LOCUS       c00043_gnlPro..        16329 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ANEBHBEJ_43.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:12:20
            Original ID  :: gnl|Prokka|ANEBHBEJ_43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2491
            Orig. end    :: 18820
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16329
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12491:15952]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13461
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16329
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16329
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             960..2534
                     /locus_tag="ctg43_4"
                     /transl_table=11
                     /translation="MKKNYERIVLLLLSALLSVGFLAGCNDADNGDDGYLLKKEDISVN
                     RPDGGFKALVNQPFRIEVKSVSDEGVSYEWSLGDSKIADSKNLEYTFTSLGTFTLTLHA
                     SQGTTTFDYDFEVKVTTDYVLKKEDITIEEPEGGFRAKVDQLFRIEVTSVSDDGVSYLW
                     FEDEEPVAQTKNLEHMFSHGGAIGLKLTASQGDIFFDYYFTVFVEYAPIDPPAEGANPY
                     ITKVFDYMPAVGQFTNTLPLYEEGDTQETMNHKVLDAIGNNKRGMITLGGFGGYVTVGF
                     DHTIQNVEGLRDFRVLGNAFYANANPNPDAPEGGSCEPGVIMVAYDPDNLGPDNVQWYE
                     IQGSAHVDPTKEPWYEMAKVNGNDVNIYFDYRITYYRPDSEPTSRDEWDTYIKWEDNQG
                     NSGYKMKNQYHSQPYYPLWAGNTLSFTGTCLPQNAIDESGSGTYFVLYKFRYGYADNEI
                     NSYDDSSIDISWAVDASGNSVNLPGVDYIKIYTGVNQENGWLGECSTEIMGVEDLHLLK
                     EEIHTRR"
     CDS             complement(3162..4985)
                     /locus_tag="ctg43_5"
                     /transl_table=11
                     /translation="MAETEKPDLKEQVALLPLSPGVYQFVDRSGTIIYVGKAKSLRKRV
                     SSYFVQSKEHSAKVRVLVKQIVEIRHIVVGSETDALLLENSLIKSLQPRYNILLKDDKT
                     YPWIVVRRERFPRVQSTRILTRDGSQYFGPYGSVMMQRSVLDFIREVIPLRTCKLNLAP
                     ELIAKDKYTVCLQYHLGNCKAPCVGRQSEEEYAQLVGMVVSVLKGDLRPVRQYLEGEMA
                     RAAGELKFELAQRYKQRLDALDNYAGRSVIVSAKIVDVDVFSLLPDDDVAWCNFVRIRH
                     GSVVGVQTVKLSTGVGGDERDMLTLAIQHIVENIAGGELSREVIVPLLPSTTLLFEGVT
                     FTVPKRGEKLELLEFSRKSARIYRAEQLKNLEIKNPERYTERLMNAVQKELRLDRQPRH
                     IECFDNSNLQGAHPVASCVVFRDGKPSRKEYRHFNIKTVTGADDYASMREVVFRRYTRL
                     MAEGAKMPDLIIADGGKGQMGVIHEVLERLGLDIPIAGLAKDDRHRTAELLCGFPPVLV
                     GIRPTSPLFHFLAHIQEEVHRFAVSFHRQKRSKTFIHSELEQIEGVGDKTVQTLLRHFR
                     TVEKVRAANIEELSALVGAAKAKKIRAFFEK"
     CDS             5108..6049
                     /locus_tag="ctg43_6"
                     /transl_table=11
                     /translation="MRKLILLLLSGMLSTACVDKDYDLGNIDTDNIAIGDEGSQFRIPL
                     VKVLVSKDEIKNNGGNIEEIFREADIWFPSQLPDGKFVDLVKLQDKDDQTYVNTLLRTL
                     REEMRTSDAKLASVVDLVWDKYAAEFLLLLNLTAPDEQTFKTAFKTAYRNDASLRERLA
                     DEVSALARTYLTGSLGIDQLEYEVGHIDISSDIVDMLADNLDPEGTPNARNTLFLYGQI
                     TSGLPLSLLLDPSFSPTEITFQVGVGADKASNDIPQTQLFAEDLRQIVEGITIRIPVTL
                     TEYYPGKGFSDDQYQIVISLSLLKNGGLKLDI"
     CDS             6063..7436
                     /locus_tag="ctg43_7"
                     /transl_table=11
                     /translation="MKKIYTLIAAALLATGAAAQNPTAYFMEGSTFRSQFNPAFAPLRG
                     YVNIPAIGGVNINVGGNIAVDNILFSRDGKLVTLLDSSVSAADALSGLKQNNLLGMDFR
                     MNVIGFGAFTKNHKNFWSFDLNVRVNEDANLPYSLFEFIKLGKEGQIRNFGTSTDSYLE
                     AAFSYSFPLMDDRLYIGIRGKFLAGLARAQVTYDRFDISLREDRWAVLTQGTLDLTAAG
                     AKVETDPDSETFEIGDLDFKPTKPAGYGFALDLGATYDILPNLQASLAVTDLGFISWSK
                     KNSVMGVSTQETEFTGATVPENASEPVPDFDLEMLKFNQVDGRSTTKMLHASVNAGLEY
                     EVWRHKIGIGLLYTARVWKYKTMHNITGSVNFHPVRWFTVSGSYSVVDNRGGAVGLALN
                     LCPNWINFYLATDVLTSKHTPQWVPIKQSSMNVTLGLGIPIGKRSHRIAAYVREGDRR"
     CDS             complement(7758..8606)
                     /locus_tag="ctg43_8"
                     /transl_table=11
                     /translation="MKKRRVALVLAGGGARGVAHIGAIEELERQGFEISAVAGTSMGAL
                     VGGVYASGYLEPFKEWMRALDKYKVFSLVDFALSTEGLVKGDRVMEAMKELVPDVQIER
                     MPVPFAAVAADLLTGDEVVLDSGGLYDAIRASISIPSVFRPVHRDGRVLVDGGTVNPLP
                     LNRVRREEGDLLVAVDVSARFGADSVRRANASLNYYKVLIASSQIMQQRITQLMCRLYK
                     PDIMVGLPADSYGMFEFYRSEEILEAGRAATRAALERLETDGENGMVFAESEEKIATAR
                     F"
     CDS             complement(8603..9331)
                     /locus_tag="ctg43_9"
                     /transl_table=11
                     /translation="MDAKEFASAYGEAFGPAAGLPLLFWYSDGPVRAVPKVEGCFFKAL
                     AEAREGSAVSLNAANIGCGGGKFYTGFAPMPPFVPAFVSQKEHYKQTPEMVLEFIGRLG
                     VPEASGAWLNFARIDTPQAAEAFGTADGALFFATPDILSGLVSWAVYDNNADDAVCAPF
                     GSGCSAVVTQAVRENRRGGRSVFLALFDPSVRPWVDASELGFVAPMSRLREMCGTMRAS
                     CLFGTHAWNKVRVRINGGNI"
     CDS             complement(9335..9868)
                     /locus_tag="ctg43_10"
                     /transl_table=11
                     /translation="MTKKELRAAMRRRNLGMDAAERAEASRRIFGRAGRLEAFGAARTV
                     GVFCSLPDEPDTAETLARWSAVKRIVVPRVEGDVMRFCEYDPQTLRPGAFGIAEPGPEA
                     QTCDPSEIDLVIVPGTAFTAAGARCGRGRGYYDKYLSRPDVHAVKVGVCFAHQLVGELP
                     AEPHDVAMDYIITD"
     CDS             10001..10696
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_11"
                     /sec_met_domain="SucD_FumR (E-value: 2.8e-70, bitscore:
                     226.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSCFLSNSSLGKKLVMSVTGMFLVLFILFHMSMNITAIISPEAYN
                     MICELLGANWYALAGTAVLALGVFVHFFYAVILTLNNYKARGSQRYAVTVQEPGVAWAS
                     KNMLVLGFIILGGLLIHLFNFWSKMQLVEILGGHENSLGLDPADGASLIAYTFSQWYYV
                     VIYLVWFAALWFHLTHGVWSMFQTVGWANDTWYPRLKCIANIVATIIFLGFAAVVLVYF
                     FCPCIAGAC"
     CDS             10733..12679
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 204.4; E-value:
                     1.1e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_12"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.1e-63, bitscore:
                     204.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.5e-44,
                     bitscore: 140.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLDAKIPAGALAEKWSNHKTAIKVVGPANKRKLDIIIVGTGL
                     GGASAAASLGELGYNVKVFCIQDSPRRAHSIAAQGGINAAKNYQNDNDSVYRLFYDTIK
                     GGDYRAREANVYRLAEVSNLIIDQCVGQGVPFAREYGGLLANRSFGGAQVSRTFYARGQ
                     TGQQLLLGAYAALNKEIAAGSVKSYPRHEMLDIVIEDGEAKGIIARNLVTGEIERHGAH
                     AVVIATGGYGNVFFLSTNAMASNGSAAFQCYRKGAGFANPCFTQIHPTCIPVHGDQQSK
                     LTLMSESLRNDGRIWVPKKLEDVKAIRAGKLKPSQIAEEDRDYYLERRYPAFGNLVPRD
                     VASRAAKERCDAGYGVNETGLAVYLDFKTAIERLGKDIIKQRYGNLFDMYEEITDVSPY
                     EQPMQIFPAVHYTMGGIWVDYNLMTTIPGLYAIGEANFSDHGANRLGASALMQGLADGY
                     FVLPYTIGDYLSHKIQAPKVKTDTKAFDEAEKGVKEKIAKLLAINGKQSVDDIHKKLGH
                     IMWENVGMARTKESLEKAITEIQALRKEFWKDVKVVGKENDFNVELEKALRLADFLELG
                     ELMARDALNREESCGGHFRTEHQTEEGEAKRDDENFVYAAVWEYKGMDQAPELTKEPLN
                     FEFVHPAQRNYKD"
     CDS             12718..13461
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_13"
                     /sec_met_domain="Fer2_3 (E-value: 2.9e-25, bitscore: 78.7,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.4e-12, bitscore: 38.3,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.1e-06, bitscore: 16.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTLKIWRQKDAKSKGAFESYKVENISADTSFLEMLDILNNNLI
                     HEGKEPVAFDHDCREGICGMCSLHIDGQAHGPSQGATTCQIYMRKFKDGATITIEPWRS
                     AAFPVIKDLVVNRSAYDQILQAGGFISVRTNSVPDANAIPISQADAEESMDAAACIGCG
                     ACAATCKNGSAMLFVAARVSSLAKLPQGRVEGARRAKAMVAKMDELGFGNCTNTGACQA
                     ECPKQISIAHIARLNREFLSAKFED"
     CDS             13795..14334
                     /locus_tag="ctg43_14"
                     /transl_table=11
                     /translation="MKETVNVNIGSVAFILDEDAYRVLGSYFDDIRRRLPEGDAETMGD
                     IEARVAEIFRERVASPMRVITLDVVRATMAQMGSPADFGEPRGAERSESAEEGTGTESA
                     EQPPLRKLYRSRTERSIAGICGGLAAYFDSDPTLIRLLMLLLILFGGLSIWAYIILWIV
                     IPEEPARKFNINSKNR"
     CDS             14339..14548
                     /locus_tag="ctg43_15"
                     /transl_table=11
                     /translation="MATNENRRLFRSQDSIIAGVCAGLAEFFGLDTSLVRIATLLLIFF
                     GGLSLWVYIILWLIVPKAPKRLNA"
     CDS             14553..14888
                     /locus_tag="ctg43_16"
                     /transl_table=11
                     /translation="MAEDNVKAQMRKGILEYCILAILSREDSYAPKIIAELKQAEMIVV
                     EGTLYPILTRQKNAGLLTYRWEESPQGPPRKYYTLTDKGREYLATLDEAWDELVGQIQL
                     IRHGKNN"
     CDS             14907..15701
                     /locus_tag="ctg43_17"
                     /transl_table=11
                     /translation="MKKLLLIAVLIAACLSATAYVACVAAPLLGKNIKGSGKIVTKTVP
                     APDFDGIEASRAVKVVISDKVSDIRIEADDNLIDLVVVRAVKGKLEATLDQKVNNIQNG
                     NVTITVPANGKIRSLDASSASKIIGETTLKAGKFSIEASSAAKIKAAVEAVSCTIETSS
                     ASKVEASVEAESCSLDASSASKIILEGSAGTFRADMSSASKLNAEKFSAVNASIDTSSA
                     ASASIDCSGKLTASASSGSSVRYSGDCQTSLEKSSGGSIRKL"
     CDS             15724..16329
                     /locus_tag="ctg43_18"
                     /transl_table=11
                     /translation="MKEVKKCSISGVAFTMDADAYEALETYLESLKTTYKDTADGAEIV
                     ADIEARIAELILSAQDNTRIVEKPLILNIIRQMGSAEDISRESVDRDLHCDTPRIPRRL
                     YRDTENAKLGGVCAGIGKYFDIDPVWVRLGLFLPLLFTCFGWIPFLHWFSPMFGNLFGI
                     FLICYFIMWFAVPAARSARQKLEMNGEKITAQSIGEVTA"
ORIGIN
        1 tatttacggc gaacgcaacc cttatgaggt caaagacctc ggcgacgtgg gaaacgacat
       61 tcaaatctac ggtgacaaac tctgggcggt tataaattgt tccaattatg tcgaggtaat
      121 ggatgtcaat acagccaagc atatcaccaa aatagctatc cccaattgcc gctaccttgc
      181 attcaaagat aaatatgctt atgtgagcgc ttatgcaggc cccgtacaga tagcaccgga
      241 tgcccggatc ggatatgtgg ccaaaatcga tacggtaagc cttcaggtcg tcgatgagtg
      301 cattgtaggt tatcagcccg aagagatggc cattgtgggc aataaactct atgtcgccaa
      361 ttccggcggt taccgtgtcc cgaattacga ccgtaccgtg tcggttatcg acctgaaaac
      421 ttttacggaa gagaaaaaaa tagatgtcgc tatcaacctt caccggatac agccggacaa
      481 ttacggcaac ctgtatgttt cttcccgcgg agactattat gaaatacctt ccaaaacatt
      541 cataatcgac acctcaactg acgaggttgc atacgagttc gaggacctgc ccaatacaca
      601 catgaccttg tgtcgggatt cgctgttcct ttacagtacc gaatggagtt atctgacaaa
      661 cgattggacg gtatcctatg ccatcgtaaa cacgcgcaca cgggagatcg ttacgcgcaa
      721 ctttatcaaa gacggcaccg aaaagcgtat ccagacacct tatggaatcg ccgtcaaccc
      781 aaacaccgga gagtttctgg ttaccgatgc caaagactac gtccgtgccg gaaccctgca
      841 ctgctttggg ccggacggca tacgaaaatg gtcgataagc accgggaaca taccggcaca
      901 tattgttttc acacataaaa aattgcaacc gctggaagag taacttaaca cacttgaata
      961 tgaaaaaaaa ttatgagcga atcgttttac tgcttctatc ggcgttgctt tcggttggat
     1021 ttcttgccgg gtgcaacgac gctgataacg gagacgacgg ttatctcctg aaaaaggaag
     1081 acatctctgt gaaccggccc gacgggggat ttaaggctct ggtcaaccag cctttccgga
     1141 tcgaagtgaa aagcgtttcg gatgagggcg tttcctatga atggtctctc ggtgattcga
     1201 aaatagccga ttcgaagaat ctggaataca ccttcacttc gttgggaaca ttcaccctta
     1261 cgctgcatgc cagccaggga acgaccacct tcgactatga tttcgaggtc aaagtaacca
     1321 ccgattacgt actcaaaaag gaagatataa ccatcgaaga gcccgaagga ggatttagag
     1381 ccaaggtcga ccaactgttt cggatagaag taaccagcgt gtccgacgac ggtgtctctt
     1441 acttatggtt cgaggatgag gagccggtcg ctcaaaccaa gaatcttgag cacatgtttt
     1501 cacatggcgg cgctatcggc ttgaaattaa cagcatcgca aggggatatc ttctttgatt
     1561 attatttcac tgtttttgtc gaatatgctc ctatcgaccc gcctgcggaa ggggcgaatc
     1621 cctatatcac caaagtcttc gactacatgc cggcagtcgg acaatttacc aatacgctgc
     1681 cgctgtacga ggagggggat acgcaggaga caatgaatca caaagtattg gacgccatcg
     1741 gcaataataa acgcggaatg atcaccctcg gcggattcgg cggctacgta acggtcggtt
     1801 tcgaccatac aatccagaat gtcgaaggct tgcgagactt ccgggtttta ggcaatgcct
     1861 tttatgcaaa tgccaatccc aatccggatg ctccagaggg cggaagctgt gagcccggag
     1921 taattatggt ggcctatgat cccgacaatc tcggaccgga caacgtacaa tggtatgaaa
     1981 tacagggcag cgcccatgtg gatcctacca aggaaccgtg gtatgaaatg gcgaaggtca
     2041 atggtaacga tgtaaacatt tacttcgatt accggataac ctattaccgt cccgacagcg
     2101 aaccaacatc gagagacgaa tgggatacgt atataaaatg ggaggataat cagggaaatt
     2161 ccggctacaa aatgaaaaat cagtatcatt cacaaccgta ttatccgctt tgggccggaa
     2221 atacgctgtc gtttacaggc acatgcctgc ctcagaatgc cattgacgaa agcggttcgg
     2281 gaacctattt cgttctttac aaattccgct atggctatgc ggacaatgaa atcaacagct
     2341 atgacgactc gtcgatcgat ataagctggg ctgtcgatgc gagcggaaac agcgtcaacc
     2401 tgccgggagt cgattatata aaaatataca ccggtgtcaa ccaagagaac ggttggcttg
     2461 gggaatgttc gaccgaaata atgggtgtgg aagacctgca tttgctcaaa gaggaaatac
     2521 acacaaggcg ataaagaccg aaataacagg caattcaagt tttctgaact tcgaaaactc
     2581 atttcgattt acaaatagtt aatcggcggc gggccttttg atcgcggtga accattgcaa
     2641 acattcctgc atttaaatcc cgccgccgtt ctttcacatc tgtctgcgag aaccggaaaa
     2701 atagagatta gtagcacgtt gtctgccata acaacgcaat actccggttt ccacagacag
     2761 atttttgctg atttgcattt cgaaaacaat agaaaatttt tacagcaagc acaaaaattg
     2821 aaaaaatggt cttatcaaat atgctttgtt ttaattcaac caacggatta cacaaaacaa
     2881 aagtaatatc aacatttggt tttcgcattc aaccatttct tctctgcggg gaaaatgcgg
     2941 ggaaaacccg aaaattaaaa atcgcttaac ctgccataat caacaaatta agcgatttta
     3001 ctggtacccg gagccggggt cgaaccggca cgacattgct gtcattggtg tttgagacca
     3061 acgcgtctac cgattccgcc atccgggcat ttccgcgagc gttacacggc gaatcgggtg
     3121 gacaaagata ggtgattttc gtaacttttc aaaaaatacg gctatttttc gaaaaaggcc
     3181 ctgatttttt tcgcctttgc cgccccgacc agcgccgaaa gttcttcgat gttggccgca
     3241 cggacctttt ccaccgtgcg aaaatggcgc agcagggtct ggaccgtctt gtccccgacc
     3301 ccctcgatct gctccagttc gctgtggata aacgtcttgc tgcgtttctg ccggtggaag
     3361 gaaacggcga aacggtgcac ctcctcctga atgtgcgcca aaaagtggaa caggggcgaa
     3421 gtgggacgga tgccgaccag cacgggcgga aagccgcaga gcagttcggc ggtgcggtgc
     3481 cggtcgtcct tggccagtcc ggcaatgggg atgtccagcc cgagccgctc cagcacctcg
     3541 tgaatgactc ccatctgccc ctttccgccg tcagcgataa tgaggtcggg cattttggcc
     3601 ccttcggcca tcagccgcgt ataacgccgg aagacgacct cccgcatcga ggcgtagtcg
     3661 tcggcccccg tcacggtctt gatgttgaaa tggcggtact ccttgcggga gggttttcca
     3721 tcccggaaca ccacgcacga agccaccgga tgagcgccct gcaggttgga gttgtcgaag
     3781 cattcgatgt gccgcggctg tctgtcgagg cgcagctcct tttgaacggc attcatcagc
     3841 cgctcggtat accgctcggg attcttgatt tcgaggtttt tcaactgctc ggcgcggtag
     3901 atgcgggcgc tcttccgcga gaattccagc agttcgagtt tctccccgcg cttcgggacc
     3961 gtgaaagtca cgccttcgaa cagcagcgtc gtcgagggca gcagcggcac gatcacctcg
     4021 cgggagagtt cgcctccggc gatgttttcg acgatgtgct ggatggccag cgtcagcatg
     4081 tcgcgctcgt cgcccccgac gcccgtcgag agtttcacgg tctgcacgcc cacgaccgaa
     4141 ccgtggcgga tgcgcacgaa gttgcaccag gccacgtcgt cgtcgggcag cagcgagaaa
     4201 acgtcgacgt cgacgatctt cgcgctgacg atcaccgacc gtccggcata gttgtccagg
     4261 gcgtcgagcc gctgtttgta ccgctgcgcc agctcgaatt tcagctcccc ggccgcacgc
     4321 gccatctccc cttcgaggta ttggcgcacg ggacgcaggt cgcctttcag caccgaaacg
     4381 accatgccga ccagctgcgc atactcctcc tcggactgcc gcccgacgca cggggccttg
     4441 cagttgccca ggtggtattg caggcagacc gtatatttat ctttggcgat caactccggg
     4501 gcgaggttga gtttgcaggt ccgcaggggg atcacctcgc ggatgaagtc gagcacgctg
     4561 cgctgcatca tcaccgatcc gtaagggccg aaatactgcg acccgtcgcg cgtcaggatg
     4621 cgcgtcgact gcacgcgggg aaagcgctcg cgccgcacga cgatccacgg ataggtcttg
     4681 tcgtccttga gcaggatgtt gtaacgcggc tgaaggctct tgatcagcga gttttccagc
     4741 agcagggcgt cggtctcgct ccccacgacg atatggcgga tctcgacgat ctgcttcacc
     4801 agcacacgca ccttcgcgct gtgctccttc gactgcacga agtacgaaga cacccgcttg
     4861 cgcaggctct tggccttacc cacatagatg atcgtccccg agcggtccac gaactggtag
     4921 acgcccggcg acagcggcag cagggccacc tgctccttga gatccggttt ttccgtttca
     4981 gccatacgcc ctgcaaattt agcaaatata ttgcaaatcg gaaagtctat aaaaaggtcg
     5041 cattttttgt ttaattcgtc cgaaaatcat atctttgcac atcgctattt cactacacgc
     5101 caagcctatg agaaaactta tcctcctgct cctgtccggc atgctctcca ccgcatgcgt
     5161 ggacaaagat tacgacctgg gaaacatcga caccgacaac atcgccatcg gcgacgaagg
     5221 gtcgcagttc cgcatcccgc tggtcaaggt gctcgtctcg aaggacgaga tcaaaaacaa
     5281 cggcggcaac atcgaagaga tcttccgcga agccgacatc tggtttccct cccagctgcc
     5341 cgacggcaaa ttcgtcgacc tcgtcaaatt gcaggacaaa gacgatcaga cgtacgtaaa
     5401 cacgctgctc cgaacgctgc gcgaggagat gcggaccagc gacgccaaac tcgcatcggt
     5461 cgtcgatctg gtttgggaca aatacgccgc ggaatttctg ttgcttctca acctgacggc
     5521 tcccgacgag caaaccttca agacagcatt caaaaccgcc taccgcaacg acgcatcgct
     5581 gcgcgaacgg ctcgcggacg aagtcagcgc attggcccgc acctacctga ccggctcgct
     5641 cggaatagac cagctcgaat acgaagtcgg ccatatcgac atcagcagcg acatagtgga
     5701 catgctcgcc gacaacctcg atcccgaggg cacgcccaac gccaggaaca cgctgttcct
     5761 ctacggccag atcaccagcg gactgcccct ttcactgctc ctcgatccga gtttttcgcc
     5821 cacggagatc acgttccagg tcggagtcgg cgcagacaag gcatcgaacg acattcccca
     5881 aacgcagctt ttcgccgaag acctgcggca gatcgtcgag ggcatcacga tccggattcc
     5941 cgtgacgctc acggaatact atcccggcaa aggattcagc gacgaccagt accagatcgt
     6001 catcagcctg agcctgctca agaacggagg actgaaactc gacatctaaa ccgcactcca
     6061 tcatgaaaaa aatatacacc ctcatcgcgg cggcgcttct ggcgaccggc gccgcagccc
     6121 agaaccccac ggcctatttc atggagggtt cgaccttccg cagccagttc aacccggctt
     6181 tcgcgccgct gcgcggctac gtcaacatcc cggccatcgg cggcgtgaac atcaacgtgg
     6241 gcggcaacat cgccgtggac aacatcctct tctcccgcga cggcaagctg gtgacgctgc
     6301 tcgacagctc cgtgtcggcc gccgacgcac tctcgggcct caagcagaac aacctgctgg
     6361 gcatggactt ccgcatgaac gtcatcggat tcggcgcctt taccaaaaac cacaagaatt
     6421 tctggtcgtt cgacctcaac gtgcgggtca acgaagacgc caacctgccc tactcgctct
     6481 tcgaattcat caaactcggc aaggagggcc agatccgtaa cttcggcacc tcgacggact
     6541 cctacctcga ggcggctttc agctactcgt tcccgctgat ggacgaccgc ctctacatcg
     6601 gcatccgcgg taagttcctc gccggactcg cccgtgcgca ggtcacctac gaccgcttcg
     6661 acatctcgct ccgcgaagac cgctgggccg ttctcaccca gggcacgctg gacctcacgg
     6721 ccgccggggc caaagtcgaa acggaccccg acagcgagac cttcgagata ggcgatctcg
     6781 acttcaaacc caccaaaccc gcaggatacg gctttgccct cgacctgggc gccacgtacg
     6841 acatcctgcc caacctgcaa gcgtcgctgg ccgtgaccga cctgggattc atcagctgga
     6901 gcaagaaaaa ctccgtcatg ggcgtctcga cgcaggagac ggaattcacg ggcgccacgg
     6961 ttccggaaaa cgcctcggag ccggttccgg atttcgacct cgaaatgctg aaattcaacc
     7021 aggtcgacgg gcgcagcacg accaagatgc tccacgcgtc ggtcaacgcc ggactcgaat
     7081 acgaagtgtg gcgccacaaa atcggcatcg gcctgctcta cacggcccgc gtctggaaat
     7141 acaagaccat gcacaacatc accggatcgg tcaatttcca ccccgtgcgc tggttcacgg
     7201 tgtcgggaag ctattcggtg gtcgacaacc gcggcggagc cgtcggcctg gcgctgaacc
     7261 tctgccccaa ctggatcaat ttctatctgg caaccgacgt gctgacttcg aagcacacgc
     7321 cgcagtgggt tcccatcaag cagagttcga tgaacgtaac gctcggcctg ggcatcccca
     7381 tcggcaagcg gagccaccgt atcgcggcct acgtccgcga aggcgacaga cgctgacccc
     7441 accccgcaaa caagcaaatt cccggctcga tgagccggga atttgctttg cgaatgcgtc
     7501 ccgcaggccg gaccgggcac ccggacaggc ggccgcagcg cgaaaaaaaa cggatttgcc
     7561 acgcgaaaaa ggcccgcccc ttcggaattt tggacgcacc catatcactt tcgggcaaag
     7621 cgattgcaaa tccggaaact ttctctatct ttgccccgta aggaatccgg aaatgttttc
     7681 cgccatctcc ttcatcctcg aatacattgc gacggcccta aaatctgtgt gaagttgcgt
     7741 cactactttt gaattcttca aaaacgggcc gtcgcaatct tttcttcgct ttcagcaaaa
     7801 accataccgt tttcaccgtc ggtttccagc cgctccagcg ccgcgcgcgt cgccgcacgc
     7861 cccgcctcga gaatctcctc cgaacggtag aactcgaaca tgccgtagct gtcggcgggc
     7921 agcccgacca tgatgtcggg tttgtacaga cggcacatca gctgcgtgat gcgctgctgc
     7981 atgatctgcg acgaagcgat cagcaccttg taataattca gcgacgcatt ggcccggcgg
     8041 acggaatcgg ccccgaaccg ggcgctgacg tccacggcga ccagcaggtc gccctcctcg
     8101 cgccgcacgc ggttcagcgg cagcgggttg accgtgccgc cgtcgaccag cacccggccg
     8161 tcgcggtgca cgggcctgaa aaccgaagga atcgagatcg aagccctgat ggcgtcgtac
     8221 aatcccccgc tgtcgagcac cacttcgtcg cccgtcagca ggtcggccgc cacggcggcg
     8281 aaaggcacgg gcatccgctc gatctgcacg tcggggacca actccttcat cgcctccatc
     8341 acccggtctc ccttgaccag cccttcggtg ctcaacgcga aatcgaccag gctgaaaacc
     8401 ttgtatttat cgagtgcgcg catccactcc ttgaacggtt cgaggtaccc cgaggcatac
     8461 acgcccccga ccagcgcacc catcgaggtc cccgccacgg cgctgatctc gaatccctgc
     8521 ctctccaact cttcgatggc cccgatatgg gccacgcccc gtgcgccgcc gcctgccagc
     8581 accagcgcca ctcttctctt tttcatatat tccctccatt aatgcggacc cggaccttgt
     8641 tccacgcatg ggtcccgaaa agacaacttg cacgcatcgt gccgcacatc tcgcgcaaac
     8701 gcgacatcgg cgcgacgaac cccagctccg aggcgtcgac ccacggacgc accgaagggt
     8761 cgaacaacgc caggaagacg ctgcgtccgc cccggcggtt ctcccgcacg gcctgcgtca
     8821 cgacggcgct gcatcccgac ccgaagggcg cgcacacggc atcgtcggca ttgttgtcgt
     8881 aaacggccca cgacaccagt cccgacaata tgtcgggcgt ggcgaaaaac agcgccccgt
     8941 cggccgtacc gaaagcctcc gcggcctgcg gcgtatcaat gcgcgcaaaa ttgagccacg
     9001 caccggaggc ctccggcacg ccgagccgcc cgatgaactc cagcaccatt tcgggcgtct
     9061 gcttgtagtg ctccttctgc gacacgaagg ccggcacgaa gggcggcatc ggtgcaaagc
     9121 cggtgtagaa cttcccgccc ccgcagccga tattggcggc attgaggctc accgccgacc
     9181 cctcgcgggc ttcggccagc gccttgaaaa aacatccttc gactttgggc acggcacgca
     9241 ccggcccgtc cgaataccag aacagcaacg gcagtcccgc ggcgggtccg aacgcctcgc
     9301 cataggcgga ggcaaactct ttcgcatcca tcattcaatc cgttattatg taatccatcg
     9361 ccacgtcgtg cggctccgca ggcagctccc cgaccagttg gtgggcaaag cacacgccga
     9421 ctttcacggc gtgcacgtcc ggccgggaga ggtatttgtc gtagtaaccc cggccgcggc
     9481 cgcaacgggc gcccgcggcg gtgaacgccg tgccgggaac gatcacgagg tcgatctccg
     9541 acgggtcgca cgtctgcgcc tcgggtcccg gctcggcgat gccgaaagcc cccggacgca
     9601 gcgtctgcgg gtcgtattcg cagaatcgca tcacatcccc ttcgacgcgc ggaaccacga
     9661 tgcgtttcac ggcgctccac cgcgccagcg tctccgccgt gtccggctcg tcgggaagcg
     9721 agcagaaaac acccaccgtc cgggccgcgc cgaaagcctc cagccgcccg gcccggccga
     9781 atatccggcg cgaggcttcg gcgcgctccg cagcgtccat tccgaggttc cgccggcgca
     9841 tcgcggcgcg cagttctttt ttggtcataa aaccctcctt tcaggcataa aattcccgtc
     9901 cgtttctatt gttattccgc aaacaatggc tatctttgcg tgcgtaaaat aaaagcaccg
     9961 gaacacaaat cattaacaaa tataacaaat taaaatcatt atgagctgtt ttctatctaa
    10021 ttcctcgctt ggcaagaagt tagtaatgag cgtgacgggc atgttcctcg tgctcttcat
    10081 cctcttccac atgtcgatga acatcacggc gatcatctcg cccgaagcgt acaacatgat
    10141 ttgcgaactg ctgggcgcaa actggtacgc gctggcagga acggccgttc tggcgctggg
    10201 cgtcttcgtc cacttcttct acgccgtcat cctcacgctg aacaactaca aggcacgcgg
    10261 ttcgcagcgt tacgccgtga cggtgcagga gccgggcgtg gcatgggctt cgaaaaacat
    10321 gctcgtactg ggcttcatca tcctgggcgg actcctgatc cacctgttca acttctggtc
    10381 gaagatgcag ctcgtggaga ttctgggcgg gcacgagaac tcgctgggac tcgaccccgc
    10441 ggacggagct tcgctgatcg cctacacctt ctcgcagtgg tactacgtgg tgatctacct
    10501 cgtatggttc gccgccctgt ggttccacct cacgcacggc gtatggtcga tgttccagac
    10561 cgtgggctgg gccaacgaca cgtggtatcc ccgcctgaag tgcatcgcca acatcgtggc
    10621 cacgatcata ttcctcggat tcgccgccgt ggtgctcgtc tacttcttct gcccctgcat
    10681 cgcaggcgca tgctaatcac cccctttgta gaataataaa cacacaaacg atatggcttt
    10741 aaaattagat gctaaaattc ctgccggtgc tctggccgaa aagtggagca accataagac
    10801 agctatcaag gtcgtaggcc ccgccaacaa gcgcaagctc gacatcatca tcgtcggtac
    10861 gggtctggga ggcgcctccg cagccgcttc gctcggcgaa ctgggctaca acgtcaaggt
    10921 attctgcatt caggattcgc cccgccgcgc ccactcgatc gcggcccagg gcggtatcaa
    10981 cgcagcgaag aactaccaga acgacaacga ctcggtatac cgcctgttct acgacacgat
    11041 caagggcggc gactaccgcg cccgcgaggc caacgtctac cgtctggccg aggtctcgaa
    11101 cctgatcatc gaccagtgcg tgggccaggg cgtccccttc gcccgcgagt acggcggcct
    11161 gctggccaac cgttcgttcg gcggcgcgca ggtatcgcgt acgttctacg cccgcggcca
    11221 gacgggccag cagcttctgc tgggcgccta cgcggccctc aacaaggaga ttgcggccgg
    11281 ttcggtgaag agctacccgc gccacgagat gctggacatc gtcatcgagg acggcgaggc
    11341 aaagggcatc atcgcccgca acctcgtgac gggcgagatc gagcgccacg gcgcccacgc
    11401 cgtcgtgatc gccacgggcg gctacggcaa cgtcttcttc ctgtcgacca acgccatggc
    11461 gtcgaacggc tcggccgcat tccagtgcta ccgcaagggc gccggcttcg ccaacccctg
    11521 cttcacgcag atccacccca cctgcatccc cgttcacggc gaccagcagt cgaagctgac
    11581 gctgatgtcc gagtcgctgc gtaacgacgg ccgtatctgg gttcccaaga aactcgagga
    11641 cgtgaaggcc atccgcgccg gcaagctcaa accctcgcag atcgccgagg aggaccgcga
    11701 ctactatctg gaacgccgct acccggcctt cggcaacctc gtgccgcgcg acgtggcttc
    11761 gcgcgccgcc aaggagcgtt gcgacgcagg ctacggcgtg aacgagaccg gtctggccgt
    11821 atacctcgac ttcaagaccg ccatcgagcg tctgggcaag gacattatca agcagcgtta
    11881 cggcaacctc ttcgacatgt acgaggagat caccgacgtc agcccctacg agcagccgat
    11941 gcagattttc cccgccgtgc actacacgat gggcggcatc tgggtcgact acaacctgat
    12001 gaccaccatc ccgggtctct acgccatcgg cgaggccaac ttctcggacc acggcgccaa
    12061 ccgcctcggc gcatcggccc tgatgcaggg tcttgccgac ggttacttcg tgctgcccta
    12121 caccatcggc gactacctct cgcacaagat ccaggccccg aaggtgaaga ccgacaccaa
    12181 ggccttcgac gaggccgaga agggcgtcaa ggagaagatc gccaaactcc tcgcaatcaa
    12241 cggcaagcag tcggtggacg acatccacaa gaagctgggc cacatcatgt gggagaacgt
    12301 cggcatggcc cgtacgaaag agtccctcga aaaggccatc accgagattc aggccctgcg
    12361 caaggagttc tggaaggacg tgaaggtcgt aggcaaggag aacgacttca acgtcgaact
    12421 tgaaaaggcg ctgcgtctgg ccgacttcct ggagctgggc gagctgatgg cccgcgacgc
    12481 cctcaaccgc gaggagtcgt gcggcggcca cttccgcacg gaacaccaga ccgaggaggg
    12541 cgaagccaag cgcgacgacg agaacttcgt atacgccgcc gtatgggagt acaagggcat
    12601 ggaccaggct ccggaactca ccaaggagcc gctgaacttc gagttcgtgc accccgcaca
    12661 gcgcaactac aaagattaag gccatttgac gttgaacttt aatatcgaat cgaaaccatg
    12721 aattttacat taaagatatg gcgtcaaaag gacgctaaat ccaaaggcgc tttcgagagc
    12781 tacaaggtgg agaacatttc ggccgacacc tcgttcctcg aaatgctcga catcctgaac
    12841 aacaatctca tccacgaggg caaggagccg gtggccttcg accacgactg ccgcgagggt
    12901 atctgcggca tgtgctcgct gcacatcgac ggacaggccc acggtcccag ccagggcgcc
    12961 acgacctgcc agatctacat gcgcaagttc aaggacggcg cgacgatcac catcgagccg
    13021 tggcgctcgg cagcgttccc cgtcatcaag gacctcgtgg taaaccgttc ggcttacgac
    13081 cagattctgc aggccggagg cttcatctcg gtgcgcacga actcggtgcc cgacgccaac
    13141 gccattccga tctcgcaggc cgacgccgag gagtcgatgg acgccgccgc ctgcatcggc
    13201 tgcggagcct gcgccgcgac gtgcaagaac ggttcggcca tgctcttcgt cgccgcccgc
    13261 gtgtcgtcgc tcgccaaact gccccagggc cgtgtcgagg gtgcgcgccg cgccaaggcg
    13321 atggtcgcca agatggacga actgggattt ggcaactgca ccaacacggg agcctgccag
    13381 gccgagtgcc ccaagcagat ttccattgcg catatcgccc gtctgaaccg cgagttcctc
    13441 tcggcgaaat tcgaggacta acgactgtcg cgagtgcgat aacgaccagg gccggagcgt
    13501 tgctccggcc ctttttatgc cgggcgatat gcgcgtcgcg cattcagaca gacaatccct
    13561 cccggcctcc ctttgaaaag ggaggagagg acacccccgt ctgaaccgca agctcctctc
    13621 cggcgcatac ccccccccga accccaaatt gccgccgttc taaatatagg tatgaaaaat
    13681 attttcaaaa aataaggtac tctgtattgc ataatactaa aattcgtatt atatttgcat
    13741 tgtaataata gtaaaacccg caaaacatca aaccgcgaca atacttttac gaccatgaaa
    13801 gagactgtaa acgtaaacat cggctccgtg gcattcatcc tcgacgagga cgcctaccgg
    13861 gtactgggca gctatttcga cgacatccgg cggcgtctgc cggagggtga cgccgaaacg
    13921 atgggcgaca tcgaggcccg tgtggcggag atattccgcg agcgggtcgc ctcgcccatg
    13981 cgggtcatta cgctcgacgt cgtccgtgcg acgatggccc agatgggcag tccggccgat
    14041 ttcggcgaac cccgcggcgc ggagcggtcc gagtccgccg aggaagggac cggaaccgaa
    14101 tccgccgaac agccgcccct gcgcaaactc taccgctcgc gcaccgagcg ttcgatcgcc
    14161 ggcatctgcg ggggtctcgc cgcgtatttc gactccgacc cgacgctgat ccggctgctg
    14221 atgctcctgc tgatcctttt cggcggactt tcgatctggg cctacatcat cctctggatc
    14281 gtcattcccg aggagccggc ccgaaaattc aatatcaaca gcaaaaaccg ataaaatcat
    14341 ggcaacgaac gaaaacagac ggttattccg ttcccaagac agcattatcg caggcgtctg
    14401 tgccggcctg gccgaattct tcggactcga tacatcactg gtacgcatcg caaccctgct
    14461 cctgatcttc ttcggaggtc tctcgctctg ggtttacatc atcctctggc tgatcgttcc
    14521 caaagccccc aaaaggttaa acgcatagca ccatggctga agacaacgta aaggcgcaaa
    14581 tgcgcaaagg aattctggag tactgcatcc tcgccattct ctcccgcgag gactcgtatg
    14641 ctccgaagat catcgccgaa ctcaagcagg ccgagatgat cgtagtcgag ggtacgctct
    14701 acccgatcct cacccggcag aaaaatgccg gactgctgac ctaccgctgg gaggaatccc
    14761 cgcagggtcc gccccgcaag tactacacgc tcacggacaa aggccgcgaa tacctcgcaa
    14821 cgctcgacga agcctgggat gaactcgtcg gacagatcca actcatccgc cacggaaaaa
    14881 acaattaacc cccaaaaaac aaaaccatga aaaaactcct gctgatagcc gtcctgatcg
    14941 cagcgtgcct ctccgcaacc gcttatgtcg cctgcgtcgc agcccccctg ctgggcaaaa
    15001 acatcaaggg cagcggcaag atcgtcacca aaaccgttcc ggcacccgat ttcgacggca
    15061 tcgaagcctc gcgcgccgtg aaagtcgtca tctcggacaa ggtgtcggac atccgcatcg
    15121 aagccgacga caacctgatc gacctggtgg tggtccgggc cgtcaagggc aaactcgaag
    15181 ccaccctcga tcaaaaggtg aacaacatcc agaacggcaa cgtcacgatc accgtcccgg
    15241 ccaacgggaa aatccgctcg ctcgacgctt cgagcgcctc gaagatcatc ggcgagacga
    15301 cgctcaaagc cggcaaattc agcatagagg cttcgagcgc cgccaagatc aaagccgcgg
    15361 tggaagccgt ctcctgcacc atcgaaacat cgagcgcctc gaaggtcgag gcctcggtcg
    15421 aggccgaaag ctgttcgctc gacgcatcga gcgcatcgaa aatcatcctc gaaggttccg
    15481 ccgggacgtt cagggccgac atgagttcgg catcgaaact caacgccgaa aaattctcgg
    15541 ccgtcaacgc ctcgatcgac acatcgagcg ccgccagcgc ttcgatcgat tgcagcggaa
    15601 aactcaccgc cagcgcatcg agcggctcgt cggtccgcta ctcgggcgac tgccaaactt
    15661 cgctggaaaa gtcgagcggc ggcagcatcc gcaaactctg aattccgaaa cgacgcgaca
    15721 accatgaaag aggttaaaaa atgcagcatc tcgggcgtgg cattcacgat ggacgccgac
    15781 gcttacgagg ccctcgaaac ctacctcgag agcctcaaga caacctataa ggacacggcc
    15841 gacggcgcgg agatcgtcgc cgacatcgaa gcccgcatcg cggaactgat cctctcggcg
    15901 caggataaca cccgcatcgt ggagaaaccg ctgatcctga acatcatccg gcagatgggc
    15961 tcggccgagg acatctcccg ggagagcgtc gaccgcgacc tgcactgcga cacgccgcgc
    16021 atcccccgcc ggctctaccg cgacacggaa aacgccaagc tgggcggcgt ctgcgccgga
    16081 atcggcaaat atttcgacat cgacccagtg tgggtgcgcc tcgggctgtt tctgcccctg
    16141 ctgttcacct gcttcgggtg gattcccttc ctgcactggt tcagcccaat gttcggcaac
    16201 ctgttcggca tcttcctgat ctgctatttc atcatgtggt tcgccgttcc ggcggcccgt
    16261 tcggcgcggc agaaactcga aatgaacggc gagaagatca ccgcacaatc catcggcgag
    16321 gtcaccgcg
//
