LOCUS       gnlProkkaCFHMEBGC_1    21608 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CFHMEBGC_1.
ACCESSION   gnlProkkaCFHMEBGC_1
VERSION     gnlProkkaCFHMEBGC_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:14:03
            Original ID  :: gnl|Prokka|CFHMEBGC_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 163951
            Orig. end    :: 185559
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21608
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11608]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11608
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21608
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21608
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             2406..2606
                     /locus_tag="ctg1_147"
                     /transl_table=11
                     /translation="MIARKYLDNYSEIILNSLNLYSDNTTLRVSNSMTSDETLLKMEEL
                     MKDNPTEQELIKRLGKNFPQE"
     CDS             2687..3004
                     /locus_tag="ctg1_148"
                     /transl_table=11
                     /translation="MDEEYDDWLVNDDGKNNINDLIKETVALETTGKTGFFYLDKKRTQ
                     NIFKKSGYQLPSQLKNSGSNIIIRTIDDSVNKKSIILLKANNLSDGSVIGKIALQKQVK
                     R"
     CDS             3205..3642
                     /locus_tag="ctg1_149"
                     /transl_table=11
                     /translation="MSTRELLARLLKCEAGGEGENGMRAVASVIVNRTRVPNGEFARVS
                     KGGDFRAIMEQPNQFTCLKTTVGGQYNPQNVYNIRPDEIHYNIADWALAGNTDSSVGNS
                     IFYFNPFSDTCPTFFPSNNGVIYNRVGDHCFYSPTEAYSKT"
     CDS             3657..4364
                     /locus_tag="ctg1_150"
                     /transl_table=11
                     /translation="MDNSSNMAVNTTPMANQINPEHLYGLDKNKACLNNSCPSNTADIG
                     CYIPAIDEIMRHNQGAPSVAHPNMTEKVQKSNDNPSLEQAEIAYEEGGSTSEEQPENIN
                     KYSGSLQNIPFIKNLKKIDTSIPVLPATPATTASSGATVATPIRQNIGMSMSDYQYPFP
                     VTAENLRYHNGFMRTQIGRRITVDFLMGANTIVQKTGYLLGVAQDYILINEIDTNDITT
                     CDYYNIKFIRYYY"
     CDS             4617..5516
                     /locus_tag="ctg1_151"
                     /transl_table=11
                     /translation="MKFCKYCGAQLEDNAVCNCEKSRAAQAQAQQTNAQAQPQYQQPVQ
                     PQQPQYQNPVQQQYAQSQNPQTQQSPYAVNNTAPIGENAFVKALKNIPVVFTSFFKDSK
                     TVIKTAKAEKDIILGALFSAIFFIALILGNMFLMLSMSALDFPKTLLVSLVTAVLIGGL
                     YSVILFAYVKKYKTEENTAKAFIDSFITFSIESIPASIGWILAGLCALISVYMFLFFFV
                     IVMLYLVISLVNQVKANVPEAKNSALFTLILTLIVAVAFMIVFFIGAKLTMWSFNTSTF
                     ATSVLTSLIGGGSYPSWY"
     CDS             complement(5576..6676)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_152"
                     /sec_met_domain="PF04055 (E-value: 2.6e-19, bitscore: 66.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNSIGLYIHIPFCKHKCPYCDFFSGNADENDFDNYVIELKDKIK
                     YWSEKAKRDVATVYFGGGTPSVLGADRLCDILDFIKFNFNIQNNAEITVEVNPDSAKTI
                     DFEKMYACGFNRISMGMQTAVEDELRLLGRIHSIDDAKTSVERAKSAGFNNISLDLMMG
                     IPNQTIESLEKSISFCADCKVTHISSYILKIEENTPFYKVQNKLKLADDDMQAEMYLKA
                     VEMLDSLGYKQYEISNFAKQGYESRHNTNYWRCGEYIGIGPSAHSFFEGKRFFYSRSMD
                     DFNNNKLSFEGTGGDEEEFIMLSLRLKSGLNYSEFEEKFGYTLPSYIIKKAKEYEKYGY
                     TNVTDKSISFTPKGFLVSNSIISELI"
     CDS             6926..8512
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 109.2; E-value:
                     4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_153"
                     /transl_table=11
                     /translation="MSSFKEEISKRRTFAIISHPDAGKTTLTEKLLLYGGAINLAGSVK
                     GKRTAKHAVSDWMEIEKQRGISVTSSVLQFKYNGYCINILDTPGHEDFSEDTYRTLMAA
                     DSAVMVIDGSKGVEKQTIKLFKVCVMRNIPIITFINKMDRDAKNSFDLLEDIENVLGIH
                     TYPVNWPIGSGKEFKGVYDRNSKKILAFTANNGQKEVEKKELTLDDPALEDTIGYYHKQ
                     DLFDEIELLDGAGDEFDLEAVRNGQLTPVFFGSALTNFGVEPFLEQFLQLTTPPLPRET
                     VDEKVEPMSDFFSAFVFKIQANMNKAHRDRVAFMRICSGKFEKNMEVFHVQGNKKMRLS
                     QPQQIMAQEREIVDEAYAGDIIGVFDPGIFSIGDTICSPGHKVQFRGIPTFAPEHFALV
                     RQKDTMKRKQFIKGTSQIAQEGAIQIFQELDAGMEEVIVGVVGVLQFDVLKYRLQNEYN
                     CDIIMETLPYEFIRWIVNDDLDPKTLDLASDTKKIQDLKGNHLLLFTSYWSINWALEHN
                     KGLELAEFGTN"
     CDS             8536..9939
                     /NRPS_PKS="Domain: Aminotran_5 (55-217). E-value: 1.8e-13.
                     Score: 41.9. Matches aSDomain:
                     nrpspksdomains_ctg1_154_Aminotran_5.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_154"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.2e-10, bitscore:
                     37.3, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.3e-11, bitscore:
                     40.3, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 8.1e-08,
                     bitscore: 28.1, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYDKLKNYSKSGIYPFHMPGHKRTDITEEGIIPYNIDITEIHDF
                     DNLHSPNGVIYEIQKKAAKLYNAKNAFILINGSTGGILSAIRSMTNQGDKILMARNCHK
                     SVYNAAELFNLNVDYIFPDTDSRYNILTSVSPYDIEDKLTKHNDEIRLVIITSPTYEGV
                     VSDIKSISEICHKHGAKLLVDEAHGAHFPFSDSFPDEALNCGADAAVLSLHKTLPSLTQ
                     TALLITNDSELSEILAENLAVFETSSPSYILMSSIEKCLDFCENSKDKFKEYCCNLKTV
                     REKLKNLKYLKIYDKNDTDFDYDIGKIVISTANANISGTKLAEILRNNYQIETEMAYSD
                     YVIAMTSVCDTEKAFNMLSDALISIDSELSKGADTERVPLKNLYTGKNFNACELYKFNK
                     ETISFQNSEFRTSAEYIWAYPPGIPLIVPGEIISKELINYIEYLSACKVEIMSTKGGMT
                     DNISVVKKD"
     aSDomain        8701..9186
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_154_Aminotran_5.1"
                     /evalue="1.80E-13"
                     /label="ctg1_154_Aminotran_5.1"
                     /locus_tag="ctg1_154"
                     /protein_end="217"
                     /protein_start="55"
                     /score="41.9"
                     /tool="antismash"
                     /translation="YEIQKKAAKLYNAKNAFILINGSTGGILSAIRSMTNQGDKILMAR
                     NCHKSVYNAAELFNLNVDYIFPDTDSRYNILTSVSPYDIEDKLTKHNDEIRLVIITSPT
                     YEGVVSDIKSISEICHKHGAKLLVDEAHGAHFPFSDSFPDEALNCGADAAVLSLHKTL"
     CDS             10001..10153
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_155"
                     /sec_met_domain="TIGR03973 (E-value: 1.7e-25, bitscore:
                     84.9, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 8.1e-25, bitscore: 82.7,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIKTIETRDLKKSVKTGGCGECQTSCQSACKTSCGVANQQCEK
                     CMSEK"
     CDS             10235..11608
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_156"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 3.4e-30,
                     bitscore: 100.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.8e-13, bitscore: 46.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.9e-13, bitscore: 46.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1e-18, bitscore: 63.8,
                     seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKLNGYNIVLDVYSGSVHAVDDLAYDVIAMYKNATKEQIID
                     EMLSKYADNPEITKEEISDCIDDVKELEEQGKLFTEDKYENLAFDFKKRNTVIKALCLH
                     IAHTCNLNCEYCFASQGKYHGERALMSFEVGKRAIDFLIENSGSRVNLEVDFFGGEPLM
                     NFDVVKQIVAYARSIEKEHNKNFRFTLTTNGMLVDDDVIEFANKECHNVVLSLDGRKEV
                     HDHLRKTVNGKGSYDIIVPKFQEFVKKRGNKDYYVRGTYTHNNTDFTNDIFHMADLGFT
                     ELSMEPVVCAPDDPYALTYDDLPILFEQYEILAKEMLKREKEGRPLTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDEKYKLGDIFNGVSNTKIQDEFKLCNA
                     YARPDCKDCWARLYCSGGCAANAYHATGSITGIYEYGCELFRKRMECAIMMKVAEAEE"
     CDS             11674..12483
                     /locus_tag="ctg1_157"
                     /transl_table=11
                     /translation="MNEKIIMLGTGSAMVTDCYNTCFLLKSENDCLLVDAGGGNGILSA
                     IKKSGVAWNSIKTMFITHSHTDHILGAVWVIRQISALMNSGKYNGNFNIYCHDECVDSI
                     TAICNHTLAPKFLKNINTKIFINEVKDGEKQNAGSIRLTFFDIFSDKTKQFGFKAVFPS
                     GKVLACLGDEPFNEKCRNFVQNCDYLMCEAFCLYSQKDIFKPYEKFHSTALDAGKLAES
                     LFAKNLILYHAEDETLQTRKRTYTSEARTVFNGNIFVPDDFEVIDLK"
     CDS             complement(12475..14388)
                     /locus_tag="ctg1_158"
                     /transl_table=11
                     /translation="MFSTDKSSFNKKDVSDCDYKISLAGNPNVGKSTIFNELTGLRQHT
                     GNWTGKTVEFARGCCKIKDARFCITDLPGCYSLLSFSGEEAVTRECLIQNQNDCVVIVI
                     DCGVIERNLSFALQVLSVTKNAVLCLNLCDEAEKNGIKIDCDELSLNLGIPVVKTCATD
                     KKGLDELKKAIYNVCIGKIKCFRVERNFEGVDILSEKNYKQNIEKLSQIGNKISSECVK
                     YEKSELNACTRKLDKILTSKTTGIPIMLAMLGILFWITVVGANYPSEWLSNLFGFIKEK
                     LYILFDFLHAPDVVTGLLIDGVYTTLSWVVSVMLPPMAIFFPLFSLVEDSGYLPRIAFN
                     LDRYFSKCGAHGKQSLAMAMGLGCNACGVTGCRIIESPKERLIAILTNNFMPCNGRFPT
                     IIALLLMFFAGTAFTLSSSLEVAALLIGIIVFCVFITLVISKVLSVTILKGEQSGFVLE
                     LPPYRKPQILKTIVRSLLDRTLFVLGRAVAVAAPAGAIIWILANVHISDVSLLKYCTDF
                     LDPFGRFIGVDGVIIMAFILGFPANETVIPIIIMSYMASGTLVDYSSYDQLFQLLSMNG
                     WTITTAVCTIILCILHYPCSTTCLTIKKETGSLKWTLVSMALPTAMGIVLCMITAGVMR
                     LF"
     CDS             complement(14404..14640)
                     /locus_tag="ctg1_159"
                     /transl_table=11
                     /translation="MKEKCSLDKLPLGVTGIVYRVNCNENIKNRIFDFGIMENSSVIPL
                     FTSPFGDPSAYLVKNAVVALRNNDCKDIIVTPE"
     CDS             15123..17012
                     /locus_tag="ctg1_160"
                     /transl_table=11
                     /translation="MNKSFKKILSIVLSVMMILSLMTVSLSVSAVEDGKVRVIVRNDTY
                     SVENGAPWDGVLVDEWVSINNDTTMMSAVADALNNHGYTQEGAENNYISSINGLAAFDG
                     GTMSGWMGTLNDWFTNSGYASYTVADGTLESGDEIAIMYTSNGYGEDIGGTWANNDTTV
                     KSVEITGAELSGEFDPSVTDYTLTIDTPSADVNVVPTATNKNFQTRKYKNEYLPSDDSA
                     FYKRSQTVNVSDGDKIIIGCGDIAWPSMNTSEGGTVYTFTVKYAPSAADTVSNKIDEVA
                     KYLASQNTPTVSSVGGEWTVLGLARAGKITDEIADSYYQNAVKYVEEKGSAKLHNTKST
                     DNSRVILALTAIGKDVTDVASYNLLEPLADMDYVKKQGINGPVFALIALDTGDYEIPQT
                     DAANPTTREKLVQTILDAQVANGGWTFFGSTADPDMTGMAIQALAPYYSTNSDVKEAID
                     KALTAMSNAQNENGGFASWGSVNSESCAQVLVALTSLGIDPTNDERFIKNGNTLIDAMM
                     SFSAENGFGHTDTTYNQMATEQGFYAFVSFDRLVNGKTSLYNMTDRLAENYAVGDVNLD
                     NTVSVIDATLVQKQIVNLEQLSKVSLIKADVNHDGVIDVVDATEIQKIIVKLV"
     CDS             17039..17968
                     /locus_tag="ctg1_161"
                     /transl_table=11
                     /translation="MEKIKKFVKKNQILLIAVCVCIAALTVAFFAGGNRSENKVQTAST
                     ASSLSTTNADTETTSVSATEKTTQNPTDSTKSNKDKKDRNNSEDKKNSKDNSQNSNGSA
                     VEKSEKSEQSSNNSSSDKKKPSSSSNSSSKPNKKNDVQPTTQDKYKTDPVPSGKPKPVE
                     PEEQETKDTNLYCTFTITCSTILDNIDDLDPEKIELVPKDGIILKKQKVQFKEGESVYD
                     VLVKVCKDNNIHMESSWTPMYNSAYIEGINNLYEFDCGSLSGWMYKVNEWFPNYGCSRY
                     VLKNGDDVVWCYTCNLGYDVGGGYATGE"
     CDS             17971..18861
                     /locus_tag="ctg1_162"
                     /transl_table=11
                     /translation="MKDTFSNMHPFINFIFFALTIGFTMFIMNPVCLAVSFLCALVTAL
                     YLNGKKAVRLSLVFLLPMILLIVLINPVFNHEGMTILTYFPWDNPLTLESIVYGIASAF
                     LLSSTVLWFSSFNAVITSDKVVFLFGRIMPSLSLVISMALRFVPRFSAQMKLVRSAQHT
                     IGRDINEGTLFQRIRNAVKILSIMITWSLENAIETADSMKSRGHGLKGRTSYSLYKFDK
                     RDAFMLCTILFTGLVLMILLFTKAIKFRYYPSIKGDLFTVQSVVFYIFYTFLMLIPLSV
                     NIGEGIKWKHMQSKI"
     CDS             18834..21494
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 172.2; E-value:
                     2.4e-52)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_163"
                     /transl_table=11
                     /translation="METYAIKNLSFRYPETGIDVLKDITFSVNEGEFITVCGPSGCGKS
                     TLLRHLKPDLSPHGVLSGEIFFEEKPISDLSHREQSSKIGFVMQSPENQIVTDKVWHEL
                     AFGLESLGYDNNTIRKRVAETASFFGIQNYFEKSVLELSGGQKQILNLASIMAMQPSVL
                     ILDEPTSQLDPIAASEFLHCVSRINHELGTTVIITEHRLDEVLPLSDRVLVIENNGISA
                     FDSPQKVGKILKEKDSKTFLSMPAPMQIWQAVTENDNTDCPVTVPSGKKWLSEYAQNHK
                     MYELKPENILKHSDKEAVSLNDIWFRYEKSGTDVLKGLSLKIYQGEFAAILGGNGMGKS
                     TALSIICSLNKPYRGKVEISPLNKNSFDTLVAVLPQNPQTLFLKKTVLEDLYEVFDGRK
                     ISKEEKERRVTAAVKLCRLESLCNRHPYDLSGGEQQRAALAKILLIRPQILLLDEPTKG
                     LDAEFKIEFAQIIYDLNKAGITVLMVSHDVEFCAVYPSRCLMFFNGEVVSEGTPRTFFS
                     SNSFYSTSASRMSKGIIDNAVSSNDVIYACTGKNRNIQIDRNTPDIDLFKNDTENIPLQ
                     KNKAENKKLSVFKKIFGFFGAVLFILGLIINLEYIPNFSAKTLPTWFNWGIIGVSVALL
                     MIAFGTKSKRPIDLPRKSSKLSKRTVSMAIMVLLAIPVTIFVGMTYLQDQKYLFISLLV
                     MIECMIPFFLVFEGRHPKARELVIISVLCAIAVAGRLAFTMLPQFKPVVAIVIISGVAF
                     GGESGFLVGAVSMLVSNLMFGQGPWTPWQMFAAGIIGFIGGILFKKGLLGRTRTSLCIY
                     GFIATMVIYGGLMNLYSALTSHSAFNLNMLITFYVQGFPMDIVHAVSTVIFLFFGAEPM
                     LEKLNRIKVKYGLIE"
ORIGIN
        1 caacaggcgg attacctaaa agcttgtggg aaacatattc atcctttgca aatacactcg
       61 gaggaattat acttttaggt gtagaagaat acagggacaa atcacttcat cccgtaaatc
      121 ttcccgatcc ggatgaactt attgaggaat tttgggagat agcaaacgat attcaaaaag
      181 taagcacaaa cattctttca tatgatgatg tttatgtgca aaaaattgaa gaaaagcata
      241 ttatcgttat tacagttcca aaagcaaaaa gatttgaccg tcccgtgtat cttgacggca
      301 gcattcataa ttcatacaga agaaacggcg agggtgacta ccgttgcaca ctcgaccaaa
      361 ttaacgctat ggtgcgtgat tccgagatta aaacacagga tatgaatatc atcgaaagta
      421 tgactgcatc cgtatttaat accgattcac tccatagcta ccgaataaaa atgtcatctg
      481 ttaagccaaa caatcggctt caaaatttgt cggataaaga tttcttgcag gcaataggag
      541 caatcggaat atgggaagac cttttgtttc accctacagc cgcaggactt cttatgttcg
      601 gtaagtcaga gtgcatcaaa aaagaatatc cgtactattg tcttgaatat aaggaaacaa
      661 cacaagatga taaacacaca attatttcat cagatttaaa ttctgactgt gaaaaccttt
      721 atgatttctt tataaaggtc tttgaaaaaa tttcatacga tataaaactg acagcaaaca
      781 taaaatcaga cattacaccg attacaactg ccttacagga agctcttgca aactgcctta
      841 taaatgccga ttattatggt tcaaacggtg ttgttattat gaaagatgat gaaagcatta
      901 caatatccaa tccaggcgga tttagagttg aactcgacgc cgcaagagcg ggtggtatat
      961 ccgaccccag aaacacggca attatgcgta tgtttaattt gataggaatc ggcagtaacg
     1021 acggcttcgg tatttctaat attttctccg tttggaaaag tcacaaactt gttctgccgg
     1081 tcattgaaga aagtttcaac cccgaaagca tcaccctaaa gctttcgttt gttcccgaaa
     1141 gtaaatcaac taatactcaa attttacaaa atcgtcccga tattgaaaca gacagacagg
     1201 atgccgtaat ttcatacatt actgacaaca tcacggtaac ttcaaaagaa atttccgaac
     1261 ttctcggaat aagtcataaa aaatcgaagc aacttcttca caaacttatg gcaaaggatt
     1321 ttgttataat caaaaacgga aaatacaccc taaaagcata gaaggaacag aatcaaattt
     1381 cggaacagca atccgcataa gcgttactta taattgctag gttgcttatt tttgcaaaag
     1441 gaaaaccgtc tgctgtaaaa aaatccaaaa gataaatttg cctatatctg ccttttatgt
     1501 gccgcaacag gactgttcat gactctgctg ttacaaagtc ttgcaagacg attccgcagg
     1561 tgcagttgtg ccgatttata atttgagtat ggttgtttca ataatctttt cgtacatgat
     1621 tttcaaaaaa gtgtccccaa aatcaaacat aagtattcat ataataatcg cagacactta
     1681 tttatgcttt tacggattaa atttaaaatt tacaaatttg tgtaattttg cttgacaatc
     1741 acacaaaaaa caagtacaat aaacaaggtt aatcaccaat attcggagac gtatcgaagt
     1801 ggtcataacg gacatgactc gaaatcatga tgccccctga gggacgaggg ttcgaatccc
     1861 tccgtctccg ccataaaaaa caccgtagtt ctgttagaat tacggtgttt tttgctcaat
     1921 atcaatagtc ggggggtaat ccgaaaaatt cgagtaattc gagtatatga tatttataat
     1981 atgatattta taagtggcta attattttca cgccctgtat ttattgataa gtataatcta
     2041 aaaatcctgt tatgattgca gtcccacttc tttttgatat tcattacttt ctaacttggt
     2101 aatattctga tttgtaataa atcctaaata cggtggaaag ttctctgaag tcttaacggc
     2161 agaagaatgg cggaaattca cgcacgctat gtcaacagga cttgattcgg gattaagaat
     2221 aaatgataac tcaattcttg ttgagtgtga agtggactca aagtatcaat acaaattagt
     2281 tatctacgac aatacttttg acgataatcc tttagaaaag gtttatgcaa tccgaaatat
     2341 agattataat ataaccgatg gcaacaaaat cgcaaatttt ataattaaat tagaggaaaa
     2401 caattatgat agcaagaaag tatttagaca attactcaga gattatacta aacagtttga
     2461 acttatactc ggataataca acattaagag taagcaattc aatgacatcg gacgaaactc
     2521 tgttaaaaat ggaagagtta atgaaggaca atccaacaga gcaggagtta atcaagagat
     2581 tgggcaagaa ctttccgcag gagtaaaaga aaaattctcg cttgatgaag attatgattt
     2641 tacagatgaa aaagccagtg taatacacga tacgctgaaa tttttaatgg acgaagaata
     2701 cgatgattgg cttgtgaacg atgacggcaa aaacaacatc aatgatttaa tcaaagaaac
     2761 tgttgcttta gaaacaacag ggaaaacagg atttttttat ttagacaaaa aaagaaccca
     2821 gaatattttt aagaagtcag ggtaccaatt acccagccaa cttaaaaatt cgggttccaa
     2881 tatcattata cgcactattg atgatagtgt caataaaaaa tcaataatat tactcaaagc
     2941 aaacaattta tctgatggtt cggtgattgg caaaatagcc ctgcaaaagc aagtaaagcg
     3001 gtagacagca acagctaatc tgaataaatg ttgtagttgg catctcaaaa gattatcgaa
     3061 caccgtctga tttgcttcta taaaacagaa ttttctgtct gcgtgaataa cacatttatc
     3121 acaagctttt tctttgtaac aacaagttaa tttatgcata aaatatcatt gaataaaaat
     3181 aacggttggt gaaaaaaggt ggcattgagt acaagagaat tgcttgcaag gcttttaaaa
     3241 tgtgaggcag gtggggaagg tgaaaacgga atgcgtgcag ttgcgtcggt aattgtaaac
     3301 cgaacccgtg ttccaaacgg ggaatttgca agagtcagca agggtggaga tttccgtgcc
     3361 ataatggaac aaccaaatca atttacctgt cttaaaacaa ctgtcggagg gcaatataat
     3421 cctcagaatg tttacaatat acgtcctgac gaaattcact ataacattgc cgattgggca
     3481 ttggcgggca ataccgattc atctgtcgga aattcaattt tctattttaa tccattttca
     3541 gatacctgcc caacattttt tccgtcaaac aacggagtaa tttacaacag ggtaggggat
     3601 cattgctttt attcgcctac cgaggcttat tccaaaacat aaaggagcat agcttaatgg
     3661 ataattcttc aaatatggca gttaatacaa ctcctatggc aaatcagatt aatcccgaac
     3721 atctttacgg acttgacaaa aacaaagcct gcctcaataa ttcttgtccg tcaaacacag
     3781 cggatatcgg atgttatatt cctgcgattg acgaaattat gcgacacaat cagggtgcac
     3841 cgtctgttgc acaccccaat atgacagaaa aagttcaaaa atcaaatgac aatccctcgc
     3901 ttgaacaggc agaaatagca tatgaagagg gcggaagtac atcagaagaa caacctgaaa
     3961 atataaataa atacagcgga agtcttcaaa atataccgtt cattaagaac ttaaaaaaaa
     4021 tagatacatc tatacctgtt ttgcctgcaa cccctgctac aacggcgagc tccggagcca
     4081 ccgttgcaac gccgataagg cagaatattg gaatgtcgat gagtgattat caatatccgt
     4141 ttcctgtaac agccgaaaat ctgagatatc acaacggctt tatgcgaaca caaatcggaa
     4201 gacgaatcac cgttgatttt ctcatgggag caaacacaat tgttcagaaa acaggctatc
     4261 ttttaggtgt tgctcaggat tatatcctta taaatgagat tgacaccaac gacatcacaa
     4321 cctgtgatta ctacaatata aaatttataa ggtattatta ctaaaccaca gcggcaaaag
     4381 ctttaaacat tagtttttgc cgctgtttta ttgtcatttt tagtgaaatg tacattattt
     4441 cataatttta acatataatt ttctgtagta ttaaaaaatt aaaaaattgt aagaaatatt
     4501 gaattattgc tgtaatttgt gatacaatgt gagcgttgat gttatcactt ctcaataaac
     4561 aaacaacagg tagctataag acctgttaca tattatttta tcttggagga atcaccatga
     4621 aattctgtaa atattgcgga gcacagcttg aagacaatgc tgtttgcaac tgcgaaaagt
     4681 caagagccgc tcaagcacag gctcagcaga caaatgcaca ggcacagcct cagtatcagc
     4741 agcctgttca accacaacag ccacagtatc agaaccctgt tcagcaacag tatgcacagt
     4801 cgcaaaaccc tcagacacag cagtcgcctt atgccgtaaa taacacagca cccattgggg
     4861 aaaatgcttt tgttaaggct ttaaagaaca ttcctgttgt gttcacttca ttctttaagg
     4921 actccaaaac tgttatcaaa acagcaaagg ctgaaaagga catcattctc ggcgctcttt
     4981 tctcggcaat tttctttatt gcactcattc ttggcaatat gtttcttatg ctttctatga
     5041 gcgcacttga ttttccgaaa acacttcttg taagtcttgt tactgctgtc cttatcggcg
     5101 gcctctattc tgttattctc tttgcatatg taaagaaata caaaaccgaa gaaaacacag
     5161 ccaaagcatt tattgattca ttcatcacat tttcaattga atctattccg gcatcaatcg
     5221 gttggatttt ggcaggtctt tgcgcattaa tcagcgtata tatgttcctg ttcttcttcg
     5281 taatcgttat gctttacctt gttatttcac ttgtaaatca ggtaaaagct aatgttcccg
     5341 aagcaaagaa ctctgcatta ttcactttaa ttctcacgct catcgttgcc gttgcattta
     5401 tgattgtatt cttcatcggc gcaaaactta ctatgtggtc atttaacaca agtacatttg
     5461 caacaagtgt tcttacatcg cttatcggcg gcggttcata cccttcatgg tattaatctg
     5521 acatacaaat tcataacata aaattaacgc tccgaattta ttctcggagc gttttttata
     5581 tcagttcact gattattgaa tttgaaacaa gaaaaccttt cggtgtaaag ctgatagact
     5641 tgtccgtaac atttgtatag ccgtattttt catactcttt agcttttttg ataatgtaag
     5701 aggggagggt gtatccgaat ttttcctcaa attcagaata attaagaccg ctttttaacc
     5761 tgagagagag cataataaat tcttcctcat ctccgcccgt accttcaaaa gacagcttat
     5821 tgttattaaa atcatccatg cttctcgaat aaaagaacct tttgccctca aaaaatgagt
     5881 gtgcagacgg acctatgccg atatattcac cacatctcca gtaattggta ttatgtcggc
     5941 tttcataacc ctgttttgca aaattagaaa tttcatattg cttgtatccg agagaatcaa
     6001 gcatttcaac agctttcaga tacatttcag cctgcatatc atcatcggca agcttaagtt
     6061 tattttgcac cttataaaac ggagtattct cctcgatttt caaaatgtat gatgaaatat
     6121 gagtaacttt gcaatcggca cagaaactga ttgatttttc aaggctttca attgtctgat
     6181 taggaattcc catcatcaaa tcaagtgaaa tattattaaa tcccgcactt ttagcccttt
     6241 caacagaagt ctttgcatca tcaatgctgt gaattctccc aagcagcctt aattcatctt
     6301 caacagcagt ctgcataccc attgaaatgc gattgaatcc gcaggcatac attttttcaa
     6361 aatcaatagt tttggcggag tcgggattga cttcaaccgt aatctcggca ttattttgaa
     6421 tattaaaatt gaacttgata aaatcaagaa tatcacaaag tctgtctgca cccaaaacac
     6481 tcggcgtacc gccgccgaaa tatacggttg caacatctct tttggctttt tcagaccagt
     6541 attttatttt atcttttaat tcaatcacat aattatcaaa atcgttttca tctgcattgc
     6601 cgctgaaaaa atcgcaatac ggacatttgt gcttacaaaa cggtatgtga atgtaaagac
     6661 cgatagaatt actcataaaa aacctcataa atgattttga ggcagaaaca caagtttctg
     6721 cctcgatttg gaaggtatat gaaaaaatag gaaaaatcac attaaatcct tctgtaccaa
     6781 tatattacaa tatatttaca aatttgtcaa gtttttgtag caattatttt tctcacattt
     6841 tcttcattct ttattgacat ataccatcca aaaatagtaa aatataaaat tgtggatata
     6901 cttaacctcc gaagggaaga aagatatgag ttcatttaaa gaagaaatca gcaagcgcag
     6961 aacctttgcg attatttcgc atcctgatgc gggtaaaaca acacttacgg aaaaactctt
     7021 gctctacggc ggagcaatta accttgcagg ttcggtaaaa ggcaaaagaa ccgcaaagca
     7081 tgctgtgtcc gactggatgg aaattgaaaa acagcgtggt atttctgtta catcatcggt
     7141 tttgcagttt aaatataacg gttattgcat aaatattctt gatacaccgg gacatgagga
     7201 tttctcggaa gatacctacc gtacacttat ggcggcagac tctgccgtaa tggtaattga
     7261 cggttcaaag ggtgttgaga aacagactat caaacttttt aaggtctgtg taatgcgtaa
     7321 tattcctatc attacattca tcaacaagat ggacagagat gcaaaaaatt cttttgacct
     7381 tcttgaagac attgaaaatg ttctcggaat tcacacctat cccgtaaact ggccaatcgg
     7441 ttcaggtaag gaattcaagg gtgtgtatga cagaaattct aagaaaatcc ttgctttcac
     7501 cgctaataac ggtcagaaag aagttgaaaa gaaagaactt acgcttgacg atcctgccct
     7561 tgaagataca ataggctact atcataagca ggatttgttt gatgaaatag aacttcttga
     7621 cggtgcaggc gatgaatttg accttgaagc agtccgcaac ggtcagctta ctcctgtatt
     7681 cttcggttcg gctcttacaa actttggtgt tgaaccattc cttgaacagt tcttacagct
     7741 cacaactcca cctctgccaa gagaaacagt tgatgaaaag gttgagccta tgtcagactt
     7801 tttctctgca tttgttttca aaattcaggc aaacatgaat aaggctcacc gtgacagagt
     7861 tgcatttatg cgcatctgca gcggcaagtt tgaaaagaat atggaagtgt tccatgttca
     7921 gggcaacaaa aaaatgcgtc tttcacagcc acagcagatt atggctcagg aaagagaaat
     7981 tgttgacgag gcatatgcgg gcgacatcat cggtgtgttt gatccgggca ttttctcaat
     8041 cggtgacaca atctgttcac cgggacacaa ggtacaattc aggggaattc ctacatttgc
     8101 tccagaacac tttgcacttg tccgtcagaa agacacaatg aagcgcaaac agttcatcaa
     8161 gggtacaagt cagattgcac aggaaggtgc aatccagatt ttccaggagc ttgacgcagg
     8221 tatggaggaa gttatcgttg gcgttgtagg cgtacttcag tttgatgttc ttaaatacag
     8281 acttcaaaac gagtacaact gtgatatcat tatggaaaca ctcccatatg aatttatccg
     8341 ttggattgta aacgatgatc ttgatccgaa aactctcgac cttgcgtcgg atactaagaa
     8401 aattcaggat cttaaaggca atcatctttt gctctttaca agctactgga gcataaactg
     8461 ggcgcttgaa cacaacaagg gacttgaact cgctgagttc ggtacaaact aaatatttaa
     8521 aatatcggag gatatatgct gtacgacaag cttaaaaatt attcaaaaag cggcatatat
     8581 ccttttcata tgcccggaca caaaagaacg gacattacag aagagggtat aataccgtat
     8641 aatatcgaca taaccgaaat tcatgatttt gacaatctac attcaccaaa cggagttatt
     8701 tacgaaattc agaaaaaggc tgcaaagctt tacaatgcaa aaaatgcttt cattctgatt
     8761 aacggttcaa caggcggaat actttcagca attcgctcaa tgacaaatca aggcgacaag
     8821 atcttaatgg ctcgtaactg ccacaaatct gtatataatg cagcagaact gtttaatctc
     8881 aatgtcgatt acatttttcc cgatacagac agcagataca atattcttac atcggtttca
     8941 ccttacgata tagaagataa acttacaaaa cacaatgatg aaatcagact tgtaatcata
     9001 acttcgccta catatgaagg agttgtttcg gatataaagt caatctccga aatctgtcac
     9061 aaacacggag caaaattact tgttgacgaa gctcacggag cgcattttcc gttttcggac
     9121 agttttcccg atgaagcact taactgcggt gcagacgccg cagtattgag tctgcacaaa
     9181 actttgccgt cattaactca aactgcattg ctcataacaa atgacagcga gctttctgaa
     9241 attcttgctg aaaatttggc tgtatttgaa acaagcagtc cgtcatatat tttaatgagt
     9301 tcaattgaaa aatgtcttga tttctgcgaa aacagcaaag ataaattcaa ggaatattgt
     9361 tgcaatctta aaacggtcag agaaaaactt aaaaatctaa aatatctgaa aatttatgat
     9421 aaaaacgata ctgattttga ttatgatatc ggcaaaattg taatttcaac agcgaacgca
     9481 aatatttcgg gaacaaagct tgccgaaata ctgcgaaata attatcagat tgaaaccgaa
     9541 atggcatatt cggactatgt aattgccatg acatctgttt gtgacactga aaaagctttt
     9601 aatatgcttt cagatgctct gatttcaatt gacagcgaac tttcaaaagg agccgacacc
     9661 gagcgtgttc cgttaaaaaa tctctacaca ggcaaaaatt tcaacgcctg cgagttgtac
     9721 aaattcaaca aagaaactat ttcgtttcaa aattcggaat tcagaacttc tgccgagtac
     9781 atctgggcat atccacccgg aattcccctc atcgtacccg gtgaaattat aagcaaggaa
     9841 cttataaatt acattgaata tctttcagcc tgcaaggttg agattatgtc aacaaaaggc
     9901 ggtatgacgg acaacataag cgtagttaaa aaagattgac aaatcaatgg ctgtgtgata
     9961 atattaaact aacaaaatct aacaaggagt ttgatttatt atgaagagaa ttaaaactat
    10021 cgaaactcgt gacctcaaga agagcgttaa gacaggcggt tgcggcgagt gccagacttc
    10081 atgtcagtca gcgtgtaaga catcttgcgg cgttgctaac cagcagtgcg aaaagtgcat
    10141 gagcgagaaa taattctatt ttaatttgat tattaaggat tatcgccgtt ttcccaaagg
    10201 gttaacggct ttccttttgt ctaacggaga tattatgatt catcagtata aacttaacgg
    10261 atacaacata gttcttgatg tttacagcgg cagtgtacac gcagtcgatg accttgctta
    10321 tgatgttatt gcaatgtaca aaaacgcaac aaaagaacag ataatcgacg aaatgctttc
    10381 aaaatatgca gacaatcctg agattacaaa agaagaaatc tccgactgca ttgatgatgt
    10441 aaaagagctt gaggaacaag gaaagctctt tacagaagac aagtacgaaa accttgcatt
    10501 tgactttaaa aagagaaaca cagtaatcaa agcactttgt ctgcacattg ctcacacctg
    10561 taaccttaac tgcgaatact gctttgcaag tcagggcaaa taccacggcg agagagcgct
    10621 gatgagcttt gaagtgggca agagagcaat tgactttctc attgaaaatt caggcagcag
    10681 agtaaacctt gaggttgact tctttggcgg agaacctctt atgaactttg atgttgtaaa
    10741 gcagattgtt gcctatgcaa gaagcattga aaaggaacac aacaaaaact tccgttttac
    10801 acttacaaca aacggtatgc ttgttgatga cgatgtaatt gaatttgcaa acaaagaatg
    10861 tcacaatgta gttctcagcc ttgacggcag aaaagaagtg catgaccatc ttcgcaaaac
    10921 tgtaaacggc aagggcagtt atgatattat cgttccgaaa tttcaggaat ttgtcaaaaa
    10981 aagaggcaac aaggattact atgtaagagg cacttataca cataataaca cagacttcac
    11041 aaacgatatt ttccatatgg cggatttggg atttacagag ctttcaatgg agccggttgt
    11101 atgtgctccc gatgacccat atgcacttac atatgacgat ttgcctatcc tttttgaaca
    11161 gtacgagatt cttgcaaagg aaatgctcaa gcgtgaaaaa gagggcagac cgctcacctt
    11221 ctatcactat atgattgacc ttacaggcgg tccgtgcatt tataagagaa tctcgggttg
    11281 cggttcgggt acagaatata tggctgtaac accttggggc gacctctatc cctgtcatca
    11341 atttgtaggc gatgaaaagt acaagctcgg cgatatcttt aacggtgttt caaacacgaa
    11401 aattcaggac gaatttaagc tttgtaacgc atacgcccgt cccgactgca aagactgctg
    11461 ggcaagactt tattgcagcg gcggttgtgc cgcaaacgct tatcatgcaa caggctcaat
    11521 cacaggtatt tacgaatacg gctgtgagct cttcagaaaa agaatggaat gtgccattat
    11581 gatgaaggtt gcagaagcgg aagaataaaa ttacaataaa attttcaggc agatacattt
    11641 ttcttgtatc tgcctgtatt ttcgaggtgc tgtatgaacg aaaaaattat tatgctcggc
    11701 acaggaagtg cgatggttac cgactgttat aatacctgtt ttcttctgaa atccgaaaac
    11761 gactgtcttc ttgttgacgc aggcggcgga aacgggattt tatccgcaat taagaaatcc
    11821 ggagtagctt ggaacagcat aaaaacaatg tttattactc attctcacac cgaccatatt
    11881 ttaggtgccg tgtgggtaat aaggcaaata agcgctctta tgaattcagg caaatataac
    11941 ggtaatttta atatttactg ccacgatgaa tgtgttgatt caatcacggc aatttgcaac
    12001 cacacacttg caccgaaatt tctcaaaaat atcaatacaa aaattttcat caatgaagta
    12061 aaagacggtg aaaagcaaaa tgccggcagt atccgactca ctttctttga tatattttca
    12121 gacaaaacaa agcaattcgg attcaaggct gtttttccgt caggaaaagt tctcgcctgt
    12181 ctcggtgatg aaccgttcaa tgaaaaatgc agaaattttg ttcaaaactg tgattatctt
    12241 atgtgtgaag ctttttgtct ttacagtcaa aaagatattt ttaaacctta cgaaaaattc
    12301 cacagcacag cacttgatgc cggaaaactt gcagagagtc tttttgcaaa aaatcttatc
    12361 ctgtatcacg ccgaggacga aacacttcaa acacgcaaaa gaacatatac ttctgaggca
    12421 agaacagttt ttaacggaaa tatatttgtt cccgatgatt ttgaagttat tgacttaaaa
    12481 taatctcata acacctgctg taatcataca aagcacaatt cccattgcag tgggcaaagc
    12541 catagaaaca agcgtccatt taaggctgcc tgtttctttt tttattgtca gacaggttgt
    12601 tgaacacgga taatgaagaa tgcaaagaat aatcgtacat acagccgttg taatcgtcca
    12661 gccgttcata ctgagaagtt gaaacagctg atcgtagctt gaataatcaa caagagtacc
    12721 gcttgccata tatgacataa ttataatcgg aataacggtt tcattcgcag gaaatccaag
    12781 tataaatgcc attattataa cgccgtcaac cccgataaat ctgccgaacg gatctaaaaa
    12841 atcagtacaa tattttaaaa gtgaaacatc gcttatatgc acatttgcaa gaatccagat
    12901 tatcgcacct gccggagcgg caaccgcaac agcccttcct aaaacaaata aagttctgtc
    12961 caacagcgaa cggacaatag tttttaaaat ctgcggcttt ctgtacggcg gaagttcaag
    13021 cacaaatccg gactgttcgc ctttcaatat tgtgactgaa agtaccttag atataacaag
    13081 tgttataaaa acacagaaaa ctattattcc aatcaacaat gccgctacct caagcgaact
    13141 gctcagcgta aatgccgtac ctgcaaagaa catgagcagt aatgcaatta ttgtgggaaa
    13201 ccgtccgtta cacggcataa aattatttgt aagaattgca atcagtcgtt cctttggcga
    13261 ctcgatgatt ctgcatcccg taactccgca ggcattacag ccaagcccca ttgccatagc
    13321 aagactttgc tttccgtgag caccgcactt tgaaaaatac ctatcaagat taaatgcaat
    13381 tctcggcaga tatcccgaat cctcaacaag cgaaaataac ggaaagaata tagccatagg
    13441 aggcagcatt acagatacca cccatgacag agttgtataa actccgtcaa tcaaaagtcc
    13501 cgttacaaca tcgggagcgt gtaagaaatc aaaaagaata tacagcttct cttttataaa
    13561 gccaaacaaa ttgcttaacc attcgctcgg ataatttgca ccgacaactg ttatccagaa
    13621 caatatacca agcattgcaa gcataatcgg tattcccgtg gttttgcttg taagtatttt
    13681 atcaagcttt cttgtacaag catttaactc tgatttttca tattttacgc attcacttga
    13741 aattttgtta ccaatttgcg aaagcttttc aatattctgt ttgtagtttt tttcggatag
    13801 tatatcaacg ccttcaaaat ttctttctac cctaaaacat tttatctttc cgatgcatac
    13861 attatagatc gcttttttca attcatccag accttttttg tctgttgcac aggttttcac
    13921 aacaggtatt ccgaggttta gcgataactc atcgcagtcg atttttatac catttttttc
    13981 agcctcatca caaagattaa gacaaagaac agcattcttt gtgacagata acacctgcaa
    14041 tgcaaatgaa agatttcttt caataactcc gcagtcaata actattacaa cgcagtcatt
    14101 ttggttttgt ataagacact cccttgttac cgcctcttcg cccgaaaatg aaagcaggga
    14161 atagcatccg ggtaagtcag taatacaaaa tcttgcgtct ttgattttgc aacaacctct
    14221 ggcaaactca actgttttac ccgtccagtt tcccgtgtgc tgtcttaatc ccgtcagttc
    14281 gttaaaaatt gtactcttgc cgacattagg attaccggca agagaaattt tgtaatcgca
    14341 atccgagaca tcctttttat taaaagatga tttatccgta gaaaacaata aaaaagcctc
    14401 cttttattca ggagtaacaa tgatatcttt gcaatcgtta tttctcagtg ccacaacggc
    14461 atttttaaca agatacgcag acggatcacc gaacggactt gtaaacaagg ggataacaga
    14521 actgttctcc ataataccga aatcaaatat tctgtttttg atattttcat tacagttcac
    14581 acgatagaca atccccgtaa ctccaagcgg taacttgtca agcgaacatt tttctttcat
    14641 ctgattcacc gatttcaact ttttattaac agcatattca attcatacaa ctgagttaca
    14701 caaaaagccg gccatacaaa aagccggcca taaactaaac ttatatcgta cctgaataaa
    14761 ctctgatatc agaaaaattt taaggaattg acacgactat aaacaggtgt tataattaaa
    14821 tgcagatttc aaatgtatat aatttaatat gggtttacgg ttcaaaatgc atcttgcaga
    14881 gtagataaca gagaattcgg tgagaatccg aagcaacagt cattactgta tttggcattg
    14941 ccataagtca ggtcgctgtc cgtatgcctc ggattttgca aatcttggac agggaagagg
    15001 tgcaaccgac catatctgta cagacttttg gtctgtatgg ttttgtttgt tgtgccttcc
    15061 aaaaacggaa ggctttttat tttgcctttc gatatacata atacaatatg gaggaaaaca
    15121 ctatgaacaa atcttttaaa aaaatcctct caattgtact ttctgtaatg atgattttgt
    15181 cacttatgac ggtttcactt tcagtaagcg cagttgaaga cggaaaagta agagtaattg
    15241 tcagaaatga tacgtactcg gtagaaaacg gcgctccgtg ggacggcgtt ctcgttgatg
    15301 agtgggtaag cattaataat gacactacta tgatgtcagc ggttgctgat gcactcaaca
    15361 atcacggcta cacacaggaa ggtgctgaga acaattacat ctcgtcaatt aacggtcttg
    15421 ctgcatttga cggcggtaca atgagcggtt ggatgggaac tctcaatgac tggttcacaa
    15481 attcaggtta tgcatcctat acagtagcag acggcacact tgagagcggt gacgaaatcg
    15541 ctattatgta tacttcaaac ggttacggcg aggatatcgg cggtacatgg gcaaataacg
    15601 atacaactgt taaatcggtt gaaatcacag gtgccgagct ttcaggcgaa tttgatccgt
    15661 cagttacaga ctacacactc acaatcgaca caccgtcagc tgatgtaaat gtagttccta
    15721 ctgcaactaa caaaaacttc cagacaagaa aatataagaa tgaatatctt ccttctgacg
    15781 acagtgcgtt ttacaagaga agtcagactg ttaatgtttc tgacggtgac aaaattatca
    15841 taggctgcgg tgatattgca tggccgtcaa tgaacacaag tgaaggcggt actgtatata
    15901 cattcacagt gaaatatgct ccttccgcag ctgacacagt ttcaaacaag attgacgagg
    15961 ttgcaaaata tcttgcatca caaaacacac ccacagtttc ttcggtaggc ggtgagtgga
    16021 cagtcctcgg tcttgcaaga gcaggtaaaa tcacagacga aattgcagac agttactatc
    16081 agaatgcagt taagtatgtt gaagaaaagg gttctgcaaa gcttcacaat actaaatcaa
    16141 cagacaattc aagagtaatc cttgcactta cggcaatcgg taaggatgtt acggatgttg
    16201 catcatataa ccttcttgaa ccgcttgcag atatggatta tgttaagaag cagggtatca
    16261 acggtcctgt atttgcactc attgcacttg atacgggcga ttatgaaatt ccgcagactg
    16321 acgccgcaaa tcccacaaca agagaaaaac tcgtacagac aattcttgat gcacaggtag
    16381 caaacggtgg ctggacattt ttcggctcaa ctgcagatcc tgatatgaca ggtatggcaa
    16441 ttcaggcact tgctccttac tactcaacaa acagcgatgt taaagaggca attgataaag
    16501 cactcacagc aatgtcaaac gcacagaatg aaaacggcgg atttgcatca tggggttctg
    16561 taaacagcga aagctgtgca caggtactcg ttgcacttac aagccttgga attgatccta
    16621 caaatgatga aagattcatc aaaaacggca acacactcat cgatgctatg atgagtttct
    16681 ccgctgaaaa cggattcggt catacagaca caacatacaa tcagatggct acagaacagg
    16741 gtttctatgc ttttgtttca tttgaccgtc ttgtaaacgg caaaacttca ctctacaata
    16801 tgactgaccg acttgcagaa aattatgccg taggtgatgt taatcttgac aacacagttt
    16861 ctgtaattga cgcaacactt gttcagaagc agattgtaaa ccttgaacag ctttcaaagg
    16921 tttcacttat caaagctgat gtaaatcatg acggtgttat cgatgttgtt gatgcaacag
    16981 aaattcagaa aatcatcgtt aagctcgttt gattaaagtt cacaagtaaa aattggttat
    17041 ggaaaagata aaaaagtttg ttaaaaaaaa tcaaatactt ttaattgcgg tgtgcgtttg
    17101 tattgccgca cttacagtag cattttttgc aggcggcaac cgatcggaaa ataaagttca
    17161 aactgcatca actgcctcct cgctatcgac aacaaatgca gacacagaaa caacttctgt
    17221 gtctgcaaca gagaaaacca ctcaaaatcc taccgattcc actaaatcga acaaagataa
    17281 aaaggacaga aataattccg aagataaaaa gaacagtaag gataattcgc agaacagtaa
    17341 cggttcagct gttgaaaaaa gtgagaaatc cgagcagagt tcaaacaaca gttcttcgga
    17401 taagaaaaaa ccgtcttctt catcaaacag ttcttcaaag ccgaacaaaa agaatgatgt
    17461 tcaaccgaca acgcaggaca agtacaaaac cgatcctgta ccgtcgggaa aaccaaagcc
    17521 ggttgaaccg gaagaacagg aaacgaaaga tacaaatctt tattgtacct ttacaatcac
    17581 ctgttcaaca attcttgaca atatagatga ccttgatccc gaaaaaattg aactcgttcc
    17641 aaaggatggt ataatcctca aaaaacagaa ggtccaattc aaagagggcg aatctgtata
    17701 tgatgtcctt gtaaaagttt gtaaggacaa caatattcat atggaatcga gctggactcc
    17761 tatgtataat tccgcttata ttgaaggaat taacaacctc tacgaatttg actgcggttc
    17821 tctttcgggt tggatgtaca aagtcaatga atggtttcca aactacggct gttcacgata
    17881 tgtgctgaaa aacggcgacg atgtggtctg gtgctacact tgtaacttag gctatgatgt
    17941 cggcggagga tacgcaacag gagaataatg atgaaggata ctttttcaaa tatgcacccc
    18001 tttatcaatt ttatattttt tgcacttaca atagggttca cgatgtttat catgaaccct
    18061 gtttgtcttg ctgtcagttt tttatgtgcg cttgtaaccg ctttatacct taacggcaaa
    18121 aaagctgtga gattgtcact tgtttttctt ttacctatga tactcttgat agttctcata
    18181 aatcctgttt ttaatcatga aggaatgact atactcacat attttccgtg ggataaccca
    18241 ctaaccctcg aatcaatcgt ttacggtatt gcaagtgcat ttttgctttc gtcaacagtt
    18301 ttatggtttt cttcattcaa tgcagtaatc acttccgaca aggtagtttt cctgtttggc
    18361 agaataatgc cgtcattgag tctggtgatt tcaatggcat tgcgttttgt tccaaggttt
    18421 tcggcacaaa tgaaacttgt gcgtagtgca caacacacaa tcgggagaga tataaacgag
    18481 ggaacattgt ttcaaagaat aagaaatgca gtaaaaattc tttcgattat gataacatgg
    18541 tcacttgaaa acgcaattga aacagccgat tcaatgaaaa gcagaggtca cggtcttaaa
    18601 ggcagaacat cctattcact ttataaattt gacaaaagag acgcatttat gctttgcaca
    18661 atccttttta ccggattggt acttatgatt ttgcttttta caaaagcaat aaaattcaga
    18721 tactatccgt caatcaaggg cgatttgttt acggtgcaaa gtgttgtttt ttatatattc
    18781 tacacatttt taatgttgat tccgctatcg gtaaatatag gagaggggat aaaatggaaa
    18841 catatgcaat caaaaatctg agttttcgat accccgaaac cggtattgat gtacttaaag
    18901 atattacttt cagcgtaaat gagggcgagt ttatcacagt ctgcggtccg tcaggctgcg
    18961 gaaaaagcac acttctcaga catctgaaac ccgatctttc accgcacggt gttctttcgg
    19021 gagaaatatt ctttgaagaa aaacctatat cagacctttc tcacagggag caaagcagta
    19081 aaatcggctt tgttatgcaa tcacctgaaa atcagattgt taccgataag gtatggcacg
    19141 aacttgcttt cggacttgaa agtcttggtt atgacaacaa tacaatccga aaaagagttg
    19201 ccgaaacagc ttcatttttc ggaatccaaa attattttga aaaaagtgtt ctcgaacttt
    19261 cgggcggaca aaagcaaatt ttaaaccttg cttcaattat ggcaatgcaa ccgtccgttc
    19321 tcattttgga tgaaccgaca agccaactcg atccgattgc ggcaagcgaa tttttgcact
    19381 gcgtttcacg cataaatcac gaactgggga caacggtgat aataacggaa cacagacttg
    19441 atgaggtgct tccgctttca gacagggtgc ttgtcatcga aaacaacgga atttcagctt
    19501 ttgactctcc tcaaaaggtc ggaaaaattc ttaaagaaaa agacagtaaa acatttcttt
    19561 ctatgcctgc tccgatgcaa atatggcagg ctgttacaga aaatgacaat accgactgtc
    19621 ccgtaactgt tccaagcggc aaaaagtggc tttcggaata tgcccaaaat cataaaatgt
    19681 atgagctcaa acccgaaaat attctgaaac actctgataa agaagcagta agtcttaatg
    19741 atatttggtt caggtacgaa aagtcgggta cagatgtact aaaaggtctt tcactaaaaa
    19801 tatatcaggg ggaatttgcg gctatactcg gcggtaacgg aatgggaaaa tcaaccgctt
    19861 tgtcaattat ctgttcactt aacaagccat acagaggcaa agttgaaatc tctccgctta
    19921 acaaaaattc ttttgacacg ctcgtagcag tattacccca aaatccgcag acactgtttt
    19981 tgaaaaaaac tgtacttgaa gatttatacg aagtatttga cggcagaaaa atcagcaagg
    20041 aggaaaaaga aagacgggtt accgcagcgg taaagctgtg cagacttgaa agtctctgca
    20101 atcgccatcc ttatgattta tccggcggtg aacagcagag agcggctctt gcaaaaattc
    20161 ttctcataag acctcaaatt cttttgcttg atgaacctac aaagggactt gatgccgaat
    20221 tcaagattga gtttgctcag attatatatg acctcaataa agccggcata accgttctca
    20281 tggtaagtca cgatgtagag ttctgtgctg tatatccaag ccgctgtctg atgtttttta
    20341 acggtgaagt tgtgtcggaa ggtacaccga gaactttctt ttcgtcaaac agcttttatt
    20401 ccacctctgc aagccgaatg tcaaaaggca taatagataa cgcagtatca tcaaatgatg
    20461 tcatatatgc ctgcacaggt aaaaacagaa atattcaaat tgacaggaac acgcctgata
    20521 ttgacctttt taaaaatgac accgaaaata ttcccctcca aaaaaacaaa gctgaaaaca
    20581 aaaagctttc tgtttttaaa aaaatcttcg gattttttgg cgcagtactg ttcatactcg
    20641 gtctgattat aaacctggaa tatattccga atttttcagc caaaactttg cctacctggt
    20701 tcaactgggg aattatcgga gtatctgttg cgttgcttat gattgctttc ggaacaaaat
    20761 caaaacgacc gattgacctg ccgagaaaaa gttcaaaact gagtaaaaga accgtcagta
    20821 tggcaattat ggttttgctt gcaattcctg ttacaatttt tgttggaatg acatatcttc
    20881 aggatcagaa atatcttttt atttcactcc ttgttatgat tgagtgtatg attccgtttt
    20941 ttcttgtttt tgaaggcagg cacccaaaag cgagagagct tgtcataatt tccgttctat
    21001 gtgcaatagc agttgcagga cgacttgcat ttacaatgtt gcctcagttc aagcccgttg
    21061 tggcaattgt gataatttcg ggagtagcat tcggcggtga atcgggattt cttgtcggtg
    21121 ctgtaagtat gcttgtttca aatcttatgt tcggtcaagg tccttggacg ccgtggcaaa
    21181 tgtttgcggc aggaataata ggcttcattg gcggcattct ctttaagaaa ggtcttttgg
    21241 gcagaacaag gacttcgctc tgtatatacg gtttcattgc cacaatggtc atttacggcg
    21301 gacttatgaa cctttattcg gcactcacat cacattccgc atttaatcta aatatgctca
    21361 taacttttta tgttcagggc tttccgatgg atattgttca cgcagtttcg actgttatat
    21421 ttctgttttt cggagcagaa cctatgcttg aaaagcttaa cagaattaaa gttaagtacg
    21481 gacttatcga ataaacctaa acagcagata aaatttctgc tgtttttttg tgctgtaatt
    21541 caaaaatttt cgacaaaagt atagacataa tccgaaaata atattataat tttggtgtgt
    21601 ctgatttt
//
