LOCUS       c00030_gnlPro..        14751 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PNKDKHOP_30.
ACCESSION   c00030_gnlPro..
VERSION     c00030_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:59:52
            Original ID  :: gnl|Prokka|PNKDKHOP_30
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 36967
            Orig. end    :: 51718
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14751
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[46967:51179](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..14212)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14751
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14751
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             777..1787
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_39"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1e-08, bitscore:
                     27.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIIVVSNSLSKRIEYFIEAGKHLQVEVRFMTYGELFNCLPQLRQ
                     AVIKLEPCVSDETNFLKYALLNQAYKETLQRLGEMRLSDDVCFLNTPHALLRALDKKET
                     KQVLMDRGLKVTPMLPSPRSFDELRELLADCGRGCFLKPRYGSGAGGIMAVRYQPNRNK
                     WVVYTTLQQVDGVIHNTKRINRLSTEKEMIPLAEAVMQTEAILEEWIPKEQLQGENYDL
                     RVVCRESEIDYIVVRCSKGSITNLHLNNKAHWWNELSLPEVVRQQIYFQCQEAVQSLDL
                     QYAGVDVLIERGTDIPYIIEVNGQGDHVYQDMFAHNSIYIQQIKNIKKRYNHANR"
     CDS             1774..2628
                     /locus_tag="ctg30_40"
                     /transl_table=11
                     /translation="MQIDELPAGEQTQNPDLDMNQVVGTHDILMLCFDTLRYDVSKEEE
                     EAGRTPVLNSHGGEWEKRHAPGNFTYPSHFAIFAGFLPSPAEPHSLRSRKWLFFPVQAG
                     TGRIPPAGSYPFTEATFVQSLANVGYETICIGGVNFFSKRNELGRVFPGYFTKSYWLPT
                     FGCTAPDSTEKQIDFALKKLENYPEDKRIFMYINFSAIHYPNCHYVEGKMKDDKESHAA
                     ALQYVDSQLPRLFQAFQKRGNTLVIALSDHGTCYGEDGYEYHCISHETVYTVPYKHFIL
                     TKK"
     CDS             2625..3902
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_41"
                     /sec_met_domain="Radical_SAM (E-value: 3.2e-16, bitscore:
                     51.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQPLPRYVDYMYSYPHKTAYRSFPSPVSLVPYLKQVEGQKASLY
                     FHIPFCSHKCGYCNLFSLQTNRADYIATYLETLHKQAQQLSPLTTGLAFDSFAIGGGTP
                     LLLTVPQLEYLLDTAALFGVHPSHTFTSVETSPEYADPTRLDLLKQAGVARVSIGVQSF
                     LDEELTALKRRPRRDMINQALEAIRKRQFPFFNIDLIYGIRGQTVASFLYSLEQALLFQ
                     PNELFIYPLYVRPGTAITERESDDVCFQMYCAACDLLKDRGFLQTSMRRFIHHPSTDAE
                     ISCGDEVMLSCGSGGRSYLGNLHYATRYTVCQRCIAGEIDDYMGTTDFTVARNGFILSQ
                     EERRQRFIIKNLMYYMGLDKAEYKRRFGESPDNVMLFRQLAERQWIENTDNGRICLTSD
                     GMAYSDYIGQLFITPEIRELMETYSY"
     CDS             3914..5479
                     /locus_tag="ctg30_42"
                     /transl_table=11
                     /translation="MENESSLLSFRHIYYRGKLNSCNYTCSYCPFGKKSHLADTTQDEQ
                     AWNRFIAAIEQWKGEPLQLFIIPYGEVLIHRYYRKGMVHLAALPQVAGISCQTNLSFPA
                     KHWLDEIRVAPTVISKIRLWASFHPEMTSVEKFAHQIHILHHAGIQVCVGAVGNPSAKA
                     VLNDLRNALLPDIYLFINAMQGLRAPLSQEDIQFFSQLDNLFEYDLKNAPVQWEVCAGG
                     RDNCFIDWKGDMYACPRSRVKIGNFYQGDGAVVPLSCKRKVCDCYIAFSNLNNHPLHRI
                     MGEGAFWRIPDKPLITTVFFDVDGTLTDSQGKVPESYANALRYMAQSVSLYLATSLSME
                     QAKKKLGKALFDLFRGGVFADGGLLSYSRQIKCLPVKVYPEVYGESSKVTIHSYEGVVY
                     KYSILVRDKEQRESILTRLKENPCQVFHKAPLITVIHPEASKKEGMLQLCKALGLASEH
                     TLVVGNSLKDWPMMSVVSHSCAVMNAEPLLKECARYTLNPDRLAAFFRFSNGDPIDQTS
                     SDNS"
     CDS             5716..7080
                     /locus_tag="ctg30_43"
                     /transl_table=11
                     /translation="MKELDLTQGSVPKVLLQFAVPFLIANVLQALYGGADLFVVGQYDD
                     SASVAAVAIGSQVMQTITGIILGITTGTTVLIAIATGAKDNRKVAFTIGSSVWLFSITG
                     VVLTLVMVLFHSRIAELMHTPVEAMVDTKNYILVCSLGILFIVGYNVVCGILRGLGDSK
                     TPLYFVGLACVINIVLDFILVGYFHWGATGAAIATVTAQGVSFGIALWFLYRHGFHFDF
                     SRKDIRLNRNLSKKILVLGAPIALQDALINVSFLIITVIVNQMGVIASASLGVVEKIIV
                     FAMLPPMAISSAVATMTAQNYGAGLIKRMNKCLASGIGIALVFGVSVCVYSQFLPETLT
                     AFFTKDAAVVAMAADYLRGYSIDCIVVSFVFCINSYFSGQGNSLFPMIHSLIATFLFRI
                     PLSYWFSQIDSSSLFIMGFAPPISTVVSLLICIWYLRYTQRKLYLRGTMMPAMSN"
     CDS             7121..7669
                     /locus_tag="ctg30_44"
                     /transl_table=11
                     /translation="MEAYLKKLCFEYQVDEREVKELLARMEMVYLDKGETIASATLPEQ
                     SLYIIVSGILHTYTTHEGEERTNRFFSAGDAVLCYNSSQYSIKTLTKCAAYYISEEEIE
                     ELCASSISFANLVRQLMEYQFYFKEEEDMNARKLTVRERYLSLLAEIPDILYRVPLKHI
                     NHYLGADVTSLGYLAGSSK"
     CDS             7793..8671
                     /locus_tag="ctg30_45"
                     /transl_table=11
                     /translation="MKNSIPRYTFYKHKYGSELLVDVVELKYVKKFLAKSAVHTLNYYD
                     ITFITEGKGAFSVDNQTYEAIPRDVLFSKPGEIRNWDTHHITNGYALIFEEEFLSFLFK
                     DSLFVQHLSFFQIESSSSLLHLSDELYTRILETLHDIKMEIDSYQQGDVHVLRALLYEV
                     LMLLDRAYLKMTSIEEGRSREVSNNHVSKFMNLVATHAKEQHSVQYYADKLCITPNYLN
                     EMITSTMGISAKQYIQSKVMEEAKRLLVYTDFPIADIAFELCFSTVSYFIRSFRQHTGE
                     TPLLYRKVHKP"
     CDS             8764..9186
                     /locus_tag="ctg30_46"
                     /transl_table=11
                     /translation="MMRDAEKTVGNMIDKLKTAFIGSIDGEGFPTIKAMLQPRKRKGIK
                     TIYLTTNTSSMRVAQYRENNHACIYFCDTRFFRGVMLRGTMDVLTDSASKEMIWQEGDT
                     MYYPEGVTDPDYCVLKFTAISGRFYSNFKSEDFVVE"
     CDS             complement(9376..9996)
                     /locus_tag="ctg30_47"
                     /transl_table=11
                     /translation="MATTEHSDLEQQIIKTAQQLFIEKGFVETSMSDIAATVGINRPTL
                     HYYFRTKDKMFKAVFGSIVMSLMPKIQDIVKQDIPFMERLSMILDEYIELFTSNPCLPR
                     FICGEIQRDVNHLLATAKELQFGDALSQVKDSILTAMEDGKLKKVPIHIVFLTVYSLLS
                     YPFLAKNLIVSLFLEDEAAFADFLQEWKQNIINQLQNLLCYEE"
     CDS             complement(10001..14212)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_48"
                     /sec_met_domain="HGD-D (E-value: 2e-22, bitscore: 72.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.5e-33, bitscore:
                     108.0, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVYKVGLDIGSTTTKMVVLDKDGTTVLFSGYKRHQAKIQECLLG
                     FLYQIKEQLGDIPLSFHITGSVGMGISEKCSLPFVQEVVAATNYVCREHPHTATMIDIG
                     GEDAKVVFFQDGQATDLRMNGNCAGGTGAFIDQMAILLGVSIDELNELALRSNQVYSIA
                     SRCGVFCKTDIQNLIAKNISKENIAASIFHAVAVQTTVTLARGCNIVAPVLLCGGPLTF
                     IPALRKAFANYLNLSQDTDFILPEKGNLIPAWGAALAENNEESIHLSNLIQVIENKLSV
                     TSPFQSDLSPIFDSEEEYRSWKKEKDQYKIQYASLRPGLQEATIGIDSGSTTTKIVVLD
                     NNHRILYSYYHDNNGNPIKTVENGLQKLYEECRRRGTTLRIKGGCSTGYGEDLIKAAFH
                     MDAGIIETIAHYAAAKHISKEVSFILDIGGQDMKAIFVNDGVINRIEINEACSSGCGSF
                     ISTFAQSLDYSVEDFAKAACFSQAPCDLGTRCTVFMNSKVKQVLREGASVADIAAGLSY
                     SVVKNCLYKVLQLKDTEILGDHIVVQGGTMRNDSIVRSLEKLTGKQTFRSNCPELMGAL
                     GCALYAKQIENARVTELNEMLQWAQYTSKQLQCRGCENQCAIMRYTFNNDNHYFSGNRC
                     EKVFSNKGSHADKGINTYDKKLELLFDRSADIPQPLFTIGIPRILNMYEEYPFWHTLFT
                     ACGIQVQLSAPSTFSKYETAAGMVMSDNICFPAKLVHSHIRNLTLQNVNRIFMPFVVFE
                     KKDKQQQNSYNCPIVSGYSEVIKSVQEENIPIDAPTITFKDEALLYKQCYEYLKSLGIR
                     DEVCKNAFSRALQEQYAFEEKIAAYNQEVLNEGREKHKLIILLAGRPYHSDPLIQHKVS
                     DMIAAMGVYVITDDIVRQQEISLEKTHYLSQWAFTNRILKATKWAAMQEGDIQYMQMTS
                     FGCGPDAFLIDEVRNLLKRYGKNLTLLKIDDVNNIGSIKLRVRSLVESLNFSLKHSQAK
                     DPEPFVSTAPFTKKDKKKKILAPFFTPFISPLIPSIMKVAGYEMETLPLSDTASCDWGL
                     KYSNNEVCYPATLIVGDIVKAFKSGRYDPANTCVAITQTGGQCRASNYISLIKKALIEN
                     GYTNTPVVSLAFGSGIENEQSGFKVNWLKVLPIILASVLYSDCIAKFYYAAVVREKERG
                     QAARLRDLYLDTAQPIIQKNKPEDLLSYLYLAARDFNKICEQRSCHKVGIVGEIFLKFN
                     PFAQKDVTSWLINQKIEVIPPLISDFFMQGFVNLKVRQNQHLQRKLTPDFVIDWLYKKV
                     QKQINKVNEIGKNFNYFTPFESIFEKAEKAKQVISPGTQFGEGWLISGEILSFASQGVN
                     HVISLQPFGCIANHIVEKGIEKRIKSLCPQMNILSLDFDSSVSDVNITNRLLLFIDNIN
                     N"
ORIGIN
        1 tgaaagataa acatctctct gaatataaac aaataacaat cggttgttgg gattatgagg
       61 gtggcgactg ttctgcctta ttacagggaa tgattgaaaa taaggagaag ttcgcacaaa
      121 tagaaggctt gttctgggga gatattgagc aggaagaaca ggagatttca tggattgaac
      181 aagctgatat tagtccgctg ctcgatgcca tgcctaaatt gaaagatctg aaaatcaaag
      241 gaaccaataa tctgcgtttg ggaaagactt cacggccgga gttgcggtca ctcgaaatta
      301 tcagtggtgg cctgcctacc gaagtggtag aagatattct tggttctgat ttccccaatc
      361 tggaaaaact gattctatat gttggtgtgg aagattatgg atttgaagct gatattgaga
      421 tattccgtcc gttgttctcc aaagaacgtt tcccgaagct gacttatctg gggatcgtca
      481 actctgaaga acaggacaag attgtagaaa tgttcctgga gtcggatatt cttccccaac
      541 ttgaaacaat ggatgtttcg gctggtactc tcaaagatga aggtgcccaa ttattgctgg
      601 ataatatgga taagatcgct catttgaagt ttatcaatat gcgctataat tatttgagca
      661 aggagatgaa gaaacagttg cagagtctcc ctatgaaaat agatattgct gaaactgaag
      721 aggcagatga atatgatggt gaattgtggt attacccgat gattacagaa taggagatgc
      781 agataatcgt tgtcagcaac tctctgtcca aacgtataga atactttatt gaagcaggca
      841 aacacttgca ggtggaagtt cgttttatga cttacgggga actttttaac tgcttgccgc
      901 aactacggca ggcagttatc aaactggaac cttgtgtaag cgatgaaacg aatttcctga
      961 aatatgcgct gttgaatcag gcatataagg agacactgca acgtttaggc gagatgaggc
     1021 tatctgatga cgtgtgcttt ttgaatactc cccatgcttt attacgtgct cttgataaaa
     1081 aggaaactaa acaagtgttg atggacagag ggttgaaagt gactccgatg ttaccttctc
     1141 cccgttcttt tgatgagttg agagagcttc ttgccgattg cggtagagga tgctttttga
     1201 aaccccgtta cggttcgggg gcgggaggta ttatggctgt tcgctatcaa cccaaccgga
     1261 ataaatgggt agtctatact accttgcaac aagtggatgg agtcattcat aacactaaac
     1321 gtatcaaccg tttgagtacg gaaaaagaga tgatcccgtt ggcggaagct gtgatgcaaa
     1381 cagaagctat tttagaagaa tggattccta aagagcagtt gcagggagag aattatgatc
     1441 ttcgtgtagt gtgccgggaa tctgaaattg attatatcgt tgtgagatgc agtaaaggaa
     1501 gcataaccaa tctgcatctg aacaataagg cacattggtg gaacgaattg tctttgccgg
     1561 aagtagtgcg gcaacaaatc tattttcagt gtcaggaagc ggttcaatct ttggatttgc
     1621 aatatgccgg agtggatgta ctgatagaga gaggaacaga tattccttat ataatagaag
     1681 tcaacggaca gggagatcat gtgtatcagg atatgtttgc tcataattct atttatattc
     1741 aacagataaa aaacataaaa aagagatata accatgcaaa tagatgaact gccggctggc
     1801 gaacagaccc aaaatccgga tctggatatg aatcaggtgg tgggtactca tgatatattg
     1861 atgctttgct ttgatacctt gcgttatgat gtcagcaagg aggaagaaga ggcaggaaga
     1921 acaccggtac tgaacagtca cggaggagaa tgggaaaaaa gacatgcgcc gggaaatttt
     1981 acttacccgt ctcattttgc catctttgca ggatttctgc cttctccggc ggaacctcat
     2041 tcgctacgca gccgtaagtg gttgtttttc cctgtgcaag ctggtacggg acgtattccg
     2101 cctgcgggaa gttatccgtt tacggaagca acttttgtgc aaagccttgc caatgtaggc
     2161 tatgaaacga tttgtatagg aggggtgaac ttcttcagca agcgtaatga actggggcgt
     2221 gtgtttcccg gttactttac taaaagttat tggctgccga cctttggatg cacggcaccc
     2281 gatagtactg aaaaacaaat tgattttgca ttgaagaaac tcgaaaacta tccggaggac
     2341 aaacggattt ttatgtatat caatttttct gctattcatt atccgaactg tcattatgtg
     2401 gaaggcaaaa tgaaggatga taaggaatca cacgctgccg cgctgcaata tgtcgacagt
     2461 cagctacccc gtttatttca ggcctttcag aagcggggaa atacgctggt gattgctctt
     2521 tccgatcatg gcacttgcta tggagaggat ggatatgaat atcattgcat atctcacgaa
     2581 acggtttata cagtccctta caaacacttt attttaacga aaaaatgaat caaccgctac
     2641 cacgatatgt agactatatg tatagttatc cacataaaac tgcttatcgt tcttttccgt
     2701 ccccggtttc gctggttcct tacctgaaac aggtggaagg acagaaagca tcgctttatt
     2761 tccatattcc tttttgtagt cataaatgtg gatattgcaa cctgttttct ctgcaaacaa
     2821 atcgtgcgga ttatatcgca acttatttgg aaactcttca caagcaggcg caacagttgt
     2881 ctccactcac taccggactg gcatttgata gtttcgccat tggaggaggc acaccgttgc
     2941 tcctcactgt tcctcaactg gaatacctat tggatacggc tgccttattc ggagtgcatc
     3001 cttcacatac ctttacttcc gtagaaacat cgccggaata tgccgatcct acccgtttgg
     3061 acttgttgaa gcaagcagga gtagctcgtg tgagtattgg cgtacagagt ttccttgacg
     3121 aagaattaac agctttgaaa agacgtcccc ggcgagacat gattaatcag gcgctggagg
     3181 ctattcggaa gagacaattc ccgtttttta atattgattt gatttacgga atcagaggac
     3241 aaactgtggc cagctttctt tattcattgg aacaggctct tctgtttcag cctaacgaac
     3301 tctttatcta tccgctatat gtacgaccgg gaacggctat cacggagcgg gaatccgacg
     3361 atgtctgttt tcagatgtat tgtgccgctt gtgatttgtt gaaagacaga ggttttctac
     3421 aaacgtcgat gcgacgtttt attcatcatc cgtctactga tgcggaaatc tcatgtgggg
     3481 atgaagtgat gctgtcgtgt ggctccggcg gacgcagtta cctgggtaat ttgcattatg
     3541 ccacccggta tactgtttgc cagcgttgta ttgccggaga gatagatgat tatatgggca
     3601 ctactgattt tacagtggct cgtaatggat ttattctttc tcaggaagaa cggcgacaac
     3661 gtttcatcat taaaaatctg atgtattata tggggcttga taaggccgaa tataagcgtc
     3721 gctttggaga atcaccggat aatgtgatgt tgtttcgaca gttagctgaa cggcaatgga
     3781 tagaaaatac ggataacggt cgtatttgtc tgacttccga cggaatggca tactccgatt
     3841 atattggtca gttgttcatt actcctgaaa taagagaact gatggaaact tattcttatt
     3901 gaacgaaata gaaatggaaa acgaaagctc tttactttcc ttcaggcata tatattatcg
     3961 cggcaaattg aatagctgca actatacctg ttcttattgt cctttcggca agaagtcgca
     4021 tctggcagat acgacacagg atgaacaggc atggaatcgt tttatagcag ctattgaaca
     4081 atggaaaggg gagccgttgc agttatttat tattccttac ggtgaagtat tgatccatcg
     4141 ttattatcgg aaaggaatgg tgcatttggc ggcattgcca caggtggccg gaatttcctg
     4201 tcagactaac ctttcttttc cggctaaaca ctggcttgat gagattcgtg tggctcccac
     4261 tgtgataagt aagataaggc tttgggctag ttttcatcct gagatgactt cggtagagaa
     4321 atttgcgcat cagattcata tactccatca tgcgggaata caggtatgtg tcggagcggt
     4381 aggaaatccc tctgcaaagg ccgtactcaa tgatttacgg aatgctcttt tgccggatat
     4441 ttatttattc attaatgcta tgcaagggtt aagggcacca ttaagtcagg aagatattca
     4501 gtttttcagt caactggata atctttttga gtatgacttg aagaatgctc cggtacaatg
     4561 ggaagtttgc gcaggaggaa gggataattg ttttatcgat tggaaagggg atatgtatgc
     4621 ttgtccccga agccgggtga agataggtaa tttttatcaa ggtgatggag ctgttgtgcc
     4681 gttatcttgc aagaggaagg tttgtgactg ttatattgca tttagtaacc tgaacaatca
     4741 ccctttacat cgaataatgg gagaaggggc attctggcga ataccggaca agccacttat
     4801 tacgactgtt ttcttcgatg tggatggaac actgactgat tcacagggaa aagttccaga
     4861 aagttatgct aacgctttgc gatatatggc acagtccgtt tccttatatc ttgccacttc
     4921 tctgtcgatg gagcaggcga agaaaaagct gggaaaggct ctttttgatt tattcagggg
     4981 aggagtgttt gcagatggag gtttattatc ttattcgcgg cagattaagt gtttgccggt
     5041 gaaagtatat ccggaggtat atggagaatc gtcaaaagtt actattcata gttatgaagg
     5101 agtggtttac aagtatagta tattggtacg tgataaagaa cagagagaat ctattcttac
     5161 ccggttgaaa gaaaatccct gccaggtctt tcataaagct ccgctgataa cagtcattca
     5221 tcctgaagcg agtaaaaaag aggggatgct tcagttatgt aaggctttgg gtttagcttc
     5281 tgaacacact ttagttgtag gaaattcgtt aaaggactgg ccgatgatgt ccgtggtttc
     5341 tcattcttgt gccgtaatga atgcggaacc cttattaaaa gaatgcgcac gttatacgct
     5401 gaatccggat cggttggcag ctttctttcg tttttctaac ggagatccta tagaccaaac
     5461 ctcgtctgat aatagttgat atatagctag ttacatcttc ataagaaaat aaaaaccggt
     5521 taaaatttgg taattatgaa aacaaagccc atatttgcag ccctgaaata gggacaggca
     5581 taaaaatcct catcggaggg tgctataata ataattatag tgctggataa gatgaatggt
     5641 gcaaatcatt cgcttgtccg gcactttttt ttgttgtaac aaaataagat aaagaggaaa
     5701 agtatcgaag aaactatgaa agagttagat ttgacacaag gaagcgtacc gaaggtattg
     5761 ttgcagtttg cagtaccttt tctgattgcc aatgtgctcc aggcacttta tggcggagct
     5821 gaccttttcg ttgtcggaca atatgatgat tcggcaagtg tggcagccgt agctattggt
     5881 agtcaggtga tgcagacaat tacaggtatt attctgggta ttactaccgg gacaacagtg
     5941 ctgattgcta ttgctaccgg agctaaagac aatcgaaaag tagcttttac tatcgggtct
     6001 tccgtatggt tgttttcaat aaccggcgta gtgctaactt tggtcatggt gctttttcat
     6061 agtcggatag cagaactgat gcatactcct gtcgaagcga tggtagatac gaaaaactat
     6121 attttggtat gctctctggg tattctgttt atagtaggat ataatgttgt atgtggtatt
     6181 ttgcgtggat tgggtgattc taaaacacca ctttattttg ttgggctggc atgtgtgata
     6241 aatatagtgc tcgattttat attggtcggt tatttccatt ggggggctac gggagcggct
     6301 atcgctactg taactgcaca aggagtcagc tttggaatag cgctctggtt cttataccgg
     6361 cacggattcc attttgactt ttcacggaaa gatattcgat tgaaccggaa tctgtctaaa
     6421 aagatcttgg tgttgggagc acctattgct ttgcaggatg ctttaatcaa tgtttctttt
     6481 ctgattatca ctgtcattgt caatcagatg ggagtcattg catctgcttc cctgggtgtt
     6541 gttgagaaaa tcatcgtgtt tgctatgctg cctccgatgg ctatatcatc ggctgtggca
     6601 accatgactg cacagaacta tggagcggga cttatcaaga gaatgaataa atgtctggct
     6661 tcggggattg ggattgctct tgttttcggt gtgtcggttt gcgtgtattc gcaattcctg
     6721 ccggagactc ttactgcttt ctttacgaaa gatgctgctg tggtggcaat ggcggcagat
     6781 tatttgcgag ggtatagcat cgactgcatc gtggttagtt tcgtgttctg cattaattct
     6841 tatttcagcg gacaaggaaa ctcgttattc ccgatgattc acagtctgat agccactttc
     6901 ctgttccgta taccgttgtc atactggttc agccagatag atagctcgtc gctgtttatc
     6961 atgggatttg ctccacccat ttcaacggtc gtttcattat tgatctgtat ctggtattta
     7021 cgatataccc aaaggaaatt atatttgaga ggcacaatga tgcctgctat gtcgaattag
     7081 gtgtttttaa gtgacatata ttaactaaaa tctattttgt atggaagctt atttgaagaa
     7141 actctgtttt gagtatcagg tggatgaaag agaagtgaaa gagctgttgg ctcgaatgga
     7201 aatggtgtat ctggataaag gagaaacgat tgcttctgcc acattgccag aacagagctt
     7261 gtacattatt gtttccggta ttttgcatac atataccact catgaaggag aagagagaac
     7321 caatcggttt ttctctgcgg gtgatgctgt gttatgctat aattcaagtc agtattctat
     7381 caagacactg acgaaatgtg ctgcttatta catcagtgaa gaggagattg aagagttgtg
     7441 tgcatcttca atttcatttg cgaatctggt ccgtcaactg atggagtatc agttttactt
     7501 taaagaggaa gaggatatga atgcccgcaa gctgacagta agggaaaggt acctctcttt
     7561 attggcggaa attccggata ttctgtacag ggtgccattg aagcacatta atcattactt
     7621 gggggcagat gtgaccagtt tgggatatct ggccggaagt tctaaatagg aaatataacc
     7681 tagacatatt tttctatgta ttccttatca gatggttcat ggcttattca atcgaatcga
     7741 atttgaaaag tctttggatt atttggtaag gaatactatt tttgtattct gaatgaaaaa
     7801 ctcaatacct cgatatactt tttataagca taagtatggg agtgaacttt tggtcgatgt
     7861 agtagaactg aagtatgtga agaagttcct ggctaaaagt gctgtccaca ctctaaatta
     7921 ttatgatatt acttttataa cagaaggtaa gggagctttt tcagtcgata accaaaccta
     7981 tgaagcaatt cctcgtgacg ttcttttctc taaaccgggg gaaatccgga actgggatac
     8041 tcatcatatc accaatgggt atgctctgat tttcgaagaa gaatttttgt ctttcctctt
     8101 taaagattct ttgtttgtac agcatctttc gttttttcag atagaaagtt cttcatcgct
     8161 actacatttg tctgatgagc tttatacacg catacttgaa accttgcatg atataaagat
     8221 ggagattgat tcgtatcaac agggcgatgt acacgttttg agagcattgc tttatgaagt
     8281 cctgatgttg ctggaccgtg cttaccttaa aatgacttcg atagaggagg gcagaagtag
     8341 ggaagtttcc aataatcatg taagtaaatt catgaatttg gttgctacac atgcaaaaga
     8401 gcaacattcg gttcaatatt atgcggataa gctctgcatt actcctaatt atctgaatga
     8461 gatgataacc tcgaccatgg gaatcagcgc aaaacaatat attcagagca aggtgatgga
     8521 agaggctaag aggctgcttg tttatacgga ctttcctata gctgatattg catttgaact
     8581 ctgtttttca acggtttctt attttatccg tagcttccgg cagcatacgg gagaaactcc
     8641 gttattgtat cgtaaagtac acaaaccgta aaaagtgcta tttctacctt tctttttatt
     8701 gcattgcttt cctggcattt ctctactttc gcatcagata ataaaccaat aataaaaagt
     8761 aaaatgatga gagacgcgga aaaaacagta ggcaacatga ttgataagct gaaaacagct
     8821 tttatcggtt cgatagacgg tgaaggattt cctaccatca aagcaatgct gcaacccaga
     8881 aaaagaaagg ggataaaaac tatttatctg acaacaaata cttcgtccat gcgtgtggcg
     8941 caataccgtg agaacaacca tgcgtgtatc tacttctgtg atacgagatt ctttagaggt
     9001 gtcatgctac gcggtacgat ggatgtcttg acggatagtg ccagtaaaga gatgatctgg
     9061 caggagggag ataccatgta ttatccggag ggagtgacgg atcccgatta ctgtgtattg
     9121 aagtttactg ctatttcagg acgtttctat agtaatttta aatcggaaga ttttgtggtc
     9181 gaataaggtg caagatgggg tgattggaat ggtaataacg gagtgtgtca aaacgcagat
     9241 taacgcaaat tatcgcagaa ataattttat aagtcgttga ttaatatatc aatataattg
     9301 gaataatctg cgataatttg cgttaatctg cgttttatta ttcattatga cacacctcct
     9361 tatatagtat ctatactatt cctcataaca caataagttc tgcaattggt tgatgatgtt
     9421 ttgtttccat tcttgcagga agtcagcaaa agcggcttca tcttccaaga ataaagatac
     9481 tatcaggttc ttggcaagaa atggatagct caataggctg tagacagtca gaaatacaat
     9541 atgtatcgga acctttttaa gtttaccgtc ttccattgct gtcagtatac tgtctttcac
     9601 ttgggataaa gcatctccga actgaagttc ttttgcagtg gcaagcaagt ggtttacatc
     9661 acgctgtatt tctccgcaaa tgaatctggg aagacaggga ttacttgtga aaagctcaat
     9721 atactcatcc agaatcatgc ttagtcgctc cataaatggg atatcctgtt ttactatatc
     9781 ctgtattttc ggcattaaag acatgactat cgagccgaac acggctttga acatcttatc
     9841 tttggttctg aaataataat gtaaagtggg ccggttgatt cctaccgttg cagcaatatc
     9901 actcatgctg gtctccacaa atcctttttc tataaaaagt tgttgggcag tttttattat
     9961 ttgctgctct aaatcgctat gttccgttgt agccataatt ttagttgttt atgttgtcaa
    10021 taaaaagtaa taatctgttt gttatgttca catcgctgac gctactgtca aagtctaaag
    10081 atagtatatt catttgaggg cacagcgatt ttatacgttt ttctattcct ttttctacaa
    10141 tgtgattggc aatgcatccg aaaggttgca agctaatgac atgattgact ccttgggaag
    10201 caaaggatag tatttcaccg gatatcagcc aaccctctcc aaactgggtg cccggggaga
    10261 tgacttgttt agctttttct gccttttcaa agattgattc gaacggcgtg aagtaattga
    10321 aatttttgcc gatttcattc actttattaa tctgcttctg gactttcttg tataaccagt
    10381 cgataacaaa gtcgggagtg agttttcgct gcaagtgttg gttctgtctc actttcaggt
    10441 tgacaaatcc ctgcatgaag aaatcactta tcagtggcgg aatcacttcg atcttctggt
    10501 tgatgagcca tgaggtgacg tccttttgag caaaagggtt gaacttcagg aatatttctc
    10561 caacaatacc tactttgtga caggatctct gttcacagat tttgttgaag tctctggcag
    10621 cgagatataa gtaactcaac aagtcctccg gtttattttt ctggatgatg ggctgtgctg
    10681 tatccagata aagatcgcgc agacgggcgg cctgtccccg ttctttctca cgaacgacgg
    10741 ctgcataata gaatttagcg atacaatcac tgtataacac agacgcaagt atgattggca
    10801 aaaccttgag ccagtttact ttaaaaccgg attgctcatt ttcaatacca ctgccgaaag
    10861 caagtgatac caccggtgta ttggtgtatc cattctcaat caatgccttt tttatcagtg
    10921 aaatatagtt gctggcacga cattgtccac cggtttgtgt gatggcaacg cacgtattgg
    10981 caggatcata acgtccgctt ttaaaggctt ttactatgtc gccgacaatc aatgttgccg
    11041 gataacatac ctcattattg gagtatttca atccccagtc gcaagatgcg gtgtcgctca
    11101 acggtaacgt ttccatttca tatccggcca ctttcatgat ggatggaatg agtggtgaaa
    11161 tgaaaggcgt aaagaatgga gcgaggattt tcttcttttt gtctttcttg gtgaaaggag
    11221 cagttgaaac aaatggctcg ggatctttcg cttgagaatg tttcaaactg aaattcaagc
    11281 tttccaccaa cgagcggact cgtaatttga tggagccgat attattaaca tcgtctatct
    11341 tgagcaaagt aagattcttg ccgtatcgtt tcagcaagtt acgtacttca tctataagga
    11401 aagcatccgg accgcagcca aaagaagtca tctgcatata ttgtatgtca ccctcttgca
    11461 ttgccgccca cttggttgct ttcagaatac ggttggtaaa tgcccattga gagaggtaat
    11521 gagtcttttc caatgaaatc tcctgctggc ggacaatatc atcagttatc acataaactc
    11581 ccatcgcagc aatcatgtcc gaaaccttgt gctgtatcag tggatcgcta tggtaagggc
    11641 gtccggcgag taagataatc agtttgtgtt tttcccgtcc ctcgttcaga acttcctgat
    11701 tataggcagc aattttttct tcgaaagcat attgttcctg taatgcgcgt gagaaggcat
    11761 ttttgcatac ctcatccctg atacccaaag atttcagata ttcatagcat tgtttataca
    11821 gcaatgcttc atctttgaag gtgatagtcg gagcatctat cggtatattc tcttcctgta
    11881 cacttttgat gacttccgaa taaccggaaa cgatggggca attatagctg ttttgctgtt
    11941 gcttatcctt tttctcgaaa acaacgaacg gcataaatat ccggttgacg ttttgcagtg
    12001 tcaggttacg gatatgactg tgcacaagtt tggcagggaa gcagatgtta tcagacatca
    12061 ccatgccggc agcagtctcg tatttgctga atgtagaggg ggccgacaac tgtacctgaa
    12121 tgccgcaagc agtaaataag gtatgccaga aagggtattc ctcatacata ttcagaatac
    12181 gtggaatgcc tatggtaaat aggggttgtg gaatgtctgc gctccggtcg aataataatt
    12241 ccagcttttt atcatacgta ttgatgcctt tgtccgcatg gcttccttta ttggaaaata
    12301 ccttttcaca tcggttgccg gagaagtaat ggttgtcatt gttgaacgta tatcgcataa
    12361 tggcgcactg gttctcgcac ccccggcatt gaagttgctt ggaagtatat tgcgcccatt
    12421 ggagcatctc gttcagctcc gtcacccggg cattttcgat ttgtttggca tatagggcac
    12481 aaccaagagc acccatcaat tcaggacagt tactgcggaa ggtttgtttc ccggtcagct
    12541 tttccagact tcgtacgatg gaatcattac gcatggttcc tccctgcacg acaatatggt
    12601 cgccaagtat ctccgtgtct tttaattgca gaaccttata caggcagttt ttaacaacgg
    12661 aataagataa tccggcagct atatccgcta cggacgctcc ttcccgaagt acctgtttta
    12721 ctttggagtt catgaagact gtgcaacgtg tacccagatc acatggtgct tgcgaaaaac
    12781 aagctgcttt ggcaaagtcc tccacactgt aatccagcga ttgcgcaaat gtgctgataa
    12841 aagaaccgca accggaggaa caggcttcat tgatttcgat tctgttgatt actccgtcgt
    12901 tcacaaagat ggctttcata tcctgccctc caatatccag gataaaagaa acttctttgc
    12961 tgatatgttt ggcagcagca taatgagcga tggtttcaat gattcccgca tccatgtgga
    13021 aagccgcttt tatcagatct tctccgtaac cggtagaaca tcctcctttt atgcgcaggg
    13081 tagttcctcg tctccggcat tcttcatata gtttctgcaa gccgttctct actgttttta
    13141 tagggtttcc gttgttgtcg tgataatagg agtaaaggat acgatgattg ttgtcgagta
    13201 ctacgatttt ggtggtagta gagccggagt ctatgccgat agttgcttcc tgtaatccgg
    13261 gacgcagact ggcatattga attttatact ggtctttttc ttttttccat gaccgatatt
    13321 cttcctcact gtcgaatata ggagaaagat cactctggaa aggtgaggta acacttagtt
    13381 tgttttctat tacctgtatc aggttggaga gatgaatact ttcttcattg ttctctgcca
    13441 atgctgctcc ccaggcaggg atcagatttc ctttttccgg taatatgaaa tctgtatctt
    13501 gtgacagatt cagatagttg gcaaatgctt ttcgaagggc cggaataaaa gtcaatgggc
    13561 caccgcagag taataccgga gctacgatat tgcaaccgcg tgcaagtgtg acagtggtct
    13621 gtacggctac tgcatggaaa atggaagctg ctatattttc tttagatata tttttggcta
    13681 tcagattctg tatgtccgtt ttgcagaata ctccgcagcg tgaagcgata gagtatacct
    13741 gattggaacg aagtgctagt tcattcaatt cgtcgatgga gactccaagc agaatagcca
    13801 tctggtcaat gaaagccccg gttccgccgg cgcaatttcc attcatgcgc aggtctgtag
    13861 cctgtccgtc ctgaaagaaa acaactttcg catcttctcc tccaatatcg atcatagtgg
    13921 ctgtgtgcgg atgctcccgg cacacatagt ttgttgcagc tacaacctct tgcacaaacg
    13981 gcagagagca tttctctgaa attcccattc caacagagcc cgtaatgtgg aaagataaag
    14041 gaatatcacc caactgttcc tttatttgat aaagaaatcc gagtaaacat tcttgtattt
    14101 ttgcctgatg ccttttgtat ccggaaaaca agactgtagt tccatcttta tccaatacta
    14161 ccatcttagt ggtagtagag cctatatcta aacccacttt atatacattc atataccaaa
    14221 tatcttaaat tagacctcgt gtttgacatc tgtgtcagac gcaaatgtat gtaaaaatat
    14281 ggtagatacg gcaaatcgta attgaagttt ttgatttaat taacgaattg ggaaaaaaga
    14341 aagatggaat gtgagggagg aaaacgatcg tgtaaaaaag acgtaaatga ataattgtgt
    14401 atttatatta cttgttgggt tgtagtagat cttttatggt gaatcttaga aatcttgttt
    14461 actctatttt tgacaaaagg taacgtggct tttaataaac ccggattctg tttataataa
    14521 actttttgat agttttagta aaacggtatt cgagtttatt ataaactatt gtagaacagt
    14581 tctaggatca gacgagagat tttaagctga attataaaca aaatgaggtt gtgtcaaaac
    14641 gttggcacaa cctcttttat attttacagt tctgctatat tttcttttgg ctatgctgct
    14701 ttttcctcat gcatttggca acaagttgct atattccaat tatatcgggt t
//
