LOCUS       c00075_gnlPro..        16619 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CFBAJCOI_84.
ACCESSION   c00075_gnlPro..
VERSION     c00075_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 17:01:44
            Original ID  :: gnl|Prokka|CFBAJCOI_84
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16619
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16619
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:6619]"
                     /cutoff="20000"
                     /detection_rule="(minimum(2, [Aldedh, BMC, Cob_adeno_trans,
                     EutN_CcmL, Fe-ADH, Fe-ADH_2, PDU_like, PTAC, PduV-EutP])
                     and Dehydratase_MU and Dehydratase_SU and Dehydratase_LU)"
                     /neighbourhood="10000"
                     /product="pdu"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..6619
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="20000"
                     /detection_rule="(minimum(2, [Aldedh, BMC, Cob_adeno_trans,
                     EutN_CcmL, Fe-ADH, Fe-ADH_2, PDU_like, PTAC, PduV-EutP])
                     and Dehydratase_MU and Dehydratase_SU and Dehydratase_LU)"
                     /neighbourhood="10000"
                     /product="pdu"
                     /protocluster_number="1"
     cand_cluster    1..16619
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aldedh, BMC,
                     Cob_adeno_trans, EutN_CcmL, Fe-ADH, Fe-ADH_2, PDU_like,
                     PTAC, PduV-EutP]) and Dehydratase_MU and Dehydratase_SU and
                     Dehydratase_LU)"
                     /kind="single"
                     /product="pdu"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16619
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="pdu"
                     /region_number="1"
                     /rules="(minimum(2, [Aldedh, BMC, Cob_adeno_trans,
                     EutN_CcmL, Fe-ADH, Fe-ADH_2, PDU_like, PTAC, PduV-EutP])
                     and Dehydratase_MU and Dehydratase_SU and Dehydratase_LU)"
                     /tool="gutsmash"
     CDS             complement(2..274)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     Dehydratase_SU"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_1"
                     /sec_met_domain="Dehydratase_SU (E-value: 9.8e-21,
                     bitscore: 65.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEIDDLVAKIVQQIGGTEAADQTTATPTSTATQTQHAALSKQDY
                     PLYSKHPELVHSPSGKALNDITLDNVLNDDIKANDLRITPDTLRMQ"
     CDS             complement(287..1006)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     Dehydratase_MU"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_2"
                     /sec_met_domain="Dehydratase_MU (E-value: 1.4e-34,
                     bitscore: 109.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VAQEIDENLLRNIIRDVIAETQTGDTPISFKADAPAASSATTATA
                     APVNGDGPEPEKPVDWFKHVGVAKPGYSRDEVVIAVAPAFAEVMDHNLTGISHKEILRQ
                     MVAGIEEEGLKARIVKVYRTSDVSFCGAEGDHLSGSGIAIAIQSKGTTIIHQKDQEPLS
                     NLELFPQAPVLDGDTYRAIGKNAAEYAKGMSPSPVPTVNDQMARVQYQALSALMHIKET
                     KQVVMGKPAEQIEVNFN"
     CDS             complement(1027..2703)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     Dehydratase_LU"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_3"
                     /sec_met_domain="Dehydratase_LU (E-value: 3.6e-301,
                     bitscore: 990.4, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKRQKRFEELEKRPIHLDGFVKEWPEEGFVAMMGPNDPKPSIKIE
                     NGKVTEMDSKPAADFDLIDLYIAKYGIKLENAEKVMAMDSTKIANMLCDPNVPRKDIIE
                     ITTAMTPAKAEEVISKLNFAEMIMATQKMRPRRTPATQCHVTNIRDNPVQIAADAADAA
                     LRGFPEQETTTAVARYAPLNAISLMVGAQTGRPGVITQCSVEEAEELSLGMRGFTGYAE
                     TISVYGTDKVFTDGDDTPWSKGFLASCYASRGLKMRFTSGSGSEVMMGYTEGKSMLYLE
                     SRCIFITKASGVQGLQNGGVSCIGIPGSVPSGIRSVLGENLLCMMLDLECASANDQAFS
                     HSDMRRTERLLGQFIAGTDYISSGYSSTPNYDNTFAGSNTDGLDYDDYYVMERDLAING
                     GIHPVDEQTIIKARNKAARALQGVFEDLGLPKITDEEVEAATYANTSKDMPERNMVEDM
                     KAAQDLMDRGITGVDIVKALFNHGFKDVAQAVLDLQKQKVCGDFLQTSAIFDSKWHVIS
                     AVNDANDYQGPGTGYRLEEDTEEWERIKNLPFAIDPQNMQL"
     CDS             complement(2718..3434)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 48.4; E-value:
                     2.4e-15)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_4"
                     /sec_met_domain="BMC (E-value: 1.1e-15, bitscore: 48.4,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNFLNSTSTVPEFVGASEIGDTIGMCIPSVDALLLDHLHVQKRF
                     TVIGILSSRTGAGPQIMAMDEAVKATNTEVIDIEMPRDTKGGAGHGVLILVGGYDPSDV
                     RSAIQVALDNLSRTFGDVYNSAAGHLELQFTARAAGACHMAFGAPEGKAYGLICGAPSG
                     IGVVMADTAIKTAGVNVLTFASPGHGTSFSNEGIVHISGDSGAVRQAVIAGREVGLKLL
                     AQLGENPVNDFPSYIR"
     CDS             complement(3554..3832)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 100.5; E-value:
                     1.3e-31)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_5"
                     /sec_met_domain="BMC (E-value: 5.8e-32, bitscore: 100.5,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQEALGLIETKGLVAAIEAADAMVKAANVDLVGQEKIGHGLVTT
                     MVRGDVGAVKAAVDAGVAGAENIGEVLSSYVIPRPHTDVEKILPQKK"
     CDS             4134..5222
                     /locus_tag="ctg75_6"
                     /transl_table=11
                     /translation="MTTYSPSQENYRELAHLLARFTSLTQIKTIFYDFTGILLKDDFVY
                     INHSAIEDNLAQLTFSDYAVFPVSRNIQMWGAILCESVNVSKKRLFLSRSYLENLMEQI
                     FDEDTLGKVSVWEPLTSDQVGQINNLHALFHPTGDTNPLQAVLAPNAVIAGHTIDNDEA
                     FRSISLAIDYIQKNIQRPISLNEVAQRAYLSPSYLSRLFKKYLHVNFIEYVNNQKIALA
                     QEKLSLTLTPINQISNQIGFTQTSYFTKIFKKKTGITPSEFRQRNHTIQKIYTIPRELN
                     WDTNDSVIDVTKNYFKSHHITYHTDSEEGATYVNSIGELNDAKGNRGWIYTVDGQQPTQ
                     SADEIATHDKSVIQWVYTDYSN"
     CDS             complement(5275..6018)
                     /locus_tag="ctg75_7"
                     /transl_table=11
                     /translation="LFHEYDKGRCFVMSGFIGEFFGTMILIVLGAGTGASVNLKKTYGQ
                     GSSWTFISIAWGLAVTMGVYVAGALGSDGHLNPAVTIGFAVFGFFPWSSVVPYLLGQFL
                     GAFVGAVLVIIQFYPHFKATPSVEEGNTVGIFATRPAIASPLFNFLSEVIATWAFIFIL
                     LNLGDFTQGLKPFIVGTLITVVGMGLGTTTGFALNPARDWGPRLAHSLMPIPHKGSSEW
                     SYAWVPMCGPIVGGILAAGLQVLVK"
     CDS             complement(6188..6619)
                     /gene_functions="biosynthetic (rule-based-clusters) pdu:
                     PduV-EutP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_8"
                     /sec_met_domain="PduV-EutP (E-value: 1.7e-56, bitscore:
                     180.8, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRAMFVGAIGCGKTTLLQQLKHQTIAYDKTQSVEFFQNIIDTPG
                     EYIEHRQMYTFLATTAMDANVVVLIQSATDQRLIFPEAFATMFGCPVVGVITKLDLVTT
                     DKDIAWAQQQLRQAGATQIFQVSGLTGTNVDQLRAYLDD"
     CDS             complement(6849..8216)
                     /locus_tag="ctg75_9"
                     /transl_table=11
                     /translation="MKSKAPVSKNERLDVTITDLTYQGLGVAKVEDFPLFIENTLPGEE
                     VTIQVTKVQSHYGFARAVAWTQESPDRVKDVDKTYRQTGIAPLQHLAYPAQLKFKQHQI
                     AELFSKSHQDVEVAPTMGMDNPTQYRNKAQVPVRMIKGQLETGFYRQHSHELIPLTDFY
                     IQDPAIDAAIIKVRDLLRQFEIPAYNEVSDKGVIRNIMVRRGYYSHEMMIVLISRTQKI
                     PSQAQLVDQIHQALPEVTSIVLNVNAKKTNVIMGNVTRVLYGKPTIEDTLMGLTFAISA
                     RSFYQVNPQQTEKLYQMAIDKAGLTGAETVIDAYCGIGTISLALAKHAKQVYGVEIVPE
                     AIEDAKVNAQKNHLSNVTFAVNKAEDQMAEWQAAGIKPDVIVVDPPRKGLAESLIDSAA
                     KMAPKKIVYVSCNPATLVRDVARFTELGYHVDGPVQPVDQFPQTPHVESVTVLVKD"
     CDS             complement(8288..9307)
                     /locus_tag="ctg75_10"
                     /transl_table=11
                     /translation="MRKRARVIYNPTSGREALKKDLIDILAVFEQAGYETSAYATTPAP
                     NSARDEATRAAKAGFELIVAAGGDGTINQVVNGLAGLAHRPKMAIIPAGTTNDYARALH
                     IPREDPLAAAKVVLKNQMIKMDIGQAGDSYFINIAGGGLLTELTYDVPSNLKSIFGYLA
                     YLVKGAELLPRIKPIEMDLTYDGGHFRGQASMFLLALTNSIGGFEQIVPDAALDDGKFT
                     MIIVKTASMPEILRLMGLVLNGGKHINDPHIIYEKTSKVIARPVKDRMMINLDGEYGGD
                     APMKFHNLRQHIEMYANLDAIPDSAVTSESAELLEAEEKFVKQVEELPATADATTKDK"
     CDS             complement(9327..10748)
                     /locus_tag="ctg75_11"
                     /transl_table=11
                     /translation="MNFETTIGLEVHIELKTHSKIFSPSPVAYGADPNANTNVIDWGYP
                     GVLPTTNKGVVADGIIAALALHATVEQHTHFDRKNYFYPDNPKAYQITQSDKPIGHDGW
                     VEIDVDGVKKKIGIAEMHIEEDAGKNTHERDYSYVDLNRQGTPLIEIVSKPDIASPAEA
                     YAYLEALRQRIQFTGISDVKMEEGSMRVDVNISVRPVGQQKFGTKTELKNLNSFNYVQR
                     GLEYEEKRQQQVLMSGGAVQQETRRFDEKTGETILMRVKAGADDYRYFPEPDLPALNIS
                     DDWIKELDAAMPEMPGKRRERYVNELGLTDYDAMVITQTKEMSDFFNATVALKADPKMA
                     ANYLQGDVNAYLNDKQVDLQATKLTPEHLAGMINLITDGTISSKMAKKVFKAITEGEDP
                     KAFVEANGLVQLSDPAKLQPIIDDVLSANPQSIEDFNNGKKRAVGFLVGQIMKQTHGQA
                     NPQVVNKLLMAALQQ"
     CDS             complement(10748..12217)
                     /locus_tag="ctg75_12"
                     /transl_table=11
                     /translation="MDYFKTDLASLHADLVAKKISARELTQATFDNIKTTDAQVDAFLT
                     LNEDAALKQATKIDEQGVATDQPLAGIPVALKDNIVTKGLKTTAASKMLANFNPVYDAT
                     VTEKLAQAQMITVGKTNLDEFAMGGSTENSAFKTTKNAWDYTKVPGGSSGGSAAAVASG
                     QVLAALGSDTGGSIRQPAAFNGIVGLKPTYGRVSRWGLIAFGSSLDQIGPMTRSVKDNA
                     TMLSAIAGHDEHDLTSSTQPVPDFAADLTDATSVKGMRIGLPKEFLADGVADDVKQAIL
                     AAADTYRQLGATVDEVSLPHNKYGVAAYYIIGSSEASSNLQRFDGIRYGHRADDVKNLE
                     DVYVKSRSEGFGDEVKRRIMLGTFSLSAGFYDAYFLKAAKVRTVIMNDFKAVLKDHDFI
                     MGPVAPTPAFGIGDEIKDPITMYMNDVLTIPVNLAGLPGLSLPAGFSQGLPVGMQLIGR
                     PFDESTLYKAGYAFEQNTDFHLQVPTLGGQH"
     CDS             complement(12218..12529)
                     /locus_tag="ctg75_13"
                     /transl_table=11
                     /translation="MANRINREQVQHVASLAKLEFTDAQLDAFTPQLDDIIGLFETLSE
                     VDTDGVEATSSVTDQLNVMREDVADNWGQSQSLLKNAPEAARGFIKVPAIIDESEDND"
     CDS             complement(12852..13073)
                     /locus_tag="ctg75_14"
                     /transl_table=11
                     /translation="MTVENSCVLNWVVIVRPLVATNGLERTGHDFKPSRALVLKVGLIL
                     STLKTRAKDNDGTGPICRFPPSYRGVTG"
     CDS             complement(13169..14314)
                     /locus_tag="ctg75_15"
                     /transl_table=11
                     /translation="VKRLRTFIALAAVPLFLAACGNLSSSSISGTSGTSKSSKTQLTGQ
                     SSDGDYEGVIKSGHYQTSKSRGVTNSQDSGNTYNVKSFENGMLGVSKKVFSTKSYVFQE
                     GQYLSSSTVQNWLDRKTKSNPTGLNPKSNGSTSPTKRNPVYIQALEEQDYMTQKNNKLS
                     LGGVTIGIAVNSVDYYKKTQYGATYETKITKAEGEAYAKKAANTVLKRLRKKSALKNVP
                     IVIAIYRQASNDSLVGGNFIAYSENKGSATTVSKWNALSEKNYVFPIESGSSSPNSNDE
                     TSFTNFKSQVENFFPNLSGVTAQAHYSGNTLTGMHVNITTQFYSQTEIISFTQYLQTAA
                     QKYLPSSVPIDITVSSTDSVQSFLSRSSGAKKFTSHVFNSY"
     CDS             complement(14337..16367)
                     /locus_tag="ctg75_16"
                     /transl_table=11
                     /translation="MTDKPIKTLTVEQAAEEAADLRPQLLEWGKQYYEADAPSVEDDVY
                     DRVYARLVALETAFPEIVTPDSPTQRVGGSSRSDLPKVTHDIPMLSLGDVFSLDELTEF
                     DERLRGNVDTPFDYNCELKIDGLAISLRYENGKFVQGSTRGNGQIGEDITANLKTIKSI
                     PQTLSRPLTIEVRGECYMPKAAFLALNERREAAGQAPFANPRNAAAGSLRQLDTRVTAD
                     RQLATFMYNVADYEPLTTRTQSGLLDELAELGFTTNATYRVAHDMADVAAYIETYQAQR
                     TELAYGIDGIVIKANDLPLQRSLGATVKVPRWAIAYKFPPEEVQTRVLDIEWTIGRTGV
                     VTPTAIMEPVALAGSTVARASLHNPDYLIAKDIRIGDTVLLHKAGDIIPEISQYVAAKR
                     PAEAKAYVIPTTCPSCGAELVHLDDEVALRCINPRCPAQLAEGMNHFASRNAMNIAGLG
                     PQIVAQLFDRNLVQDVADLYRLTTDQLLTLDKFGEKSAQNLLTAIDNSRNNSLERLLFG
                     LGIRHVGAKAARSLAAAFGDMASLMAADSEQISAIDTVGGIIADSVVTYFANTQVHELV
                     AKLQAVGVNMTYTSGTPATNSTSEFTGKRVVLTGKLQELTRPQATEWLEQHGATVTGSV
                     SKKTDLLIAGEAAGSKLAKAQSLDVPVWNEAQLQAAMDETK"
ORIGIN
        1 cttgcatccg taaggtatcc ggcgtaattc gtaaatcatt ggccttaata tcatcgttga
       61 gaacattatc caaagtgata tcgttcaaag ctttcccaga cggtgaatgt acgagctctg
      121 ggtgcttaga gtacagtgga taatcttgtt tcgataatgc tgcatgctgc gtctgcgtcg
      181 ccgttgacgt aggcgtggca gtcgtctgat cagcggcctc agtgccacca atttgttgga
      241 cgatttttgc tactaagtca tcaatttcac tcatgaccca ttcctcctag ttaaagttga
      301 cttcgatttg ttcagcgggt ttccccataa cgacctgctt cgtttccttg atatgcatca
      361 aggcagacaa ggcctggtat tgaacccgag ccatttggtc attaaccgtt ggaacggggc
      421 ttggtgacat tcctttagcg tattcggctg cattcttgcc gatagcccgg taggtatcac
      481 catccaagac aggtgcttgt gggaataatt ccaagttgga caatggttct tggtcctttt
      541 ggtgaatgat cgtcgtcccc ttggattgaa tggcaatggc gatgccagaa cctgataaat
      601 gatccccttc ggcaccacag aaggaaacgt cagaagtccg gtagactttc acaattcggg
      661 ccttcagtcc ttcttcttca ataccagcaa ccatctgtcg taaaatttct ttatgactga
      721 ttccggtcaa gttatggtcc atcacttctg caaaggctgg tgccacagca atcacgactt
      781 catcacgtga atagccgggc ttggcaaccc caacgtgttt gaaccagtca actggttttt
      841 ccggttctgg gccgtcacca ttaactggtg cagccgttgc cgtcgtagct gatgacgctg
      901 ctggtgcatc agctttaaat gagattggcg tgtcccccgt ttgggtttcc gcaatcacat
      961 cacggataat attccgcaat aagttttcat caatttcttg agccacagtg ttaaccccct
     1021 tttcgactaa agctgcatgt tttgtggatc aatggcaaac ggtaagttct tgatgcgttc
     1081 ccattcttcc gtatcttctt ccaaccggta acccgtacca ggaccttgat agtcattggc
     1141 atcgttgacg gcggaaatga catgccactt gctgtcgaaa atagcggatg tctgtaagaa
     1201 gtccccacaa accttttgct tttgcaaatc taaaacggct tgggcaacat ccttaaatcc
     1261 gtggttgaac aaggctttaa caatatcgac cccggtaatg ccgcgatcca tcagatcttg
     1321 ggcggccttc atatcttcaa ccatgttccg ttctggcata tccttagagg tgttggcgta
     1381 agttgccgct tccacttctt catcggtaat cttaggcaaa cctagatctt caaagacacc
     1441 ttgaagggcc cgtgcagcct tgttgcgggc tttgatgatt gtttgttcat caactgggtg
     1501 aatcccaccg ttgatggcca agtcgcgttc cataacgtag taatcatcgt agtccaagcc
     1561 atcggtgttt gaccccgcaa acgtgttgtc atagttaggt gttgaggagt aaccagaaga
     1621 aatgtaatcg gttccggcaa tgaattggcc taataaccgt tctgtccgcc gcatatcaga
     1681 atgggagaac gcttggtcat tagcagacgc acattcaagg tcaagcatca tgcacaatag
     1741 gttttcaccc aagacggagc gaatcccaga aggaacagac cctggaatcc caatacaact
     1801 aaccccaccg ttttggaggc cttgaacacc ggacgctttg gtaatgaaga tacaacgtga
     1861 ttcgaggtat aacatggact taccttcggt ataacccatc ataacttcgg aaccagaacc
     1921 agacgtaaac cgcatcttca acccccgcga agcatagcag gaagctaaga agcctttgga
     1981 ccatggtgta tcatcaccat cagtgaagac cttatcggta ccgtaaacag aaatggtttc
     2041 ggcgtagcca gtgaagcccc gcatccctaa actcaattct tctgcttctt caaccgagca
     2101 ttgggtgata acaccaggac gaccggtttg cgcccccacc atcagcgaga tggcattcaa
     2161 tggggcatac cgggcaacgg ccgtcgtggt ttcttgttcc gggaaacccc gtaaggcagc
     2221 atcggcagcg tcagcagcaa tttgaacggg attatcccga atattggtaa cgtgacattg
     2281 cgttgctggt gtccgccgtg gccgcatttt ttgcgttgcc ataatcattt cggcaaagtt
     2341 caatttgctg ataacttctt cagctttggc cggcgtcatc gccgttgtaa tctcaatgat
     2401 gtctttacgt ggcacattgg ggtcacagag catattggcg atcttagtgg aatccatcgc
     2461 cattactttc tccgcatttt caagcttaat gccatatttt gcgatgtaga gatcaatcag
     2521 atcgaagtca gcagctggtt tactatccat ttcagtaacc ttgccgtttt caatcttgat
     2581 gcttggcttt gggtcattag gccccatcat ggcaacgaag ccttcttcag gccattcctt
     2641 aacgaaaccg tctaaatgga tcgggcgttt ctctaattct tcaaatcgtt tttgacgttt
     2701 caattaaaaa tcccccttta acgaatgtag gatggaaaat cattaactgg attttcacct
     2761 aattgcgcta acagtttcag accaacttca cgaccggcaa tcacggcttg acgaacggca
     2821 ccggaatctc cactgatgtg gacaatgcct tcgttagaga agctggttcc atgacctgga
     2881 gaagcaaagg tcaagacgtt gacgccggct gtcttaatag cggtatcagc catcacaacc
     2941 ccaattcctg aaggtgcccc acagattaaa ccgtaagctt taccctctgg agcaccaaag
     3001 gccatgtggc aagcaccggc agcccgggcc gtgaattgca gttccaaatg cccggcggcg
     3061 gaattataca catcgccgaa ggtacgactt aagttatcta gggccacttg aatggctgac
     3121 cgcacatcag atggatcata cccaccaact aagattaaaa cgccgtgacc agcaccacct
     3181 ttagtatccc gtggcatttc aatatcaata acctcggtat tggtggcctt aacggcttca
     3241 tccatcgcca taatttgagg accagcaccc gtgcgggaac taagaatgcc aatcactgta
     3301 aagcgttttt gcacatgcaa atgatcgagc aataaagcat caacactagg aatacacata
     3361 ccaatcgtgt cgccaatttc actcgctccg acaaattctg gaacggtgct cgttgaattt
     3421 aagaagttat ccattatttt tcctcccgat gactgcgagg ccggtttaac cgtgaccccg
     3481 tgacgcagaa gttcttccat gatttgattc attaactgct gattggtcat catttattta
     3541 cacatctaag atgctatttc ttttgaggta aaatcttttc aacatcggtg tgtggacgtg
     3601 gaataacgta gctagataga acttcaccaa tgttttcagc gccagcaaca ccagcatcaa
     3661 cagcggcctt cacagcacca acgtcaccac gaaccattgt cgttaccaaa ccatgaccga
     3721 tcttttcttg tcccactaaa tcaacgttag cggccttgac cattgcatcg gcggcttcaa
     3781 ttgcagcaac taaacccttt gtttcgatta atccgagtgc ttcttgttcc atgataaaac
     3841 ctccatttat tggctgggca acccacgctg cccttcttct aaaacgcttt cattatattt
     3901 gaatgattta gcactatttc gaccgaaata gcacatttga ctacaaaata atcaaaatta
     3961 ctaaatgcca ctactaaaag ctcaatattt tacaagcagt taaacaaatt gcgcttgata
     4021 tagcaatctg tttaacttac aattaatttg tgatagcgga ttcatcacta ttttgtcagc
     4081 aaattatata taaaatcatc taattatcca aactcaatct gggggctgtt actatgacca
     4141 cttattcacc aagtcaagaa aattaccggg agttggcaca tcttttagca cgatttacca
     4201 gtctgacaca gatcaagacc atcttttacg attttacggg aatcctctta aaggatgatt
     4261 ttgtgtacat taatcactcg gcgattgaag acaatctcgc gcaactgacc ttctcagatt
     4321 atgccgtttt tccagttagc cgcaacattc agatgtgggg cgccattctt tgtgagagtg
     4381 tcaatgtttc caagaagcga ttatttctgt cccgctctta tttggaaaac ttgatggaac
     4441 aaatctttga tgaagacact ttaggtaaag tcagcgtctg ggaacccctc acttctgacc
     4501 aagtaggcca gattaacaac ctccacgccc ttttccatcc gactggcgat accaacccac
     4561 tgcaagcagt cttggcgccc aatgccgtca ttgctggtca tacaattgat aacgatgagg
     4621 cgttccgcag tatttcactg gcgattgact atatccaaaa aaacatccaa cgaccgattt
     4681 cgcttaacga agtggctcag cgcgcttact tatcaccgtc ttacctcagt cgcttattca
     4741 aaaaatacct tcacgttaac ttcatcgagt acgtgaataa ccaaaagatt gctttggccc
     4801 aagaaaaatt atccctaacc ctgaccccca tcaatcaaat ttcgaatcaa attggcttta
     4861 cccaaaccag ttacttcacg aaaattttta aaaagaaaac ggggatcacc ccatccgaat
     4921 ttcgccaacg caatcataca attcaaaaaa tctatactat tccacgtgaa ctaaactggg
     4981 acacgaatga ctcggtcatc gatgtcacca agaattactt caagtctcac cacattacct
     5041 atcacactga ttcagaagaa ggtgcgacgt acgttaatag tatcggcgaa ttaaacgatg
     5101 ctaagggaaa ccgcggttgg atttacaccg ttgatggcca acagccaacg caatctgctg
     5161 atgaaatcgc cacacatgat aaatcagtca ttcagtgggt ctataccgac tactccaatt
     5221 aaaaaagagc gataaccaga acttatccgg ttatcgttct ttaattttga tcaattattt
     5281 cactaaaacc tgtaagccag cagccaaaat gccaccgaca atcgggccac acattggcac
     5341 ccaagcatag ctccattcac tagaaccctt gtggggaatt ggcattaatg aatgtgccaa
     5401 ccggggaccc caatcacgag ctggattcaa agcaaaacca gtcgtggttc caagccccat
     5461 tccgactacc gtaattagcg tcccgacaat gaatggcttc aacccctggg taaagtcacc
     5521 taagttcaac agaataaaga tgaatgccca ggttgcgatc acttctgaca agaagttaaa
     5581 cagtggactg gcaattgcgg gacgggtcgc aaagattccc accgtattac cttcttcaac
     5641 agacggggtt gccttgaagt gaggataaaa ttgaataata actaatacag cacccacaaa
     5701 agcccctaaa aattgcccca acaagtatgg gaccacgctg gaccatggga agaatccaaa
     5761 gactgcaaac ccaatcgtca ccgctggatt caaatgacca tcagaaccca aggcccccgc
     5821 tacatagacg cccatcgtca ccgctaatcc ccaggcgata ctaataaagg tccagctact
     5881 gccttgacca taggtctttt tcaaattaac actagcacct gttccagcac ctagaacaat
     5941 caaaatcatc gtgccaaaaa attcaccgat aaaaccactc atcacaaaac acctgccctt
     6001 atcatattca tgaaacaatc gtagtctagc acaaacgacc cccgtatttt tttcagctaa
     6061 atggaaattt ttgttttatt tgtaagcggt atcattatta atccatttta gcttcggtta
     6121 ggcgattatt ttatgattat cctgccacgg atttaccacc cctacaaaat aatcttaata
     6181 ccccgaatca gtcgtccaaa taagctcgta actgatcaac attagttccc gtcaacccag
     6241 atacctgaaa aatttgtgtg gccccagctt gacggagttg ctgttgtgcc catgcaatat
     6301 ccttatcggt ggtcaccaag tccaatttgg tgatcacccc caccaccggg caaccaaaca
     6361 tcgtcgcaaa agcttctgga aaaattaatc gttgatctgt tgcactctga ataagaacca
     6421 cgacattagc atccatcgct gttgtcgcca aaaaagtata catttgtcga tgctcaatgt
     6481 attctcccgg tgtatcgata atgttttgga aaaattcaac cgattgcgtc ttatcataag
     6541 caatcgtctg gtgctttaat tgctgcaaca gcgtggtctt cccacagccg attgcaccga
     6601 caaacatggc ccgtttcatc aaaccacgcc cctttcaatt agaaacgctt acatgtttaa
     6661 ttctaagtca aaataaatta aaagaaaggc tggttaatct ggtacgtttg tggtattaga
     6721 aaccgactat tattaaaaaa gtaatgtcca tttctccaca acggctatta gccatgtccg
     6781 accacagtaa aaaagcacca accatttttt caagaaaatg gttggtgcta agcatcttag
     6841 acgtgtattt agtctttcac taataccgtg acactttcca catgtggcgt ttgagggaac
     6901 tgatcgactg gttgcacggg accatcaacg tggtagccca actcagtaaa ccgggccaca
     6961 tcacgaacca acgtagccgg gttacagctc acgtaaacaa tcttcttagg cgccatctta
     7021 gcggcactgt caatcaagct ttcagccaag cctttacgcg gtggatctac cacaatgaca
     7081 tcgggcttaa taccggctgc ttgccactca gccatctggt cttcggcttt attcacagca
     7141 aaagtcacgt tactcaaatg attcttttgc gcattcacct tggcatcttc aatggcttct
     7201 gggacaattt cgactccata cacttgctta gcgtgcttag ctagcgccaa agaaatcgta
     7261 ccaatcccac agtaagcatc aatcacggtt tctgcaccag tcagtccagc cttatcaatc
     7321 gccatctggt aaagcttttc cgtctgttgg ggattaacct gatagaagga ccgtgctgaa
     7381 atagcaaagg tcaagcccat caacgtatcc tcgatagttg gcttaccgta aagcacccgc
     7441 gtcacattac ccataatcac attagttttc ttggcattga cgtttaacac aatgctcgtc
     7501 acttctggca aagcctgatg aatttgatcg actaattgcg cctgactagg aattttttgg
     7561 gttcggctaa tcaaaacaat catcatttcg tgactgtagt agccccgacg taccatgatg
     7621 tttcgaatga cgcccttatc actcacctca ttataggctg gaatctcaaa ctgacgcagt
     7681 aaatcccgga ccttgatgat ggctgcatca atcgctgggt cttggatata gaaatccgtc
     7741 agtgggatca gttcatgact gtgttgtcgg taaaagccgg tctccaattg tcccttaatc
     7801 atccgtaccg ggacttgagc cttatttcgg tattgggtag gattgtccat ccccatcgtt
     7861 ggtgcaacct caacgtcttg atgggactta ctgaaaagtt ccgcaatctg gtgttgcttg
     7921 aactttaatt gagcgggata agccaagtgt tgaagtggcg caatccccgt ttgccggtaa
     7981 gtcttatcca catccttcac ccgatcaggt gattcctgcg tccaagcaac cgcccgggca
     8041 aagccataat ggctctgtac tttggttact tgaatcgtta cttcttcacc tggtaaggtg
     8101 ttttcaataa acaaaggaaa atcttcaacc ttagccacgc ctaacccttg ataagttagg
     8161 tcggtaatag ttacatcaag ccgttcattt ttactaactg gtgctttact tttcataatt
     8221 acctcaattt cttagatgag aagagggatt ttgctactgt cgtgtcgtgc aaaatccctc
     8281 atcagtttca tttatctttc gtagtcgcgt ccgctgttgc cggcaactct tccacctgct
     8341 taacgaactt ctcttcagct tctaacagct ctgccgactc acttgttacc gccgaatccg
     8401 gaatagcatc caaattagca tacatttcaa tgtgttgccg tagattatgg aatttcatcg
     8461 gggcatcgcc accatattca ccgtccagat taatcatcat ccggtcctta actggccgcg
     8521 cgatcacctt actggttttc tcgtaaataa tgtgggggtc attgatatgt ttgccaccgt
     8581 tgagcactaa ccccatcaac cgcaaaattt ccggcatgct ggccgttttg acaataatca
     8641 tggtaaattt accatcatct agagccgcat ccggtacaat ttgttcaaat ccaccaattg
     8701 aattcgtcag tgccagtaaa aacatggacg cttgaccacg gaaatgccca ccatcgtagg
     8761 ttaagtccat ttcaatcggt ttgattcggg gcaacagttc ggcccctttt accaagtacg
     8821 ctagatagcc aaagatcgac ttcaaattcg atggaacatc ataggttaat tctgttagta
     8881 acccaccacc ggcaatatta atgaaataac tatcaccagc ctgaccaatg tccatcttaa
     8941 tcatttggtt ctttaaaacc actttagcgg ctgccagcgg atcttcccgt ggaatgtgca
     9001 gtgcccgggc ataatcgttc gtggtcccag ctggaataat ggccatcttt ggtcgatgtg
     9061 ccaagccagc tagtccgttc acaacttgat tgatggtccc gtcaccaccc gctgcaacaa
     9121 tgagttcaaa cccggcctta gcggcgcgag ttgcttcgtc gcgtgccgaa ttaggggctg
     9181 gcgttgtggc ataggcactt gtttcgtacc cggcctgttc aaacaccgct aaaatatcga
     9241 tcaagtcttt cttcaacgcc tcgcgccctg aagtcgggtt gtaaatcacc cgtgcccgtt
     9301 tacgcatgct gcgcctccat ttgttcttat tgctgtaatg ctgccatcaa cagcttgttg
     9361 acgacttgtg gattggcctg tccgtgagtc tgcttcataa tctgacccac taggaaaccg
     9421 accgcccgtt ttttcccgtt attgaagtct tcaatcgact gcgggttagc actcaagacg
     9481 tcatcgataa tcggttgtaa tttagctgga tcggatagtt gaaccagccc attggcctca
     9541 acaaaggcct tgggatcttc accctcggta atcgccttga agaccttctt ggccatcttg
     9601 ctagagatgg tcccgtcagt aatcaaattg atcataccag ccaaatgttc tggtgttagc
     9661 ttggttgcct gcaggtcgac ttgcttatca ttcaggtagg cattaacgtc cccttgcaag
     9721 taattggctg ccatcttcgg atcagctttc aacgcaactg ttgcgttaaa gaagtcagac
     9781 atttccttag tttgggtaat gaccatagcg tcataatccg tcaaacctaa ctcgttaacg
     9841 tatcgttcgc gccgcttccc tggcatttct ggcatggcgg catctagttc cttgatccag
     9901 tcatcactga tgttcagtgc tggcaggtca ggttctggga agtaccggta atcatcggca
     9961 ccagccttca cccgcatcag aatcgtttca ccggtctttt cgtcaaaccg acgcgtctct
    10021 tgttgaaccg cgccacctga cattaagact tgttgctgcc gtttttcttc gtattccaac
    10081 ccgcgttgga cgtaattgaa ggagttcagg ttctttaact cggtcttagt cccaaatttc
    10141 tgttgaccaa ctggccgaac agaaatgttg acatcaaccc gcatagaccc ttcttccatc
    10201 ttcacatcag aaatcccggt aaattgaatc cgttgccgca atgcttccaa ataagcgtag
    10261 gcttcagccg gtgacgcaat atctggcttc gacacaattt caatcaacgg tgtgccttgt
    10321 cggttcaaat cgacataaga gtaatcccgt tcatgggtgt tcttaccagc atcttcttcg
    10381 atatgcattt cagcaattcc gatttttttc ttgacgccat cgacgtcaat ttcaacccaa
    10441 ccatcgtgac caatgggctt gtcagattgc gtaatctggt aggccttcgg gttatcggga
    10501 taaaagtagt tctttcggtc aaaatgggtg tgttgttcaa ccgtcgcatg caacgctaag
    10561 gctgcaatga tcccgtcggc aacgacccct ttgttggtag ttggcaatac ccctgggtac
    10621 ccccagtcaa tcacgttcgt attggcgtta gggtcagccc cgtaggcaac tggtgatggg
    10681 ctaaagatct ttgaatgggt cttcaactca atgtggactt ccagcccaat cgtggtttca
    10741 aagttcatta gtgttgacct cctaacgtgg gaacttgtaa atgaaagtcc gtattttgct
    10801 caaaggcgta acccgcctta tacaacgtgc tttcatcaaa tggccggccg ataagttgca
    10861 taccaaccgg taagccttga ctgaagccag ctggcaagga caagcctggt agcccagcta
    10921 agttaactgg aatcgtcaag acatcattca tatacatcgt aattgggtct ttgatttcgt
    10981 cgccaatgcc aaaggctggt gttggcgcaa cggggcccat gataaagtca tgatccttca
    11041 agacagcctt gaaatcattc atgataaccg tccgcacctt ggctgctttc aagaagtaag
    11101 catcataaaa accagctgat aaggagaatg tccctaacat aatccggcgc ttaacttcgt
    11161 caccaaaacc ttcagaacgt gacttcacgt aaacatcttc caaattcttc acatcgtcgg
    11221 cccggtgacc ataccgaatc ccgtcaaacc gttgcaagtt agatgatgct tcagacgagc
    11281 caataatgta gtaagctgcg acaccatact tgttatgtgg taaggaaact tcatccaccg
    11341 tagcacccaa ttgccggtac gtatcagcag cagctaagat cgcctgttta acatcatcag
    11401 cgacaccatc tgccaaaaac tccttgggta agccaatgcg catccccttg acactcgttg
    11461 cgtcggttaa gtctgccgca aagtcaggga ctggttgtgt cgaactcgtc aaatcatgct
    11521 catcatgccc agcaatggcg cttagcatag tggcattatc cttcacgctg cgcgtcattg
    11581 ggccaatttg gtccagacta gaaccaaagg caattaagcc ccaccgagaa acgcggccat
    11641 aggttggctt taggccaaca atgccgttaa atgcggctgg ttgtcggata gaaccaccgg
    11701 tatctgagcc caaagcagcc aaaacttgac cggaagcaac ggccgccgcc gaaccacctg
    11761 aggacccacc aggaaccttg gtgtaatccc aagcattctt ggttgtctta aaagcagagt
    11821 tttcggttga accacccatg gcaaattcat ccaagttcgt tttcccaacc gtaatcatct
    11881 gagcctgggc taatttttca gtaaccgtgg catcatagac ggggttgaag ttcgctagca
    11941 ttttagaagc agcggtcgtc tttaggccct tcgtcacaat gttatctttt aatgccactg
    12001 gaattcctgc cagtggttga tcggttgcca caccttgttc gtcaatctta gtggcttgtt
    12061 ttaaagcggc atcttcgttc agcgttaaaa acgcatcgac ctgagcatcg gtcgtcttga
    12121 tattgtcaaa agttgcttgc gtcaattctc gggcgctgat ctttttagca accaaatcag
    12181 cgtggagact agcgagatct gttttaaagt aatccattta gtcgttatcc tcgctttcgt
    12241 caatgatggc cggcacttta ataaagcccc gggcagcttc tggcgcgttt ttcagtaatg
    12301 actggctttg accccagtta tcggcaacgt cttcgcgcat cacattgagt tggtccgtga
    12361 cactgctcgt ggcttcaacg ccgtcagtat cgacttcact cagcgtttca aacagaccga
    12421 taatgtcgtc aagttggggt gtaaaagcat ccaactgggc atccgtaaat tcaagttttg
    12481 ccaaactggc aacgtgttga acttgttctc gattgattcg attagccatc aattatccct
    12541 ctttctgatt tatccacaat tcagcgttta cccgcagttt ctgagaataa acatacactg
    12601 ccattctacc atatatccgc tgtacgccaa agattatgac aaaaagaatc ttgtctcacg
    12661 gtaaaatggc tacttattgg tgataacact gggttaagcg gccattaaca cggagatata
    12721 gacagcacct tattgggata agtacaacca tgagtagtag caggcaacgc caatactaac
    12781 gttcatcaat aattagatta ctatttctag caagtcagaa ttgttctagc tgaacttggc
    12841 acttaaccag attaccctgt cacaccacgg tagctcggcg ggaagcggca aatgggccca
    12901 gtaccgtcgt tatccttagc gcgtgttttt agcgtgctta ggataagacc gacctttaag
    12961 acaagtgccc tgcttggctt aaagtcgtgt ccggtacgtt ccagcccatt tgtcgcgacc
    13021 agggggcgga caatcaccac ccagtttaaa acacaggaat tttctaccgt cattatcttt
    13081 ttgcgcgtgt ttttttgcat atttaggata acaatctata aaccaaaaag gcgtgcacgc
    13141 cgtagcccac acaccttcga aattagattt aataactgtt aaagacgtga ctcgtgaatt
    13201 tctttgcccc actagaacgg gaaaggaaac tttgcacact atccgtcgat gagacggtaa
    13261 tgtcaatggg cacacttgat ggtaagtact tctgtgccgc cgtttgcaga tattgcgtga
    13321 agctaatgat ttctgtttgg ctgtagaatt gggtcgtaat attgacgtgc atcccagtca
    13381 atgtatttcc actgtaatgg gcttgcgccg tcacaccact caagttcggg aagaagtttt
    13441 ccacttgcga cttgaagtta gtaaaggagg tttcatcgtt actgttcggg ctactagacc
    13501 cactttcaat tgggaacacg tagttctttt cactcaaagc gttccactta gaaacggtcg
    13561 ttgcacttcc cttattctca gaataagcga tgaagttacc accgaccaga ctatcattgg
    13621 aggcctgccg atagattgca atcacgattg gcacgttctt taacgccgac ttcttacgga
    13681 gccgttttaa gaccgtatta gccgccttct tcgcgtaagc ttcaccctca gctttggtaa
    13741 tcttggtctc ataagtggca ccgtactggg tcttcttata ataatccacc gaattgacgg
    13801 caatcccaat cgttacacca cctaaagaaa gcttattatt cttttgggtc atatagtctt
    13861 gttcttccaa cgcttgaatg taaactggat ttcgcttcgt tggtgatgtt gagccgttac
    13921 tcttcggatt caatccagtt ggatttgatt tggtctttcg atccaaccaa ttttgaacag
    13981 ttgatgagct taaatactgg ccttcttgga aaacgtagct cttcgtagag aagactttct
    14041 tagaaacgcc taacatacca ttttcaaaac tcttcacgtt gtaggtattg ccagaatcct
    14101 gactattggt taccccacgc gacttgctcg tctggtaatg accactctta ataacccctt
    14161 catagtcacc atccgagctt tgccccgtca attgggtctt acttgatttg ctggtcccag
    14221 acgttccaga aatgctggaa ctgcttaaat tgccacacgc ggccaaaaat aatggcaccg
    14281 cggctaacgc aataaaggtt cgtaaccgtt tcacgacttg tttcctccta aagtcatcat
    14341 ttcgtttcat ccatggctgc ttgcaattgc gcttcattcc acacgggaac gtcgagtgac
    14401 tgagctttgg ctagcttact accggccgct tcaccagcaa tcagcagatc agtcttctta
    14461 gacacactgc cggtcactgt cgcaccgtgt tgttctaacc attcagttgc ttgtggacgc
    14521 gtcaactctt gtaactttcc cgttagaacc acccgcttac ccgtaaattc actcgtcgaa
    14581 ttggtggcgg gtgtcccact ggtataagtc atattgaccc caacggcttg tagtttagca
    14641 accagttcat ggacctgcgt attagcaaag taggtgacca cactatcagc aatgatgccc
    14701 cccactgtat caatcgcgga gatctgctca ctgtcagcgg ccattaaact cgccatatca
    14761 ccaaacgctg ctgccaatga tcgggcagct ttagctccca catggcgaat gcccaaacca
    14821 aatagcaaac gttctaatga attattgcga ctattatcaa tggctgtcaa gaggttttgg
    14881 gccgacttct ccccaaattt atctaaagtt aataattgat cggtcgttag ccgatacaaa
    14941 tcagccacat cctgaaccaa atttcgatcg aagagctggg ccacaatttg tggacccagt
    15001 cccgcaatgt tcatcgcatt tcgggaagca aagtggttca tcccttcggc caactgggct
    15061 ggacagcggg gattaataca gcgtaaggcc acttcgtcat ctaaatgaac caattcagct
    15121 ccacaggatg ggcaagtcgt cggaataaca taggctttcg cttcagccgg acgctttgcc
    15181 gccacatatt gcgaaatttc cgggataatg tcgcctgctt tatgcaacaa caccgtatcc
    15241 ccgatgcgaa tatccttagc aatcaaataa tctggattat gcaacgatgc gcgagccacc
    15301 gtactcccag ctaatgccac gggttccata atggccgtgg gcgtaaccac acccgttcgg
    15361 ccaatggtcc attcaatgtc taacacccgg gtctgcactt cttccggcgg aaatttatac
    15421 gcaattgccc accgcggaac tttcacggtc gctcccaggg aacgctgtaa gggcaaatca
    15481 tttgccttaa tcacaatacc atcaattccg taggccaatt ccgttcgctg tgcttgatac
    15541 gtttcgatat aagcagccac gtccgccata tcatgggcta ctcgataagt ggcattagtc
    15601 gtaaacccga gttcggccaa ttcatccaac aaaccacttt gcgtccgcgt ggtcagtggc
    15661 tcatagtcgg ccacgttata cataaacgtg gctaattgcc gatcagctgt cacacgcgta
    15721 tcgagttggc gtaggctccc ggccgccgca tttcgcggat tagcaaatgg ggcctgcccc
    15781 gctgcctctc gtcgctcatt taacgccaga aaggcggcct taggcatata acattcaccg
    15841 cgcacttcga ttgtcagtgg ccgactaagc gtttggggaa tagacttaat cgtcttcaga
    15901 ttagccgtaa tatcttctcc aatttgcccg ttgcctcggg ttgagccttg gacaaactta
    15961 ccattctcat acctcaacga aatcgctaag ccatcgattt ttaattcaca attataatca
    16021 aatggtgtat ccacgttgcc tcgtagtcgt tcatcaaatt ctgttagttc atcgagtgag
    16081 aaaacatcgc ctaatgacag cattggaata tcgtgagtga ccttaggcaa atcacttcgc
    16141 gaactaccgc caactcgctg cgttggtgag tctggcgtaa caatttctgg aaaggccgtt
    16201 tctaaggcca ccaatcgagc atacacgcga tcatacacgt cgtcttcgac agatggggca
    16261 tccgcttcgt agtactgctt cccccactct aacaattgtg ggcgtaagtc agcggcctcc
    16321 tcggcagcct gctccacggt tagcgtctta atgggcttat cagtcatcta attcctccca
    16381 aactttaaat gcttagtcta cgcgtttgat tggggcaaag gccgccaata aacgcttaat
    16441 cccttgttct gggaatgcaa tatcgagttc ggcatcttcg ccagtaccat taactttgac
    16501 cacggtaccc acgccccact ttttatgact ggctttatca ccaatcgtcc agctaacctt
    16561 accagcaccc gttccggttg gttcactcac ccgcccagtc ttaccagcgt atggcttcg
//
