LOCUS       gnlProkkaLCAHIECF_4    28125 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LCAHIECF_4.
ACCESSION   gnlProkkaLCAHIECF_4
VERSION     gnlProkkaLCAHIECF_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 15:19:46
            Original ID  :: gnl|Prokka|LCAHIECF_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 28125
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..28125
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[561:8125]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      562..8125
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..28125
                     /SMILES="NC(Cc1ccc(O)cc1)C(=O)NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="betalactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..28125
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="betalactone"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     protocluster    1..26140
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4306:16140]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      4307..16140
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
     CDS             3..548
                     /NRPS_PKS="Domain: Condensation_LCL (6-148). E-value:
                     2e-50. Score: 163.4. Matches aSDomain:
                     nrpspksdomains_ctg4_1_Condensation_LCL.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="Condensation (E-value: 1.1e-44, bitscore:
                     147.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVLGARTEQEAAAAFIKPFDLSQAPLFRAQIVKVSNERHLLLV
                     DMHHIISDGVSVNILIREFGELYNNRNLPALRIQYKDYAVWQEGFKTGDAYKTQEAYWL
                     KQLEGELPVLDLPADHARPPVRSFAGDKVSFTLDPEVASGLHKXXXXXXXXXXXXXXXX
                     XXXXXXXXANCRPAAQGS"
     aSDomain        21..446
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.00E-50"
                     /label="ctg4_1_Condensation_LCL.1"
                     /locus_tag="ctg4_1"
                     /protein_end="148"
                     /protein_start="6"
                     /score="163.4"
                     /tool="antismash"
                     /translation="ARTEQEAAAAFIKPFDLSQAPLFRAQIVKVSNERHLLLVDMHHII
                     SDGVSVNILIREFGELYNNRNLPALRIQYKDYAVWQEGFKTGDAYKTQEAYWLKQLEGE
                     LPVLDLPADHARPPVRSFAGDKVSFTLDPEVASGLHKX"
     CDS_motif       141..206
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0001"
                     /evalue="4.30E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg4_1"
                     /protein_end="68"
                     /protein_start="46"
                     /score="35.2"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIREFGELY"
     CDS_motif       237..266
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0002"
                     /evalue="1.20E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg4_1"
                     /protein_end="88"
                     /protein_start="78"
                     /score="17.8"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
     CDS             562..4278
                     /NRPS_PKS="Domain: AMP-binding (177-571). E-value:
                     1.7e-112. Score: 367.9. Matches aSDomain:
                     nrpspksdomains_ctg4_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (678-745). E-value: 1.7e-27. Score:
                     87.3. Matches aSDomain: nrpspksdomains_ctg4_2_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (755-1063). E-value:
                     9.1e-155. Score: 508.3. Matches aSDomain:
                     nrpspksdomains_ctg4_2_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1075-1231). E-value: 3.4e-45.
                     Score: 145.5. Matches aSDomain:
                     nrpspksdomains_ctg4_2_TIGR01720.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     369.2; E-value: 4.6e-112)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-122, bitscore:
                     403.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.4e-16, bitscore:
                     53.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.1e-70, bitscore:
                     232.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELVD
                     KLELTRDMSRNPVFDAMLVVQNNDYEPLHLHDLQMKPAQVSHLVSKFDLTLQASEGDGN
                     IHFLFEYSTALFEKTTIERWASHLTNVLSIIGKNPEVTLNHIEILTQEERHQLLNEFNT
                     GQANQYGVQTISQLFEQQAARTPKASALVSGDKTLTYQELDEWSNGIARALRSRGVKPD
                     TPVGIMMNRSFSMIASILGVWKAGGCYVPIDPEYPTERKRYILSDSGTKLLMTINEADR
                     GVLADFEGEILTIENVEADDKSPLPQMSSAHHLAYIIYTSGTTGRPKGVMVEHKGIANT
                     LQWRRNAYAFNETDTILQLFSFSFDGFLTSMFTPLLSGAKAVLLHEEEAKDILAIKHQL
                     SRQRITHMIIVPVLYRALLDIVQPEDVKTLRVVTLAGEAADRELIDRSLAICPHTELAN
                     EYGPTENSVATTVMRHMEKQAYVSIGQPIDGTQVLILNSNHQLQPIGVAGELCIAGTGL
                     ARGYVNLPELTERAFTQNPFKPETRMYRTGDAARWMADGTLEYLGRIDDQVKIRGYRVE
                     TKEIESVIRCINGVKDAAVVAHVTASGQTELSAYVVTKPELSTNAVRSELQNKLPVFMH
                     PAFIEKLDSLPLSPNGKLDRGALPKPVYNHEGERPFLPPASKMEQILADIWKEVLGAEK
                     IGTADSFFELGGDSIKALQVSARLHRIGKQMAVKDLFSHPTIQELAAYIRDSDTSSSQA
                     AVEGDVQWSPVQKWFLSQDIKEKHHFNQSVMLHRSTSVQEDALRKTLKAITCHHDALRM
                     VFTQNEQGKWDQYNRPLSHSDDALYGLQMIDLCPDGNRPYEPLIKRHVLDIQQKMDLKN
                     GPLLQAGLFHTIDGDFLFLSAHHLVVDGISWRVLLEDLALGYRQAAGGEDIKLPPKTSS
                     FKAYTKKLSDYAESQQLMKQLKYWREAEEYQTEALPFDHIDGTRAHDGQRSTISFTLNE
                     KETAALLKDANSAYNTDTQDMLLASVILALRHWTNQSAFKLSLEGHGREDVLEGIDVSR
                     TVGWFTAIYPLLVKLNADLPDSEEYMVHVLKTTKDTLRRVPDKGFGYGVIKYLTPPGKK
                     DIDFTGAPEISFNYLGQFESGSTAEVPKEDAFSFSPLGAGGDISTTWNREQSLDISAIA
                     AEGKMTVNMTYDTTRFQHKTIEQLSETCSQFLLQLIEHCQNKSETEKTISDYDDQELTE
                     DALQEIADMLSFH"
     CDS_motif       637..753
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0001"
                     /evalue="3.60E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg4_2"
                     /protein_end="64"
                     /protein_start="25"
                     /score="64.4"
                     /tool="antismash"
                     /translation="RETALEAFEHQDYPFEELVDKLELTRDMSRNPVFDAMLV"
     aSDomain        1093..2274
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_AMP-binding.1"
                     /evalue="1.70E-112"
                     /label="ctg4_2_AMP-binding.1"
                     /locus_tag="ctg4_2"
                     /protein_end="571"
                     /protein_start="177"
                     /score="367.9"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEQQAARTPKASALVSGDKTLTYQELDEWSNGIARALRSRGVKPD
                     TPVGIMMNRSFSMIASILGVWKAGGCYVPIDPEYPTERKRYILSDSGTKLLMTINEADR
                     GVLADFEGEILTIENVEADDKSPLPQMSSAHHLAYIIYTSGTTGRPKGVMVEHKGIANT
                     LQWRRNAYAFNETDTILQLFSFSFDGFLTSMFTPLLSGAKAVLLHEEEAKDILAIKHQL
                     SRQRITHMIIVPVLYRALLDIVQPEDVKTLRVVTLAGEAADRELIDRSLAICPHTELAN
                     EYGPTENSVATTVMRHMEKQAYVSIGQPIDGTQVLILNSNHQLQPIGVAGELCIAGTGL
                     ARGYVNLPELTERAFTQNPFKPETRMYRTGDAARWMADGTLEYLGRIDDQVKIR"
     aSModule        1093..4254
                     /complete
                     /domains="nrpspksdomains_ctg4_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg4_2_PCP.1"
                     /domains="nrpspksdomains_ctg4_2_Epimerization.1"
                     /domains="nrpspksdomains_ctg4_2_TIGR01720.1"
                     /locus_tags="ctg4_2"
                     /monomer_pairings="Tyr -> D-Tyr"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1279..1320
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0002"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg4_2"
                     /protein_end="253"
                     /protein_start="239"
                     /score="18.5"
                     /tool="antismash"
                     /translation="LGVWKAGGCYVPID"
     CDS_motif       1504..1563
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0003"
                     /evalue="2.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_2"
                     /protein_end="334"
                     /protein_start="314"
                     /score="35.0"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGRPKGVMVEH"
     CDS_motif       2068..2157
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0004"
                     /evalue="2.70E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_2"
                     /protein_end="532"
                     /protein_start="502"
                     /score="48.4"
                     /tool="antismash"
                     /translation="PIGVAGELCIAGTGLARGYVNLPELTERAF"
     CDS_motif       2239..2304
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0005"
                     /evalue="3.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg4_2"
                     /protein_end="581"
                     /protein_start="559"
                     /score="35.1"
                     /tool="antismash"
                     /translation="YLGRIDDQVKIRGYRVETKEIE"
     aSDomain        2596..2796
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_PCP.1"
                     /evalue="1.70E-27"
                     /label="ctg4_2_PCP.1"
                     /locus_tag="ctg4_2"
                     /protein_end="745"
                     /protein_start="678"
                     /score="87.3"
                     /tool="antismash"
                     /translation="EQILADIWKEVLGAEKIGTADSFFELGGDSIKALQVSARLHRIGK
                     QMAVKDLFSHPTIQELAAYIRD"
     aSDomain        2827..3750
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_Epimerization.1"
                     /evalue="9.10E-155"
                     /label="ctg4_2_Epimerization.1"
                     /locus_tag="ctg4_2"
                     /protein_end="1063"
                     /protein_start="755"
                     /score="508.3"
                     /tool="antismash"
                     /translation="EGDVQWSPVQKWFLSQDIKEKHHFNQSVMLHRSTSVQEDALRKTL
                     KAITCHHDALRMVFTQNEQGKWDQYNRPLSHSDDALYGLQMIDLCPDGNRPYEPLIKRH
                     VLDIQQKMDLKNGPLLQAGLFHTIDGDFLFLSAHHLVVDGISWRVLLEDLALGYRQAAG
                     GEDIKLPPKTSSFKAYTKKLSDYAESQQLMKQLKYWREAEEYQTEALPFDHIDGTRAHD
                     GQRSTISFTLNEKETAALLKDANSAYNTDTQDMLLASVILALRHWTNQSAFKLSLEGHG
                     REDVLEGIDVSRTVGWFTAIYPLLVKL"
     CDS_motif       2977..3018
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0006"
                     /evalue="1.00E-03"
                     /label="Cy2"
                     /locus_tag="ctg4_2"
                     /protein_end="819"
                     /protein_start="805"
                     /score="11.7"
                     /tool="antismash"
                     /translation="HHDALRMVFTQNEQ"
     CDS_motif       3223..3288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0007"
                     /evalue="2.20E-11"
                     /label="NRPS-E2"
                     /locus_tag="ctg4_2"
                     /protein_end="909"
                     /protein_start="887"
                     /score="35.9"
                     /tool="antismash"
                     /translation="LFLSAHHLVVDGISWRVLLEDL"
     CDS_motif       3694..3741
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0008"
                     /evalue="1.60E-08"
                     /label="NRPS-E5"
                     /locus_tag="ctg4_2"
                     /protein_end="1060"
                     /protein_start="1044"
                     /score="26.6"
                     /tool="antismash"
                     /translation="DVSRTVGWFTAIYPLL"
     aSDomain        3787..4254
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_TIGR01720.1"
                     /evalue="3.40E-45"
                     /label="ctg4_2_TIGR01720.1"
                     /locus_tag="ctg4_2"
                     /protein_end="1231"
                     /protein_start="1075"
                     /score="145.5"
                     /tool="antismash"
                     /translation="HVLKTTKDTLRRVPDKGFGYGVIKYLTPPGKKDIDFTGAPEISFN
                     YLGQFESGSTAEVPKEDAFSFSPLGAGGDISTTWNREQSLDISAIAAEGKMTVNMTYDT
                     TRFQHKTIEQLSETCSQFLLQLIEHCQNKSETEKTISDYDDQELTEDALQEI"
     CDS_motif       3802..3864
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0009"
                     /evalue="9.80E-10"
                     /label="NRPS-E6"
                     /locus_tag="ctg4_2"
                     /protein_end="1101"
                     /protein_start="1080"
                     /score="30.6"
                     /tool="antismash"
                     /translation="TKDTLRRVPDKGFGYGVIKYL"
     CDS_motif       3904..3933
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0010"
                     /evalue="4.00E-03"
                     /label="NRPS-E7"
                     /locus_tag="ctg4_2"
                     /protein_end="1124"
                     /protein_start="1114"
                     /score="9.8"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     aSDomain        4307..4393
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_3_NRPS-COM_Nterm.1"
                     /evalue="1.40E-15"
                     /label="ctg4_3_NRPS-COM_Nterm.1"
                     /locus_tag="ctg4_3"
                     /protein_end="29"
                     /protein_start="0"
                     /score="48.1"
                     /tool="antismash"
                     /translation="MDNIKKIKNIYPLSHMQEGMLFHSFLRKE"
     CDS             4307..8125
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-29). E-value: 1.4e-15.
                     Score: 48.1. Matches aSDomain:
                     nrpspksdomains_ctg4_3_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (8-309). E-value:
                     1.2e-116. Score: 380.8. Matches aSDomain:
                     nrpspksdomains_ctg4_3_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-867). E-value:
                     2.9e-110. Score: 360.5. Matches aSDomain:
                     nrpspksdomains_ctg4_3_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (973-1040). E-value: 3.3e-23. Score:
                     73.6. Matches aSDomain: nrpspksdomains_ctg4_3_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1060-1263). E-value:
                     1.7e-41. Score: 135.0. Matches aSDomain:
                     nrpspksdomains_ctg4_3_Thioesterase.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 342;
                     E-value: 7.9e-104)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="Condensation (E-value: 5.5e-87, bitscore:
                     286.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-114, bitscore:
                     376.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.3e-16, bitscore:
                     54.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNIKKIKNIYPLSHMQEGMLFHSFLRKEEGAYVEQSLFTIKGSL
                     SYDWFQHSIQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLYSEDISHLPTNDQN
                     EYIERFKEKDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLGIVMQEFM
                     QIYQSIHAGKPLLLDPVRPYSTYISWLTNRDKEKAAAHWDTYLKNYSTPSPLPRVSDKE
                     TKEGYHREDFIFSLNKPLTDKLIETAKQHGVTLATLIQAVWGVMLQQYNRTDDVVFGAV
                     VSGRPSEIPGVEQMIGLFINTIPIRIKTHQDETFQELLIRCQKEMLEAEPFTCQPLFDI
                     QANTALKQELIDHIIVFENYPLQQKIADSADQTDSPLQISQVQVSEQSGYNFNLVVAPG
                     EELIIKFSYNAFIYDAAWISCIKRQFTQALSTAAQHPHTPIADFSFLDATEKEQIVTQF
                     NNTKTEYPKNHTIIDLFREQAEKTPDHTALVYGNMSISYEELDKRSNALARELIQKGFR
                     KNETAGILAAHSPEFMISVLAVLKAGGAYLPLDAELPPERVSFMLEETQAKMLIVQKGL
                     EQNATFSGTCIISVAQGLMEENDIPINISSSPDDLAYIMYTSGSTGRPKGVMITNRNVV
                     SLVRNSNYTSASGDDRFIMTGSISFDAVTFEMFGALLHGASLHIIDKSTMLTPDRFGAY
                     LLENDITVLFLTTALFNQLAQVRADMFRGLHTLYVGGEALSPALMNAVRHACPDLALHN
                     IYGPTENTTFSTFFEIKRDYAGPIPIGKPISNSTAYILDTKGRLLPIGVPGELCVGGDG
                     VAKGYLNKDDLTNAVFSPHPFLPEERIYRTGDLARWLPDGNLEYISRIDRQMKIRGKRI
                     EPAEIEARLLEMEGVQEAAVTLREKDGEAQLYTHYVGDHKKTDTDFRADLARVLPDYMI
                     PQHWVRVERMPLTGNGKIDRSALPIPENKPAKRQNIILPRNLVEEELANIWKQVLGVNT
                     ISIDDDFFAIGGHSLKALQVIHTLKHQQNIDIPIDFLFEHPTIAQLAEKLYSKQLTAAD
                     EQHVIKLNQYGAQNLFCFPPISGFGIYFKDLALLLNEKAAVYGFHFIEQDTRIEQYVNC
                     MRDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLPIDTGNDE
                     SAAYLPEAVREKVMKKKRNYQAYWAQLLNEGHIKASIHFIEAGIHPETSENTGLTKWEG
                     ACGNYSEYSGFGAHKDMLEGTYAEKNADIILDILEKITSNKAIPHKQ"
     aSDomain        4331..5233
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_3_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.20E-116"
                     /label="ctg4_3_Condensation_DCL.1"
                     /locus_tag="ctg4_3"
                     /protein_end="309"
                     /protein_start="8"
                     /score="380.8"
                     /tool="antismash"
                     /translation="NIYPLSHMQEGMLFHSFLRKEEGAYVEQSLFTIKGSLSYDWFQHS
                     IQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLYSEDISHLPTNDQNEYIERFKE
                     KDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLGIVMQEFMQIYQSIHA
                     GKPLLLDPVRPYSTYISWLTNRDKEKAAAHWDTYLKNYSTPSPLPRVSDKETKEGYHRE
                     DFIFSLNKPLTDKLIETAKQHGVTLATLIQAVWGVMLQQYNRTDDVVFGAVVSGRPSEI
                     PGVEQMIGLFINTIPIRIKT"
     aSModule        4331..8095
                     /complete
                     /domains="nrpspksdomains_ctg4_3_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg4_3_AMP-binding.1"
                     /domains="nrpspksdomains_ctg4_3_PCP.1"
                     /domains="nrpspksdomains_ctg4_3_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg4_3"
                     /monomer_pairings="Ile -> Ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4337..4378
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_3_0001"
                     /evalue="3.90E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="ctg4_3"
                     /protein_end="24"
                     /protein_start="10"
                     /score="15.5"
                     /tool="antismash"
                     /translation="YPLSHMQEGMLFHS"
     CDS_motif       4397..4513
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_3_0002"
                     /evalue="1.30E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg4_3"
                     /protein_end="69"
                     /protein_start="30"
                     /score="46.4"
                     /tool="antismash"
                     /translation="GAYVEQSLFTIKGSLSYDWFQHSIQAIIDRHDIFRTVFL"
     CDS_motif       4739..4804
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_3_0003"
                     /evalue="1.00E-12"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg4_3"
                     /protein_end="166"
                     /protein_start="144"
                     /score="40.4"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVMQEFMQIY"
     CDS_motif       5129..5224
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_3_0004"
                     /evalue="1.30E-21"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg4_3"
                     /protein_end="306"
                     /protein_start="274"
                     /score="69.0"
                     /tool="antismash"
                     /translation="DVVFGAVVSGRPSEIPGVEQMIGLFINTIPIR"
     CDS_motif       5273..5389
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_3_0005"
                     /evalue="1.40E-16"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg4_3"
                     /protein_end="361"
                     /protein_start="322"
                     /score="52.9"
                     /tool="antismash"
                     /translation="QKEMLEAEPFTCQPLFDIQANTALKQELIDHIIVFENYP"
     aSDomain        5729..6907
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_3_AMP-binding.1"
                     /evalue="2.90E-110"
                     /label="ctg4_3_AMP-binding.1"
                     /locus_tag="ctg4_3"
                     /protein_end="867"
                     /protein_start="474"
                     /score="360.5"
                     /specificity="substrate consensus: Ile"
                     /tool="antismash"
                     /translation="FREQAEKTPDHTALVYGNMSISYEELDKRSNALARELIQKGFRKN
                     ETAGILAAHSPEFMISVLAVLKAGGAYLPLDAELPPERVSFMLEETQAKMLIVQKGLEQ
                     NATFSGTCIISVAQGLMEENDIPINISSSPDDLAYIMYTSGSTGRPKGVMITNRNVVSL
                     VRNSNYTSASGDDRFIMTGSISFDAVTFEMFGALLHGASLHIIDKSTMLTPDRFGAYLL
                     ENDITVLFLTTALFNQLAQVRADMFRGLHTLYVGGEALSPALMNAVRHACPDLALHNIY
                     GPTENTTFSTFFEIKRDYAGPIPIGKPISNSTAYILDTKGRLLPIGVPGELCVGGDGVA
                     KGYLNKDDLTNAVFSPHPFLPEERIYRTGDLARWLPDGNLEYISRIDRQMKIR"
     CDS_motif       5915..5956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_3_0006"
                     /evalue="8.20E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg4_3"
                     /protein_end="550"
                     /protein_start="536"
                     /score="18.9"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       6140..6196
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_3_0007"
                     /evalue="4.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_3"
                     /protein_end="630"
                     /protein_start="611"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYIMYTSGSTGRPKGVMIT"
     CDS_motif       6701..6790
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_3_0008"
                     /evalue="8.80E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_3"
                     /protein_end="828"
                     /protein_start="798"
                     /score="46.8"
                     /tool="antismash"
                     /translation="PIGVPGELCVGGDGVAKGYLNKDDLTNAVF"
     CDS_motif       6872..6937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_3_0009"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg4_3"
                     /protein_end="877"
                     /protein_start="855"
                     /score="30.2"
                     /tool="antismash"
                     /translation="YISRIDRQMKIRGKRIEPAEIE"
     aSDomain        7226..7426
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_3_PCP.1"
                     /evalue="3.30E-23"
                     /label="ctg4_3_PCP.1"
                     /locus_tag="ctg4_3"
                     /protein_end="1040"
                     /protein_start="973"
                     /score="73.6"
                     /tool="antismash"
                     /translation="EEELANIWKQVLGVNTISIDDDFFAIGGHSLKALQVIHTLKHQQN
                     IDIPIDFLFEHPTIAQLAEKLY"
     aSDomain        7487..8095
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_3_Thioesterase.1"
                     /evalue="1.70E-41"
                     /label="ctg4_3_Thioesterase.1"
                     /locus_tag="ctg4_3"
                     /protein_end="1263"
                     /protein_start="1060"
                     /score="135.0"
                     /tool="antismash"
                     /translation="QNLFCFPPISGFGIYFKDLALLLNEKAAVYGFHFIEQDTRIEQYV
                     NCMRDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLPIDTGN
                     DESAAYLPEAVREKVMKKKRNYQAYWAQLLNEGHIKASIHFIEAGIHPETSENTGLTKW
                     EGACGNYSEYSGFGAHKDMLEGTYAEKNADIILDILEKIT"
     CDS_motif       7640..7711
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_3_0010"
                     /evalue="3.10E-13"
                     /label="NRPS-te1"
                     /locus_tag="ctg4_3"
                     /protein_end="1135"
                     /protein_start="1111"
                     /score="42.0"
                     /tool="antismash"
                     /translation="QPEGPYVLLGYSAGGNLAFEVAQA"
     CDS             8233..8625
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MDHLSFLTFIMLILASYRLTHLIVFDKITEFIRKPFMKKKRIVDQ
                     NGHVDEKSVPASNFGYMLNCYWCAGVWCAILIGLGYLFLPRIAIPLIFILAIAGAQAIL
                     ETAVGVGVKLIDVLKSLQTMINDKKS"
     CDS             8761..10293
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MKVCQKSIVRFLVSLIIGTFVISVPFMANAQSDRELRAVWIASVL
                     NIDWPSKKGLSVKEQKQEYIKLLDDVQKMGMNAVIVQIKPTADAFYPSAYGPWSEYLTG
                     VQGKDPGYDPLAFMIEETHKRNLEFHAWFNPYRITMNHTDLNKLSESHPARKHPDWVAA
                     YGNQLYYHPGIPEARDFIVKGIEEVVKHYDIDAVHMDDYFYPYKIAGQEFPDQAQYEQY
                     GKGAFSYIDDWRRDNVNQLVKQINQTIKAAKPYVKFGISPFGVWRNAADDPTGSNTKAG
                     VRNYDDLYADTRHWIQEGDIDYIAPQIYWSIGFNAAAYDVLADWWSNEVKNRPVHLYIG
                     QAAYKINNNFDPLWSDPEEYVRQITLNRQLELVKGSMHFSLKDLNKNPLGIKDRLSTDL
                     YSKPALVPQMPWLDNTAPKKPKLTKVTEDKNGNLLQIKDHPSNQKTKETAYYAIYRAEG
                     KKQRTLLATQRKTHEQQTFLDNTADPNKKYTYYVTSADRLHNESKASKRTTK"
     CDS             10811..11953
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 458.4; E-value:
                     3.1e-139)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_6"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.9e-39, bitscore:
                     129.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.5e-28, bitscore:
                     91.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.8e-55, bitscore:
                     182.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTKEQQMVREMVKDFAKKEIAPHAEHVDQTGEFPMQTFKKM
                     GELGLMGIPFPEEYGGSGGDTISYALAVEEVGKACGSTGLSYAAAVSLGASPLYYFGTE
                     EQKQTHLTPLASGTALGSFGLTEPNAGSDAGGTQTKAISNGDEYVINGEKCWITNASYA
                     RTVIVTAVTGKNKDGKNIISALIVPTDTPGLTITSPYDKMGVRGSNTAEILLEDVRVPA
                     ANLLGDPTKGFKQFLYTLDGGRISIAALAVGIAQAALDASLAYAKERKQFGQPISSFQA
                     IQFKLADMAMEIDLARQMVLKAAWLKDHNHPFTKEAAYAKLFASEMATRACNQAIQIHG
                     GSGYMKEYGVERMLRDAKLMEIGEGTSEIQRLVIARQLLK"
     CDS             11997..13646
                     /NRPS_PKS="Domain: AMP-binding (13-445). E-value: 2.2e-105.
                     Score: 344.4. Matches aSDomain:
                     nrpspksdomains_ctg4_7_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     458.3; E-value: 4.3e-139)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_7"
                     /sec_met_domain="AMP-binding (E-value: 1e-114, bitscore:
                     378.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELIHSTIGRLLEQTADAYPDRDAVVYPDRNIRYTYAQFDSLCR
                     QTAKGLMRMGIGKGDHVAIWASNIPEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQ
                     SDAAALIIMDSYRGTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLPGMY
                     HWDDTTILAKTVTDAELEERMNSLDKDDVINMQYTSGTTGFPKGVMLTHFNVINNAANI
                     AECMVLTSQDRMCIPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCT
                     ALHGVPTMFIAELHHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQ
                     TEASPVITQTRANDSFIRRVETTGRALPHTEVKIVEPGTCQEIQRGMQGELCTRGYHVM
                     KGYYKDKEATRKAINHDGWLFTGDLAVMDEDGYCRITGRLKDMLIRGGENIYPREIEEF
                     LYRHPAVLDVQVVGVPDAKFGEEAAAWIKLKDGKSVSPDELKAYCKGKIARHKIPRYVI
                     FTDDYPMTASGKIQKYKLREKTIEMFNLSSSQ"
     aSDomain        12036..13331
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_7_AMP-binding.1"
                     /evalue="2.20E-105"
                     /label="ctg4_7_AMP-binding.1"
                     /locus_tag="ctg4_7"
                     /protein_end="445"
                     /protein_start="13"
                     /score="344.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EQTADAYPDRDAVVYPDRNIRYTYAQFDSLCRQTAKGLMRMGIGK
                     GDHVAIWASNIPEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQSDAAALIIMDSYR
                     GTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLPGMYHWDDTTILAKTVT
                     DAELEERMNSLDKDDVINMQYTSGTTGFPKGVMLTHFNVINNAANIAECMVLTSQDRMC
                     IPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCTALHGVPTMFIAEL
                     HHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQTEASPVITQTRAN
                     DSFIRRVETTGRALPHTEVKIVEPGTCQEIQRGMQGELCTRGYHVMKGYYKDKEATRKA
                     INHDGWLFTGDLAVMDEDGYCRITGRLKDMLIR"
     CDS_motif       12582..12632
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_7_0001"
                     /evalue="2.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_7"
                     /protein_end="212"
                     /protein_start="195"
                     /score="23.3"
                     /tool="antismash"
                     /translation="QYTSGTTGFPKGVMLTH"
     CDS_motif       13152..13229
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_7_0002"
                     /evalue="2.50E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_7"
                     /protein_end="411"
                     /protein_start="385"
                     /score="13.5"
                     /tool="antismash"
                     /translation="GMQGELCTRGYHVMKGYYKDKEATRK"
     CDS             13656..14990
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     653.5; E-value: 6.7e-198)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_8"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 9.6e-16,
                     bitscore: 52.6, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 6.4e-09, bitscore:
                     30.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTKVLIANRGEIAMRIIRTCSRLGIKTVAVYSEADKDALHTKAA
                     TEAYLIGESRVSESYLNIERIIKTAKKANADAIHPGYGLLSENSRFAERCKQENIVFIG
                     PSPDIIAKMGSKIEARKAMEAAGVPVVPGVSESLGDIEAACRTASQIGYPVMLKASAGG
                     GGIGMQRVENEEALKKAYEGNKKRAADFFGDGSMYIEKVIEHARHIEVQLLADQHGHTV
                     HLFERDCSVQRRHQKVIEEAPSPFVDDELRMKIGQTAVKAAKAIGYTNAGTTEFIVDQK
                     QNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLRIAAGHTLTFSQKDIQRNGHAIEVRIY
                     AEDPKTFFPSPGTITAFSLPDQKGVRHECAVAKDSTVTPFYDPMIAKMIVKGQTRTEAI
                     EKLETALRDYRVEGIKTNLPLLIQAAATKAFKEGDVTTDFLKQHL"
     CDS             15005..15226
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MTVSIQMAGNLWKVHVKAGDQIEKGQEVAILESMKMEIPIVADRS
                     GIVKEVKKNEGDFVNEGDVLLELSDSTQ"
     CDS             15241..16140
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 266.1;
                     E-value: 1.1e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_10"
                     /sec_met_domain="HMGL-like (E-value: 1e-49, bitscore:
                     164.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYPKKVTIKEVGPRDGLQNEPVWIATEDKITWINQLSRTGLSYI
                     EITSFVHPKWIPALRDAIDVAKGIDRLKGVTYAALVPNQRGLENALEGGINEACVFMSA
                     SETHNRKNINKSTSESLHILKQVNNDAQKANLTTRAYLSTVFGCPYEKDVPIEQVIRLS
                     EALFEFGISELSLGDTIGAANPAQVETVLEALLARFPANQIALHFHDTRGTALANMVTA
                     LQMGITVFDGSAGGLGGCPYAPGSSGNAATEDIVYMLEQMDIKTNVKLEKLLSAAKWIE
                     EKMGKPLPSRNLQVFKSS"
     CDS             16161..16943
                     /NRPS_PKS="Domain: ECH (10-252). E-value: 1.4e-70. Score:
                     229.2. Matches aSDomain: nrpspksdomains_ctg4_11_ECH.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 267.2; E-value:
                     1.8e-81)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MGESILFTVKNEHIALITLNRPQAANALSAEMLRNLQMILQEIEF
                     NSNIRCVILTGTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAI
                     NGSALGGGLELALACDLRIATEAAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIY
                     TGRRVTAHEAKEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDL
                     ATGLAIEQKAYEQTIPTKDRREGLQAFQEKRRAVYKGI"
     aSDomain        16191..16916
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_11_ECH.1"
                     /evalue="1.40E-70"
                     /label="ctg4_11_ECH.1"
                     /locus_tag="ctg4_11"
                     /protein_end="252"
                     /protein_start="10"
                     /score="229.2"
                     /tool="antismash"
                     /translation="NEHIALITLNRPQAANALSAEMLRNLQMILQEIEFNSNIRCVILT
                     GTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAINGSALGGGLE
                     LALACDLRIATEAAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIYTGRRVTAHEA
                     KEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDLATGLAIEQKA
                     YEQTIPTKDRREGLQAFQEK"
     CDS             16960..18489
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 544.8; E-value: 3.8e-165)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_12"
                     /transl_table=11
                     /translation="MDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLFDDD
                     IELEDAFFAECMSDGLPADGVVTAIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIRIQ
                     ETAEKLNCPLIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSA
                     AGGAYIPAFCDIVVMVDGNASMYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGDIL
                     AETEEEAIQLARAYLSYFPANFQEKAPIHEKRPPKHFDTPLADVIPQNQNAPFDMHELI
                     ERVIDEDSFFEIKALFAPELLTGLARINGQPVGIVANQPKVKGGVLFHDSADKAAKFIT
                     LCDAFHIPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYGAG
                     LYAMAGPAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKIAELPEEERAAFISSKREEYK
                     EDINIYRLASEMIIDAVIPANSLRDELAKRLKAYMTKEMTFTNRKHPVYPV"
     CDS             18659..19858
                     /locus_tag="ctg4_13"
                     /transl_table=11
                     /translation="MYHLYSHNDLDGVGCGIVAKLAFGKDVEVRYNSVNGLNAQVQYFL
                     EKAKESNRQDTLFITDLAVNEENEERLNEYVHAGGKVKLIDHHKTALHLNEHEWGFVQV
                     EYDDGRLTSATSLLYGYLVENGFMKPTNALDQFTELVRQYDTWEWERYDQKQAKRLNDL
                     FFLLSIDEFEAKMIQRLSAHDEFFFDDFEEKLLDLEDEKIERYLRRKKREMVQTFVHEH
                     CVGIVHAESYHSELGNRLGKDNPHLDYIAILSMGSKRVSLRTIHDYIDVSEIAGRYGGG
                     GHAKASGCSITDEVYELFVAEAFRFDPVRPDAFRNIYNLKGSANGSLYENRAQMRFFLF
                     PLDNEWNIQINGETQDETFAAFEEAEWFIKRNYAASLVRDEVFVAFLAENLKLANQHRK
                     "
     CDS             complement(19907..20512)
                     /gene_functions="other (smcogs) SMCOG1188:hypothetical
                     protein (Score: 144.1; E-value: 4.8e-44)"
                     /gene_kind="other"
                     /locus_tag="ctg4_14"
                     /transl_table=11
                     /translation="MKNVGSLISEILTWLTNMGYAGIAIGLMIEIIPSEIVLAYGGYMV
                     SEGTIGFIGAIIAGVIGGTIAQIFIYWIGRYGGRPFLDKYGKYLLIKKHHIDMSENWFQ
                     KYGAGVVFSARFIPVVRHAISIPAGIARMPFLKFVVLTVLAIIPWSILFVYLGIQLGSQ
                     WDDVENIAGTYTTPIMILAVVVIALYFVIKKRTAIFKR"
     CDS             complement(20576..21469)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 230.1; E-value:
                     5.6e-70)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_15"
                     /sec_met_domain="NTP_transf_3 (E-value: 1e-10, bitscore:
                     36.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEE
                     AAESGIEDILIITGRNKRSIEDHFDRSAELEFNLREKGKTETLKEMQQIADLANIHYIR
                     QKEPLGLGHAVLCAEHFIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGVQSV
                     LPEDVSKYGIINTSGSQGHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIG
                     RGAGNEIQLTDALREVCRKEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRSEMRSQLL
                     AYLEDVIKRETKEMLR"
     CDS             22518..24059
                     /locus_tag="ctg4_16"
                     /transl_table=11
                     /translation="MRKKCSVCLWILVLLLSCLAGKSAYAATSSTIAKHVGNSNPLIDH
                     HLGADPVALTYNGRVYIYMSSDDYEYNSNGTIKDNSFANLNRVFVISSADMVNWTDHGA
                     IPVASANGANGGRGIAKWAGASWAPSIAVKKINGKDKFFLYFANSGGGIGVLTADSPIG
                     PWTDPIGKPLVTPSTPGMSGVVWLFDPAVFVDDDGTGYLYAGGGVPGGSNPTQAQWVNP
                     KTARVIKLGPDMTSVVGSASTIDAPFMFEDSGLHKYNGTYYYSYCINFGGTHPADKPPG
                     EIGYMTSSSPMGPFTYRGHFLKNPGAFFGGGGNNHHAVFNFKNEWYVVYHAQTVSSALF
                     GAGKGYRSPHINKLVHNPDGSIQEVAANYAGVTQLSNLNPYNRVEAETFAWNGRILTEK
                     STAPGGPVNNQHVTSIQNGDWIAVGNADFGAGGARTFKANVASTLGGKIEVRLDSADGK
                     LVGTLNVPSTGGAQTWREIETAVSGATGVHKVFFVFTGTGTGNLFNFDYWQFTQR"
     CDS             24189..25457
                     /locus_tag="ctg4_17"
                     /transl_table=11
                     /translation="MIPRIKKTICVLLVCFTMLSVMLGPGATEVLAASDVTVNVSAEKQ
                     VIRGFGGMNHPAWAGDLTAAQRETAFGNGQNQLGFSILRIHVDENRNNWYKEVETAKSA
                     VKHGAIVFASPWNPPSDMVETFNRNGDTSAKRLKYNKYAAYAQHLNDFVTFMKNNGVNL
                     YAISVQNEPDYAHEWTWWTPQEILRFMRENAGSINARVIAPESFQYLKNLSDPILNDPQ
                     ALANMDILGTHLYGTQVSQFPYPLFKQKGAGKDLWMTEVYYPNSDNNSADRWPEALDVS
                     QHIHNAMVEGDFQAYVWWYIRRSYGPMKEDGTISKRGYNMAHFSKFVRPGYVRIDATKN
                     PNASVYVSAYKGDNKVVIVAINKSNTGVNQNFVLQNGSASNVSRWITSSSSNLQPGTNL
                     TVSGNHFWAHLPAQSVTTFVVNR"
     CDS             complement(25717..25980)
                     /locus_tag="ctg4_18"
                     /transl_table=11
                     /translation="MDEILKQYMVMYKEMSNVINGPDYPGKEKDIQHQKDQIEVYEKQL
                     QQGFSTDYDYDVFADSVIKCAYGDMTLEDLEAVYYGLTTPFF"
     CDS             complement(26049..27548)
                     /locus_tag="ctg4_19"
                     /transl_table=11
                     /translation="MKRSISIFITCLLITLLTMSGIMASPASAAGTKTPVAKNGQLSIK
                     GTQLVNRDGKAVQLKGISSHGLQWYGEYVNKDSLKWLRDDWGITVFRAAMYTADGGYID
                     NPSVKNKVKEAVEAAKELGIYVIIDWHILNDGNPNQNKEKAKEFFKEMSSLYGNTPNVI
                     YEIANEPNGDVNWKRDIKPYAEEVISVIRKNDPDNIIIVGTGTWSQDVNDAADDQLKDA
                     NVMYALHFYAGTHGQFLRDKANYALSKGAPIFVTEWGTSDASGNGGVFLDQSREWLKYL
                     DSKTISWVNWNLSDKQESSSALKPGASKTGGWRLSDLSASGTFVRENILGTKDSTKGIP
                     ETPAKDKPTQENGISVQYRAGDGGMNSNQIRPQLQIKNNGNTTVDLKDVTARYWYNAKN
                     KGQNFDCDYAQLGCGNMTHKFVTLHKPKQGADTYLELGFKNGTLAPGASTGNIQLRLHN
                     DDWSNYAQSGDYSFFKSNTFKTTKKITLYDKGKLIWGTEPI"
ORIGIN
        1 tacagactac agttctcggc gcacgaaccg aacaggaggc cgcagctgca tttatcaaac
       61 cgtttgatct cagccaagcg ccgctgttcc gtgcccaaat cgtaaaggta tcaaatgagc
      121 ggcacctgtt gctggttgat atgcatcaca tcatttcaga cggtgtttcc gtcaacattc
      181 tgattcggga attcggcgag ctgtacaata atcggaatct tccggcactg cgcattcaat
      241 ataaagatta tgccgtatgg caagaaggat ttaaaacagg agatgcgtac aaaacgcaag
      301 aggcgtactg gctgaagcag ctcgagggcg agctgcctgt gctggatctt cctgctgatc
      361 atgcccgccc gccggtgcga agcttcgcgg gtgacaaggt ctcatttacc ctggatccag
      421 aggttgcatc aggccttcac aagnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntcgccaa ttgccggccg gccgcacaag
      541 gatcttgagc cgatactcgg catgtttgtg aacacgctgg cgcttcggac gcgcccggag
      601 ggcgggaagc cattcgtaca gtatttgcag gaagtgcgtg agacagcatt ggaagccttt
      661 gagcaccagg attacccgtt cgaagagctt gtcgataagc ttgaattgac acgggatatg
      721 agccggaatc cagtgtttga tgcgatgtta gttgttcaaa ataatgatta cgagccattg
      781 catcttcatg atttgcaaat gaagccggca caagtttctc atctcgtttc taaattcgat
      841 ttgacactac aggcatctga gggcgacgga aacattcatt tcctttttga atattcaacc
      901 gcattgttcg agaaaaccac cattgaacgc tgggcatcgc atttaacaaa tgtacttagc
      961 atcatcggta aaaacccgga ggtgacactc aaccatatcg aaatcctgac ccaagaagag
     1021 cggcaccagc tgcttaatga gtttaacacc gggcaggcga atcaatacgg agttcaaaca
     1081 atcagtcaat tgtttgagca gcaagccgca cgaacaccaa aagcttctgc acttgtcagc
     1141 ggagacaaaa cactgacgta tcaagagttg gacgagtggt ccaatggaat cgcacgtgca
     1201 ttgcgcagcc gaggtgttaa gccggacaca ccagtaggca tcatgatgaa tcgttcgttc
     1261 agtatgatag catccatact tggtgtgtgg aaagccggag gctgttacgt tcccattgat
     1321 cctgaatacc cgacagaacg gaaacgctat atcctcagcg acagcggaac gaaactgctg
     1381 atgacaataa atgaagcgga tcggggagta cttgctgact ttgaaggaga gatcttgacg
     1441 atagaaaacg tagaggcaga cgataaatcg ccgctgccgc aaatgtcgtc tgcccatcat
     1501 ttggcttata tcatctatac ctctggaacg acgggccgtc caaaaggggt aatggtcgag
     1561 cataaaggta ttgccaacac tcttcagtgg cggcgaaacg cttatgcatt caacgagaca
     1621 gataccatcc tgcagctctt ttctttctca tttgacggct ttttaactag tatgttcaca
     1681 ccgcttttgt caggtgcaaa agccgttttg cttcatgaag aggaagcgaa ggatattctg
     1741 gccattaagc atcagctgtc tcggcaacgg attacacata tgattattgt gcctgtttta
     1801 tatcgagcgc ttttggacat agtgcagccg gaagatgtaa agacacttag agtcgtcaca
     1861 ctggcgggag aagcggctga ccgcgaattg atcgaccgca gcttagctat ttgtccgcat
     1921 accgaactcg ccaacgaata tggaccgaca gaaaacagcg tggcgactac cgtcatgaga
     1981 catatggaaa agcaggcata cgtaagcatc ggccagccga ttgacgggac tcaagtgctg
     2041 attttaaata gcaatcatca gcttcagcca atcggtgttg cgggagagct ttgtatagca
     2101 ggaacagggc ttgcaagagg gtacgtcaat cttccagaac tgacagagag agcattcacg
     2161 cagaatccat ttaaacccga aacacgaatg taccgaacag gagacgccgc cagatggatg
     2221 gccgacggta cactcgaata tctcggaaga atcgatgatc aagtcaaaat cagaggatac
     2281 cgtgtagaaa cgaaagaaat tgaatcggtc atccggtgta taaatggtgt aaaagacgcc
     2341 gcagtagttg ctcatgtaac agcgtcagga caaaccgaat taagtgctta tgtggtgaca
     2401 aaaccagagt tgagcacaaa tgctgtacgc tcagaattac aaaacaagct gccggtgttt
     2461 atgcaccctg cgtttattga aaaactggac tcacttccat tgtcaccaaa cggcaagctg
     2521 gatcgcggag cacttccaaa acctgtatac aaccacgaag gtgaacgtcc attcctcccg
     2581 ccagccagca aaatggaaca aatactggca gatatttgga aagaagtact gggggcagaa
     2641 aagatcggaa cagctgattc gttctttgaa cttggcggag attcaatcaa agcgttacag
     2701 gtatctgcgc ggcttcaccg gataggcaag caaatggcag tgaaagattt gtttagccat
     2761 ccgaccattc aagaattggc agcttatatc cgtgattcag atacaagttc cagccaagct
     2821 gcggttgagg gagacgtaca atggtcgcct gttcaaaaat ggtttctttc tcaagatata
     2881 aaagaaaaac accattttaa tcagtccgta atgctgcatc gaagcacctc tgtacaagaa
     2941 gacgcactgc gaaaaacgtt aaaagcaata acgtgtcatc atgatgcgct gcgaatggtg
     3001 tttacacaga atgaacaagg aaagtgggat caatataatc ggccgctcag tcattcggac
     3061 gacgcgttgt acggccttca gatgattgat ttatgccctg atggaaatag accgtatgaa
     3121 cctcttatca agcgccatgt acttgatatt cagcagaaaa tggatttgaa gaatggtccg
     3181 ctgctgcaag ccggtctttt ccacacaatt gacggtgatt tcttattctt atctgctcat
     3241 cacctcgtcg ttgacggcat ttcatggcgg gttctgcttg aagatttggc tttagggtat
     3301 cgccaagctg caggcgggga ggatatcaaa ctgccgccta aaacaagctc atttaaagcg
     3361 tacacgaaaa agctctctga ctacgctgaa agccagcagc taatgaaaca gctcaagtat
     3421 tggcgcgaag ccgaagagta tcaaacagag gcattgcctt ttgatcacat tgatggaact
     3481 agagcacacg atggacaacg gtccacgatt tcgtttaccc tcaacgagaa agagacagca
     3541 gcactcttaa aagacgccaa cagcgcatat aacactgata cgcaggacat gctgctcgct
     3601 tctgtcattc ttgcgctgcg ccattggacc aatcaatccg ccttcaaact atcattagag
     3661 ggccacgggc gagaggatgt attagaagga atagatgtga gccggacggt tggatggttt
     3721 accgccattt atccgttatt ggttaaattg aacgcagact tgccagattc ggaagaatac
     3781 atggttcatg tgctaaaaac aacaaaagat acactgagac gtgtacctga caaaggattc
     3841 ggctacggtg tcatcaaata tttgacgccg cctggcaaaa aagacatcga tttcacaggt
     3901 gcgccagaaa tcagctttaa ttatcttggt caatttgaaa gcggcagcac agctgaagta
     3961 cctaaggagg acgccttctc attctctccg cttggtgccg ggggtgatat cagcacaaca
     4021 tggaaccgtg aacagtcgct ggatatcagt gcaatcgctg cagaagggaa aatgactgtc
     4081 aatatgactt atgacactac ccgttttcag cacaaaacca tcgaacagct tagcgaaaca
     4141 tgcagtcaat ttttattaca gctgatcgaa cactgccaga acaaaagcga aacagaaaag
     4201 acgatcagcg attatgatga tcaagaactg accgaggacg cgctgcaaga gatcgctgat
     4261 atgctcagtt ttcactaatg aatccgtgaa gaaaggtgca gacactatgg ataacattaa
     4321 aaaaatcaag aacatttatc ctctgagtca catgcaggag gggatgctgt ttcattcctt
     4381 cctccgtaaa gaggaggggg cgtatgttga gcagtcgctc ttcaccatta aaggaagcct
     4441 cagttatgac tggttccagc acagcataca agccattatc gaccgccatg atattttcag
     4501 aaccgttttt ttgccgcacg tcccgcattt gtcgggacct cggcaagtcg tgatgacaga
     4561 acgtgaattc catttgtaca gcgaagacat ttctcatctg ccaacaaacg accagaatga
     4621 gtatattgaa cgctttaagg agaaggacaa gcaaaaaggc tttgatctgc aaaaagacat
     4681 gctgatgcgg atttctctat tcaagacagc taaagatgag catgtctgta tctggagtca
     4741 ccatcatatt ttaatggacg gatggtgcct aggtattgtt atgcaggaat ttatgcaaat
     4801 ttatcaatcg attcatgcag gaaaaccgct tttattagac cctgtccgtc cgtacagcac
     4861 ctatatttct tggctgacaa accgagacaa agaaaaagca gcggcgcact gggataccta
     4921 tttaaaaaac tacagcactc catcacctct gcctcgtgtg tcagataaag aaacaaaaga
     4981 aggttatcac cgtgaagatt tcatattttc attaaataaa ccactgacag acaagctgat
     5041 agagacagcc aaacaacacg gcgtcacgct cgctacccta attcaggcgg tctggggtgt
     5101 gatgctgcag caatataacc gcacagacga cgttgtgttt ggcgcagttg tatcaggaag
     5161 accgtcagaa atcccgggcg tggagcaaat gatagggttg tttatcaata ccataccgat
     5221 tcgaattaaa acacatcaag acgaaacgtt tcaagaactg ctcatacgat gccagaaaga
     5281 aatgttggaa gctgagccgt ttacctgcca gcctttattt gatattcagg caaacaccgc
     5341 attaaaacag gaactgattg atcacattat cgtctttgaa aactatccgt tacagcagaa
     5401 aatcgccgat tccgctgatc aaaccgattc accgctgcaa atctctcaag ttcaagtatc
     5461 cgagcaatca ggatataact ttaatcttgt cgttgctccc ggcgaagaac tgatcatcaa
     5521 attcagctat aatgcgttca tttacgacgc tgcctggatc agctgtatca agaggcaatt
     5581 tacgcaagcg cttagcacag ctgcacagca ccctcatacg ccaattgctg atttttcttt
     5641 tcttgatgca acagaaaaag agcagattgt cacacagttc aacaatacaa aaacggagta
     5701 tccaaagaat catacaatta tcgatttatt tcgcgaacaa gcagaaaaga cgccagacca
     5761 taccgcactt gtgtatggca atatgtctat ttcgtatgaa gagcttgata aacgctctaa
     5821 tgcgctcgcc agagagttaa ttcaaaaggg atttcggaaa aacgagacag ccggaatatt
     5881 ggctgcacat tctcctgaat tcatgatcag tgtgcttgcc gtattaaaag cagggggagc
     5941 atacctcccg cttgatgcgg agcttccgcc tgaacgagtc agctttatgc ttgaggaaac
     6001 gcaagcaaaa atgctgattg ttcaaaaggg gctggagcaa aacgctacgt tctcaggaac
     6061 atgtatcatt tcagttgcgc agggattgat ggaagagaac gatatcccta ttaatatcag
     6121 ctccagcccg gatgatcttg cgtacatcat gtatacctca ggatcaacag gccggccgaa
     6181 aggggtcatg atcacgaatc gcaatgtcgt gtcccttgtc agaaacagca attacacgtc
     6241 tgcgtccggt gatgaccggt ttattatgac tggatctatc agctttgacg ccgtcacctt
     6301 tgaaatgttc ggggcacttt tacatggcgc aagccttcat atcattgata aatcgacaat
     6361 gctgacacct gatcggtttg gagcgtattt gcttgaaaat gacatcacag tgctattttt
     6421 aacgacagct ctttttaatc agctggcaca ggtacgagct gacatgtttc gcggactcca
     6481 tacgttatat gtcggaggag aagcactttc gcctgctctg atgaatgctg tcaggcacgc
     6541 ctgcccagat ctcgcgcttc ataatattta cgggcctacg gaaaacacga ctttttcaac
     6601 cttttttgaa ataaagagag actatgcagg gccgattccg attggaaaac caatcagcaa
     6661 tagcaccgct tacatcttag atacaaaagg acgtcttttg ccaataggcg ttcccggcga
     6721 gctttgtgtt ggcggtgatg gggtcgctaa aggctatttg aacaaagatg acctgacaaa
     6781 tgctgttttt tctcctcatc ctttcttgcc tgaagaaaga atataccgta ccggtgattt
     6841 ggcgcgctgg ctgcctgatg gaaacttaga atacatcagc agaattgaca ggcaaatgaa
     6901 aatccgcgga aaacgaattg agcctgcaga aatagaagcg cgtctgttag aaatggaagg
     6961 cgttcaagaa gcagcagtga cattgagaga aaaagatgga gaggcgcagc tgtacactca
     7021 ttacgtcggt gatcacaaaa aaacagatac ggattttcgc gccgatttgg cgcgtgtgct
     7081 tccagactat atgatcccgc agcactgggt gcgtgtggag cggatgccgc ttaccggaaa
     7141 cggaaaaata gaccgcagcg cgctgcctat tccagaaaat aagcctgcca aacgacagaa
     7201 catcatattg ccaagaaact tggttgaaga agaattagcg aacatttgga agcaagtcct
     7261 cggtgttaac acaatcagta ttgatgatga cttctttgct attggcggac attcactaaa
     7321 agcactgcaa gtcatacata cactaaaaca tcagcagaac attgacatac cgattgattt
     7381 cttgttcgaa catccgacaa ttgctcagct tgccgaaaaa ctttattcta aacagctgac
     7441 agcggcagat gaacagcatg tgatcaaact gaaccagtac ggcgcgcaaa atcttttctg
     7501 cttcccgccg atatcaggat ttggcattta ttttaaagac cttgctttat tactgaatga
     7561 gaaggcagcc gtatacggat ttcactttat tgaacaagac acccgcattg aacaatatgt
     7621 taattgcatg agggacatac agcctgaggg cccatacgtt ttattaggct actctgcagg
     7681 cggaaacctg gcttttgaag tggcacaggc tatggagcgc aaaggattag aagtcagcga
     7741 cttcattatc gtggacgctt atctaaaaga acagcctttg cctatcgata ccgggaatga
     7801 cgaatctgca gcatatctgc ctgaagcagt cagagaaaag gtgatgaaga agaaaagaaa
     7861 ctatcaggca tattgggcac aattgctgaa tgaagggcac atcaaagcaa gcatccattt
     7921 catcgaagct ggaatccacc ccgaaaccag cgagaataca ggcttaacga aatgggaagg
     7981 cgcctgtgga aactatagtg agtactcggg ttttggcgct cataaagaca tgctggaagg
     8041 aacatatgct gaaaagaatg ctgacatcat ccttgacatt ttagaaaaga tcacttcaaa
     8101 taaagcaatc ccgcacaaac aatagagcgg attcgcggac agaggcattc tctgtccgct
     8161 tctttttgta tcaaagaatg gatcgatgac actagggaat gataacatca tcctttttct
     8221 tggaggcttg tcatggatca tttatctttt cttacgttta tcatgctgat tctagccagt
     8281 tacaggctga cacatttgat tgtattcgac aaaatcacag aatttatccg aaaacctttt
     8341 atgaaaaaga aaaggattgt tgatcaaaac gggcatgtag atgaaaaaag cgtgccggct
     8401 tctaactttg gatacatgct caattgctac tggtgtgccg gtgtttggtg tgccatcttg
     8461 attggacttg gctatctttt tttgcctcgt attgcaatac cgctgatctt tattttagcc
     8521 attgccggag cacaagcgat ccttgaaacg gctgtcggtg tcggcgtaaa acttattgac
     8581 gtgttaaaaa gtctgcaaac catgattaat gataaaaagt cctaaaagcg gttcacaaca
     8641 tgctttagga cttttttcgt ttatttagtg agatagacat tctgttaatc acccttttat
     8701 agcccgggaa taccgtaata gcgaatagtg aaagtgatgt aatgggggag aagaaacaga
     8761 atgaaggttt gccaaaagtc gattgtccgt ttccttgtca gcttgatcat cggaacgttt
     8821 gtcatttccg ttccgtttat ggccaatgcg cagtctgaca gggagctgag agccgtatgg
     8881 attgcttccg tattaaatat tgattggccg tccaaaaaag ggttatctgt gaaagagcaa
     8941 aaacaggagt atatcaaact gctggacgat gtgcagaaaa tgggaatgaa tgccgttatt
     9001 gttcagatta aaccgacggc tgatgccttt tatccgtcag cttacgggcc ttggtcggaa
     9061 tacttaaccg gtgtccaagg gaaggacccg ggctatgatc ctcttgcatt tatgattgaa
     9121 gaaacccata aacgaaattt ggaatttcac gcgtggttta acccttaccg tattacaatg
     9181 aatcatacag atcttaataa attgtctgag agtcacccgg caagaaaaca tccagattgg
     9241 gttgccgcct acggaaacca gctgtattat catccaggca ttccagaagc gagagatttt
     9301 atcgtcaaag gcattgaaga agtcgtaaaa cattatgata tcgatgctgt tcatatggat
     9361 gattattttt acccttataa aatagcagga caggaatttc ctgatcaagc acagtatgaa
     9421 caatacggaa aaggcgcttt ttcttatatc gatgactggc ggcgggacaa tgtgaaccag
     9481 cttgtcaaac aaatcaacca aacaattaaa gctgcaaaac cgtatgtcaa attcggcatc
     9541 agtccctttg gagtatggag aaacgccgca gatgacccga ccggatcgaa tacaaaagca
     9601 ggcgtcagaa attatgacga tctatatgca gacacaagac attggatcca agaaggcgac
     9661 atcgattata ttgctccgca aatttattgg agtatcggct ttaacgcagc ggcttacgac
     9721 gtgctggctg attggtggag caatgaagtc aaaaataggc ctgttcactt atatattggc
     9781 caggcagcat ataaaatcaa taacaatttt gatccgcttt ggtccgatcc tgaggaatat
     9841 gtgcggcaaa tcactttgaa ccgccagctt gaactggtga aaggaagcat gcatttcagc
     9901 ctcaaggacc tcaacaaaaa tccgcttggc atcaaagaca ggctcagcac cgatctttac
     9961 agcaagccgg cactggttcc gcaaatgcct tggcttgaca ataccgcccc aaaaaaaccg
    10021 aagcttacga aagtcaccga agacaaaaac ggcaatcttc tgcagattaa agatcaccca
    10081 tcaaatcaaa aaacgaaaga aacagcctat tatgcgatat acagagccga agggaaaaag
    10141 cagagaacat tgctggcaac gcaaagaaaa acacatgagc agcaaacctt cttagataac
    10201 acggcagatc ctaacaagaa atatacgtat tatgtcactt cagcagaccg gcttcataac
    10261 gaaagcaagg cttccaaacg aacaacaaaa taagaaatga gaaggacggc tttctaagtc
    10321 gtcttttttt aaaagtgatt ttggagacag gaaacgatgg taaaccgctg taggcggtgt
    10381 ttggacattt tccattattg gaatctgaga aactagtact aaataaaatc gaagagaaac
    10441 acgtacagga cgtgttttac gttttcattt ctagtctggt taggtgccac attatttttt
    10501 gtgctgtccg gagatgctgt gttgactgat ccggctgaag aagccttttt gacgaacttt
    10561 cttctcttgg aagcgggcac cgctcttgtt ttatgccttg tgttctttct ctatcatctt
    10621 cccggcttta tcaaagggcc aagttattgc gtttgagata tggatggtat gcgcctactg
    10681 catgtatttg ctcattccgc tgaaattatc aaaaaaatga ttcagtttta attttcagac
    10741 ttttcttgtc agggaatgat tatagaactc gcctaatagg atgttacaaa gatgtgaagg
    10801 aggaaacgat gtgaattttg agctgacaaa agaacaacaa atggtgcgtg aaatggtaaa
    10861 agattttgcg aaaaaagaaa ttgctcctca cgctgaacat gtagatcaaa caggcgagtt
    10921 cccgatgcaa acatttaaaa aaatgggtga actcggtctg atgggtattc catttccaga
    10981 agaatacggc ggatctggcg gtgatacgat ttcatatgcc ttagcggttg aagaagtcgg
    11041 caaagcctgc ggcagtactg gattaagcta tgctgcagcg gtctcgctag gcgcaagccc
    11101 tctttactac ttcggaacag aagagcaaaa acagacgcat ttgacgccgc tggcttcagg
    11161 cacagcactc ggatcattcg gcctgacgga gccaaatgcc ggctcagatg caggaggcac
    11221 tcaaacaaaa gcgatttcaa atggtgacga gtatgtaatc aacggcgaaa agtgctggat
    11281 cactaatgca agctacgcac gcacagttat tgtaaccgcc gtaacaggca aaaacaaaga
    11341 cggaaaaaac atcatctccg cattaatcgt gccaactgac acaccaggac ttacgattac
    11401 gagcccgtac gataaaatgg gcgtccgcgg ttcgaataca gcggaaattt tgcttgagga
    11461 tgtaagagtg cctgcggcca acttacttgg cgatccaaca aaagggttta aacagtttct
    11521 atatacgctg gacggagggc gaatctccat cgctgctctt gcagtcggca ttgcccaagc
    11581 ggcccttgac gcatcattgg catatgcgaa agaacgaaag cagtttggac agccgatttc
    11641 ttcctttcaa gcgattcaat ttaagcttgc tgacatggcg atggaaattg atctggcacg
    11701 gcaaatggtg ttaaaagccg cctggctgaa agaccataac cacccgttca ccaaagaagc
    11761 ggcgtacgcc aagctattcg catctgaaat ggcgacaaga gcttgcaatc aagccattca
    11821 aatccatgga ggttcaggct atatgaaaga gtatggggtg gaacggatgc tgcgggacgc
    11881 aaaattaatg gaaatcggtg aaggcacatc tgaaattcag cgtctcgtga tcgccagaca
    11941 gcttttaaaa taaaaatgta aacgctttcc tatcattaag aaaggaggaa caatgaatgg
    12001 ctgaactcat ccattccaca atcggcaggc tgctggaaca aacagctgat gcgtatcctg
    12061 atcgagacgc tgttgtgtat ccagaccgaa atatccgcta tacgtatgct caatttgaca
    12121 gtctgtgccg tcaaaccgct aaaggtctta tgcggatggg gattggaaaa ggagaccacg
    12181 tcgccatatg ggcttctaat atccctgaat ggcttgccgt ccagttcgca actgcgaaga
    12241 tcggagccgt gctcgtaacc gtcaatacca attatcaagc acacgaactg gactacttgt
    12301 taaagcaatc ggatgccgcc gcgcttatta tcatggattc atacaggggc acttcttatc
    12361 cagacatcgt gaacagttta attccagaac tgcaagaagc aaagcccggc caactgaaat
    12421 ctgaacgtta tcccttttta aaaacgctga tctatattgg caataaacgg ttgcctggca
    12481 tgtatcattg ggacgataca acgatattgg cgaaaacagt gacagatgct gagctggaag
    12541 aaagaatgaa cagcctggat aaagacgatg tgattaatat gcaatacaca tcaggaacga
    12601 cagggtttcc gaaaggcgtg atgctgaccc attttaatgt catcaataac gctgccaata
    12661 tcgctgaatg tatggtttta acctctcaag accgcatgtg catcccggtt ccgttttttc
    12721 actgctttgg atgcgtgctt ggggttttgg catgtgtatc cgtcggggca gccatgatac
    12781 ccgtgcaaga atttgatccc gttaccgtcc ttaaaacggt agaaaaagag aaatgcacag
    12841 cgctccatgg tgtgcctacc atgtttatcg ccgagctgca tcatccggat tttgatgcat
    12901 atgatctatc gacgctccga acaggaatca tggccggctc tccctgccca agtgaagtga
    12961 tgaaagctgt gattgaaagg atgggcatga aagacattac gatcgcctat ggacaaaccg
    13021 aagcctcgcc agtcattacg caaacgagag caaatgattc cttcataaga agagtcgaaa
    13081 caaccggccg tgccctgcca catactgaag tgaaaattgt agaacccggg acatgtcaag
    13141 aaattcaaag aggcatgcag ggagagctgt gcacccgtgg ctatcacgtc atgaaaggct
    13201 attataaaga caaagaagcg accagaaaag caatcaatca tgacggatgg ctgtttaccg
    13261 gagatcttgc tgtcatggat gaagacgggt actgccgcat caccggaaga ttaaaagata
    13321 tgctcatcag aggcggcgag aacatttatc cgcgggaaat tgaagaattt ttataccggc
    13381 atcccgctgt tttagatgta caggtcgttg gtgtgcctga cgccaaattc ggggaggaag
    13441 ctgcagcctg gattaaactg aaagacggta aaagcgtttc acctgatgag cttaaagcct
    13501 attgcaaagg gaaaatcgcc cgccataaaa ttccgcgtta tgttattttt acggatgact
    13561 atccgatgac ggcctcaggc aaaattcaaa aatataaact gcgagaaaaa acgattgaaa
    13621 tgttcaacct atcatcaagt caatgaggtg aaatcatgtt tacaaaagta ctgatcgcca
    13681 accgcggaga aattgcaatg agaattatcc gaacatgcag ccgtctcggc ataaaaacgg
    13741 tcgctgttta ttcagaagca gacaaggacg cgctccatac aaaagccgct acagaggctt
    13801 atttgatcgg ggaatcgaga gtcagtgaaa gttatttaaa tatagagaga atcataaaga
    13861 cggcgaaaaa agcaaatgcc gacgcgatcc accctggata tggattgtta tcagaaaaca
    13921 gccgattcgc tgaacgctgc aagcaagaaa acatcgtgtt tatcggacct tcccctgata
    13981 tcatcgcaaa gatgggcagc aaaattgaag cgcgaaaagc aatggaggct gcaggtgtcc
    14041 ctgtggtgcc gggcgtttct gaatccctcg gagatataga ggcagcctgc cgcaccgcaa
    14101 gtcaaatcgg ctatcctgtc atgctgaaag cttcagcggg cggagggggc atcggaatgc
    14161 agcgtgttga aaatgaagaa gcattaaaaa aagcgtacga gggaaacaaa aagcgcgcag
    14221 cagatttttt cggtgacggg tcgatgtata tagaaaaagt tattgaacat gcgcgtcaca
    14281 tcgaggttca gcttttggcc gatcaacacg gccatacagt acatctgttt gaacgtgatt
    14341 gctctgttca gaggcgccac caaaaagtca ttgaagaagc accgtctcca tttgtagacg
    14401 atgaactaag aatgaagatc gggcaaacag cggtaaaagc agcgaaggca atcggctata
    14461 cgaacgcagg caccaccgaa tttatagttg accagaagca aaatttttat ttcctcgaaa
    14521 tgaatacgag actgcaagtt gaacaccccg tgactgaaga aataacaggc ctggacttag
    14581 ttgagcagca gctgcggatt gctgcgggcc atacactcac attctcccaa aaagacatcc
    14641 aacggaacgg gcatgcgata gaggttcgaa tatacgcgga agatcccaag accttcttcc
    14701 cgtcaccggg tacgatcact gcgttttcac ttcctgacca aaaaggagtc agacacgaat
    14761 gtgcggtagc aaaagacagc accgttaccc ctttttatga cccgatgatc gctaagatga
    14821 ttgtcaaagg ccaaaccaga acagaagcaa ttgaaaaact ggagacagcg ctccgcgact
    14881 atcgtgtaga gggaatcaaa acaaatcttc cgcttctcat acaggctgcg gcaacaaagg
    14941 catttaaaga aggggatgtc acgactgact ttttgaaaca acacctataa aggaggcagt
    15001 tgtcatgacg gttagcatac aaatggcagg aaacctgtgg aaagtccacg tcaaagccgg
    15061 cgaccaaatc gaaaagggcc aggaggtagc cattttggaa tcgatgaaaa tggaaatccc
    15121 gatcgttgca gatagaagcg gaatcgtaaa agaagtcaaa aaaaatgaag gcgactttgt
    15181 aaatgaagga gacgtactgc tcgaactgag cgattccact caataatttg gaggaagacc
    15241 atgtcatatc ctaaaaaagt gacaatcaaa gaagtcggcc cgcgtgacgg cttacaaaac
    15301 gagcccgtat ggatcgcaac agaggataaa ataacctgga tcaaccagct ttcccggaca
    15361 gggctttcgt atattgaaat cacatccttc gttcacccga aatggattcc ggcgcttcga
    15421 gatgctatcg acgtagcaaa aggcatcgac cgtttaaaag gggtaacgta cgcggcactt
    15481 gtcccgaatc aaagaggact ggagaatgcg cttgaaggag gcattaacga ggcttgcgtt
    15541 tttatgtccg ccagcgagac gcacaacaga aaaaacatca ataaatccac ttctgaatcc
    15601 cttcatatac tcaaacaagt aaacaacgac gcacaaaaag caaacctcac aacaagagcc
    15661 tacctctcga ctgttttcgg ctgtccgtac gaaaaagatg tccccattga acaagtcatt
    15721 cgcctttcag aagctctatt tgaatttggg atttctgaat tgtcgcttgg agatacgatt
    15781 ggagcggcta atcccgccca agtggaaact gtacttgaag ctcttttggc acgattcccg
    15841 gctaatcaaa ttgccctgca ttttcatgat acgagaggaa ccgctcttgc caacatggtc
    15901 acagcactcc aaatgggcat cacggtgttc gacggctcgg caggcgggct tggtggatgc
    15961 ccatatgcgc caggttcatc aggaaacgcc gcaactgagg atatcgtgta catgcttgaa
    16021 cagatggata tcaaaacaaa tgtaaagcta gaaaaactgc tatctgcggc caaatggata
    16081 gaagaaaaaa tgggcaaacc gctgccgagc agaaatttac aggtgtttaa atcatcttga
    16141 taaaagggag gacgcataca atgggagaat ctattctttt tactgttaaa aatgaacata
    16201 ttgcgttgat caccttaaac aggcctcagg cagcaaatgc tctttcagcg gaaatgctta
    16261 gaaacctgca aatgattctt caggaaattg aattcaattc aaacatccgc tgcgtcatcc
    16321 tcacaggcac cggtgaaaaa gcgttttgtg caggagcaga cctgaaggaa cggataaaac
    16381 tgaaagaaga tcaggttctg gaaagtgtat ctctcattca aagaacggcg gctttacttg
    16441 atgccttgcc gcagccggtc atagctgcga taaatggaag cgcattaggc ggcggactag
    16501 aattggcatt ggcatgcgac cttcgaatcg caactgaagc agctgtgctg ggacttccgg
    16561 aaacagggtt agctattatc ccgggcgctg gagggaccca aaggctgccc cggctgattg
    16621 gcagaggaaa agcaaaagaa ttcatttata caggcagacg cgtgaccgca cacgaagcaa
    16681 aagaaatagg ccttgtagag catgtcacgg ctccttgtga ccttatgcca aaagcagagg
    16741 aactggccgc agccatttct gccaacgggc cgatcgctgt ccgtcaggct aaatttgcaa
    16801 tcaataaagg attggagaca gatctcgcta caggccttgc gattgaacaa aaagcgtatg
    16861 aacaaaccat cccgacaaaa gacaggagag aagggcttca ggcctttcaa gaaaaaagac
    16921 gggccgtata caagggaata taaaagggag gcaatgctca tggattatga aaaggaacga
    16981 acagaacggg ctgaacggat tcgaaaaggc ggagcggaaa agtatcatca aagcaatcgg
    17041 gaaaaaggca agctctttgt cagagagcga ctttcccttc tctttgacga tgacattgag
    17101 ctagaagacg ctttttttgc ggaatgtatg tcagacgggc ttcccgctga cggagttgta
    17161 accgctatcg gcaaaatcgg cggccaaacc gtttgcgtca tggcgaatga ttcaacagtg
    17221 aaagcggggt catggggagc aaaaacagtt gaaaaaatca tcagaattca agaaaccgcc
    17281 gaaaaattaa actgtccgct catttattta gtcgattcgg caggcgcccg aattaccgac
    17341 caaatcaatg tctttccagg gagacgcggt gcaggaagaa ttttttacaa tcaagtcaaa
    17401 ttatcaggac gcattccgca aatctgtctg cttttcggac catctgcagc aggtggcgct
    17461 tatattccgg ccttctgtga tatcgtcgtt atggtagacg gtaacgcctc catgtattta
    17521 ggctcgccaa ggatggcgga aatggttatt ggcgaaaaag tgtctctcga agaaatgggt
    17581 ggcgcccgta tgcattgctc aatctccggc tgcggagata ttcttgcaga aactgaagaa
    17641 gaagccatac agctggcgcg ggcttatttg tcttactttc cggcaaattt tcaagaaaaa
    17701 gcgcccattc atgagaaacg cccgccaaaa cacttcgaca ctccgcttgc cgacgtcatt
    17761 ccgcaaaatc aaaacgcgcc ttttgatatg catgagctga ttgagcgggt catagatgaa
    17821 gactcatttt ttgagatcaa agccttattt gcaccggaat tattgacggg cctcgcacga
    17881 ataaacggac agcctgtcgg cattgttgca aaccagccga aggtaaaagg aggcgtctta
    17941 ttccacgatt cagcagacaa agcggctaag ttcattacct tatgtgacgc ttttcatatc
    18001 ccattgctgt tcttagccga tatccccggt tttatgattg gcacaaaagt agaacaggct
    18061 gggattatca gacacggagc gaaaatgatt tctgcgatgt cggaggcaac tgttccaaaa
    18121 ctctctgtca ttgtccgaaa agcttacggg gcggggttgt atgcaatggc agggccggca
    18181 tttgaaccgg attgctgtct agcgctccca accgcccaaa tcgccgtcat gggccctgag
    18241 gccgctgtaa acgctgtcta cgctaaaaaa atcgccgagc tgccagaaga agagagagcc
    18301 gcatttatca gcagcaaacg ggaagaatat aaagaggaca tcaatatcta ccgtctggct
    18361 tcagaaatga tcattgatgc tgttatccca gccaattcgc tgcgtgatga gctggccaaa
    18421 cggctcaagg catacatgac aaaggaaatg acatttacca atcgaaagca tccggtttat
    18481 ccagtgtaaa agcaagaact taggagcgca aaaaaagcgc tcctttatat atttacaata
    18541 acaacattat gtaaactaat taccattgca taaaacgctt ggttttttag aatagtaaat
    18601 aaaggctgcc gcacctctag cggcaattgt cagtttatca taaaaagggg cctacattat
    18661 gtatcattta tattcacata acgacttgga cggagtaggg tgcggaatcg tagcaaaatt
    18721 ggcgttcgga aaagacgtag aggtccggta taactctgtc aacggcttaa acgcacaggt
    18781 gcagtacttt ttagaaaaag cgaaggagag caacagacag gacacgttat tcatcaccga
    18841 tctcgccgtc aatgaagaaa acgaagagag attgaatgag tatgttcatg cagggggcaa
    18901 agtgaagctc attgaccatc ataaaacagc ccttcatttg aatgagcatg aatggggatt
    18961 tgtccaggtg gaatacgatg atggaaggct cacatccgcg acatcgcttt tatatggcta
    19021 tctcgttgaa aatggcttca tgaaaccgac aaatgcctta gatcaattca cagagctcgt
    19081 ccgccaatac gatacatggg agtgggagcg gtacgatcaa aaacaggcaa agcggcttaa
    19141 tgatcttttc tttttgctgt caatcgatga atttgaagca aaaatgatcc agcgcctttc
    19201 cgcgcatgac gaatttttct tcgatgattt tgaagaaaaa ctgcttgatt tagaagacga
    19261 aaaaatcgag cgctacctcc gcagaaagaa aagggaaatg gtacaaacct ttgttcacga
    19321 acactgtgta ggcatcgttc acgctgaatc gtaccattca gagctgggga acaggctagg
    19381 gaaagataac ccgcacctcg attacattgc gattttgagc atggggtcaa aacgagtcag
    19441 tctccgcacc attcatgatt acatcgatgt gtcagaaatc gccggccgat atggcggcgg
    19501 agggcatgca aaagcgtccg gctgttcaat aaccgatgaa gtatacgagt tgtttgtagc
    19561 tgaagctttc cgttttgatc ctgtacggcc ggatgccttc cgtaacatct ataatctaaa
    19621 gggatctgcg aatggatcat tatatgaaaa tcgcgcacaa atgagatttt ttcttttccc
    19681 tttagacaat gaatggaata ttcaaattaa cggagaaacc caagacgaaa cattcgcagc
    19741 gtttgaagag gcagaatggt ttattaagag aaattatgcg gcatcgctcg tgcgggatga
    19801 agtgtttgtc gcatttttag cggagaatct gaagctggca aatcaacatc gcaagtaaaa
    19861 aaatatgcat aggggagcgt cagtcacccc tatgcatatc cgctagctat cgtttaaata
    19921 tggctgtacg tttcttaatc acaaaataaa gggctatcac gacaacagcc aatatcataa
    19981 tcggtgttgt ataagtgccc gctatattct caacatcatc ccactggctt cctagctgta
    20041 tgcctaaata aacaaacaaa atagaccatg gaatgatagc aagcacagtc agtaccacaa
    20101 atttgagaaa aggcattctg gcaatacctg ccggaatgga tatggcatgt ctgacaaccg
    20161 gtataaaacg agccgagaag acaactccgg caccgtattt ctgaaaccag ttttccgaca
    20221 tgtcgatatg atgcttttta atcaataaat acttcccgta tttgtccaga aatggcctgc
    20281 cgccatagcg accgatccag taaataaaga tctgggcaat ggtacccccg ataacacccg
    20341 caataattgc gccaataaat ccaatcgtgc cttccgatac catatagccg ccataagcta
    20401 atacaatctc actcggaatg atttcaatca ttaacccaat cgcaataccc gcatatccca
    20461 tgttcgtcag ccatgttaaa atttcgctta tcaaactgcc cacattcttc acaacctgtc
    20521 ctaatctttt tcactattat atgactgatt gacgagcaag atggttacaa tttttttacc
    20581 gcagcatttc tttcgtttcc cgtttgatca catcttctaa ataggccaaa agctgagatc
    20641 tcatttcgga acgcattaag ccgatttcgg tgctcgcttt aaaacagcct agcttatcgc
    20701 caatgtcata tcgatttcct tccagcagcc gggcgtggat cggctcctta cggcaaacct
    20761 cacgaagcgc atctgtcagc tgaatttcgt tgcccgcgcc tctgccaatt gtcttcaaaa
    20821 cggagaagat cgaagaattc agcacataac gtcccattac tgcgatttcc gaaggtgctt
    20881 cttcaggaga aggcttttcc actaaatcgt tcacttcata tacatgccct tgagaccctg
    20941 atgtatttat aataccatat ttgctgacat cctcagggag aactgactgt acaccgacaa
    21001 cctctgtgcc ataaacgtca tatacatcca ttaattgccg aagagccggt gtttcagaca
    21061 ccataatatc atcacctaag agaacagcaa aaggctcatc tccgataaaa tgctccgcac
    21121 acagcaccgc atggcctaat ccgagcggtt ctttctggcg gatgtaatga atattggcca
    21181 aatcggcaat ctgctgcatt tccttaagtg tctccgtctt gcctttttca cggagattga
    21241 attccaattc cgccgatcga tcaaaatgat cttcaatcga gcgtttgttt ctccctgtaa
    21301 taatcagtat atcttcaatt cctgactctg cggcctcttc tacaatatat tggattgccg
    21361 gtttgtcgac gattgggagc atttctttag gctgcgcctt tgtcgccggc agaaatctcg
    21421 ttcctaaacc cgctgcggga ataaccgctt ttctcacttt ttttctcatt catcctcact
    21481 cctgatcctg tatgtttttc atcgaatctc caaataccca gattcggttt ccgataaaat
    21541 tcatcatcat tccgccgata gtggcggcga gcttactcac caaaagcgag cagccgcaat
    21601 tttgaaacaa ataaagcagc aaaaaggtga tccccgacgc ggcaatatta atcatgagaa
    21661 aacgcacgat ctctttcccg tcagccttac gtttcacaca aaacgtccaa ttccggttcc
    21721 acacatagct gttgacgata cctgcagtat aggagcagat ctgcgccggc agataagaga
    21781 catgacaagc ggtaagaaga aagaagacac caaaatctat cagcgtattg ccgacgccta
    21841 cggtgcaaaa acggcctaat gtctttattt tttctttcag cgtaacggac ctcccttcat
    21901 aaaagatgcg agtggcagtc atatttgttg atatggatta ctatagcgga cagtgttgaa
    21961 taaacaatta ataaaatatg aacaaaacat gaaaaagcgg gtataccgct caatagtctt
    22021 atactcttga aaaaaacagc cgcattgaac ggctgttttt tgtgtctgaa aacatacaaa
    22081 tataaacgga gtgagcccca tcttatcaat gaataaatgt atccagttcc tttgtagaat
    22141 cgaacactaa ctcctccaaa agtttctata cacaattttt ttaatgatgt aggatgttag
    22201 ataaaggaat atcttggata atgatgtaat ctccgttcaa tgtgattagt gggaggccat
    22261 gaacaatcct gtctttttat tttctggaca atggtcgcta ggaatgggga aatttttttg
    22321 aacaattttg aaggagtggt gcgatctcct cgaagaaagg agagaatgga gacacatgaa
    22381 gatgagcttt cagaacaaga actgggaaca ttgctaaaca gcttccggct accttatgcg
    22441 tgcgatcttc atgacctgtt gtcatcaaat tccaaaagaa aatcccccat tttaaggaaa
    22501 aaggaggatg tgaagtgatg agaaaaaagt gtagcgtatg tttatggatt cttgttttac
    22561 ttttgagctg cttagctgga aagtctgcgt atgctgccac cagtagtaca attgcaaaac
    22621 atgtagggaa ttcaaacccg cttatcgacc atcatttggg cgcggatccg gttgcgctga
    22681 cctataacgg aagagtctac atctatatgt caagtgatga ctatgaatat aatagcaacg
    22741 gaacaattaa agataattca tttgccaatt tgaatagagt attcgtcata tcttcagcgg
    22801 atatggtgaa ctggacagac cacggagcca ttccggtagc aagtgccaat ggagctaatg
    22861 gaggccgtgg gattgcaaaa tgggcaggtg cgtcatgggc accgtcaatc gcagttaaaa
    22921 aaattaatgg caaggataaa ttcttccttt atttcgcaaa cagcggcgga ggtattgggg
    22981 ttctcaccgc agacagcccg attggtccgt ggaccgaccc aatcggaaaa ccgctcgtaa
    23041 cgccaagtac gccaggaatg tctggtgttg tatggctttt tgatccggca gtatttgtag
    23101 atgacgacgg aaccggttac ctgtatgccg gcggaggcgt tcctggcggt tcaaatccaa
    23161 cgcaggcaca atgggtcaat cctaaaacgg ctagagtcat aaaattgggg cctgatatga
    23221 cgagtgttgt tggaagtgca tctacaattg atgcgccttt catgtttgaa gattcgggat
    23281 tgcacaagta taacggaaca tattattact cctattgcat caatttcggc ggcacgcacc
    23341 cggccgataa acccccgggt gagatcggct acatgaccag ttcaagtccc atgggcccct
    23401 ttacatatag agggcacttc ctgaaaaatc cgggtgcatt tttcggaggt ggcggaaaca
    23461 accatcatgc tgttttcaat tttaaaaacg agtggtatgt ggtgtaccac gcgcaaactg
    23521 tcagttccgc tctgttcggg gccggcaaag gataccgttc tccccatatt aataagctgg
    23581 tgcataaccc agatggatcc atccaagagg tagcagcaaa ttatgcaggt gtaacacagc
    23641 tttccaattt gaatccttat aaccgggtag aagctgaaac gtttgcttgg aatggacgca
    23701 ttttgacaga gaagtccaca gcacccggcg ggccagtaaa taatcagcat gtaacaagca
    23761 ttcaaaatgg agactggatt gctgtaggaa atgcagactt cggagcgggc ggtgccagga
    23821 catttaaagc aaatgtagca tccactttag gcgggaaaat agaagtgcgc ctcgatagtg
    23881 ctgatggtaa gcttgttgga actctgaatg taccttccac aggtggagcg caaacgtgga
    23941 gagaaataga aactgcagta agcggggcaa ccggtgtgca caaagtattc tttgtattta
    24001 ccggaacagg tacaggaaac ttatttaatt ttgattactg gcagtttacg caaagatagt
    24061 actcgtaatg ggccgcttaa aaacgaggcg ggtgaagtac gagccagcac cgggacagcc
    24121 cgccattatg gatatgccat gcagattttt taataccgta aaagacacat gacgaaggag
    24181 agaaataaat gattccacgc ataaaaaaaa caatttgtgt actattagta tgtttcacta
    24241 tgttgtcagt catgttaggg ccaggcgcta ctgaagtttt ggcagcaagt gatgtaacag
    24301 ttaatgtatc tgcagagaaa caagtgattc gcggttttgg agggatgaat catccggctt
    24361 gggctgggga tcttacagca gctcaaagag aaactgcttt tggcaatgga cagaaccagt
    24421 taggattttc aatcttaaga attcatgtag atgaaaatcg aaataattgg tataaagagg
    24481 tggagactgc aaagagtgcg gtcaaacatg gagcaatcgt ttttgcttct ccttggaatc
    24541 ctccaagtga tatggttgag acctttaatc gtaatggtga cacatcggct aaacggctga
    24601 aatacaacaa gtacgcagca tacgcgcagc atcttaacga ttttgttacc ttcatgaaga
    24661 ataatggtgt gaatctttac gcgatttcgg tacaaaacga gcctgattac gctcacgagt
    24721 ggacgtggtg gacgccgcaa gaaatacttc gctttatgag agaaaacgcc ggctcgatca
    24781 atgcccgcgt cattgcgcct gagtcatttc aatacttgaa gaatttgtcg gacccgattt
    24841 tgaacgatcc gcaggctctt gccaatatgg atattctcgg aacccacctg tacggcaccc
    24901 aggtcagcca attcccttat cctcttttca aacaaaaagg agcggggaag gacctttgga
    24961 tgacggaagt atactatccg aacagtgata acaactcggc ggatcgatgg cctgaggcat
    25021 tggatgtttc acagcatatt cacaatgcga tggtagaggg ggactttcaa gcttatgtat
    25081 ggtggtacat ccgaagatca tatggaccta tgaaagaaga tggtacgatc agcaaacgcg
    25141 gctacaatat ggctcatttc tcaaagtttg tgcgtcccgg ctatgtaagg attgatgcaa
    25201 cgaaaaaccc taatgcgagc gtttacgtat cagcctataa aggtgacaac aaggtcgtta
    25261 ttgttgccat caataaaagc aacacaggag tcaaccaaaa ctttgttttg cagaatggat
    25321 ctgcttcaaa cgtatctaga tggatcacga gcagcagtag caatctacaa cctggaacga
    25381 atctcactgt atcaggcaat catttttggg cccatcttcc agctcaaagc gtaacaacat
    25441 ttgttgtaaa tcgttaagag cacaaagaca cacaaaaata atagagtgtc tgaattggcg
    25501 atttttccga ttgggaaatc gcttttttat tttgttgctg aattacagga agaagaaagg
    25561 atgtacataa aaacagtaaa gctttaatct tcatcttttc tagtttacat aatatatatt
    25621 ctaggaagta agtgaaataa ataaatttct gtctcaatat caaagtatac ttaagttagt
    25681 gagacagaaa ttaaaatttt tctgctgaat gacaaatcaa aaaaatggcg ttgtcaatcc
    25741 ataataaacg gcttctaaat cctccagcgt catatcgcca tatgcgcatt tgataacaga
    25801 gtcagcaaac acatcatagt cataatctgt agaaaatcct tgctgcagct gtttttcgta
    25861 aacttcgatc tgatcttttt gatgctggat gtctttttcc ttacctggat agtccggacc
    25921 atttatcaca ttactcattt ctttgtacat caccatatac tgtttcagta tttcatccac
    25981 aacgcaaacc tcctattaga tgataaaaac ggacatcgtt actgatgtcc gccaaaaaaa
    26041 aagcttaact aaattggttc tgttccccaa atcagttttc ctttatcata taatgtgatt
    26101 tttttcgttg ttttaaacgt atttgatttg aaaaaggaat aatcgccgct ttgtgcataa
    26161 ttgctccagt catcattgtg aagacgaagc tgaatattcc ctgtgcttgc tcccggtgcc
    26221 agcgttccgt ttttaaaccc aagttccaga taggtatctg caccttgctt tggtttatgc
    26281 aacgtcacaa acttgtgtgt catattgccg catccaagct gcgcgtagtc acagtcaaaa
    26341 ttttggcctt tgtttttcgc gttataccag taacgagcag tgacatcttt taaatcaacc
    26401 gtggtattgc cgttattttt tatttgaagc tgcggacgga tttggttgct gttcataccc
    26461 ccatcccctg ctctgtattg tacagaaata ccgttttcct gtgtgggttt atcttttgct
    26521 ggcgtttcag gaatgccctt cgtcgaatct ttggtgccga gaatgttttc tctaacgaat
    26581 gttcctgaag cagataaatc tgacaaccgc cagccgcctg ttttagatgc ccccggcttt
    26641 aaagctgagg atgattcctg cttatcagaa agattccagt tcacccagct gatggtcttg
    26701 ctgtcgagat atttcagcca ttccctcgat tgatcaagga atacaccgcc attgccagac
    26761 gcgtcgcttg ttccccattc tgtcacaaaa ataggtgctc ctttgctgag tgcatagttt
    26821 gctttatccc gtaaaaactg gccgtgagta ccggcgtaaa aatgaagtgc gtacataacg
    26881 tttgcatctt ttagctggtc atcagcagca tcatttacat cctggctcca tgtaccggtt
    26941 ccgacaatga tgatgttgtc tggatcattt ttgcggataa cggaaatcac ttcttccgca
    27001 tacggtttaa tatcacgctt ccagttcaca tcaccgtttg gttcgtttgc aatttcataa
    27061 atgacgtttg gcgtgtttcc gtaaaggctt gacatttcct tgaagaattc ttttgccttc
    27121 tctttatttt ggtttggatt accgtcattt aagatatgcc agtcaatgat gacatatatc
    27181 ccaagctctt ttgcagcttc aaccgcttct ttcactttat ttttcacgga cgggttatca
    27241 atataaccgc catctgccgt atacatcgct gcacggaaaa cggtgatacc ccaatcgtcc
    27301 ctcagccatt ttaagctgtc tttattgaca tattctccat accattgcaa tccgtgtgaa
    27361 ctgatcccct tcagctgtac cgctttaccg tctcggttaa cgagctgtgt accttttatg
    27421 ctaagctggc cattcttggc tactggcgtt tttgtccctg ctgctgatgc cggcgaagcc
    27481 attatgccgc tcattgtcaa taacgtaatc aataaacacg taataaaaat agagattgac
    27541 cgtttcatat ctgatctttt cctccttcgc atcattttgg ctcttcactt cttatgagca
    27601 cgaactcatt gtaaaaatct ttctcatgat tgtctatcaa cctaatttct tgtttttggg
    27661 aggtttaaaa gcctgtcaat ttgctctatc tccattgaat aagacacaca tgacacatat
    27721 acaacaaaga aaactggact gaattgggac tttacacgtc atttttcctt cgagtcgaaa
    27781 aattaaattt atttccaata atgaaaaagc tgcattcaac tattgaatgc agctttgttt
    27841 tacatttata ttatgcttct tgttcatctt cccatgtttc agcgtttttc agccctggga
    27901 tgtttttcgc tttaaacaca ggatcaagtc cttgcttacg ctgtttcgca taatctttat
    27961 acactttgta agcaacgttt gacagcagcg taatcacaat taagttgatc agcgccatga
    28021 tacccataaa gaggtccgcc atatcccaaa cgatttggaa gcctgataaa gatccataca
    28081 caaccatagc aattacagcg atacggtaaa tgttcagcca tgttt
//
