LOCUS       gnlProkkaJPCKNAAK_1    23227 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JPCKNAAK_1.
ACCESSION   gnlProkkaJPCKNAAK_1
VERSION     gnlProkkaJPCKNAAK_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:45:37
            Original ID  :: gnl|Prokka|JPCKNAAK_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 822152
            Orig. end    :: 845379
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23227
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13227]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13227
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..23227
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23227
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="2"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             706..1365
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 180.3; E-value: 6.9e-55)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_827"
                     /transl_table=11
                     /translation="MARILVIDDQKDIVQLVVKALELQNHNVTGLTSVLDLDKNSLPRF
                     DLILLDIMMPDVDGLQFCHEIRNQVDCPILFITAKTQEADIVQGLSYGADDYICKPFGV
                     KELQARVAAHLRREHRERHHKLSLGEFQFDLSAQELYIENQLLDLTKSEYGICQFLAEN
                     KGQVFSKEQIYTHLYGYEDKGSPAAVAEHIKNIRAKLKEVGQNPIETVWGIGYKWH"
     CDS             1356..2750
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 125.4; E-value: 5.9e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_828"
                     /transl_table=11
                     /translation="MALIKKREHSLRTILLSYVVSLTVLSVISSLLILYLFSLSFRFGV
                     VIPANQVESDLSAVRSDIETSKVFNPEILPDGTSYVFLTRDFKLKKSNMPVNLQEESLL
                     NYQFKNAHGEKYGYFQSFERSDGIVIVNYQLSPRYRNEWMNQHFPNADLMMIGSMFVSI
                     LIIFIILTFYYANKLSQQLKPILRVTEKISQQDLDFQTSQSTIKEFNQVLSGLDHMRIA
                     LRESLMENWKAEQDKQNQISALTHDLKTPLTVARGNAELLAMTSLDENQTDLLEHFQKG
                     IAQVDAYVKELSELNKMSLKKTLTLEEVPVKEFVEDIYDQTLSLAQTKQINVVFDKKEI
                     AKESIGNWDKSLLNRAIMNIVSNAVEHTPSGSQLLLTARVEEDEFKFICLDSGPGFSLE
                     SLENATQLFYQEDKSRQSRNHSGLGLTIANDIIRLHYGSLSLANDNGTGGAKVTIILPL
                     LNTDDS"
     CDS             2851..4194
                     /locus_tag="ctg1_829"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERALKDLQTFIDA"
     CDS             complement(4459..5250)
                     /locus_tag="ctg1_830"
                     /transl_table=11
                     /translation="MADQKANGIDILTDGKFGRSMWHLDFVWGLKGIERYIAEHGYTFK
                     DHDGGQYETRKDIGIRITEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHAYTELA
                     IFDRLAVPGQVYETNEELKKGLINAYKEFLDEYKAVGGKIVQFDDCLWELFDPSNPTSF
                     YSDGNGDLAELADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRFASEGTYEDIAKKF
                     LAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             5561..5989
                     /locus_tag="ctg1_831"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             5991..6284
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 60.2;
                     E-value: 2.8e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_832"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDASIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             6495..6794
                     /NRPS_PKS="Domain: PKS_KR (3-98). E-value: 4e-08. Score:
                     25.2. Matches aSDomain: nrpspksdomains_ctg1_833_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     90.7; E-value: 1.8e-27)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_833"
                     /transl_table=11
                     /translation="MSKVAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAE
                     LSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPTKSLDTITEE"
     aSDomain        6504..6788
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_833_PKS_KR.1"
                     /evalue="4.00E-08"
                     /label="ctg1_833_PKS_KR.1"
                     /locus_tag="ctg1_833"
                     /protein_end="98"
                     /protein_start="3"
                     /score="25.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAELSE
                     DKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPTKSLDTITE"
     CDS_motif       6510..6578
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_833_0001"
                     /evalue="9.20E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_833"
                     /protein_end="28"
                     /protein_start="5"
                     /score="11.9"
                     /tool="antismash"
                     /translation="IVTGAGQGIGFAISKRLVEDGVK"
     CDS             7112..7258
                     /locus_tag="ctg1_834"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             7646..9478
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 549.8; E-value:
                     1.4e-166)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_835"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDTIEEPYIKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             10001..10858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_836"
                     /sec_met_domain="TIGR01716 (E-value: 6e-45, bitscore:
                     150.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDALYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCITAMKLANSENLAIKFENHLSG
                     VLKM"
     CDS             10918..11718
                     /locus_tag="ctg1_837"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKTISKHFQLNFIDKE"
     CDS             11778..11927
                     /locus_tag="ctg1_838"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEVVSSGLSIDIMEIKPSVATELIDGLKGRC
                     PPSV"
     CDS             12010..13227
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_839"
                     /sec_met_domain="Streptide_RRE (E-value: 5.7e-15, bitscore:
                     52.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.5e-20, bitscore: 70.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.1e-09, bitscore: 32.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.7e-10, bitscore:
                     37.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7.1e-08, bitscore: 29.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNVYSIFFNWYNKQGILRNNRNNKLFSLNLATFLALKFMYQFS
                     LKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKIPLKVIQIEVTNKCNLRCMH
                     CYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLLQGLSEIIEEVLKEGMCTTI
                     FTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRGRGTFKRTIKNIEYFRSLGV
                     PVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFERNNRLSISDEEFNNAILCIP
                     NIQANCNNISESTFESFYCGAGNSYVFINSSGDVGFCPTLSSTKFCGGNINEKTLNDIW
                     INSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGSIGSPDIQECKLAYNLTGIK
                     PKSMSL"
     CDS             13224..13967
                     /locus_tag="ctg1_840"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREGAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             13974..15146
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 61.4; E-value: 1.2e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_841"
                     /transl_table=11
                     /translation="MKIKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             15400..17076
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 503.4;
                     E-value: 1.4e-152)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_842"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.4e-50, bitscore:
                     168.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.1e-45, bitscore:
                     149.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLVTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQEEMKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAA
                     FASLLQEALTQAVDGPVLIDVPIDYKDNIKLGETILPDEFY"
     CDS             17092..17811
                     /locus_tag="ctg1_843"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRYEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSNADIKFADVATRQPEYEVDDISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             17899..18015
                     /locus_tag="ctg1_844"
                     /transl_table=11
                     /translation="MNVQSDEDTLLKVDEVSKTEAQAFDVFDQPISRFKFRV"
     CDS             complement(18231..19121)
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 306.9; E-value: 3.4e-93)"
                     /gene_kind="other"
                     /locus_tag="ctg1_845"
                     /transl_table=11
                     /translation="MRLIKNNTELIGIKDQNIKISLVFETDTHIEIQAKLDYPAPSCPH
                     CHGKMIKYDFQKPSKIPLLEQAGTPTLLRLKKHRFQCKSCRRVTVAETSIVEKNCQISN
                     LVRQKVTQLLTEKVSLTDIARRLRVSTSTVYRKLDQFTFKKHYDKLPAVMSWDEFGFKK
                     GELAFVAQNYETNQLITILDNRRQTTIRNYFLKYPLKVRQQVQFITMDMSGAYIPLARK
                     LFPNAKIVLDRFHIIHHLGRAFLKTRIAIMNQFDKKSLPYRALKNHWRLFQKDSRKLIS
                     QLFLFKDFPPNFSTT"
     CDS             complement(19378..20082)
                     /locus_tag="ctg1_846"
                     /transl_table=11
                     /translation="MTEKGIIISEKLADLAGISVGDEVTVQNSQDKDIKLKVAGISEMY
                     MGYFIFMNESTYKDAFGKEASQNATILTLKDHSDKNVEQTASRFMSLDGVKGDVQNTTL
                     KAQIKTIVNSLSRVMGVLISVSILLAFVVLFNLTNINVAERIRELSTIKVLGFFNKEVT
                     LYIYRETICLSIIGILVEFGLGLGLHQYMVDVIPPENIMFNPNLGWLIYAVPTLVIIII
                     LTGSGYLCEPTP"
     CDS             20334..21056
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     76.2; E-value: 4.8e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_847"
                     /transl_table=11
                     /translation="MRGRVSSYLADFSKLDNVYRFVEEIKRDFQRIDILFNNAGLYAGK
                     ERKASGENVELTFMLSVLVPYIFITELIPLLEKLPDGLVINTSSYMHHFAKVKDLDFGF
                     EKEYNPGLAYNNSKLYTIWMTRYLARDFFLKGSNTTINAYHLGLILTNLGNNSSDKKTE
                     KSLFGRLMKSLSKDLDQGIETGYYLTLSEEVSGLTGYYFDEKKVKSVSEKGYSFEKTQK
                     LMNYCQEKVKMFKEKQNV"
     CDS             complement(21233..21445)
                     /locus_tag="ctg1_848"
                     /transl_table=11
                     /translation="MLLLILLGIFTAFLSLAFALLHLMASLSELRKHKNTLGNRLLLIG
                     SNLATFSHPLLPFADCCFIPLADRS"
     CDS             complement(21484..22023)
                     /locus_tag="ctg1_849"
                     /transl_table=11
                     /translation="MTAQDRRITKTRKAIYQAFLYLLNQKDYEAITVQEIIDLADVGRS
                     TFYSHYESKELLLDELCQKLFHHLFERTQYLSPQDYLAHIFQHFKKNQDHVTSLLLSKN
                     DYFIRQLRKELEHDVYPMVADELIQSHPNIPHSYLKHLVITNFIETLTWWLKKGKSYSE
                     QEVVQFYLEILNVASN"
     CDS             22157..23053
                     /locus_tag="ctg1_850"
                     /transl_table=11
                     /translation="MSSKYAVWLAFFLNLSFSIVEFIAGGIFVSSAVLADSVHDLGDAL
                     AIGLSAFLETISNREEDSRYTLGYKRFSLLGALVTAVILMTGSGMVILENISKLFHPQP
                     VNDEGLLWLGIIAISVNLLASLVIRKGQTKNESILSLHFLEDTLGWLAVILMAIVLRFT
                     DWYILDPLLSLAISFFILSKAIPRFWSTLKIFLDAVPEGVDIKQVKNDLEQLDNVASIN
                     QLNLWTMDGLEKNAIVHVCLEHVKHIEVCKESIRDLLKESGFQNVTIEVDEDLATHQAH
                     KRNIEELEAESEQQHHH"
ORIGIN
        1 tgtgattgag ggttttattc atacccataa ccggaagaaa tacttcctaa agatttattc
       61 tttagcaatt gtgatgggac tgattcaatt tggattctat aattttctac atcctctagt
      121 tagaccagat ggtttctttc cacaaaatat gatgctgtcg tcattcgcaa ttttgctcgt
      181 tgctcttcaa gggattgcat ggattcaaga aaagaaatac cttaaaggga taccaacttt
      241 actttttcca ttgttgcttc catggttaat gatgcctttt tatatgctaa gtgtgaacaa
      301 acctatgttt ggttttctac taaatttact caatttcaca gtattgccag tccatacatt
      361 tatcagtgat ggaggaacgt ggttgctttt gaccggtatc gctatgtatc tttgtcatag
      421 gaatcttatg aaagaagtgt ttgcttttat gagtgttagt ctcgtttggc tgctaatggc
      481 gattgtttta agtagacctt ctttttacga tttaatattc aaatactttg aatggatgga
      541 aatattttca gcacctttaa tgctttctta taatggtcaa agagggaaag ggtcaaaata
      601 tttgttctat gttttttacc caacccatat ttatctactt tacgccttgt cagttatctt
      661 ctatagatga tatgataagg ataactttga aggaaaggag aggctatggc tcgaatactt
      721 gttattgatg atcaaaaaga tattgttcaa ttggttgtaa aggctttaga gctccaaaac
      781 cataatgtga cagggcttac aagtgtttta gatttggata agaactcttt acctcgattt
      841 gacctgattt tactggatat tatgatgcct gatgttgatg gtctacagtt ttgccatgag
      901 attcgaaatc aggtggattg cccaatcctc tttattacag ctaaaacgca agaagcagac
      961 attgtccaag ggttgagtta tggtgcggat gattacattt gcaaaccatt tggggttaaa
     1021 gaactccaag cgcgtgttgc agctcacttg agacgtgaac atcgtgagcg tcaccataag
     1081 ctttcacttg gggagtttca gtttgacttg tctgctcaag agctttatat tgagaatcag
     1141 ttgttagatt tgacaaagtc ggaatatggt atttgccagt ttttagctga aaataagggc
     1201 caagtctttt caaaagaaca aatctacacg catttgtacg gctatgagga taaaggcagt
     1261 ccggcagcag tggctgaaca tatcaagaat atccgtgcaa agcttaaaga agttgggcaa
     1321 aatcctattg aaacagtttg ggggattggt tacaagtggc actaataaaa aaacgagaac
     1381 actctctaag aacaatcttg ttatcttatg tcgtcagtct tacagttctc tctgtaatca
     1441 gcagtcttct tattttgtat ttgttcagct tgtcttttcg ttttggagtt gtgattccag
     1501 caaatcaagt tgagagtgat ttgtctgctg tgagaagtga tattgaaact tctaaggtct
     1561 ttaatcccga gattttacct gatggcacga gttatgtctt tttaactagg gattttaagc
     1621 ttaaaaagtc taacatgcct gttaacttgc aagaagaatc cttactaaat taccaattca
     1681 agaatgctca cggtgagaaa tacggatatt ttcagtcttt tgaacggtca gatggcatag
     1741 tcattgtcaa ttatcaacta tcacctcggt accgtaatga gtggatgaac cagcattttc
     1801 ccaatgctga tcttatgatg attggttcaa tgtttgtatc tatcttaatc atatttatta
     1861 ttttaacttt ttattatgca aataaattga gtcagcaact taaacctata ttaagggtta
     1921 ctgaaaaaat ttcccaacaa gatttggatt ttcaaacttc tcagtctaca attaaggaat
     1981 ttaatcaggt tttaagtggt ttggatcata tgcgtatagc acttcgtgag tctttgatgg
     2041 aaaattggaa ggcagagcaa gataaacaaa atcagatttc tgccctaaca catgacttaa
     2101 agacgcccct aacagttgct cgtggaaatg cggaactctt agctatgacg tccttggatg
     2161 aaaatcaaac ggacttgtta gagcattttc aaaaaggtat tgcacaggtt gatgcttatg
     2221 taaaagagtt gtcagaactc aacaaaatga gtttgaagaa gaccctgacg cttgaagaag
     2281 ttccagttaa ggaatttgtt gaagacattt acgatcaaac cttgtcatta gctcaaacga
     2341 aacaaatcaa tgtggtattt gacaagaagg aaattgcgaa agaaagcata ggcaattggg
     2401 ataagtcctt gttgaatcga gctattatga atattgtttc aaatgccgta gagcatacac
     2461 ccagtggcag tcagttgctc ctgaccgcta gggtagaaga agatgaattc aagtttatat
     2521 gccttgattc tggtcctgga ttttcccttg aatctcttga aaacgctact cagctatttt
     2581 atcaagagga taaaagcaga cagagtcgca atcatagtgg ccttggtctg actattgcta
     2641 atgatattat tcgtttacac tatggtagtc tttctcttgc aaatgacaat ggcacgggtg
     2701 gtgctaaagt gactatcatt ttaccccttt taaatacaga tgactcctag tcgccagatg
     2761 aggagttttt tgctatacta ctaagagtaa aaatgaagaa agatttgtgg gagcaggatt
     2821 tcatcttgtt tccgaagagg tattagtgtc atgtctcaat caaaagcaga ttatattaac
     2881 gtgattggag ctggtttggc cggatccgag gcggcttatc agattgccaa acgtggtatt
     2941 ccagtaaaac tttatgaaat gcgtggggtc aaagcaacac cacagcataa gacaacaaat
     3001 tttgcagaat tggtttgctc taactctttc cgtggagata gcttgaccaa tgctgtaggg
     3061 cttctaaaag aagaaatgcg tcgtttggac tctatcatta tgcgtaatgg agaagctcac
     3121 cgtgtgccag caggtggtgc catggcggtg gaccgtgagg gctatgcaga agcagtgaca
     3181 gctgaaattg aaagtcatcc cttaattgaa gttatccgta aagaaatcac agaaattcct
     3241 gatgatgcta ttacagttat tgcttcaggt cccctaactt ctgatgcttt agctgaaaag
     3301 attcatgagc ttaacggtgg agacgggttc tatttctatg atgccgctgc accaatcgtt
     3361 gataaagcaa ctatcgacat gaacaaggtt taccttaagt cacgctatga taagggtgaa
     3421 gcagcttatc taaactgtcc aatgaccaag gaagagttca tggccttcta tgaggccttg
     3481 actacagctg aagaagctcc tttgaattct tttgaaaaag aaaagtattt cgaagggtgt
     3541 atgcctatcg aggttatggc taaacgtggt attaaaacaa tgctctacgg tcctatgaaa
     3601 ccagttggtt tggagtatcc tgaagattat atgggtccac gtgatggtga cttcaagaca
     3661 ccttatgcgg ttgttcagct tcgtcaggac aatgcggctg gtagcctcta caatatcgtt
     3721 ggtttccaaa cccacctcaa atggggagag caaaaacgtg tcttccaaat gattccaggt
     3781 cttgaaaatg cagaatttgt tcgttatggg gtaatgcacc gtaactctta catggattcg
     3841 ccaaacttgc ttaaacagac cttccaatca aaatcaaacc ctaatctgtt ctttgctgga
     3901 caaatgactg gtgttgaagg ttatgttgaa tcagctgcct caggtttggt tgctggaatc
     3961 aatgcagccc gtctctttaa gggtgaagat gaagttattt tccctcatac aacagcaatc
     4021 ggtagccttc catattatgt gacacatgct gaaagcaaac attttcaacc aatgaatgtt
     4081 aactttggta ttatcaaaga attagaaggc ccacgtattc gtgacaagaa agagcgttat
     4141 gaaaaaatcg cagaaagagc tcttaaggat ttgcaaactt ttatagatgc ttgatgctaa
     4201 cataaaaagc cctcacaaga gtgaaggctt ttcgttttag agaggagcga atagaaatat
     4261 cgattagcca aagaatttct tagcgatttc ttgaccttgt ttgattttag cccattgttg
     4321 aggtgttgcc agctcattac ctgagtcaca tgaggcgaaa ccacattggt gaaaggggaa
     4381 gagacgtttt tttggaagga tttgactcgc tttttcaagc aaatcgagaa cacgttcttc
     4441 gtcatctagg tcagtcgttt aagaagacaa tagcccaaat acaacttcag ctttactgtc
     4501 tttaagggct tccagagctt tgatatcacc agctgtatcg ctatcccatt caaggaagaa
     4561 gcggtcatag tgttgctctg ccaagaattt cttagcgatg tcttcgtaag ttccttcaga
     4621 agcaaaacgg atttcataat taccacgaca gttgtgtgtc caaaccgtta aaccaagttc
     4681 gtgagtatag tcaacaacct cattattgat agcaacaaat tcatcggcca attctgccaa
     4741 atcaccattg ccgtctgagt agaaacttgt agggtttgat gggtcaaaaa gttcccagag
     4801 gcagtcgtca aattgaacga ttttaccacc aacagccttg tattcatcca agaattcttt
     4861 ataggcatta atcaaacctt ttttgagttc ttcgtttgtt tcatagactt gtccaggaac
     4921 agccaatcga tcaaagatag caagttcagt gtaggcatga gcaggtcccc agatagtttg
     4981 tttggtatct tcatcaccag cttcagcctt aaccaatttg taaatatcta ggtagtggtg
     5041 gtttttacct gatagaggct cagtgatacg aataccgata tctttacgtg tttcatattg
     5101 accaccatca tggtctttaa aagtataacc atgctcagca atgtagcgtt caataccttt
     5161 gagtccccat acaaagtcca agtgccacat agaacgtcca aacttcccat cggtaaggat
     5221 gtcaattccg ttagcttttt ggtcagccac attcgcttaa tagatgcagt ttcagtttct
     5281 tgataaccag gaagggcatc atagaaagga tactggatgt cgtcacgatg ctcgatttcg
     5341 tccttgtatt tacggagatc cgcaggacga agaagagaac cgactaattg gaatttagat
     5401 tttgtcatta aatttacctc gaaatgtcta tttacatcta tattatttct tatgggaact
     5461 aatgaaaaat agttaatttc ttgctgtgta tatagtttta gactatacaa ggtttagctc
     5521 tgcaaaatga tacttcttat gataaaatgg aaagaaaacg atgaaggttg ggaatatgca
     5581 aaaaacattc tttattatta aaccagatgc tgttaaacgt catctaattg gtcaagtgct
     5641 tgatcgaatt gagcgacgtg gcttcgttat tgagcgtatg gagatgctga tgcttgacga
     5701 agaacgtctt aaagaacatt atgcccaatt ggctgataaa ccttttttcc ctagtatttc
     5761 tgaattcatg atgagtggtc cagcagttat tggtattatg tccggcccag gagttattaa
     5821 gtcatggcgt gatatgatgg gagcaactaa tcctggggat gctgctcctg gaacgattcg
     5881 tggagacttt gcaacagcac cagatggtga catgattcca aatatcgttc atggctctga
     5941 ttcagaagaa tctgcggctc gagaaattaa gatttggttt ggtgagtagg atggatatag
     6001 cacagattca atcagaatta gctcaggatg gactattaat tgatgtcagg actccagaag
     6061 agtacgcaga aggtcatgtt aaggatgctt tattaatacc tcacacgcag tttttcacag
     6121 ctgacattcc agctaaaaaa gacgcctcca tttacctcta ttgtaaaatg ggatctcgtg
     6181 ctgaatttgc tgcaggagta ctgaaagaac gaggatatac taaggttacc accttaggtg
     6241 gcctaggtga tatggaagca ctagggttta agtttgaaaa ataatacaca taaggtcact
     6301 agtggtgatc ttatttgctt tcaaaaagca tgacaaatta ttaacaacgc tttcataaag
     6361 tggtaagatt ctaaatgagt taagaaaaag cctatgaaaa tgactttgcc agaacttgat
     6421 taacttagca tattccaatt gagatagggc ttgtggttaa gcttgtgact acaattggta
     6481 gaggaggatt tcgtatgtca aaagttgcta ttgttacagg tgcaggtcaa ggtattggtt
     6541 ttgcgatttc aaaacgcttg gttgaagatg gtgttaaagt cggggtattg gactatgacg
     6601 ctgaaactgc tgaaaaagca gttgctgagt tgtcagaaga caaggcattt tccgttgtag
     6661 cagatgtgtc taaacaagct gaggtagcag cagctttcca aaaagtagtt gatcactttg
     6721 gcgacttgaa tgttgttgtt aataatgctg gtgtggcacc aacaaaatcc cttgacacta
     6781 ttactgaaga atagtttcaa cgtacattta acattaatat tggtggagtt atctgaggtg
     6841 cacaagctgc ccaagcacaa tttaaatcac ttggtcatgg tggtaaaatt atcaatgcaa
     6901 ctttacaagc aggtgtcgta gggaactcta acttaactgt atatggtgga actaaattcg
     6961 tagttcgtgg tattactcaa actttggcgc gtgacttagc tgattcaggt ataactgtaa
     7021 atgcttatgc accaggtatc gttaagactc caatgatgtt tgacattgcc cacgaagttg
     7081 gtaaaatgct ggtaaagatg atgagtgggg tatgcaaact tttgctaaag atattaccct
     7141 caaacgtttg tcagaacctg aagatgttgc agcagcagtt agcttcctag ctggacctga
     7201 ctcaaactac atcacaggtc aaacaatcat cgttgatggt ggtatgcaat tccattaatg
     7261 ttaaaaggga gagcgaatgg ctctcttttt ttgcttgata aaacataatg tttctgataa
     7321 tatagttata aataattatg tttttaaagg tggattccca tatcagacat cttacactat
     7381 attgctgagc acccattttt tagtcttatt ctattgggaa ttattgtact agcctttggt
     7441 ttagctccat tttcaagtag ttcaatagag aacaagcgtt cagctattat taataagcac
     7501 tacaatgata attttaagaa ataagaagga ctaaatgcag tcataaagca gatattagag
     7561 ataggcaaat gcctgtcttt tttgtataat aggaggtgac ggttcgtttt ttaacaatca
     7621 caagtaagaa ttaggaaaga ataaaatgcc aaatattgaa gaattaaaac aaagacagga
     7681 gaagattcgc aacttctcga ttattgctca tattgaccat ggtaaatcaa cgcttgctga
     7741 ccgtatcttg gaaaagactg agactgtatc aagtcgtgag atgcaggcac aactccttga
     7801 tagtatggat cttgagcgcg aacgtggtat cactatcaaa ctgaatgcca ttgagcttaa
     7861 ctacaaagct aaagacggcg agacttatat tttccacctt atcgacacac cgggacatgt
     7921 ggactttact tatgaggtgt cacgttccct tgccgcctgt gagggtgcta tcttggtggt
     7981 agatgcagct caagggattg aagcacaaac acttgccaat gtttacttgg cacttgataa
     8041 tgacttggaa atcttaccag ttatcaataa aatcgacctt ccagcggcag atcctgagcg
     8101 tgtacgtaca gagattgaag atgttatcgg attagatgcc tcggaagctg tgcttgcatc
     8161 agctaaggct ggcattggta tcgaagagat tctcgaacaa attgttgaga aagttcctgc
     8221 gccccaaggt gatgtggaag cacctctcca agcccttatc tttgactctg tttatgatgc
     8281 gtatcgtggc gtcatactcc aagtgcgtgt ggttaacgga atggttaaaa cgggcgataa
     8341 gattcaaatg atgtctaatg gcaagacctt tgacgttact gaggttggta ttttcactcc
     8401 taaagctgtt ggccgtgact accttgcgac tggagatgtt ggttatgtag cagcttcaat
     8461 taagacagtt gcggatactc gtgtcggtga tacagtgaca cttgcggata atccagccgc
     8521 agaaccactt catggttata agcaaatgaa cccaatggtc tttgctggtc tttatccaat
     8581 tgagtcaaat aaatataacg acttgcgtga ggctcttgaa aagctccaat tgaatgatgc
     8641 cagtcttcaa tttgagcctg aaacgtctca agcccttggt tttggtttcc gttgtggttt
     8701 cttgggcctt cttcacatgg atgttatcca agagcgtttg gaacgtgagt ttaacatcga
     8761 tctcatcatg actgcaccat cagtagttta ccatgttaac actactgacg gtgaaatgct
     8821 tgaagtgtcc aacccatctg aatttccaga tcctacacgt attgatacca ttgaagagcc
     8881 ttatatcaaa gctcaaatta tggttcctca agagtatgtt ggtgctgtta tggagttggc
     8941 gcaacgtaaa cgtggtgatt ttgaaaccat ggaatatatt gatgataatc gtgttaacgt
     9001 tatctatcaa attccacttg ctgaaatcgt ctttgacttc tttgataaat tgaagtcatc
     9061 aactcgtggt tatgcaagtt ttgactatga attgtcagag taccgtcgtt cacaattggt
     9121 gaaaatggat attctcctta atggtgataa ggtcgatgcc cttagcttta ttgtccatag
     9181 agaatttgcc tacgaacgtg gaaaacttat cgttgataaa cttaagaaaa ttattccacg
     9241 tcaacaattt gaagttccta tccaagcggc tattggtcaa aaaattgttg cccgtacaga
     9301 tatcaaagct cttcgtaaaa acgtcttggc taaatgttac ggtggtgacg tttcacgtaa
     9361 acgtaaactc ctcgaaaaac aaaaagccgg taagaaacgt atgaaagcca tcggttcggt
     9421 ggaggtacca caagaagcct tcttgtctgt gctttcaatg gacgaagatg agaaataaga
     9481 atgatagtag aatgtgatgt tctggctatt ttagtaaaaa gttatgataa agaggatttt
     9541 aaaatttacc ttctcaaagt gacgtataga gaatggcacc actaatccaa catataaaac
     9601 attggaagaa attgccgctg caaccaatac tagattagtt gttgactttg ttccaataaa
     9661 gaactagttt ttgtatacac tcaaaaagct ctataatctc tatagtggtt ttacctacta
     9721 cagaaatcat agagtctttt ttatattata cccttattag agaacaacat cataccttaa
     9781 ctacaccaca aaagttagac atcgaaagtc taacttttgt ggtgtcttta ttttctattt
     9841 gtttagccaa cagcaattac aataatgctt tcaaaaatta gaagtaagat agctaaaaaa
     9901 ctttctttat tcatagaaat taacctccta tctcactata tgatataata cttttaagtt
     9961 tatctgggaa attctcgtat atgcaaaaga ggtgcttttt atgaaagatt atggaaaatt
    10021 atttaagaaa tttagagagt ctaggggatt agtcttaaaa gatatcgcaa agttaggcgt
    10081 atcagtatct catatttccc gctttgaacg tgaaaataca gatttgacaa ttagtaagtt
    10141 tatgtcagct ttaaatgcga taaatatgcc tattgatgag tttatgtatg cagcaaacga
    10201 ctttcagaga gatgagttta atgaaatctt agaaaagatt agtttatttg tttcagcaag
    10261 gaacgtgtca ggtatggaaa agttattaat ctctcaagta gaaaaaatcg aaaagcgtga
    10321 gactttttat actctaaata ctattttaat aaaaattcgt ttacaggact tatcagacaa
    10381 aagttactat gatgaatctg atatccaata tttatcagac tacctattct ctgtagaata
    10441 ttggggttgt tacgaactac tgttatttgc gaatactgta gatgtattga atcatcaaac
    10501 aatgatgctt ttatcaagag aaatgtgtaa acgttcagaa ttttacaagg atttaccaaa
    10561 ctaccgaagg ttacactcaa caatgctatt aaattgttat atcataagta ttgaaagaga
    10621 tgagtatatt gatgcgttgt attttgaaaa acagttaaat catagttgtt ttacggaaac
    10681 tgagatttac gagaaattag tgtttcatta ttcaaaaaat ttatatgaat taaagaagaa
    10741 taggagcaat aaagctattc tagaaatgaa gaagtgtatt actgcaatga agctggctaa
    10801 tagtgagaat ttagctataa aatttgaaaa tcatttatct ggagtgttaa aaatgtagtt
    10861 ggatttgtgt atatggtata aattatcagt gtcaaaatta aatgatatat tattgatatg
    10921 agaattatta aatttcctga acagatttca gaagatatca ttcattatac gtttctagat
    10981 gatattatct cttataattg tgaaaagtgt agaggatctt gttgtcatgt gaataattcc
    11041 ttattacttg atgcaaagac agcaagtttt ctaaaacgca cgtatcttaa agattttatt
    11101 gttagtgatg atagtgtttc attgttgagt tgtggtaaaa agtgctggtt tcattctgaa
    11161 ttgggttgta cgataaatga tttaggcttg aacaagccat taacttgtga attatatcct
    11221 tttcatatta agaaaattca gaacttctat attgtttctt ttactccttg tccgacattt
    11281 caactgaacc ttggtgaggg gcagaggtac aaggatatag aggatgtagt tttacgatat
    11341 attaaaactg gggtgccagt ttttagtccg tctttgcatg tttcagagga aaggctgaaa
    11401 tatgagattg agtatcaaaa caattttaaa aacactttat cagagtatta tcgaacaaag
    11461 actgccgatg gcactacaga gtttaaagaa tatgaaaaat ggtatatata ttatttagat
    11521 tttagatggg gaagtatacc cttatcttat acaagttcac aagcaaatca attttggaat
    11581 ctttacaaga gagtttgtga agatgtttat aaaaaaatat catatatacg aacagataac
    11641 atatacttta ttattgcaaa tcagtttaat aagacaattt caaagcattt tcagctaaat
    11701 tttatagata aagaatgatt tctatgattt gttatgggta cttattgatt cttaaataaa
    11761 taatggagga tattacgatg caagttagtg atgctattgc acaaattgaa ttagcagaag
    11821 aagaagttgt ttctagcggt ctatctattg acattatgga aattaaacct tctgttgcta
    11881 cagagttgat tgatggactc aaaggtcgtt gcccaccgtc tgtctaatag aactgattgt
    11941 aggattagag tctatttcta atcctttggt ttttatatta atatttttgg aagattgcag
    12001 ggaattaata tgacgagcaa tgtttactcg atttttttta attggtacaa taagcaagga
    12061 atactcagga ataataggaa taataaacta ttttcattaa atttagctac atttttagct
    12121 ttaaaattta tgtaccaatt ttcattgaaa aagttttctg attcaaagag tcaggtaata
    12181 aaaaatgtta tagattttct aaataacaat gaaatatcac tctctaagac caacactaaa
    12241 attgttgaat tttcaacgaa aataccatta aaagtgatac agattgaggt cacgaacaaa
    12301 tgtaacctaa gatgtatgca ttgttattta cctgattatt caaaggagct cgatagaaag
    12361 aaaatttcaa gtatagtata tgaagctaag cagctaggag taatggatgt tgatttcact
    12421 ggaggcgaac cattattatt acagggatta agtgaaatta tcgaggaagt attaaaagag
    12481 ggaatgtgta caacaatttt tacaaatgct gtatatattc ctgaagattt taaaatattg
    12541 attcaaagat atgatggtat aagactaaaa gttagtttag atggttggaa tgaaacaata
    12601 catgattcaa ttagaggaag aggtacattt aagagaacaa ttaagaatat tgaatatttt
    12661 aggagtttag gagtacctgt tactgttaat gttgttttga ataacaagaa tattagtgga
    12721 gtgaagtatt ttttggagtt gtttgatcga ttagatgtga aatatgcttt tgataggttt
    12781 ttaccttttg aaaggaataa tcgactatca attagtgatg aagaattcaa taatgctatt
    12841 ttgtgtattc ccaatattca agcaaattgt aataatatat ccgaatccac atttgaatca
    12901 ttttattgtg gtgctggcaa ttcttatgtg tttataaatt cgtcaggtga tgttggattt
    12961 tgtccgacat tatcctccac taaattttgt ggaggtaaca ttaatgaaaa gactttaaat
    13021 gatatttgga ttaattcgaa gttcttcaat catattcgaa atgtacgatg taagtattat
    13081 aatgaatgcc ctgcaaatta tgtttgtcaa ggtgggtgta gaagtcgagc tcagtttttc
    13141 ggaggttcta ttgggagtcc cgatatacag gagtgcaagt tagcatataa tttaactggg
    13201 attaagccaa agtcaatgag tttatgaaaa tattatctat tatttatgat ggtggaagta
    13261 gaattccagg agcgagattt gctcccacaa aatattatca agaagcgatg ttatatgata
    13321 ggaaagattc tgatataatt acaattaatt taggtaatca agatttattt tctattgatt
    13381 tagaaagtct aagtcgaact attgctgaat ctaaagttca gattgcttta ggaggagatc
    13441 attcagttac ttatctatta gcaaaggcca ctgttcgaga gggagcatat ttaattgttt
    13501 tagatgctca tttagattac ttcaaagact ttgaaagtgt tgtaaaaaat tggaattttt
    13561 taagtttttt aaccgatatt tttgaaaaaa taattatcat tggggaaagg aattttgagt
    13621 ttcctagttc atttgataat aaaataatca tcctctcaat ggaggagtat tggttaaata
    13681 agagtagagt tttgaaaaag ttagatagtt atattgatga gtcaaaagat atttacttat
    13741 caatagacat tgatgttttg gatccatctg tttttgattc agtatcatat cctattattg
    13801 gaggatttca aatgaacgat tttcttggaa taatttccaa aattttatgt tctgataagg
    13861 tatatttttg tgatatagtt gagtacaatc cgatggttgg aagtgataat gctcacattt
    13921 tttaccaaat gattcaattt gttaaatcaa aattaaggag gatataggaa atattgaaaa
    13981 taaaaaaata tgcagcattg agtatttatt ttaatcgttt ctcatcgtta atctcagagt
    14041 atggttatac tatcttgatc aacattctat tgtctagaat ttctgtgcaa ttagttatgt
    14101 atttttgggt ggtaaagtgt ttagctgcaa tagttacaaa taggattaat atctcaaata
    14161 gtaaactgag cagaaaatac ctgcttattc tgttagaaat tacaaaggca atcttacttt
    14221 tcttactagg ttttggatta aaccatataa ttgtcctatt agttgtattc ataattgagg
    14281 ttgtcaatgt attgttttcc agtttattat atagttgtgt accaattatt atagacaagg
    14341 attcattgat taagtttaac gctaggtata caagcattgg ttcagtatct tattttttag
    14401 caccgttgtt tgttggttta tttattaata aaagtcactt tttattgttt gcagtttatg
    14461 ctcttctttt gatagtggga gctactagtc ttttattttt accaaatatt tcgactttaa
    14521 atttgaaaga agaaagaaaa aaacaaaatt taaacattac attatttaac attctgagat
    14581 ccaaaaaaat tgcattagtt ctattatctg gagttattgt gggatcaatt ggagttgttt
    14641 atgatactta tgaagttgtt tatttaacaa agtatctcgg tattagtgat tctatgtatt
    14701 ccttttcctt atcattttta gcagtttcat tcttagtaat gagcttcctt cttagcttcg
    14761 tgaaacaaat aagttctcat atgaaagctt tcgccttagg tctttcattt tatgttctat
    14821 atctactttt atttagtaca tcttcgaaca tttatacagt actaatgagt tatgtttttc
    14881 tagcgatagg tcagacaatg atggggataa tcgaaaccaa ttattttcag ttgtcactta
    14941 acatgaaaga attacagaaa ctatatattt actcggagac cttacattct gtattttcag
    15001 gcattgctgt tttagtaata ggaagttttg cctttttaag tagtcatctt gttttagttt
    15061 tcagaagtct tgctgttttt gctctgttta ttcttctgtg ttattgtgtg tttgtaaacc
    15121 tcaaaaaact aagcattgat aagtaatatt tataaatcag aaaacaagca aatgagatag
    15181 ttaatctata aagtagacaa acgctatttt gagtgtttgt ctttttttag tcacctagtc
    15241 tgcctttttt cacaagattg tctgaaaact gtgctataat gataacagaa ttgtgaattg
    15301 atgaaagttt gtgaaaaaac gagcagactt tgacactttg tgacttatac ttgaaaggaa
    15361 agttggctct accattttag ggctagaagg actgtgttca tgtcagaaga aaagcaattg
    15421 tatggtgcag atttagtggt tgatagtttg atcaaccatg atgttgagta tgtctttggg
    15481 attccaggcg caaaaatcga tagggttttt gataccttgg aagataaggg acctgaattg
    15541 attgttgccc gtcatgagca aaatgctgct tttatggctc aaggtgttgg acgtattact
    15601 gggaaaccag gtgtagtatt ggtaacatct ggtccaggtg tctccaattt ggctactggt
    15661 ttggtaacag cgacggatga aggagaccct gttcttgcta ttggtggtca ggttaagcgt
    15721 gcagatctct tgaaacgtgc ccaccaatca atgaataacg ttgctatgct tgagccaatt
    15781 accaaatatg ctgctgaagt acatgatgct aacacccttt ctgaaacggt tgctaatgcc
    15841 tatcgtcacg ctaagtcagg gaaaccaggt gcaagcttca tttcaattcc tcaagacgtg
    15901 acggatgctc cggtcagtgt taaggctatt aagcctatga cagatccaaa acttggttca
    15961 gcatctgttt ctgatattaa ctatctcgca caagccatta aaaatgcagt gttgccagtc
    16021 tttcttttgg ggaatggtgc ctcatcagaa gccgtaactt actctattcg ccaaattttg
    16081 aagcatgtta aattgccagt tgttgaaact ttccaaggtg ccggtatcgt gtcacgtgac
    16141 cttgaagaag atactttctt tggtcgtgta ggtcttttcc gtaaccaacc cggagacatg
    16201 ttgcttaaaa aatccgactt agttattgcc attggttatg acccaatcga atatgaagca
    16261 cgtaactgga atgctgaaat ttcagcacgt atcatcgtta ttgatgttga gccggccgag
    16321 gtggacactt acttccaacc ggaacgtgaa ttgattggta atgtagaagc gagcttaaac
    16381 ttgcttttgc ccgctattca aggttataaa ttgcctgaag gttcggttga atatcttaaa
    16441 ggtttgaaaa acaatgttgt tgaggatgtt aagtttgacc gtcagcctga tgaaggtacg
    16501 gtgcatccgc tagatttaat cgaagttttg caagaacaaa cagatgatga tatgactgtt
    16561 acggttgatg ttggtagtca ctatatttgg atggcacgtt atttcaaatc gtatgaacca
    16621 cgtcatttgc ttttctcaaa tgggatgcaa acgctaggtg ttgctcttcc atgggctatc
    16681 tctgcagctt tggttcgtcc taagacaaaa gtgatttctg tttctggtga tggtggtttc
    16741 ctcttctcag cacaagaatt ggaaacagca gttcgtttga aattgccaat tgtccatatt
    16801 atctggaacg atggtcatta caatatggtg gaattccagg aagaaatgaa gtacggtcgt
    16861 tcatctgggg ttgactttgg tcctgtagat tttgtaaaat atgctgagag ctttggagcc
    16921 aaaggttatc gtgcaacaag taaagcagca tttgctagct tgcttcaaga ggctttgact
    16981 caggctgtag atggaccagt ccttattgat gttccaattg actataaaga taacattaaa
    17041 ctcggcgaaa ctattttgcc agatgaattt tactaaaaag agggtgtaga catgtctgaa
    17101 gccataaaat tatttcaata taatactttg ggagccttga tggctgggct ttatggaggt
    17161 actttaaccg ttggagagtt gttagagcat ggagacttgg gtctcggaac attagattct
    17221 atcgatggtg agttgattgt tcttgacggt aaagcctacc aagctaaagg ctctgaaggt
    17281 aaagtcgaag tggtagaagt ttctcctgat gaaaaagttc cctatgcagc agtcgtacct
    17341 caccaagctg aagttatctt ccgtcaacgt tatgaaatga ctgataaaga acttgaggat
    17401 cgtattgaat catactatga tggggtcaat cttttccgtt caatcaaaat caaaggtcat
    17461 tttaaacaca tgcacgtgcg catgattcca aaatcaaatg cggacattaa gtttgctgat
    17521 gttgccactc gccaacctga gtatgaggta gatgatattt caggtacaat cgttggtatc
    17581 tggacacctg aaatgttcca cggtgtgagt gttgctggtt accatctcca ttttatttca
    17641 gatgacttga cattcggtgg tcacgttatg gactttgtta tcgagaatgg tattattgaa
    17701 gttggaccag ttgaccaact cgatcaacgc ttcccagttc aagaccgtca atatctcttt
    17761 gctaaattca atgttgatga aatgcgtaaa gatattacta aggctgaata agcatataaa
    17821 taagatactg tctctttgtc aactatagtg ggtgacgaaa agctaatatc tagagagggc
    17881 cggataggtc ctctttttat gaatgttcag agtgatgaag acacgcttct taaagttgat
    17941 gaagtttcta aaaccgaagc ccaagcgttt gatgtctttg atcaacctat tagtcgcttc
    18001 aagtttcgcg tttgaatagt ccgtttctag tgtgtttttg atgtatttgc ttgtgtctaa
    18061 gaaaagtact aaagacagtt tgaaaataat gattgacctt gctcctattt tcctctatca
    18121 gttcaaagaa ctcatctact ctcttctcct gaaagtgaaa aagcaaaagc tgataaagtg
    18181 tatagtagtc agtaaactct tttgaaaaga ctagtgtctt cgcaacaact tcatgtggtg
    18241 ctaaagtttg gcggaaagtc tttgaataaa aagagttgag agataagttt acggctgtcc
    18301 ttttggaaga gtcgccagtg atttttcagg gctcgatagg gtagtgactt cttatcgaat
    18361 tggttcataa ttgcaattct tgtctttaaa aaggcacgtc caaggtgatg gatgatgtgg
    18421 aaacgatcaa gaacgatttt tgcgtttgga aagagcttgc gagccagtgg aatataagct
    18481 ccagacatat ccatcgtgat aaactgtacc tgttgtcgga ctttcaatgg atacttcaaa
    18541 aagtagtttc gtatagtagt ttggcggcga ttatcaagga tggttatgag ttggtttgtc
    18601 tcataattct gcgccacaaa agccaattcc cctttcttga acccaaactc atcccaggac
    18661 ataacagcag ggagtttgtc ataatgtttc ttgaaagtaa actgatcaag cttacgatag
    18721 acagtggacg tcgacacgcg aagtcttctt gcaatatcag ttagtgacac tttctcagtt
    18781 aggagttgtg taactttttg tcggactaga ttggagattt ggcagttttt ctcaacgata
    18841 gatgtctcag ctaccgtgac tcttctacaa cttttacact ggaaacgatg ttttttcaga
    18901 cgtagtagag ttggcgttcc cgcttgctcg agaagaggga ttttagaagg cttttgaaag
    18961 tcgtacttga tcatctttcc atggcaatga ggacatgatg gtgcagggta atcaagtttt
    19021 gcttgaatct cgatatgagt gtcagtttca aaaacaagtg aaatcttgat attttggtct
    19081 ttgattccga ttaattctgt gttattctta ataagtctca taagttcttc ctaatgatgg
    19141 tttggttgct tttcattata gttcttatgg gactttttgt gtacactcaa aaagctctat
    19201 aatccctaca gtagttttac ccactacaga aattatagag ccaagatact cccctattcg
    19261 acatagggga gtatcttgtt ttaaaacgac gaagtggtcc taactcttcc gttttattta
    19321 ttaagttata gcatatctca ctcaacagat tttagagcct cgagcatatt gactttctta
    19381 aggtgttggt tcacaaagat acccagaacc tgtcagaatg ataatgatta ctagtgttgg
    19441 aacagcgtag atgagccagc caagatttgg attgaacata atattttcag gtgggataac
    19501 atctaccatg tattgatgca gtcccaaacc aagtccgaat tcaaccaaga taccaatgat
    19561 agaaagacaa attgtttctc gatagatgta gagcgtcact tctttattaa agaaacctag
    19621 aaccttaatg gttgataatt cgcggatacg ctctgccaca ttgatattcg ttaaattgaa
    19681 gagaacaaca aaagcaagaa gaatagaaac actaatcaaa actcccataa cacggctaag
    19741 tgagttgacg atggtcttga tttgtgcctt tagagtagta ttttggacat ccccttttac
    19801 accatcaaga gacataaatc gactggctgt ttgctcaaca tttttgtctg aatgatcttt
    19861 cagtgtaagt atcgtagcat tttggctagc ctcttttccg aaagcatcct tataagtaga
    19921 ttcgttcata aagatgaagt accccatgta catctcagaa ataccagcaa ctttgagttt
    19981 gatgtctttg tcctggctat tttgaacggt tacttcatca cctacagaaa taccagctag
    20041 gtccgccaat ttctctgaga taataatgcc tttttcagtc aaatcaagct tctgaccagt
    20101 ttcacgatga ttgagtttga tgtaattttg aagtgttttt tgatctttat cattgacaac
    20161 aagtgttgtg atatcttgac gatcgttatt acttcctaca tctaacaggt gctacggacg
    20221 gtatcggtaa gcatctagca aagaaaccgt ctagtgaagg ctatcatatc atcctccacg
    20281 gtcgcaatcc tcaaaagctg gaattggcta ctcaggaggt tcgggcagtc tccttgagag
    20341 gcagagtgtc tagctacttg gctgattttt caaaattaga taatgtttat cgatttgtgg
    20401 aggaaatcaa gcgagacttt caaaggattg atatcttatt taacaatgca ggtctgtatg
    20461 cagggaaaga gcgaaaagcg agtggtgaaa atgtcgaact aactttcatg ttatccgttc
    20521 tggttcccta tatttttata acagagctaa tccccttgtt agaaaaattg cctgatggcc
    20581 ttgttatcaa tacctcttcc tatatgcacc attttgcgaa agtgaaggat ttggactttg
    20641 gctttgagaa agaatacaat cccggtttgg cctacaataa ttccaagctc tacaccattt
    20701 ggatgacacg ctatctagca agagatttct ttttaaaagg ttcaaatacc actattaatg
    20761 cctaccatct cggcttgatt ttaaccaact tagggaataa ttctagtgat aaaaagacgg
    20821 aaaagtctct cttcggacgc ttgatgaagt ctctttcaaa agatctagat cagggaatcg
    20881 aaacaggcta ttatctcacc ttatcagagg aagtcagtgg cttgactggc tactactttg
    20941 atgaaaagaa agtcaagtcg gtatctgaaa aaggctactc atttgaaaaa acacagaaat
    21001 taatgaatta ctgccaagaa aaggtcaaaa tgtttaaaga aaagcagaat gtttaatatc
    21061 ataaatataa gaaaaaagct caagttttca ttaataaaac ttgatctttt cttatacaag
    21121 agttaataaa atcgtaatta ccagagcgat tccgatccga atcaggtagt gggctactag
    21181 atggaaattt cctttatgct tgccattcca ataggctccg tagcaaatca agctaactcc
    21241 gatcagccaa aggaataaag caacaatcgg caaaaggaag taaaggatga gagaaggtcg
    21301 caaggttgct tccgataagg agaagccgat ttcctagagt attcttgtgc tttcttaatt
    21361 ctgaaagact ggccattaaa tgaagaagag caaaagcaag ggataagaaa gctgtgaaaa
    21421 taccaagaag aatgagaagg agcatagttt tcctttctat gatacatgat gtaaagtcgc
    21481 accttagtta gaagcgacgt ttaaaatctc caaataaaac tggactactt cctgctcgct
    21541 gtaggacttg ccttttttca accaccaggt cagggtttca atgaagttgg ttataaccag
    21601 gtgcttgaga tatgagtgag gaatgttggg gtgtgattga atcagttcat cagctaccat
    21661 tggatagacg tcatgttcca gttcttttcg cagctgccgg ataaaataat cgttttttga
    21721 aagcaagaga ctggttacat ggtcttgatt tttcttgaaa tgttgaaaga tatgggccag
    21781 gtagtcttgt ggagagaggt attgagtacg ctcaaacaaa tggtgaaaga gcttttggca
    21841 gagctcatcc agtagtaact ctttgctctc ataatggctg taaaaggtcg aacgccccac
    21901 atcagccaag tcaataatct cctgaacggt gatggcctca taatcttttt ggttaagtaa
    21961 gtacaagaaa gcttgataga tggcttttct agtcttggta atgcgacgat cttgtgcagt
    22021 catatggaca ctatgaacaa actgttcagt aacgtacaca gcgaacggtt tgcccctatc
    22081 ctttctgttg gtagtattgg ataatagata ttgaatatga tgttcgtgaa tctattatac
    22141 caaaggaagg taaaaaatga gttcaaaata tgcagtctgg ttggcttttt tcttgaatct
    22201 aagcttttcc attgttgagt ttattgcagg gggaatcttt gtttccagtg ctgttctcgc
    22261 tgactctgtc catgacttgg gggatgctct agccattggc ctctcggcct ttctagaaac
    22321 aatctccaat cgtgaagaag atagtcgcta taccctaggc tacaagcgtt ttagcttatt
    22381 aggggctttg gtaacggcag tcattctgat gacagggtct ggtatggtga ttttagaaaa
    22441 tataagcaag cttttccacc cacaacccgt caatgacgaa gggcttcttt ggttgggaat
    22501 tattgctatc agtgtcaatc tgctggctag tctggtcatt cgtaagggtc agaccaagaa
    22561 tgagtctatt ctcagcctgc attttttgga agatacctta ggttggttgg ctgtcatcct
    22621 gatggccatt gtcctccgat ttacggactg gtatatccta gatcccctct tgtctcttgc
    22681 tatttccttc tttattctgt ccaaagccat tccacgtttt tggagcacgc tcaagatttt
    22741 cctggatgct gtgccagaag gggtagatat caagcaagtt aagaatgact tagagcagtt
    22801 ggataatgtt gctagtatca atcagcttaa tctttggacc atggacggct tggagaaaaa
    22861 tgctattgtc catgtttgtc tggagcatgt caaacatatc gaggtctgta aagagtctat
    22921 ccgagacttg ctcaaagaga gtggctttca aaatgtcacc atcgaagttg atgaagactt
    22981 ggcaacccac caagctcaca agcgaaatat cgaagagcta gaagcagaaa gtgagcagca
    23041 acaccatcat taaggtttgt ttttaaactc ttagagtcta cctttaagag ttattttgat
    23101 accaagttcc ctaaagtgat ccttttcatg ataaaataga acaaatgtag aacaaggatt
    23161 aattatgagt aagagagctg tgttgatgat gacctttggg tcaccagaag agattaccta
    23221 tgaagga
//
