pfam:DUF3816 - - - - - - - - - - - - ECF_trnsprt CCPPCCOK_01760 334390.LAF_1391 0.0 921.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP nadC2 - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase CCPPCCOK_01761 334390.LAF_1390 8.61e-143 402.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli,3F41F@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family pncA - - - - - - - - - - - Isochorismatase CCPPCCOK_01762 334390.LAF_1389 1.44e-165 463.0 COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,1UZ4E@1239|Firmicutes,4IPMJ@91061|Bacilli,3FBCZ@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX CCPPCCOK_01763 334390.LAF_1388 0.0 1399.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F3K9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the ClpA ClpB family clpE - - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR CCPPCCOK_01764 565653.EGBG_00742 2.41e-07 49.7 2EI19@1|root,33BSS@2|Bacteria,1VKXC@1239|Firmicutes,4HR2E@91061|Bacilli,4B496@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01765 334390.LAF_1386 8.72e-53 166.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,3F6XQ@33958|Lactobacillaceae 91061|Bacilli G phosphocarrier protein HPR ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr CCPPCCOK_01766 334390.LAF_1385 0.0 1114.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,3F3MS@33958|Lactobacillaceae 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C CCPPCCOK_01767 334390.LAF_1384 5.62e-294 802.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,3F4H5@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein pimB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 CCPPCCOK_01768 334390.LAF_1383 2.21e-254 696.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli,3F47X@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 2.4.1.208 ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 - R05164,R10865 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 CCPPCCOK_01769 334390.LAF_1382 3.97e-231 637.0 COG0392@1|root,COG0392@2|Bacteria,1UY7Z@1239|Firmicutes,4HCG6@91061|Bacilli,3F3UR@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM CCPPCCOK_01770 334390.LAF_1381 1.14e-52 165.0 COG4703@1|root,COG4703@2|Bacteria,1U6NV@1239|Firmicutes,4IGFT@91061|Bacilli,3F87U@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1797) - - - - - - - - - - - - DUF1797 CCPPCCOK_01771 525318.HMPREF0497_2525 0.0 1145.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family cidC - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - iSB619.SA_RS13340 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CCPPCCOK_01772 797515.HMPREF9103_01752 0.0 881.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR3 - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CCPPCCOK_01774 1121105.ATXL01000044_gene114 0.0 995.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,4B0EI@81852|Enterococcaceae 91061|Bacilli S MCRA family mycA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA CCPPCCOK_01775 334390.LAF_1720 4.6e-63 205.0 COG2271@1|root,COG2271@2|Bacteria,1TS33@1239|Firmicutes,4HBVJ@91061|Bacilli,3F4E6@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator Superfamily glpT - - ko:K02445 - - - - ko00000,ko02000 2.A.1.4.3 - - MFS_1 CCPPCCOK_01776 334390.LAF_1719 3.45e-175 493.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli,3F4HV@33958|Lactobacillaceae 91061|Bacilli O prohibitin homologues hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 CCPPCCOK_01778 334390.LAF_1717 2.16e-98 286.0 COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4HNHG@91061|Bacilli,3F4Z0@33958|Lactobacillaceae 91061|Bacilli T universal stress protein uspA3 - - - - - - - - - - - Usp CCPPCCOK_01779 334390.LAF_1716 6.25e-78 233.0 29P7S@1|root,30A5V@2|Bacteria,1U68K@1239|Firmicutes,4IFZG@91061|Bacilli,3F7B2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01780 1231336.L248_1444 1.25e-09 63.2 29V33@1|root,30GGE@2|Bacteria,1UFZH@1239|Firmicutes,4IF1H@91061|Bacilli,3F5BQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01781 334390.LAF_1714 1.92e-203 563.0 2E39Q@1|root,32Y99@2|Bacteria,1VQQ8@1239|Firmicutes,4HRY1@91061|Bacilli,3F4UX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01782 334390.LAF_1713 2.22e-98 285.0 COG1396@1|root,COG1396@2|Bacteria,1VEC4@1239|Firmicutes,4HM2F@91061|Bacilli,3F654@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_3 CCPPCCOK_01783 334390.LAF_1712 5.3e-240 658.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 CCPPCCOK_01784 334390.LAF_1711 5.18e-92 271.0 COG1764@1|root,COG1764@2|Bacteria,1VY9T@1239|Firmicutes,4HXI7@91061|Bacilli,3F7CX@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC CCPPCCOK_01785 334390.LAF_1710 7.9e-246 674.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,3F49I@33958|Lactobacillaceae 91061|Bacilli H Bacterial lipoate protein ligase C-terminus lplL - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C CCPPCCOK_01788 405566.lhv_1986 5.56e-214 590.0 COG0524@1|root,COG0524@2|Bacteria,1UIWH@1239|Firmicutes,4HI23@91061|Bacilli,3F5HW@33958|Lactobacillaceae 91061|Bacilli G Belongs to the carbohydrate kinase PfkB family - - - - - - - - - - - - PfkB CCPPCCOK_01789 405566.lhv_1985 0.0 870.0 COG1457@1|root,COG1457@2|Bacteria,1TRAH@1239|Firmicutes,4IRPE@91061|Bacilli 91061|Bacilli F Belongs to the purine-cytosine permease (2.A.39) family - - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur CCPPCCOK_01790 405566.lhv_1984 5.15e-246 675.0 COG1397@1|root,COG1397@2|Bacteria,1U2AQ@1239|Firmicutes,4HIXT@91061|Bacilli,3F4WI@33958|Lactobacillaceae 91061|Bacilli O ADP-ribosylglycohydrolase - - - - - - - - - - - - ADP_ribosyl_GH CCPPCCOK_01791 334390.LAF_1735 0.0 1106.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,3F3MS@33958|Lactobacillaceae 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C CCPPCCOK_01792 334390.LAF_1736 0.0 867.0 COG0738@1|root,COG0738@2|Bacteria,1TQ1K@1239|Firmicutes,4HTTC@91061|Bacilli,3F3U4@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator Superfamily fucP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 CCPPCCOK_01793 334390.LAF_1737 8.61e-89 260.0 COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,4HIFW@91061|Bacilli,3F6GA@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose rbsD - 5.4.99.62 ko:K06726 ko02010,map02010 - R08247 RC02247 ko00000,ko00001,ko01000 - - - RbsD_FucU CCPPCCOK_01794 334390.LAF_1738 1.59e-213 590.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,3F3S5@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB,Rib_5-P_isom_A CCPPCCOK_01795 334390.LAF_1739 5.79e-218 602.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,3F4PP@33958|Lactobacillaceae 91061|Bacilli K sugar-binding domain protein deoR GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05346 - - - - ko00000,ko03000 - - - HTH_23,HTH_24,HTH_Crp_2,MarR_2,Sigma70_r4,Sugar-bind CCPPCCOK_01796 334390.LAF_1740 2.05e-147 416.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,3F4M3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC,NUDIX CCPPCCOK_01797 334390.LAF_1741 1.49e-255 699.0 28JDC@1|root,2Z97R@2|Bacteria,1UE66@1239|Firmicutes,4IF0R@91061|Bacilli,3F59E@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4432) - - - - - - - - - - - - DUF4432 CCPPCCOK_01798 334390.LAF_1742 2.57e-224 618.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,3F3S5@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB CCPPCCOK_01799 334390.LAF_1743 0.0 902.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HF7Z@91061|Bacilli,3FCCF@33958|Lactobacillaceae 91061|Bacilli G PTS system Galactitol-specific IIC component - - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT CCPPCCOK_01800 334390.LAF_1744 1.65e-241 663.0 COG1609@1|root,COG1609@2|Bacteria,1TQSY@1239|Firmicutes,4HAJI@91061|Bacilli,3F51M@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor - - - ko:K02525 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3,Peripla_BP_4 CCPPCCOK_01801 334390.LAF_1745 0.0 976.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HA0N@91061|Bacilli,3F4J0@33958|Lactobacillaceae 91061|Bacilli E Amino Acid potE - - - - - - - - - - - AA_permease_2 CCPPCCOK_01802 334390.LAF_1614 5.12e-266 730.0 COG0477@1|root,COG2814@2|Bacteria,1TRNU@1239|Firmicutes,4HCSX@91061|Bacilli,3FCA6@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1,Sugar_tr CCPPCCOK_01803 334390.LAF_1613 1.73e-271 745.0 COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,3F582@33958|Lactobacillaceae 91061|Bacilli P Natural resistance-associated macrophage protein ycsG - - - - - - - - - - - Nramp CCPPCCOK_01804 334390.LAF_1612 5.76e-163 457.0 COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,4H9PF@91061|Bacilli,3F3Q3@33958|Lactobacillaceae 91061|Bacilli S LamB/YcsF family - - - ko:K07160 - - - - ko00000 - - - LamB_YcsF CCPPCCOK_01805 334390.LAF_1611 0.0 890.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,3F3PT@33958|Lactobacillaceae 91061|Bacilli I Acetyl-CoA carboxylase biotin carboxylase subunit accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 CCPPCCOK_01806 334390.LAF_1610 1.59e-86 255.0 COG0511@1|root,COG0511@2|Bacteria,1VH23@1239|Firmicutes,4HQHP@91061|Bacilli,3F7QZ@33958|Lactobacillaceae 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA - - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl CCPPCCOK_01807 334390.LAF_1609 1.42e-244 671.0 COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,3F545@33958|Lactobacillaceae 91061|Bacilli E Allophanate hydrolase subunit 2 kipA - - ko:K06350 - - - - ko00000 - - - CT_A_B CCPPCCOK_01808 334390.LAF_1608 2.19e-172 481.0 COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4HHJJ@91061|Bacilli,3F64P@33958|Lactobacillaceae 91061|Bacilli E Allophanate hydrolase subunit 1 kipI - - ko:K06351 - - - - ko00000 - - - CT_C_D CCPPCCOK_01809 334390.LAF_1607 2.31e-95 278.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,3F7ID@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 CCPPCCOK_01811 334390.LAF_0785 1.11e-281 769.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,3F3RF@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 CCPPCCOK_01812 1121333.JMLH01000072_gene1791 2.36e-35 131.0 COG1277@1|root,COG1277@2|Bacteria,1UYSH@1239|Firmicutes 1239|Firmicutes S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - - - - - - - - - - ABC2_membrane_2 CCPPCCOK_01813 1121874.KB892377_gene906 2.27e-36 131.0 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,3VUDJ@526524|Erysipelotrichia 526524|Erysipelotrichia T Response regulator receiver domain protein - - - - - - - - - - - - Response_reg,Trans_reg_C CCPPCCOK_01814 1138822.PL11_10710 1.59e-29 114.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut CCPPCCOK_01815 334390.LAF_1200 2.94e-195 541.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,3F47B@33958|Lactobacillaceae 91061|Bacilli S hydrolase yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 CCPPCCOK_01816 334390.LAF_1199 0.0 935.0 COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli,3F492@33958|Lactobacillaceae 91061|Bacilli J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI CCPPCCOK_01828 1300150.EMQU_0817 8.21e-07 50.1 COG1309@1|root,COG1309@2|Bacteria,1VH11@1239|Firmicutes,4IQHV@91061|Bacilli,4B6TC@81852|Enterococcaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_8 CCPPCCOK_01829 1140003.I573_00015 8.34e-20 84.3 COG2076@1|root,COG2076@2|Bacteria,1VEUF@1239|Firmicutes,4HNJX@91061|Bacilli,4B341@81852|Enterococcaceae 91061|Bacilli U Small Multidrug Resistance protein ebrB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03297,ko:K11814,ko:K11815 - M00710 - - ko00000,ko00002,ko02000 2.A.7.1,2.A.7.1.6 - - Multi_Drug_Res CCPPCCOK_01830 334390.LAF_1378 8.27e-184 512.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HD16@91061|Bacilli,3F4YD@33958|Lactobacillaceae 91061|Bacilli ET Bacterial periplasmic substrate-binding proteins artP - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CCPPCCOK_01831 334390.LAF_1377 1.11e-145 412.0 COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease arpJ - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1,SBP_bac_3 CCPPCCOK_01832 334390.LAF_1376 0.0 1501.0 COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli,3F435@33958|Lactobacillaceae 91061|Bacilli F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD CCPPCCOK_01833 334390.LAF_1375 2.99e-144 405.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli,3F46H@33958|Lactobacillaceae 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM CCPPCCOK_01834 334390.LAF_1374 1.03e-206 572.0 COG0719@1|root,COG0719@2|Bacteria,1U5WR@1239|Firmicutes,4IFK7@91061|Bacilli,3F6MK@33958|Lactobacillaceae 91061|Bacilli O Uncharacterized protein family (UPF0051) - - - - - - - - - - - - UPF0051 CCPPCCOK_01835 334390.LAF_1373 1.85e-301 824.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HCX6@91061|Bacilli,3FC8X@33958|Lactobacillaceae 91061|Bacilli F Permease - - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease CCPPCCOK_01836 334390.LAF_1372 1.13e-251 691.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F5ST@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase adh - 1.1.1.1 ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703 RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CCPPCCOK_01837 334390.LAF_1371 5.54e-97 292.0 COG1388@1|root,COG1388@2|Bacteria,1V773@1239|Firmicutes,4HIJG@91061|Bacilli,3F3JQ@33958|Lactobacillaceae 91061|Bacilli M LysM domain protein - - - - - - - - - - - - LysM,SLAP CCPPCCOK_01838 334390.LAF_1370 1.47e-111 321.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,3F6A3@33958|Lactobacillaceae 91061|Bacilli I Thioesterase superfamily ykhA - 3.1.2.20 ko:K01073 - - - - ko00000,ko01000 - - - 4HBT CCPPCCOK_01839 334390.LAF_1369 2.79e-102 295.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli,3F7DR@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp1 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 CCPPCCOK_01840 334390.LAF_1368 1.48e-117 338.0 COG1309@1|root,COG1309@2|Bacteria,1U5TP@1239|Firmicutes,4IFHQ@91061|Bacilli,3F6HI@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, TetR family - - - - - - - - - - - - TetR_N CCPPCCOK_01841 334390.LAF_1606 5.09e-107 308.0 2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,4IG6C@91061|Bacilli,3F7QU@33958|Lactobacillaceae 91061|Bacilli S Psort location Cytoplasmic, score - - - - - - - - - - - - - CCPPCCOK_01842 334390.LAF_1605 0.0 983.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HFGA@91061|Bacilli,3FCBJ@33958|Lactobacillaceae 91061|Bacilli L impB/mucB/samB family C-terminal domain umuC - - ko:K03502 - - - - ko00000,ko03400 - - - IMS,IMS_C CCPPCCOK_01843 334390.LAF_1604 8.45e-123 350.0 COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,4HMP7@91061|Bacilli,3F6WQ@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 CCPPCCOK_01844 334390.LAF_1603 3.07e-135 383.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4I2AJ@91061|Bacilli,3F65T@33958|Lactobacillaceae 91061|Bacilli NU mannosyl-glycoprotein - - - - - - - - - - - - Glucosaminidase CCPPCCOK_01845 334390.LAF_1602 5.59e-250 685.0 COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,4HAEC@91061|Bacilli,3F40A@33958|Lactobacillaceae 91061|Bacilli F aspartate--ammonia ligase asnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 - R00483 RC00010 ko00000,ko00001,ko01000 - - - AsnA CCPPCCOK_01846 1423780.LOT_1680 8.61e-22 94.0 COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,4HEXU@91061|Bacilli,3FBF3@33958|Lactobacillaceae 91061|Bacilli S HAD-hyrolase-like yfnB - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 CCPPCCOK_01847 334390.LAF_0059 1.01e-187 526.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon CCPPCCOK_01848 334390.LAF_1543 2.51e-158 443.0 COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,4HH06@91061|Bacilli,3F405@33958|Lactobacillaceae 91061|Bacilli K iron dependent repressor mntR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA CCPPCCOK_01849 334390.LAF_1542 2.09e-41 135.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7FW@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein cspC - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CCPPCCOK_01850 334390.LAF_1541 3.88e-161 453.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE CCPPCCOK_01851 334390.LAF_1540 8.17e-107 308.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F63I@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 CCPPCCOK_01852 334390.LAF_1539 3.13e-149 421.0 COG0671@1|root,COG0671@2|Bacteria,1VY85@1239|Firmicutes,4HXM4@91061|Bacilli,3F4DD@33958|Lactobacillaceae 91061|Bacilli I phosphatase - - - - - - - - - - - - PAP2 CCPPCCOK_01853 334390.LAF_1538 1.2e-199 552.0 COG0657@1|root,COG0657@2|Bacteria,1V7DQ@1239|Firmicutes,4HK24@91061|Bacilli,3FBDR@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 CCPPCCOK_01855 334390.LAF_1536 0.0 962.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid lysP - - ko:K03293,ko:K11733 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.2 - - AA_permease CCPPCCOK_01856 334390.LAF_1535 4.69e-151 424.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F488@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase dgk2 - - - - - - - - - - - dNK CCPPCCOK_01862 1302286.BAOT01000038_gene1514 1.01e-14 72.4 COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,4HAU2@91061|Bacilli,3FC9R@33958|Lactobacillaceae 91061|Bacilli IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG1 - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CCPPCCOK_01863 1345023.M467_05945 5.05e-58 187.0 COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,4HAU2@91061|Bacilli 91061|Bacilli IQ reductase - - - - - - - - - - - - adh_short_C2 CCPPCCOK_01864 334390.LAF_1534 7.14e-191 530.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli,3F510@33958|Lactobacillaceae 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA CCPPCCOK_01865 797515.HMPREF9103_01722 2.89e-24 97.1 COG4721@1|root,COG4721@2|Bacteria,1V2RP@1239|Firmicutes,4HGBA@91061|Bacilli,3FBNY@33958|Lactobacillaceae 91061|Bacilli S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt CCPPCCOK_01866 334390.LAF_1532 6.8e-93 273.0 COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,4HHG6@91061|Bacilli,3F6M6@33958|Lactobacillaceae 91061|Bacilli S Thiamine-precursor transporter protein (ThiW) thiW - - - - - - - - - - - ThiW CCPPCCOK_01867 1122149.BACN01000028_gene1588 1e-60 191.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,3F69R@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator, MerR family rmeB - - - - - - - - - - - MerR_1 CCPPCCOK_01868 334390.LAF_0058 5.92e-58 181.0 COG1943@1|root,COG1943@2|Bacteria,1V4ET@1239|Firmicutes,4HH13@91061|Bacilli,3F7IF@33958|Lactobacillaceae 91061|Bacilli L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp CCPPCCOK_01887 334390.LAF_0418 1.02e-102 297.0 COG1846@1|root,COG1846@2|Bacteria,1TTKV@1239|Firmicutes,4IG35@91061|Bacilli,3F7IS@33958|Lactobacillaceae 91061|Bacilli K Winged helix-turn-helix DNA-binding - - - - - - - - - - - - MarR CCPPCCOK_01888 334390.LAF_0419 0.0 1086.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ycfI - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CCPPCCOK_01889 334390.LAF_0420 0.0 1165.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yfiC - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CCPPCCOK_01890 334390.LAF_0421 1.31e-245 674.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,3FBDZ@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase ampC - - - - - - - - - - - Beta-lactamase CCPPCCOK_01891 334390.LAF_0422 0.0 988.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N CCPPCCOK_01892 334390.LAF_0423 2.31e-63 194.0 29PEK@1|root,315VH@2|Bacteria,1U6YW@1239|Firmicutes,4IGT4@91061|Bacilli,3F8QZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CCPPCCOK_01893 334390.LAF_0424 7.49e-181 502.0 COG3442@1|root,COG3442@2|Bacteria,1UYMA@1239|Firmicutes,4HEXH@91061|Bacilli,3FBI0@33958|Lactobacillaceae 91061|Bacilli S CobB/CobQ-like glutamine amidotransferase domain - - - ko:K07009 - - - - ko00000 - - iSB619.SA_RS09800 GATase_3 CCPPCCOK_01894 334390.LAF_0425 0.0 904.0 COG0770@1|root,COG0770@2|Bacteria,1TRG9@1239|Firmicutes,4HAMY@91061|Bacilli,3FBS5@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF1727) murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M CCPPCCOK_01895 334390.LAF_0426 1.78e-139 394.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,3F4UE@33958|Lactobacillaceae 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK CCPPCCOK_01896 334390.LAF_0427 1.53e-207 580.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,3F3Q0@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 CCPPCCOK_01897 334390.LAF_0428 1.92e-203 563.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,3F460@33958|Lactobacillaceae 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS CCPPCCOK_01898 334390.LAF_0429 2.77e-249 684.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,3F3T1@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC CCPPCCOK_01899 334390.LAF_0430 9e-294 802.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,3F4C1@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT CCPPCCOK_01900 334390.LAF_0431 3.86e-149 419.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,3F4M0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase CCPPCCOK_01901 334390.LAF_0432 8.52e-254 698.0 COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,4HCP3@91061|Bacilli,3F3M9@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibE - - - - - - - - - - - YibE_F CCPPCCOK_01902 334390.LAF_0433 1.35e-165 465.0 COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,4HBKX@91061|Bacilli,3F3S6@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibF - - - - - - - - - - - YibE_F CCPPCCOK_01903 334390.LAF_0434 1.1e-295 808.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,3F3UJ@33958|Lactobacillaceae 91061|Bacilli F Permease pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease CCPPCCOK_01904 334390.LAF_0435 5.66e-168 469.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,3F3RE@33958|Lactobacillaceae 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A CCPPCCOK_01905 334390.LAF_0436 2.13e-27 100.0 COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,3F82A@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C CCPPCCOK_01906 334390.LAF_0437 3.92e-80 241.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,3F5M8@33958|Lactobacillaceae 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B CCPPCCOK_01907 334390.LAF_0438 1.23e-119 342.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,3FC80@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP CCPPCCOK_01908 334390.LAF_0439 0.0 983.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,3F3R4@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N CCPPCCOK_01909 334390.LAF_0440 1.78e-213 590.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,3F40E@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt CCPPCCOK_01910 334390.LAF_0441 0.0 922.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,3F3TF@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N CCPPCCOK_01911 334390.LAF_0442 2.8e-87 257.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,3F6I6@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N CCPPCCOK_01912 334390.LAF_0443 8.07e-40 132.0 29PZU@1|root,30AY9@2|Bacteria,1U79C@1239|Firmicutes,4IH47@91061|Bacilli,3F95C@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1146) - - - - - - - - - - - - DUF1146 CCPPCCOK_01913 334390.LAF_0444 2.3e-276 758.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,3F795@33958|Lactobacillaceae 91061|Bacilli M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) - - - - - - - - - - - - EPSP_synthase CCPPCCOK_01914 334390.LAF_0445 9.42e-234 644.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F463@33958|Lactobacillaceae 91061|Bacilli D Cell shape determining protein MreB Mrl mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl CCPPCCOK_01915 334390.LAF_0447 7.67e-43 140.0 2BRKM@1|root,32KJX@2|Bacteria,1U6D6@1239|Firmicutes,4IG4Y@91061|Bacilli,3F7N5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2969) - - - - - - - - - - - - DUF2969 CCPPCCOK_01916 334390.LAF_0448 1.03e-282 773.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,3F4J4@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE CCPPCCOK_01918 334390.LAF_0450 3.83e-231 636.0 29SNM@1|root,30DU7@2|Bacteria,1V3Z9@1239|Firmicutes,4HHKX@91061|Bacilli,3F3VM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 CCPPCCOK_01919 334390.LAF_0451 5.85e-275 751.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,3F41Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N CCPPCCOK_01920 334390.LAF_0452 1.7e-195 543.0 COG1476@1|root,COG1476@2|Bacteria,1VMYH@1239|Firmicutes,4ISF0@91061|Bacilli,3F5QH@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,TPR_8 CCPPCCOK_01921 334390.LAF_0453 6.08e-107 308.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,3F68T@33958|Lactobacillaceae 91061|Bacilli T universal stress protein uspA - - - - - - - - - - - Usp CCPPCCOK_01923 334390.LAF_0455 1.3e-300 821.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3WF@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N CCPPCCOK_01924 334390.LAF_0456 1.97e-111 320.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli,3F64D@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 CCPPCCOK_01925 334390.LAF_0457 1.52e-98 285.0 COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,4HXCD@91061|Bacilli,3F679@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase,Glyoxalase_4 CCPPCCOK_01926 334390.LAF_0458 9.35e-173 482.0 COG2364@1|root,COG2364@2|Bacteria,1VSZX@1239|Firmicutes,4HTJ1@91061|Bacilli,3F4ZU@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - CCPPCCOK_01927 334390.LAF_0459 3.66e-191 531.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,3F3PH@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - DUF2179,YitT_membrane CCPPCCOK_01928 257314.LJ_1435 3.1e-16 73.6 2ETGE@1|root,33M09@2|Bacteria,1UPYE@1239|Firmicutes,4HS27@91061|Bacilli,3F8I9@33958|Lactobacillaceae 91061|Bacilli S YjcQ protein - - - - - - - - - - - - YjcQ CCPPCCOK_01930 334390.LAF_0487 5.1e-140 395.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,3F3P0@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 CCPPCCOK_01931 334390.LAF_0488 0.0 1056.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,3F47K@33958|Lactobacillaceae 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA CCPPCCOK_01932 334390.LAF_0489 1.43e-273 748.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,3F4CD@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 CCPPCCOK_01933 334390.LAF_0490 2.03e-292 798.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,3F3N0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI ## 1776 queries scanned ## Total time (seconds): 1.8422999382019043 ## Rate: 964.01 q/s