LOCUS       gnlProkkaCFHMEBGC_13   15828 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CFHMEBGC_13.
ACCESSION   gnlProkkaCFHMEBGC_13
VERSION     gnlProkkaCFHMEBGC_13
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:14:03
            Original ID  :: gnl|Prokka|CFHMEBGC_13
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15828
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15828
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1:8311]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..8311
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..15828
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15828
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(2..469)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_1"
                     /sec_met_domain="AgrB (E-value: 2.4e-35, bitscore: 112.1,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKLLKNVLSCMRTKGLLDENEEDVYRFGLECLLLEVVHYLSYIV
                     IGFAMRMIMPMIVTAMVLIPLRRKSGGFHARTRSGCYLFSCSIVVAVCLLDKIIFPLWL
                     CTITTFGANAIIFAFAPIENENRTLDQEEQKKFRKQALIILVLADMAIIISH"
     CDS             complement(479..625)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_2"
                     /sec_met_domain="TIGR04223 (E-value: 5.3e-16, bitscore:
                     49.0, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLNDVALKLLAKAAYANAEKEANSACLFIGYQPKMPQKVKELK
                     ERK"
     CDS             complement(1041..2099)
                     /locus_tag="ctg13_3"
                     /transl_table=11
                     /translation="MFKKMPVCRLMISCPSDVKTEIEIINRVVDNINDSIGFSMNIFVK
                     TLYWSKNVMPEAGEYPQSIINKQILDKSDAIIAIFGNRIGSPTQHYESGTIEEIELMIQ
                     KGKQVFVYFSDKPVRKSEIDMEAETKIQAFKEKYKDRGIYVVYASDEEFNDYVSMHLTR
                     YLTTELANEVNRVNEHTRFDDSISQRKEVDLIYDYTKFYDIKQVSSYTDSNIMKIRTHK
                     DSFEMDIDIINVNKIENKEFAMALFEYAPCDNWSAFFEAGYFFEFDAASSGDIRAFQLE
                     IKDDIRNKVIDRTLQVSCEEEHFRIWIPSTTRDSTAWKKISQVCFVVFFNSTYIDGEKG
                     LLTIRNLKMVPR"
     CDS             complement(2306..2428)
                     /locus_tag="ctg13_4"
                     /transl_table=11
                     /translation="MFDIVTGRLGVVLISLLFYVLLRNCNKKIRSKCKIVVLLS"
     CDS             complement(2506..3012)
                     /locus_tag="ctg13_5"
                     /transl_table=11
                     /translation="MFNLSKKKINKIMAFAIAFTMLFASQVTAFAATTSSKTVTSSKAM
                     SVALLPGVTGNSNTITFNFNSLPDKAIVKEVEIDCSNASVIGGKGAILAKSLTITSPSG
                     ETHTVSWGKGNVTTTNLFIAEKAAGTWSVYMTGTNIASPNLGSAFIGGTKYSSVKMKVS
                     YILED"
     CDS             complement(3057..3647)
                     /locus_tag="ctg13_6"
                     /transl_table=11
                     /translation="MEISNNYSTAKVWNTSNKNVSKSSEKNKWKLTDSLKEKIVVIWQK
                     KDAQDNVYMGNAFMNLRKTEVSKVAPNRAALIGKFSQSMNSGNMSAVKEVEEADKKWLC
                     MLFGIPYEAKYQGTGTGSAIHVYNEEGEEVLTYTGGVGWQEKETKAESQVHSALKMTYY
                     EAFSEARKALNSEEKTGSVGENIILQDNFDMKA"
     CDS             complement(3677..4246)
                     /locus_tag="ctg13_7"
                     /transl_table=11
                     /translation="MSIAGINGYNYSNYYTGTKRNTAKANGMNSGLLSNVSSTSSNITL
                     HMSGTEDSGNALTAVGFPDGSSASVYKSDAYDSANPEYRVRYWDKEGNYTDTNVQINDV
                     DPRNASYLEMLAYTTYSDVEGFTKNAFGDFMNAAGGVNGNITYDSDSINEKKDYMSMIK
                     EFMQLQYDSNNLSGQVICHIRNCMIT"
     CDS             complement(4366..4836)
                     /locus_tag="ctg13_8"
                     /transl_table=11
                     /translation="MKKIFKIISLVMMMVMCFSVTAFAAETDETSNLKVSFTDEGMINT
                     VDEDVTPGISVRAPAPAVSSVKVVAAQIKSDGYVYVTVQVAGYGKNIYATYDGSQCYVS
                     STTSIGKPIVTGYLYEVKCAKAVVGSHNFTFRITSVNSPWNTMSTSSIITVK"
     CDS             complement(5141..6433)
                     /locus_tag="ctg13_9"
                     /transl_table=11
                     /translation="MNTILLVLCNALSCFIISTILFQFMNGKYKKSSRNRYVYIVIETT
                     TVIFTFCINMLNHSILNLVVWGVLTGIIAYVLYYEDIDKPLRRIIECEALVFCMSVCES
                     LGVILLQCILQAADIKNVNETMLYCLEVTFSKVILIFLYYTFINRFVKKSDVPYSNTRY
                     IMYGIILLYSLINMSVIVENFKNGEENYLCAVNMGCIVLADLYLLYFVKMADEKNYYEK
                     QLIALEQQAKVQYEYYLTQAKKYDQTIQILHDVNKHIKAIEGLYGAEQEKTAGEYATKI
                     RELLKPLIPVQYTENPILNILLTDKESVMREKGISVTIKVDNVNLNFIEPIDITTIFGN
                     LLDNAIEATEKLKGEKYICIKIGSYHKMIVVSIENNCNEVKWKNGFPVSNKGKNGGIGL
                     LNVQSSIKKYDGDLTLKNDGNKFAAELFLNS"
     CDS             complement(6442..7176)
                     /locus_tag="ctg13_10"
                     /transl_table=11
                     /translation="MLEIAVCDDDIADLECAVNMLHKIFTSQKIAYHIEKFMSANQMLE
                     NISRIDIGILDISMEELNGIKLGRKLKEKFPDVKLVYITSYEEYCMQVINEVHAFSFLC
                     KPLEYDKLELQILELLNQLPDAIVEKNFYKVTDSNGKEYLSIKLKLRDILYFEYIKRSR
                     KVLIALSDITYEYDCIFEKLVEELQPYDFVVNCRGNLVNLRHIEKIKGFIIYMDNGKEL
                     QIAQRRSNDFREEVNKFLQRNS"
     CDS             complement(7548..8132)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_11"
                     /sec_met_domain="AgrB (E-value: 2.3e-41, bitscore: 131.7,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAKFAKKINEILIQKEIVQKEDAELYQYGIENGIVVAGNLLASG
                     IFGIVTGRPGLVLVFLLFYASLRSYSGGSHCKSRIGCFLISMAILFIPVYTYEPVMKNV
                     PNAVILLIGVLAVVIIIVLAPVESINKPLDEEERRYYARVTHCITALQVCVLIILFCLD
                     LQDYFYAGYVSIVLVAVFMVMGKIAVKRYVQ"
     CDS             complement(8147..8311)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_12"
                     /sec_met_domain="TIGR04223 (E-value: 2.3e-12, bitscore:
                     37.4, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLRRLMNRLSHGALTSVAALALTVTATNMNRCCWFIFGQDKLP
                     DNAKKLRKF"
     CDS             complement(8415..9701)
                     /locus_tag="ctg13_13"
                     /transl_table=11
                     /translation="MEYVIRFAISLFDLAVFMYYFHSNKKMKPVSKVWILAGFTIAAII
                     WTFVSSIKNPYLNLATLLIVLILLSFYYISGMWTRIINIVTFMGIGMLFEPVALLLLHA
                     MNFHMGESYKYYFVMVICSFVRGNVMYILSKLISKKGMQIADFPREILGVLVMVFTFTV
                     LNCCFVILLSLEAGSEKSLLMCASIVISIVLTDYFMLYMMERFNYLVQKQYEDAMYREE
                     MHYKDIYYEEAEKQNKEVQKLKHDMKHKLHELYHLLENSDGHELSEKIGAMCIEFEQID
                     EKQYSDNPIVDSVLRIKFGRAKARGIKVETSIRIPKKMQLDHGDIGVLYGNLVDNAVED
                     CSKVPEGQRFVKIENKYQSGILLLVITNSKTGKKNKSLKTTKKDNIRHGHGVQSVRKVV
                     EKYNGTVSFTDKGDIFEVSAMLYGIEVKE"
     CDS             complement(9704..10411)
                     /locus_tag="ctg13_14"
                     /transl_table=11
                     /translation="MLNIAVCDDSRTDVEMLESAFDKLAQYQFSYEVYFTAKELLKHVI
                     DDGEMYHLYIFDIEMPEMNGLQLAKEIRKIDAKALFVFLTGYTQYVMDVFEVITFDYIS
                     KPITVEKLESVLLKAMQYLHMIKRDFVFQFRKNQFRISCDDIVYFEKKGRQAVIHTISE
                     NFKANMTTEEIWKQLDDKVFAHIHVSYIINLGHIRAIEGDEVVMDNEERLLIARSHKQN
                     LKEKHMEFVRRMV"
     CDS             complement(10456..10788)
                     /locus_tag="ctg13_15"
                     /transl_table=11
                     /translation="MDTGRKDANIQIGKRLREARLNMNLEKSEIADVLDVTVEHYRKLE
                     AGITGISVDKVLTLYHKYGIDPTYLITGESSMKDFNLDYYVANSTKEQRNDFFDRVLAY
                     LSKLIR"
     CDS             complement(11534..12448)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 268.1; E-value: 1.2e-81)"
                     /gene_kind="other"
                     /locus_tag="ctg13_16"
                     /transl_table=11
                     /translation="MTEAIYLEVTEKTEAAQKAGRRFSVSGMLKFLGVSRSGYLAWLHH
                     VPSDTEKRRKAVKAKIQDIYDDSKQNYGAPKITVELRKTGEVISERTVGTYMRQMGIRA
                     QWSKPWTITTKDSDFSTELQNILDEQFNPDRPNAVWCSDITYIWTIDGFVYLTSVMDLF
                     SRKIIAWTLSETLEVSCVIDTINKAKARRNIDQPLIIHSDRGSQYVAKEYKKATENMQR
                     SYSKKAFPWDNACIESFHSIIKREWINRFKIRDYKQAYQLIFEYLEAFYNTKRIHSHCN
                     YMSPNEFERLYERTHTEAELLAG"
     CDS             complement(12445..12648)
                     /locus_tag="ctg13_17"
                     /transl_table=11
                     /translation="MCRKSWHRLQYINKVAERLPESGDIPVRGSGNYASDEQKEIARLR
                     RELRDAKDALDVLKKAINILGK"
     CDS             12669..12995
                     /locus_tag="ctg13_18"
                     /transl_table=11
                     /translation="MILIVLDCIKFKLFVMLLCHMRSSFSMFLLYHAYVYLEFLILACT
                     IYILAPEARKEVIRLLGGVISGMNVGQPVIMQAANSEAQEPTEDVMDDADVAGLAMGWM
                     SKGD"
     CDS             12952..13272
                     /locus_tag="ctg13_19"
                     /transl_table=11
                     /translation="MLQDLQWDGCRKETDYYEKSYGSRRNSNFRDTQVDIKDNSWSVEA
                     GLRTCQNNSSSIRYGGKDISFIRKNGHILRGGERMQVKGLFLNYKKNRRLMQYFFKIRE
                     LV"
     CDS             13637..14485
                     /locus_tag="ctg13_20"
                     /transl_table=11
                     /translation="MMNYEIFKEVVKEKFMDYMPEKFKGMELVVEPVEKVNVTLDGIIL
                     REEGRNISPTIYINDMYKKYQDCGDLEETLMAACDFMERAYEQAPVVDVDSIMRDANEK
                     IVFQLINTEQNKTFLEQVPHREFQDLSIVYKVIISADKDAVQSSKITNEFAKRLGMSEE
                     QLFKCAAENTRRLFPPVVRSMNDIMREMFARDGMPQEIADMMIAEIPPEQTMWVISNEK
                     GINGAASMLYENELHELAESLESDLYILPSSVHEVIAVSSDMGSPEMLAQMVVEVVLEY
                     K"
     CDS             14564..14839
                     /locus_tag="ctg13_21"
                     /transl_table=11
                     /translation="MKNNIDDINGWLYHRIRMCIWKQWKKPRTKARNLIKMGVPEDLAM
                     QAGNTRRGHWFATHTVAINMAMTKEKLINSGFYDLATAYQSVHVNY"
     CDS             14976..15536
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 122; E-value:
                     5.4e-37)"
                     /gene_kind="transport"
                     /locus_tag="ctg13_22"
                     /transl_table=11
                     /translation="MLHGIDLTLPAGSFTALVGPSGGGKSTTARLISRFWDVTEGNITI
                     GGVNIKDMSLEQLSEMVSFVTQDNFLFRCSLLENIRLGNPAASDEEVREAAGKACCEEF
                     IEKLPMGYDTPAGEAGKRLSGGEKQRIAIAHRLTTIEQADQILVVDDGQIVQKGTHREL
                     ASVPGKYQDFVEIRSQSEGWKIG"
ORIGIN
        1 tgtgtgatat aataattgcc atatctgcca atactaaaat tattaacgcc tgttttctaa
       61 attttttctg ttcctcttga tctaatgttc gattttcatt ttctattgga gcaaatgcaa
      121 atataattgc atttgcccca aatgtagtta tagtacataa ccatagtgga aaaatgattt
      181 tatccaataa acataccgca acaactatgg aacatgaaaa taaatagcat ccactccttg
      241 ttctcgcatg aaagccaccc gattttctac gcaatggtat taacaccatt gcagttacaa
      301 tcatgggcat tatcattcgc atagcaaaac caattactat gtatgacaag taatgtacca
      361 cctctaacaa taagcattct aagccaaagc gatatacatc ttcctcattt tcatccagaa
      421 gtccttttgt cctcatgcaa gatagaacat ttttcagcaa tttgtccata ggaaaatatt
      481 attttctttc tttcagttct tttactttct gtggcatttt aggctgatag ccaataaaca
      541 ggcacgctga atttgcctct ttctctgcgt ttgcatatgc tgcttttgca agtaatttca
      601 atgctacatc attaagtttt ttcatgcttg aaaacctcct tattttttct ttttctatcg
      661 acaagcatct tataaaattt tacctttttt gcaccaagta cgattttttt gcacgaagta
      721 agacttttca cttattaaaa agccaaaatg ctgatgaata taatatcatc tgttttgtta
      781 cttcatatat ttttattgat aaacatattg atattacgag cgatcgcatt catattgtca
      841 aaaaaatagc acctaaacca caaatggatt agatgcatat aattttttct attattttat
      901 ttgcttatct acaattttaa ttttctgtta ctgctttaaa tccgaaaatt gcttacctac
      961 ctaaataagt ctatcattac ctcttacatg attttcctcg atatctttca gacttttctg
     1021 catactttca aagtattatc ctatcggggc accattttaa gatttctgat tgtcaacaga
     1081 cctttttctc catcaatata tgtactattg aaaaatacaa caaaacaaac ctgcgatatt
     1141 tttttccacg cagttgaatc tcttgttgta gaaggaatcc atattcggaa atgttcttcc
     1201 tcgcagctaa cctgtaatgt tctatcaatt accttatttc gtatatcatc ttttatttcc
     1261 aattgaaaag ctcttatatc gccactactt gccgcatcaa attcaaaaaa atatcctgct
     1321 tcaaaaaaag ctgaccagtt atcacatgga gcatattcaa ataatgccat tgcaaattcc
     1381 ttattttcta ttttatttac attgattatg tcaatatcca tttcaaaact atctttatgt
     1441 gttcttattt tcataatatt tgaatcagta taagaactaa cctgttttat atcataaaac
     1501 ttagtataat cgtaaattaa atcaacttct tttctctgtg atatagaatc gtcaaatctt
     1561 gtatgctcat tcacacgatt tacttcattt gcaagttccg ttgtaagata gcgtgtaagg
     1621 tgcatactga cataatcatt aaattcctca tcagaagcat aaacaacata tattcctctg
     1681 tccttgtatt tctccttaaa tgcctgtatc tttgtctccg cttccatatc aatttcactt
     1741 tttcgtactg gcttatcaga aaaatataca aatacctgtt ttcccttctg tatcatcaat
     1801 tcaatttctt ctattgtccc tgattcataa tgttgtgtag gacttcctat tctattacca
     1861 aatatagcaa taattgcatc cgatttatct aaaatctgtt tattaataat gctttgtgga
     1921 tactctcctg cttctggcat aacattcttt gaccaataca atgtcttaac aaaaatattc
     1981 atagaaaaac caatggaatc atttatatta tccacaactc tgttgataat ctctatctct
     2041 gttttcacat cggaaggaca ggaaatcatt aatctacata ccggcatctt cttaaacata
     2101 acttttcccc ctttgcgttt tatttagtac agcagactac tataattatt accataatac
     2161 aacactgcct acttttttaa attctgagat ttcattcaac aacaaccaat tttttattat
     2221 attataccag ttttttctac ttttttaaat atattcatta caaactcaca actcatatac
     2281 aaaacagaat aaacaaaaat tccatttaac ttaataaaac aacaattttg cacttactac
     2341 gaattttttt attacaattt ctcagcaaga cataaaataa cagggaaatc agaacaactc
     2401 ctaatctccc tgtcacaatg tcaaacatat tctggaatcc aatattttta cattatttgg
     2461 tattctccat aagcaactta taaatatcca atgtacttta taattttaat cttctaaaat
     2521 ataagatact ttcattttta cagatgaata ttttgtacct ccaataaatg ccgagccaag
     2581 atttggcgac gcaatattag ttcccgtcat atacacagac catgtacctg ctgctttttc
     2641 tgcaatgaac aagttggttg tcgttacatt tccttttccc caactaactg tatgtgtttc
     2701 accactagga cttgtaattg taaggctctt tgccaatatt gctccttttc ctccaataac
     2761 agatgcattt gaacagtcaa tttcaacttc ttttactatc gctttatctg gtaagctgtt
     2821 aaaattaaat gtgatggtat tagaatttcc agtaactcct ggtaacaatg caacagacat
     2881 tgcctttgat gatgtaacag tttttgatga tgtagttgct gcaaaagctg ttacctgaga
     2941 tgcaaacagc atcgtaaatg ctatagcaaa tgccattatt ttatttattt tctttttgct
     3001 taaattaaac atagatattt tcctccaaat tatagacctt attttaattg catacttcat
     3061 gccttcatat caaaattatc ttgcaatatt atgttttcac ctacactacc agtcttttct
     3121 tcactattta atgcttttct cgcctcacta aatgcctcat aatatgtcat ttttaatgct
     3181 gaatgaacct gtgactctgc ttttgtttct ttttcctgcc agcctactcc ccctgtatag
     3241 gtcaaaactt cttcgccctc ttcattgtat acatgaattg ccgagcctgt ccctgttccc
     3301 tgatattttg cctcataagg tattccaaac agcatacaga gccatttttt gtctgcttcc
     3361 tcaacttctt tcactgctga catattacct gaattcattg attgactaaa ctttccaatt
     3421 aaagcagctc tattcggggc tactttgctt acttccgtct ttctcaaatt cataaatgca
     3481 tttcccatat atacattgtc ctgtgcatct tttttttgcc agatcacaac aatcttctct
     3541 tttaaagaat ccgttaattt ccatttgttt ttttcagaag atttagaaac atttttattc
     3601 gatgtgttcc acacttttgc tgtgctataa ttatttgata tttccattta attgaatcac
     3661 ctctctgttc tgtcatttat gtaatcatac aattccttat atgacagata acctgacctg
     3721 ataagttgtt cgaatcatat tgtaactgca taaattcttt aatcatgctc atatagtctt
     3781 tcttttcatt tatgctgtca gaatcataag tgatgttgcc attcacacca ccagccgcat
     3841 tcatgaaatc tccaaaagca tttttcgtaa agccttctac atcactatat gttgtatatg
     3901 caagcatttc caaataactt gcatttcttg gatcaacatc atttatctgt acatttgtat
     3961 ctgtgtaatt tccttctttg tcccaatatc ttaccctgta ttctgggttt gccgaatcat
     4021 atgcatctga tttatataca gatgcactac tgccatccgg aaatcctact gctgttaatg
     4081 catttccact atcttctgtt cccgacatat gtaatgtaat attagaagat gtactgctta
     4141 catttgataa caaaccggaa ttcataccgt tcgctttcgc agtgtttctt tttgttcctg
     4201 tataataatt tgaataatta taaccgttaa ttcctgctat actcattttc gtttcctcca
     4261 attattttca ttcctctgtc attcggaatc tactcactct ccataacggt ccaagtgatt
     4321 tattgctttt tataaaagga cacctattat acacactttc gttttttatt ttactgttat
     4381 tattgaactt gtagacattg tattccacgg tgagtttaca gatgtaattc taaatgtaaa
     4441 attatgtgaa ccaacaactg ccttagcaca ttttacttca tatagatatc ctgtcacaat
     4501 cggctttcca atagaagttg ttgaagatac atagcattgc gatccatcat atgtcgcata
     4561 aatatttttc ccatatccag ctacctgcac tgtaacatac acatatccat cactttttat
     4621 ttgcgctgca actaccttta cgctcgacac tgctggtgca ggagctcgaa ctgaaattcc
     4681 aggtgtcaca tcttcatcaa ctgtatttat cattccttca tccgtaaaag aaacctttaa
     4741 attacttgtt tcatctgttt ctgcggcaaa tgccgttact gaaaagcaca ttaccatcat
     4801 cataactaat gatattattt taaatatttt cttcatgtat ttttcctcca tttttatagg
     4861 tgtccttttt tatccattac aattttctgc tattttatct tccctttgca gcaacattcg
     4921 gatcattgtt cgcctcaaag gaatattgtc aagtgtgtaa accgtagtcc gtaattcttg
     4981 acataagcga aacctcccat cattaaattt tttatatgta tcatccactt tatttttttc
     5041 tatcgacaca ccccttctga tattttacct tttctgcacc aagtacgatt tttttgcacg
     5101 aagtaagact ttttacaaaa aaatagccaa aaatgctctt ttatgaatta aggaataact
     5161 cagcagcaaa tttatttcca tcattcttca atgttaaatc tccatcatat ttttttatac
     5221 tgctctgaac attcagcagt cctattccac cattttttcc tttatttgat actggaaaac
     5281 catttttcca ctttacttca ttacaattat tttcaatgct gacaactatc atcttatgat
     5341 atgagccaat cttaatgcaa atatatttct cgcctttcag cttttctgtt gcttcaatcg
     5401 cattatctaa taaatttcca aaaatagttg taatgtcgat tggttcaatg aaattcaaat
     5461 tcacattatc tacctttatt gttactgaaa tccccttttc tctcataaca gattctttat
     5521 ctgtaagaag tatattcaag atcggatttt ctgtgtattg aaccggaata agcggcttca
     5581 acaactctct gatctttgtt gcatattctc ctgccgtttt ttcctgctct gcaccatata
     5641 acccttcgat tgctttaata tgcttattta catcatgtaa tatctgaatg gtttgatcat
     5701 acttttttgc ctgggtcaaa tagtattcgt attgtacctt tgcctgctgc tctaatgcga
     5761 tcaactgctt ttcgtaatag ttcttttcat ctgccatttt tacaaaatat aaaaggtata
     5821 aatctgccag aacaatacat cccatgttga ctgcacacaa ataattttct tctccatttt
     5881 taaaattctc tacaattaca ctcatgttaa tcagactgta tagaagtata attccataca
     5941 tgatgtaccg tgtatttgaa taagggacat cacttttttt cacaaacctg tttatgaatg
     6001 tgtaatacaa aaaaataagt atcacctttg aaaatgttac ctcaaggcaa taaagcatag
     6061 tttcattcac attttttata tctgcggctt gtaaaataca ttgtaaaaga ataactccta
     6121 atgattcaca gacagacata caaaatacta atgcttcaca ttcaataata cgtcttaagg
     6181 gtttatctat atcctcataa tacagaacat atgctataat ccccgtcaaa actccccaga
     6241 ctactagatt taatatggaa tgattgagca tatttataca gaatgtaaat attactgtgg
     6301 tagtctcaat cacaatatat acatatctat ttcgactact ctttttatac tttccattca
     6361 taaactgaaa taatatcgta cttattataa aacatgaaag tgcattacat aataccagta
     6421 aaatcgtatt catttttcct cctatgaatt tctctgcaaa aatttattta cttcttctct
     6481 aaaatcgttg cttctccttt gtgcaatctg aagttctttt ccattatcca tataaataat
     6541 aaagcccttt attttttcaa tatgccttaa attaaccaga tttcctctac aattcacaac
     6601 aaaatcatat ggttgcagtt cttcaaccag tttttcaaag atacaatcat actcatatgt
     6661 aatatcagac aatgctatca gtacttttct ggatcttttt atgtattcaa aatataaaat
     6721 atccctcagt ttcagtttga tcgacagata ctcttttcca ttgctgtcag tcactttata
     6781 aaaattcttt tctactatgg catccggcag ttgattcaga agttccaata tctgcaattc
     6841 cagtttatca tattccaatg gtttacatag aaatgaaaat gcatgaactt cgttaatgac
     6901 ctgcatacaa tattcttcat aactcgtaat atacactaat ttcacatctg gaaatttttc
     6961 tttcaatttt ctccccagtt taataccatt cagttcttcc atcgaaatat ctaaaattcc
     7021 gatatcaata cgactgatat tttcaagcat ttgatttgca gacataaatt tctctatatg
     7081 ataagcaatc ttttgacttg taaaaatctt atgcagcata ttcactgcac actcaagatc
     7141 tgctatatcg tcatcacaaa cagcaatttc cagcatatta ttcaccttct tcctatcttc
     7201 ctactatatc ggtaattttt atctttccat taaataaata taaagcactc cgcatattat
     7261 ctaaataaat atcatatata tagaaaatgt gccatcatct tgacggcaca tttttcattg
     7321 ttgattttgc tgtcaaaaaa tcaattatac agacgattac aaatactatt gataactttt
     7381 ttactacttc accataacca tatcattttt cctacttttt tcaatatatc ttgcacgaag
     7441 tacgattttt tcaacacaaa atacgacaaa acgtaaattt ctccccatct tagccaatct
     7501 tatgtaaaag cagtcacaaa tttaatatat cattttaaga ggattttcta ttgcacatat
     7561 cgtttcactg caatctttcc cataaccata aatactgcta ccaggactat acttacatac
     7621 ccagcataaa aataatcttg cagatccaga caaaacaaaa tgataagaac acatacctgc
     7681 aatgccgtta tgcaatgtgt tacccttgca taataccttc tttcttcctc atcaagcggt
     7741 ttattgatac tttccactgg ggcaaggaca ataataatta ccacggcaag aactccgatc
     7801 aataaaatca cggcattagg aacatttttc attacaggct catatgtata aaccggaata
     7861 aataaaattg ccattgatat caaaaaacag ccgattctac tcttacagtg gctgccccca
     7921 ctatagcttc tcaacgaggc ataaaataac aggaagacca gaacaagtcc cggtctcccc
     7981 gtcacaatgc caaatattcc agaagccaaa aggtttcctg caacaacaat gccattttct
     8041 atcccatatt ggtacagttc tgcatcctct ttttgcacaa tctccttttg tatcaatatt
     8101 tcatttatct tctttgcaaa tttagcaatc ataccctgtt accaccttaa aattttctaa
     8161 gttttttcgc attatccggt aacttgtcct gtccgaaaat aaaccagcag caacggttca
     8221 tattggttgc agttaccgta agggcaagtg ctgccacgct ggttaatgct ccatgactga
     8281 gtcggttcat caatcttctt aattttgaca tatatgtatg tcctcctttg catttgatga
     8341 atgcactata tcatacttta caggaaaatg cggcaaagtg taacagattg acatttaagt
     8401 gtaacgcttt gcatttattc cttcacttca attccataga gcattgctga aacctcaaat
     8461 atatcccctt tatctgtaaa acttaccgtt ccattgtatt tttctaccac tttgcggaca
     8521 ctctgaacac catgcccatg tcggatatta tctttcttgg ttgttttcag gcttttattt
     8581 ttctttcctg ttttgctgtt tgttattaca agaagcaaaa tccccgactg gtacttattt
     8641 tcaatcttta caaaacgctg tccctccggc accttgctac agtcttctac cgcattatcc
     8701 acaagatttc catacaatac acctatatcc ccatgatcaa gctgcatctt ctttggaata
     8761 cgaatagatg tttctacttt tatccccctt gcctttgccc tgccaaattt aatgcggagc
     8821 acagaatcta cgattggatt atcagaatac tgcttttcat ctatctgctc aaattctatg
     8881 cacatcgcac cgattttctc tgaaagttca tgcccatcac tattttccaa cagatgatac
     8941 agttcatgca atttatgttt catatcgtgc tttaacttct gcacttcctt attctgtttt
     9001 tctgcttctt cataatagat gtctttatag tgcatttctt ccctgtacat tgcatcctca
     9061 tactgttttt gcacaagata attaaaacgt tccatcatat acagcataaa ataatctgtc
     9121 aggacaatgg aaattacaat actggcacac ataagcaggc ttttttcact gccagcttcc
     9181 aatgacaaaa gaataacaaa gcaacaattc aacaccgtaa aggtaaatac cataaccagc
     9241 acacccaaaa tttctcttgg aaagtcggca atctgcatcc ctttctttga aatcaatttt
     9301 gacagaatat acatcacatt tccacgaaca aagctgcata ttaccattac aaaataatat
     9361 ttataacttt ctcccatatg aaaattcatc gcatggagta acagcaaagc tacaggttca
     9421 aacagcattc caatacccat gaatgtcaca atatttataa ttctcgtcca cattcctgat
     9481 atataataaa atgataacag tataagcaca atcaaaagag tcgcaagatt cagatacgga
     9541 ttttttatgc tactgacaaa tgtccatata attgcagcaa tggtaaatcc agccaatatc
     9601 catacctttg atactggttt cattttctta ttggaatgaa aataatacat aaacactgcc
     9661 agatcaaaca ggctgatggc aaagcgtatc acatattcca tccttaaacc atcctcctta
     9721 caaactccat atgtttttct tttaaattct gcttatggga acgggcaatc agaagtcttt
     9781 cttcattgtc catcactact tcatctccct caatcgccct gatatgccca agattgatga
     9841 tatatgatac atgaatatgg gcaaagacct tatcatcaag ctgtttccat atttcttcag
     9901 ttgtcatatt tgccttgaaa ttttctgaga tcgtatgtat cactgcctga cgacctttct
     9961 tctcaaaata cacaatatca tcgcagctaa tacgaaactg attttttcgg aactgaaaga
    10021 caaagtcacg ctttatcata tgaagatact gcatggcttt taaaaggacg gactccagct
    10081 tttccactgt aatcggttta gaaatatagt caaaggtaat aacctcaaaa acatccataa
    10141 catactgcgt atatccagtc aggaatacaa acaatgcttt ggcatctatt ttccggattt
    10201 cttttgcaag ctgcaaacca ttcatctccg gcatttcaat gtcaaatata tacagatgat
    10261 acatttcccc atcatctata acatgcttca gcaactcctt cgctgtaaaa tacacttcat
    10321 aagaaaactg gtactgcgct aacttatcaa aagcactttc cagcatttct acatctgttc
    10381 tgctgtcatc acagaccgca atattaagca taacacttcc tccttttcgg gcttggaagt
    10441 aggaagcact tcaatttatc taatcaactt agataaataa gccagcacac ggtcaaaaaa
    10501 atcatttctc tgctcctttg tgctgttcgc aacatagtaa tccagattaa aatctttcat
    10561 actgctctca cctgttatca gatatgtagg atcaattcca tatttatgat agagtgtcaa
    10621 cactttatct acagatattc ccgttatacc cgcctcaagc tttcgataat gttctactgt
    10681 aacatccaat acatccgcaa tttctgactt ttcgaggttc atattcagtc ttgcctctct
    10741 tagtctcttt cctatctgta tattggcatc ttttcttcct gtgtccaaga ttttgcacct
    10801 cttttccatg ttaatcatat caatgggact ttgattctca tagtccagaa aacaacccaa
    10861 tgcacatcat tttatgctcg tgagtaggtt aatttgtgct tttattaaaa aaacgaatgg
    10921 cacatctgat accattcgtc tttatctgct ttatattctg ttgtaaatcc tattagcgga
    10981 cgttttttgg ctatttatca tatccatcac tgcatttctt ttactctgac atccacagta
    11041 tttttaaaat tttcaatctg atgtgaatac tgttcattca taagagtgga atgaatcata
    11101 aaatccgctg ttgcaatatt atttgcaatt ggtatatttt ggatatttgt aaaatggcaa
    11161 aagccacata aattttactt ttttgcaagt aatttcatag ctatatcatt aagctttttc
    11221 atataaaaac ccttttattt ttcttttata tcgacaagca tcttataata tttcaccttt
    11281 tctgcacgaa gtaagatttt tttgcacgaa aagcataaag atgcattaaa gacattaaag
    11341 cataacgttt ttcttaatat aaaaaatctt agtttcctgc tcgataaaat caaaagaatt
    11401 atacttcgtg caataaatgc gtatttcgtg catagagagt gtaaatttat atttctgtat
    11461 gctattattt tccaaataat gttggtccta tgtcaagatt tagtacaagt taaaatgaga
    11521 aacttttccc attttaaccc gccagaagct cagcctcagt gtgtgttctt tcatacaatc
    11581 gttcgaattc atttggtgac atatagttac aatggctatg aattcgtttc gtattgtaga
    11641 aagcttccag atattcaaaa atcaactggt atgcctgctt atagtcgcga attttaaagc
    11701 gattgatcca ttcacgtttg ataatagaat gaaaggattc aatgcatgca ttatcccacg
    11761 gaaaagcttt cttcgaataa ctgcgctgca tattttcggt tgctttttta tattcctttg
    11821 caacatattg gctgccacga tccgaatgga taattaatgg ttgatcgata tttcggcgag
    11881 ctttggcttt gtttatcgta tcaatcacgc aggatacttc cagtgtttct gaaagcgtcc
    11941 aggctatgat ttttctggaa aataaatcca taacactggt cagatagaca aatccatcta
    12001 ttgtccagat gtaggtaata tccgaacacc agactgcatt cggacgatca ggattaaact
    12061 gctcatcgag gatattttgt aattcagtgc tgaaatcgga atcttttgtg gtgatcgtcc
    12121 atggtttgct ccactgagca cggattccca tttggcgcat atatgtacca acggttcttt
    12181 ccgaaatgac ttcaccagtt tttcgaagtt ctacagtgat tttcggagca ccgtagttct
    12241 gcttggaatc atcataaata tcctgtattt ttgcttttac agctttacga cgtttttctg
    12301 tatcagaagg tacgtggtgg agccatgcaa gatatcctga gcgagagaca cctaaaaatt
    12361 tcaacattcc ggagacggaa aaccggcgtc cagccttttg ggcagcttcc gtcttctcag
    12421 tcacctcgag ataaatggct tccgtcattt tcccagaatg ttgattgctt tttttaacac
    12481 atcaagtgca tcttttgcat cacgtaattc acgtctgaga cgggcaattt ccttctgctc
    12541 atcagatgca taattaccag aaccacgaac aggaatatca cctgattccg gaagtctttc
    12601 agccactttg ttaatgtact gtagccgatg ccaagatttt ctgcacatcc acgtactccg
    12661 agatctttat gatcttgata gtactggatt gcatcaagtt taaattgttt gtcatgttgc
    12721 tttgccatat gagatcctcc ttcagcatgt ttctattgta ccatgcttat gtgtatttgg
    12781 aatttctcat tttggcttgt actatttata ttctagcacc agaggctagg aaagaggtca
    12841 taaggctgtt aggcggagtg atatccggga tgaatgttgg tcagccggta ataatgcagg
    12901 cagccaatag tgaagcacaa gaacctacag aagatgttat ggacgatgca gatgttgcag
    12961 gacttgcaat gggatggatg tcgaaaggag actgattatt atgagaagag ttatgggagc
    13021 cgtaggaaca gtaattttag agatactcaa gtggatatta aggataattc ttggagcgtt
    13081 gaagctggtc ttaggacttg ccagaataat tcttcttcta ttcgctatgg tggcaaggat
    13141 atttctttca ttcgtaagaa tgggcacatt ctgagaggag gtgagcgtat gcaggtaaag
    13201 ggtttattct taaattataa gaaaaacaga agacttatgc agtatttctt taaaataaga
    13261 gagctggtat aatgaaagga gtttaagatg cacagaatac gggacagtcc tatgtgtccc
    13321 gtgcattaca gataaatagt tcactgcaag ggtggatggc acgatgtaac acttcgatat
    13381 gatgataatg caccggatgt tgttgtagca actcttaagc ttgtcaatgt accgacagag
    13441 cctaagcttc cacagacagg agacaatgca aatccgcttc tttatcttgg aattggtgca
    13501 cttgcactta ttacaggtgt tggagtcgga cttcgtggaa gaaagaaaaa gaataaacag
    13561 taacaattaa ccttgcgggg aatgtaagcc agtaacttat gttccccgct tttttagatt
    13621 aaggaggaac cgtaatatga tgaattacga gatttttaag gaagtagtaa aagaaaagtt
    13681 tatggattat atgcctgaga agttcaaagg aatggagctt gtggtagaac ccgtggaaaa
    13741 ggtgaatgtg actcttgatg gcatcatctt aagagaggaa ggcaggaaca tttcgcctac
    13801 gatttatatc aatgacatgt ataagaagta tcaggattgt ggtgaccttg aggaaacact
    13861 tatggctgca tgtgacttca tggaaagggc atatgagcag gctccggttg ttgatgtgga
    13921 cagcattatg agagatgcta acgagaagat tgtattccag ctcatcaata cagagcagaa
    13981 taagacattt ttggaacagg tgccgcacag agagttccag gatctttcta ttgtgtataa
    14041 ggtaataatc agtgcagata aggatgcggt gcagagttca aaaattacaa atgaatttgc
    14101 aaaaagactt ggaatgagtg aggaacagct ctttaagtgt gcagcggaaa acacaagaag
    14161 actcttccca cctgtagtac gaagcatgaa tgacattatg agagaaatgt tcgcaaggga
    14221 tgggatgcca caggagattg cagatatgat gatagccgag attccaccgg agcagacgat
    14281 gtgggtgatt tccaatgaaa agggtatcaa tggtgcagca tccatgcttt atgagaatga
    14341 gcttcatgag ctggcagaga gtttagagag tgacctttat attctccctt cgagtgtgca
    14401 tgaggttatt gcagtatctt cagatatggg aagccctgag atgcttgcac agatggtagt
    14461 cgaggtggtg ctagaatata aatagtacaa gccaaaatga gaaattccaa atacacataa
    14521 gcatgataca atagaggcat gctgaaggag gatcattgca agtatgaaga acaacataga
    14581 tgacatcaac ggatggctct atcacagaat acgtatgtgt atatggaaac agtggaagaa
    14641 accgaggaca aaggcacgta acctcatcaa gatgggagtg cccgaagact tggcaatgca
    14701 agcgggtaat acccgacgtg gacattggtt cgcaacgcat acagttgcaa taaacatggc
    14761 aatgacaaaa gaaaaactga taaacagtgg cttttatgat ttagccacag cctatcagtc
    14821 tgtgcacgtc aactattgaa accgccgtgt accgaacggt acgcacggtg gtgtgagagg
    14881 acggcggtta gtcaccgcat cctactcgat cagtcgacta aagaaaaaca ttttatagct
    14941 tttacctttt tccccggttg gcatactggt ggcaagtgct gcatggaatt gacctcactc
    15001 tgccggcggg aagctttacc gcactggtag gcccaagcgg cggcggaaaa tcgacaaccg
    15061 ccagactgat ctcgcggttc tgggatgtta cggaaggaaa cattaccatc ggcggtgtga
    15121 atatcaaaga catgtcgctg gagcagcttt cggagatggt cagctttgtg acgcaggata
    15181 acttcctgtt ccgatgctcc cttctggaaa acatccgact cggcaacccg gcggcatccg
    15241 atgaagaagt gcgggaggca gcaggaaagg cgtgctgcga agaatttatc gagaagctgc
    15301 cgatgggcta tgacacaccg gcgggcgagg caggaaagcg gctgtccggc ggagaaaaac
    15361 agcggattgc gattgcccac cggctcacca caatcgagca ggccgaccag attctcgtcg
    15421 tggatgacgg acagatcgtc cagaagggca cccacagaga gcttgcgtct gttccaggaa
    15481 aatatcagga ttttgtagaa atcagaagtc agtcggaagg ctggaagatt ggttaataag
    15541 tgtggcagat aatccattga gatcgtctgc cacatttttt gtcagttttc tgccggcaag
    15601 tcagagagca ggacatttcc gttgacggta cttgcctgaa tggtgaatgc agaaataccg
    15661 gagcgggtga atgtttttgt gtaggattcc gttcttccat tggagacgag gcggattttt
    15721 ccggttgtcg tggatgcatg aatggacgca tcggcaaggt cgtgcgggag atggagtttc
    15781 acggaaccgt tgacggattt tgctgtcagg tactcggaac aggttccc
//
