LOCUS       c00086_gnlPro..        14010 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PNKDKHOP_87.
ACCESSION   c00086_gnlPro..
VERSION     c00086_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:59:52
            Original ID  :: gnl|Prokka|PNKDKHOP_87
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14010
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..180)
                     /locus_tag="ctg86_1"
                     /transl_table=11
                     /translation="MDLAENRFGKTWKHFLEALKVDYNCSLADVCRDQHTTFGGMSSWM
                     SRRGYSVKQAKADVV"
     protocluster    1..14010
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[496:4010]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      497..4010
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14010
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14010
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(497..1252)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_2"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-11, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 8.1e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(1289..3268)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.6; E-value:
                     3.8e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.5e-62, bitscore:
                     202.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-36,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEINGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLHKEPLVYEAIKVQTRNYKS"
     CDS             complement(3306..4010)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_4"
                     /sec_met_domain="SucD_FumR (E-value: 4.9e-131, bitscore:
                     427.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             4153..4269
                     /locus_tag="ctg86_5"
                     /transl_table=11
                     /translation="MCQYASQYVRMVQLIGRLVGWDCLLYLSDFLTAGCFFA"
     CDS             complement(4222..5091)
                     /locus_tag="ctg86_6"
                     /transl_table=11
                     /translation="MPRDSFCIQYTNCTGCPKNVENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEHPGITLRERQIVLQAIGSKVEILALTDVEYVIYWFNELPLLCEDR
                     YKEMMEQAEAPLTYTPLIMSERLYHLVTSMPEFLAEENPCSKYIDLKCKELVFLITNFY
                     PLPQLGSFFYPISTYTESFHYFVMQNYSKVKNVEEFAHLGGYTTTTFRRLFKNLYGVPV
                     YEWILEKKREGILEDLQHTKMRITEICNRYGFDSLSHFAHFCKDSFGDTPRALRKKAAG
                     GEKIGKVQ"
     CDS             5365..6330
                     /locus_tag="ctg86_7"
                     /transl_table=11
                     /translation="MLMLRKIVFFFFFLFVGLSLFAQQDYMVSSYVRGNFYNRGRISTE
                     SLRASDDLIFLNVHPNKDGSLSFENPRAFQGKGVTTWEGLIKSVRAKVKGTKVKIRLGA
                     SSGEWKAMVADEAARTTFAKNIKTVLEKNKLDGIDLDFEWAENEKEYKDYSLAILKMRE
                     VLGNKYLFSVSLHPVCYKISKEAIEAVDFISLQCYGPSPVRFPIEKYCSDIQMVLEYGI
                     PKEKLVAGVPFYGVTKDNSKKTEAYFNFVQNGLVTSPAQNEVIYQGDTYVFDGQDNIRI
                     KTRYAKEQKLKGMMSWDLATDLPLSDSRSLLKTMTEELRE"
     CDS             complement(6660..10778)
                     /locus_tag="ctg86_8"
                     /transl_table=11
                     /translation="MKKHIASILFLCLLSVSQSIAQSHSIKRLGIEQGLSNNYVISIAQ
                     DKQGFLWFATEEGLNKFDGTRFITYYKNDLSQSSQGITGNELNRVYADNKRPIIWIATQ
                     RDGLNAYNYNKQAFTAYSHNPDDPHSLITNDVTDIAPSAQHEDGLWISTYYRGIEYLDI
                     NSGQFTHYNKNTVPALSCEQTWTVLDGGDGNLYIGHVGHGFSILSLKDKNVKNFQNHSG
                     DPKSLPGNDVRCLTKDTNGNIWLGTDKGLALFNVADQSFITFKNNKNDRYAALCNRILA
                     IKQLNDGKLWIASELNGITILDLKQSMFLSPEQVSLEYIQEGDDSRSLSNASARCIFQD
                     SFDNIWIGTWGGGINFISRKPPLFTTLSYSPIPNNENSLNNKVVSSLCTDRQRRIWIGT
                     DGGGINVFEGDKRIAIYRKETGDIPSNFILTALQDSKGNLWFGSFQGGISYYDTRNKRF
                     RSISLMGQYNQDVRTIYEDTQHNIWVGYSGGIIVLNPLNMEIIRHYNTENSELHSDFVR
                     SIAQDEKGRFWIGTFGDGLGVYTPDLQKIKTFVQRDGFCSNTVNQIIQDKHKRMWIGTG
                     EGLVCFPSTDALTYKTYQRKDGLTNTNICAITEDKKGNIWFSNNKGVSCYVTSKDCFYN
                     YGHSDDVPAGSFSSGCVTQNNNGWIYFGSINGVCCFNPDIAMNEQPTPSAVITEMKILG
                     RLSNLENNDMIINLSKGQNVELSHAQNSFGLTFNVQNYSLVNQVEYVYMLKGLENSWYT
                     VNENNSVTFRNIPPGKYEFLIKARVHNQEWPEEATSLTIRVNPPLWLTWWAKLIYIWVS
                     ISIIYLILHAYKKKLDLESLYTLEKKNHEQEQELNQERLRFYTNITHELRTPLTLILGP
                     LEDMQKETSLPAKQAQKLSVIHQSALRLLNLINQILEFRKTETQNKKLCVSKGNIAPLI
                     YEIGLKYKELNQKTKIDFQIQIEKEEMLLFFDKEIITIVLDNLISNAIKYTEQGRVTLS
                     LYQTMRNEVAYTEIKVSDTGYGISAEALPHIFDRYYQESGKHQASGTGIGLALVKNLVT
                     LHEGEIRAESIQNEGSTFYISLLTDNIYPNALHADSTEPIQEDTNQEASLEYPQETTLD
                     IGKPILLIVEDNEEIQKYIAESFADSFEVLTAYNGEEGKQQALSRIPDIVVSDIMMPVM
                     DGIILCRQLKEDVRTSHIPVILLTAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINN
                     LLESRKKLIAQFQTQSVPGNQADLKEKRIVIAEALSKLDNEFIEKITLLIEENLSSEKI
                     DITYLSDKMCMSGSTLYRKMKALTGLSTNEYIRKVKMQNAERLLLEGKFNISEIAYKVG
                     MNSTGYFRQCFKEEFGVSPSDYLKQIIQS"
     CDS             complement(10775..10882)
                     /locus_tag="ctg86_9"
                     /transl_table=11
                     /translation="MQRSYINRAMHDLHTLNKIFIPIFELVNETNNYES"
     CDS             10998..12401
                     /locus_tag="ctg86_10"
                     /transl_table=11
                     /translation="MKAKLLQSTVLWTFLSAATLFVGCSDDEDYRDVDGQSPTLELTSD
                     HIRTLTGYEFKIAGKIADKDGIRSINLQCAELYLDKTIELSALYSEPLYEYNLNYGFTI
                     PEKTKGDSFTIKVTVTDLGGRTSTNDVLVTMDGDYTEPVLTPSIGLLSDNINIVLSEGT
                     SKTFRFTAEDNKELDYLELAVPDLEILERQDIEEGEKKGTLNTTVVFPSDKTGTYTLVI
                     RAVDTFGNVAEKNYSVLVSRVKDYENMYLVDFEGTDSKLLTGNDVWGVPMPIERVTNFT
                     YKARCYSPAPNTPIRFITSKYSFSICFGDDKNNPGKLTGISEDVQPIILPEKSYYEINF
                     NTEEGTYTVEAYSPGTPIIDGLKMGFVGGWFDGAKGWDGPKNVYELTQDPDNPHCLTAE
                     LTWSKQDSFDVTITPYNANGDWLEPGWRFDGKNESFATNTNDSSKKVPAGKYTFIFDTH
                     LVQSKLLKK"
ORIGIN
        1 gaccacatct gccttggctt gtttaacgct atagccccgt ctggacatcc aggaactcat
       61 accaccaaaa gtggtatgct gatcgcggca aacatcggct aaagaacaat tgtagtctac
      121 tttcaatgct tcaaggaaat gtttccaagt ttttccaaat cgattttctg ctaaatccat
      181 aatgcttcat ttttatacat agcaaaaata taagaatgaa aaaagggcga caagatagaa
      241 tcgcggagac gcttacgcgg taacgaatga ttttacctta tttcaatcct cgctttcacc
      301 cgtaattctc tcattcataa cagttttggc tataaggtga aatcggtgaa acttatgaat
      361 taaaagttca tgttactgat ccgtattaat aataattgtg atctactcat acataaagaa
      421 atcccctgtc gaactagtcg gcaggggatt ctgtcattaa tcaaattaag ctctcgctat
      481 tgaaatctag cagtttctag tcttttaatt ttgcgatgat gaagtcgcgg ttcaagcgag
      541 cgatgttgct gatagaaata ttcttcggac attcagcttc acaagcacga gtgtttgtac
      601 agttaccgaa tcccagttca tccatctttg acaacatagc ttttgcacgg cgcaaagctt
      661 ccggtttacc ttgcggcaac aagttcaact ggctgacttt tgcagaaacg aacaacatag
      721 cagaaccatt cttacatgca gctacacaag caccgcaacc gatacaagaa gcagcatcca
      781 tagcttcgtc agcgataggt ttcgcgatca ggatagcgtt agcatcctgc ggagcacctg
      841 tgcgtacgct tacataacca ccagcctgca taatcttgtc gtatgcagta cggtctacca
      901 tcaagtcttt gatgacaggg aaaccagccg aacgccaagg ttcaacagtg atggtatcac
      961 cgtcgttgaa acgacgcata tagatttggc aagtagtagc acctgttgca ggaccgtgcg
     1021 ggtgtccgtt gatgtaaaga gaacacatac cgcagatacc ttcgcggcag tcatgatcga
     1081 atactaccgg ttcttttctt tcgctgatga gctgttcgtt cagaatatcc agcatttcga
     1141 ggaaggaagt atcaccgggg atatctttca tttggtaggt ttcaaaagca cctttagctt
     1201 tcggaccagc ttggcgccat accttcagtg taaatgatat atttttatcc attttcttct
     1261 aattctttta aatgtttaac ttcaccgatt agctcttgta gttacgagtc tgaaccttga
     1321 tagcttcgta taccagcggt tctttgtgca ataccggagc cttttcatcg tcaccttgat
     1381 attcccaaca tgctacatag aagaagtttt cgtcatcacg tttagcttct ccttcttcag
     1441 tctggtattc ttcacggaag tgaccaccac aactttcgtt acggttcaat gcatcgtaag
     1501 caacaagctc acccattgtg atgaagtcgt acagacggat tgctttgtca agctctacgt
     1561 tcataccttc tttggaaccg gggataaaca gattcgtttc gaattccttg cggatttctt
     1621 tcaattcggc aatacctttc ttcaagcctt ctgccgtacg tcccatacct acatattccc
     1681 acatgacatg acccagtttc ttgtggatag aatcaacaga ttctttaccc tggatactca
     1741 tgaacttgtc gatcttagct tgaactgctt tttctgcttc agcaaattca ggaagatcag
     1801 tagagaaacg aggaacagtg atttgatctg ccagataatt ctggattgta taaggcaata
     1861 cgaagtaacc gtcagccaaa ccttgcatca atgcagaagc accgaggcgg tttgcaccgt
     1921 ggtcggagaa gttacattca ccgatagcga acagaccctt gatagtggtt tgcagttcgt
     1981 agtctaccca gattcctccc attgtgtagt ggatagccgg ataaatcatc atcggattat
     2041 aatattttac gccattaatt tcttttgcca gttcgcccgg attaacgtca gtgatttcct
     2101 cgtacatatc gaagaggtta ccataacgtt ggaggacaac atcgataccc aaacggttga
     2161 tagcttcaga gaaatcgagg aatacggcta aaccggtgtt gtttacaccg aaaccggcgt
     2221 cgcaacgttc tttagcagca cggctggcaa catcacgcgg aaccaggtta ccgaatgccg
     2281 gatagcggcg ttccaagtaa taatcgcggt cttcttccgg aatatcactt cctttgattt
     2341 cgcctttctg aagtttcaca gcatcttctt ttttcttcgg aacccagata cgaccgtcgt
     2401 tacgaagaga ttcagacatc aaagtcagct tagactgctt gtcaccgtgt acagggatac
     2461 aagtcgggtg aatctgaacg tatgcagggt tagcgaatac agcacccttg cggtagcaag
     2521 agatagcagc tgtacagtta caacccatag cgttggtaga caggaagtaa gcgttaccat
     2581 aaccaccggt agcgataact actgcgtgag cggcgaaacg ttccaattca cctgttacaa
     2641 ggtttttagc gataataccg cgagcacgtc cgtcaacgat gacaacatcc tgcatttcat
     2701 aacgagtgta cagtttaaca gtacctacgt ttacctggcg gctcaatgca gagtaagcac
     2761 ccagcaataa ttgctgacct gtctggcctt tagcgtagaa agtacgtgat acctgtgcac
     2821 caccgaaaga acggttgtcc agtgtaccac cgtattcgcg agcaaaagga acaccttgag
     2881 ctacacattg gtcgatgata gcgttggata cttcagccaa acgatatacg tttgcttcac
     2941 gggcacgata gtcgccacct tttacagtat cgtaaaacag acggtaaacc gagtcaccat
     3001 cattttgata attttttgca gcattgatac caccctgtgc agcgatagag tgtgcacgac
     3061 ggggagaatc ttgaatacag aaattgaata ctctgaaacc catttcacca agtgaagcag
     3121 cggcagaagc acctgccaga cctgtaccca caacgatgat gtccaaacga cgtttattag
     3181 cgggattcac caatttctgg tgagctttat agttggtcca tttctcagcc accgggcctt
     3241 ctggaatttt tgaatctatc ttgatcataa tattatttac aatttaatca tttacaattt
     3301 actatttagc aagcaccgcc acaaatcagt gttttcacga agaataccac tactaccagt
     3361 gcgaaaccga gtacaacaat cgtagaatag atgttagaaa tgcatttcca acgattgatc
     3421 catactttgt tgttccatcc cagtgattgc atagagctcc agaagccgtg agtcaggtgg
     3481 aaccacaacg caaacagcca aacgaggtaa agaactacgt aaaccgggca agagaaagtc
     3541 tgctggatgt gataagcacc attggcagca taagccagcg tcagtgtatc agcgtgcatg
     3601 cccatgttgt gcatcagttc cggcaactgc atttttgccc agaagttgaa gaggtgcaaa
     3661 ccaagaccta cgatgacgat cagacccagc accaacatgt tttgagatgc ccattctaca
     3721 gttttcggtt tgtcaaccac tgcatagcgt tcgctaccac gcgctttgcg attctgcatg
     3781 gtcagccaga atgcgtagat gatgtgaatc acgaaaagag cagccagtcc tgcggtagcc
     3841 actaatgcat accagtttgc tcccaggaac tcacaaatca tgttgtaacc atcagccgag
     3901 atgatcgcaa ccaagttcat cgccatgtga aatgttagaa acaggacaag ggcgataccg
     3961 gtaacgctca tcaccacttt ccttcctaca gatgaattac ttaaccacat aaatgattga
     4021 atttaaatta tttaattgtt agaactaaaa tttcgacgtt ttacacctct tacagactgc
     4081 aaaaataggg gaaatagatt gattgagcaa ggaattaaag aaataattct ttaataatgg
     4141 atcaatgcgc caatgtgtca atatgccagc cagtatgtac gcatggtgca actgattggc
     4201 agattagtag gatgggactg tttattgtac ctttccgatt ttctcaccgc cggctgcttt
     4261 tttgcgtaga gcgcgtgggg tatcgccaaa agagtcttta cagaagtgtg cgaaatgaga
     4321 cagagagtcg aatccgtatc tgttacagat ttcagtgatt cgcattttgg tgtgctgtag
     4381 gtcttccagg attccttccc gtttcttttc cagtatccat tcgtatacgg gcacaccata
     4441 gaggtttttg aatagtcggc ggaaagtagt ggtcgtatat cctcccagat gcgcaaattc
     4501 ttccacgttc ttcaccttgc tgtaattctg catgacgaaa tagtggaaac tttccgtata
     4561 agtgctgatc ggatagaaga atgaacccag ttggggcagc ggatagaagt tggtaatcaa
     4621 gaaaaccagt tctttgcatt ttaagtcgat atacttgctg caagggtttt cttcagcgag
     4681 gaattcgggc atactggtga caaggtggta aagcctttca ctcataatca gtggagtgta
     4741 ggtcaaagga gcttccgcct gttccatcat ttccttatat cggtcttcgc aaagcaaagg
     4801 cagttcgttg aaccagtaga taacgtattc cacatctgtc agtgccagta tttcgacctt
     4861 ggagccaata gcttgcaaaa caatttgtct ctcgcgtaac gttattccgg gatgctcttc
     4921 gctattgata agtaattcgc cctttatcat aaaaagcata caattctgcg tacacttatc
     4981 cttggggata tgctctcctt taggtaagtt tctatataca aggatattct caacattttt
     5041 tggacatccc gtacagttgg tatattgtat gcaaaatgaa tctcttggca tgagttttat
     5101 gcgtgattta ttatcttaac ggaacaaaga taggcttttt ttgcggaaaa tggaactctt
     5161 tcttttattt atgttttagt agaaacctgc aaatattatt cttatccctt tggatgatgt
     5221 tagagaattc aatatttatc tgttgtaaat ttctgaatag aaaactttat gttgattttt
     5281 ggaagtatta tagttgtttt tgaacatctg tttccctttg atatgcgtat ttttgcaatc
     5341 taaacgtttt aattatcaat cattatgcta atgctaagaa aaattgtatt cttcttcttt
     5401 tttttgtttg ttggattatc attgtttgca cagcaagact atatggtcag ttcttatgtg
     5461 cggggtaatt tttacaaccg tggtcgtatc tctacagaaa gcttgcgggc aagtgacgac
     5521 cttattttct tgaatgttca tcctaataaa gacggatcat tgtcatttga gaatccacgt
     5581 gcatttcagg gaaaaggggt gaccacttgg gaaggtttga ttaaatcggt tcgtgcaaaa
     5641 gtaaaaggta caaaagtgaa aatacgtttg ggagcttcca gtggcgaatg gaaagcgatg
     5701 gtggccgatg aggccgctcg tacgacgttt gcaaagaaca taaagactgt actggaaaag
     5761 aataaactgg atggcattga tcttgatttt gagtgggcag aaaatgagaa agaatataaa
     5821 gattatagtt tggctatcct gaagatgcgg gaagtgttgg gaaacaagta tcttttcagt
     5881 gtatctctgc atcctgtttg ttataagatt agtaaggaag ctattgaagc tgttgatttt
     5941 atttcacttc agtgctatgg tccttcaccg gttcgttttc cgatagagaa atattgttcg
     6001 gatatacaga tggtattgga gtatggtatt ccgaaggaaa aactggtggc aggagttcct
     6061 ttttatgggg tgaccaaaga taattcaaag aagacagagg cttatttcaa ttttgtacag
     6121 aatggattgg ttacgagtcc tgcacagaat gaagtgatct atcagggaga tacttatgtg
     6181 tttgacggtc aggataacat tcgtatcaaa acccgttatg caaaagaaca gaagctgaaa
     6241 ggtatgatga gttgggattt agctacggat ttgccgttaa gtgatagcag gtcattacta
     6301 aagacaatga ctgaagaatt gagggaatga cttagttcgc acgactgcta cttgtaaatc
     6361 ctttttgtag atgctgttta acaggttctg ttttaatagg ttcctcccct cctttattat
     6421 aattagattt ataaagaatg tgttaaaaca cttttcttta gagaaatact cctgccgcat
     6481 cgtttgaagt ggcctccaaa agttggaggt ttataaatta gcaagataga taaagagttc
     6541 ggtattagca ccggactctt tccttttaat ttaggcatta tgactttacc ctcttctttt
     6601 tcggtaggag cttaatttgt ttctcaaaac gtattaagtg taaatggctc tctccctttt
     6661 tatgattgta tgatctgctt caggtaatcc gaaggcgaga cgccaaattc ctctttaaag
     6721 cattgacgga aataccccgt actgttcatt cctactttat aggcgatttc agagatgttg
     6781 aacttccctt caagcaataa acgttctgca ttttgcattt tcactttccg gatatattcg
     6841 ttggtcgata atcctgtcag tgctttcatt ttccggtaga gggtggaacc gctcatacac
     6901 atcttgtctg aaagataggt aatatcaatc ttctccgaag agaggttttc ttcgattaaa
     6961 agggtgattt tttcaataaa ttcattatcc agcttgctta gagcttcggc gattacgata
     7021 cgtttttctt ttaaatctgc ctgattgccc ggaacggatt gtgtctggaa ttgagctatc
     7081 agtttctttc ttgattccag cagattattg atacggctac gcagcagaga agcactgaaa
     7141 ggctttgtca gataagaatc ggctcctacc tcatatcctt cttctttatc ttgcagagag
     7201 tctttggctg tcaataggat gacagggata tgactggtcc gtacgtcctc tttcaattgc
     7261 cggcagagaa tgataccgtc catgacaggc atcataatat cgctgactac aatatccggg
     7321 atgcggctaa gagcttgttg cttcccttct tctccgttgt aggcagtgag tacttcgaat
     7381 gaatctgcga aggactcagc gatatatttc tgtatctctt cattgtcttc tacaatcaac
     7441 aggatcggtt taccgatatc cagtgtggtt tcttgtggat attcaaggct tgcttcctga
     7501 ttcgtatctt cttgaatcgg ttctgtagaa tctgcgtgta aagcattggg atagatatta
     7561 tccgtcaata ggctgatata gaaagtactt ccttcgtttt gtatgctttc tgcccggatt
     7621 tctccttcat gcagggtgac cagatttttc actagggcca agccaatgcc tgttccggat
     7681 gcctgatgct tgccgctttc ctgataataa cggtcaaaaa tatgtggcag ggcttcagca
     7741 gaaattccat atcccgtgtc actgactttt atctctgtat aagcaacctc attgcgcatt
     7801 gtctgataca aacttagagt gacgcgtccc tgttccgtat atttgatcgc gttggaaatc
     7861 aggttgtcca aaacgatggt aatgatttcc ttatcaaaga aaaggagcat ttcttctttc
     7921 tctatctgaa tttggaaatc aatcttggtc ttttgattta gttctttgta tttaagccct
     7981 atctcataga tcagaggagc gatattgcct ttgctgacac acaatttctt gttttgtgtc
     8041 tctgtcttcc ggaattccag tatttgatta atcaagttga gcaaccgtag tgcactctga
     8101 tggatgacag ataacttctg ggcttgtttt gccggaagtg aggtctcttt ttgcatatct
     8161 tccaaaggac cgaggattaa ggtcaatggc gtacgcagct catgggtaat attagtatag
     8221 aaccgcaaac gttcctggtt caattcctgt tcttgctcat ggtttttctt ttccagcgta
     8281 tagaggcttt ccaaatccag cttcttttta tatgcatgca ggataagata aatgatgctg
     8341 atagataccc aaatatagat aagttttgcc caccatgtca gccaaagagg gggattgaca
     8401 cggatggtaa gtgaagtcgc ttcttccggc cattcctgat tatgtaccct tgctttgatg
     8461 aggaattcat attttcccgg aggaatgttt cggaaagtga cgctgttgtt ctcattgacg
     8521 gtgtaccatg agttttcaag ccctttcagc atataaacat attccacttg gttgactagt
     8581 gaatagtttt gtacgttaaa tgtaagtcca aagctatttt gcgcatgact taattctaca
     8641 ttctgtcctt tggataaatt gataatcatg tcattatttt ccaggttgct caatcgtccg
     8701 agtattttca tttccgtaat aactgccgat ggagtgggtt gttcattcat tgcaatgtca
     8761 ggattgaagc aacatacgcc attgatagaa ccgaaataga tccatccgtt gttattttgt
     8821 gttacacaac cgcttgagaa acttccggcc ggaacatcat cagagtgacc ataattgtaa
     8881 aaacagtctt tacttgtaac ataacaacta acgcctttat tattgctaaa ccatatatta
     8941 cccttcttgt cttcggttat tgcacagata tttgtattgg ttaaaccatc ttttcgttga
     9001 tatgttttgt aagttaatgc atcggttgaa ggaaaacata ctagtccttc tcctgttcct
     9061 atccacatcc ttttgtgctt atcctgtatg atctgattga cggtgttgga acagaaacca
     9121 tccctttgga caaaggtctt gattttctgt agatcaggcg tgtatacgcc aagtccgtct
     9181 ccgaaggttc caatccagaa gcgccctttc tcatcttgag ctatagaacg tacgaaatcg
     9241 ctatgtagtt cactgttttc tgtgttgtag tgtcggataa tttccatatt aaggggattc
     9301 aatacaatga ttcctccgct gtatcctacc cagatattgt gttgagtatc ttcgtagatc
     9361 gtacggacat cctgattgta ctgtcccatg agagagatgg aacgaaatct tttattccga
     9421 gtatcataat aactgattcc tccttgaaaa gaaccgaacc atagatttcc ttttgaatcc
     9481 tgcaaagcgg tcaatataaa attcgagggg atgtctcctg tttcttttct gtaaatagca
     9541 atacgtttgt ccccttcaaa tacattgata ccacctccgt ctgttccaat ccatatacgt
     9601 ctttgtctgt cggtacagag actgctcact actttattgt tcaggctgtt ttcattgtta
     9661 ggaatcggag aataacttaa tgttgtgaat aagggtggct ttctgctgat aaaattgatt
     9721 cctcctcccc atgtgcctat ccagatgttg tcaaaagaat cttggaatat acaccgggca
     9781 cttgcattgg agagacttcg gctatcatcg ccttcctgaa tatattctag ggaaacctgt
     9841 tcgggtgaga gaaacatact ttgtttgaga tccagtatag taatgccatt aagctctgaa
     9901 gcgatccaaa gtttgccgtc atttaattgt ttaatagcta atatccgatt gcataaggct
     9961 gcatatctat catttttgtt attcttaaaa gtgataaagc tttgatcggc aacattgaaa
    10021 agagccaggc ctttatctgt cccgagccat atattaccgt ttgtatcttt agtgagacat
    10081 cgcacatcat tgccgggcag gctcttcggg tctcccgaat gattctggaa gttttttaca
    10141 tttttatctt taagtgaaag aatactgaat ccgtgaccga catgaccgat gtataggttt
    10201 ccatcccctc cgtccagtac agtccatgtt tgttcgcaag ataaggccgg cactgtattc
    10261 ttgttataat gagtgaactg cccactgtta atatcgagat attctatgcc tctataataa
    10321 gtactgatcc acaggccatc ttcgtgttga gcagaaggag cgatgtctgt tacatcattt
    10381 gtaatcaaac tatgaggatc gtccggatta tgtgaataag ctgtaaatgc ttgcttgttg
    10441 taattatatg catttaatcc gtcccgttga gtcgctatcc atataatggg acgtttattg
    10501 tcagcgtata cccgattgag ttcattacca gtgattcctt ggctactttg cgataagtca
    10561 ttcttataat aggtaatgaa acgggtgcca tcgaatttat taagtccttc ttctgtagca
    10621 aaccataaga agccttgttt atcttgtgcg atactaatca cataattatt agataatccc
    10681 tgttcaatgc ccaatcgttt gatagaatgg gattgagcta ttgattgaga aactgatagc
    10741 agacacagaa ataaaataga agcaatgtgt ttcttcatga ttcgtaatta ttcgtttcat
    10801 ttacaagctc aaaaatagga ataaatattt tatttagagt atgcaaatcg tgcattgcac
    10861 gatttatata gcttctctgc atgattttta tcggtttata tagttggaat cgtttacatt
    10921 tgtcatgtcg atttgccgat attttatata ttgagaagtc gtaccgagat aatattaatc
    10981 attaaatact aattattatg aaagctaaat tgttgcaaag cacggttttg tggactttcc
    11041 tttcagcagc gaccttgttt gttggatgta gtgacgatga ggactataga gatgtagacg
    11101 gacaatctcc aactcttgag ttaacgtccg atcatatccg tacattgaca ggctatgaat
    11161 ttaaaattgc aggtaaaatt gcagataaag acggtattcg ttctatcaat ctacaatgtg
    11221 cagagcttta cttggacaag acaattgaat tgtcggctct ttattcagaa ccattgtatg
    11281 agtataatct gaattatggt ttcactattc ctgaaaaaac gaaaggtgac agttttacta
    11341 taaaggtaac agttaccgat ttaggtgggc gtacatcaac aaatgatgtc ctggttacga
    11401 tggatggtga ttatacagaa ccagtcttga ctccgtctat tggtctttta agtgataata
    11461 ttaatattgt gttgtccgaa ggtacttcta aaacattccg gttcactgca gaagataata
    11521 aggaattgga ttatttggaa ttagctgttc ctgatttgga aatcttggaa cgtcaggata
    11581 ttgaagaagg agagaagaaa ggaacattga atactactgt tgtatttcct tctgataaga
    11641 ctgggaccta tacattggtt atacgcgctg tcgatacttt cggtaatgtt gcggaaaaga
    11701 actattcagt acttgtttcc agagtgaaag attatgaaaa tatgtatttg gttgattttg
    11761 aaggaacaga cagtaaatta cttacaggca atgacgtgtg gggagttccg atgcctatag
    11821 aacgagtaac gaatttcacc tataaggctc gttgttattc acctgctcca aataccccga
    11881 tccgtttcat tacaagcaaa tatagcttca gcatctgttt tggtgatgat aaaaataatc
    11941 cgggaaaatt aactggtatc tctgaagatg tacagccgat cattctaccc gaaaagagtt
    12001 attatgaaat aaactttaat acagaagagg gaacctatac agtagaggct tattcgccgg
    12061 gaacaccaat tattgacgga cttaaaatgg gattcgttgg cggatggttt gatggcgcca
    12121 aaggctggga cggacctaag aatgtctatg aattgactca agatccggac aatccgcatt
    12181 gtctcactgc agaattgact tggagtaaac aagattcttt tgacgtgaca ataactccct
    12241 ataatgccaa tggcgattgg ctggagccag gttggcgttt tgacggtaaa aacgaatcat
    12301 ttgctactaa tacgaatgat tcatctaaaa aggtacccgc aggtaaatac acctttatat
    12361 ttgatacaca tcttgttcag tctaaattgc tgaagaaata attaaaataa tgccataaaa
    12421 acatgaaacg atatctattt ttattattat cgttctttgc gctgagcctt tatgctcagc
    12481 agggaagtct gactggtact gctattgcag ctagtgataa agaaccaatg attggtttga
    12541 ctgttctggt gaagggtact acaaatggta ctgtcacgga tctggatgga aactatacac
    12601 tgactaatgt tcctaaagat gcgactattg tattttccat gattgggtat aagacacaag
    12661 aagttaaagt caatggaaag aatgtcataa atgtagtcat ggaagatgat acacaagctt
    12721 tggatgaagt agttgttatc ggctatggtg cagtgaagaa gagtgacttg acaagctcta
    12781 tatctgctat caaaggagat gaactgaaaa agctgactgg cggtaatgcc atgaatgcct
    12841 tgcagggaaa gattaatggt gtgcagatta ccggtggtgg cggtccgggt acttcacctc
    12901 gtgttattat tcggggggta tctaccgtca atggttctga tccgttgtat gtcgttgatg
    12961 gaatgccggt gggaaccaat atcaattttc ttgaccagaa cgatattgaa tccatgcaag
    13021 tgctgaaaga tgcttcagca gcagctattt atggtacacg tggctctaac ggtgttgtcc
    13081 ttattactac caagaaaggt aaaaagggag ctacccaatt cggtttctct gcttctgccg
    13141 gttttcagac attgaagaaa ccggagatgg caaaagcttc cgaatacgaa tatgtgttca
    13201 aggcgcgtta tattaatgat aatgcagagc cccgttataa cagcaaggag aatatcacag
    13261 atgcggaagg tactgactgg tgggatgaaa gcatgaagaa gacagcactg attcataatt
    13321 ataattttaa tttctccgga ggtacggata agttgcttta ctctgccaat attggttatt
    13381 tcgggcaaga ctcacaatac actgtaggta actggcaaaa gctgacagcc cgtttcagta
    13441 tggaatacac ttttaataat atagtaaaag caggtattga ctttaccccg aaatatgaga
    13501 attggacaga tactcccagt ttattgggaa atataatggc tatggacccc acaactccga
    13561 tcatgcgtcc tcaaagtgaa tggacgacta atgaatacga caactatgcc cgttccagca
    13621 acaacttggt gtggaatccg gttgcccaat tagcccgtat ggataaacat agtgatgagt
    13681 atggtttatt agccaatccg tatgtaaaca ttgaaccgat taaaggcttg gttattcgtt
    13741 cacagtttgg tgtcaatgcc cgtttccgta tttcagatga gtttactcct tctttcaata
    13801 tcgatacatt agagaaatcc gattacagca aagcatatcg taaaaccgat aattgggtgg
    13861 actggaactg gacgaataca gtaaactgga ttaagagttt taatcataaa cacaatttga
    13921 atgtgatggc tggttatacg atggaacgtt tccaggaata ttggttggaa ggatcaaagg
    13981 aacgcactcc taccaatgaa gagaacctgc
//
