LOCUS       gnlProkkaCFHMEBGC_35    9093 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CFHMEBGC_35.
ACCESSION   gnlProkkaCFHMEBGC_35
VERSION     gnlProkkaCFHMEBGC_35
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:14:03
            Original ID  :: gnl|Prokka|CFHMEBGC_35
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9093
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9093
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7091:8528]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7092..8528
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..9093
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9093
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             215..1468
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 486.9; E-value: 5.3e-148)"
                     /gene_kind="other"
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="MARRKDSPQKAAMREMMRDYLKNNDISIKDGTDVNSIMRDMMSVL
                     LEGALDEELDEELGYSKYDYRNKETDNSRNGHSSKTMHTSYGDMDVAIPRDRNGDYEHQ
                     LIKKYQNTVTQDMEEKILSMYAKGMTTGDIESHMRELYDIDISDSTISRITDKILPIVK
                     EWQERPLEEVYAVVFMDAIHYHVRSEGRIVKRAVYIALGIDMNGRKDVLGMYVGENESA
                     KFWLSIMNGLKNRGVEDILIACVDGLNGFPQAIEAVYPKTEIQQCIIHQIRNSTKFVSY
                     KDIKKLMADLKLVYAAPTEEAALNELELFKDKWDSKYPKIYKSWHDNWATLSTYFKYPE
                     AVRRLIYTTNAIEGFNRQLWKVTKSKTVFPSDDSLLKMLYLATMDITKKWTGHRQDWGQ
                     IHSQLEIYFEERLIGRNL"
     CDS             complement(1684..2007)
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="MYYDIVKSGERINGLRTARRMTRQQLAEHIGLSVDALRKIETGVN
                     GAKIDTLVSIADVFEVSLDYLVSGSERKTDTDSLLAGLKENEIQFIRNMVLNAIDNMKL
                     LIE"
     CDS             complement(2182..2526)
                     /locus_tag="ctg35_3"
                     /transl_table=11
                     /translation="MGNREHIYEIIAGNIRKERKRFGMTQAELAERADISLDTIKSVEN
                     GRRAMSLDTYLNIVHALESSPMVLMSRKHPQKHIERFAFMTNRRDEREIEFALHMVEQL
                     LRGQDNYLNE"
     CDS             complement(2663..4378)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 266; E-value: 1.2e-80)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_4"
                     /transl_table=11
                     /translation="MRNKEAVKKLLGLLKDYRKIIALIIACLLISTGLNMCIPLLNRGI
                     MDYGFIGGDKELLIKQVICSLLIYMIIAVIDIIKEKKRVDISANIQYFLSEQSFKHLMK
                     IKADYFTNRNYAEILNNINVDIGNMTSIADEGVFFVVTQAFSMVGGIIGLFILDYRMTL
                     MVLLFIPVKAVIMKHFAKKRKRIMDEFITESEKYAGWFGDTVGGVREVKLFGIQENKRA
                     EFADRQLSVINKQKKMNMLAQWNGITDNIIVHLLTSLIYIIGANLVFDMQLSVGSVFAF
                     ITYSAYVTGPISAILNIGYLLSGIIPSTKRYYEFMALEEEKENEEGMTEPCFGDLELQN
                     LSFSYEKDKAVLSDINIAFPKGSKTVLIGRNGSGKSTLISLLLQLYQPTGGKITLNGID
                     ISEFVLREYRNMVSVVSQEIYLFNSSIRDNICMYKNIDDKFIMEACKDSGLADFISEVS
                     LDYVVGQNGAMLSGGQKQKIALARALVHNSPVIIFDEATSNTDVYSEHQINGLLHTKLK
                     EKTVIIITHKQEILKEADQIIMLKDGAVVGSGVYDDLSKDNLEFKNMLKMGEKY"
     CDS             complement(4368..5750)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 71.6; E-value: 1.2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_5"
                     /sec_met_domain="Peptidase_S8 (E-value: 6.2e-16, bitscore:
                     47.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLKIAVLDNGVDEKLLALCGLPDIIQQNKGNISDEEDLFLHGT
                     NCAMIIGLNCADAELYSYKLLDNTGKGNVDDLKSAFDWCLMNNIRLVNLSFGTTHFKDK
                     GIIRQLVNQYANKGLIIIAATANSGYTAFPASFSNVIGVKAKDTFNIDAEGLRDKGVDF
                     AAPSEHKIWFGGNDITLQKSNSYAAPYVTAMAGRLMMEQSWINNVWQIKKHLYQKFRGK
                     CVQYIPDWIEKGWIAGKVLKSKAEVYFEVAAKEEADTVILYDKNEFNEYREKHIVYLGN
                     EIAEQPDTQCFFWSRRNRKEQILCSRIKKESINIPVILIKSDKEQDQIWWLTELRKCFE
                     AEGYNAYAISTEQESVLYDLEYIPFAVDEDISNKIGDFLYWQTYYNQSDLIICGIQEKE
                     SIGVEADIFVRIENGKKQTGIQIYCDKIKKTQMCFGTLGEQQIKKVYDCLLTILTEDED
                     EE"
     CDS             complement(5743..6015)
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="MEKEAIEKWIEEYIENTIHITVDKKISLLDPRNGMLPRDLLQLYF
                     AVESYFGIKFEERNVIDERFDYLCNMVDAIQEKLKKIRTEINTYE"
     CDS             complement(6027..7088)
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="MNVVIYPYSIEHSYIKEYKKLFRYNIIYFMCYGNILPINHQNDND
                     DYCTFTDLVDGKISFDDFDTFCIIDKVPDENELYKIVEFVCSNGKNIICVEEEYLDQIE
                     KICKRYNVKLLQCNYETIETPEKKWNYDSEIIGIDIPVVAVMGIGQNVQKFDLQLYLRS
                     RFIDKGYKVSQIGTKKISGLFGLHPLPDFLFNTQYSDVDKVYAFNRVMKDVSMQEKPDV
                     ILLGIPDSLLPLNNKHRFSFGLYAYEIFNAVQPDFVITSLMANDGYNDEFYSEISKMAK
                     YKYNVNIDAYFVSQFCPLSNSIWSEKLSYVYLPQMELPKTEYKVYTTSDLNNDILFKQA
                     EKKLLLYGKYEQY"
     CDS             complement(7092..8528)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_8"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     7.6e-15, bitscore: 44.6, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.5e-13, bitscore: 39.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.3e-09, bitscore:
                     27.9, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKSKPNIHILELYNRYYMYDAGTNAIFSITKEMCRFLMAILNSN
                     GEIEVGDELKEEIEYLKESGCLKPVDEKIVVEHGEISLLESLYENNLNTIILQVTQNCN
                     LRCQYCVYSGSYINRVHNNKRMSVEVAKQAIDFLVKHSENSKEISIGFYGGEPLLEVPL
                     IREVVDYAEGVFSGKKLLFNMTTNATLLNIETAKYLYEKKFNVTISLDGPKATHDSNRI
                     FANSNKGTFDAVMQNLELIRKELPGFIKNIGFNAVIDLKQNVACSSEFFLNYETVKGIN
                     VASNYINPISKKDEEPINPELIAISYYEIFKTYLYACNKEIFSNYKPTLYSSEVASLKQ
                     IVKDRFVGLQTYQGKISPGGQCLPGIQRFFVTVDGKFFPCERVDEESSELCIGDLKNGF
                     DLENAKKILNVAKITEKECRECWCYKMCSQCVAKAGENGKIEAANRLKWCKQSRENAEE
                     YIKNYIVLKNFGCKFEEGEA"
     CDS             complement(8610..8804)
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MKLGKKNAMETGTFMAYACSCNCWCACTCNNCQSIGSANGKQVAS
                     NTQTSTTQVKSKGSLLLLA"
     CDS             complement(8855..9091)
                     /locus_tag="ctg35_10"
                     /transl_table=11
                     /translation="MCKVLSVTDTINGYDSITEEVLVTDEVDPGTEKARKELEERLEKR
                     KEEKRAEEKKRSSKDLVSDSDNELRIYSFDQKI"
ORIGIN
        1 ctcacaaaaa gtgtataccg gatcggaaat atcgatcaat ttttcgattt ctaatggtaa
       61 tttcagctga cgcatagtat aattaccatt ggtattgtta tttagtagca taattaatta
      121 taccaaaaaa tcgctcagac cgggagtatc ctaaagtttg tgtaaacctc caaactgatg
      181 taagataaaa ttactcagtt tggaggttat ttttatggca agaagaaaag acagcccaca
      241 aaaagcagca atgagagaaa tgatgcgtga ctatctgaaa aataatgata tcagcatcaa
      301 agatggtacc gatgtaaata gcatcatgcg tgacatgatg tctgtccttt tggaaggtgc
      361 tttggatgaa gaactggatg aggaattagg atattccaag tatgactacc gaaacaaaga
      421 aacagacaac agcagaaacg gtcattccag caaaaccatg cacaccagtt atggagatat
      481 ggatgtggcg attccaaggg atcgtaacgg tgattatgaa catcagctga ttaaaaaata
      541 tcaaaatacc gtaactcagg acatggaaga aaaaatactt tccatgtatg ccaagggaat
      601 gacaactgga gacattgaat cccacatgcg tgaattatac gatattgata tttctgacag
      661 tacaatcagc cggatcacag acaaaatcct gcctattgta aaagaatggc aggaacgccc
      721 gttagaagaa gtgtatgctg tcgtatttat ggatgccatc cactatcatg tccgcagtga
      781 agggcgcatt gtaaaacgtg ctgtctacat tgcccttggt atcgatatga atggaagaaa
      841 agatgttctc ggtatgtatg tcggagaaaa cgaaagtgcc aagttctggc tctccatcat
      901 gaatggactg aagaatcgag gagttgagga tatcctgatt gcatgtgtgg atggactaaa
      961 tggatttccg caggcaattg aagctgttta tccaaaaaca gaaatccagc aatgtatcat
     1021 tcatcagatc cgtaattcga cgaaatttgt ttcgtataaa gatatcaaaa aactaatggc
     1081 tgatctgaag cttgtatatg cggctccaac ggaagaagca gctttaaatg agttagaatt
     1141 gttcaaagat aaatgggatt ccaagtaccc gaaaatctat aaatcttggc atgataactg
     1201 ggcaacactg tccacttatt tcaaatatcc ggaggcagta agacggctga tttataccac
     1261 aaatgccatt gaaggattca atcgtcagct ctggaaagtg accaaaagca agacagtttt
     1321 tccgtcagat gatagccttt taaaaatgct gtatctggca actatggata tcacgaaaaa
     1381 atggaccgga cacaggcagg actggggaca gatccattcc cagctggaaa tctattttga
     1441 agaacgtcta atcggacgca acctgtaaaa acagcttgtt ttaggcaggt tttattgaca
     1501 tgcccaaaaa ctcctgtata atgcagatat gggcagaatc cggaaaatcg gctctgccca
     1561 tttgtaacta ttcacaaatc ttatatcagt ttttaacgtt tacacaaaac ttgaaacggt
     1621 ctcctcagac ctcacggtct gggcgatttt tctgtcaggg gagttttttt acagccccaa
     1681 tttttattct atcagaagtt tcatgttatc aatggcattt aacaccatat tccggataaa
     1741 ctgtatttca ttctctttca agcctgccag cagactgtct gtgtctgttt ttctttcact
     1801 tccacttaca agataatcca acgatacctc aaacacatcc gcaatactga ccagagtatc
     1861 tatctttgct ccatttacac cagtttcaat tttccgcaga gcatccactg acaatccaat
     1921 atgctcagca agctgctgtc ttgtcatcct tcgtgctgtc cgcagtccat ttattctttc
     1981 accactctta acaatatcgt aatacacctt tcactctttt ccggcacctt atgtatttgc
     2041 tcaagctgta tgtattgtac cgtaagagaa acctttgaca gagtgactga acccgctatt
     2101 tcaggtggaa cattgtacac cgattttttc tcactttact ttcctgttgg aatataataa
     2161 aaaggcagaa caaccacctt cctactcatt cagatagttg tcctgccctc ttaataactg
     2221 ttccaccata tgtaaagcaa attctatttc tctttcgtca cgccgattcg tcataaatgc
     2281 aaaacgctca atatgctttt gcggatgttt ccggctcatc aataccatcg gtgatgattc
     2341 cagtgcatgt acgatattta gatatgtgtc aaggctcatt gcccgtctgc cattttccac
     2401 actttttatc gtatccagcg atatgtctgc cctctctgca agttccgcct gtgtcattcc
     2461 aaacctttta cgttcttttc tgatattccc agcaataatt tcatatatat gctctctgtt
     2521 ccccataatc ccatcatcct ttctgactta tcgcattata tcagaaatta ttatggtgtc
     2581 tggcaatctg taaccatttg ccattttcgt gtaatacttt gcagatttta ctatctcctg
     2641 tcaattcatg gcaatgtatt attcaatatt tttctcccat tttcagcata tttttaaatt
     2701 ccagattatc ttttgacaaa tcatcataga ctccacttcc aacaacagca ccatctttca
     2761 gcataataat ctgatctgct tcttttaata tctcctgttt gtgggtaatg attatgaccg
     2821 tcttttcttt cagtttcgta tggagcagtc cgttaatctg atgttcagaa tacacatctg
     2881 tattagatgt ggcttcatca aatataataa ccggactgtt atgcaccaat gcccttgcca
     2941 gtgcaatttt ctgtttctgt cctccggaaa gcattgcccc attctgtcct accacataat
     3001 ccaatgacac ctcagaaata aaatcagcaa gtccactatc tttacaggct tccataatga
     3061 acttatcatc tatattttta tacatacaga tattatccct gatagatgaa ttgaacagat
     3121 agatctcctg gcttactaca gataccatat ttctgtattc tctcaaaaca aactccgaaa
     3181 tatctatacc atttaatgtt atttttccgc ctgtaggttg gtataattgc agcaacagac
     3241 ttatcagtgt actttttccc gaaccattcc gaccaatcag caccgtttta cttccctttg
     3301 gaaaagcaat attaatatcg gacagtaccg ctttatcctt ttcatatgaa aaagaaagat
     3361 tctgtaattc cagatcaccg aagcaaggct cggtcatgcc ctcctcattt tccttttctt
     3421 cttcaagtgc cataaactca taataccgct ttgttgaagg aataattcct gacaaaagat
     3481 acccgatatt gagtattgct gaaataggtc ctgtcacata cgcactatat gtaataaacg
     3541 caaacacact gcctactgaa agctgcatat caaaaacaag atttgcgcca ataatatata
     3601 tcaagctggt cagcagatgt acgataatgt tatccgttat gccgttccac tgggcaagca
     3661 tattcatctt tttctgttta ttgattacag aaagctgtct gtcagcaaat tcggctctct
     3721 tattttcctg tattccaaaa agctttactt cccttacacc gccaacagta tctccaaacc
     3781 atccggcata tttttcgctt tctgtaataa actcgtccat gattcttttt cgcttctttg
     3841 caaaatgttt cataataacc gcttttaccg gaataaaaag aagtaccatg agtgtcattc
     3901 tgtaatccag gataaaaagc ccgatgattc cacctaccat actgaatgcc tgagtgacaa
     3961 caaaaaacac accctcatct gcaatagaag tcatgttgcc tatatccaca tttatgttat
     4021 ttaggatttc cgcataattt ctattggtga aataatccgc ttttattttc atcagatgct
     4081 taaacgactg ttccgataaa aaatattgta tattcgcaga tatatctacc cgtttctttt
     4141 cttttataat atctataact gctataatca tataaataag caatgagcat attacctgtt
     4201 ttataagcag ttctttgtct ccgcctatga aaccatagtc cataatccct cggtttaata
     4261 acggaataca catattcaat cccgttgaaa tgagcagaca tgcaataatc agtgcaatta
     4321 tttttctata atcctttagc agccccagca gtttctttac tgcttcttta ttcctcatct
     4381 tcatcctccg tcaggattgt aagcaaacaa tcatatactt tctttatctg ctgctctccg
     4441 agggttccaa aacacatctg cgtctttttt attttgtcgc aataaatttg tattcctgtc
     4501 tgcttcttcc cattttctat tcttacaaat atatcggctt ccacaccgat actttctttt
     4561 tcctgtattc cacaaataat caaatcagac tggttgtaat aagtctgcca atacaggaaa
     4621 tcaccaatct tattacttat atcttcatca acagcaaaag ggatatattc taaatcatac
     4681 aatacgctct cctgttcagt ggaaatagca tacgcattat agccctctgc ttcaaaacac
     4741 tttcttaatt ccgtaagcca ccatatctga tcctgctctt tatcactttt tataagtatg
     4801 acaggtatat tgatgctctc cttctttatc cttgaacata agatctgttc ttttctgttt
     4861 cttctgctcc agaaaaagca ctgtgtatcc ggctgctctg ctatttcatt gccaagatac
     4921 acaatgtgct tctccctgta ttcattaaac tcatttttat catacaaaat tacagtgtct
     4981 gcttcttcct ttgcagctac ctcaaaataa acctctgcct tactctttaa tacctttccg
     5041 gcaatccatc ctttttctat ccaatccgga atatattgta cacattttcc cctgaatttc
     5101 tggtataaat gcttcttaat ctgccataca ttattgatcc atgactgttc catcattaac
     5161 cttccagcca ttgctgttac ataaggtgcc gcatagctgt tacttttctg aagcgttata
     5221 tcgtttcctc caaaccagat tttgtgttcc gatggagctg caaaatccac acctttatcc
     5281 cgcaaacctt ccgcatcaat gttaaatgta tcttttgctt ttactccgat aacatttgaa
     5341 aaggatgccg ggaaagccgt atacccactg ttagcagttg ccgcaattat gataagtccc
     5401 ttattggcat attgatttac caactgccga attattcctt tgtccttaaa atgtgtagtt
     5461 ccaaaactca gattgacaag tcttatattg ttcatcagac accagtcaaa cgctgatttc
     5521 agatcatcca catttccttt tcctgtatta tcaagcagtt tataactgta taattctgcg
     5581 tcggcacaat taagccctat gatcatggca caatttgtcc catgcagaaa caaatcctcc
     5641 tcatcactga tatttccttt gttctgctga attatatcgg gtaatccaca taatgcaagc
     5701 aatttttcgt ctacaccatt atctaatact gcaatcttta atttattcat aggtatttat
     5761 ctcagttcta atctttttta atttttcctg tattgcatca accatattgc ataaataatc
     5821 aaatctttca tctatgacat ttcgttcttc aaattttatt ccaaaataac tctcaacagc
     5881 aaaataaagc tgtaataaat ctcttggtaa cattccattt ctcggatcaa gtaaactgat
     5941 ttttttatcc actgtgatat ggattgtatt ttcaatatat tcttcaatcc atttttctat
     6001 tgcttccttt tccatcactt tctcctttaa tactgttcat attttccata taataataac
     6061 tttttttctg cctgtttgaa taaaatatca ttatttaagt cgctggttgt ataaacctta
     6121 tactctgttt taggaagttc catctgcggc aaatatacat aactcaattt ttctgaccag
     6181 attgaattag acaacggaca gaattgtgaa acaaaataag catctatatt tacattatat
     6241 ttatactttg ccatttttga aatttcagaa taaaattcat cattatatcc atcattagcc
     6301 atcagcgatg ttatgacaaa atctggttga accgcattaa atatttcata cgcatacaat
     6361 ccaaagctaa aacgatgctt attatttaat ggaagtaatg agtctggaat tcctaacaga
     6421 ataacatctg gtttttcctg catagaaaca tccttcataa ctctgttaaa cgcatacact
     6481 ttatcaacat ctgaatattg tgtattaaat aaaaagtctg gcaatggatg taaaccaaac
     6541 agtccactta ttttttttgt ccctatctga cttactttat agcccttgtc aataaatcta
     6601 cttctaagat acagttgtaa atcaaatttt tgcacattct gaccaattcc cattactgca
     6661 acaaccggta tatcaatccc tattatctct gaatcatagt tccatttttt ttcaggtgtt
     6721 tctattgttt cataattgca ttgcaacaat ttcacattgt acctcttgca aattttttca
     6781 atctgatcaa gatattcttc ttctacgcat atgatatttt ttccattaga acatacaaat
     6841 tccactattt tatatagttc attttcatct ggaactttgt caataatgca aaaagtgtca
     6901 aaatcatcaa aactaatttt tccgtccacc aaatcagtaa aagtacagta atcatcatta
     6961 tcattttgat gatttatcgg taaaatatta ccataacaca taaaatagat aatattgtat
     7021 ctaaataatt ttttatactc tttaatatag ctatgttcaa tcgaatatgg ataaataaca
     7081 acattcatct cttatgcttc tccttcctca aatttacagc caaaattttt taggacaata
     7141 taatttttta tgtattcttc tgcattttct ctcgattgtt tgcaccattt caaacgattg
     7201 gcagcttcta tctttccatt ctcgccagct tttgccacac attgagaaca cattttgtag
     7261 caccaacatt ccctgcattc tttttccgtt atcttcgcca cattcaaaat ttttttcgca
     7321 ttttctaaat caaatccatt ttttagatca cctatacata attcactcga ctcctcatct
     7381 actctttcac atggaaaaaa ttttccgtcc actgtaacaa agaaacgctg tatacctggc
     7441 agacattgtc ctcccggact gattttcccc tgatatgttt gcaatccgac aaatctatct
     7501 ttaacaattt gcttcaacga tgctacttcg ctactatata aagtcggctt ataattcgaa
     7561 aaaatttcct tattgcaagc atataaatat gttttaaata tttcataata tgatatggct
     7621 attagttcag gattaatcgg ctcttcatcc ttcttgctaa tcggatttat ataatttgaa
     7681 gccacattta ttcccttaac agtttcataa ttcaaaaaaa attcacttga gcaagccaca
     7741 ttttgcttta aatctatcac agcattaaat cctatatttt ttataaatcc cggtaattct
     7801 ttccttatca attccaaatt ctgcattacc gcatcaaatg tccctttatt gctgttagcg
     7861 aatatacgat tactgtcatg tgttgctttt ggtccgtcta aacttattgt aacattaaat
     7921 tttttctcat aaagatactt tgccgtttcg atatttaata aagtggcatt tgtcgtcata
     7981 ttaaaaagaa gttttttccc actaaacacc ccctctgcat aatctaccac ttctcttatc
     8041 agtggaactt ccagcaacgg ctctccacca taaaatccaa tggatatttc tttgctattt
     8101 tctgaatgtt ttaccaaaaa atcaatagcc tgcttagcaa cttcgactga cattctctta
     8161 ttgttatgta ccctgtttat ataacttcct gaataaacac aatattgaca tctcaagttg
     8221 cagttttgtg taacctgcaa aataatggta tttaaattat tttcatataa actttccaat
     8281 aaagatattt ccccatgttc aacgactatt ttttcatcaa ccggtttcag gcagcctgat
     8341 tcttttaaat attcaatttc ttcttttaat tcatcaccaa cttcgatttc tccattacta
     8401 ttcaaaatag ccataagaaa cctacacatt tcttttgtaa tagaaaatat agcgtttgtt
     8461 ccagcatcat acatataata cctgttgtat agttctaaaa tatgtatatt aggttttgat
     8521 ttagtcatat atacttctcc ttgcgtaaat agtgcaacag ggctttactg aacacagtaa
     8581 agccctacct tgttgaaata attcatgttc taagcaagta gcaataaaga acctttgctt
     8641 ttaacttgcg tagttgaagt ctgagtatta gatgctacct gttttccatt tgcacttcca
     8701 atactctggc agttgttaca agtacaagca caccagcaat tgcatgaaca agcatatgcc
     8761 ataaatgtac ccgtttccat tgcattcttc tttccaagct tcattatgtt tccctccttc
     8821 cttgcttttt tatatagaaa tgctaattgc atcactatat cttttgatca aaactatata
     8881 ttcttagttc attatctgaa tcagacacta aatcttttga acttcttttc ttttcctctg
     8941 ctctcttttc ctctttcctt ttctcgagtc tttcttcaag ttctttcctt gctttttctg
     9001 ttcccggatc aacctcatct gttaccagta cttcttctgt tatgctatca tatccattta
     9061 ttgtatccgt tacactcagt accttacagc cac
//
