LOCUS       c00149_gnlPro..        14749 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PAKDJCJJ_252.
ACCESSION   c00149_gnlPro..
VERSION     c00149_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 16:01:24
            Original ID  :: gnl|Prokka|PAKDJCJJ_252
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14749
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14749
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:4749]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..4749
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..14749
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14749
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             3..95
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg149_1"
                     /sec_met_domain="Amidinotransf (E-value: 6.6e-11, bitscore:
                     33.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKVIDVLSSELSRGRGGPRCMSMPLVREDL"
     CDS             137..1168
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg149_2"
                     /sec_met_domain="OTCace (E-value: 4.7e-53, bitscore: 171.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 8.4e-44, bitscore:
                     140.9, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKDFRENVFQGRSVLAEKDFTAEELEYLIDFGLHLKTLKKNHIP
                     HRYLEGKNIALLFEKSSTRTRSAFTTASIDLGAHPEYLGQNDIQLGKKESTSDTAKVLG
                     SMFDGIEFRGFKQSDAEILARDSGVPVWNGLTDEWHPTQMLADFMTVKENFGKLKGLTL
                     TFMGDGRNNVANSLLVTGAILGVNIHIVAPKELFPTKETQDLAKGFAEKSGAKLLVTDD
                     LAEGMRGSNVVYTDVWVSMGESNWEERVNLLKPYQVNMEALKMTGTPDDELIFMHCLPA
                     FHNVETQYGQDIKEKYGITEMEVTDEVFTSKYARQFEEAENRMHSIKAMMAATLGNLFI
                     PRA"
     CDS             1245..2657
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg149_3"
                     /sec_met_domain="AA_permease_2 (E-value: 4.4e-59, bitscore:
                     192.0, seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDENKGLSMGALTAAVVTSSIGSGVFTLTSSLAGGAAAGPVLLAW
                     LVVGFGILMLALSLNNLLQKNPEAEGVQAYAQAGFGNFAGFVSGWGYWLSAWLGNVAFA
                     TVLMSSLGYFFPLFKGGQNVPSVILASVVSWGLTYIVNRGVESAAAMNTIITICKLIPL
                     FTFIVVGIFVFKGGMFTAHFWSNVSSGVAGGANIWTQFKSCLMIMMWVFVGVEGASMLS
                     SRAKSKSEAGRATIIGIICLLIIYVLASVLPYGYLSQDALAKINQPAMLYIFQDMVGTW
                     GGAFIGVGLIIAILGSWLSWTMLPADTTMLMAEEKLLPAYFGKKNKNGAPTFSLVLTAA
                     LIQIFLLVLLFSEEAYNFALSLCTAAIVVCYIFVGAYQVKFSYQNKDMKQFWIGFFALL
                     FQVVAITLAGLHFLMLVCIGYLPGIYFYYRAKKDYSLDGGKLTKMEILYSIAIVAFAII
                     SIVMVAMGAIQI"
     CDS             2668..3777
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg149_4"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.8e-46, bitscore:
                     150.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIDEFGVEGWLNVHEREAKYDLAQSTITSFSMNELVSLTKADQT
                     YSELDQQKMNYGWIEGSPTFKQEVSKLYDHVDPDNVLQTNGATGANMLALYSLIEPGDH
                     VISVYPSYQQLYDIPRSLGADVSFWKLREEDNWYPDIDELKRLVRPTTKMICINNANNP
                     TGTILDRNFMKQVVAVAKSVDAYVLVDEVYLPFDDSVDFAPIIDLYDKGISTNSLSKTY
                     SMPGIRVGWTATNAELAERFRKYRDYTMICAGVFSDQAACLVLQNREKVLARNRQIVLD
                     NLQIFKDWVERTPKVSCVFPNGVSTSFIKMETNESSENFCRHLLADTGVLLVPGEAFDV
                     PGHARLGYCAPTETLEKGLEILGQYLEEH"
     CDS             3805..4749
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg149_5"
                     /sec_met_domain="AA_kinase (E-value: 1.6e-34, bitscore:
                     111.2, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKRRIVVALGGNAILSKDASAEAQQQALRDTAKYLVQFIKQGDD
                     LIVSHGNGPQVGNLLLQQAAGSTDKNPAMPLDTAVAMTQGSIGYWMQNALDEEITKAGL
                     DKDVTTMVTQVEVDPDDQAFTNPSKPIGPFYTEAEIKDIKAAHPEYTYVEDAGRGYRRV
                     VPSPRPTGVKEYKVVNALVDAGIVPISVGGGGVPVVREGDRLVGREAVIDKDFASEKLA
                     ELVHADLLIILTAVDNIYINFNKPDQKKLETVSVAELQEYIDQDQFAKGSMLPKVQAAI
                     NFVNNSEGGKAVVTSLENVGNFLKNGDGTIITK"
     CDS             4826..5506
                     /locus_tag="ctg149_6"
                     /transl_table=11
                     /translation="VIKKSDYPRYIQMLKRRPEFSGFTPDEFNQLEQQMRIKEYPKGQL
                     LFDQADTRSRFYFVISGLLRSERIDETGDFSFYSFIAENKGFPYRGLFHDHEYAYAVNT
                     MTPAVVVSFPMANFENLLTRNSEMMKRVIVEMGQIINENEDQLQQMVTSSASDRVRNAL
                     KILGHKLGNRLKDDRWFVPYAITLIELAKMAGTTRETASQVVQRLEAEGQIIYEHKHFT
                     IFIK"
     CDS             5594..6310
                     /locus_tag="ctg149_7"
                     /transl_table=11
                     /translation="MTMKQVVIDKNFWTTFPDAQINLMWISDFDNHDTDENKAERQQLL
                     HDATVASKHFTKIDPFRDNPVVAEWRDAYQQFKKRKGARSSIEALLKRASQGHEFIPIE
                     PLVDVYNSISLRYGVPLGIEDRDKIAGDLHLGLAQGGESFFPLGAEADDPAREGEMIYY
                     DDEGAVCRSLNWREAQRTMLTEETTNGIVVMELMNADQAARATAAMAELQKLIQHYFGI
                     EPGEIKTLTKEHPTVD"
     CDS             complement(6400..6792)
                     /locus_tag="ctg149_8"
                     /transl_table=11
                     /translation="MKLKIASILLVFGFSFGMVTDVTTNLLPQTTTTAQASTKLTASQK
                     KQIVKINASLSKKQMAAKNWIAYHESSYNYRAVNGNCYGRYQLLKSYLHGNLSPVNQEK
                     VANSYVKGRYGSWTKAKKYWQSHHWY"
     CDS             7023..7598
                     /locus_tag="ctg149_9"
                     /transl_table=11
                     /translation="MYELLVLGSLLSRDMSGYKLCQVLGNALVPRRKISNGVMYPLLNK
                     LAAAGDITFVTDTTDARGKKVAHLTATGRAHLHDMLVTPVTTDAKRESLYRFKFKGMAT
                     EPVAVQSQILNEYKEALLTDLQIYQQVYLHLKEKLATASMDRHASLDWSIRTLELQIAE
                     SETKIKWSNRQLQDLRLTDAHGGKTNYD"
     CDS             7567..7965
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg149_10"
                     /sec_met_domain="MFS_1 (E-value: 1e-16, bitscore: 52.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLMEVKRIMTKRYRQWIGLVALSLGVFMALLDVTIVNVALPTMVR
                     DFNESFNNVQWVLNAYSLVLGVTLLIVSKIGDMYGLKKIFVLSLGLFVLASAINGLAPS
                     LLVLDIGRGVQAVGGAGMNCTGNGLGCG"
     CDS             7946..9133
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 100.5; E-value: 3.1e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg149_11"
                     /sec_met_domain="MFS_1 (E-value: 2.5e-31, bitscore: 100.5,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALVAVSFKGGKRGVALGILGSVIGLSSASGPLVGGYLVAQFGWR
                     SIFYVNIPIGIVAIILTLIYVDEVPDISRSQKIDFAGMFLSAASLFTLIYGLILKESHP
                     HWGWLSGQMIGWFGAAILFFIVFIVVESRISQPMINLTMFKNPHFVGTVMVALALGAGI
                     YSYNTYLTALMQNYMGYSALGAGVRQLTISIWSLLLGPITGYLGNRYSKKWMISGSLFL
                     GGIGFLLLANAMTVKVSFMALWPGMVLMGITNGLVNPLLNSAGMEGVAVREMGMASGLI
                     NVFRQIGVTLGIVCLGLVQNKVYETYLTQHFSRVNMPHAAAKAIHQALVNAGPFSGHSI
                     AFSSRLSQTPFGHVVQQIVWQAYANGTRAVSLAAAGIVIAGGLCAAVLMRNRKAH"
     CDS             9280..10902
                     /locus_tag="ctg149_12"
                     /transl_table=11
                     /translation="VCHQLGITPFLLLAEIIKVGYAVTDTLSNGTYASTLLKLVLNLKQ
                     FGWYRGKIFRPCDRDDGSFFGVAVIHGRRNKVMVDVLVKNLFSDRHFAEDEVVTLHGWV
                     KTVRGSKRVGFIELSDGSTIKHAQIVMQSDLENYAEMTKLPLSSTIKVVGTVVYTPDAK
                     QPLEIHAQEVVLEGASDNDYPLQKKKHSYEYLRTMAHLRPRTNTFYAVFRIRSLAAFAI
                     HQYLQEHGFTYVNTPIITSSDSEGAGEMFRVTTLDMNNLPKTEDGRVDDHEDFFKKETN
                     LTVSGQLPVEAFALALRNVYTFGPAFRAENSHTSRHASEFWMIEPEMAFADLQDTINEA
                     EGLLKYVVQYLLDHAQDELAFLDSAVDDDLLNRLHQTCDEKFAQITYTQAIEELKKAPV
                     DFDVPVSWGLDLQAEHERYLCEQVYKRPTFLTDYPKEIKAFYMRDNEDGKTVAAADLLV
                     PRIGELIGGSQREERQAQLAQKIKDYNLPPEEYQWYLDLRKYGETPHSGYGIGFERLLM
                     YVTGMENIRDVIPYPRTPGNAEF"
     CDS             complement(10997..11911)
                     /locus_tag="ctg149_13"
                     /transl_table=11
                     /translation="MKFMTHVSRDYLIGFALVLLMVAGAMFLHDQEIILPEIAALTAGM
                     WIYHNPRWLHQPYKIFLAPSGTAVIGFLINQLPVNYPIKISLTLVGILVLLRELRSPLA
                     PAFATGLLPIIVNATHWSFIGAIFLFTLILMIGVLRQGHYRRAIASDPIHFQHILGFAA
                     VAIVWIIGVCLAGQPQMAGIPPVLVVFFEVLQRPTYSGKLALKQIAALSGAATIGVVGH
                     LLVTSWLLATLISLPLVLLLLALLNLKLPAAYAFPLLALVLPPTMFIHLPIAATLAASF
                     FLGTVLVYRKITAAMTTSITEEN"
     CDS             12166..12423
                     /locus_tag="ctg149_14"
                     /transl_table=11
                     /translation="MLGWLWSLIVGAIIGAVAGAITNRGGSMGWIANILAGLIGSWLGQ
                     ALLGSWGPTLAGMALVPSILGAIILILIVSAIFGVRGKAK"
     CDS             12436..12981
                     /locus_tag="ctg149_15"
                     /transl_table=11
                     /translation="MRRGNKGLLTILGLILLALGIFQLGWWLPIPGLSAWSLEMSYTQM
                     AWLKYVLAGAVIITGIVGLGLVVIGIFKPIREKQWQFTNRLGMLEVPQAALEKALRHQL
                     VEQVGLVDPRVTVKLLRHRRARVTAIAQVSATDQIDPLAQQASQVIDAYLQQQLDLTAV
                     KPVVRLSPVDRQRHVSVV"
     CDS             12995..13177
                     /locus_tag="ctg149_16"
                     /transl_table=11
                     /translation="MSNGAYGALWGLVLGLVWVFQSFPAMLLVAVFGLVGWGIGRFVRL
                     DLSALGKRIEQLLSR"
     CDS             13194..13613
                     /locus_tag="ctg149_17"
                     /transl_table=11
                     /translation="MTTEKPTLTTKLTFEDDVIKKIAGLASRNIDGVLALEGGMISNLT
                     NRFRNDSDPTQGVQAQVGEQQAALDMTITVEYGKDMRQIFNQLCQRVQQDIERFTGLEV
                     VDIKVHINDVMSKQEWQEQAAGKPNSTVDTDDKVK"
     CDS             13625..14035
                     /locus_tag="ctg149_18"
                     /transl_table=11
                     /translation="MDKQPEATQTIIFDDMVLEKIAGKTASEVDGVLSLQGNLIDNLSD
                     RLTESDRPQSGVDIELDDQQKTVAIELDAILEYGKRAEEILTKVTSKITSAVTTMTGYR
                     VTEVKLRVKDMLTKDEWQQRQQSSRSKKKKDD"
     CDS             complement(14149..14511)
                     /locus_tag="ctg149_19"
                     /transl_table=11
                     /translation="MDKQPLIAPRFLNEFDATMQLIQGKWKIMILYELDEDDHCRFADL
                     QHHIQAVSHKTLTSQLRELQADGLITRHDFHTAQPHVEYALTPMGQSLIPILDAICTWG
                     TIHIDPALMARTLCDE"
ORIGIN
        1 gtctaaaagt gattgatgtc ttatcaagtg aattgtcacg gggccgtggc ggtcctcgtt
       61 gcatgagtat gccattagtt cgagaagacc tttaatttta aaaactaaaa cacaagagaa
      121 taggagatca tgaattatga ctaaggattt tcgggaaaat gtattccaag gacggagtgt
      181 tcttgctgaa aaggacttta ctgctgaaga attggaatac ctgatcgatt ttgggttaca
      241 tttgaagacg ttgaagaaga accatattcc tcaccgttac cttgaaggta agaacattgc
      301 cttgctgttt gaaaagtcct caactcggac ccgttctgca ttcacgacgg catccattga
      361 tttaggtgct caccctgaat acttgggtca aaacgacatt caattaggca agaaggaatc
      421 cacttctgat actgccaagg ttttaggtag tatgtttgat gggattgaat tccggggctt
      481 caagcaatct gatgctgaaa tccttgctcg cgattctggt gttcctgttt ggaatggttt
      541 aactgatgaa tggcacccaa cacaaatgct ggctgacttc atgacggtca aagaaaactt
      601 tggcaagctg aagggcttga cgttaacctt tatgggtgat ggccggaaca acgtggctaa
      661 ctcactattg gttactggtg cgatcttggg tgtgaacatc cacatcgttg cgcctaagga
      721 attgttccct acgaaagaaa ctcaagacct ggctaagggc tttgctgaaa agtcaggtgc
      781 taaattactc gttaccgatg acttagctga aggtatgcgt ggatctaacg tggtctacac
      841 cgacgtttgg gtatctatgg gtgaaagcaa ctgggaagaa cgtgttaact tattgaagcc
      901 ttaccaagtt aatatggaag ccttgaagat gacgggtacg cctgatgatg aattgatttt
      961 catgcactgc ttacctgcct tccataacgt tgaaacccaa tacggccaag acattaagga
     1021 aaagtatggc attactgaaa tggaagttac tgacgaagtc ttcaccagca agtatgctcg
     1081 tcaatttgaa gaagcagaaa accggatgca ctcaatcaag gcaatgatgg ctgctacctt
     1141 aggtaactta ttcattccac gagcttaatc tgaagggtcg aagagggtta atcgtgctga
     1201 ttaaccctct tttattttaa attcgataga gagtgtgaga aattatggat gaaaataaag
     1261 gcttatcaat gggcgcgcta accgccgccg ttgttaccag ttcaattggt tctggggtct
     1321 tcacactgac cagttcatta gccggcgggg ctgctgccgg gccagtgctg ttggcctggt
     1381 tagtcgttgg tttcgggatc ttaatgttag cgttatcttt aaataattta cttcaaaaga
     1441 atccggaagc tgaaggtgtt caggcgtatg cacaggctgg atttggtaat tttgctggat
     1501 tcgtcagtgg ctggggatat tggttgagtg cttggttagg taacgtggcc tttgcaacag
     1561 ttctgatgag ttcactgggt tatttcttcc cgctgttcaa aggtggtcaa aatgtcccat
     1621 cagttatctt agccagtgta gtttcgtggg gactaaccta tatcgttaac cgcggggttg
     1681 aatctgcggc cgcgatgaat acgattatca cgatttgcaa gttaattcca ctgtttacct
     1741 tcattgttgt tggtatcttt gtcttcaaag gtggtatgtt caccgctcac ttctggtcaa
     1801 atgtatcttc cggtgtagca ggtggcgcca atatttggac acaattcaag tcttgcttaa
     1861 tgattatgat gtgggtcttc gttggggttg aaggggccag catgttatct tctcgggcca
     1921 agagtaagag tgaagctggt cgggccacaa tcattgggat catttgccta ctgattattt
     1981 atgtattagc ttcagttttg ccatacggtt acttaagtca agacgctttg gctaagatca
     2041 accagccagc aatgttatat attttccaag acatggttgg tacttggggt ggggccttca
     2101 ttggtgtcgg cctgatcatt gctatccttg ggtcatggtt atcttggacg atgctccctg
     2161 ctgatacaac gatgttaatg gcagaagaaa aactcttacc agcttacttt ggcaagaaga
     2221 ataaaaatgg tgcgccaacc ttttctctag tcttgacggc ggctttgatc caaattttcc
     2281 tgttagttct tctattctcc gaagaagctt ataactttgc attatccttg tgtacggctg
     2341 ctattgtggt ttgctacatc ttcgttggag cctatcaagt gaagttctct tatcagaaca
     2401 aagacatgaa gcaattttgg attggcttct tcgcactctt gttccaggtt gttgcgatta
     2461 ccttagccgg tttacacttc ttaatgttgg tatgtatcgg ttacttacca gggatttact
     2521 tctattatcg cgctaagaaa gattatagtc tcgatggtgg taagttgact aaaatggaaa
     2581 ttttgtattc gattgccatt gtggcctttg ccattattag tattgtaatg gtggcgatgg
     2641 gtgctatcca gatttaggag gtaaaccatg gaaattgatg aatttggggt cgaaggctgg
     2701 cttaacgttc atgagcgaga agccaagtat gatttagctc agagtaccat cacatcgttt
     2761 tcaatgaacg aattagtttc attaactaaa gctgatcaga cctattctga actggatcaa
     2821 caaaagatga actacggttg gattgaggga tcaccaacct ttaagcaaga agttagtaag
     2881 ctctatgacc atgtagatcc ggataatgtg ttacaaacca atggggccac gggggctaat
     2941 atgttagcac tttactcatt gattgaaccg ggagatcatg tcattagcgt ttatccgagt
     3001 tatcaacagc tctatgatat tccgcgatcc ttgggagcag atgtcagctt ctggaagcta
     3061 cgagaagaag acaattggta tccggatatt gatgaactaa aacgattggt tcgaccgaca
     3121 actaaaatga tttgtatcaa taatgcaaat aacccaacgg gaacaatctt agaccggaac
     3181 tttatgaaac aagtcgttgc ggttgctaaa tcggttgatg cttatgtttt agtggacgag
     3241 gtttacttac catttgatga tagcgttgat tttgcaccaa ttatcgattt gtatgataaa
     3301 ggaatttcga cgaattcatt atcaaagacc tattcaatgc cggggattcg agttggttgg
     3361 acggcaacta atgctgaatt agctgaacgt ttccgaaagt atcgggatta cacgatgatt
     3421 tgtgccggtg tgttcagcga tcaagcggcc tgtttagttt tacagaatcg agagaaggtc
     3481 ttggctcgta atcggcaaat cgttttggat aatttgcaaa ttttcaagga ttgggttgaa
     3541 cgaacaccga aggttagctg tgttttccct aatggggttt ctacctcatt tatcaaaatg
     3601 gaaacaaatg agtctagtga gaatttctgt cggcatttgt tagccgatac gggtgtcttg
     3661 ctagtaccag gagaagcttt cgatgtgcct gggcatgcac gtttggggta ctgtgcccca
     3721 acggaaaccc ttgaaaaagg gctagaaatt ttaggccaat atttggaaga gcattaaatt
     3781 taactactaa aggagaaatt gattatggca aaacgtcgta tcgtcgttgc cctgggtggt
     3841 aacgcaattt tatcaaagga tgcttctgct gaagcacaac aacaagcatt acgggatact
     3901 gcaaaatact tggtacaatt catcaagcaa ggagacgatc tgattgtttc ccacggtaat
     3961 ggaccacaag ttggtaattt actgttgcaa caagccgctg ggagtacgga taagaacccc
     4021 gcaatgccat tggatacggc cgtagccatg acccaaggca gcattggtta ctggatgcaa
     4081 aatgctttag atgaagaaat tactaaagct gggttagaca aggacgttac gaccatggtg
     4141 acccaggttg aagttgatcc tgacgatcaa gcgttcacaa atccaagcaa gccaatcggt
     4201 ccgttctaca cagaagctga gattaaggat attaaagcag ctcatccaga atacacgtac
     4261 gttgaggatg ctggacgagg ttatcggcgg gttgtgccat caccacggcc aactggtgtt
     4321 aaagaataca aggtggtgaa cgccttggtt gacgccggaa ttgtgccaat ctctgttggt
     4381 ggcggtggtg taccggttgt tcgagaaggc gatcgattag ttggtcgtga agcagtgatt
     4441 gacaaagact tcgcttctga aaaattagct gaattggttc acgctgattt attgattatc
     4501 ctgacagcgg tggataatat ttacattaac tttaataagc cagatcaaaa gaaattggaa
     4561 acggtcagtg tggctgagtt acaagaatac attgatcagg accaattcgc caaggggagt
     4621 atgctgccta aggttcaagc cgcaatcaac ttcgttaata atagtgaagg tggtaaggcc
     4681 gtggttacct cattggaaaa tgtcggtaat ttcttgaaga acggcgatgg aacaattatt
     4741 acgaaatagg taaataaaca ccaaacgagt ccgtccattt taagctatac tgtataagta
     4801 agcttaaaat agggggactc tttttgtgat aaaaaaaagt gactatccac gctatattca
     4861 aatgttaaaa cggcggccgg agttcagtgg gttcactccc gatgagttta accaactgga
     4921 acagcagatg cgaatcaaag aatatcctaa gggtcaattg ctttttgacc aggcagatac
     4981 gcgttcgcga ttttattttg ttatttcggg tttattacga tcagaacgga tcgatgagac
     5041 tggcgatttt tcattctatt catttattgc agagaacaag ggctttccat atcggggatt
     5101 atttcatgat catgagtatg cctatgcggt taatacgatg acgcctgccg tcgttgtgtc
     5161 atttcctatg gctaattttg aaaacttatt gactcgcaac tcggaaatga tgaagcgagt
     5221 cattgttgaa atggggcaaa ttattaatga gaatgaggat caattgcagc aaatggtaac
     5281 ttctagtgcg agtgatcgcg tgcggaatgc gcttaagatt ctggggcaca aactcggaaa
     5341 tcggctaaaa gatgatcgtt ggtttgtccc ctatgcaatc acgctgattg aactggccaa
     5401 gatggctgga acgaccaggg aaacggccag tcaagtggtt cagcggttgg aggccgaggg
     5461 gcaaattatt tatgagcata agcattttac aatttttatc aaataagttc aacgtaatgt
     5521 tgcattttca acaaaaacca ttatgataga ggcaaggtct tgatttggtc aaagatgaaa
     5581 gggtgttgaa tgcatgacaa tgaagcaggt cgtaattgat aagaactttt ggacaacttt
     5641 tccggatgca cagattaact tgatgtggat tagtgatttt gataatcatg atacggatga
     5701 aaataaggca gagcgacaac aattgttgca cgatgccaca gtggcttcta aacactttac
     5761 aaagattgac ccattccgcg ataatcccgt ggtggcagaa tggcgggatg cctatcaaca
     5821 gtttaagaag cggaagggtg cccgttcatc aatcgaggca ttattaaaac gagctagtca
     5881 aggtcatgag tttatcccga tcgaaccact agtggacgtc tataatagta tctccttacg
     5941 ctatggggtt ccgttgggca tcgaagatcg tgataagatt gcgggggatt tacatttagg
     6001 cctggcccaa ggcggtgaat catttttccc tttgggggct gaagctgatg accctgctcg
     6061 tgaaggtgaa atgatctatt atgatgacga aggtgccgtt tgccgaagct tgaattggcg
     6121 ggaggcgcaa cgaacgatgc tgacagaaga aacaaccaac ggtattgtgg tgatggagtt
     6181 aatgaatgct gatcaagcag cacgggcaac tgccgctatg gctgagttac aaaagttgat
     6241 tcagcattac tttgggattg aaccgggaga aattaaaacc ttaaccaaag aacatccaac
     6301 tgtggattaa caaaatgagt gccgctgtca ttgagacggc ggttttttat aaaaaacatc
     6361 tctgtcacaa gtaacacgtg acagagatgt ttttgtagat taataccaat gatgactttg
     6421 ccaatatttt ttggcttttg tccaagaccc atagcgtccc ttgacgtacg aattagcgac
     6481 tttttcctga ttgactggag ataagttacc atgtagataa gattttagta attggtaacg
     6541 accataacag tttccgttta ctgcgcgata attgtaactt gattcgtgat aagcaatcca
     6601 gttcttagcg gccatttgtt ttttagataa ggaagcgtta attttaacga tttgcttctt
     6661 ctgactagcg gtcagcttag tcgaagcttg ggccgttgtc gttgtttggg gtaagaggtt
     6721 cgttgtgaca tcggtcacca tgccgaaaga aaacccgaat accaacaaaa tggatgcaat
     6781 tttaagtttc atttttgaca tatatttttt aaacactctc tctaatcgaa tttatctgat
     6841 acctagtaat atacgcgaga agtgttgcaa tcgtgttaac gcacagttac tttgtaatta
     6901 aaagcgcgtc acattgatga aatatgttga ttgatgggga gttatcgtca aaagtcattg
     6961 acaaccagtc gaaaagacct atacctgata agtcatttag acgggttgaa tggaggcaaa
     7021 atatgtatga actgttagta ttaggttcgt tactttcgcg ggacatgtct ggctataagc
     7081 tttgtcaggt tttgggtaac gctttggttc cgcgtcgaaa aatttctaat ggcgtcatgt
     7141 atcccttgtt aaataaactg gcggctgcag gggatattac gtttgtaacg gataccacgg
     7201 atgcccgcgg aaagaaagtg gcgcacttaa cggctaccgg tcgtgcgcac ttacatgaca
     7261 tgttagtgac accagtgacg actgacgcta agcgagaatc tttatatcgg tttaaattta
     7321 aggggatggc aactgaaccg gtggctgtgc aaagccaaat tttaaatgaa tacaaagaag
     7381 cgcttttaac cgatctgcaa atttatcagc aggtctatct gcatttgaaa gaaaaactcg
     7441 caacggcttc gatggataga cacgcttcac tagactggag catccgtacg ttagagcttc
     7501 aaattgcgga gagtgaaacg aaaattaaat ggagcaatcg gcagctacag gatttacgac
     7561 taactgatgc tcatggaggt aaaacgaatt atgactaaga gatatcgtca atggataggg
     7621 ctggttgccc tatctttagg cgtctttatg gctttgctgg atgttacgat tgtcaatgtg
     7681 gcattaccaa caatggtgcg agattttaat gaatcgttta ataacgtgca gtgggtatta
     7741 aacgcctact cattggtatt gggcgtaact ttgctaattg tttctaagat tggtgatatg
     7801 tatggcttga aaaaaatctt tgtgttgtca ctaggccttt tcgtattagc atcagccatc
     7861 aacggccttg ccccttcgtt attagtgttg gatattggcc gcggcgtgca agcggttggc
     7921 ggtgccggta tgaattgcac tggcaatggc cttggttgcg gttagcttta aaggtggtaa
     7981 acggggagtc gccctaggga ttttgggatc agtcattggc ttatcatcgg cgtcaggtcc
     8041 tttagttggg ggctacttag ttgcccaatt tggctggcgg tcaatctttt acgtcaatat
     8101 tccaattggg attgtggcga ttattctgac actcatttat gtggatgaag taccggacat
     8161 cagtcgtagc caaaagattg attttgccgg gatgttccta tcggccgcga gcttgtttac
     8221 gttgatttat ggattgattt taaaggaaag tcatccgcac tggggctggc tgagtggcca
     8281 gatgattggc tggtttggcg ctgctattct attcttcatc gtatttattg tggttgagtc
     8341 acggattagt caaccaatga ttaatctaac gatgtttaaa aatccccact ttgtaggaac
     8401 cgttatggtt gcgctggcgt tgggagccgg aatttattca tacaatacgt atctcacggc
     8461 gcttatgcaa aattacatgg gatattctgc gctaggtgcc ggtgttcgac agttaacgat
     8521 tagcatctgg tcattattgc tgggaccaat taccggctat ctgggaaatc gatattctaa
     8581 gaagtggatg atcagcggta gcctattttt gggtggcatt ggatttttac tgttagccaa
     8641 tgcaatgacg gtcaaagtat cgttcatggc cctctggcca ggaatggttt taatgggaat
     8701 tacgaatggg cttgttaatc cgttattgaa tagtgccggg atggagggcg ttgccgttcg
     8761 cgaaatggga atggcctccg ggttaatcaa tgtctttcgt caaatcgggg tcacgctagg
     8821 tattgtgtgc ctggggttgg tccaaaacaa ggtttacgaa acttatttaa cgcagcactt
     8881 cagtcgagtc aatatgccac atgcagctgc gaaggccatc catcaagcat tagtgaatgc
     8941 cggtccattt tctggtcaca gcattgcttt tagttcgcgt ttgagtcaga cgccatttgg
     9001 acatgtggta cagcagattg tttggcaagc atatgccaat ggaactcgcg ccgtttcatt
     9061 agctgctgcc ggcattgtaa ttgctggtgg tttatgtgcg gcagtcttaa tgcgtaatcg
     9121 aaaagctcac taaatcataa tggcatttga agtcgtcagg tattgtcaca taccgtgatt
     9181 tgtgataatc tgacagtagt tgaatagaca aaaacaagag aaatggtcaa tgtcccatct
     9241 ggtcggatgg cgtagcgagc taaggatagt gagagcttag tgtgtcacca attggggata
     9301 accccgtttc tgttgctggc tgaaattatt aaagtaggct acgccgtgac cgacacgtta
     9361 tcaaacggaa cgtatgctag tacgttatta aagttggttt tgaatttaaa acaatttggg
     9421 tggtaccgcg gaaagatctt tcgtccctgt gatagggatg atgggtcttt ttttggtgtt
     9481 gcggtgattc atggaaggag aaataaggtc atggtagacg ttttagttaa aaatttattt
     9541 agcgatcggc attttgctga agatgaagtg gtgacattac acggttgggt aaagacggtc
     9601 cgtggatcca agcgggttgg ttttatcgaa ttaagtgatg ggtcgacgat taagcacgca
     9661 caaattgtga tgcaaagtga tctcgagaat tatgcggaaa tgacgaaatt accattgagt
     9721 tcgacgatta aagttgtggg gacggtggtt tatacaccgg atgccaagca accgttggaa
     9781 attcatgcac aagaagttgt attagaaggg gcttcagata acgattatcc actgcaaaag
     9841 aaaaagcatt cttacgaata cttgcggacg atggcccatt tgcggccacg gacgaacaca
     9901 ttctatgcgg ttttccggat tcgctcgttg gcagcgttcg ccattcatca atatttacaa
     9961 gaacatgggt ttacgtacgt taacacgccc attattacca gtagcgatag tgaaggtgct
    10021 ggtgaaatgt tccgggtaac gacgttagac atgaacaact taccgaagac tgaagatggc
    10081 cgggtggatg atcacgagga cttctttaaa aaggaaacga atctgacggt tagtgggcaa
    10141 ttaccagttg aagcatttgc cttagcttta cggaacgtgt acacgtttgg cccagccttc
    10201 cgggcagaaa actcgcatac atctcggcat gcctctgaat tttggatgat tgaaccagaa
    10261 atggcttttg ctgacctgca ggacactatc aatgaggctg aaggcttact gaagtatgtg
    10321 gtccaatacc tattggatca tgcgcaagac gagttggctt ttctagacag tgctgttgat
    10381 gatgacttgc tgaaccgttt gcaccagact tgcgatgaaa agtttgcgca aatcacttac
    10441 acacaagcga tcgaagagtt gaaaaaagcg ccagttgatt ttgacgtgcc cgtttcatgg
    10501 ggacttgact tacaagcaga acatgaacgt tatttgtgtg aacaagtgta taaacggcca
    10561 accttcctga cggattatcc taaggaaatt aaggcctttt atatgcgaga caatgaagac
    10621 gggaagacgg ttgcggccgc tgacttgttg gttccccgaa tcggtgaatt aatcggtggc
    10681 agtcaacgtg aagaacgtca ggcccaatta gcccagaaga ttaaggacta taacttgccg
    10741 cccgaagagt atcaatggta cttggatcta cgtaagtatg gtgaaacacc acattctggc
    10801 tatggtattg gttttgaacg gttactgatg tatgtgactg gaatggaaaa cattcgcgat
    10861 gtgattcctt acccacggac accgggtaac gctgaattct aagacattag acgcatagtc
    10921 tttaaataaa atttcgaaga caacgttaaa caatcaaaaa ggcaggttca acggaaaata
    10981 ccggtgaacc tgccttttaa ttttcttcag taatgctcgt cgtcatggca gccgtgattt
    11041 tacggtaaac taggacggtt cctagaaaga agctagcggc taaggtagcc gcaatcggga
    11101 gatggatgaa catggttggt ggcaagacga gtgccaagag cggaaacgca taggccgctg
    11161 gcagttttag gttgagcaga gccagcagca gtaaaacgag tggcaagctg atcaaggttg
    11221 ctaggagcca tgaggttacc agtaagtgtc caacaacccc aatggttgct gcgccactga
    11281 gtgcggcaat ttgtttaagt gctagtttac ccgagtaggt tgggcgctgg aggacttcaa
    11341 agaagaccac tagtaccggc ggaattccgg ccatttgagg ctgtcccgct agacaaacac
    11401 cgataatcca gactatggca actgccgcaa agcctaaaat atgttgaaaa tgaatcggat
    11461 cgctggcaat cgctcggcga tagtggccct gtcgtaagac gccgatcatg agaattagcg
    11521 taaacaagaa aatggccccg ataaatgacc agtgagttgc attaacaata attggtaaaa
    11581 gtccggtggc aaaggccggt gctaaggggg aacgtaattc acgcaagagc acgagaatgc
    11641 ccactaaagt tagcgaaatt ttaatggggt agttaaccgg aagctggttg attaaaaagc
    11701 caataaccgc cgtaccggaa ggcgctaaaa aaattttgta aggttgatgg agccagcgtg
    11761 gattgtgata aatccacata ccagcagtta atgcagcaat ttccggcaag ataatttctt
    11821 gatcgtgcaa gaacattgct ccagcgacca tcagaaggac taaagcgaag ccgatcagat
    11881 agtcacgact gacgtgagtc ataaacttca taagtaacga ggcgcctcct aaatattatt
    11941 ccgatgaaaa cacaagcatt tttgattgta acatacctgt cgatgagatt caggtgaact
    12001 atttttttgc agattaacta gtgataagcc gggtgatcat tatgcgtaaa tagcctgttg
    12061 gagaattatt cacaggtgag cgtaaaggtt gcaatcggaa atactaatcg gttattatga
    12121 tgttaacgat aggaatcaac taatgcaaaa aggaggcgtt atcttatgct cggatggtta
    12181 tggtcattaa tcgttggtgc gattatcggt gcggtggcag gtgcaattac taatcgcggc
    12241 ggttcgatgg gctggattgc caatatccta gccggcttga ttggttcttg gttaggacaa
    12301 gcactattag gttcttgggg tccaacttta gccgggatgg cattagtccc ttcaatctta
    12361 ggggccatca tcttaatctt gattgtttca gcaatctttg gtgttcgcgg caaggccaaa
    12421 taaggcggtg atccgatgcg acgaggcaac aaaggacttt tgacgattct aggactgatt
    12481 ctactagcct tgggcatctt tcagctcggc tggtggctgc cgattccggg actttcagcg
    12541 tggagtttag aaatgagcta tacccaaatg gcttggttga aatatgtttt agccggggcc
    12601 gtgattatta ccggaatcgt tggtttggga ttagtggtta tcggtatctt caaaccaata
    12661 cgtgagaagc aatggcaatt caccaatcgg cttggtatgt tggaagtgcc acaggcagcg
    12721 ctagaaaaag cgttacgtca ccaactggtt gaacaggtgg gcttagttga cccccgagta
    12781 acggtgaaat tgttacgcca ccggcgtgcc cgagtgaccg ccatcgctca ggtcagtgca
    12841 acggatcaga ttgatccgct ggcacaacag gctagccaag tgattgatgc ttatttacag
    12901 caacaattag atttgacggc cgtcaaaccg gttgtccggt tatcaccagt tgatcggcaa
    12961 cggcacgtgt cagtcgtgta aaggagggag tggcatgagt aatggcgcat atggcgcact
    13021 gtggggtctt gttttgggac tcgtatgggt gttccaaagc ttccccgcaa tgttgttagt
    13081 tgctgtgttt ggcctagtgg gctggggaat tggtcggttt gtccgcttag atctttcggc
    13141 cctaggtaaa cggattgaac aacttttatc gagataatta aaggaggggt cttatgacca
    13201 cagaaaaacc aacattaacc acgaagttaa cgtttgaaga tgatgtgatc aagaagattg
    13261 ctggactggc atcgcgcaat attgatgggg tcttagcatt agaaggtggg atgatcagta
    13321 atctcacgaa ccgattccgc aatgattctg atccaaccca aggtgttcaa gcccaagtcg
    13381 gcgaacaaca agccgctctc gacatgacga ttaccgttga atatggtaag gatatgcgcc
    13441 agatttttaa tcaactctgc caacgggtcc agcaggatat tgaacgcttt actggattag
    13501 aagttgttga tattaaagtt catattaatg acgtcatgag taagcaagaa tggcaagagc
    13561 aggcagctgg taagcctaat tctaccgttg acactgacga caaggtcaaa taaaggaggc
    13621 cctcatggac aaacaacctg aagcaacgca aacaattatc tttgatgata tggtgttaga
    13681 aaagattgcg ggtaagacgg cgagcgaagt cgatggtgtg ctgagtttac aaggcaacct
    13741 gattgataat ttatcggatc gattaacaga gagtgatcga ccgcaatctg gcgtcgatat
    13801 tgaactggat gaccaacaaa agaccgtggc cattgaactg gatgccatcc tagaatatgg
    13861 gaaacgtgcc gaagaaattt taaccaaagt gacgagtaag attaccagtg cggtgaccac
    13921 catgactggc tatcgagtga ccgaggttaa gcttcgggtc aaagatatgc tgaccaaaga
    13981 cgaatggcag caacgacaac agtcatctcg tagtaaaaag aaaaaggacg actagtcact
    14041 agccaatagc tagcgctggt gctctactaa ataaaggacg ctttcagaat gttgtcagtt
    14101 ctgaaagcgt cctttttatt tgattacatg gtagtcggcc gaataggctt attcatcaca
    14161 caaagttcgg gccatcaatg ccggatcaat gtgtattgtg ccccaagtac agatggcatc
    14221 taagatcgga attagtgatt ggcccatggg tgttaatgca tattcgacat ggggttgagc
    14281 ggtatgaaag tcgtgacggg taatcaaccc atccgcttgt aattcacgta attgactcgt
    14341 gagtgttttg tgtgagacgg cttgaatgtg atgttgtaag tcagcgaatc ggcaatggtc
    14401 atcttcgtct agttcataaa gaatcatgat cttccatttg ccctgaatca gttgcatggt
    14461 ggcgtcaaat tcatttaaaa agcgtggtgc tatgagtggt tgcttatcca taaagggtcc
    14521 tttcggggga aacggtcagt cgtagttacc ccaaagtgcg tacttgtttt tagttcgcct
    14581 cccattatac tgagaattgt tgagaaatac agagattgtt atgaaagatt tttaggaggt
    14641 acattatgaa aaaattagtg gtgatcacgg gggctagttc tggatttggc caggagattg
    14701 ctaaaatctt caatgctgac ggtttcccga ttttattact gggccggcg
//
