LOCUS       gnlProkkaIFOKHPHF_50   17089 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IFOKHPHF_50.
ACCESSION   gnlProkkaIFOKHPHF_50
VERSION     gnlProkkaIFOKHPHF_50
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:58:19
            Original ID  :: gnl|Prokka|IFOKHPHF_50
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17089
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17089
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[6282:7089]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6283..7089
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..17089
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17089
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             838..1581
                     /gene_functions="other (smcogs) SMCOG1250:DinB (Score:
                     157.6; E-value: 4.5e-48)"
                     /gene_kind="other"
                     /locus_tag="ctg48_1"
                     /transl_table=11
                     /translation="MALYGRLHRCVLDLVYQPCDSGPAVSDDRYERQAYDDRKQMLCSG
                     NVGSGRIFWGVTLLQLKEKRMKTTNFLEKEAMLMTDAKQFYDYHSWANKKIFNHIENLP
                     EKTAYQEVKSVFPSVSDVLLHMCRADYIWLNVLSGVAYQEIIDSAGKLESAHGNMAAIK
                     QLAADLESQYHDFFSRQTDLEQTFTMQHPKLGTLESTYADTILHVVNHGTYHRGNVTAM
                     LRQLGHSGVPTDYMYYLYEKRESKG"
     CDS             complement(1631..2683)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 214; E-value: 6.1e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_2"
                     /transl_table=11
                     /translation="MRKRRGWDVEHQVRCAVLGLGRLGYYHAKNLVTSVPGAKLVSVGD
                     PLKGRAEQVARELGIEKWSEDPYEVLEDPGIDAVIIVTPTSTHGDMIIKAAENGKQIFV
                     EKPLTLSLEESRAVSEKVKETGVICQVGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFT
                     RDQGAPPAAFIKHSGGIFIDCSIHDYDIARYLLGAEITSVSGHGRILNNPFMEQYGDVD
                     QALTYIEFDSGAAGDVEASRTSPYGHDIRAEVIGTEGSIFIGTLRNQHVTILSAKGSSF
                     DIIPDFQTRFHEAYCLELQHFAECVRNGKTPIVTDIDATINLEVGIAATNSFRSGRPVQ
                     LDVKRAYTGM"
     CDS             complement(2868..3881)
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 366.7; E-value: 1.9e-111)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg48_3"
                     /transl_table=11
                     /translation="MKTTIYDVAKAAGVSITTVSRVINNTGRISDKTRQKVMNVMNEMA
                     YAPNVYAAALTGKRTNMIALVAPDISNPFYGELAKSIEERADELGFQMLICSTDYDPKK
                     ETKYFSVLKQKKVDGIIFATGIESHDSMSALEEIASEQIPIAMISQDKPLLPMDIVVID
                     DVRGGYEAAKHLLSLGHTNIACIIGDGSTTGEKNRIKGFRQAMEEAGVPIDESLIIQTR
                     FSLESGKEEAGKLLDRNAPTAIFAFNDVLACAAIQAARIRGIKVPDELSIIGFDNTILA
                     EMAAPPLTTVAQPIKEMGRSVIELLAEAIEGKRKAKQKIVLPPELVVRHSTSPLNT"
     CDS             complement(3899..4762)
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 62.6; E-value: 5.4e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg48_4"
                     /transl_table=11
                     /translation="MPRILFTVPPFPVFIAAGEGVFKKGETHVKRVFSVFDLIYVKQGT
                     LYITENETSFSVEGGEYILLSPGLEHYGTKGSDEATSYYWLHFDEHRYEFTAKGGSNWS
                     ELQQEKGSFEEPARYGLALPRKGKVQRPQFMAQQFEKLIDYSAENSDLPLRKQILFEEL
                     MLHLQKEAFQIPSAKERVAWEAARYLQEHYKEKTTIKDLSLALHYHQDYVSRCMQQVLG
                     VTPAQYTNRVRMTEAKRLLSSTNDKMGVIAETVGMEDPTYFSKLFKQIEGISPIEYRKI
                     VSRKVQ"
     CDS             4886..6253
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 337.7; E-value: 1.5e-102)"
                     /gene_kind="transport"
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="MKQAVFKSTALKKPADKTFSLFSLTWPIFIEVSLYMFMGNADTLM
                     LSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTVIISQFLGSRQKKEAMEVAYVSIGA
                     NFFISLAISAVVFFAAVPLLHMMGLSNALMPDAKVFLQVVGGLSFIQALIMTFSAILKS
                     YGYTKDTMFVTIGMNILNIAGNFVVIFGLFGFPVLGVAGVAMSTSIARVIGLIAMIVIV
                     NKRIQLKMSLKKVFHMHKEHLRKLLKIGIPSAGEQLSYNLSQMIVTYFIAIMGAQALTT
                     KVYTQNITMFILLFGTAISQGTQILIGRYIGGKQFDAAYERCMKSLYWALGIAAATSVL
                     MTIFSKDLIGLFTQSPDIIATASLLIAMTIILEPGRSFNVIIINSLRAAGDAKFPVYMA
                     MISMWGIGLPLAYLFGIHLGFGLAGIWISFIADEWVRGILMYRRWRSRIWIQKGMA"
     CDS             complement(6283..7089)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_6"
                     /sec_met_domain="phytoene_synt (E-value: 9.6e-29, bitscore:
                     91.2, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEIKEAYQQCGQIVSAREPACYKAFSFLPLKQRQAAWAVMAFCH
                     TAANADEKALSAIEAEAEDVFSGTYNGNHFLWKAFGHAYQTFTLDSEPFREFIAAQKAE
                     DKPFGNLDELLMHAYQTGGAAWLMLLPIMARRHQKQLTHAAGSLGLAIQLIRILRDFGT
                     GQQQKSRIPREVMQQFGYTEDDLQKGVVNKAFTMTWEYIAFEAEAYLEECQDALPLFPQ
                     YSQKTVKATLHLHRAVLEKIRAKQHDVFQHHFALTETEVKQILSDI"
     CDS             complement(7194..8969)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 558.9; E-value: 2.4e-169)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_7"
                     /sec_met_domain="GATase_7 (E-value: 8.3e-49, bitscore:
                     155.5, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.2e-101, bitscore:
                     331.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTLSKRGPDDSNVWGEHHVLFGHKRLAVVDIEGGRQPMACTYK
                     GDTYTIIYNGELYNTEDLRKELRARGHQFERTSDTEVLLHSYIEWQEDCVDHLNGIFAF
                     AVWDEKRNLLFAARDRLGVKPFFYTKEGSSFLFGSEIKAILAHPDIKARVDRTGLSEIF
                     GLGPSRTPGTGVFKGIKEIRPAHALTFSKDGLNIWRYWNVESEKHTDSFDDTVANVRSL
                     FQDAVTRQLVSDVPVCTFLSGGLDSSAITAIAAGHFEKEGKAPLHTYSIDYEENDKFFQ
                     ASAFQPNDDGPWIEKMTEAFGTTHHKCVISQKDLVDHLEEAVLVKDLPGMADVDSSLLW
                     FCREIKKDFVVSLSGECADEIFGGYPWFHTADVESGFPWMRSTEERIKLLSDSWQKKLN
                     LKEYVNAKYEETLAETPLLDGETGVDKARRQLFYLNMLWFMTNLLDRKDRMSMGASLEV
                     RVPFADHRLVEYVWNIPWEMKMHDNREKGILRKALEGILPDDILYRKKSPYPKTHHPEY
                     TKGVSEWLKTIRSQKDSVLHTLLDRKQLDQLLETEGSSFKVPWFGQLMKGPQLIAHLAQ
                     IHTWFEAYRIDIDEG"
     CDS             9184..9765
                     /locus_tag="ctg48_8"
                     /transl_table=11
                     /translation="MKKKETACMKRKQLLYTEERKWEYGTILIEDGICLIENSEGDILL
                     ADSLQHSPIWIHYKGKWEQAGFQDKLVLACGAENISLSGGERIRYEKSVKRPLMALLDS
                     LDDETFLAFLQHLHSFGLSVFDCVFSYNKGVFSNTSEERGVSFYHFSNDTAQCAMQHHY
                     SSEGTGDRFEWTASNGKRSIMYSAVQRGRK"
     CDS             complement(9796..12480)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 241.4; E-value: 3.9e-73)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_9"
                     /sec_met_domain="Peptidase_S8 (E-value: 1e-48, bitscore:
                     156.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRRKFSSVVAAVLIFALIFSLFSPGTKAAAAGAIDQAAALENGK
                     EQTGAMKEPEQVKWYKVTPGATDIQKNSHMALTVKSDSVLNVSVYPSKEKALKDETFEM
                     YRSFTAEDGKSEVIFPYAWSGPYYVKVEYLGEEEPEDGGTAEAAAEAKYTIGYKGTKKQ
                     PSDLEEEEACPVEMSVDQKKSGKGILDKLRAIRDEQLSQTAEGKELTSLYYKAAPFIVA
                     KLALNKTARNEIYQDLVTLKPLFDDVSENGASSSYKITEKDQKAINRLYDKALQSVPSF
                     LKEEIKKQADRLNMKQLQGKTAGAILTENNIAAKSEIQTTKVIFKVKDNKSLSSVHNEM
                     KGFSASAQSKKDISNVKKAKKLFDNLYSFELPKDEKQNGAYTASAKRVKSAAATLSKMS
                     NVEFAEPVQEYKSLANDIQYPYQWPLKNNGENGGVKNADVKYEPANTLLSKRKLNDTLI
                     AVVDTGVDSTLADLKGKVRTDLGHNFVGRNNNAMDDQGHGTHVAGIIAAQSDNGYSMTG
                     LNAKEKIIPVKVLDSAGSGDTEQIALGIKYAADKGARVINLSLGGGYSRVLEFALKYAA
                     DKNVLIAAASGNDGENTLSYPASSKYVMSVGATNRMDMTADFSNYGKGLDISAPGSDIP
                     SLVPNGNVTYMSGTSMATPYAAAAAGLLFAQNPKLKRTEVEDMLKKTADDISFESVDGG
                     EEELYDDYGDPIEIPKTPGVDWHSGYGRLNVMKAVSAADLQLKVNKLESTQTAVRGNAK
                     EGTLIEVMNGKKKLGSAKAGKDNAFKVNIATQKQDQVLYVKATKGDAKTSYKVVVVKGK
                     PSGTPKVNAVKTKDTAVKGKANSKAVIRVKNKSKKVIASAKADAKGTFSVKIKKQKAGT
                     VLYVTAADTDKKESKEAKVVVEK"
     CDS             complement(13120..14025)
                     /locus_tag="ctg48_10"
                     /transl_table=11
                     /translation="MKFATGELYNRMFVGLIIDDEKIMDLQKAEKKLFELETIPGSLIE
                     CIAEGDKFVAHARQLAEWAKKPNDELGSFMYSLSEVKLHAPILKPSKNIICIGKNYRDH
                     AIEMGSEADIPEHPMVFTKSPVTVTGHGDIVKSHEEVTSQLDYEGELAVVIGKSGTRIS
                     KEDAYDHVFGYTIVNDITARDLQKRHKQFFIGKSLDTTCPMGPVLVHKSSIQEPGRLKV
                     ETRVNGELRQSGSASDMIFSIPELIETLSKGMTLEAGDIIATGTPSGVGNGFTPPKFLR
                     SGDKIDITIDPIGTLSNQIG"
     CDS             14180..15103
                     /locus_tag="ctg48_11"
                     /transl_table=11
                     /translation="MERVHLFFHREQLKRKGTAKGLFITDRSVSPILLTQRDRAEKASY
                     EISWEKSLLGERTLFLNAEQDDPSLMRRRLAYCFFDQIGVPAPAATYSFLTINGQPEGI
                     YLNIKNHQPAGKTSYGVKTADPRVPLSLFNNDSSAFLHEFFILIRTAGDDELAERIKLY
                     LDVKLFFLWLIGNACTNQGFYYTFCLNESGRLYISPIESRSLAVQEWHDEDPLLTKGKT
                     LSSRLLSIPAFRSQYHTLMKNVLKRSFTIERLSPLINEWHLDICQSATDDPFIKKSPFQ
                     IEKEQTNILREIEERQDFLQAHLARL"
     CDS             15249..15419
                     /locus_tag="ctg48_12"
                     /transl_table=11
                     /translation="MNSKIEEMRITLIETAQKYGMNSKETIQCSQELDILLNTRIKEEM
                     IFGRYLENARM"
     CDS             16335..16952
                     /locus_tag="ctg48_13"
                     /transl_table=11
                     /translation="MYDQSVSSYLQNLNSFVQQQAIHIQQLERQLKEIQTEMNTMKQRP
                     ATTIERVEYKFDQLKIERLDGTLNIGLNPTDPNSVQNFEVSQSTPQIGMMQQEESAQLM
                     QQIRQNVDMYLTEEIPDILEQLENQYDSRLDDTNRHHVIEDIRKQMDSRIHYYMSHIKK
                     EENTPPAQYAEHIAEHVKRDVIRAVEHFLEHIPSEMKGDEQA"
ORIGIN
        1 gtcaattagt tttttggttt gtttgatccg gtttttctta cgctcttcaa catccgaatt
       61 aaattgagtc ttaactttct tcccttttgt ttcagcattc ttataacaaa agctcgtgaa
      121 tctttatatt agactggata atgattcacg tagagagcca tacctctacg gcgataggcg
      181 ttagataatt tacctctttc ttctattgta tttgtcgata ttgcatcagc atacaccacg
      241 catttcattt ttaaggttaa atcgtttttt cgcagcttgt gttccctgtt gttggctttc
      301 tcatattatt cttcggatat gattttagga cacatgtctt tgtaaatggt ccacttttct
      361 ttcgggtttc taatgaattt ttcgcctgct ttaacatgtg tttgcctgtt cgcagtaaaa
      421 acaccgcagt aaatggggtt ctttaagatt gtttgcacag tagacagttt ccaaaaatac
      481 gcctttcttg gcttcagaat attcccgagt gctagttctt cattaagttt gagtcatcag
      541 tgcttcagtc tgcgataccc ttctcattgt attggctgtt gcgggcgtat ctgtcatcgt
      601 gcagcagctg cctgtgtttg agacagtcat gatggccggc ggctttttat ttttgctcta
      661 tatgggctgg gtgaattgga acagccgtcc gaacacaagc caaaatgaga aacatacgtt
      721 cacaccaaaa aagcaagctg catttgctgc cgctgtttct cttttaaacc cgcatgccat
      781 tctggacacg atcggcgtca tcggcacgag ctctcttcaa tattcggggc ttgagaaatg
      841 gctctttatg gccgcctgca tcgctgtgtc ttggatttgg tttatcagcc ttgcgatagc
      901 gggccggctg tttcagacga tagatacgag cggcaggctt atgatgatcg taaacaaatg
      961 ctctgcagcg gtaatgtggg cagcggcagg atattttggg gtgtcactct tttgcaattg
     1021 aaggagaaac gaatgaaaac aacgaatttc ttagaaaagg aggcaatgct gatgactgat
     1081 gcaaaacagt tttatgacta tcattcttgg gcaaacaaga aaatatttaa ccatatcgaa
     1141 aacctgccgg agaaaactgc ctatcaagaa gtaaagagcg tatttccttc tgtcagcgac
     1201 gtgctgcttc atatgtgcag ggctgactac atttggctga atgttctttc gggagtggcc
     1261 taccaagaga ttatagacag cgcaggcaaa ttagagtccg cgcatggtaa tatggcagcg
     1321 attaaacagc tcgctgccga tctggagtca cagtatcatg atttcttcag ccgccagacg
     1381 gacttagaac agactttcac aatgcagcat ccgaaactcg gtacactgga atcaacctat
     1441 gcagacacca tcctgcatgt cgtcaatcac ggcacttacc acagagggaa cgtaaccgcc
     1501 atgctgagac agctgggcca ttcaggcgta cctactgatt atatgtacta tttatatgag
     1561 aaaagagaaa gcaagggcta aaatgtcctt gctttttttg cggaaagcct caaatgcaac
     1621 atattagctt ttacatacct gtataagcgc gcttcacatc tagctgtacc ggcctgccgc
     1681 ttcgaaagga attggttgcg gcgataccca cttctaaatt gatcgtcgca tcaatatcag
     1741 tcacaatcgg tgtttttcca ttccggacac actcggcgaa atgctgaagc tccaagcagt
     1801 aggcttcatg aaaacgagtt tgaaagtctg gaatgatatc aaaactgctc cctttagccg
     1861 ataggatggt cacatgttga tttctcaatg tccctatgaa aatactgccc tctgtcccga
     1921 tcacctccgc ccggatgtca tgtccgtatg gagaggttct gcttgcctcg acgtcccccg
     1981 ctgcgccgga gtcaaattca atatacgtca gcgcctgatc cacatcgcca tactgctcca
     2041 taaacggatt gttcagaatc ctgccgtgtc ctgaaacaga agtgatttcc gcccctagca
     2101 aataacgggc aatatcatag tcatggatgg aacagtcaat aaaaattcca ccgctgtgtt
     2161 tgataaatgc tgcgggaggc gcgccttggt cgcgcgtaaa gcctttataa tagataggtt
     2221 tgccgatttc tccagcgtcg atccgccgtt tggcatctgc gtatgctgga tcgaaccgtc
     2281 tcataaagcc gacttggcag atgacacctg tctctttcac tttttcagaa actgctcttg
     2341 attcctcaag gcttaatgtc agcggttttt caacgaagat ctgtttgccg ttctcggctg
     2401 ctttgatgat catatcacca tgtgtgcttg tcggcgttac gataatgaca gcatcaatgc
     2461 cgggatcttc taacacttca tacgggtcct ctgaccattt ttcaataccg agttctctgg
     2521 caacctgctc cgctctccct tttaacggat caccgacact aaccagcttt gcccccggca
     2581 cactggtgac gagatttttc gcatgataat aaccgagcct tcctaatccc aatactgcgc
     2641 accttacttg atgttccacg tcccatcctc tcctttttct catttcaggc tcgctttgag
     2701 aaagcgcttt ctcttaacag ctaaaaaaac agcggttcta tccgctctgc cattttgcgc
     2761 aagcgctttc tcaaaagatg gttttatttt acactgcctt tggtttacac gcaatatgtt
     2821 tttttggctt caactgtcat aatgaaaaaa cccgctcatt agcgggctca tgtgttgagc
     2881 ggtgatgtag aatgtctgac tacaagctca ggcgggagca ctattttttg tttcgccttt
     2941 cgttttccct ctattgcttc tgccagcagt tcgatgacgc tccgccccat ctcttttatc
     3001 ggctgggcta cggttgtcag gggcggagcc gccatttctg cgagtatcgt attatcaaaa
     3061 ccaatgatag aaagttcatc cggcactttt atgcctctta ttctcgcagc ttgtatggcg
     3121 gcacaagcca atacgtcgtt gaaggcaaaa atagcagtcg gagcgttcct gtcgagcaat
     3181 tttcccgctt cttccttgcc gctttccaag gaaaaccgcg tctggatgat aagtgattca
     3241 tcaatgggca cgcccgcttc ctccatcgcc tgacggaagc ctttgattct atttttttcg
     3301 cctgtcgttg acccgtctcc gataatgcag gcgatgttcg tgtggccgag tgacagaaga
     3361 tgcttggcag cctcatatcc gccacgaacg tcatctatca caacaatatc catcggaaga
     3421 agcggcttat cctgagaaat catggcaatc ggaatttgtt cactggcgat ttcctccaaa
     3481 gcagacatac tgtcatggct ttcaatccct gttgcaaaaa taatgccatc cacctttttc
     3541 tgtttcagca cagaaaaata ttttgtttct tttttcgggt cgtaatcggt gctgcaaatc
     3601 aacatttgaa aaccgagctc atccgctctt tcctcaatgc ttttggccaa ttcgccgtaa
     3661 aacggatttg aaatatcagg cgccacgaga gcaatcatat tcgttcgttt tcccgttaac
     3721 gccgcggcgt agacattggg cgcgtatgcc atttcattca tgacattcat gaccttctgc
     3781 cgtgttttat cgctgattct ccccgtattg tttatcacac gggacacagt tgtgatcgag
     3841 acacccgccg cctttgccac atcgtaaatt gttgttttca tgttcatccc tcgtctggtt
     3901 attgaacttt ccggctgaca attttccggt attcaattgg tgaaatgcct tctatctgct
     3961 taaagagttt tgaaaagtat gtcggatctt ccattccgac cgtttccgca ataacgccca
     4021 ttttatcatt tgtagaggat aaaagacgct tcgcttccgt cattctcacc cggttcgtgt
     4081 attgtgccgg agttacgccg agcacctgct gcatgcagcg gctcacataa tcctgatgat
     4141 agtgaagggc gagcgacagg tccttgattg tcgtcttttc cttatagtgc tcctgtaagt
     4201 accgggccgc ctcccaggct acccgctctt tcgcagacgg tatttggaac gcttcttttt
     4261 gaagatgcag catcagctcc tcaaataaaa tttgctttct gagcggcaaa tcagagtttt
     4321 ccgcggagta atcgatcagc ttttcaaact gctgcgccat aaactgcggg cgctgcacct
     4381 tgccttttct cggcaaggcc aatccgtagc gggccggctc ttcgaagctc cctttttcct
     4441 gctgaagctc agaccagttg ctgcctccct ttgccgtaaa ttcatatcga tgttcatcga
     4501 agtgaagcca atagtaggag gttgcttcat cactgccctt cgtcccgtag tgttcaagac
     4561 cgggagaaag caagatgtac tcgccgcctt caacagaaaa cgatgtctca ttttccgtta
     4621 tatataacgt tccctgtttg acatatatca gatcaaacac ggagaataca cgtttcacat
     4681 gggtttctcc ttttttaaac accccttccc cagctgcgat aaataccgga aaaggcggga
     4741 ctgtaaacag gatgcgaggc atttgaatca tcctcctttt taagtcggat ttttacaaga
     4801 agtatcgttt ctatcccttt ttattataag gaaatggagg tacactttaa aacgttgatt
     4861 ttatttacga aaggggttag acactatgaa acaagctgtc ttcaaatcaa ctgctttgaa
     4921 aaaacccgct gacaaaacgt tctcattatt ttcgcttact tggccgatct ttattgaggt
     4981 ctcattatat atgtttatgg gtaatgccga tacactgatg ctcagccaat actcggataa
     5041 cagcgtggca gcagtcggcg tcagcaacca gattttaaat ttaattatcg tgatgttcag
     5101 ctttatcgca acaggaacga ccgttatcat ttcacaattt ctaggctcac ggcaaaagaa
     5161 agaagccatg gaagtcgctt atgtgtcaat cggcgccaac ttcttcatca gcctggccat
     5221 cagcgccgtc gtctttttcg cggctgtccc tctgcttcat atgatgggat tatcaaacgc
     5281 actgatgcct gatgcgaaag tctttttaca agttgtcgga ggtctgtcct ttattcaggc
     5341 tttaatcatg acattcagcg cgatcttaaa aagctacggc tacacaaaag atacaatgtt
     5401 tgtcactatc ggcatgaaca ttttaaacat tgccggaaac tttgttgtga ttttcggttt
     5461 gttcggcttt cctgttctcg gcgttgccgg tgtggccatg tccacatcta tcgcccgcgt
     5521 catcggatta atcgcgatga ttgtgattgt caacaaacgc atccagctga agatgtcgct
     5581 gaaaaaagtc tttcatatgc ataaagagca tttgcgcaag ctgctgaaaa tcggcattcc
     5641 ttctgcggga gagcagcttt catacaacct ttcgcaaatg attgtcacgt attttatcgc
     5701 gatcatgggc gcgcaggcgt tgacaacaaa agtgtatacg caaaatatta cgatgtttat
     5761 tttgctgttc ggcactgcga tcagccaggg tacacaaatc ttaatcggcc gttatatcgg
     5821 cggcaaacaa tttgatgccg cttatgagcg ctgcatgaag agcttatatt gggcactcgg
     5881 aattgctgcg gctacctctg ttttgatgac gatcttttca aaagacctga tcggactctt
     5941 cacacaaagc cctgacatta tagcaactgc aagcctattg attgccatga ccattatcct
     6001 tgaaccaggc cgctcgttta atgtcattat cattaactct ctgcgggccg cgggggatgc
     6061 gaaattcccg gtttacatgg caatgatttc aatgtggggc attggcctcc cgcttgctta
     6121 tcttttcggc atccacctcg gtttcggtct tgccggcatt tggatttctt ttatcgcgga
     6181 tgaatgggtc cggggaatct taatgtacag aagatggcgc tcacgtatct ggatacaaaa
     6241 aggtatggcg taacacccgg ctcaatcaag gccgggtgtt ttttagatat cagagagaat
     6301 ctgcttcact tcggtctctg tgagagcgaa gtgatgttga aatacatcgt gctgcttcgc
     6361 ccggattttt tctaaaacag cccggtgcaa atgaagagtg gctttcaccg ttttttgaga
     6421 atactgcgga aatagcggca aggcatcctg acactcttca aggtaggctt ctgcttcaaa
     6481 agcgatatac tcccacgtca ttgtgaacgc cttattcacg acgccctttt gaaggtcgtc
     6541 ctctgtatat ccaaattgct gcatcacttc ccgagggata cggctctttt gctgctggcc
     6601 agtgccgaaa tctctcagaa tccgaatcag ctgaatcgct aaaccgagag aaccggctgc
     6661 atgtgtcagc tgtttctgat gccggcgcgc cataatcggg agcagcatca accaggctgc
     6721 gccgcctgtc tggtatgcgt gcatgagcaa ttcatcaagg tttccaaacg gtttatcttc
     6781 cgctttctgt gcggcaatga actcacggaa tggctcgctg tccagtgtaa aggtttggta
     6841 cgcatggccg aaagccttcc acaaaaagtg attcccgtta tacgtaccgg aaaaaacatc
     6901 ttccgcctca gcttcaatgg cagataacgc cttctcgtcc gcattggctg ccgtatggca
     6961 aaacgccatc accgcccaag ctgcctgcct ttgcttcagc ggaagaaacg aaaatgcttt
     7021 gtaacaggct ggttcgcggg cgctgacgat ctggccgcat tgctgatagg cttcttttat
     7081 ctctttcatt tcttttcact cctatgtatc actgcttctt caagtctatt atgttttctc
     7141 gcaattgtat atgaagaaaa agccgattcc tttgagcaga atcggctttt tctttatcct
     7201 tcatcaatat caatgcgata cgcttcaaac catgtatgaa tttgagcaag atgggcgatc
     7261 agctgaggcc ccttcatgag ctgcccgaac cacggcacct tgaaggagga gccttccgtt
     7321 tctaaaagct gatctaattg ttttctgtcc agcaaggtat ggagcacgga gtccttttgg
     7381 cttctgatcg ttttcagcca ttcgctgacg ccttttgtat attccggatg gtgtgttttc
     7441 ggatacgggc tttttttgcg atacagaatg tcatcaggca aaataccttc aagcgctttg
     7501 cgtaaaatgc ctttttcccg attatcatgc attttcattt cccacggaat attccaaaca
     7561 tattccacaa gccggtgatc ggcaaacggc acccgcactt ccaggctcgc ccccatgctc
     7621 atgcgatcct tccgatccaa aaggttcgtc ataaaccaaa gcatatttaa atagaacagc
     7681 tgtcttcttg ctttatccac acccgtttcc ccgtctaata atggcgtttc tgccaaggtt
     7741 tcttcatatt tggcatttac gtattctttc agattcaatt ttttctgcca tgaatcagaa
     7801 agcagcttga tccgctcctc cgttgatctc atccatggaa agccagactc aacatctgcc
     7861 gtatggaacc acgggtaccc gccgaaaatc tcatccgcgc actctcccga taggctgacg
     7921 acaaagtcct ttttgatttc ccggcaaaac cacagcaggg atgagtcgac atccgccatt
     7981 cccggcaagt ctttgaccag tacagcttcc tccaaatgat caacgagatc tttttggctg
     8041 atgacgcatt tgtggtgcgt tgttccgaaa gcctctgtca ttttttcaat ccatggtccg
     8101 tcatcgttcg gctgaaaagc gcttgcttga aaaaatttat cgttctcttc gtaatcaatc
     8161 gaataagtat gaagcggtgc ttttccttcc ttttcaaaat ggcccgccgc aatcgctgta
     8221 attgcgcttg agtccagacc gcctgatagg aatgtgcaaa ccggcacatc cgacacaagc
     8281 tgccgcgtca ccgcgtcctg aaataacgat ctgacattgg caaccgtgtc atcaaaactg
     8341 tccgtatgtt tttcgctttc aacattccaa taacgccaaa tattaagtcc gtccttggaa
     8401 aatgtcagcg cgtgagccgg gcggatttct tttatgcctt taaatacgcc agtgcccggg
     8461 gttctggacg gtccaagacc gaaaatttca gaaagtcccg ttctgtccac tcgcgctttt
     8521 atatcagggt gcgcgaggat tgctttgatt tccgacccga agagaaatga agagccttcc
     8581 ttcgtgtaaa aaaacggctt tacgccgaga cggtctctcg cggcaaacag cagattacgc
     8641 ttttcatccc acacagcgaa agcaaatatg ccattgagat ggtcgacaca gtcttcctgc
     8701 cattcaatgt agctgtgcag aagcacctcg gtatctgacg tacgctcgaa ttgatggcca
     8761 cgcgcccgca attctttgcg caaatcttcc gtgttataaa gctcgccatt gtaaataatg
     8821 gtgtacgtat ctcctttata ggtacacgcc atcggctggc gtccgccttc aatatcaaca
     8881 accgcaagtc ttttatgtcc gaataaaaca tggtgctccc cccaaacgtt tgaatcatca
     8941 ggccctcgtt tggaaagagt gtctgtcatt ctgtccatcg tttgtttttc ctggacgagc
     9001 tgctttttaa aatcgaccca acccgtaatt ccacacatgt gacatcagct ccaatcccgt
     9061 ttctttcgta acaatttcgt ttctttcagc accttagtaa gtttatgcat ctataggcag
     9121 atagttgatt tgtccataaa agagttgtat gggacaggct tgaattggaa agaaaagaga
     9181 ggaatgaaga aaaaggagac agcatgtatg aaacggaaac aattgttata tacagaggaa
     9241 cgaaagtggg aatacggcac catcctcatt gaagacggca tctgcttaat cgaaaacagt
     9301 gaaggcgata tactgctggc ggacagtctc caacacagcc caatctggat ccattataaa
     9361 ggaaagtggg agcaagccgg ctttcaggac aagttggttt tggcatgcgg tgcagaaaac
     9421 atctcccttt ccgggggaga acgcatccgc tatgagaaat cagtcaagcg gccgctcatg
     9481 gcgcttttgg attcgcttga cgacgaaacc tttctcgcat ttctacagca cttgcacagc
     9541 ttcggcttat cggtatttga ttgcgtcttt tcttataata aaggagtctt ttcgaatact
     9601 tcggaggagc ggggtgtgtc cttttatcac ttttcaaatg acaccgcaca atgcgcgatg
     9661 cagcatcact acagcagcga agggacagga gaccgttttg aatggacggc ttcaaacgga
     9721 aagcgatcca ttatgtattc agcagtccaa cgggggcgca aataaaaaag cggtgcatcg
     9781 agcaccgctt tttggttact tttcaacaac aacttttgct tccttgcttt cttttttatc
     9841 tgtatccgca gccgtgacgt acagcaccgt tccggctttt tgttttttga ttttcaccga
     9901 aaacgttcct tttgcgtcag ctttggcaga agcaatgact ttctttgatt tgtttttcac
     9961 tctaatcacc gctttgctgt tcgccttccc ttttactgcc gtatccttcg ttttcaccgc
    10021 gtttactttc ggtgtgccgg aaggttttcc tttgacgaca acaactttat acgatgtttt
    10081 cgcatcgcct tttgttgctt tcacatacag tacttgatcc tgtttttgag tcgcgatatt
    10141 aaccttgaac gcattgtctt ttccggcttt ggcactgccg agtttctttt tgccgttcat
    10201 cacctcgatc agtgtgcctt ccttcgcgtt tcctctgaca gctgtttgag tgctttccag
    10261 cttgttgacc ttgagctgta aatcagctgc gctgacagcc ttcatgacat tcagccgccc
    10321 gtagcctgaa tgccagtcta caccaggtgt cttcggaatt tcaatcggat cgccataatc
    10381 gtcatacaac tcttcttctc cgccatcgac actttcaaag gaaatatcat ctgccgtctt
    10441 tttcaacata tcctcaactt ctgttctttt cagcttagga ttttgagcaa acagcaatcc
    10501 tgcagcagcg gcagcatacg gcgtcgccat agacgttccg ctcatgtacg tgacatttcc
    10561 gttcggcact aagctcggga tatccgaccc tggagcagag atgtccagac cttttccata
    10621 gttagagaaa tcagcggtca tatccatgcg gttcgttgcg ccgactgaca tcacatattt
    10681 agaagatgca ggataagata aggtattttc tccatcattc ccgctggctg cggcaatcaa
    10741 gacatttttg tcagctgcgt acttcaaagc aaattcaagc acgcggctgt agcctccacc
    10801 taaacttaaa ttaatcaccc ttgctccttt gtcagcagca tatttgatgc cgagagcaat
    10861 ttgttcagta tctccggaac ctgcggaatc aagcactttt acagggatga ttttttcttt
    10921 ggcattcaat ccagtcattg aatagccgtt atcgctttgg gccgcaataa tgcctgcgac
    10981 atgcgttcca tgcccctgat catccattgc attgttattc cgtccaacaa aattgtgtcc
    11041 gagatctgtt cttacttttc cttttaaatc ggcaagcgtg ctgtctacgc ctgtgtctac
    11101 tactgcaatg agtgtatcgt taagcttgcg tttggacagc aatgtgttgg caggctcata
    11161 tttcacatct gcatttttga caccgccgtt ttcaccgttg tttttaagcg gccattgata
    11221 agggtactga atatcgtttg ccaggctttt gtattcctgc acgggttccg caaactctac
    11281 attggacatc ttggatagtg tcgcagcagc gcttttgacc cttttggcgc ttgccgtata
    11341 tgcgccgttc tgtttctcgt ctttcggaag ttcaaatgaa tacagattgt caaacagttt
    11401 cttagccttt ttcacattag aaatgtcttt tttcgattgc gcgcttgcag aaaagccctt
    11461 catttcatta tgtacggatg agaggctttt attgtccttc accttgaaaa taacctttgt
    11521 tgtctgaatt tcactttttg ctgcaatatt gttttctgtt aaaatggcac ctgctgtttt
    11581 gccttgcagc tgcttcatat ttagtcggtc cgcttgtttc tttatctcct ctttaaggaa
    11641 tgacgggact gattgtaaag ctttatcata tagccggttg atcgcttttt gatccttttc
    11701 agtgatctta tacgaagatg atgctccgtt ttctgacaca tcgtcaaata acggctttaa
    11761 tgtcacaaga tcctgataga tttcatttct tgctgtttta ttgagtgcga gttttgcaac
    11821 gataaacggt gctgctttgt aataaaggct tgtcagttct ttgccttctg ctgtttggct
    11881 cagctgctca tcacgaatcg ctctcaactt atccaggatg ccttttcctg atttcttctg
    11941 atcgacactc atttcaaccg gacaagcttc ttcctcttct aaatctgacg gctgtttttt
    12001 ggtgccttta tacccaatcg tatacttggc ttctgcagct gcttctgccg ttccgccgtc
    12061 ctctggctct tcttctccga ggtattcaac ttttacatag taagggccgc tccacgcgta
    12121 tggaaaaatg acttcgcttt ttccatcctc cgctgtgaaa gaacggtaca tctcaaacgt
    12181 ctcatcttta agcgcttttt ccttacttgg atatacagat acattcagta ctgaatcact
    12241 ctttacggtc agtgccatat gtgagttttt ctgaatatcc gttgctcccg gggtcacttt
    12301 gtaccatttc acctgttccg gctccttcat ggcgcctgtc tgctctttgc cgttttccag
    12361 agcagccgcc tgatcgatcg cgccggccgc tgcagctttg gttcccggag aaaaaaggct
    12421 gaaaatcagt gcaaaaataa gcactgccgc cacaaccgag ctgaattttc tgcgtttcat
    12481 gttatccctc ctgcaaaata atgaatctcc ttgaaggtat catgatttca taggacgaga
    12541 taccgcttac agggaatttt aaggttattt taaatgattt ggaatatgag gggataaata
    12601 taaaaaaacc caactctatc aaagagccgg gttcataggt ttttctatta aaacaattga
    12661 aaaccgattg gcaaatgcag accgagcagc actgtcagca aaaggacaat gacgaagccg
    12721 acccacaggc ctcctgttga tttttctttt ttcttgcgga tgaggagcat ttccatcagg
    12781 ccgatggtga taatgcccag aatcattttg ccggcgtatt ctccgttcca gttggcgaaa
    12841 cggacaaaca gctcagctcc tgtcaaaata ataaggatat agaataaccg cagaatcata
    12901 tgagtgattt ttgcgccctt tgcacttcct gacgaataca gcgagtagct gacgaaaagc
    12961 agaatcagcg ctaccaccca tgtcgtaata tgtaggtgtg tcatatatgt tccccctatc
    13021 agataaatta ccccacttat agtaccatga acttgtcctc tgccacaaag atgattatca
    13081 gaaaaaacgg gcgggtccgg gtccgccctc cagttttatt cagccaattt ggtttgacag
    13141 cgttccgatc ggatcaattg taatatcaat tttgtcacct gaccgcaaga attttggagg
    13201 cgtaaaccca ttgccgacac cagacggcgt accggtggca ataatgtcgc ccgcttcaag
    13261 cgtcatcccc tttgagaggg tttcaattaa ttccggaatg gaaaagatca tatcgcttgc
    13321 cgaaccggac tggcgcagct cgccgttgac tcttgtttca accttgaggc gccctggctc
    13381 ctgaatagat gatttatgta caagcacggg ccccatcgga catgtcgtat ccaagctttt
    13441 tccgataaaa aactgcttat gccttttttg cagatcacgc gccgtgatat cattcacaat
    13501 cgtatatccg aaaacatggt catatgcatc ttcttttgaa atgcgggtcc cgctttttcc
    13561 gatcacgaca gcaagttctc cctcataatc aagctgagag gtaacctctt catggctctt
    13621 tacgatatca ccatgccccg taaccgttac cggcgatttt gtaaatacca tcggatgctc
    13681 cggaatatca gcctcgctcc ccatttcaat cgcgtgatcc cggtagtttt tgccgatgca
    13741 gatgatattt tttgatggct tcagaatggg tgcatggagc ttcacctcag ataatgaata
    13801 cataaatgat cccagctcat cattcggttt ctttgcccac tcggccagct gccttgcatg
    13861 cgcaacgaat ttatcccctt ctgcgataca ttcaatcagc gatcccggaa tcgtctcaag
    13921 ttcaaacagt tttttttcag ccttctgcaa atccataatt ttctcatcgt caatgatcag
    13981 gccgacaaac attcggttgt aaagttcccc tgtcgcaaat ttcatgttat tcctccatca
    14041 tcttttaaat cagaatgctc cttcatgtat tctctgtcga atgctgaaat ccctttttct
    14101 caattccgtt ttcatttcgt ttcaggacgg gcttgctcta catatcatac aaatgtcgtt
    14161 ttgagaagga ggaaagaata tggagcgcgt gcatttattt tttcatcggg agcagctgaa
    14221 aaggaaaggt actgccaagg ggcttttcat aacagatcga tctgtttctc ccattcttct
    14281 cacacagcgt gacagagcgg aaaaggcatc ctatgaaatc agctgggaaa agtctctgct
    14341 tggtgaaagg acactttttt tgaatgcgga acaggatgat ccgtccctga tgcggcgcag
    14401 actcgcctat tgtttttttg accagatcgg cgtacctgct cccgctgcca cgtacagctt
    14461 tctgaccatc aatggccagc ctgaaggcat ttatttgaac atcaagaacc atcagccagc
    14521 cggtaaaacg agttacggag tgaagacggc cgatccaagg gttccgttgt ccctttttaa
    14581 caatgattcc tcggcattct tacatgaatt tttcatactg atccgcacag ccggagatga
    14641 cgaattggct gaacgcatta aattgtacct ggatgtcaag ctgttttttt tgtggctgat
    14701 cggcaacgcc tgcaccaatc aaggctttta ctacacattt tgtttaaacg aatccggcag
    14761 gctttacatt tctccgatag agtcaagatc gcttgccgta caagaatggc atgacgaaga
    14821 cccgcttctg acaaaaggaa agacgctttc ctcaagactt ctatccattc ccgccttccg
    14881 gtcgcaatat cacaccttaa tgaaaaacgt gctgaagcgg tcgtttacta ttgaacgatt
    14941 atctcctctc atcaacgaat ggcaccttga catttgtcaa agtgctactg atgatccttt
    15001 tatcaaaaaa agcccctttc agatcgaaaa ggagcagaca aacatactta gagaaattga
    15061 ggaacggcag gactttttgc aagcacactt agcaagactt tagtcctttc tccattcaaa
    15121 aaggccgcag caaaaattgt cgctttttta gtcaaattga cgaaaggcaa ccttttgagc
    15181 caaaataggt tatactaacg atatcctgta tttatatcaa aataaaatct agaattggag
    15241 atagcgtaat gaacagtaaa attgaagaaa tgaggatcac actaattgaa accgcacaaa
    15301 aatacggcat gaattcaaaa gaaacgattc aatgcagcca agagctggat atcctgctga
    15361 atacccggat taaagaagaa atgatttttg ggagatatct tgaaaacgcc cgtatgtaaa
    15421 tcattttcta taacaattag aatacaccac atgtaactcc gctttttgct cagcacttct
    15481 gggatatacc tcagggcgag aatatgcccg cccaaaaatc gaataccgca gcaagacata
    15541 ctccaaaaag catttctaca cgcaaaaaca ccaaagaaat gaacaaaaat caccataggc
    15601 ggatagcggc atccttcgcc gcatttccgc tcaatttata cccaacatcc tctttttcca
    15661 tgtttaaaca taacggcccg aaagaataaa acgctttcat caagagccct tatgtcccct
    15721 ttaaatttct ctcacacata tgtgcgtttg tcataagcta tcgtgaatag cccaattgaa
    15781 atcagaattg tcatttcact ttacctgtct ttttttaatt tttcaacaaa ggatgtgctc
    15841 gtatgccggc cattgtcgga gcgtttaaaa ttaatgcgat tggtacgagc ggagtcgttc
    15901 acatcgggga ctgcattacg atttctcctc aggctcaggt cagaacgttt gccggtgccg
    15961 gcagctttaa taccggcgac agcctcaagg tgatgaatta tcaaaacgcg acgaatgtgt
    16021 atgacaatga tgcggttgat cagccgatcg tggccaatgc gtaaaaggag tgaggctcat
    16081 gaacttctat attaatcaaa ccattcaaat caactatctc cggctggaat caatcagcaa
    16141 ctcctccatt ctgcaaatcg ggagcgccgg atcaatcaag tctctgtcaa atttgtataa
    16201 tacagggagt tatgtagaac cggcaccaga agtttctggc tcagggcaac cgctccagct
    16261 gcaggagccc gacacaggtt cattggtccc gctccagcct cctggccgtt aatcatatga
    16321 aagaggtgaa gaacatgtat gatcaatctg tttcctctta cctgcaaaac ttgaattcct
    16381 tcgttcagca gcaggcgatt cacattcagc agctcgaacg tcagctgaaa gagattcaaa
    16441 ctgaaatgaa tacgatgaaa cagcggccgg ccactaccat tgagcgtgtg gagtataaat
    16501 ttgatcagct gaaaattgaa aggctcgacg ggactttgaa catcggctta aatccgactg
    16561 acccgaacag cgtccaaaac tttgaagtca gccagtcgac accgcaaatc gggatgatgc
    16621 agcaggaaga gagcgctcag ctcatgcagc agatccggca gaatgtcgac atgtacttaa
    16681 ccgaggaaat cccagatatt ttggaacagc ttgaaaacca atatgacagc agacttgatg
    16741 atacaaacag acatcatgtc attgaagaca tcagaaaaca aatggacagc cggattcact
    16801 attatatgtc ccatatcaaa aaagaagaaa atacaccgcc tgcacaatat gcagaacata
    16861 tcgctgagca tgtgaagcgt gatgtcatcc gcgctgtaga acactttctg gagcatattc
    16921 catcagaaat gaaaggagat gagcaagcat gatctttaca gtcatcaacc gcagcttgga
    16981 agtcggggac atccggatga acggtgtgtc cagttcctcc gttttccaca tcggagacac
    17041 tgaatccatt tacctgtctt ctatttttga tacaccgcct gaatctctt
//
