LOCUS       c00026_gnlPro..        15645 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPKMGGPE_26.
ACCESSION   c00026_gnlPro..
VERSION     c00026_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:56:35
            Original ID  :: gnl|Prokka|GPKMGGPE_26
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15645
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15645
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2665:5645]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2666..5645
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15645
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15645
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(3..1511)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.9e-48, bitscore:
                     153.5, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSAMKDQLSGIFSGLVSQYVFDIQVAPDHESRQELIDLLGDVA
                     SCSDHLSCSVADGEGLQFTIVKDGMPTGIRFRAVPNGHEFTSLLLAVLNCDGKGKNIPD
                     EGICARVRALNGPIKLTTYVSLTCTNCPDVVQALNVMATLNSCITHETVDGAINQKEVE
                     AMKVQGVPSVFADGRLINVGRSDLGELLSKLEAQYGINEGGVDNSVEKPVKNYDVLIVG
                     GGPAGAASAIYSARKGLNVAVIAERIGGQVKETVGIENLISVPQTTGQQLANDLLTHIN
                     DYPVDILEHRCVDKVELDGSTKLLTTSTGERFSAPALIVATGASWRKLNVPGEADYIGK
                     GVAFCPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEK
                     AKSLPNVEVFLHSQSLEVLGNGDKVTGLRVKDRKTDAERVIDLDGIFVQIGLAANSGVF
                     RDVVETNKPGEIVIDAHCRTNVPGIYAAGDVSTVPYKQIIIAMGE"
     CDS             complement(1516..2082)
                     /locus_tag="ctg26_2"
                     /transl_table=11
                     /translation="MEPIINSQVPEFKVQAFQNGSFKTVSSEDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYGKFQEMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKIAEIHDNGIGRNADELLRKVEAAQFVASHP
                     NEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             complement(2666..3388)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73.4;
                     E-value: 7.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_3"
                     /sec_met_domain="Radical_SAM (E-value: 5.7e-36, bitscore:
                     113.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGRIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWEVKR
                     ETPYLLEPEALLAEVLRYKNFIAKGGVTVTGGEPLLQPEFLKEFFRLCRENGIHTALDT
                     SGYICSGKALEVLEYVDLVLLDIKTIDAGLHPRLTAVKLDNTLRFLDELEKRGIPVWVR
                     HVVVPGLTDNDEDLEKLAGYVSRYKVVQKAELLPYHTMGAYKYEAQGLDYKLKGVEPLS
                     AERLTNAKAIFSKHGITV"
     CDS             complement(3405..5645)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_4"
                     /sec_met_domain="Gly_radical (E-value: 6.9e-46, bitscore:
                     144.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.5e-282, bitscore:
                     927.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENENWAQFKGETWKKEINVRDFIQNNYKPYNGDDTFLVPSSE
                     KTKKVWNKLTEMFKVERKKGVYDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTDEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVPLYGTQILIEEKKRFQKRLDIQELTEEIIQSREEITEQIKAL
                     KAFEKMCAGYGFDVTRPAKDAREAVQFLYLAYLAAVKDQDGAAMSLGRTSTFLDIYIEK
                     DICEGKLTEEEAQELIDQFIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPDNWKNFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQYFGARANLAKCLLYAINGGRDEKSGVQVAPRFEPITS
                     EYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMGLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVKVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVDITEKFM
                     EYLRQHQTYRKATPTQSILTITSNVVYGKKTGTTPDGRPGGTPFAPGANPMNGRDTKGA
                     VAALASVAKLPFQHAHDGISYTFAVSPATLGKERDIQVNNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLLDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINSSL"
     CDS             complement(6072..9119)
                     /locus_tag="ctg26_5"
                     /transl_table=11
                     /translation="MNKKFSTLMAGFLLTSAFASAQILPNNLEPVTFENDKVTSGEYII
                     LRDLTNDGISNDDLALTATLNGSVLTTKAEELSTAKLADAVWKFTVKEETNAAGTKSYT
                     YTLQNKTTGKYLTFDLNGNLTTNASKAGKAEVGTEYSSIFAAVGGTTAANVEFKNDGNG
                     ILYLKGVTVANALALAQTNNVVKVDETGTALILCKYTAEQNADIAKMNDTMGGEGFNLT
                     SAGDKFEGNIFKNGDEYLNLKAFEVVTGTIANVPAGTYFVVVDENMPATLKGKDAQLDK
                     KEEFEAATFVAVDPLKNLNINEVPRGKGKGFWFTKVKGSDFHFNNVAGEVSKKDEIYVG
                     NACFTVINPTLLDETTYQIYTNNARVLKEEGKDDHIAAGKQFIGFVKDQDVDYMITNDE
                     DHALTFKATNETLYDVKGLLNDTDAPAIYTIQFVSGEDKEGVSEYGQWLTVDQHATQSG
                     LRLASVEEINEQDPRFQFVVKKISDYNTDTKKYKKVTFANRQSGVEIELSLFKEGDAYI
                     VYTTDNSNNWDVYPEYIDGNDVNGDVTFGNGVKWATTKIALNPVTVEDKFASFVNREEG
                     AGLVTFALAKNDEAAPEFYVGAKRNAKGLMTGEIFSYSDALDAAQFELEKSEKFLTALN
                     TYMYVKNGRPITSTEKDTVAFYTYKVKAFDADQDNMYLKWGSNNFDLGATGLNFVIKEN
                     IDGSVSLIDYNTTNKLEGNSLKVADKLKDGKTAPWATASAYDLTTLLSEGLKTYMVEES
                     PLVSLEAVPQHISFEAVRGGFMTMDENKDARLAIANEASEDLTFWVDTVHSNLNIPSFY
                     ITKGGNFLYNAVDSASYYAARKNYRFNLENKATGDAKLIFKAGELVSSDTLRTIVDGKS
                     VLVAEKDNAPKKIKGGLKNFQFQIVRAEEGSDEYVIRKDGQYVCQYNNYFYMKADKSEA
                     YRFVIEKQSAPTANEGIATSEVKVIAGEGNVTIAGAAGKKVVISNILGQVVANTVISSD
                     NATIAAPAGVVVVAVEGEAAVKAIVK"
     CDS             9799..10233
                     /locus_tag="ctg26_6"
                     /transl_table=11
                     /translation="MKEKIDSSDIPTSYLLCMKQDCPKATTCLRRIAEQQIGDEVKLWH
                     VISPKYQEKQTDRCAYFRPADKLTYALGFIGMLDRMPYKLMQEAICKLMRRFGRRTYYR
                     VRKGERPLSPDEQKSMLNILKQCGINDPGKFDAYFEAYDW"
     CDS             10822..12162
                     /locus_tag="ctg26_7"
                     /transl_table=11
                     /translation="MKRLTNLLAITLLTSCVTAFAQEQEETTTEKSAVEQSADIYADGY
                     NKFRFGGYGEILANFMDYGINRFRGTDNGSKKDHRNSISIPRFVLAFDYKFNSQWVLGA
                     EIEFEAGGTGSAYEIENTENGEYEMEVEKGGEVALEQFHITRLIHPAFNVRAGHLIVPV
                     GLTNEHHEPINFFGTSRPEGETTILPSTWHENGIEVFGTFGRGYTRFNYQALVVAGLNA
                     NGFDRNTWVAGGKQGLFETDNFTSPGYVARLNYLGVSGLKIGGSFYYCHNTGANSDKPE
                     TYIKYGNIPLRIYTADLQYKNKYVTARANMIYGNLSKADDLSSVNNHQSGGSPYTQTTP
                     IAKRAVSYGGEVGFNLRAVCKDNRNVPVIYPFVRYEYYNPQEKGEGKHTMDLRNKVSMW
                     TAGANWYALPNLVVKADYTTRKIGGGKYNSENEFSLAIAYISWFLSK"
     CDS             12199..13464
                     /locus_tag="ctg26_8"
                     /transl_table=11
                     /translation="MKKKNYFYLAALSLAMTFSMGACSDNNDPNPDGGGKDPVNLDYSS
                     ENASAWGNYMYNVAMLLNDDATMLYNSWVTDYVDEQGSHGPYATIFKDQTAGAYQSPLS
                     CIEEMIESGMWNIANEVGDAKIKDPYTKYTSGDKEGGLYAVESWYSWHSRDDYTNNIFS
                     IRNTYYGRIDDNDVSKVDGNLSAFNSYKDFDDEGDIAEHSLSKMIASTNPDLDEEIKTL
                     IFASAKAIQAIPQPFRNNIDSEESVAAMNTCMELANLLLNEVKPYVNQTFGDPEYDDDL
                     DAIAEQFVDAVVLPTYKDLQEKNKLLLDAVNQFRQNPSNDNFEKACNLWITAREPWEKS
                     EAFLIGPVANLGLDPNMDSWPLDQNGIVQVLNSQNWDDLEWSGNFDEEDEAIGAAQSVR
                     GYHTLEYLLFKDGQPRTVDGAK"
     CDS             13611..15044
                     /locus_tag="ctg26_9"
                     /transl_table=11
                     /translation="MKQSYLLTSSLFLLFACAACEEDDKMDMDKIDVPNGYALSAGTST
                     IFLNSSVAYDTNADWITGANSIRFNNGDGLYDDVRTSNNGDGGGLGPVYAGYSCGSCHR
                     NAGRTKPTLWENGGSGNYGFSSMLVYISRRNGAFFRDYGRVLHDQAIYGVKPEGKLSVT
                     YDKQTFSFPDGETYELCKPNYTITEWYKDSIAPEDLFCTVRIPLRHVGMGQMMAIDRRE
                     IEALAAKSNYPEYGISGRCNYITEKGVTGVGLSGNKAQHLDLTVELGFSSDMGVTNSRY
                     PEEICEGQAQINQGSMMGLSYDQLDISTADMEDVDLYMQSLGVPARRNINDPQVILGEQ
                     KFYEAKCHLCHVTTLHTQAGGSTLLNGTRLPWLGGQTIHPYSDFLLHDMGSEIMGVGLN
                     DNYVSGLARGNEWRTTPLWGIGLQEKVNGHTYFLHDGRARNLTEAIMWHGGEGEASKNL
                     FKQMSKEEREAVIAFLNSL"
ORIGIN
        1 ccttctccca ttgctatgat tatctgtttg tagggtacgg tcgatacgtc gccagccgca
       61 tagatgccgg gaacattcgt ccgacaatgc gcatcgatta caatctcacc cggtttgttc
      121 gtttcgacaa catcgcggaa aacgccactg ttggctgcca agccgatttg gacaaagatt
      181 ccgtccaggt cgatcacccg ctccgcatcc gtcttacggt cttttacacg aagacccgtc
      241 accttatcgc cattaccgag cacttccaaa gattgggaat gcaagaaaac ttccacattc
      301 ggcaagctct ttgctttttc ctgcaacact tggtcggctt tcagttcgtc cataaattcc
      361 agaaccgtca ctttcgaaca aatgcctgcc aaatctatag ccgcttcgat acccgaattt
      421 ccaccgccga caaccgctac gtgcttacct ttatagaacg gaccgtcgca gtgagggcaa
      481 aaagcgacac cttttccgat atagtccgct tcgcccggaa cattcaactt gcgccagctt
      541 gcacctgtcg ccacgataag ggcaggagcg gaaaaacgtt caccggtaga agtggtcaga
      601 agttttgtcg atccatccag ttcgacttta tccacacagc gatgctccag tatatcgacc
      661 ggatagtcgt tgatatgtgt cagaaggtcg ttcgccaact gctgtccggt agtctgagga
      721 acggaaatca ggttctcgat gccgaccgtt tctttgacct gtcctccgat acgttcggct
      781 atcactgcga cattcaagcc tttacgtgcc gagtagatag cagaagctgc accggcaggt
      841 ccacctccca ctattaacac atcatagttc ttaacaggtt tttcaacaga gttatcaaca
      901 cccccttcat taattccgta ttgggcttcg agcttggaaa gcaattctcc caaatcacta
      961 cgccccacat tgatcagcct gccatctgca aaaacagaag ggactccctg tactttcatg
     1021 gcctcaactt ctttttggtt gatagcacca tccaccgttt cgtgagtgat acagctgttg
     1081 agagtagcca tgacattgag tgcctgcacc acatccggac aattggtgca agtaagagac
     1141 acataagtcg tcagcttgat cgggccgttc aaagctctga cacgggcaca gataccttcg
     1201 tccggtatat ttttaccttt tccatcgcaa ttcaggaccg ctaacagcaa agaagtaaat
     1261 tcatgtccgt tgggtactgc acgaaaccgg ataccggtag gcataccgtc ttttacaatt
     1321 gtaaactgaa gtccttcgcc atccgcaacg ctgcatgaca aatgatccga gcatgatgcc
     1381 acatcaccaa gcaggtctat tagctcctga cggctttcgt gatcgggagc gacttgtata
     1441 tcaaatacat attgggatac cagtccggag aaaatacccg aaagctggtc tttcattgct
     1501 gagtctaaca taactttaga tcttaccaac caagtcgatg ctcggcttca aggttgcttc
     1561 gccttttttc cactttgcag gacaaacttc gttcgggtga gaagcaacga actgggcagc
     1621 ttcgacttta cgaagcaatt cgtctgcatt acggccgata ccgttatcgt ggatttcagc
     1681 aatcttgatc ttaccttcgg gatttaccag gaacgtaccg cgataagcca taccctcttc
     1741 ttcaatcatc acaccgaacg cacgacttaa agcccctgtc gggtctgcca gcatcggata
     1801 tttgatctta cggatcgttt cggaagcatc atgccatgct ttgtgtacaa agtgcgagtc
     1861 tgtacttacg gaatatactt cgacacccat ttcctgaaat ttgccgtact tgtcagccat
     1921 atcgaccaat tcggtcggac atacgaacgt aaagtcggca ggatagaaga aaaagatggc
     1981 ccatttgccc ttgatatctt cgctacttac tgtcttgaaa ctaccattct gaaaagcttg
     2041 aactttgaat tcgggtactt gtgaattgat aattggttcc atgattttta ctatttaatt
     2101 tgttactact attttttgtt taccctacaa aggtaaatcg taagatactg attgaaagaa
     2161 tttttcaaat tgataatttt tatctgccga tagacggact tctatcggca agcatactta
     2221 tctactatga caataggaag caaagtaatg ttttccggaa caataaaaat atacctaatt
     2281 gtaggtaaaa tacctttcgg tcataccatg tgattcttta attattacct ttggatgtta
     2341 acttaaaaat attcgaagat gagaagagta gtttgtataa tacattttca acaagtctat
     2401 tgctcgtttt cagtgcatgg ctttcttcat gcgtctcaca aatacccctt acaaaggaaa
     2461 aaccggtaaa caattccact tatcaagtcg aatacctatt cgaacacgaa gggtgtaagg
     2521 tctatcgttt cagggatatg ggacattaca tctatttcac caactgcgag ggagatgtga
     2581 ccagtattga aagcgacagc gtccgcacag tcaaccggat cagccgtaaa ccagtcacca
     2641 tcagagagca gacactcgat taggcttaca cggttatccc gtgtttacta aagatcgctt
     2701 tagcattggt cagacgttct gccgaaagcg gttccacacc tttcagctta taatccaggc
     2761 cctgcgcctc atacttatag gctcccattg tgtgataagg caaaagctcg gctttctgaa
     2821 ccactttata gcgactgacg tatccggcta atttttccag atcctcatca ttatccgtca
     2881 ggccgggaac gaccacatgg cggacccata cgggaatgcc tcgtttctcc agttcatcaa
     2941 gaaaacgcaa ggtgttatca agcttcacag cagtcagacg gggatgaagc ccggcgtcga
     3001 tcgtcttgat gtccaacaaa accaaatcga catattcaag gacttccaat gctttaccgg
     3061 aacagatata gccggaagtg tccaacgccg tatgaatacc gttctcacgg caaaggcgga
     3121 aaaactcttt aaggaattca ggttgtaaca aaggctcgcc accggtcacg gtaacaccac
     3181 ctttagcgat aaaattctta tagcgtagca cttcggcaag caacgcttca ggttccagca
     3241 gataaggcgt ttcacgcttt acctcccaag tatccggatt gtggcaatac agacaacgaa
     3301 gcggacatcc ctgcataaaa acgacaaagc gaattccggg accgtcaacg gtcccgaaac
     3361 tctctaaaga atgtatacgc cccaacatat taatcaatgg acaattataa actgctgttg
     3421 atggtacgcg agatgacgtc gagctgctgt tcgcgtgtca gcttcacgaa gttgacggca
     3481 tagcccgaaa cacggatcgt aagctgcggg tatttctccg gatgttccat cgcatctaac
     3541 agcaagtctt tatcgaatac gttcacattc agatgctggc cgccatcggg cgtgaaataa
     3601 ccatctaaga ggctcactaa gttgttcacc tggatatcgc gttccttacc caacgttgca
     3661 ggagaaacag cgaatgtata ggaaataccg tcatgcgcat gctgaaaagg cagtttggct
     3721 acagaagcca aagcggcgac agcccctttc gtatcgcgtc cgttcatcgg gttagctccc
     3781 ggagcgaacg gcgtaccgcc cggacggccg tcgggagtcg ttccggtttt ctttccgtaa
     3841 accacgtttg atgtgatcgt caggatagat tgtgtcggag ttgccttgcg gtatgtctga
     3901 tgctggcgca gatattccat gaacttctcg gtaatgtcaa cagcaatact gtccgtgcgg
     3961 tcgtcattgt ttccgaaagg tacatattcg ccttcgcgtt cgaagtcgac agccaaacca
     4021 cgttcgtcac ggatcacttt cactttcgta tcacggatgg cagccagcga gtcagcaacg
     4081 atagaaaggc cggcgatacc ggttgcgcgg atacgttcca catctccgtc atgaagcccc
     4141 atctcgaatg cttcatacgc atatttgtcg tgcatgtagt gaatgatctt cagagcattg
     4201 acataaactt ttgccaacca gcgcatcatc tgctcgtatt tctccatcac ttcgttgtag
     4261 tccagatact cgctggtgat cggttcgaaa cggggagcca cctgcacacc cgatttctcg
     4321 tcacgtccgc cattgatcgc atacaacaag cacttggcca ggttggcacg agctccgaaa
     4381 tactgcatct gcttaccgat cttcatcgga gacacacagc aggcgatacc gtaatcgtcg
     4441 ccatagtccg gacgcatcag atcgtcgttc tcgtactgga tggcagaggt atcgatcgat
     4501 acttttgcgc agaagttttt ccagttatcc ggagcattgt tgaaccaaag caccgtcagg
     4561 ttgggttcgg gtgccgggcc gaggttatac aaggtatgca gataacggta agatgtcttt
     4621 gtcaccagcg aacggccgtc aacaccttgt ccgcccagcg attcagtcac ccaaacaggg
     4681 tcgccggaga acaggtcgtt gtattccgga gtacgcagga aacggacaat acgcagtttg
     4741 ataataaact ggtcgatcaa ttcctgtgcc tcttcttccg tcagcttgcc ttcgcaaata
     4801 tctttttcga tatagatatc gaggaaagta gaagtacgtc cgagagacat ggctgctcca
     4861 tcctgatcct ttacggctgc caggtaagcc agatacaaga actgcacggc ttcgcgggca
     4921 tcctttgccg gacgtgtcac atcgaaacca taaccggcac acattttctc aaatgctttc
     4981 agcgctttga tctgctccgt tatctcctca cgactctgaa tgatttcttc tgtcagttcc
     5041 tgtatatcga gacgtttctg gaaacgtttc ttttcttcga tcaggatctg ggttccgtac
     5101 agaggtacac gacggtaatc accgatgata cgtccgcgtc cgtaggcatc aggcaacccg
     5161 gtaatgatgg cggaacgacg tgccgcaatc atctcgtctg tataggctga aaaaacgcct
     5221 tcgttgtgcg tctttctgta tttggtgaag atttcttttg tcatcgggtc cagatgatag
     5281 ccataggctt ccagactgtt ttcgaccatg cggataccgc ctttcgggaa gataccgcgt
     5341 ttcaacgggg cgtctgtctg caagccgacg attacttcgt tttccttatc gatgtaaccg
     5401 ggtccgtatg tgtcaatccc ctggggaagc ttcgtttcgg catcatatac tcctttcttc
     5461 ctttcaacct taaacatctc ggttagtttg ttccacactt tcttcgtttt ctccgaagag
     5521 ggtacgagga acgtatcgtc tccgttataa ggtttgtaat tgttctggat aaagtctctt
     5581 acattgatct cctttttcca ggtttctcct ttgaactgcg cccagttctc gttttcaaac
     5641 ttcataagct tatcttgtct atttcggttt aggcacgcaa agatacgtct tttcccccta
     5701 tctgaaaagg attgtaaagg acgagggatg ttaaaccgga gaaaatacct acaaataggg
     5761 ataagggaaa taaaaacgaa gccccggcag tacgaatacc gccggggcct gttttttgtc
     5821 tgccgtccgg tcttcacaga gggaaaagca gtagaacttt taatttcatt actttagtat
     5881 tattaatatt aaatccaacc gcttgttcgc ctgtcgcagg gtaattgaaa ccatagatca
     5941 agaaaacctc ttacatacgg tttcacgcag gttgtctaga attatttgat tataaaatgt
     6001 cattgtgcct gtgtaagggt ggttcgctaa ccacccttac gatagacagt attgtttttt
     6061 agtatcaatc gttacttaac gatagctttt acagcagctt caccttcaac agctacaact
     6121 actacacctg ccggagcagc gattgttgcg ttgtcagaag agattactgt gttagctact
     6181 acctggccta agatgttgct gataacaact ttcttaccgg cagcgcctgc gattgttacg
     6241 ttaccttcgc cagcgatcac tttcacttca gatgttgcga tgccttcgtt ggctgtagga
     6301 gcagactgtt tttcgatgac gaagcgataa gcttcagact tgtcagcctt catgtagaag
     6361 tagttgttgt actggcatac atactggcca tctttacgga tcacatattc gtcactacct
     6421 tcttcggcac gtacgatctg gaactggaag ttcttcaaac cacccttgat cttcttcgga
     6481 gcattatctt tttctgcaac caaaacagac ttgccgtcaa cgatagtacg caaagtatcg
     6541 gaagaaacca attcacctgc tttgaagatc aacttggcat cacctgtcgc tttgttttcc
     6601 aagttaaagc gatagttctt gcgagcagcg tagtagcttg cagagtctac ggcattgtac
     6661 aagaagtttc cacccttcgt gatatagaat gacgggatgt tcaagttcga atgaaccgtg
     6721 tcaacccaga atgtcaagtc ttcgcttgct tcattggcaa tagccaggcg agcatctttg
     6781 ttttcatcca ttgtcatgaa acctccacga acagcttcga aagatatatg ctgcggaaca
     6841 gcttccaaac ttactaacgg agattcttct accatgtaag tcttcagacc ttcgctaagc
     6901 agagttgtca agtcgtaagc cgaagcagta gcccaaggag cagtcttgcc atctttcaat
     6961 ttatcggcaa ccttcaagct attaccttcg agtttattag tagtgttata atcaatcaag
     7021 ctaacagaac catcaatatt ttctttgata acgaaattca aaccagttgc acctaaatcg
     7081 aagttgttag aaccccattt caaatacata ttgtcttgat cagcatcaaa ggctttaacc
     7141 ttatatgtat agaaagcaac cgtgtccttt tctgtagaag tgataggacg gccgttcttc
     7201 acatacatat atgtattcag agcagtcaag aacttctcgc tcttttccaa ttcgaactga
     7261 gcagcgtcca aagcatcact ataagagaat atttcaccgg tcatcaaacc tttagcattt
     7321 ctcttggcac ccacatagaa ttcaggagca gcttcatcgt tcttagccaa ggcgaatgtc
     7381 accagacctg caccttcttc acggtttacg aaagaagcaa acttgtcttc tacagttacc
     7441 ggattcaacg caatcttggt tgtagcccat ttaacaccat taccgaatgt aacgtctccg
     7501 tttacatcat taccatcaat atattcagga taaacatccc agttattgct attatcagtc
     7561 gtatatacaa tgtaagcatc accttctttg aacaaagaca attcaatttc aacaccagac
     7621 tgacggtttg caaacgttac ctttttgtat tttttggtat ccgtgttgta atcgctaatc
     7681 tttttaacaa caaactggaa gcgcggatcc tgttcattga tttcttctac cgaagcgaga
     7741 cggagaccac tctgggttgc atgttggtca actgtcaacc actggccata ctcgcttacc
     7801 ccttctttgt cttcaccgct gacgaactgg attgtgtaga tagccggagc atccgtatcg
     7861 ttcaacagac ccttaacatc ataaagtgtt tcgtttgtag ccttgaatgt aagggcatga
     7921 tcttcatcat tcgtgatcat gtaatctaca tcctggtctt ttacaaaacc gatgaactgt
     7981 ttaccggcag caatatggtc atccttacct tcttctttca aaacgcgagc gttgttagta
     8041 taaatctgat aagttgtttc gtccaacaaa gtcgggttga tcactgtgaa acaagcgtta
     8101 cccacataga tttcatcctt cttagaaact tctcctgcca cattgttaaa atggaagtca
     8161 gagcccttta cctttgtaaa ccagaaccct ttacctttac cacgcggtac ttcgttgatg
     8221 ttcaggtttt tcaacggatc aacagctacg aatgtagcag cttcgaattc ttctttcttg
     8281 tccaattggg catctttgcc tttcaatgta gccggcatgt tttcgtctac aacaacaaag
     8341 tatgtaccgg cagggacatt agcaatagtt cctgttacaa cttcgaacgc cttcaaattc
     8401 agatattcat caccgttctt gaagatgttg ccttcaaact tgtcaccggc agatgtcaga
     8461 ttgaagcctt cgccacccat tgtgtcgttc atcttggcga tgtcggcatt ctgttctgca
     8521 gtgtatttgc aaaggataag agcggtacca gtttcatcta ccttaaccac attgtttgtc
     8581 tgggccaatg ctaacgcatt tgcaaccgtc acccctttca gatacaagat tccgtttcca
     8641 tcgtttttga actcaacatt tgcagctgtc gtaccgccta cagcggcaaa gatagagctg
     8701 tattctgttc caacctcagc tttgccagct tttgacgcat tggtagtcaa atttccgtta
     8761 agatcgaaag tcagatactt gccagtcgtt ttgttttgta aggtataagt gtacgacttt
     8821 gtaccagcag catttgtttc ttcctttaca gtgaatttcc aaacagcatc tgccaacttc
     8881 gcagtagaaa gctcttctgc tttagtagtc aatacgctac catttaaagt agctgtcaaa
     8941 gccaagtcat cattacttat cccatcattc gtcaagtcac gaaggataat gtactcgcct
     9001 gaagtcactt tgtcattttc aaacgttacc ggctccaaat tattgggcaa aatttgcgca
     9061 gaagcgaacg cacttgtcag caggaaccct gccattagag tagaaaactt cttgttcata
     9121 atctaaaatg tttaattaat aataatatgt atattgaata tcgttcttac ttcctgttta
     9181 acaggttttt accaaattcc tgtattttga cgagataaaa cgtacgtttt ttttagtcat
     9241 ttttgagggg ctttcgggag ggtttgtgtt ggaaagctgg tttttcgtac ttgttaagct
     9301 atctgattga taagaaagaa tatagaaaag gaaaaataat tggaagaaag gattgcaggt
     9361 tcaaaaagta gttgtatttt tgtgcagtga aaatggcgaa agaaaacgta cgttttttcg
     9421 ctatttttct tcttataccc atatacttct tattagcaat gacttacatt gcaaaaagtg
     9481 cctaaagcca tataaaaaaa gagctgtttt caaccgctcg ccaaacttct ttacatcttc
     9541 atcaaaacaa agataatcaa tcacctataa gattaacttc ctttatttac attggagggg
     9601 aaaaacagca aaaacagcag gtttcgtaat ttcatcttgg aaaagctccc ccttctgtta
     9661 aagatataca aaatacggag tattggttgc ttagctcaat aacagcttca agacttgcaa
     9721 aaccttacat tattatgtat ctttacatca acgtccgtca cagacggatc aaacaactat
     9781 aatacgttaa tacaatatat gaaagaaaaa atcgactctt ccgacatccc cacctcctat
     9841 ctgctctgca tgaaacaaga ttgccccaaa gccactactt gcttgaggag aatcgcagaa
     9901 caacagatcg gcgacgaagt caaactgtgg cacgtcatca gccctaaata ccaagagaag
     9961 caaaccgacc gatgtgctta tttccgccct gccgataaac tgacctatgc gctcggtttc
    10021 atcgggatgc tggaccggat gccctacaaa ctgatgcagg aagccatttg caagctgatg
    10081 agacggttcg gacgcaggac ttactaccgc gtgcgaaaag gcgaacgccc gctctcgccg
    10141 gacgaacaaa aaagcatgtt gaacatactg aaacagtgcg gtatcaacga tcccggaaag
    10201 ttcgatgcct acttcgaggc atacgactgg taagttcaca tgacgcaact tgcctacgta
    10261 ttggttgtgc catacctatg taacgaccgt ttcctcggca tgaaacggtt gtgccaagct
    10321 tatgtaacag gcgtttccta ctcaggaaac agttgtgcca agccgatgta attgttttgg
    10381 cacagccgga gcagcaaaca gacccttgcg ggaacaagtc caagactcga cgccgaacag
    10441 attccggaca gaagcgaatg ggaaacggaa acataaaaaa gaagcctctc ttcacagaga
    10501 ggcttctttt ttataccgaa aataaccaat aaaaactttt cgatatagtt aatcatctta
    10561 tatgcttaca taattgacaa aaggttttga tatagcgatt atactaatag tgttactttc
    10621 ttaatgacat tgcaaagata cgggtacttc ccacctccta caatacctat atgtgagtaa
    10681 aaaaacgtct tttactacct aatcaaggtg atattcaggc gcaataccta caaatgggta
    10741 acatcggaac ctttttacct actaattgcg attgcacacc gttgacagcc cctctaattt
    10801 tgccaaaaat taaaaaacgc aatgaaaagg ttaactaatt tattagcaat cactctactc
    10861 acctcttgtg taacggcatt tgcacaggaa caagaagaaa caacgacaga aaaatccgca
    10921 gtggaacaat ccgcagacat ttatgccgac ggatataaca agttccgctt cggcggatat
    10981 ggggagatcc tcgcaaactt tatggactac ggcatcaacc gtttccgggg tacggacaac
    11041 ggaagcaaga aagatcatcg caattcgatc tccatacccc gttttgtctt ggctttcgat
    11101 tacaaattca attcccaatg ggtattagga gcagaaatag aatttgaggc tggaggtacg
    11161 ggaagtgcct atgagataga aaacacagaa aacggagaat acgaaatgga agttgaaaaa
    11221 ggcggtgaag ttgctttgga acaattccac atcacacgtc ttatccatcc ggccttcaat
    11281 gtccgtgccg gtcatttgat cgtcccggtc ggtttgacca acgagcatca cgagccgatc
    11341 aacttcttcg gaacttctcg tccggaaggc gaaacgacca tccttccttc tacctggcac
    11401 gaaaacggta tcgaagtgtt cggtacgttc ggccgaggct acacacgttt caactaccag
    11461 gctttggtcg ttgccggatt gaacgccaac gggttcgacc gcaatacatg ggttgccggc
    11521 ggcaagcagg gactattcga aacagataac ttcacctcac cgggctatgt ggcccgcctg
    11581 aactatttag gagtatcggg attgaaaata ggcggttcct tctactattg ccacaatacg
    11641 ggagccaatt ccgacaaacc ggaaacatac atcaaatatg gaaacatacc tttgcgtatc
    11701 tatacggccg acctgcaata caaaaacaaa tatgtcaccg cacgcgcaaa catgatatac
    11761 ggcaacctga gcaaagccga cgacctcagc agtgtcaaca accaccaaag cggcggttct
    11821 ccttatacac agacaacccc gatcgccaaa cgtgcggtca gctatggtgg cgaagtgggg
    11881 ttcaacctgc gtgcggtttg taaagacaac aggaacgtgc ccgtcatcta tccgttcgtc
    11941 cgctacgaat actacaaccc gcaggagaaa ggcgaaggca agcacacgat ggacttacgc
    12001 aacaaagtaa gcatgtggac agccggagcc aattggtatg ctttacctaa tcttgtcgtg
    12061 aaagcagact atacaacacg caaaatcgga ggcggcaaat ataacagcga aaacgaattc
    12121 agcttggcca tcgcctacat cagctggttc ctcagcaaat aaaaacaaca taaacaattt
    12181 aatagcttaa tcaataaaat gaaaaagaaa aattatttct atctggcagc cttatcgctc
    12241 gccatgacat tctcgatggg agcatgtagc gacaacaacg accccaatcc ggatggtggc
    12301 ggaaaagatc cggtcaacct ggattacagt tctgaaaacg ccagtgcatg gggtaactat
    12361 atgtataacg ttgcaatgtt gctgaacgac gatgcaacca tgctctacaa ttcttgggta
    12421 accgactacg tcgatgagca gggttcacac ggcccatatg ccacgatctt caaagaccag
    12481 actgccgggg cttaccaaag tccgctctcg tgtatcgagg aaatgatcga aagcggtatg
    12541 tggaacatcg ccaacgaggt gggcgacgcc aagatcaaag acccgtatac caaatatacc
    12601 agtggtgaca aagaaggcgg tctttatgcc gtcgaatcat ggtatagctg gcattcgcgc
    12661 gacgactata cgaacaatat cttctccatc cgtaacacat attacggccg tatcgacgac
    12721 aacgacgtgt ccaaagtaga cggaaacctg agtgcattca actcttacaa agatttcgac
    12781 gatgaaggag acatcgcaga acactcgctt tcaaaaatga tcgcttcaac caacccggat
    12841 ctcgacgaag aaatcaaaac gctgattttc gcttctgcaa aggcgattca ggctattcca
    12901 caaccgttcc gcaacaacat cgacagcgaa gagtccgttg ccgcaatgaa cacttgcatg
    12961 gaactggcca acctgttgtt aaatgaagta aaaccgtatg taaaccaaac attcggcgat
    13021 cctgaatacg acgatgacct tgatgcaata gccgaacagt ttgtcgatgc ggtcgttctt
    13081 cctacttata aagacttgca ggaaaagaac aagcttttgc tggatgcggt aaaccagttc
    13141 agacagaacc caagcaacga caacttcgaa aaggcctgca acttatggat cacggcacgc
    13201 gaaccgtggg aaaagagcga agctttcctt atcggcccgg ttgccaactt aggtttggac
    13261 cccaacatgg acagctggcc tttggaccag aacggcattg tacaggtatt gaactcacag
    13321 aactgggatg acctggaatg gagcggaaac tttgacgaag aagatgaagc catcggagcc
    13381 gcacagagcg tacgtggtta ccatacattg gaatatctcc tgttcaaaga cgggcagccc
    13441 cgcactgtcg atggagcaaa ataaacatgc ctctgagaca taaaactaga taatagatca
    13501 tgacaaacct tgaaacagca gacaaatgcc cgctgtttca gggtttcaga gttattacac
    13561 aatgcgactc gcgttattcg gaaataaatt cagaaaacca ataaaatgat atgaagcaat
    13621 cttacctgtt aacatcctcg ctattcctgc tctttgcatg cgcagcttgt gaagaggacg
    13681 ataaaatgga tatggataaa atagatgtcc cgaacggata tgcgctgtca gcagggactt
    13741 caacgatttt cctaaactca tcggtcgcct acgatacgaa cgccgactgg ataacaggag
    13801 ccaactcgat ccgtttcaac aacggcgacg gtctctacga cgatgtacgc accagcaaca
    13861 atggcgacgg aggcggtctc ggacctgttt atgccggcta ttcctgcggc agttgccatc
    13921 gcaacgcagg aaggaccaaa ccgacattgt gggaaaatgg cggatcgggc aactacggtt
    13981 tctcttccat gctggtctat atctcccgcc gcaacggtgc tttcttccgc gactacggac
    14041 gtgtattgca cgaccaagcc atctacggcg tcaaaccgga aggtaagttg tccgtcacat
    14101 acgacaagca gactttttcc ttccccgacg gagagactta cgaactatgc aaacccaatt
    14161 acacgataac cgaatggtat aaagacagta tcgccccgga agatttgttc tgcaccgtac
    14221 gcatcccgtt acgccacgtc ggtatgggac agatgatggc aatcgaccgc agggaaatcg
    14281 aagcgctcgc tgccaaaagc aattatccgg aatatggtat cagcggacgt tgcaactata
    14341 tcaccgagaa gggtgtcacc ggtgtcggcc tttcaggaaa caaggcacag catcttgacc
    14401 tgaccgtcga actgggcttt tcaagcgata tgggcgtgac aaacagccgc tatccggaag
    14461 agatttgcga agggcaggct cagatcaacc aaggcagcat gatgggactc tcgtacgacc
    14521 agctcgacat atcgaccgcc gatatggaag atgtggacct ttacatgcaa agcctcggcg
    14581 taccggcacg gcgcaacata aacgaccctc aggtcatctt aggagaacaa aagttttacg
    14641 aagcgaaatg ccatctctgc cacgtcacta cgctgcacac gcaagcgggc ggttccacac
    14701 tgctcaacgg cacacgtttg ccatggctcg gcggacagac catacatcct tattctgatt
    14761 tcctactgca tgacatgggg tcggagatca tgggagtcgg gttgaacgac aattatgtca
    14821 gcggcctggc acgaggaaac gaatggcgta ctacgccgct ttggggtatc gggctgcagg
    14881 agaaagtcaa cggtcatacc tatttccttc atgacggacg cgcccgcaac ctgaccgaag
    14941 ccatcatgtg gcatggaggc gaaggggaag cctccaaaaa tttattcaaa caaatgagca
    15001 aggaagagcg tgaggcagtg atcgcattcc tcaactcctt ataatttatc cataagacaa
    15061 actaaaatga aacaactgat aatcacaatt gcagcattat tactattgcc gttggccgtc
    15121 atggcccaat atgaggaaga tacggaaaac ggtgtcgtat cactaaacgg caaagaaggt
    15181 tttacaatcg ctaccaagaa gggggatttc gttttcaaac cttatatgtt ggtacagacc
    15241 agtgctaaca tcaactacta cgacgatgaa ggactggacc cagcctacaa tcaagataat
    15301 atacacaaca gcggtttctc gattccctat gccatcctcg gtttcacggg caaggcattc
    15361 gaccgggtga cattcaacct ctccatcaat gctgccggaa acggaggaaa catccttcaa
    15421 caggcttggt tcgacgtaga gataaaaaag agttttgcca tacgtgtcgg caagttcaag
    15481 actccgttct cgcacgctta cctgactacg ctgggcgaga cgttaatgcc gacactgccg
    15541 acatcgctca cctcatccgt gatcctgcct tattctctta atgccgtgac accgaacatc
    15601 ggcatgggat tcgacctcgg agtggaagtg cacggattgg taaag
//
