LOCUS       c00001_gnlPro..        23228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CFHMEBGC_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 16:18:05
            Original ID  :: gnl|Prokka|CFHMEBGC_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 711444
            Orig. end    :: 734672
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23228
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[721444:724672]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23228
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23228
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(511..2250)
                     /locus_tag="ctg1_663"
                     /transl_table=11
                     /translation="MALDGIFLRHIKSEIEKEALGARVSQIYQPNREELVFGLRTFSGN
                     KKLLLSARANSPRVNFCSSTPENPAQPPMFCMLLRKRIGGGKLVGLRQNGCDRVLMLDF
                     ECVNELGDTVMITVVCEIMGMYSNIIIVDSNGVIIDSLKRVDLTMSSKRLVLPNIKYEL
                     PESQNKLNLLKCSVLDVCTAVKNLDTEMPLNKALLRTIEGVSPIVCREIEYKVMEGATN
                     RIEGVLFDRLAVEIEKLKSVCSDCSGKPVVVYREDGKPMDFCFMNVEQYGDFAKVESKE
                     SFSDLLDGFYEARDSRDRMRVKSQSLTKLLNNTLERLARKIAKQKSELERCADREHLRI
                     CGDLLQANIYRIERGAEYVDVENFYDENNAILRIKLNPAISPSANAQKYYKDYRKAKNA
                     EIMLKEQLEKGREELDYIDSVLDTVDRAENEKDLAQIREELTEQGYLKVQKGKKPRQTT
                     LPPLEFESSDGFKILVGRNNRQNDKLTLKTASKNDMWLHTKDIHGSHVIVVSDGKEISD
                     TAIYEAARLAAYHSKARNSSQVPVDYTLVRYVSKPNGSKPGMVIYVNNKTLYVKPSQTV
                     EKQ"
     CDS             complement(2265..2750)
                     /locus_tag="ctg1_664"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIIELSEERIK
                     SNIPNRSQIDEVIFSEGKRIMQKISPSDYVVAMCIEGKPMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSRMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             complement(2772..3560)
                     /locus_tag="ctg1_665"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSASEGVLIDAGRSCKQIENAMLANGL
                     DMGSIGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRIDTPHDAAESCCYRVTAPDGKSALIATDMGVMLPDVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSVSTTKAIIF"
     CDS             complement(3683..4975)
                     /locus_tag="ctg1_666"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDSLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     IRMGAQISVEGRLAIIEGGVPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRGLGADIKKVYFTGDNEQELGA"
     CDS             5705..6022
                     /locus_tag="ctg1_667"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             6035..8359
                     /locus_tag="ctg1_668"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETNGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKIAETDD
                     FEDVSFNFATKLLNFKSEKQNPVSEIQSICDSIEDGVTVVDKTPKNDITTKAEPEITKK
                     KINHDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFVATLLSGYKVFIKGAKNI
                     LKLRIDETTLMAVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDGAEQVVPAESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPV
                     DAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASV
                     YTPVVVLIAVAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIREKANGLELPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEQKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKALGVENTVMLTGDRQQPAENVKNE
                     LGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVIIAARLLKKKY"
     CDS             8559..9803
                     /locus_tag="ctg1_669"
                     /transl_table=11
                     /translation="LKKIFLLLVTALFLLSLYGCNTSSSSNNPTEQTTVTDTDDLSLDS
                     DTDSETEFNYDLEIYYNDKKIDNLNLFDALMPTEDGLIYSKINETSPNEIEYYRYYLDK
                     KNSVKLGSIKNWSMQINDKAYVNNHLCFMASTGDITDEENRTLEFIDIDLNKNKMTTVF
                     SDKGGFPYDTITGADNLVIITKVLNNGTSLELYDTETQKFKQLKYLEFDDKNSIGETIR
                     KVSIDKSTKTISLLVLDCISQNEASLKIETYDYDMNFLKSYDISNISDDSNELIQGVQV
                     FDFKNNYLFYQNFSITRCIGYIDSDKLKKSDISEDVDDTFSIVSASEDDSDTNLLYKRA
                     ESSSENNYIYLFDTTNKTMKETKFNIEEKGYTIGGISRIGKDNLMIMMSPDNTDEKSNL
                     NPRIYFTKLSDLNFQ"
     CDS             10001..11623
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_670"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-41, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             11636..12127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_671"
                     /sec_met_domain="ALS_ss_C (E-value: 1.7e-28, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             12188..13228
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_672"
                     /sec_met_domain="IlvN (E-value: 4.3e-82, bitscore: 269.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 6e-59, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLR
                     DSGCDVIVGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(13530..15104)
                     /locus_tag="ctg1_673"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWNKVNGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCITSDAKKFTSGYNPTGKSVKYVATPKISKLEVTYDGVKLTWNKVAGAEKYRV
                     YYKDRNGWTKLADTTGTTMLDMNVVSKEFDLSIDDIYYTVRCISKDAKSFTSGYDSKGT
                     PIGNHQDCPEIYSIGAVNNGVEMHWTGDAPKFRVYIKENGSWKRIAETYDNYYVHKGAK
                     SGSNTYTVRGVSKDGKKFTTMFNPTGVTYRYKTSDKTRDAYINYMMNHTDEWMPSLGSN
                     HNLSGVMFLDFDFDGVPELVAQKADSNEYSFHSVVYKFEDGKLKRVGNVNDGFAIYYNK
                     TAKKYEVHDLKISLNVDDGYYWSGNSIITYDGETLFANMYSARGVGEESNNNIYYSYFD
                     GNDKNISRAKYNEINLKQFNNCVNAHMFTQFIATGYGDNSVWGENTTAENKQSLLDAYN
                     SFSYEKY"
     CDS             complement(15539..17680)
                     /locus_tag="ctg1_674"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWNKVSGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGKSVKYIAAPEISKLENVNGGVKITWNKVNGASKYRI
                     YHKNSSDWFRVSDTTSNSIVDKSVGMGTYTYTVRCISDDGKSFESGFNPKGSSIRYIQA
                     PKILETNVVNGGIKVIWDSEENTNYRLYCKTEGKGWTKVCDSKTGVVTHKNLQPNKTYT
                     YTVRAISSDAKKYLSGYDPVGMSAKYVATPKISKAEYTYDGIKLAWNKVAGAEKYRVYY
                     KDATGWNKLADTTGNSYLDMGLVSRELSIKDNSVNGQYIYTVRCISSNGKVFQSGYDTK
                     GSKANLGNECPEIVRVDSMHGGITVSWTDVCEDNSKYRIYVKEKGSWKKLADTTNNYYT
                     HKNVKAGQTYTYTVRCVSKDGKKFTSIYNPSGVTFKYKTTDKTRDAYIDYLLKHESEWL
                     PELKVGNVALAGVQFADLDFDGVPELIVQEAGDKEYYLNAKVYTFKDGKFSLVGFDDYR
                     TYIPNQLTYFYDKSAKKYIINAVELSTSNVDRYLERENYTLNYDGTVLVVRGYSSAHLA
                     LESRGLEYHYYNNTGRTTKQAYNATNVSVLGNCVNAHMYSQFVCCSVDGYPKLWNNYSE
                     TQKKQHLLDSYNAFSYDKY"
     CDS             complement(17877..18890)
                     /locus_tag="ctg1_675"
                     /transl_table=11
                     /translation="MKKLLTALIAFVMCFSVVTTAFAATPDETSDPDLISDIKQVMIDT
                     YYGDEKPDFIEVRIYGTASDGGVYFDFMDSFTHWTDEVEFDIGDYTISYPSDCPVMLYK
                     NNKVYTLSDAYETGAIDDDMLYELYTWGNLWGKMDIIQKGEDRALLSEIKRVIINKYYN
                     GKAPEYLNVEIVGSTSDETVCFRNIPFMSLGVMIEQTIGDYTYYYNHGDDVMLYKNGNV
                     YSIKEAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTSVATVDESVTVPDTTSA
                     TKPVSTSDTATNDTPNNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRNYFK"
     CDS             complement(19084..20091)
                     /locus_tag="ctg1_676"
                     /transl_table=11
                     /translation="MKKFLTALIAFVMCFSVVTTAFAATPDEASDSDLISDIKQAMLDT
                     YYGDEKPEYLNVEILLDDEDEVYFSFSDSFATSANRVYTEAGNYIVSYLENCPVALYKN
                     NRVYMIPDAYNSGVIDDDTLEGLTYCGHMDIVPKSDDSALVIEIKNKVIEECFDGKSPE
                     TLRIDIVGRTSDGGVYFKHSVGGGIDVMVEETIGDYTYSYTHGDDVMLYKNGNVYSIKE
                     AYESGVIDDSILEELSKMNFGLKSNKPNTTVPTEPTTTVATVDEPVTVPDTTSATSATK
                     PVSTSDTATNDTPNNSQNNSGAVQTGQNSVAVILLVAMLAGCGVIFAKRRNHFE"
     CDS             complement(20286..21689)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_677"
                     /sec_met_domain="HMGL-like (E-value: 9.6e-48, bitscore:
                     159.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 8.8e-54, bitscore:
                     178.5, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKIRVTETALRDAHQSLIATRMTTEEMLPVLDKLDKIGYYSLE
                     CWGGATYDSCLRFLNEDPWDRLRTIREHCPNTKLQMLFRGQNMLGYRHYADDCVEYLVQ
                     RSIANGIDIIRIFDALNDIKNLKTAIKAANKEGGHAQVAISYTTGPVFTDEYYVEYAKR
                     IADAGADSICIKDMAALLTPTRTESLVKAIKAAVPELPLQLHTHYTSGLASMCLLKGVE
                     AGADGIDTAISPLALGTSHAPTESMVAALSGTEFDTGLDLKQFSDIRAYFMTLREKYIK
                     SGLLDPKMLATDANALIYQVPGGMLSNLLSQLKQAGKEDKLDEVLAEVPRVRKDSGYPP
                     LVTPTSQIVGTQAVFNVITGKRYSMCTNEFKGLVAGEYGTTPMPIDPEFQKKIIGDKKI
                     IKGRPADQLKPELDKLRGEIEQWIEQPEDVLSYAQFPKVALDFFEKRRNAKVGINGDKL
                     DKKNMVHPV"
     CDS             complement(21720..22085)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.7; E-value:
                     8.2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_678"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.6e-19, bitscore:
                     65.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRITVNGTAYDVQVEELGGSSAPAAAAPAPAAAPAPAAKPAA
                     PAGAQGSVVVKAPMPGTVVNVVVSAGQAVKAGDDLVFIEAMKMETPVKAPQDGTVATVD
                     VAKGESVDSGKVLVTLN"
ORIGIN
        1 ggttttgtta agtcttatgt gtcagtacat tcctatgggc aaggtcagcg acagggagtt
       61 ttcacgaatt aaccgtaaaa tcacacgcag agaatatgac aaggtaaagc ttgaaatgat
      121 gcgactggga attgacggct ttacacagga gctttcttcc gcagatgaaa gctatgtccc
      181 cgaatgggat tttgaaggat gattttgtca gttcggtcat ctgaattcct cttcattttt
      241 caattggtat tgtttacttg gtattattct cttagtcttt ttctatgggt attattaggc
      301 ttcaaattct gaagtagtcc ccttcaaaat ctgaaggggg cgggttcaaa ttctgaaggg
      361 ggcaggtgca aattctgaag ggtatgagtt caaattctgc acccctaaaa tacgaatttt
      421 tacattcgat tttaccgccc gttaaaaaca attaaattaa cataaaaacg gagagcgtct
      481 tgccctccgt ttaattttta ttaaaatatc ttactgcttt tcaaccgttt gtgacggttt
      541 tacatacagg gttttgttgt tgacataaat caccataccc ggttttgagc cgtttggctt
      601 tgacacatag cgaacaagtg tgtagtcaac gggaacctga ctgctgtttc tcgccttact
      661 gtgatatgcc gcaagccgtg ccgcctcgta gattgccgtg tcggaaatct ctttgccgtc
      721 cgaaacaaca attacatgag aaccgtgaat gtcctttgta tgcaaccaca tatcgttctt
      781 tgatgctgtt ttcaaagtca gcttatcgtt ctggcggttg tttcttccta caaggatttt
      841 aaaaccgtcg cttgattcaa attcgagcgg cggcaaagtt gtctgacggg gctttttgcc
      901 cttttgaacc ttgagatagc cctgctcggt aagttcctca cgaatttgcg caaggtcttt
      961 ttcattctcc gcacggtcaa ccgtatcgag aacggagtct atataatcaa gctcttctct
     1021 gcccttttca agctgttctt tgagcataat ttcggcattt ttagccttgc ggtaatcctt
     1081 gtaatacttc tgggcatttg ccgaaggtga gattgccgga ttaagcttta tgcgtaaaat
     1141 tgcgttgttc tcatcgtaaa agttttcaac atcaacatac tccgcaccac gctcaatgcg
     1201 atagatattt gcctgtaaaa ggtcaccgca tatgcgaaga tgctcacggt ctgcacagcg
     1261 ttcaagctca ctcttctgct ttgcaatttt tcgtgcaagt ctttcaagtg tgttgttcaa
     1321 aagctttgta aggctttgtg atttcaccct cattctgtca cgactgtcac gagcctcata
     1381 gaatccgtca agcaaatcgg agaagctttc cttactctca acctttgcaa aatcgccgta
     1441 ctgctcaaca ttcataaagc agaagtccat aggcttgccg tcctcacgat aaaccacaac
     1501 aggcttgccc gaacaatcgc tgcaaacgct tttcagcttt tcaatttcaa ctgcgagtcg
     1561 gtcaaaaagc acaccctcaa ttctgtttgt tgcgccctcc ataaccttgt attcaatctc
     1621 acggcataca atcggagaaa cgccctcaat tgtccttaac agcgccttgt taagcggcat
     1681 ttccgtgtca agatttttta cggctgtaca cacatcaagc accgaacatt taagcagatt
     1741 cagcttgttc tgcgattcgg gaagttcgta ttttatattc ggcagtacaa gtcttttact
     1801 gctcattgta agatctacac gcttgagtga atcaatgatg acgccgtttg aatcaacaat
     1861 aattatgttg ctgtacatac ccataatttc gcatacaaca gttatcatca cagtatcacc
     1921 gagttcgttc acgcactcga aatcgagcat aagaacacgg tcgcaaccgt tctggcgaag
     1981 tcccacaagc tttccgccgc cgattctttt tcgcaaaagc atacagaaca tcggaggttg
     2041 tgcaggattt tcgggtgttg acgaacagaa gttcactctc ggtgaatttg ctcgtgcaga
     2101 aagcaacagc tttttgttgc cggaaaatgt tctcagcccg aacacaagct cctctctgtt
     2161 cggctgataa atctgcgaca cccttgcacc gagagcctct ttttctattt cacttttaat
     2221 atgtcttaaa aaaattccgt caagcgccat agtaactccg taaattattt gtgatattta
     2281 ccgtttgatg aaatttcaaa cgcacggtaa atctgttcgc ttaaaatcat tcttgccatt
     2341 tggtgaggga aggtcattct gctcattgaa agacggacat ccgcccgttt tttaaccgat
     2401 tcgtcaagcc cgtagctgcc gccgataata aaatcaacgg tgctttttcc gcttacggac
     2461 gcattgtcaa tcagctttga aagctcctcg ctcgacatag gctttccctc aatacacatt
     2521 gcaacaacat aatccgaagg cgaaattttc tgcatgattc gttttccctc agagaaaata
     2581 acctcatcaa tctgcgacct attcggtatg ttgctcttaa tgcgttcttc cgaaagctca
     2641 ataatattga atttacaaaa tgcggtcaag cgttttgcat actctgcaat tgcgtcggta
     2701 aaatattttt ctttgatttt gccgatacaa attatgttaa tcttaatcat atttctcttg
     2761 tttgtttaag gttaaaagat gatggctttt gttgtgctta cactcggagc aacatcaagc
     2821 gaataatcgc ttttgtactt cattccgttt gatgtgagca ggtctacgga tgtcgacatt
     2881 gcaagcggaa cggtattatt ttcttcgctg agatggccga gcataagtct taaagttccc
     2941 ttttcaacaa ggttaacaag ttcttttgca catgcctcat ttgaaagatg tcctctgttt
     3001 gaaaggattc tctgctttag cggataagga taaaatccgt ttttgagcat attaatatcg
     3061 tgatttgact caagcacaac aaagtcgctc tgctctgcgg cagttctgac atcgggcaac
     3121 ataacgccca tatcggttgc tataagtgcg gattttccgt cgggagcagt aacacggtaa
     3181 caacagcttt ccgccgcatc gtggggggtg tcaattcgct gaacacgcat attgccgatt
     3241 acaacctcgt cagttataac atctgcatcc gtgtttggat caagcttatt acctgccctc
     3301 aaagcattga gcgtaccaag acttgaatat accttaaagc cgtaacgctt tgcaagcaca
     3361 cgcaaggcac tgcaatggtc agtgtgttcg tgagttataa aaaccgcccc gatactgccc
     3421 atatcaagtc cgtttgcaag catggcattt tcaatctgct tgcatgaacg acctgcgtca
     3481 atcagtacgc cttcgcttgc cgaacctatg tagtagctgt tacccttact tccgctgaac
     3541 agcggtactg ctcttgccaa aacaatcaat ccttatcttt agtataacga atatgataac
     3601 acaaatttta aaatttgtaa attatctcac aaaaaagccg ttctcacaaa gaaaacggct
     3661 ttgatttcta attaaatttt agtcaggcac cgagctcttg ctcgttgtct cctgtaaaat
     3721 acaccttttt gatatctgca ccaagtcctc tgaacttttc aacaacatct tcatatccac
     3781 gctcaatgaa ctgaatattt gaaatctctg ttgtaccgtt aatttcaaga gcggcaataa
     3841 tcatagccgc acctgcacga aggtcggttg ccttaacggg agccgctgtg agcggaacac
     3901 cgccctcaat gattgcaagt ctgccctcaa cagaaatctg cgcacccatt ctgataagct
     3961 cgctgacata ctggtagcga ttatcccaaa cattctcgtt gatgatgctt gttccgggaa
     4021 cgctcataag caatgcggca aactgcggct gacagtctgt cgggaagccg ggatgcggca
     4081 ttgtcttgat attacagcgc tttagcggag cagatgacgc atcaaccttg agagcttcat
     4141 catattccgt aatcttaaca cccatctcac gcagctttgc gctgattgat tcaagatgct
     4201 tcggtgtaat attctttacc gtaatacaac ctcttgttgc ggcggcggca cacatatatg
     4261 ttcctgcctc aatctggtcg ggaataatcg aataagtaat gccgtgaaga tactcaacgc
     4321 cacggatttt gataacatcc gtacctgcgc ccctgacatc cgcacccatt gaattaagga
     4381 agttcgcaag gtcaacaata tgcggttctc ttgcggcatt ttcaataatg gtctgtccct
     4441 ttgcctttga tgcggcaagc ataatgttca ttgttgcacc aacggacaca acatcaaggt
     4501 acacatgtgt accgacaagg ctgtcgcatt ctgcctctat aatcgcaccg tcaacaagct
     4561 gagttgtcgc accgagagcc tcaaagcctt taagatgctg gtcaatcgga cgcacgccaa
     4621 agttacagcc gcccggaaga gccaccttag ccttgccgta cttgcccaaa agtgcgccga
     4681 ggagataata tgacgctctc atacctctta caaggtcggt cacagcattg catgtgcgga
     4741 tttttgtagg atcaatatat aaggacgaac ggttgattcg tcttacatta gcacccatct
     4801 gctgaagaat tctgctgata agtgatacat cgctgatgtt aggaatattt tcaatctggc
     4861 acggttcatc acaaagaata actgccggaa taattgcaac ggctgcattt ttcgcaccgc
     4921 tgattgtcac ttcacccgat aatggctttc cgccggtaac tacgaacttc tccaattgtt
     4981 acaccccaat taatgtgtag aagatacttt taactaaata agctaaatat ctgaaaatgt
     5041 atatctatat agtgtataag taaaaatcaa aaattatacg aatctaaaat tcataatgag
     5101 aactaatttg ttacatttta ttaaaaacga acccactcgg ttacgcagat gtaatttaac
     5161 aattctctta cagaaaatga tactacaaaa ttgtattaaa gtcaacggaa taataaaact
     5221 gtaatctatt tttgggcaag ttgtactcaa attattaatt tgttgctttt tttgttttta
     5281 atataaccaa ccatgctttt taaaaccgtt ttttcctaaa aagaagtaat taattaaagc
     5341 aattttttgt aaaattatta caaattgaaa caagtgttat tttcgtgtta tcatcaaaca
     5401 tctgagtatt ttccaattca aattgaacac agaaaaatat cgttccgtta ttcctatgat
     5461 aattttacac cttcaatctt cttttttcaa atttaaaatt aactttctat actatatata
     5521 ctttccaaac ggacacaata aacaggtgaa actttggggc aaaaaaactt gaaaaacatt
     5581 acattttttc gtgtgtgtct attgactttt taaaaaggga atgctatatt ataattaaca
     5641 tatgagcata tcttcatatg ttcaagtata actattaacc tgagagaaaa ttaaggggac
     5701 gcctatggaa aacaaagaaa aaacaaccac tcccgaaatg cccgacattg atgtgctgtt
     5761 tgagcttgca gaccttttta aggttttcgg tgattcaacc cgacttcgca ttatgtacac
     5821 catttcggaa aatgaaatgt cggtgctcaa cattgctgaa gctctcagca tggagcaaag
     5881 cacaatttcc caccaactgc gtgtgttaag gcagaacaag ctggtgcgtg ttcgccgtga
     5941 aggaaagcag atttattaca gccttgacga tgaccatgtg aaacgaatca tcgaaatggg
     6001 acttgaccat gtccttgaat aaggagggag acatatgagg tacaaatatc agcttgataa
     6061 tctcaactgc gctcattgtg caggcaagat tgaggctaaa attgcagaaa caaacggctt
     6121 tgaagatgtg agctttaatt ttgcgacaaa acttctcaac ttcaaaagcg aaaagcagaa
     6181 tcctgtttcc gaaattcagg caatttgcga cagcattgag gacggtgtaa ccgttgttga
     6241 caaaactccg aaaaccaatc tcaaaaaata cacctacact ttagacaatc tcaattgtgc
     6301 tcattgtgcg ggcaaaattg aggctaaaat tgcagaaaca gacgactttg aggatgtaag
     6361 ctttaatttt gcgacaaaac ttctcaactt caaaagcgaa aagcagaatc ctgtttccga
     6421 aattcagtcg atctgcgaca gcattgagga cggtgtaact gttgttgaca aaactccgaa
     6481 aaatgatatc acaacaaagg cagaacccga aatcacgaaa aagaaaatca accatgacac
     6541 aatcttcctt gcaatttcaa ttgtacttgc tgtagtgtcc gaaattctcc accttacact
     6601 tgacggtgtt acggctgttc attatgttgt actcgcagcg tgttttgttg caacacttct
     6661 ttcgggttac aaggtattta tcaagggtgc aaaaaacatt ctaaagctga gaattgacga
     6721 aacaacgctt atggctgttg cggtaattgc ggcattctgt cttggagatt ttgttgaggc
     6781 ggcaatggta acaatcctct tttctatcgg tgaaattttt gaggatcgag cagttgacgc
     6841 atcccgccgt gacattgaaa agcttgcaaa cattcgtccc gatacagcaa caattattgt
     6901 tgacggtgca gaacaggttg ttcctgccga aagcgttgaa atcggaagta tcattgaagt
     6961 caagccatac gaaagagttc cgcttgacgg cattattatc aaaggtaaaa cgactctcga
     7021 cacatcggct ctcacaggcg aaagccttcc tgttgatgca ggcgagggca gtgaggtact
     7081 cagcggcgca atcaacggca gtaaccttat tactgtcaaa accacaaagc atttcggcga
     7141 cagtaccgca acaagaattc ttcagcttgt tgaagatgcc gccgctcaaa agggcaacag
     7201 cgaaaagctt atttcaagat ttgcctctgt ttacacaccg gttgttgtac tcattgcagt
     7261 tgcaatcgca gtaattcctc cgctttgcgg actcggagca ttcagcgaat ggctataccg
     7321 tgcgcttgtt tgtcttgtag cgtcatgtcc gtgtgctatt gttatttccg tacctctctc
     7381 ctactattcg ggtatcggtg cggcatccga agtcggtgta ctcatcaagg gtggaaaata
     7441 tattgaggct cttgcgaaag cagacacatt cgtattcgat aaaacaggca cgctcacaag
     7501 tggcaagctc agcgtaaaca aggttaatac tgtcggttca tacagtgctg acgaagttct
     7561 tgctcttgcc gctgcaagcg aaaaatattc cgctcatccg attgcatccg caatcagaga
     7621 aaaggcaaac ggtcttgaac ttcccgagct ttccgactac agcgaaagtg ccggtcacgg
     7681 aacaagcgca gtttataacg gcaaaactat tcagtgcggc ggttcaaaga ttctttcgga
     7741 cgaacagaag aagattgcaa ataaagacga ttctgttttc gtaatttatg acggtcagct
     7801 tatcggttcg ctcaatgtca gcgacacagt aagacctgag gcaaaagagg ttatctcaca
     7861 gcttaaagcg ctcggtgtcg agaacacggt aatgctcaca ggcgacagac aacagcctgc
     7921 cgaaaatgtt aaaaacgaac tcggactttc cgaatgtcac gcagaacttc tccctgctca
     7981 aaagcttgag cttttcaagg gcttgaaatc aaaatccaag ggtgcttgct ttgtaggcga
     8041 cggcatcaat gatgcccctg ttctttcggc aagcgactgc ggtatcgcaa tgggattcgg
     8101 cagtgaagcc gctattgaag cgtcagacgc agttctcgca tcaggcacac tcaaacagct
     8161 tccaaaggca attaaaattg caagaagtgt tatcaacacc gtcaaaggca acatcatctt
     8221 tgccctctca atcaaggctc ttgtaattat cctcgccgca ttcggtcttg cacaaatctg
     8281 gatgtccgtt atcgccgaca caggcgtcag cgtagtctgc gtcatcatag ccgcaagact
     8341 cctcaaaaag aaatattgat tttttttgca aatcatatca tttattatga taaagcaccg
     8401 tgagctttca caagtttcac ggtgctttca tttgccaaaa tttttctaaa cataatctta
     8461 tattatagta ttttaaaatc attgactttt ataattatat aaattataat gtttttgtca
     8521 gtgcttgtaa ctgataaata aacttcggag agattaattt gaaaaagata tttttattat
     8581 tagtaaccgc tttattttta ctttcattat atggatgtaa cacttcttca tcaagcaata
     8641 accccactga acaaacaacc gtaacggata cagatgattt atctcttgat tcagatacag
     8701 attctgaaac agaatttaat tacgatttgg agatttacta taacgataaa aagattgata
     8761 atttaaatct tttcgatgca cttatgccaa ctgaggatgg actcatatat tcaaaaatca
     8821 acgaaacttc tccgaatgaa atagaatact acagatatta tttagataaa aaaaacagtg
     8881 taaaacttgg ttcaataaaa aactggtcta tgcaaattaa cgataaagcg tatgtaaata
     8941 atcacttatg ttttatggca agcacgggtg acattacaga cgaagaaaac agaacccttg
     9001 aatttattga tatagacctt aataaaaaca aaatgactac tgtcttttct gacaaaggcg
     9061 gttttcccta tgataccatt acaggtgcag acaatcttgt cataattaca aaagtattaa
     9121 acaacggtac ttctttggaa ctgtatgaca ccgaaacgca aaagtttaaa caactgaaat
     9181 atttagagtt tgatgataaa aacagtatcg gggaaactat aagaaaagtt tcaattgaca
     9241 aaagtacaaa aacaatctct cttttggttt tggattgcat ttcacagaac gaagcttctt
     9301 taaaaataga aacttatgac tatgatatga attttctcaa aagctatgat atatccaaca
     9361 tttcagatga ttcaaacgaa ttaattcagg gcgtacaggt ttttgatttt aaaaacaatt
     9421 atctattcta tcaaaatttc agcataacaa gatgtatagg atatatagac agcgataagc
     9481 tgaaaaaatc cgacatatca gaagatgtag atgatacttt ttcaatagta tccgcatctg
     9541 aagatgacag tgatacaaat ttattgtata agagggcgga atcaagttca gaaaataact
     9601 acatatatct ttttgataca accaacaaaa caatgaaaga aacaaaattt aatattgaag
     9661 aaaaagggta cactataggc ggtatatcac ggataggaaa agataatttg atgataatga
     9721 tgtcccctga taatacagat gaaaaaagca accttaatcc aagaatatac tttacaaaac
     9781 taagcgactt aaattttcag taaacaggcg gtaaaaatca attaaaatcc attttgcaaa
     9841 ttatctgtca aaatcctgca aaaaatttaa tttatgggca atactgctct ttacttttta
     9901 aggtatttat tgtataatta gcggtaaagc aaaaaggtat atttattgtt acaaaacacc
     9961 ttttgctcac aataaataag gataggaggg acaaaacata atgatcagcg gtgctgaaat
    10021 tatggtaaaa tgtttggaag ccgagggcgt tgacatagtc tttggttatc ccggtgcggc
    10081 tatctgccca ttttacgata aagtttacga ttcgagcatt acccacattc ttgttcgtca
    10141 ggaacagaac gctgctcatg cggcaagcgg ctatgcaaga tgcagtaatc gtcccggtgt
    10201 ttgcgtggca acttccggtc ccggtgcaac caacctcatc acaggcattg caaccgccta
    10261 tacggactct attccgattg ttgccattac aggtcaggtt cgttccgacc ttctcggcag
    10321 agatgtcttt caggaagctg acatcacggg agcttgtgaa ccgtttgtaa agcacagtta
    10381 tctcgtcagc aaaacagaag accttccgag agttttcaaa gaggctttcc atattgcctc
    10441 aaccggcaga cccggtcctg tacttatcga cattcccgtt gatattcagg aaaatgaaat
    10501 tgaaagtttt gaatatcccg aaagcgtaaa cattatcggt tacaagccga atactaaggg
    10561 acacgcaatt caggttaaaa aggctgttga ggccatcaac gcaagcaagc gtcctgttat
    10621 cgtatcaggc ggcggcgtgc tgagttcggg tatcaagctt aagcttcaaa aatttgcaga
    10681 aactacgggt atccccgtta tttcaactat gatgggcatc ggtgttatgc ccagcgagca
    10741 tgagctttat ctcggaatgc tcggcactca cggcaaggct gttgccaacc gtgctcttca
    10801 cgaagccgac cttgtaatcg tatgcggtgc aagactcggt gacagagctg ttgcggctcc
    10861 cgaccagatg agtgaaaaca caaaggtaat tcacattgac attgaccctg ctgaaatcgg
    10921 taagaatgtt aaaacagaaa ttccgattgt aggcgatatg aaaaatgtca tcaatatgct
    10981 gcttgacagc atcggcgatt acaaggttac aacaatgtgg agcgaaaccg taaagaactg
    11041 gaaaaaagac ctttaccgtg agcctcccgt ttttgacggc tttgttgagc cgagaacact
    11101 tgtcggtcat ctcagtgcaa tgttccgctc gaaggcaatt cttgttgccg atgtaggaca
    11161 aaatcaaatc tggtgtgcaa acaacttccg tattcgtgag ggcagattcc tcacaacagg
    11221 cggtatgggt acaatgggtt actcaattcc cgctgcaatc ggtgcaaagt ttgcaagacc
    11281 cgaccgtgat gttattgtaa tctgcggtga cggcagtttt cagatggggc ttaatgagct
    11341 tgcgactatt gcaggcaatc agctcggaat taaaatcatc attatgaaaa acgcacgact
    11401 cggaatggtt cgtgaacttc aggacaaaca ctacggcggc agacactccg caacaattct
    11461 caacggtgat cccgacttct tgaagattgc cgatgcttac ggcattgacc atgcagaggc
    11521 tcattcaaac aaggaagccg aaaacatcat caagggtatt gttgattcgg aaaaaccgtt
    11581 cattcttgtt tgcgatgttc accccgacac tccgtcaatt taatgaggtg ataaaatgca
    11641 gtatacatta tcaatacttg ttgaaaatca ggcgggcgtt ctttcaaaga tttcgggact
    11701 tttctctcgc cgaggtttta acatcgactc acttgcagta ggtgttactc aggacccgtc
    11761 ggtttcccga atcacaatcg ttgcaaacgg tgacgagtac attgttgaac agcttgaaaa
    11821 acagctcaac aagctcattc ccgttattaa ggtaaaaagg cttaacgagg gcgaatttat
    11881 cagccgtgag cttgttttaa tcaaggttca ttgcgccgcc tcaaaaagag ccgaaattgt
    11941 caaaacggtt gaaattatgc aggcgaaaat cgttgatgta tccccttcgt cagttaccgt
    12001 tgagtactgc gaatgtgcaa gccgcatcaa cacgcttgtt gacttactca agccttatgg
    12061 tatccgtgag attgtaagaa caggtactgt tgccatcgac agaggcacag cttcggtttc
    12121 cgtttaatct tacagttagc atatatttta atttatatgc cgcgtttgcg gtaaggagga
    12181 ctttaatatg aaagactaca caaaaaacat gacagcacca atctactatc agtcagattg
    12241 caaccttgac cttctcaagg gtaagaaaat tgctattatc ggttacggca gccagggtca
    12301 tgcacacgct ctcaacctca gggattcagg ttgtgatgta atcgtcggtc tttacaaagg
    12361 cagcaagagc tgggcaaagg ctgaggcaca gggctttaag gtatatacat cagcagaggc
    12421 tgcaaagcag gctgacatca tcatgattct tatcaacgat gaaaagcagg cagctcttta
    12481 caagaacgac atcgagccaa acctcgaagc aggcaatatg cttatgttcg ctcacggctt
    12541 taacattcac ttcggttgca tcaagcctcc aaaggatgtt gatgttacaa tggtagctcc
    12601 taagggacct ggccacacag ttcgttcaga gtatcaggtt ggtaagggtg taccttgcct
    12661 cgttgctgtt gaacaggatg ctacaggtca ggctaaggat ctcgcacttg catatgcact
    12721 cggtatcggc ggtgcaagag ccggcgttct tgaaacaaca ttcagaacag aaacagaaac
    12781 agacctcttc ggtgaacagg ctgttctttg cggcggtgtt tgtgcactta tgcaggcagg
    12841 ttttgaaaca ctttgcgatg ccggttacga cccaagaaat gcttactttg agtgtatcca
    12901 tgagatgaag ctcatcgttg accttatcta tcagtcaggt tttgcaggca tgagatattc
    12961 aatctctaac acagctgagt acggtgacta catcacaggt ccaaagatca tcacagagga
    13021 tactaagaag gctatgagaa aggttctttc tgacattcag gacggtacat ttgctaagga
    13081 cttcctcctt gacatgagcg atgccggttc acaggttcac ttcaaggcta tgagaaagct
    13141 cgctgccgaa gctcctgccg aagtattcgg taaggaagtt agaaagctct atagctggtc
    13201 tgacgaagat aagctcatca acaactaatg cgagtgtctc gcacacagtt cgtgaagaca
    13261 gtttgatgta ttcaaacttc tgtcacccga gcattacata gtacgaattt agggtagctt
    13321 gattttcaag ctaccctttt tgcgagtacc tcgctcgtag ttcgtgtagg tagtttgtga
    13381 taatttacaa ctacttattc ccaagcttaa catagtacag attaacggtt cagtcaattt
    13441 ggctgaaccg ttttttgttg tgcaataaaa gggttcagct ttttacggct gaaccctttt
    13501 gcagttaaaa cttattaatt tttaaataat caatacttct cataggagaa agaattataa
    13561 gcgtcaagca aagactgctt attctcagcg gtagtgttct caccccatac gctgttatca
    13621 ccataacctg tcgcaataaa ttgggtaaac atatgtgcat ttacgcaatt attaaactgt
    13681 ttaaggttaa tttcgttata ttttgcccgt gaaatatttt tgtcattacc gtcaaaataa
    13741 ctataataaa tattattatt tgattcttcg cctacgcctc ttgccgaata catatttgca
    13801 aaaagagtct ctccgtcgta tgtgattatt gaattacccg accaatagta accgtcatct
    13861 acatttaaag atatctttag gtcgtgaacc tcatactttt tggcagtttt attatagtat
    13921 atcgcaaaac cgtcgttaac atttcccact ctttttaact taccgtcttc aaatttgtaa
    13981 acaacggaat ggaaactata ctcattggaa tcagcctttt gtgcaacaag ctccggaact
    14041 ccgtcaaagt cgaaatccaa aaacataaca cctgacaaat tgtgattact tcccaagctt
    14101 ggcatccatt catcggtatg attcatcata tagttgatat aagcgtccct tgttttatcg
    14161 gatgtcttat atctgtatgt tacaccggtt gggttaaaca tcgtagtaaa ctttttaccg
    14221 tcttttgaaa cacctcttac tgtgtaagtg ttactgccgg actttgcacc cttgtgaaca
    14281 taatagttgt cataagtttc tgctatcctc ttccaagaac cgttttcttt aatataaaca
    14341 cggaactttg gcgcatctcc cgtccaatgc atttcaacac cgttgtttac tgcaccaatg
    14401 ctgtaaattt cgggacaatc ctgatgattg ccaataggcg taccctttga atcgtagccg
    14461 cttgtaaaac tcttggcatc cttgctgata caacgaaccg tgtaataaat atcatcaata
    14521 cttaaatcaa attcctttga aacaacattc atatcaagca tagtcgtgcc tgttgtatcg
    14581 gcaagctttg tccaaccgtt tctgtccttg tagtacacac gatacttctc tgcacctgca
    14641 accttgttcc atgtcagctt tacaccgtca tatgtaacct caagttttga aattttcggt
    14701 gtggcaacat actttaccga cttgcctgtc gggttataac cgcttgtaaa tttctttgcg
    14761 tctgatgtaa tgcatctaac cgtataggtg taatttctgc cggatgaaac atccttgtcg
    14821 atatatgagg ttgaagttgt atcgaccatt cgtgtccagc ctttacggcc cttgtagtaa
    14881 actctgtatt tagccgcacc gttcactttg ttccatgtaa gctttacacc gccgtaaacg
    14941 ctttcagcct ttgaaatttt cggagttgcc aagcttgccc ttgcaacctg tgcatactgc
    15001 acgggtgtgt taagcggttc aaccgcattt gcagaaactg ccgaaaccgc aaccgcagac
    15061 atcgacatta ccgccgccat agctataggt aaaaactttt tcatatctat ccctcgcttt
    15121 gttcaaattc tatgcattat taaaaacttt cgctaaattt ttatgcaagt taattgtaac
    15181 attaaatgat ataaaaagca atacatcttg ataaactatc acaaattttt taagctaaaa
    15241 taaataaacc gctctcaata acgagaacgg cttttattat gtcaaagcat atgagcatca
    15301 acataaaatt tcatcaaaca ggcggataat atccgcctct acagaattgt tcaaatggta
    15361 gttatattac gctcgggcat aaatattttt tatttgtcaa acttctgtca ccagagcgtt
    15421 gtatagtacg aattaacggt tcagccaatt tggctgaacc gttttttgtt gtgcaataaa
    15481 agggttcagc tttttacggc taaacccttt tgtagttaaa acttattaat tttgacaatc
    15541 aatatttgtc gtaagaaaaa gcgttatatg aatcaagaag gtgctgtttc ttctgtgttt
    15601 cactataatt attccaaagt tttggatagc cgtcaacaga acagcaaaca aactgactgt
    15661 acatatgtgc atttacacaa ttaccgagta cactcacatt tgtggcatta tatgcctgtt
    15721 ttgttgttct tccggtatta ttgtaataat ggtattccaa tccccgactt tcaagagcca
    15781 aatgagcaga agagtatcca cgaacaacca aaactgtgcc gtcataattc aatgtatagt
    15841 tttcgcgttc aagataacgg tcaacatttg aggttgacaa ttcaacggca ttaattatat
    15901 atttcttagc agatttgtca tagaaataag tcagttgatt cggtatataa gttctataat
    15961 catcaaatcc gactaacgag aactttccgt ccttaaaggt atacaccttt gcattcaaat
    16021 agtattcctt atctcctgcc tcctgtacta taagctcggg aacaccgtca aaatcgagat
    16081 cggcaaactg cacaccggcc aaagcaacat ttcctacctt gagttcaggt aaccattccg
    16141 attcatgctt gagcagataa tctatgtatg catctcttgt tttatctgta gtcttatact
    16201 taaatgtcac acctgacgga ttatagatac ttgtaaattt cttgccgtcc ttagaaacac
    16261 atcttacggt ataagtgtag gtctgtcctg cttttacatt tttatgagtg taataattat
    16321 ttgttgtatc agcaagcttt ttccacgaac ctttttcttt tacataaata cgatactttg
    16381 aattatcttc gcaaacatct gtccatgaaa ctgtaattcc gccatgcatt gagtcaacac
    16441 gaacaatctc cggacattca ttgcctaaat tcgccttaga accttttgta tcataaccgc
    16501 tctggaaaac cttgccgtta cttgaaatgc aacgaacagt ataaatatac tgaccgttta
    16561 cggaattatc ttttatgctt agttctcttg atacaagtcc catatcaaga taactgttac
    16621 ccgttgtatc ggcaagtttg ttccaaccgg tagcatcctt ataatataca cgatattttt
    16681 cagcacctgc aaccttattc cacgcaagct tgataccgtc atatgtatat tctgcctttg
    16741 atattttcgg tgtggcaaca tattttgcgc tcattcccac agggtcataa ccgctcaaat
    16801 actttttagc gtcggaactg attgctctta cagtgtatgt ataggtctta ttcggctgta
    16861 aatttttatg tgtcacaaca cctgttttgc tatcgcatac ttttgtccag cccttacctt
    16921 ctgttttgca gtacaatctg taatttgtat tttcttcaga atcccaaatc accttaatac
    16981 cgccgtttac aacattggtt tcaagtattt taggagcttg aatatatctg atacttgagc
    17041 cttttgggtt aaatccactc tcaaaactct ttccgtcatc acttatacac ctcacggtat
    17101 aagtataggt tcccatacca acagatttat caactataga attagaagtc gtatctgata
    17161 ctctgaacca atctgacgaa tttttatgat aaattctata ctttgatgca ccgtttactt
    17221 tgttccatgt aattttcaca ccgccgttta cattttcaag ctttgaaatt tcgggggcgg
    17281 caatatattt tacacttttg ccctttgaat cataaccgct tgtaaagctc tttccgtcag
    17341 cagaaataca tcttacagta taggtgtaat tcctgcccga tgaaacatcc ttgtcgatat
    17401 atgaggttga agttgtatca accattcgtg tccaaccttt acggcccttg tagtaaactc
    17461 tgtacttagc cgcaccgctt actttgttcc atgtaagctt tacaccgccg taaacacttt
    17521 cggcttttga aattttcgga gtagccaagc ttgcccttgc aacctgtgca tactgcacgg
    17581 gtgtgttaag cggttcaacc gcatttgcag aaactgccga aaccgcaacc gcagacatcg
    17641 acattaccgc cgccatagct ataggtaaaa actttttcat atctatccct cactttgttc
    17701 aaattctacg cattattaaa aactttcgct gaatttttat gcaagttaat tgtaacatta
    17761 aatgatataa aaagcaatac atcttgataa actatcacaa atttttaagc taaaataaat
    17821 aaaccgttca caaaagcgag aacggtttat tttatatatt ctgttgatgt tttgaattat
    17881 ttaaaataat ttctgcgttt tgcaaaaatt actgcacaac ctgcaagcat tgcaacaaga
    17941 agaattacag caacgctgtt ctgtcctgtc tgtacagcac cgctgttatt ctgtgaattg
    18001 ttcggtgtgt catttgtagc tgtgtcgctt gttgaaacag gcttagttgc cgaagttgta
    18061 tcgggtactg ttacagattc gtcaactgtt gcaaccgaag ttgtaggctc agtaggaaca
    18121 gttgtattcg gtttattaga ttccaaacca aaattcattt ttgacaattc ttcaagaata
    18181 ctatcgtcaa taactccgct ttcataagcc tctttaattg agtaaacatt gccattctta
    18241 taaagcataa catcatcgcc atggttgtaa taataagtat agtcaccaat tgtttgttca
    18301 atcataacgc ctaaactcat aaagggtata tttctaaaac atactgtttc atcacttgta
    18361 gaaccaacaa tttcgacatt caaatattca ggtgctttgc cattgtaata tttatttata
    18421 attacacgct ttatttctga aaggagagct ctatcttcgc ccttttggat gatatccatc
    18481 tttccccaaa gatttcccca agtgtataat tcatagagca tatcatcatc aatcgcacct
    18541 gtttcatagg catctgacaa ggtatatact ttattatttt tatataacat aacaggacaa
    18601 tcgctcggat aagaaatagt ataatcacct atatcgaatt ccacttcatc tgtccagtgt
    18661 gtaaaactat ccataaaatc gaaatacacg ccaccgtcac tggctgtacc atatattctt
    18721 acttcaataa aatcaggctt ttcatcgcca taatatgtat ctatcatcac ctgtttaata
    18781 tctgaaatca agtctggatc agaagtttca tcaggtgtag cagcaaaagc tgttgttaca
    18841 accgaaaagc acattacaaa tgctatcaat gcagttaaaa gttttttcat ttttatttcc
    18901 tcatctttta tttattctat ctgtaataat ggtatacgca acagatattc aatttacatc
    18961 attataccgc taaaatatat gtaatgcaat atagttgcta aaaattcaca taaaataatc
    19021 agcaaaataa aaaccgttct caataacgag aacggctttt atagggatta tttaatttgt
    19081 aaattactca aaatgatttc tgcgttttgc aaaaatcaca ccgcaacctg caagcattgc
    19141 aacaagaaga attacagcaa cgctattctg tcctgtctgt acagcaccgc tgttgttctg
    19201 tgaattgttc ggtgtgtcat ttgtagctgt gtcgcttgtt gaaacaggct ttgttgccga
    19261 agttgcagaa gttgtatcgg gtactgttac aggttcgtca actgttgcaa ccgtagttgt
    19321 aggctcagta ggaacagttg tattcggttt attagatttc aaaccaaaat tcatttttga
    19381 caattcttca agaatactat cgtcaataac tccgctttca taagcctctt taattgagta
    19441 aacattgcca ttcttataaa gcataacatc atcgccgtga gtatagctgt aagtataatc
    19501 gccgattgtt tcttcaacca ttacatcaat accgccgcct acgctgtgtt taaaatatac
    19561 tccgccgtca cttgttctgc caacaatatc aattctcaaa gtttcaggtg atttgccgtc
    19621 aaaacactct tcaataactt tgttttttat ttcgataaca agtgctgaat catcgctttt
    19681 cggaactata tccatatgtc cgcaataggt caagccctca agtgtatcgt catcaataac
    19741 gcctgaatta taagcatcgg ggatcatata aaccctgttg tttttgtaca gtgccacagg
    19801 acaattttca aggtaagaaa ctatgtaatt gcctgcctcg gtgtaaactc tgtttgcaga
    19861 agtagcaaag ctgtcagaaa aactgaaata aacctcgtct tcatcgtcca aaagaatttc
    19921 gacattcaga tattcaggct tttcatcacc ataatatgta tctaacatag cctgtttaat
    19981 atctgaaatc aagtctgaat cagaagcttc atccggtgta gccgcaaaag ctgttgttac
    20041 aaccgaaaag cacattacaa atgctatcaa tgctgttaaa aattttttca tttttatttc
    20101 ctcatctttt atttattcta tctgtaataa tggtatatgc aacagatatt caatttacat
    20161 cattataccg ctaaaatata tgtaatgcaa tatagttgct aaaaatttag caagaataat
    20221 tctgcccaaa tgaaaatgcc actttcatag cgaaagtggc ataaatgtta attttagttg
    20281 tcaaatcaaa cagggtgaac catatttttc ttgtcaagct tgtcgccgtt gatgccaacc
    20341 ttggcatttc ttctcttttc aaagaagtcg agagcaacct tcgggaactg tgcataagaa
    20401 agaacatcct caggctgttc aatccactgc tcaatctcac cacggagctt atcaagctca
    20461 ggcttaagct gatctgcagg acgacctttg ataatcttct tgtcaccgat aatcttcttc
    20521 tgaaactcag gatcaatcgg cattggagtt gtaccatact caccggcaac aagtcccttg
    20581 aactcgtttg tgcacattga gtagcgcttg cctgtgatta cattgaatac agcctgtgtg
    20641 ccgacaatct gtgatgtcgg agtaacaagc ggaggataac ctgaatcctt acgaacacgg
    20701 ggtacttctg caagaacttc gtcaagcttg tcttctttac cggcctgctt gagctgtgaa
    20761 agaaggttgg aaagcatacc gccgggaacc tgatagataa gagcgttagc gtctgttgcg
    20821 agcatcttag gatcaagaag tcctgacttg atgtacttct cacgaagagt catgaagtaa
    20881 gcacggatgt cagagaactg tttaaggtca agacctgtgt cgaactctgt gcctgaaaga
    20941 gcggcaacca ttgactctgt aggtgcgtgt gatgtaccga gagcgagtgg gctgattgct
    21001 gtgtcaatgc cgtcggcacc tgcctcaaca ccctttaaaa gacacattga tgcaagacct
    21061 gatgtgtagt gggtgtggag ctgaagcgga agctccggaa cagcggcttt gatagccttt
    21121 acaaggcttt cggttcttgt cggagtaaga agagcagcca tatccttgat acagattgaa
    21181 tctgcacctg cgtctgcaat tctcttagca tactcaacat agtattcatc tgtgaatact
    21241 ggacctgttg tgtagctgat agcaacctgt gcatgaccgc cttctttgtt agcggccttg
    21301 atagctgttt taagattctt gatgtcgtta agagcatcaa aaatacggat aatgtcaata
    21361 ccgtttgcga ttgaacgctg aacaaggtac tcaacgcagt catcggcata gtgacgataa
    21421 ccgagcatat tctgtcctct gaaaagcatc tggagctttg tgttagggca atgctctctg
    21481 attgtgcgga gtctgtccca cggatcttcg tttaagaatc tgaggcatga gtcatatgtt
    21541 gcgccgcccc agcattcaag tgagtaataa ccgattttat cgagtttgtc aagaacaggg
    21601 agcatttcct ctgttgtcat tcttgttgca atgagtgact gatgagcgtc acgcagagca
    21661 gtttcggtaa ctctgatttt ttttgccatt ttacagcatc cctttctccg aattattgat
    21721 tagttaagtg ttacgagaac cttacctgag tcaactgact caccctttgc aacatcaact
    21781 gttgcaactg tgccgtcctg cggagcctta acgggagttt ccatcttcat agcctcgatg
    21841 aatacaaggt catctcctgc cttaacagcc tgtcctgccg aaacaacaac attaacaact
    21901 gtaccgggca taggagcctt tacaacaaca gaaccctgag cgcctgcggg agctgccggc
    21961 tttgctgcag gagcgggagc agctgccgga gcaggagcgg ctgctgcggg agctgaagag
    22021 ccaccgagtt cttcaacctg aacatcatat gctgtgccgt taactgtaat tcttaaattc
    22081 ttcattttta gtatcccctt ttattttaac aagtaatcat ttatcagata gttgaatgct
    22141 tctttgaaag tgttgaaaca cgcttgcccg agagcatatc aagagcagaa ataagagtct
    22201 gacggagctg aacttcttca acaataccgt caacatagcc gttctgagcg gcattgtaag
    22261 cagaaagatt ctcgtcagca aacttctgag caacctcagc ctgcttatct gtggcaacat
    22321 tcataacttc gggagccata atgaatgcgg cagcttcaac attaacaggt gaaataactg
    22381 catcgggaag tgcgtaaaca acatctgcat tagcgcctgt gcctgcaaga gcaacatagc
    22441 ctgaaccgat tgccttgcct gtaacaacag aaatcttgac tgttgttgcc tcagcataag
    22501 cggctgacgc ctttgttgcc gacttgattg actcaaagcc cgggcagttt acgaatgtta
    22561 caacagggag tgagaaagcg tcgcagaaac gaacaaactt tgctaccttg tttgcagact
    22621 tgcaaccaag ctcattgccc tttgtaacaa caatacctac aacctgaccg ccgagtcttg
    22681 caaaacgaac atttgcttcc ttgccgtaat cattgaagag ctttacaatg ctgttgccgt
    22741 caactgttct gctgactaca caaccgcaac cgtcctctgc cggagcttct tcaaatgact
    22801 gaggagccat tgtgaggtta tttgacggaa gataaaggat aagttccttt gcagccttga
    22861 ttgccttgtc tgcatcgtca caaacgattg aggcaatacc gttttcagca ttgtaagcgg
    22921 catcggaatg cttgcctgtt accgaaagtg aaagctgtgc gtctttgctc atgataacga
    22981 tgtctgcgct tgcggcgtta agagcgtttg ttccgaggca agtgccgaga acaaccgaga
    23041 tctgcggtac aacacccgaa agtgacgcag ccgcattgag aacatcaccg caacctgcga
    23101 gaagctctgt accctgatta agtctgccgc caacgctgtc atagaagcct acaacaggag
    23161 cgcctgtctt gagtgcaaga ccatacagct ttttaagctt ggcagcctgt gccttactca
    23221 tggcaccg
//
