LOCUS       gnlProkkaJHDLBKHM_68   22954 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JHDLBKHM_68.
ACCESSION   gnlProkkaJHDLBKHM_68
VERSION     gnlProkkaJHDLBKHM_68
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 15:07:52
            Original ID  :: gnl|Prokka|JHDLBKHM_68
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 27467
            Orig. end    :: 50421
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22954
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12954]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12954
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..22954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="interleaved"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..22954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     protocluster    235..21467
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10234:11467]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10235..11467
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
     CDS             403..942
                     /locus_tag="ctg12_24"
                     /transl_table=11
                     /translation="METNKPTLYWSLLMFKNWNFYIASTLKGLVFVGSQNKPIEELFEW
                     ARKRFPGSLLVEDDDKLEPYAVEITQYLEGKRKNFTVPVEYAGTQFQLAVWNALCEIPY
                     GQTKSYSDIANEINKPAAVRAVGAAIGANPVLITVPCHRVIGKNGSLTGYRGGFEMKTL
                     LLDLEKRASSEMDVPH"
     CDS             1461..2978
                     /locus_tag="ctg12_25"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGIL
                     ALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSYRK
                     YFTLFTFTTGAASMTWLSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKVSGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVTNESLAGLGEWERTGIQLLIVLAVIIPAAQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLAGISVLIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQASSAVG
                     RHEVSARTNERTSYLWVMAGRILSLVIGVAFWLTAPGEGYQFISALILGWSLSVSWTQL
                     VAFGEGRIGRIAGLTVLGGAALVYFIIHNLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     CDS             2993..5608
                     /locus_tag="ctg12_26"
                     /transl_table=11
                     /translation="MGITSVLTKDNVKKIDTDIDVQERDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQPFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQRWL
                     DSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHELEKLVGECSGLDHIENVFMQPLSSY
                     IENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERVKDWPKEAHLALQEALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLPLTNERSKKKISIAPLIAAWIHWGGLTLEEWSQMTAIE
                     QNEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGGKKSALAQLAFCIDV
                     RSEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNKIKEFADED
                     VFKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIR
                     NLREAWLRKPDTKLSLHHDTTEAEIPVGFTDEEKVNYARQALKMMGLTENIAPLVVICG
                     HGSQSINNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLAEGIQIPEDTVFAA
                     AEHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLAQLPNFQSKLKNPK
                     AEANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLA
                     NIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQS
                     VMESDHEAYHSPLRLLILIQAPREYVERLLNHDSAFLQKVQNGWVRLASLDPEGCWESW
                     "
     CDS             5685..6212
                     /locus_tag="ctg12_27"
                     /transl_table=11
                     /translation="MNVNQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGAGIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNGLTQLETMKDKIQTLDYLFQNCK
                     PEFFGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSHVKVRGLLVNHKDGKPSIMEGPDA
                     KTGQAIPDHCLS"
     CDS             6273..6563
                     /locus_tag="ctg12_28"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMECMKKLIRKAIDFYHLKSYEE
                     VEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY"
     CDS             6621..6995
                     /locus_tag="ctg12_29"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNLEKLL"
     CDS             7477..7779
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 67.7; E-value: 1.1e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg12_30"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     CDS             7906..9078
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 336; E-value: 3.8e-102)"
                     /gene_kind="transport"
                     /locus_tag="ctg12_31"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQL
                     ITIFSLVYALSTPVLMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINGKLLSGVLLIFGIASLVGSKFGGYSTDKWGVSFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLASITWVGALGVMIAIIASLLIFNSQPKQALKDINQ"
     CDS             10001..10168
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: TIGR04404"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_32"
                     /sec_met_domain="TIGR04404 (E-value: 2e-38, bitscore:
                     123.7, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNQKEWESVSKKGLMKPGGTSIVKAAGCMGCWASKSIAMTRVC
                     ALPHPAMRAI"
     CDS             10235..11467
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_33"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     1.2e-15, bitscore: 51.4, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.2e-22, bitscore: 74.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.2e-07, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.2e-06, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLDSY
                     LPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEA
                     KLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNTHDQL
                     RGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTL
                     SVGRATEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCTPGYLAW
                     YIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIELSEPDLP
                     FQKEVKAGIQE"
     CDS             11464..12954
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: skfc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_34"
                     /sec_met_domain="skfc (E-value: 4.7e-289, bitscore: 952.9,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Abi (E-value: 4.7e-14, bitscore: 46.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQF
                     IKEFVGIDVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQNQ
                     SFVVGVNANREITFFYADVPKNTLSGKFEQVSPETLKQRLMASPDGLWSRANMTGTGKK
                     EEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQVESTF
                     GVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTIVNAYD
                     ARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQIFYGIGA
                     GLISLGVTSLLFNLLEKKHYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRL
                     LMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGF
                     ICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL"
     CDS             12973..13695
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 178.1; E-value:
                     3.6e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg12_35"
                     /transl_table=11
                     /translation="MQLMQVQNLSKCYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTTT
                     IRCLTGLYKPDKGDILIEGSPPGHINVQKKVALIPDQPYLYPALTAAEHIQFRARGYHP
                     GKKDVKERVYHALKEVHLEEKANQLCGQLSRGQKQRVVLAGAIVQDALLYILDEPTVGL
                     DIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVLETADRVILIRDGKLMQDLYVPEFEEE
                     QAEWRKEVIRLLGEWSDE"
     CDS             13760..15103
                     /locus_tag="ctg12_36"
                     /transl_table=11
                     /translation="MPFLIMLLFVGAIGFQVSFVSRSTTWDMSIAGWVLTGVFILYTAF
                     GLFSNRLPSQMADIIWLYGTATSFSKVVYSVLFFSVTWKALLWIISAIFGDVLIVLLSG
                     EHINLLGRSIIFIGLFFIAEVWLMSVSCARTVKKMKRVYVSVFFLMLGIYSICLYHFFF
                     LQHSSGIWESIARFISGVGLVFDTLSPLYVVVFIGIITVSFMTIAFTSRQVEMKESLVK
                     EAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGIWSFLWLELLLFKKYLFFHSIHTVM
                     LSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSGIVRHSQSGTLHLFPGALWKKIIIL
                     ELTNTVWLYILYCVSITFMAVGNLVYWYIYGLGIYIWFMTIRLFAFTHTNRNDIKLSLP
                     QYYKSFFMALGLSGICLYVIHLLTADWYTLVVVVCIGSLSWCLFYRFR"
     CDS             15150..15665
                     /locus_tag="ctg12_37"
                     /transl_table=11
                     /translation="MNSNGDKLSLSVQNLANTNEITIVQAIGELKKSGKDAIPVLVEAL
                     KEEGSLCNIAAAVLGEFGEDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPFVI
                     KIAQESEGQSCFWASWCIAWIDPSCIEPKMYKCLKYEHEHPSGIVAPFAAEEALGKLIA
                     FQLKDKED"
     CDS             15670..16095
                     /locus_tag="ctg12_38"
                     /transl_table=11
                     /translation="MKDEQMLTEWPSHLPWLNQSQNDFTFPSDTYLLLYFWSMSCPNCH
                     QLTDKVLQDIKDMNVKVIGVHVPYIEEEKSMEVVLTYALDRGLAIPIVLDQNYEIVTTC
                     HVQGIPSFCLLSQYGQIITKTMGDVGWDKMLKKIAGL"
     CDS             16345..17322
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_39"
                     /sec_met_domain="PF00561 (E-value: 2.5e-08, bitscore: 27.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFVSLAALVLLVCVSVFIYHHFQLNKEAALLKEKG
                     TLVEVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFMPSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKYAIQNR
                     KDYEAFAAQFNTADTKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     CDS             17324..17995
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 127.4; E-value: 1e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg12_40"
                     /transl_table=11
                     /translation="MKGYHILIVEDDVMIGDLLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKELGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     CDS             17992..18978
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 57.3; E-value: 2.6e-17)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg12_41"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPMLLLAVSVLMSVIYDSMFKTMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKPADQDVIWMSNALWMQRLFDNIFQNTLKHSKAEKMEVTIEHGDVFIR
                     DDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDNGTGFLFSKE"
     CDS             19036..19299
                     /locus_tag="ctg12_42"
                     /transl_table=11
                     /translation="MNSICLKKSSKRLSTSQAVLVTDIADTGITAAVGADIIAATAAVR
                     AKEDTTTVMAAVIVTNAGATAAVNPKKVLVPLLGQGFFYVTD"
     CDS             complement(19284..20054)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 111.8;
                     E-value: 6.8e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg12_43"
                     /sec_met_domain="Pkinase (E-value: 2.1e-33, bitscore:
                     109.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LTQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLNSIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEEMEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIEEEYQHTASIREDLNRAIQSVT"
     CDS             20378..21562
                     /locus_tag="ctg12_44"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGEINQFNYSKTGVSGNSGTFSKVYRSANDRTVTDTGEETVIQSQNPYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAVFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGTDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSTQFSEEAYQKYQ
                     AAREMYEVTGYQLKDLEVIDGRYVTPEGRDLIDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIAEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGVNY"
ORIGIN
        1 cagaacaagc tctccgcgca aattttcgcc cttgtaaacg ttgcaagccc actaatgaaa
       61 aaatgcctga tagcgagtgg gttgatttaa ttactgaata cattgataaa aatttcacag
      121 aaaaattaac gctagaatcg ttagcagata tttgtcatgg gagtccgtat catatgcatc
      181 gaacatttaa aaagattaaa ggcattacgc tggttgagta tatacaacaa gttagagtac
      241 acgcggctaa aaagtatttg attcagacaa ataaatcgat tggagatatc gctatatgtg
      301 tgggtatagc taacgcgcct tattttatta ctttatttaa aaagaaaact ggacagacac
      361 cagcacaatt tcgtcaaatg agtaaaatgg aggaaacgta caatggaaac aaataaacca
      421 accctttatt ggtctttact aatgttcaag aattggaatt tttatattgc ttcaacttta
      481 aaggggcttg tgtttgtagg ttcacagaac aaaccaatcg aggaattgtt cgaatgggct
      541 aggaaacgct ttccgggaag tcttcttgtt gaagatgatg ataagcttga accctatgcc
      601 gttgaaatca ctcaatatct agaaggaaag cggaaaaact ttactgttcc agttgagtac
      661 gccggtacgc aatttcagct agcagtctgg aatgcacttt gtgaaattcc ttatggacag
      721 acgaaatcct attccgacat tgcaaatgaa ataaataaac cagcagctgt tcgtgctgta
      781 ggtgcggcta ttggggctaa tccggtatta attactgtac cgtgccatcg tgtaatagga
      841 aagaatggct cattaactgg ctatcggggc ggattcgaaa tgaagacact gctcctcgat
      901 ctggaaaagc gagcttcatc tgaaatggat gttcctcatt gaaagtgaat catctataat
      961 agggtggatt cttttagagg aaagtaaaga ccagtttact gataaacttg acaactttta
     1021 aaatttagca tatcttatac gtaacttaat aatcgatgca gatgtttatt tttcctttta
     1081 aaatatgtag gcctttagca ttcttttcat atttaatttt aaatattgat aggatgaaaa
     1141 agtatcctaa taaaaaagga agagaacatg agtcgattta tttgataatc aggactatat
     1201 taaaggaaat gaaaacatag cataaagtaa agaccaataa taaggtagca cttcaaaaaa
     1261 cttcgctgaa gttagttgaa gtgaagccga caattttcag gattcaatga tctaacataa
     1321 tcattgaaat tttgaagttg tcggcttttt tgttggaaaa aaatagagat aaataaaaat
     1381 tgaaataaat aatagacaaa tatgatctga ttgaaaggtc ttttgaacaa taatgagttt
     1441 taaaaaaggg agaatttaga atgttagttt cgctgagttt gtcatcatta ttaacattat
     1501 tttttattat gcttatggct tctgggataa gtggactatt gtttttacat ccgcgagtac
     1561 ccttgagttt tgttcgcatt catattggga tcttggcttt accacttttg gtttccttac
     1621 tgattcttgc caatagtggt gtgagtggaa atgttggccc ttggcactta gattccttag
     1681 cttgtttaat gactttcttt gttcttgcaa ttggattcat cattcagcgt ttttctgtac
     1741 gttacttaat gggggatcga tcttatcgaa aatattttac gctttttact ttcacaacag
     1801 gtgctgcttc aatgacatgg ttaagtggcg atctccgctt gatggttcta ttttggggag
     1861 caactcttgt tggtttaacc ttacttatta ggttaaacag tgcttggcaa gtggctagtg
     1921 aagcagccaa ggtttctggc cgcttatttt tgttaagttg gttttctctg tttttcgcaa
     1981 tgatgtggct ttttcatgcc acaggtcaat ggcagttatc attggttgta acaaatgaaa
     2041 gtttagctgg gctgggagaa tgggagagaa cagggattca gctattgatt gtactggcgg
     2101 tgatcattcc tgcagctcaa tggccattcc aaagatggtt ggttgagtct attgttgctc
     2161 caacccctgt ttctgcaatt atgcatgcag gtttagtaaa tgctggagga ataatactaa
     2221 ctcgattttc acctctattt catggtggta tcgcttcgat tatcttactt ctgcttgctg
     2281 gcatttctgt attgattgga actggaatta gtttagtcca ggttgattat aaacgccagt
     2341 tagtaggctc cacgattgga caaatggggt ttatgctcat tcagtgtgca ttaggcgcct
     2401 atatagcagc cattattcat cttattttac atggtttatt caaggctacg ttgtttctac
     2461 aagctagttc agcagtaggg cgtcatgaag tatcggctcg tactaatgaa agaacatcct
     2521 atttatgggt catggctggt cggattttat ccttagttat aggtgttgct ttttggctca
     2581 ctgctcctgg agagggatat caattcatta gtgcgctgat cttagggtgg tcattgtccg
     2641 tttcttggac tcagcttgtc gcttttggag agggccgaat tggccgaatt gccggcttaa
     2701 ctgttttagg aggagcagcc ctcgtatatt ttatcattca taaccttttc tataagtggc
     2761 tgcatacaac catttttcaa agtgttcaac ctccaatgtc agctgtcatg attgtcgtat
     2821 gtctcttact ctttggcagt gctttaggta cgtgggttgc tcgtcatcgt tcttccgttt
     2881 ttttcgcggt actctatctt tggttagtcc gattaggtga agcaaaacca aagtcagtag
     2941 agagtcaccc agactacctt aaacaatata tttcataagg agctaatctg agatgggcat
     3001 tacatccgta ttaacgaaag ataatgtaaa aaagatagat acagatattg atgttcaaga
     3061 aagggatctt aacgttttca ttacatctgc cagccgagtg attgcgccac tttggcctat
     3121 ttctacattt gctgcacgta atccgtggat gggacttgaa aaccaacctt ttgatcaggt
     3181 tgcaagttgg ttgaaaaaca ctcgcgatgt tgatatatac cctagtgcgt ctatgatccg
     3241 ttcagcaaag aataaaggtg agattgatga agattttgtg gaaatggggc tgcagcgttg
     3301 gcttgattca cattcctatc acatcccacg ggacgtagca gagcgatttt gtcatgctgc
     3361 attaaagtta gatcccctgc cttccgacct tttatcatca catgagctgg agaaattagt
     3421 aggtgaatgt agtggattgg atcatatcga gaatgtgttt atgcagccac taagttcgta
     3481 tatagagaat caagatggtg aaaggctagt caatatacta gatcatcatg tcattaagtg
     3541 gagtaaatta tatcttgatg actctcaagc aggctggaca atgcctaatc gtgaggaagg
     3601 tttctatcgt gcttggcagc atctcattca atatgatcca gcacttagca aaaagcagcg
     3661 agaaagggta aaggattggc cgaaagaggc acatttggct ttacaggaag ccttattcgc
     3721 actagaaatc ccagagtcag aaatccagac ttatcttgaa ggtcatttac tttcattacc
     3781 tggatgggca gggatgatgc tttggcgctc ccagcaatcg agccacgaac atgcactcct
     3841 aacagaatat ttagcggttc gaatatccat ggagtgggct cttataaagc catacttacc
     3901 tttgactaat gaacgatcta agaaaaaaat ttcaattgct ccccttatag cagcttggat
     3961 tcattggggt gggcttacat tagaagaatg gtcacagatg acggccattg aacaaaacga
     4021 atatttatca tttgcctaca gctttgatga gaaacttcgc aagaaacttt ggttagaagc
     4081 ttgggagcaa acgtacactg atcgattaag ccagaagatc atctcgaaac aacgtgaaac
     4141 cggcggtaaa aaatctgcat tagctcaatt agcattctgc atcgatgtac gatcagaacc
     4201 ttttcgtcgt caactagaaa aagaaggccc gtttgaaacg attggtattg ctggtttctt
     4261 cggggtgccg attgcaactt gtgaacttgg cagtaaacac agtcatgctt ccttgccgat
     4321 catacaaaaa ccgcaaaata aaataaaaga gttcgcagat gaggatgtat tcaaaaaata
     4381 caatcaacgg aagcaagcaa ttcattcttt aagccatacc tttaaaacga tgaagcagaa
     4441 tgcgctttcg agcttactac tgcctgagct aagcggacct tggcttactc tgcaaatggc
     4501 agcccgtagc tttgtgccaa gaaaggcggg tcgtttcatt cgtaatctcc gtgaggcttg
     4561 gttgcgcaaa cctgatacaa aactctcgct tcatcatgat actacagagg cagaaatacc
     4621 tgtgggtttt actgatgaag aaaaagtgaa ctatgctcgc caagcattaa aaatgatggg
     4681 gttaacagaa aacatcgcac ccttggtcgt gatctgcggg catggcagtc aaagtattaa
     4741 taatccttat tccgcagccc ttgattgtgg tgcctgcggt ggagcggccg gtggattcaa
     4801 tgctagagtt ttagctgctt tatgtaatct atcagaggta cgagaagctc ttttagctga
     4861 aggaattcaa attcctgagg atacggtttt tgcagcagct gaacataata caacagtaga
     4921 tgaattacat tggctttatg taccagagct ttccgaagct gcacaagaag catttgaaca
     4981 aattgaagcc gtgatgccga aagtgagaca tcatgtaaac gcagaacgtc tagcccaatt
     5041 accgaatttc caatcgaagc taaaaaatcc gaaggctgag gcaaaccgat ttgcggaaga
     5101 ttggagtgag atacgtccgg aatggggact ggctcgtaat gccgctttta ttatcggtaa
     5161 acgtgaacta actcaggatt gtgatttgga aggcagagcc tttctccata attatgattg
     5221 gaagcaggat gaaagcggtg aactcctagc aaatattatt gcaggacctg gtactgtagc
     5281 ccaatggatt aatttacaat attacgcatc aacggtagcg cctcattatt atggcagcgg
     5341 aaataaagca actcaaaccg ttactgcagg tctcggcgtt atgcagggga atgcaagcga
     5401 cttgttagcc ggactgcctt ggcaatccgt catggaatca gatcacgagg cctatcattc
     5461 tcctcttcgt ttattgatac tcatccaagc acctagagaa tatgtagaac ggttattaaa
     5521 tcatgactca gcatttctgc aaaaagttca aaatggatgg gtccgactgg ctagtcttga
     5581 tccagaagga tgttgggaaa gctggtaatg atgaatctaa gcatttatca aatggatttg
     5641 ttactcaata caaaaatgat aaacataagg aagaggtgtg ctgtatgaat gtaaaccaaa
     5701 ataaaaaagt attatttttg acggatattg aaaacggttt ggagcctatt ttacaagaag
     5761 cgactaacac ttctgcagag aatatgttga ctatacaaag ctatggtgcc ggtatttcac
     5821 atccttatgg agaaatcatg aggtctgtta tttttgcgat ttaccaggaa gatgttgagg
     5881 agatttttgt agtaggaaca aaagataaga agacttccgc aggtaatgga ctaactcaac
     5941 ttgaaacaat gaaagataaa atacaaacat tggattatct ctttcaaaat tgcaagcctg
     6001 aattttttgg tggtacggtc gatgaatggc taaatgaaaa tagcagtgac accattgaaa
     6061 aaagtgttga tatgattcga catcacccac tagtgccgtc acatgttaaa gttcgaggtt
     6121 tactcgttaa tcataaggat ggaaaaccct caattatgga gggtcctgat gctaaaacag
     6181 gtcaagccat acctgatcat tgcttgtcat gatgaaatgc aggttcaact tctaaacacc
     6241 atatatggag aaagcagttc taaggagatt gtatgagcgc taatttaact gattttgtca
     6301 cgaaaacaat agaggacatg aactcgtttg atcgtgaaaa tatggaatgt atgaaaaaac
     6361 taattagaaa agcaattgat ttttatcatc ttaaatctta tgaagaagtt gaggaaaccc
     6421 attcaggaaa tgttcgattt ttgcatgtcc actctatgat ggaagaaaat atgttatcca
     6481 aaatgatagt ggtcacaaga aacggtaaaa ctgatttgga tattgaaggt gtatatgaag
     6541 gatatgttgt aagagaatat taatgagacg aaatcacaag tagaatatgc caattttttt
     6601 gctcaggaga tgtattagat atgaaaaagt cgaagggttc tattgaatca gagatcagta
     6661 agtccattac tcaatgggag aaggattatc ttgggcgggg gtctgtatct gttaagactg
     6721 atatactgcg ggacatgatc atcgtcaatt taaaagggat tttaacacca gctgaatatg
     6781 tagtttgtgg atcaaaagag ggtatgttat ctatcaaaca aactcgttcg gagttagtcg
     6841 aatcaggtat agaaggcctt aaggatatta tcttaaaaat aaccggagaa aaagtgaaaa
     6901 gttttcatac tgatttaagc tcccggacag gtgaacgagt gatggtgttt aaattatgta
     6961 atgatctaga gaaaaatttg gaaaagctct tataatctaa agaaaataaa tgttttgacg
     7021 gtatggaatt tgttgtgaat tgaacataat gaactgccga ttcttttgtt ttacaattat
     7081 ggcatcattg ataactttta ttcatatcct aagcggacat aaagagatgt caattcatag
     7141 tatactgtct tgttattcct gtcgaaagat ctaacatccg ctgttgttat gagcggatgt
     7201 tttttacatc taaatttgct gctggtgatt agtcacttga acaataccaa attcatttta
     7261 attgaaaaca tccttgtcac ctgctgggtt cctccaagtg tttagtgaca tgattatgag
     7321 accaatttcg taaagcttga tgataaatta agcggtgaac aaaattgata tgctgtcttc
     7381 agtttcattt cacggaatta gtcagagata aacctttaat taaatatatc caaaaaacgg
     7441 attgacatat cgaaatataa cgatataata atcgatatgg aaccaattga agtattcaaa
     7501 gccttatcaa atgaatcaag gctgcaaatt ttacaatggc tgaaggagcc cgatcgtcat
     7561 tttgcacccc atgaagggat tgatatgaac acaatcgggg tatgtgtcag tcaaataaca
     7621 gacaaattga aaatgacgca atcgacagct tctcaatatc ttaccatcct tttaagagcc
     7681 ggcttgatta aggcggagcg tattggaaag tacacatatt acaaaagaga tgaagaagcc
     7741 attgggaaac ttgctgactt tcttaaaaca gagatataaa aataaacatc aaaagatgtt
     7801 tatttttaca ccatacatat cgacatatta cgatgtgttt attttttata ataacatatc
     7861 gataattcgt gatatgttta ttaataatta aggagtgaat gttttatgtc taacacttgg
     7921 aaaatttata ttttagccat tgtcagcttt ttagttggaa cctcagagta catcatttcc
     7981 ggaattttgg atcaaattgc tcatactctc gggatcactt tagctgccgc gggccagctt
     8041 attaccattt tctcacttgt atatgctctt tctacacccg tacttatggc gttgacagca
     8101 agtatggata gacgcaaatt gatgatgtat gccctaggtt tgtttgtgtt cggtaatgtc
     8161 ctggcttttg tactgcctgg ttatggatgg tttattgcag cgcggatcat tatggcgatg
     8221 ggagcaggtg tggtggttgt caccgcctta acgattgccg ctaaaattgc atcggaaggg
     8281 aagcagggaa gtgccatcgc tacggtcgtg atgggattta ccgcttcttt aatcattggt
     8341 gttccgcttg gaagaatgat agcagtagca ttaggctgga agtctgtatt tggagcaatt
     8401 gctttgttgg gattgatcgc aatggtcgtt attttcttta cccttccgca tactgaaggg
     8461 gataagcctg tgcctttgct tcaacagctt gctcttttca aaaaacggaa agtggctatg
     8521 ggattatcaa tcactttctt ctggctcggg ggatattctg ttgcttacac ttatttgtca
     8581 ccgtatctct tgaacatctc aggtataaat ggcaagctgc tcagtggtgt tttgcttata
     8641 tttggaattg ccagtttggt tggatcaaag tttgggggat atagcaccga taaatgggga
     8701 gtgtccttta cactcgttgg cgggatgacg ttgcatatcg tcacactgat tcttctgtca
     8761 cttgttactc attcctatat cggagtgttg gtgattctca tattatggtc gtttgccgca
     8821 tggtctaccg gtccgacaca gcaatttcac ctggctacaa tagaaccgga aatgtcaggt
     8881 gttttgctta gcatgaatca gtcaatgatg caattcgcca tggcggtcgg cgcaggtata
     8941 ggaggggttt ttgtggaaaa cgtatcattg gcctcgatta cctgggttgg tgcgttaggg
     9001 gttatgattg ccattattgc atcattgctg attttcaatt cgcaaccgaa acaagcgcta
     9061 aaagatatca atcaataatt tcgaaagatc taacatccgc tcgttataca agcgggtgtt
     9121 ttttataagc attcaaagtc agtccatgca tgagccttcc aagggccgac atcgttctgt
     9181 atgtgtcgaa ggcgcactga agctgaaagg gatttcttaa ggctttgccg ctgaagtacg
     9241 gtacgattgc cttgatcgaa cactggaaac acaagagagc gtaaacctga acattcgcgt
     9301 aaacgtcaag gaagttgcca cttggggagt aaacacttgc atcatctcgc tgaaaggcct
     9361 agacaatgcg gatgacatat tcgtattgcc ggaagtaaac acagcgcttg ctctgtttcc
     9421 gttggtttct gttgtcggtt gcagctgatt gcttactaat gatgccctgc atctcggttg
     9481 tgatgtcgat aagcagcgta accttgtgaa gagtgttact gtggagtaag atgtttaacc
     9541 cctttggata ttttagccga aggggttttt agtatagata tttgatttaa attacaggag
     9601 acttcattca tttaactaaa gtcattgctt tcttaatcac taaagtttat ttgaaaataa
     9661 tctcttgatt tattttcctc gaagagattg tttgtcaatc tattaggcat cagaattttt
     9721 ataacagaat ggatcgtctt tttgacgttt tgtttataga acaagaaaat attcaaaaca
     9781 taagtgaaaa attaggggtg agctcctgtt tttctcgaga ggatagcttg tcagcttttc
     9841 tatttttaaa gggttaaaat attctattta tactaattaa tgtaattttt aggataatat
     9901 acaaaatccc ccttacttcg acaattgcaa tctggtatta tcgtatcgca tgggagctat
     9961 gtcaatagac tctatgcaaa aattgagagg aggtttactt atgaaaagaa accaaaaaga
    10021 atgggaatct gttagtaaaa aaggacttat gaagccggga ggtacttcga ttgtgaaggc
    10081 tgctggctgc atgggctgtt gggcctcgaa gagtattgct atgacacgtg tttgtgcact
    10141 tccgcatcct gctatgagag ctatttaaca tttgagaata gggagttgag cgtatttgct
    10201 tatactcctt attttctctt aagggggatt ttatatgtca tatgatcgtg ttaaagattt
    10261 tgatttgcca gagttagcgg ttcatttaca gcctcatggt gctgtaatga ttgatagaaa
    10321 aagtatgttt tatttcagac tcagtggacg tggagcacag ttggcgtttc tgttatcaaa
    10381 aaacaaaaac cttcataaaa cggcacgtat ttgggagatt atgaaaaaag aagagatgag
    10441 tgctgaccaa ttaaaagaag agcttagtgc ccatccattt acggaggctt ggacggaagg
    10501 gctgttagat cagcctttac acgtttcggg ttcgctagat tcatatttac ctattagttg
    10561 taccttgcag ttgacaaatg cttgtaattt aagctgttcg ttttgctatg ccagctcagg
    10621 taaaccatat cctgaggaac tatctagtga acaatggata ttggttatgc aaaagttagc
    10681 agcccatgga gttgctgata ttacgctgac cgggggtgaa gcaaagctga tcaaagggtt
    10741 taaagaatta gtcgttgttg caagttcgtt gtttaccaat gtgaatgtat ttagtaatgg
    10801 attgaactgg cgagatgaag aagttgaatt acttagtcac ttaggcaatg tttctgtaca
    10861 gattagtatt gatggtatgg ataatacaca tgaccaatta agaggcagaa aaggcggctt
    10921 taaagaaagt atgaatacca ttaaaaaatt atcagaagca aacattccag tgattgtcgc
    10981 tatgaccatt aatgagtcca atgctgatga agtatcagat gtggtggagc aatgtgccaa
    11041 tgcgggtgct tttatctttc gtgcaggaaa aacgttatct gttggacgtg cgacagaagg
    11101 ctttaaggct ttggatattg attttgaaga aatggttcaa atacagctta gggaagcacg
    11161 tcataaatgg ggagatcgcc tgaacataat tgattgggag cacgaagaga gttcgttcac
    11221 aacagatttt tgtacaccag gatatcttgc ttggtatata agagcagatg gatacgtaac
    11281 tccttgccaa ttagaagatt tgccgctagg gcatatttta gaagatagca tggctgacat
    11341 tggttcacct gctcgtttgc ttcagttaaa atgtgaagct aaaaattgca aatgtatagg
    11401 gaaaattgag ctatctgaac cggacttgcc ttttcaaaaa gaagtcaagg cagggattca
    11461 ggaatgaata gtctatcatt ggtgttctgg agtattttag cagttgttgg attactgtta
    11521 tttattaaat tcaaaccccc aacaattgct tcactactct taagcaaaga tgaggcaaaa
    11581 gaaataagca ttcaatttat aaaagagttt gttgggatag atgtagagaa ctgggatttt
    11641 tattcggtat attggtatga ccacgataca gtaaataaac ttcatcactt aggcatactt
    11701 aagaaaaata gaaaggtttt atatgatgtt gggttggtcg aatcatggag agtccgtttc
    11761 gttcaccaga atcaatcatt tgtagttggt gtcaatgcca atcgagaaat cacttttttt
    11821 tatgcggatg ttccgaaaaa taccctttcg gggaagtttg aacaagtttc tccagagaca
    11881 ctcaagcaga ggttaatggc ttcacctgat ggactttggt ctagagcaaa tatgactggt
    11941 actggtaaaa aagaggagga ttttcgcgag gtcagtactt attggtacat agcggaagcg
    12001 ggagatattc ggctcaaggt gactgttgaa ttacagggcg gccgaatttc ttatattggt
    12061 actgaacaag aaatactaac agatcaaatg agtaaagtca ttcgagatga acaagtggaa
    12121 tcgacattcg gagtatctgg tatgctgggt tcagctttag cgatgatcct tgcgattctc
    12181 atccttgtat ttatggatgt gcaaacaagc ataatcttca gtcttgttct gggtttgttg
    12241 attataatat gccagtcatt gacgctgaaa gaagatattc aattaacaat tgtaaatgct
    12301 tatgatgcaa gaatgagtgt caaaacggtc agtttattag gtattttgtc tacacttctt
    12361 acaggattat taacaggatt tgtagtattt atatgttcat tggcaggaaa tgcgcttgct
    12421 ggtgattttg gatggaaaac gtttgaacaa ccaatagttc agattttcta tggaatagga
    12481 gcagggctca ttagtttagg agtgacttct ctgctgttta acttattgga gaaaaagcat
    12541 tatttacgaa tttcacctga gctttctaac cgaactgtct ttctatcagg ttttaccttt
    12601 aggcaaggat tgaatatgag catacaaagt tcaattggag aagaggtcat ctatcggcta
    12661 ttaatgattc cagtcatttg gtggatgagt ggaaatatcc tcatctccat tattgtatct
    12721 tcctttttat gggcggtgat gcaccaagta actggatatg acccaaggtg gatacgttgg
    12781 ctgcatctat ttatattcgg ttgctttctg ggagttctct tcatcaaatt tggttttatt
    12841 tgtgtattag tagctcattt cattcataat ttagtactcg tctgtatgcc gctgtggcag
    12901 ttcaagcttc agaaacatat gcatcatgat cagccaaagc atacttcact ctaatgatta
    12961 ggagaagatt tgatgcaatt gatgcaagta caaaatttaa gcaaatgcta tcgaaatggt
    13021 gatggggttg aacatttgtc tttctcaatt caacgaggag aaatcgtggc gctattgggg
    13081 ccaaatggag ctggaaaaac aacgacaatt cgatgtttga caggtctcta taagccggat
    13141 aaaggagata tcctcattga gggttctcct ccaggacata taaatgttca aaaaaaagtc
    13201 gcgcttattc ctgatcagcc atatctgtat cccgctttaa ccgctgctga acatattcag
    13261 tttagggcaa gaggatatca tccaggtaaa aaagatgtaa aagaaagggt ttatcatgca
    13321 ttgaaggaag tgcacttgga ggagaaagca aaccaattgt gtggtcagct gtcaagaggc
    13381 caaaagcagc gggttgtcct ggcgggggcg attgttcaag acgctttgct gtatatatta
    13441 gacgaaccga ctgtgggcct tgatatccca tcaaaacagt ggctctctaa ctggttaaaa
    13501 actaaaaccg atcaagggtg ttcagcattt gtatcaactc atagtctaga gtttgtttta
    13561 gagacagcag acagggtgat attaattaga gacggcaaac tcatgcagga tttgtatgtt
    13621 cctgaattcg aagaagaaca agcggaatgg agaaaagaag tgattcgtct tctgggggaa
    13681 tggtcagatg aataatatca tttctttttt atggcttcag tcaaaaaggc gttttgtcag
    13741 tcaaggtcag gaaaaaaaaa tgcctttttt gatcatgctc ctttttgttg gggccatcgg
    13801 atttcaagta agttttgttt ctagatctac gacatgggat atgagtattg ctggttgggt
    13861 acttacaggt gtttttatcc tttatacggc atttggactt ttttcaaatc gattaccaag
    13921 tcaaatggca gatattatat ggctttatgg cactgccaca tctttttcaa aagttgtgta
    13981 tagtgtttta tttttcagcg tcacttggaa ggcgttgctt tggatcatct cagccatatt
    14041 cggtgatgta ttaattgtgc ttctgtctgg tgagcatatc aatttattag gccgatccat
    14101 aatttttata gggctctttt ttatcgctga agtgtggttg atgtcggtct cctgtgccag
    14161 aacagtgaag aaaatgaaaa gggtatacgt ttcagtcttt tttctaatgt taggcattta
    14221 ctccatatgt ctttatcact tcttctttct ccaacattca tctgggatat gggagagcat
    14281 tgcccgtttt attagtggtg ttggattagt gtttgataca ttgtcaccgt tgtatgtggt
    14341 tgtatttatt gggatcatca cagtctcttt tatgacaatt gcttttacga gccgtcaggt
    14401 agaaatgaag gaatcgttgg tgaaagaagc tgaattctgg gaggaatttc aagaacgtca
    14461 atttggttca gggcaaatta tacagaaacc aaaaacgact tggtggggct tgcaaggtct
    14521 aaatggcatt tggtcttttc tgtggttgga actgttgctt tttaaaaaat atttattttt
    14581 tcatagcatt catacggtca tgctcagtgg cgtcttttat gtcgtcattt tcatgtatcc
    14641 agaatggttt tatcttcttt tctttcttat cgtctcggca gtcatgttaa gttcctatta
    14701 ttcaggaatt gtcagacatt ctcaatcagg cacccttcat ttattccccg gtgccctttg
    14761 gaaaaaaatc attattctag agctgacgaa tacagtctgg ttgtatattc tttactgtgt
    14821 ctctattact tttatggcag ttgggaattt agtttattgg tatatatatg gcttagggat
    14881 atatatatgg ttcatgacaa taaggctttt tgcttttacc catacaaaca gaaacgatat
    14941 taagctttca ttgcctcaat attacaagtc attttttatg gcattaggcc tgagcggcat
    15001 ttgtttgtat gtcattcatt tattgactgc tgactggtat acattagtgg tggtcgtctg
    15061 tatagggagc ctaagttggt gcctgtttta tcgtttcaga tagtggttat gtagagttat
    15121 tgttttaaaa cgaggagagg ggctctttta tgaattcaaa tggtgataaa ttgtcgttat
    15181 ctgttcagaa tttagcgaat acaaatgaga tcacaattgt tcaagcgata ggtgagctaa
    15241 agaaatcggg aaaagatgca ataccagttt tggttgaggc cttaaaagag gaaggctctt
    15301 tgtgtaatat tgctgcagct gttttaggtg agtttgggga agacgcgagt gaagcagcgg
    15361 aggagctatc atgtttatta aaaagtcatg ccgaagatac aagaatggca gcggcgattt
    15421 cattaatgag aatcgggaag cccagtctac cctttgtcat caaaatcgct caagaaagtg
    15481 aagggcaatc gtgcttttgg gcatcttggt gtattgcatg gattgatccg tcttgcattg
    15541 aacctaagat gtataaatgt ctaaaatacg agcatgaaca tccttcagga atagttgctc
    15601 cgtttgcggc tgaagaggcg ttaggaaagc tgattgcttt tcagctgaaa gataaggagg
    15661 actgaaagga tgaaagatga acaaatgttg actgaatggc caagtcattt accatggttg
    15721 aatcaatcac agaatgattt tacatttcca agtgacacat atcttcttct ttatttttgg
    15781 tcaatgagct gtccaaactg tcaccaatta acagacaaag tccttcaaga tataaaggat
    15841 atgaatgtga aagtaatcgg agtacatgtc ccctatatag aagaagagaa atctatggag
    15901 gttgtcttga cgtatgctct tgatagggga ctagctattc cgattgtatt agaccaaaac
    15961 tatgagatcg tcacaacttg tcacgtacaa ggcatcccca gcttttgtct attaagtcaa
    16021 tacggtcaga tcattactaa aacgatggga gatgttggtt gggataagat gttaaaaaag
    16081 attgcaggct tgtgaaattt tacgtcttgt atgtgcgaca aacggttgaa tattatgatg
    16141 aaacggtcct tcctataagc aggaaggttt tttaatgaaa tattttttta ttagtaggta
    16201 aattcatcaa atgttctgct atgctccaaa tgtacacctt tccgtaaggg caaagttaaa
    16261 tgtgaaaata aaactgttcc aaagttaatc agttatttat tttcataccg tatcctttca
    16321 gtatcacggt gaaaggagca tcatatgaaa acattatgga aagtcctcaa aattgttttt
    16381 gtcagcttgg ctgctttggt tttgcttgta tgcgtctcgg tatttattta tcaccatttc
    16441 cagctaaata aggaggcggc actccttaaa gaaaaaggca cattagtcga agttgatggt
    16501 aaaaagatga atgtgtatca agagggaagc gggaaggata cgtttgtgtt tatgtccggt
    16561 tcggggattg ctgcgcctgc ttatgaaatg aaggggctgt acagcaagtt ttcaaaagaa
    16621 aataagattg ctgttgtaga tcgggcaggt tatggataca gtgaagtgtc tcacgatgac
    16681 agagatattg atacagtatt ggaacagacg aggaaagcgc ttatgaaaag cggaaataag
    16741 cctccttata ttttaatgcc tcattcgata tccgggattg aagcgatgta ttgggcacag
    16801 aaatatccta aggaaatcaa ggccattatt gcgatggata ttggattgcc ccagcagtac
    16861 gtcacgtata aattgagcgg agttgacaga ttgaaagtga gagggttcca cctgttaacc
    16921 tcgattggtt ttcatcggtt tatgccttcc gctgtatata atcctgaggt gattcggcag
    16981 tcgtttttaa ctgatgaaga aaaagaaatc tataaagcca ttaactttaa gcaatttttt
    17041 aatgcagata tggaacatga gcttttgcag tcttaccaaa acggcagcaa atctgtgaat
    17101 ctgccggcgc caaaggaaac tcccgtcttg attttagatg cggtctctga ccaaaataga
    17161 cattcaaagt atgctataca aaacagaaaa gactatgaag cgtttgcggc tcaattcaat
    17221 actgccgata caaaggaact gaggggaaca cacagtattt atttatatca gcctgatcaa
    17281 atatataaac tgtccatgga gtttatgaga aaggttcgct aggatgaagg gttatcatat
    17341 tttaatcgtt gaagacgatg tgatgattgg tgatttgctg caaaagattt tgcagcgtga
    17401 gggatatcgt gtgatatgga aaacagatgg agcggatgtg ctttcggtga ttcagaaggt
    17461 ggatttggtc attatggatg tgatgctgcc gggtgaagac gggtatcaaa tgtctgcaaa
    17521 aatcaaagag ctggggctgg gcattccggt tatttttctc tcggcccgca atgacatgga
    17581 cagcaagctt caaggtttgc agatcggcga ggattatatg gtaaagccct ttgatccgag
    17641 agagctgcta ttaagaatgc ggaatatgct tgagcatcat tatgggacct ttacgcaaat
    17701 caaacatttg tatattgatg cggtaacgaa aaaagtgttc aatgaaagcc tgcatgatga
    17761 ggtattgttt actgcgattg agcggaaaat tttcttttat ttatatgaaa atagagacag
    17821 tatcctgaca aaggaacatt tctttgaata tctatggcag ctcgaagata gaaacccgaa
    17881 tattgtcaat gtgcatatta aaaaaatcag agctaaaatc aatgatcaag cgggtgagat
    17941 gattgaaaat atatatggag aagggtatcg gctgaatacc gttgtgaaga aatgaagctc
    18001 aagacaaaat atcagttgtt attgtttacg gccgtcatta gtgttccgat gctattgctg
    18061 gcggtcagtg ttttgatgtc tgtgatttat gacagcatgt ttaaaacgat gaatcatggt
    18121 atgccctttc acaggtcgtt tgcgtacccg gcaatgatcg ttgtattttt gatatcactc
    18181 ttattgttag cttttttatt ttcaaagtcg attcattctc tgttgcataa aatcaatcta
    18241 ttaaatcaaa ccattcggca tttggcgagt gatcaaaggg tacccgataa aattgaagtg
    18301 aagcgtgctg atgaaatcgg ggaactgatc aagtcggtca atttgttaat tgaacggacg
    18361 acatatcgtg aactggagct gagacagcag gaggaaatca aaaaggagct tttgcaaaaa
    18421 ctgcggcatg acattaatac acctttaacg gctctcaggc tgcagttatt ttatttggaa
    18481 gaccaatgtc atggtcaggc tgtattcgaa tcattgtatc agcaaatcga atatatctcg
    18541 gaattaacca atgaattcaa tctatattcc gctgagacgc tggaaagctc ttatattgta
    18601 aatgaagaag tgcgtctaaa cgagctatta gaaacagcgg taaaaaagtg ggattattta
    18661 tacagtatga gtgggattga gctgcactat aagccggcag atcaagatgt gatatggatg
    18721 agcaacgcgt tatggatgca aaggctgttt gataatattt ttcaaaatac gttaaagcat
    18781 tcaaaagctg aaaagatgga agtcacgatt gaacatggcg atgtttttat tcgtgatgac
    18841 ggtattggat ttgatcggaa tgagagcagt gagggacttg ggttaaagat tattgaggat
    18901 acatgcaggc tgcttgcgat tacttatgag ctgcatacaa atgataacgg aacggggttc
    18961 ttgttttcaa aagagtgacc ccgctgatgt ttttctttct cctataaaat ttatataata
    19021 ggagaaagaa atggggtgaa cagcatatgt ttaaaaaaat catcaaaacg attaagtacc
    19081 tctcaagcag ttctagtgac cgatatcgca gacaccggca ttacagcagc agtcggcgca
    19141 gacattatcg cagctacagc agcagttcgg gcaaaagaag acactacgac cgttatggcg
    19201 gcagtcatcg ttacaaacgc cggagctaca gcagcagtta atccaaaaaa agttcttgtt
    19261 ccgcttttgg gacaagggtt tttttatgtg accgattgaa tggcccggtt tagatcctcg
    19321 cgaatggaag cggtgtgctg atactcttcc tcaatgccca ataatctttt cagcagcaag
    19381 gttacttcct ttgtcagtgt taattcctcc agccaagtgc cgtttttctt cttttttcct
    19441 ttatattgag agtacagcag gaataacagc gtttctccga gatcgaagaa gtcatcctgt
    19501 tttcgtacct ttatttcctc catttcttca ggagtcaatt gtttggcaag gccgaaatcg
    19561 atgaggcaga gcctgccgtc attgatgatg atattaggcg ttctgatgtc gctgtggaag
    19621 ataaggcgat catgcaggta ttctataatc tcaagcagct gcgaaatcag ttgtaatgcc
    19681 ataagctctg tgaacggctg ttttcgaaaa aataataatt cttctatatt ctctccctca
    19741 atgaactgca tgacataata agcctgtccg tctatgatga actcatctat gaagcccgga
    19801 atttgcgggt ggtgaatgct attgagcagt tttatttcct gttggaatcg gactttctct
    19861 ttttcctttt tcgcttttgt cggccgaagc tgttttaaga cataaggtgt ttgagttagg
    19921 atatcggtgc acaaataaac caaaccgtag cctcccatac cgaggcactc ttcgattttg
    19981 tattgatgat ttaagataac gccgttcttt agagggcggt caaatagcag tttttttaga
    20041 agttttaatg ccatgtctgc acttcccttg gttgtactga ttatagttta ccttctagac
    20101 ggagaataaa aaagagccgg ataaccggct cggtataagt taaaactgct ttgttacgtc
    20161 gtattcataa tctatttttg cttttacgtt gctcatcgtc gatctggctg tcgctaatgt
    20221 attatattta aaactccata cctttgccac actgagttga tctgacaaag agatatcata
    20281 agaccctatt tatgtaaata aatgtttttt gaggttaata tatacattat atttgccgat
    20341 aaaaaagaat aagagagaat actcgggagg gaattcaatg cgtctgaatc ggcaatttat
    20401 ccgcactcag ctgatggcac agaacatatt gagcaagaat gcgcctgcca aacgggagaa
    20461 tgcgactgaa aatccagcag cagttctgga aaaggcatac agcaggctta agtcacaatc
    20521 ttcaactggg gaaatcaatc agttcaatta ttctaaaacc ggcgtgtcgg gaaacagcgg
    20581 gacgttcagc aaagtgtatc gatcagcgaa tgatcgaaca gtgacagaca caggggaaga
    20641 aacagtgatt caatcccaaa acccctatga atctgagagt gatatcagaa tcaaaatact
    20701 agatgaaaaa tacagcagga tgaatgcgat taacaaaaca aagtctgatc cattaggcta
    20761 tattaaggat aagtaccaaa attcaaagtc tccttatttc agaagtgatc tgtcagctgc
    20821 agaaagacag gccgcttacg ataatgaaac agaatggtta ttcaaaggga aggcgcaaaa
    20881 ctataacctt caggatgctg tgtttcggaa tgtcacattt catggggaag tggaagctga
    20941 gaatgaaaag gtgtatcagc ggggacaggt taaccagcag ctgcaagtgc tgttgaatcg
    21001 aaaccatatt catattccag aggggacaga gctgacgttt acaatcacac cgattgacta
    21061 tcaggtgcgg gtaagcggga cagacgatca ggatctgatc aagcaaattg agcaagtgct
    21121 gcaatctgga gacaacagca aagaactatt tttgcacatc atgaaaagcc aaagcagtga
    21181 ttcaacacaa ttttccgaag aggcctatca aaagtatcag gcagctcgtg agatgtacga
    21241 agtcacaggc tatcaattga aggatttaga agtcattgat ggacggtacg tcacgcctga
    21301 gggacgtgac ttaatagatg tatataagga agaacttgaa aaagatccag tacagaagca
    21361 aacggcttct tatgctatat cttactatcg ttcagagctc agtaaaatcg cggaagccgg
    21421 gtataatgcc attccggatt tcatcctatc aattgattac agcaatggat ctctgagaga
    21481 tgtgggacaa agcaagagct atgggaccgg agataccggg tggcttgaag cattaaagcg
    21541 tcaaacgggt gtgaattatt aagtaagctg ttcatgtaga acagcttatt ttttatgaga
    21601 atctaagggg tgtattaatt tcaatattca aacaatttta ttatttttat ataaaagatt
    21661 ttaaaagaag tgaacgattc aaaactctga acaaaggtgt ttacctgaaa aaaacaattg
    21721 tattttccag agaaatttat tatgatgaaa taagtaattt aggagattat ataacaattc
    21781 taagtttgaa ttttctgatt gttatcactg attcatgtga aggcaagcag gtctgctgtt
    21841 ttctcattta ttagtatttt gttaggagga ggaagaggag tggcaaataa agaattaaag
    21901 aggggcctgg gcgcgcgcca tattcagatg atcgccttgg gcggtacaat cggtgttggc
    21961 ttgtttatgg gttctgccag cacgatttca tggactggcc catctgtcct tctggcttat
    22021 gcaatatgcg gaatttttat cttttttatt atgcgtgcga tgggtgaaat gctgtatgtc
    22081 gagccgagca caggttcttt tgcgacgttc ggccatcaat atattcatcc gatggcaggt
    22141 tatataacag catggagcaa ctggttccag tggattatcg tcggcatgtc agaaattatc
    22201 gctgtcggtt cttatatgaa gtattggttc ccggatttgc ctgcttggat acctggtatc
    22261 gtggcaatgg tgattcttgg tgcggcgaat ttaatttctg ttaagtcgtt tggggaattt
    22321 gagttttggt ttgcgatgat taaaatcgtg acgattatct tgatgattat tgcgggaatc
    22381 ggaattattt tcttcggttt tggcaatggc ggagatgcga tcggtttgtc gaacttgtgg
    22441 tctcacgggg gcttctttgc aggaggtttc tcaggtttct tctttgcact gtctcttgtc
    22501 attgcagcct atcaaggagt tgagctgatc gggattacag cgggtgaagc gaaggacccg
    22561 caaaacacgc taagaaatgc gattcaaagt attatctggc gtattttgat tttctacatt
    22621 ggtgctattt ttgtgatcgt gacggtgtat ccttgggatg agctcaactc actcggaagt
    22681 ccgtttgtgt ctacgttctc gaaaattgga attacggcag cggccggcat tattaacttt
    22741 gtcgtgatta ctgcggcaat gtccggctgt aacagcggta ttttcagcgc gggccgcatg
    22801 ctgtatacac tgggtgtcaa tggacaagca ccgaaattct ttaagaagat ttcacgcaat
    22861 ggtgtgccgc tgtatggcac aattgcggtg ctgatcggtt tggctgtcgg cgttgtactg
    22921 aactatatcg cgccgccgaa gatctttgtc tatg
//
