LOCUS       gnlProkkaHMCEBGJN_98   14878 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HMCEBGJN_98.
ACCESSION   gnlProkkaHMCEBGJN_98
VERSION     gnlProkkaHMCEBGJN_98
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 15:19:44
            Original ID  :: gnl|Prokka|HMCEBGJN_98
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14878
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14878
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2376:4878]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2377..4878
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     cand_cluster    1..14878
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14878
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     CDS             complement(237..488)
                     /locus_tag="ctg49_1"
                     /transl_table=11
                     /translation="MLEKYFTWLAEVLLIIVVGVGLVFITLHSLYYSYGMMIFGEHSAA
                     ATEMFWESEKIWSSIYTVAVIVIAVSTQIVRSFKRSKK"
     CDS             complement(491..1258)
                     /locus_tag="ctg49_2"
                     /transl_table=11
                     /translation="MKAIAVSDLSLILSFALVLVPVAISWKEKLGLTRDIFYSVGRAIV
                     QLVIVGYVLKFIMQVNNALLTLLMTLFIIFNAAWNANKRDPNPNRQLWQSIMALLIGTY
                     ITLGVLLLTQTVKLKPMQIIPITGMIAGNEMVAMGLCYKVLATGFHDQRQQVLEKIALG
                     ADVKTASMTILRRSIKTAMQPTIDSAKTVGLVNLPGMMSGLIFAGVDPVYAIKYQIMVT
                     FMLLSATGLGAVIAGYLSYRNYFNKRSQLREEQ"
     CDS             complement(1255..1893)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 203.4; E-value:
                     6.6e-62)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_3"
                     /transl_table=11
                     /translation="MALIELKQVSYRAGDQEILQDVSFAVEEGDYLTLTGPSGSGKSTT
                     LKLIAGLISPNKGEIFYKGQNLDSLDLVQYRRQVSYCFQQPTLFDETVKDNLALPFAIR
                     KQDFAEKRAQEALKQVDLPADYLDKKITTLSGGEKQRVALIRNLLFRPELLLLDEVTTG
                     LDEESKQIVYQLIARVHQEGTTIVQVTHDQEELAASKQLLHMEKGGVLK"
     CDS             complement(2196..2357)
                     /locus_tag="ctg49_4"
                     /transl_table=11
                     /translation="MNNVILDFEKMVERKAEQLSRKEITPASSLSILCTGHDVSSFGIG
                     SLLFKLFK"
     CDS             complement(2377..4878)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 75.2;
                     E-value: 9.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_5"
                     /sec_met_domain="micKC (E-value: 1.4e-133, bitscore: 437.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.2e-13, bitscore: 40.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEEQIKYLEAARNSGSLFYTRQKGEEEHFFTLKDRPDAAWLEKK
                     TANWHYVLYEPDELPVQGWKIHLSATVKQAQGMLDAVAPCLIKQKVSFKFQSSLEQYVE
                     SNSKYADRGESGKFITVYPRGEEEFACLLAELQKLTETFALGPYILSDQNWQESNVYFR
                     YGGFKPLYLANAAGERVPAIYDPAGNKVADQRLPYYQQADFVKDLPIFGKNTFPKQEAF
                     APLEEYQVKEALHFSNAGGVYLALHEGKKVVLKEGRQQAGLDANLKDGFARVENEAEIL
                     RQLADLTGVVNYLDDFTSWRHHFLVEEYIAGQSLEELLATEFPFVVGDLEKKARYKAKA
                     IKILEQLKELLKQIHDRGLAVGDLSLSNILVTEDGDVRLIDLENAGKATEKYVPGLTTV
                     GFVSRAAKTYAEADDFALARIAYYLFLPVIPVADLAPDIIAKQEKWIGGYFGQDLVQFL
                     RKIAGNMQASEPIFLKKPLAIPEKDLSRQTVDFFTDGLTRGILRHSRFDQVGLVPNLHE
                     KNADPMELLNLARGAAGILWAVGQNADLQAWVARNQGKIIKIAEESEATGLFNGLAGLA
                     SVLEKRDFPALAKQLRQILRQKVDLNMADNSLATGLTGIALALREEKPEVSEKIAEELA
                     GRWKQVDFANFADEDVGLLTGWGGVSWLFWQLGQKEVAEEIVSRILRDHAEEAETLTIS
                     DQSRGFERLLPYLENGNFGLALLMHKFMREDPAFKQRYQLPFDKLKKSCLTYCTYMETL
                     VSGYSGVLPLAKSLAGDGDYALLDYALAALNQYLVANNDEILAPGKYGYKLSLDFSTGS
                     AGLLTLLKDLRQRDEFSWLPL"
     CDS             complement(4885..6594)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 316.5; E-value:
                     5.9e-96)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_6"
                     /transl_table=11
                     /translation="MKLLKITPRLLWGILLSMIASLLNLYLPLLVRHFINLKQFAWSGL
                     SKKVLLLGGLILIGNLLVSSLSDYLISSEGDRQVRQLRLRLQKQVLRLPQKYFDQQISG
                     NLTSRIINDVNVLRSFLTETIPAVVTGSLTILGTMLITFSLDWKLTLLMLLVFPIDGLV
                     TVPLGKISEVIADQTQSSLAALTGVTSESIKQIKTVKLNKAEEDVFAKNAREINKLYRL
                     SLKGDRIAAMIGPLQSMLSFCLIMAVVLYGTLRVKSGSLSTGTLGAFMMYFFQIIGPIN
                     NVALFYSDRKQMLGATRKISEIINETAEETAGKEQLAVAPGSSLLRLDQVSFAYQDLPV
                     LEKVDLEARSGEKIALVGATGAGKTTLANVITRLYPVAAGRISLNGQASTDFSLEQWRG
                     FFSVVLQENTIISGSIRDNLTLGLNRKVTDQELWDALALVRLEEYAKKLPKGLDSLLGE
                     SGKQLSGGQRQRMQIARACLRDFKFLLLDEATSNLDADTEKIIMTALDRLKRTKNCGQI
                     TIAHRLATIANSDRIYFIKNKTVVASGSHEELLEKVPDYRRYVHEQQLKEKR"
     CDS             complement(6598..6765)
                     /locus_tag="ctg49_7"
                     /transl_table=11
                     /translation="MGNYILMIEKELSQAFKELEQPRSKHWNWRNAHSHISIMCPNSDS
                     HFSIFSIKIR"
     CDS             complement(6787..6954)
                     /locus_tag="ctg49_8"
                     /transl_table=11
                     /translation="MNTDTQNFQTENNPALKNLQGIATSLRAKKHRRKTRVSNSNISIL
                     CNHINFNILG"
     CDS             complement(6917..7090)
                     /locus_tag="ctg49_9"
                     /transl_table=11
                     /translation="MLKQCPAKCNASNAQGQKFNVQKLFFRGRLERHITGSIDLKGGNN
                     YEYRYSKFSNRK"
     CDS             7138..8442
                     /locus_tag="ctg49_10"
                     /transl_table=11
                     /translation="MINSLFNNLAFNPYLFSVLLAFTLAGVKRSDLLLYPLLLLPVLFG
                     YQYVLAAIIALQLISQLFARGQAKSLSRLFFYYLVLILYPILGELFGWIVQLLFYFFTH
                     HLLDHVAINLVCFLPEILICLLFCFLKKHFAINLEKIAADVKGNPQFLNLLVWIVWSFL
                     LVTHVIWSMIEVFSIAPLVELGLMTIVLLLITVLFFNLYQAIQKKQEIMATRIQKAEIQ
                     QIQEYSSRLEEANISLRKARHDYKNSLLALNGYLLTADVAGASKYLEELVADSNRLQEA
                     ANSMTLELANLQIKELKYLIIDKLQQAQDQGIKTKVEINKPIATLPVNIVSIIRCVGIF
                     FDNAIEACQSQADGQISVLLTKYSGNNYSLIVQNTISQPVNLAQVLKPRVTSKQNHDGL
                     GLDNVNEIVNSDPYLSLEIEQSVSEISFELVIQKG"
     CDS             8619..9230
                     /locus_tag="ctg49_11"
                     /transl_table=11
                     /translation="MNYLAFLDIDLKTSLDGIEVASRIKNIGILSQIVFVTADATALRL
                     TIERHVEPLDYITKDAAPLEIQHRIYETVDTAYKRYRLTMTSAKQTSYFTYSKIRNFVE
                     KIPLADLYYISIQPKKYKTLRVYAKNKVFDCLGTLKDYEKRYPSLVPADRQSLINLDAV
                     QNYDEKKGIAYFDQGIAHSVAVRRRRSVMLKLNATKNDLA"
     CDS             9248..9481
                     /locus_tag="ctg49_12"
                     /transl_table=11
                     /translation="MYADLCSQGYFPVKQVPLFFSQIVRDQNHCLFRLEQFVQDFPASC
                     LVDRAGPFINQEKLAVTNFRAGQHYFLLLPAR"
     CDS             complement(9971..10732)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 61.7; E-value: 9e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_13"
                     /transl_table=11
                     /translation="MTWEFSAIKDRHFQQFLLFAVLQLFLLLLGSLLDQVTDYFWELHL
                     EKYFHQIRQEVLAHAYAEAAGTKENLQNELTNDLEMLKEQYADSIGGIVHSAVLLALVA
                     GSLASFRWSLLLLVIAVSALQMYLPRVLDEPLQKATDKISASNRKYLQTLADWLNGIDT
                     LRRYAVGEKFLSIIHADARELESAYVKQQKADQELEYLNQAIYSLGNMLIFLLTAYFVA
                     RGQLEFCLIASVNDFSLYLFGSLMNIANYRG"
     CDS             11006..11710
                     /locus_tag="ctg49_14"
                     /transl_table=11
                     /translation="MEKFTGIPVSFQLVWLLRILLSAFCGGLIGFERATQRKSAGLHTH
                     VVVAIASTLFSIVSKYGFYDMLTFSNVSYDPSRIASLTVTGISFIGAGTIMVHKEQISG
                     LTTAAGLWATSAIGIAIGVGLYWVGIVAAVLLLLVQRFLREETVLNLLRKVSISLLIEA
                     RNTPHILETIQSELEKNEVHQLSIKIISVSDDHVLFSCDGEIASRIDENQIIMNLRKYP
                     DIKRITYSPGSK"
     CDS             complement(11821..12045)
                     /locus_tag="ctg49_15"
                     /transl_table=11
                     /translation="MKIETIKPIWLTLLLVLSFILPLLGWLPLVYLYSQRQDPAMQGME
                     KTLKLAAGVQVGYLVILAAIFYFFAPIHD"
     CDS             complement(12058..12213)
                     /locus_tag="ctg49_16"
                     /transl_table=11
                     /translation="MFNTIVNKKHWTYKTPRGMHLMGQATDKCAVGTQWAYVPISSDTR
                     TVGVQF"
     CDS             12882..14702
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 86.5; E-value:
                     4e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_17"
                     /transl_table=11
                     /translation="MSVKNNILLPLATSSDYNSDHAIKKLSEITRLLKIEDLLGKFPKD
                     LSGGEEQRVAIARALISQSKIILADEPTSSLDETNADNIYGFLSKLAHDFGKIVIVVSH
                     ESLPSKYADSILEIRNQSLLMVKDDTHSFTKDEEPIKKTNDLTLKQSFSYNSKLKNHIS
                     SLSCILSVVVVLLMLLSSYLPALPTILVNKQESSFSAVMDKNIFVVNDVAKVNSPQDLD
                     SYRAFSSKTTSKIKNAFLGAKVYPFINFTSYGITPTNVRTAVPKSYSIYLGNKQRTISN
                     DFSIQPIYPEDLNKKYFYEFGKPLKNSKNFVVSQDFLSQNGLSVKSVMNKVITLKAYVP
                     YLLYITETELPNDNTKSISIDGDVYKVVTIKAKISGVYKSNYPYHRSEQGNVFFMDYKA
                     MKDIQDKVISKSDIHKRVFKSFSQKAWAPSAYVLAMKNINQLKSAPKKLSSISKDIRTY
                     STLQNVDNVKQQLEQTKRATYKFTFFIVLLVFLVLYVIFNIIYKQRTYEFGILKCIGFS
                     NKDVFKIITAYSVKIGTLYALLGTIITVVSYFMLISKNTAIGMPIFFEALLRLVLLCYV
                     LTFLAVLPTFAKIAKIDPIDVITESRTADL"
ORIGIN
        1 tgatgaatac ttcttcctgc ggttaatgga actatcgcgg aaagcttcct aagtctctca
       61 gtcatttaca caagttttta tactgaacca aaaaattagc ggtaatactt ggtcagcaaa
      121 aggaggaata attcgacaat cgcattgctt cgattgcatc actttctgat aatcatcgcg
      181 cttcgattgt atcaagccat gcactcatcg ctactcataa cttaggcatc ctccagttac
      241 ttcttactcc ttttaaaaga tctgacgatt tgcgtgctta cagcaatgac tatcaccgcg
      301 acagtgtaaa tgctactcca aatcttttcg ctttcccaaa acatttcagt tgctgccgcg
      361 gaatgctcac caaaaatcat catgccataa ctatagtaga gcgaatggag agttatgaag
      421 accaagccta cgcctactac tatgattaac agtacttctg ccagccaggt aaaatatttt
      481 tctaacatcg ctactgctct tcccgcagct ggctccgctt gttgaagtag ttgcggtagg
      541 acaggtagcc cgcgatcacg gcgcccaggc cagtcgctga caaaagcatg aaagtgacca
      601 tgatctggta cttgattgca taaactggat ccacgccggc aaaaatcaac ccggacatca
      661 tccccggcag gttgaccagc cccaccgtct tagctgagtc gatcgtcggc tgcatggcag
      721 tcttgatgct ccgccgcagg atggtcatgc tggccgtctt cacgtcagcc ccgagggcga
      781 ttttttccaa aacctgctgg cgctggtcat ggaaacccgt ggctaaaacc ttatagcaca
      841 gacccatagc caccatctca ttgccggcga tcatccccgt aatcggaatg atctgcatcg
      901 gcttcagctt caccgtctga gtcagcagca atacgcccaa ggtgatgtaa gtcccgatca
      961 aaagggccat gattgactgc cagagctggc ggttcgggtt gggatcccgc ttattggcgt
     1021 tccaagccgc gttaaaaatg ataaataagg tcatcaagag ggtcaaaagg gcattgttga
     1081 cctgcatgat gaacttcaag acgtagccga caatgaccaa ctggacgata gcccggccca
     1141 cgctgtaaaa aatgtccctg gtcaagccca gcttttcctt ccaggaaatc gccacgggta
     1201 ccaggaccag ggcaaaagac aagattaatg acagatcgct gacagctatt gctttcattt
     1261 caaaactcct cctttttcca tgtgcaggag ctgcttggaa gcggccagct cctcttggtc
     1321 atgggtcacc tgcacgatcg tggttccctc ctggtgcacc cgggcgatca gctgatagac
     1381 gatttgcttg ctctcttcat ccagcccggt cgtcacttcg tccaacagga ggagctccgg
     1441 ccggaaaagc agattacgga tcaaagccac ccgctgcttc tccccgccag acagggtggt
     1501 aatcttttta tccaaatagt cagctggcaa atctacctgc ttcaaagctt cctgggcccg
     1561 cttttcagca aagtcctgct tgcggatggc aaaaggcagg gccaggttgt ccttaaccgt
     1621 ttcgtcgaac aaggttggct gctggaagca gtaggacacc tgccggcggt actggaccag
     1681 atccaggcta tcaagatttt gccccttgta aaaaatctcc cccttattag gtgagatcaa
     1741 gcccgcgatt agcttcaaag tcgtgctttt cccgctgccc gacggtccgg tcaaggtaag
     1801 gtagtccccc tcctccacgg caaaggagac gtcttgcagg atttcctggt cacctgcccg
     1861 gtaggacacc tgcttgagtt caatgagtgc cattttcttc ctcctgattt ctgcaatttt
     1921 tatactgcag ttacattata gtccaaaccg gatgaagcaa attttataaa agatcgaaga
     1981 attttgggca agaaaaaacc gccaccctgc aggtgacggt taaaatatgc tgactagagg
     2041 attcgaacct ccgacccctt cattactagt gaagtgctct gccaactgag ctaagtcagc
     2101 gactcttgtg ccttaacaca gttattaatt aaaccataaa aacgtgtcct tgacaagagc
     2161 tttcgcgaaa aaagttgatt tttttagtcg gacaactact taaacagttt gaaaagcaga
     2221 ctgccgatcc caaaactgct gacgtcatgc cccgtgcaaa gaatgctgag actgctggcc
     2281 ggcgtaatct ccttacggga caattgctca gcctttcttt caaccatttt ttcaaaatct
     2341 aaaattacat tgttcatgct tctccctcct tgcctgtcaa agcggcagcc agctgaactc
     2401 atcgcgctgc cgcaggtctt tcagcagggt caacaatccc gcgctcccgg ttgaaaagtc
     2461 caagctcagc ttgtagccgt attttccagg cgccaaaatt tcgtcattgt tagcgaccaa
     2521 atactggttc aaagcagcta aagcgtaatc cagcagcgca tagtcaccat caccagccag
     2581 actcttagcc agcggaagta ccccgctgta gcccgatacc agcgtctcca tgtaagtgca
     2641 ataagtcaaa caggactttt tcagcttatc gaacgggagc tgatatctct gcttaaaggc
     2701 cgggtcctcc ctcatgaatt tatgcatcag cagggccagg ccgaagttcc cgttttccaa
     2761 atatggaagc agcctttcaa agccgcgcga ttgatcgcta atggtcaaag tctctgcttc
     2821 ttcagcatgg tcccgcaaaa tccgcgaaac gatttcttcc gccacttctt tttgccctaa
     2881 ttgccaaaaa agccagctca cgccgcccca tcctgtcagc aggccaacat cctcatccgc
     2941 gaaattggca aaatccacct gtttccatct gccggccagc tcttccgcga ttttttcgct
     3001 tacttccggc ttctcttccc gcaaggccag ggcaatccca gtcaaacccg tggccagcga
     3061 attgtccgcc atattcagat caactttttg ccgcaggatt tgccgaagtt gcttggccaa
     3121 ggccggaaaa tcccgctttt ccaagacact tgccagtcca gccagaccgt tgaacaagcc
     3181 ggttgcctca gactcttccg caatcttgat tatcttccct tgatttcttg ctacccaggc
     3241 ctgcaagtcc gcattctggc caactgccca taaaatgccc gcggcaccgc gagctaagtt
     3301 cagcagttcc ataggatcag catttttctc atgcaaattt ggcactaatc ctacctggtc
     3361 aaagcgcgaa tgccgcaaga tccccctagt taagccatct gtaaaaaagt ccacggtctg
     3421 ccggctcaga tctttctcgg ggatagccag gggctttttc agaaaaatcg gttcggacgc
     3481 ctgcatgttt cctgcaattt tccgtaaaaa ctggaccagg tcctggccaa aatagccccc
     3541 aatccatttt tcctgcttgg caattatatc cggcgccaaa tcagcgactg gaatgaccgg
     3601 caggaaaaga tagtaggcaa tccgcgccaa ggcaaaatcg tcagcttccg cgtaagtctt
     3661 ggccgcccgc gaaacaaagc caaccgtcgt caaacccggg acatacttct ccgtagcctt
     3721 gcccgcgttt tcaaggtcaa tcaaacggac atccccgtct tctgtaacca ggatattgct
     3781 taaggacagg tcgccaacgg cgagaccgcg gtcgtgaatc tgctttagca gctccttcag
     3841 ctgctctaaa attttgatcg ccttggcctt atagcgggcc tttttttcaa gatccccaac
     3901 gacaaaggga aattccgtgg ccagaagctc ttccaggctt tgtccagcaa tatattcctc
     3961 taccaaaaag tggtgccgcc atgaggtaaa atcgtccaga taattcacca cgcctgtcag
     4021 gtccgccaac tgccgcaaga tttccgcttc attttcaact ctggcaaagc cgtccttcag
     4081 attggcatcc agtcctgcct gctggcgtcc ttcctttaaa actacttttt tcccctcatg
     4141 caaggccaaa tacaccccgc cagcattgct gaagtgcagg gcttctttga cttgatactc
     4201 ctctaaagga gcgaaagcct cctgctttgg aaaagtgttt ttaccaaaaa ttggcaggtc
     4261 tttgacaaaa tcggcttgct ggtaataagg cagccgctgg tctgctactt tgtttccagc
     4321 cgggtcatat attgccggaa cccgctcgcc agccgcgttg gccagataaa gcggcttaaa
     4381 accgccgtaa cggaaataaa cgttgctttc ctgccaattt tggtcgctca aaatatacgg
     4441 tcccagagca aaagtttccg ttagcttttg caattctgcc agcaggcaag caaattcctc
     4501 ctcgccgcgt gggtaaaccg tgataaactt cccgctttcg ccgcggtcag cgtacttgga
     4561 attcgattca acgtattgct ccaggctgct ttgaaacttg aaagaaactt tctgcttgat
     4621 caggcacggc gccaccgcat ccagcatccc ctgggcctgc ttaaccgtgg cactcaagtg
     4681 aatcttccag ccctggaccg gcaattcatc tggctcatac aggacgtaat gccaattagc
     4741 agtctttttc tccagccagg ccgcatccgg ccggtcttta agcgtaaaaa agtgctcttc
     4801 ctctcctttt tgccgggtgt aaaagaggct gccgctgttc ctggccgcct ccaaatactt
     4861 tatctgctcc tccagcatgc atgcctacct cttttccttg agctgctgtt catgaacata
     4921 gcggcgatag tcgggaactt tttccagcag ttcctcatga ctgccgctgg caacaactgt
     4981 tttattcttg atgaaataga tccggtcgct gttggcgatc gtggccagcc ggtgcgcgat
     5041 cgtgatctgg ccgcagttct tggtccgctt caaccggtcc aaggcggtca tgatgatttt
     5101 ttcagtatcc gcgtctaaat ttgacgttgc ttcatctaaa agcaaaaatt taaagtcgcg
     5161 caggcaggcc cgggcaatct gcatcctctg cctttgcccg cctgacagct gctttccgct
     5221 ctctcccagc agactgtcta accctttcgg caattttttc gcgtattcct ccaaacgcac
     5281 cagagccaaa gcatcccaaa gctcctggtc tgtcactttt ctgtttaagc ccagggtcaa
     5341 attatcacga atgctccccg agataatcgt gttttcctgc agcacgacgc tgaaaaagcc
     5401 ccgccattgc tctagggaaa aatccgtgct ggcctggccg tttaaactga tccggcccgc
     5461 ggcaactgga tacaagcggg tgatgacgtt ggccaaggtg gtcttcccag cccccgtcgc
     5521 cccaaccagg gcgatttttt caccactcct tgcttccaaa tcgacctttt ccaagactgg
     5581 cagatcctgg taggcaaaac tgacctggtc aagcctcagc agactgctgc ctggcgcgac
     5641 ggccagctgc tccttgccag ccgtttcttc agcggtttcg ttaatgattt cgctgatctt
     5701 gcgcgtggca cccagcattt gctttctgtc agaataaaaa agcgcgacat tgttgattgg
     5761 gccaataatt tgaaagaagt acatcataaa ggcccccagg gttccagtcg atagagagcc
     5821 gctttttacc ctcagtgtcc cataaagaac gacggccata atcagacaaa aagacagcat
     5881 tgactgcaag ggcccaatca tcgccgcgat ccggtcacct ttcagggaca ggcggtagag
     5941 cttgttgatc tccctggcat ttttggcaaa aacgtcctct tccgccttat tcaatttaac
     6001 agtcttgatc tgcttgatgc tctcactggt gaccccggtc agagcagcca agctgctttg
     6061 ggtttggtca gcgatcactt cgctgatttt tcctaaagga acggtcacta gtccgtcaat
     6121 gggaaagacc agcagcatga gcagagtcag cttccagtcc aaagagaagg tgataagcat
     6181 cgtgcccaag atagtcaagc tgccggtaac caccgccggg atcgtttcgg tcaaaaagct
     6241 tctcagcacg ttgacatcat tgatgatccg gctagtcaaa ttgccgctga tctgctggtc
     6301 aaaatatttc tgcggcaggc gcaggacctg cttttgaaga cgcaggcgca gctggcggac
     6361 ttggcggtcg ccttcactgc tgatcaagta gtcgcttagg ctgctgacca ggaggttgcc
     6421 gatcaggatc agcccgccca gcagcaagac ttttttagaa aggccggacc aggcgaactg
     6481 cttaaggttg ataaaatggc gaaccagcag gggcaaatac aagttcagca aactggcaat
     6541 catgctcagc aggatccccc acagcaagcg gggcgtgatc tttagcagct tcatggctta
     6601 acggatttta atcgaaaaga tcgaaaagtg gctgtcgctg tttgggcaca tgatgctgat
     6661 atggctatgg gcatttcgcc aattccaatg cttgcttctt ggctgctcca attccttgaa
     6721 ggcttggctc agttcttttt caatcatcaa aatgtaattt cccatgagat tgcctccctt
     6781 aaagaattag cccaaaatgt taaagttgat gtgattgcac agaatgctga tattgctgtt
     6841 gcttactctc gtttttcttc tatgcttttt agcccggaga cttgtagcaa ttccttgtaa
     6901 gttcttcaat gctggattat tttctgtttg aaaattttga gtatctgtat tcatagttat
     6961 ttcctccctt aagatctatg cttcctgtta tatgcctttc cagcctcccg cgaaaaaata
     7021 atttttgaac gttgaatttc tggccttgag cgttgctggc gttgcacttt gccgggcact
     7081 gctttaacat aaataacaac tattctgtag cacgtgtatt ttcaaggaaa taaaaaaatg
     7141 atcaacagcc tgttcaacaa tctagctttc aacccttacc ttttctcggt cctcctggcc
     7201 tttacccttg ccggtgtaaa acggtctgac ctgctcctct atcctctctt gttgctcccg
     7261 gtactctttg gctaccaata tgtcctggcg gccatcatcg ctttgcaatt aatctcccag
     7321 cttttcgcgc gcgggcaggc aaaaagctta agcaggctct ttttctacta tttagtcttg
     7381 atcctttacc ctatcctggg tgagctcttc ggctggatcg tccagctgct cttctacttt
     7441 tttactcacc acctgcttga tcacgtggcc attaatttag tttgtttcct tccggaaatc
     7501 ttgatctgcc tgctcttttg ctttttgaaa aagcactttg ccataaatct ggaaaaaatt
     7561 gccgctgacg tcaagggcaa cccccagttt ttaaacttgc tggtttggat cgtttggtcc
     7621 ttcctgctgg tcacccacgt gatttggtcc atgatcgagg tcttcagcat cgcccccttg
     7681 gtggaactgg gcttgatgac tatcgtgctt ttgctgatca cggtcctctt tttcaatctc
     7741 taccaggcga ttcaaaaaaa acaggaaatt atggccacac ggattcaaaa agcggaaatc
     7801 cagcagatcc aggagtattc ctcccgcttg gaagaggcaa atatctccct gcgcaaggcg
     7861 cggcatgatt acaaaaacag cctcctggcg ctaaacggct acctgctgac cgccgatgtc
     7921 gccggggcca gcaagtacct tgaagaactg gtcgctgaca gcaaccgcct gcaagaagcg
     7981 gccaactcaa tgactttgga actggccaat ttgcagatca aagaactgaa gtacttgatc
     8041 atcgacaagc tgcagcaggc ccaagaccaa ggcatcaaga ccaaggttga gatcaacaag
     8101 ccaattgcta ctctgcccgt aaatatcgta agcatcatcc gctgcgttgg catttttttt
     8161 gacaacgcga ttgaagcctg ccagtcacag gcagatgggc agatcagcgt tctgctgacc
     8221 aaatactcgg gcaataacta ttccctgatc gtgcaaaata cgatttccca gccagtcaat
     8281 cttgcccaag ttctgaagcc aagggtaacg agcaagcaga atcatgatgg actggggctt
     8341 gataacgtca acgaaatcgt taacagcgac ccatatttgt ccttggaaat tgagcaaagc
     8401 gtcagcgaaa tttcatttga attagttatt cagaagggat agaaaaaatg ctagccatca
     8461 tcattttgga agacaatact gctgaacgtg aaatcattca gcaaatgatt gaaaacagaa
     8521 ttcagatcaa cgagacgcct gctgcttatg atgcccgtgt cgtcttgagt accggcgatc
     8581 ctcacagcgt attggcttat atcgcggagc atcaagattt gaactacctg gcttttttgg
     8641 atattgacct gaagaccagt ctggacggca ttgaagtcgc cagccggatc aaaaacatcg
     8701 gcattttgag ccaaattgtc tttgtcaccg ccgacgcgac ggccttacgg ctaaccattg
     8761 agcggcacgt tgagccattg gactatatca ccaaagacgc ggctccctta gaaatccagc
     8821 acagaatcta tgaaacagtt gataccgcgt ataagcgcta ccggctgacc atgacttcgg
     8881 caaagcagac aagctatttt acctacagca agatccgcaa ttttgttgag aagattccac
     8941 ttgctgacct ctattacatc agcattcagc cgaagaagta caagacttta cgcgtttacg
     9001 ccaaaaacaa ggtcttcgat tgcctgggca ccctcaagga ttatgaaaaa aggtatccta
     9061 gcttggtccc agctgaccgg caaagcttga taaacctgga tgcagtacaa aattacgacg
     9121 aaaaaaaggg catcgcctat tttgatcaag gcattgccca ttccgttgcc gtccgtcgcc
     9181 ggcggtctgt catgttgaaa ctgaatgcaa caaaaaatga ccttgcttaa acaaggtcat
     9241 tttctttatg tatgctgatc tatgctcgca aggctacttc ccggtcaaac aggtcccgct
     9301 cttctttagt cagattgtgc gcgatcaaaa ccactgtctg tttagactgg agcaatttgt
     9361 ccaggatttt ccggccagct gcttggtcga tcgcgctggt cccttcatca accaagagaa
     9421 gctggctgtc acgaacttcc gcgcgggcca acactacttt ctgcttctgc ccgccagata
     9481 aattgtcccc tgccaagtca accggcgttt ccaggccttg aggccaacta tcaactgcct
     9541 cagacagctg ggcgtcggcc gcgctggcct tcgcctttga ctcaagctct ggatcaaaca
     9601 tggtgatatt gttcatgacg ctgcttggca ataagaccgc ctgctgaggc agatagccga
     9661 ttttggtccg gtcaggcttc accttttttc cagcttggtc aaaaaagctg atctgtcctc
     9721 cgctggccgc tgcttcccct accaggagct taaacagagt cgacttgcca gtcccgttgg
     9781 ccccggtcaa gagtactttt tcccccggct taacttggat atctggatac ttgatttcgt
     9841 gtccattggc aaaagtcagc cgcagatcct ttacagagaa ggcagctggc gctgtccccc
     9901 cttcttccgc ttgagccagt ggctaccgca agtccagaat cttttcccgc aagccgcggc
     9961 tggcaaccag ctacccccgg taattggcaa tgttcatcag agagccaaac aagtacaagc
    10021 tgaagtcatt taccgaggca atcaagcaga attcgagctg cccgcgcgct acaaaataag
    10081 cagtcagcag gaaaatcagc atgttcccca aagaataaat agcttgatta aggtattcca
    10141 gttcctggtc agctttctgc tgctttacat aagcagactc taactcgcgg gcatcagcat
    10201 gaataatgct taggaatttt tccccgaccg cgtagcggcg caaagtatca atgccattga
    10261 gccaatcggc cagagtctgc agatatttcc ggttgctggc cgaaattttg tcagtagctt
    10321 tttgcagtgg ctcatcaagt acgcgtggca agtacatctg caaggcgctt acggcaataa
    10381 ccagtaagag caggctccag cggaaagagg ccaaagaacc ggcaaccaag gccagcaaga
    10441 ctgccgagtg aacgatgccg ccaatagaat cagcgtactg ttccttcagc atttccaagt
    10501 cattagtcaa ttcattttga agattttcct ttgtcccagc cgcttcagca taagcgtggg
    10561 caagaacctc ctgccggatc tggtgaaaat acttttcaag gtgaagttcc caaaaataat
    10621 cggtcacttg atccagcagg ctgccaagca agagcaagaa aagctgcaga accgcaaaca
    10681 gcagaaattg ctgaaaatgc cggtctttta tcgcgctgaa ctcccaggtc aagacaaaaa
    10741 aactttattt atctttgcaa aacgctgata aataaagttt aatcgtaaac aagaatctgt
    10801 ataatgctga ctagaggatt cgaacctccg accccttcat tactagtgaa gtgctctgcc
    10861 aactgagcta agtcagcaac tcttgtgcct taacacagtt attaatttaa tcattaattg
    10921 cagacttttg caagtctttt tggaaatttt ttattttttc ggcttatttg cgccgaaaga
    10981 actaaaatca gcaaggagga aaaatatgga aaaatttacc ggcatacctg tcagctttca
    11041 actggtctgg cttctgcgga tcctgctatc cgccttttgc ggcggcctga ttggctttga
    11101 gcgggcaaca cagagaaaga gcgcgggcct gcatactcac gtcgtggtag ccattgcctc
    11161 caccctgttt tctatcgtct ccaagtatgg gttctacgac atgctcactt tcagcaacgt
    11221 ttcttacgat ccatcgcgaa tcgcttcttt gacggtcacg ggaatctcct ttatcggtgc
    11281 cgggaccatc atggtccata aagagcagat ttccggattg acgaccgccg cgggactctg
    11341 ggccacttca gccatcggaa tcgcgattgg ggtcggcctt tactgggttg gaatcgtggc
    11401 cgccgtcctg ctcctgctcg tgcagcgctt tttgcgggaa gaaacggtcc tcaacctgct
    11461 ccgcaaggtc agcatcagcc tcttgatcga agccagaaac acgccccata tcctggaaac
    11521 cattcaaagc gaactggaaa aaaacgaggt ccaccagctc agcatcaaga tcatcagcgt
    11581 ctctgacgac catgtccttt tcagctgcga tggcgaaatc gccagccgga tcgatgaaaa
    11641 ccagatcatc atgaacctgc gcaaataccc ggatatcaag cgcatcactt actcgcccgg
    11701 cagcaagtag ccctcacgtg aaaaaaactg acagagtgat aaaatatttc tctataaaga
    11761 cttagctgac aaggaggcat taacaagatc ttgtactaaa aaaattgaaa tcatgtgttt
    11821 ttaatcgtga atcggggcaa agaagtagaa gattgccgcc aaaatcacca agtaccctac
    11881 ttgcacgcca gccgcgagct taagcgtctt ttccatcccc tgcatggccg gatcctgccg
    11941 ttggctgtac aagtacacca gtggcaacca gcccaacaac ggcaagatga agcttaaaac
    12001 caaaagcaga gtcagccaaa tcggcttaat cgtttcgatt ttcattccgc tcactcctta
    12061 gaattggacg ccgacagttc tagtatcgct agaaatagga acgtatgccc attgcgtccc
    12121 aactgcacac ttgtcagtag cctgccccat caagtgcatc ccgcgagggg tcttatacgt
    12181 ccagtgcttc ttattaacaa tcgtgttaaa cattgcacta ccggatgtga tccaagctga
    12241 agtaaccttc ccactgtttg gatatgaata tccttttccg tgcaaagtga accaaccggt
    12301 cgtaatattt gctcttgact tccacgtaca tgtcgcttgt ctagaaacaa atgctgcatc
    12361 agctttctgt tcatttaagt ttgcaaagac tgcaaagact gacatagccg cggctaaact
    12421 aattagccct tttgcttttc ttctcataaa atacactcct aaaatcatca aataaagaga
    12481 gataacttac tatacacttt gctttcgctt agtgtacaat gtcattatat tactctgccg
    12541 ataaattgtt aagataaata ttgaaagtaa atttgtgtat aaaaggatat attacaatgg
    12601 atctattaaa aattgaggga ctttccgtta aatatagcga aaaaactatt ttatcaaaaa
    12661 ttagtttttc atttttgcct ggcaattttt atttaattaa gggaccttca gggatcggta
    12721 aaactagctt aataaattgc cttggattat taaaaaagcc gtctagcggt tctgtcttct
    12781 ggggagagaa gaatttatgg gaattgtctg ataacgaccg tgccgatttt agacactcat
    12841 atattagttt tgttttccaa aaaaataatc tagtggaaaa tatgtctgtt aagaacaaca
    12901 tcttgcttcc attagcaacg tcttctgact acaatagtga tcatgctata aaaaaattat
    12961 ctgaaattac gcgattgctc aagattgaag acttgctagg caaatttcca aaagatttgt
    13021 cagggggaga ggaacaaaga gttgctatcg cccgggctct tatctctcaa tcaaaaataa
    13081 tcttagctga cgaaccaaca agttcactag acgaaacaaa tgctgacaat atatacggct
    13141 ttttgtccaa gctagcacat gattttggca aaattgtcat tgtcgtttca cacgaaagcc
    13201 tgccttccaa atacgcggac agtatattag aaataagaaa ccaatccttg cttatggtaa
    13261 aagatgatac ccattccttt accaaagatg aagagccaat aaaaaagaca aacgacttaa
    13321 cgcttaaaca atcttttagt tataattcaa agctcaagaa ccatatatct tctctttcct
    13381 gtattctatc tgtcgttgtc gtactcctca tgttactttc ttcgtatctg ccagcactgc
    13441 caacgattct tgtaaacaag caggaaagtt cattctcagc tgttatggat aaaaacatct
    13501 ttgtggttaa cgatgttgcg aaagttaaca gtccacaaga ccttgattca tatcgcgcgt
    13561 ttagcagcaa gactaccagt aaaatcaaga atgccttctt aggcgcaaaa gtatatccct
    13621 ttatcaattt tacttcttac ggaatcaccc caacaaatgt gcgaactgca gtcccaaaaa
    13681 gctattcgat ctatttagga aacaagcagc ggacaatcag taacgatttt tccattcagc
    13741 ctatctatcc tgaagatctc aataaaaaat atttctacga gtttggtaag cctttaaaaa
    13801 attccaagaa ttttgtcgta tcacaagatt ttctatcaca aaatggactt tcagtaaaaa
    13861 gcgtgatgaa caaagtcata acgttaaagg cctacgttcc ctacttgctg tatataactg
    13921 aaactgagct tcctaacgat aatacaaaga gcatatctat tgatggcgat gtctataaag
    13981 tcgtaaccat taaagctaag atttccggag tatataagag caactaccct tatcaccgtt
    14041 ctgagcaggg gaatgtattt ttcatggact acaaagcgat gaaagacatt caagataagg
    14101 tgatttccaa gtctgatatt cataagcgag tgtttaagtc tttcagtcaa aaggcttggg
    14161 ctccgagtgc ttatgttctg gccatgaaaa atatcaatca actgaaaagc gcacctaaaa
    14221 agctgtcctc tatttctaaa gatatccgta catactctac gttgcaaaac gtagataatg
    14281 tcaaacagca gcttgaacaa actaagcgcg cgacatacaa gtttacattt ttcattgttc
    14341 tgcttgtttt tctggttctc tacgttatct ttaatattat ctacaagcag cggacttatg
    14401 aattcgggat tcttaagtgc atcggcttct caaacaaaga tgtctttaag atcatcacag
    14461 cgtactctgt aaagatcggc actctatatg cccttctcgg tacgatcatc acagtagtaa
    14521 gctacttcat gttaatctca aagaatacgg ccatcggtat gcctatattc tttgaggcac
    14581 tgttgagact tgttctgctt tgctatgtac ttactttctt agcggttttg cctacttttg
    14641 ccaaaatagc aaaaattgat ccaattgatg ttattaccga aagcagaact gcagacctat
    14701 aaaacaatta ttttacggca ctcattagag tgccgtattt ttataaaaag ccttccccgc
    14761 cccgcttttt gcgcaataat gtacaatgtt agctaaggag gtttttgcca tggcatcaac
    14821 attagactat ctgcgctggc gaggcgatct gccttttcaa gcttgccctt tcaacagc
//
