LOCUS       gnlProkkaLCAHIECF_8    21612 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LCAHIECF_8.
ACCESSION   gnlProkkaLCAHIECF_8
VERSION     gnlProkkaLCAHIECF_8
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 15:19:46
            Original ID  :: gnl|Prokka|LCAHIECF_8
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 161863
            Orig. end    :: 183475
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(204..3890)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134:flavodoxin (Score: 80; E-value: 1.9e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_160"
                     /transl_table=11
                     /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQAHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRQTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYITTVFDLILANYGVNRGIGKRSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAVTPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     CDS             complement(4086..4562)
                     /locus_tag="ctg8_161"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDSRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     CDS             4706..5425
                     /locus_tag="ctg8_162"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMAKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFFIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRTFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     CDS             complement(5456..6172)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1133:Transcription regulator, crp (Score: 123.5;
                     E-value: 1.2e-37)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_163"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESINRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     CDS             complement(6271..7500)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 105.5; E-value: 4.2e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_164"
                     /transl_table=11
                     /translation="MIRLIIESLKGASQMINRQHIQLSLQSLSLVAGFMVWVLISSLIS
                     QITLDIHLSKGEISLVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWIS
                     IADSLFDLIAGGFFLGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAA
                     PVIAQAVGWKSTVQMYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLS
                     LFYFITFGAFVAFTIYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSP
                     LRILMFVFAGLTLSGIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGI
                     ANGIVSAMGGLGGFFPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKT
                     HTERNSQSIN"
     CDS             complement(7594..9264)
                     /locus_tag="ctg8_165"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             complement(9261..9689)
                     /locus_tag="ctg8_166"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             10001..10132
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_167"
                     /sec_met_domain="Subtilosin_A (E-value: 1e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg8_167_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="ctg8_167_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     CDS             10266..11612
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_168"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1079.1, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.8e-30,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.8e-08, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-22, bitscore: 75.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.7e-11, bitscore:
                     37.6, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 6.1e-10, bitscore: 34.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKKKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSTLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             11625..11786
                     /locus_tag="ctg8_169"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             11783..12502
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 127.7; E-value:
                     9.5e-39)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_170"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             12495..13805
                     /locus_tag="ctg8_171"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQSKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLMSGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             13771..14955
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_172"
                     /sec_met_domain="Peptidase_M16_C (E-value: 4.8e-06,
                     bitscore: 21.6, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAHLKEQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVYALMKT
                     FADLSFPSSLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFLDATDFIVDLVSQQKQLNILGQVQACDVWGHAPQTSAVTSGRIPVNRH
                     VFETETRSAAGPSVLTIGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTEERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             14960..16240
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_173"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.9e-14, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAQRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPSCPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLSIKLYWDIA
                     ARILFQLDSPFFQEIQQTYLLEIDRLSAETYIYEDGGFLILHSQGIHSSAYIDVASYYV
                     TQKKEQAAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHTIQDMDTQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     CDS             16237..16938
                     /locus_tag="ctg8_174"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGSVQAVSEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILGAIQQIGSFIYKR
                     FSYRSTASLDL"
     CDS             complement(16944..18320)
                     /locus_tag="ctg8_175"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSGRCPDFSQITVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVYTANTGDSTVSVIDADLNTIVKTIPFSAVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     CDS             complement(18360..19715)
                     /locus_tag="ctg8_176"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLILTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHSVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAVYVIGIDTLTVDRSIPVEG
                     YDVAIDPNGLFAYVLNFGIVQKVDLTTGEVTGTIERELIVSTIETNWPERYAYVLEQEF
                     FFNYLTVIDLNTFTISSTQELEYEGEYRMFTSGAEVYLYDGFTGNLYSVSLNGAGVIGN
                     VPQSARDFAFTPNGEFLYATHVLEQSITVYNTDDYSVETVISLGVSPGAIAI"
     CDS             19945..21090
                     /locus_tag="ctg8_177"
                     /transl_table=11
                     /translation="MTGAISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     CDS             21074..21193
                     /locus_tag="ctg8_178"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITVEVSNSSTEHFDVAQRAMI"
ORIGIN
        1 ttcctttttt caatgtccag cctcctttat atttgtcctg gtcctcccat tgcttcgggt
       61 agccgatgcc cggctttgtt tctacattat tgaagtacat atattccgca ccggaacggt
      121 ttgtccacgt gtttttgcag gtgacgctgc acgtgtggca gccgatgcat ttatccaagt
      181 tcatgaccat accgatttgc gctttaatct tcaagccaat cgacctcctt cagcttgcgg
      241 atgacgacgt tcaggtcgcg ctgattcccc gttggaccgt aataattaaa gccgtagctg
      301 agctgggcat agcccccaat catctgggtc ggcttgacgt gtatccttgt agggctgtta
      361 tgggtgcctc cgcggttatt cgtcagcttt gttcctggca cgttaatgtg gcggtcctgg
      421 gcatggtgca taaacgccat tcctttagga atccgatgag acaaaaccgc tctcgcgacg
      481 acaacaccgt ttcggttaaa gcattcaatc caatcgttgt ctttgatatc cgtgtcctct
      541 gcatcatctt tattcatcca cacggtcggc ccgccgcgga acagcgtcag catcggcaga
      601 gaatcaaaat acatgctgtg gacagaccat ttattatgcg gcgtcaaata attgaggacg
      661 atttcttttc cctcttgatc aggccgcttg ctcagaaacg ggcgatgctg gaggatcggt
      721 ttgaatgtcg ccatcgtttc accgaattcc atcatcagtt catgatcgac ataataggat
      781 tgtctgcctg tcagcgtccg ccacggaatt aatttttcaa catttgttgt aaacggcgaa
      841 tacctgcgcc ctcctttttc agagccggaa aacgctggag acgtgatcac cgttttcggc
      901 tgggctgtaa tttgttcgaa cgtaaagcat tcttcctcgc gttcttccgc caggtctttc
      961 agcttcaggt tcgtgatgtt ttcaagtgat tcccatgctt ttactgcgac ctttccattc
     1021 gaagtggatg atagggttaa aatcgcttct gcagcctgct ttgcttcact tatattcgga
     1081 catccctttg cgacactgtc cgaggtgatt tctcccaatc tctgtttgag tgattcatat
     1141 tcatcggcta ttgaccagct catccctttt gttccgctcg gctttaaagc aacgttcgga
     1201 ccaagtgcag tcattttatg aaaaatgtgt ttgtaatccc gttcaacgac ttggatgttc
     1261 ggcatcgttt ttcccggaat ggcttcacat tcgcctttgc tccagtcatt gattttgccg
     1321 aatggctggg ccaattcctg catggtgtca tggaggagcg gcgtcgcaac cacttctttc
     1381 acgggctcca tatcgacttc ttctgccaga tcggaaacgg cttttgacag cgccttgaaa
     1441 atatcccagt ctgacttcga ttcccacgga gccgagatcg caggagcaaa tggatgaatg
     1501 aacggatgca tatctgtgct gctgagatcg tgtttttcat accatgtcgc cgccggcagc
     1561 acgatatcgg aatacagcgc cgtaccggcc attcggaagt caagattgat taacaagtcg
     1621 agctttcctt ccggcgcctg ctcccgccat ttgatttctt cagggcggat gctgtcgcta
     1681 tcgtcattca ttaaaccgtt cgtcgtcccc agcaaatgct tgagaaaata ttcatgccct
     1741 tttcctgagc ttgagatcag atttgcgcgc catacgaaaa gatttcttgg gaaattcact
     1801 tcattatcag gatcttcaat cgcgaatttc agttttttct cttggagctg tgaggccacg
     1861 tacgcaccta cgtcttcggg tgttacggcc cctgcttttt cagcttcttt atacagatcg
     1921 atgccatttt gattgaaagt cgggtaagac ggaagccacc ccagccgtgc cgccagcaca
     1981 ttgtaatcag cgtggtgctt gtagcgggat gacgcagcaa tcggtgatgc caaatcactg
     2041 atcggctggt cctcataacg ccactgatct gtcgcaaagt agaaaaatga ggtgccgttt
     2101 tgcagcttgg gcacgccttc ccagtccttt gcagttgcaa tcgtctgcca cccttcagca
     2161 ggtctgagct tttcctgccc cacgtaatgg gcccagcctc cgccgtttac gccttgggcg
     2221 cctacaagca aaacaagatt taacaccgct cggtagatcg tgtcggagtt gaaccagtgg
     2281 ttaatgccgg cccctacgat aatcatggac cggccgtctg tatcgatcgc attttgggca
     2341 aactctctgg caatcttaac aacagcttct tttttgattc ctgtcatttg ttcctgccag
     2401 gcaggcgtaa acggctcagg atcatcatag gagacagccg atcgtttacc gatgccccgg
     2461 ttcacgccgt agttagccag tatcaagtca aacacggtcg tgatgtacgt ttcttcaccg
     2521 tttaggttca tttttttaat aggaagatcc cgctcgagca ctttgtttcc gtcatttgaa
     2581 aaatacggga tgcgcaccgt gccgatttcg tcctctattc ccagcacaga gagacggggt
     2641 tcaatcggtt ccccggtttc ttcatcaatc atgtgcaggt tccatttctg ttgcccgtcc
     2701 cagcgcgagc ccattgtccc ttggggtatg gcaaatgaac ttgtctgttc atcccaaacc
     2761 gcaggcttcc actgatcatg ctttgtctgc cgcccgatgt ccttcgcatg cagaaaccgt
     2821 cccgctgtgt atacgccatt ttcttttgac agggtaacga gaaatggaaa atcagtgtat
     2881 tgcttcgcgt actcaataaa acgttcagtt tcttggttca cgtaaaattc ctgcaaaatg
     2941 acgtgaccca tcgccatcgc aagcgccccg tcagtccctt ggcgaatact cagccagtca
     3001 tccgcgaact ttgaggattc cgcaaaatcc ggactgatcg aaatgacctt agcgccttta
     3061 tagcgggcct ccgccaaaaa atgtgcgtca ggcgttctcg ttaacggaac gttggagccc
     3121 catgtgatga tatagccgga attgtaccaa tcactgcttt ccggaacgtc cgtctggtca
     3181 ccccaaattt gcggggatgc cggaggaaga tccgcatacc agtcataaaa actgagcata
     3241 gggcctccga ttaacgacat aaaccgggag cctgatgcat ggctgatcat ggacatggcc
     3301 ggaatcggag aaaaaccgac gtttcggtca ggcccgtatt tcatcactgt atacagcaga
     3361 gaggctgaaa tcagcttcag cacctccggc cattcagcgc gcacaaaacc gcctttccct
     3421 ctcgcctgtt tataggactt cgctttttca gggttttcga cgatcgattt ccaggcttcc
     3481 aatggatttt gatgcgcctg cagtgcctcc cgccataaat tgatcagcac accgcgcacg
     3541 tatggatatt tcacacgcag cgggctgtag atataccatg aaaaactggc cccccgcggg
     3601 cagcctctcg gttcaaaatc aggcatatcc gggcctgttg atggataatt caaattttgc
     3661 ccttcccacg tgacaattcc gtttttgaca taaatattcc agctgcaaga ccctgtacag
     3721 ttaacgccgt gggtggagcg aacgactttg tcgtactgcc atctgtttct gtatacattc
     3781 tcccaatcgc gatcttcgcg ggtggtttgg ctatgtttat ttgaatggtg ttcgatagga
     3841 gagaaataat tcaatctcct aaacaacgga ctccttttct ttttcttcat gagagttcac
     3901 tccttccgag tcaggtgatg ctaagttcac tataaacaga gacagcgtgt ttccttgtga
     3961 actatgtcac acactctgct tttttcacaa aatgttcaca caaaggagaa ggaaggctga
     4021 gttcaggcag gacgcttggg tcattagctg cctttcattc aaagatcaaa aaaaaccggc
     4081 tctatttaag aaccgggctc agcgttttca tcctgtgatg tatgcagata ccgcaaaaat
     4141 aattgatagg aacaaaaaac attttgctga agcatagcca aaaagttcat ttgcagctgc
     4201 ggatgataag acatcatttt cttaaatatg taatatggga tgttgagaat cagaatgtct
     4261 gaagtggcat tgactgagat aaagggcgat aaataaagcc cgcctttttc atcaatcgga
     4321 aacacatcgc ctttttccca cagcgcaacg gttttcgacc cttcagggag cctgctgtcc
     4381 atgaaacgga cactgccttt taatacaata taaacagatt gagaatgaag aaaagatgga
     4441 gactgatcac atgagccgcg gataaacgtg ccgtttttca gcaaggtttc gacaatggat
     4501 agaggcactt cattaaacat aggaagttgt ttcagaaata ataaatagtc acactgattc
     4561 ataggaaaac ctcctgtgct aaggatagct ttagtgtagc tcgactgagc ctgtacagca
     4621 gtgatgtatt tcacagcctg tatgatgaat gtcacttatc aggagggtga ctgcatttat
     4681 aatgatagaa aaaaggagga tttcgatgaa ggcgctgatt ccgaagcagc acggcgcgtg
     4741 ggcgatgctg ctgatcccat ttttactcgg catggccaag ggaggccccg ttatttggca
     4801 tattccgctc ttcctaggct ggcttttcct atacttagcg gtttatcccg ttacgcttgc
     4861 cttaaaaaag aaacaaagca aaccatatca aaagtggatg tgttattacg gttttcccgc
     4921 ctgctgcttt ttgatgatct cggtctttca taaaccgcct ctcatctggg tgggcgtttc
     4981 tttactgccg ctgtttttca tacatatgta ttttgcccgc cgaaaaaacg aacgggccct
     5041 attgaatgat gttgcaggtg tcttgttctt ttgttcgggc gggtttgcga gctgctggct
     5101 ggggatggga accctcgacg gctgggcttg gtttattttc ttgcagtctg ctttattttt
     5161 tatcgggagt tccttttatg tgaaatcggt gattcgtgaa agaaaaaaca ggacatttgc
     5221 atactggtca tggggatatc acctgctgct ccccttttta tccgctcttt tcggagcagg
     5281 atgggcgttt ctcgctttta tcccgagcag cttgcgggca tggttttttc atggaaggga
     5341 ttggcccgta aaaacgattg gcattctgga aatcgtgaat gcctgcttct ttcttgccgt
     5401 catgtgcctg tttatcacaa ggtaaaaaaa caaggacacc gctgtccttg ttttttcagt
     5461 caatattgca aatctccagc gggcaatttt cacactcaat ctcacatcgt aaatagtccc
     5521 gcttgtgcaa aataattttt ccggattcgt ctatcgaaat aacccctttt ttgcggagat
     5581 ctcccagcat acggttgatg ctttcccgtg cagccgcgca aaactttgcc aaatcctgat
     5641 ttgtcaggac aatgttaatc agaatgccgt cgcttcgctc cactccgtag ctgtttgata
     5701 aacggataag ggtggaatag agcgccccct ttttgccatg aagaagcaga tccctgattt
     5761 tggactgaat cttccggagg tgcgtgctca tccatttcat gaactcaaat gtcaaagcgc
     5821 cgttttggat taattctttt tccagcttat ttttattaat gacgagcacc tcgccatcct
     5881 ctagcacttt tgcactgagc atatacctcg gttcttcagt gaaaagtgtt aattctccga
     5941 cgatatcatg cttttggcag attctaagcg tcaggtcttt tccgtcagat gtcagcttgc
     6001 cgatttcaat gagtcctgat tgaatcagat aaagctcttc tgcatccatt ccttctcgaa
     6061 acaaatacgt gtgtttttcc atttttcttt tcgtgctgat cgattccagc aattcatgca
     6121 gatcgctgga aataagatca ctatcagatg gtcgaacaga gagaaaattc atgagctcac
     6181 ctcgaagaaa gtcacgttgt gtgtttattg taacgtgaat tgatttgtac ccatcgagaa
     6241 aaaactaaca atcttgtgaa tgccccagtg ttagttgatg ctctggctgt ttctctccgt
     6301 gtgtgttttc attctttcct gccaatacat ccatatgaca aggacaaagc tggctaacgc
     6361 cacctctgaa agcgccataa acccgatcgc gtactggcct gttgcctgaa atacactcgc
     6421 caatatgagc ggaggaaaaa agccgcctaa accgcccatg gcagacacaa tcccattggc
     6481 aatccccgct tgcttcgaaa aatagaaagg caccagttta aaaacagttc cgtttcctat
     6541 gcctgagcag acggccacgg ttaatgatcc aaacgtataa aggccgattg tcggcgagaa
     6601 cgataggata atgcctgata atgtaagccc ggcaaaaaca aacatcaaga tgcggagcgg
     6661 gctcatttta tcagccagga atccgcctgc aggcctgagc agcgtagaaa ccgcaataaa
     6721 gccagccgtc cgcaagccgg catctgcagg attcagccca aaatgctcca ccagaaagtt
     6781 cggcagatag atagtgaagg cgacaaaggc gccgaacgta ataaaataaa acaggctcag
     6841 aaaccatagc acatgatttc ggtaaacggc tttgatttga gtcttaacag aaactttgac
     6901 cttcttctca tgcctgtcac cgaacaaaac gtgcagtaag gcaaagacag ccagcaaaac
     6961 cagatacatc tgcacagttg atttccaccc gacggcttga gcgataaccg gcgctgcaaa
     7021 tgtcgtaacg gctgtcccga tatttcctgc accgtaaatc ccattgacga caccgtgctt
     7081 ttctttcgga taatatttcg ggagggaggt cactccaatg gaaaacaccg ctcccccgat
     7141 ccctaagaaa aagccgcctg cgattaaatc aaacagagaa tccgcgatac tgatccaaaa
     7201 tacaggaaat aaaagcagga tgaagctgac cataaacatg agccgcgcgc caaacctgtt
     7261 cgttaaatac cctaaaggaa tgcggagaag cgatccgagg atcacaggaa tcgccgtcac
     7321 caaagaaatc tcacccttgc ttaaatgaat atctaatgtg atttgggaaa tgagtgatga
     7381 aatcagcacc caaaccataa accctgccac caagcttaat gactgtaacg ataattgaat
     7441 gtgttgacgg ttgatcattt ggcttgcccc tttcaatgat tcaataatca gtcttatcat
     7501 acaaaaactc ggcaaacagg attgtgaatt acatcacacg tttttctcat aaaaaaagga
     7561 caaagcccga agactttgtc cttttgatcg tgattacatt ttttccggag ccgatacgcc
     7621 gatcagctga agcgcattgt tcagcgtaat ttgcgttgcc ttcattaaag ccaggcgcgc
     7681 gcggctcttc tcttcatttt cagggtcgat gactttctct gcgttgtaga agctgtgcag
     7741 agcagaagcc agatcataaa tatagtttgt gacacggtgc ggaattcgtt tttccgctgc
     7801 ttccgccact gcctctggga agccgccgat cgttttcagc agatcgtatt ctttttctga
     7861 ttgaatatgg ctgaaatcaa gatctgccgc cggtttaagt ccctgctctt ccccttggcg
     7921 aagcatgctg caaatacggg catgcgcgta ttgtgcataa tacacagggt tttcgttaga
     7981 tgttgataca gcaagatcta agtcaaaatc catatgggtg tccgcactgc gcatcgcaaa
     8041 gaagtaacga acggcatcca agccgacttc ttcaatcagg tcacgcatcg ttacggcttt
     8101 accggtccgt ttgctcattt tcattttctc gccgtttttg taaaggtgaa cgagctgaat
     8161 gatttctact tcaagcgttc ctttttcata gcccagcgct tcgattgccg ctttcatacg
     8221 cgggatgtag ccgtggtgat cggcacccca aacgttgatc agcttatcaa agccgcggtc
     8281 aagcttgtcc ttatgatacg cgatatcagg aagcaggtac gtgtacgtgc cgtccttctt
     8341 gatcaatacg cggtctttat catcgccgaa cgtcgtggaa cggaaccaag tcgcgccgtc
     8401 ttcttcatag acgtggcctt tttcacggag cgcttcaagc gccttgtcga tttttccatt
     8461 ttggtacagt gaagtttctg aataccacac atcaaacggc acacggaagt tttccaagtc
     8521 cttacgaagc ttttccagct cgtatttcag gccgtattca cggaaaaacg cgaggcgttc
     8581 actttcctct tcgttaacga aacggtcacc gtattcctca gcgagacgct ttccgatcgc
     8641 aatgatatcc tcgccgcggt agccatcctc cggcatcggt ttttccaatc cgagtgcttc
     8701 aaagtaacgg acttcaacag aaagcgccag attgttgatt tggtttcccg catcgttaat
     8761 gtagtattca cggctcacat cgtaacccgc ttttgaaagc acgttgcaca aggaatcgcc
     8821 gacagccgcc ccgcgcgcat gcccgaggtg aaggtctccc gtcggattcg ctgatacgaa
     8881 ttctacctga actcgttcac cgtttccgat gttcgtttcc ccatatgctt cccctgcttc
     8941 cagtacagac ggaatcagct ttgttagata ttgattgttc atatagaaat tgataaaacc
     9001 cgggccggcg atatccagtt tttcaatcga agcctttcct ttatcaaaat gagcgacaat
     9061 ctcttcagcg atttgacgcg gcgctttttt tgcaactctt gccagctgca tcgccatatt
     9121 cgttgagtag tcgccgtgtg ttttatcttt cggtgtttct aaaacaacat tgggaatctg
     9181 gctttcttca gccagtcccg ctttcagaac ggccgcttta atttcttctt tcagcacgtc
     9241 cttcatttgt tccgcaatgt tcatgcgtga gttcctccct catacgtgat cgtcatatta
     9301 tgtaaatgct cctgctcgtc tccgacatgc atgtcatatg cgatgctgat acggcctttt
     9361 tcttcatcga gatcagattg aatcgatttt gtgcttgttt tcagctcaag ctcaccaaat
     9421 gacattttat atttagcaat tgtggaagct cccgttacga aacgctgatt cattttgaca
     9481 gcgcctgacc tcatgaccag gacttcgcct tcgcttactt tcacaatcgt tttgactttg
     9541 cctaagtcgt gttcttcata ataagataga tacactttat tttgttttac atagtaaaat
     9601 ccggtggtgc ggaattcgat gacttcttgg tttccgtcat cctcgatcac agacttcaca
     9661 tggagtgtta tcggtgtctc ttgcttcatt ctgacacgtc cttttcatca ttccactttg
     9721 acttgaatag tataatcatt cggtttgtaa acttcaactg cttctatctt accatcattg
     9781 ctcatcagat ttgaagataa acctcataaa aagcatttcc ttatatagaa gagaaaatca
     9841 tatcactaat tacctttagg aaatgttaca tttttccgaa atctatcatt tccttttcac
     9901 atttttttca aattatatgt attgaattag taatttgata gttttaagat aaaagtacaa
     9961 catagatctg ctagaaaaac aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggccctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacggctt acgagctttg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtt atccagcttg
    10561 gaaaccgggc cagccgccat acaatcacca cgagcggaag caatgaattt ccgatgcccc
    10621 tgcacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcgcc tgaagcgctt ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg cggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagtt tggagctttt gaagacttac aagaaaaaaa
    10921 tcatcgtcgg catttctctt gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcggg gcgaaggcgt tttcttacaa ttgggttgac gatttcggaa
    11161 gaggcaggga tattgtccac ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaaa tgtgattgat gagtttaaag atctgattcc gattattccc tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc actctcgtcc ataaactgtg gcaagcgcag gcgccgcggt
    11461 tcagcgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc gaaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggttgctt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 caggagaatt tcagagctgt ccttggggaa caggcaaaag gttgtattaa tgacaggctt
    12241 attgctgcgc gctcccctgt ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtc ttttatcaga aaatgcgcga gtactgtgaa gcaggcggga ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tatgcggcta ttcttcacaa
    12421 caaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 tgaggtgatc ggccatgaat aacataatcc ccatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca aggaaaaaag gacgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tgtttgaaat cgggctgatc cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatggt gtttctttct gtgacatctc
    12721 aatggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaact ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accatttcgt caaaaagaaa aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgcctcag tgccgctttg atgccggccg ccacgcttcc gctttgcgcg gtgcatatgc
    13081 tgtgggcggt gatcattgac tttcctgtct ttctgcaggc gcccccgcag cagagcaaga
    13141 tgcattcatt tatgcggcga tctgaatttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtgatggc ggcgttcagc ggcttctttt
    13261 cgttccagat gatgaacacc ggcatcttca atcagcaagt gatttatatc gtgatttccg
    13321 cgcttttgct catctgctcg ccgatcgccc ttttgtactc gattgaaaaa aatgaccgga
    13381 tgttgctcat cacgcttccg atcaagcgga aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct aatgtcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgtccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 ttatcaggtt aactgcggat gaaaaaaggc cctccttcag ctggcagacg gaacagcagc
    13621 tttggagcgg tttctcaaaa tatcggtctt atctattttg tcttccccta ttcttagcca
    13681 cattagccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatatcaa tcgccgcgag ctttctgaaa
    13861 ccgatcgaaa gcgcggcgga acctgaggaa gaaacgattt atttttacgg cgccgccgca
    13921 cacctgaagg agcaaatcat tgacgctttt ggttgtgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tcttttttga tcagcagctg aaaacctgcg ggacccgttt gattcaccca
    14041 ttatataacg ggaatcttca tgtttacgcc ctgatgaaaa cttttgcaga cttgtctttc
    14101 ccttcttctc tttcattcga agcagttgaa aaggccagga atgagctgtt gctgagaatc
    14161 gaaaagaaat tcactgatcc cttctcctac tcggcggcgc gcttggctga ggaggtcttc
    14221 ggaaacccga tgtacggcac aggcatgttt ggccggaaag acaggataaa ggcgattcat
    14281 cccaaacggt ttctcgacgc aacggacttt atcgttgatt tagtgtccca gcaaaaacag
    14341 ctgaacatat tgggacaagt acaagcatgt gatgtttggg gacatgcccc gcaaacgtcc
    14401 gctgtaacgt ccggaagaat acccgtaaac cggcatgttt ttgaaacaga gacacgcagc
    14461 gctgcaggtc cttccgtctt gacaatcgga tttgactgcg gagagatgaa agatgccagc
    14521 gattatatca aaatacagct aatagacgga ttactgggaa agtacggcca ttccgcttta
    14581 ttcaagcact tcagagagaa ggatctggca gtctatcacg ttatcacccg ttacgatgtc
    14641 atgaacaatt tgctgcttgt ttcaatatgt acagatcagc ttcatgagaa agacattccc
    14701 ccgcgcgttt tggaagctgt ctcagctttt catacagaag agcgggaact agaacaggca
    14761 aagcagtttt tacgcaatga attgctgctg caattcgatt ctcccgaagg tctattggcc
    14821 tatatgggga tcctgcgccg cttctcctgc acgaaagaag ccttgctgga tggcatctca
    14881 gcggttacat gccgcgatgt attgcaattc atagcgacca tcaattatat cggagctcat
    14941 gtagtaaggg gatgaagaga tggaaaagaa agcctttttt caacagctgg atgaacgaac
    15001 cgatatcaga tacacagaca gcggactaaa aatattcaga ttgaaattcc cccgcgccca
    15061 cctgcggctg tgcaatgtaa aaatcgattt tggaagccgg gatgtatgta tacgggcaga
    15121 atccggtgat acactgcttc cgtatggcac agcgcatttt ttagagcatc ttcttttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaacgcatt
    15241 cactacctac acagatacca atttcatgtt tacctcatta ccggatcggc tcagacaaac
    15301 gatccccatc ctgcttgatg ctttatggaa ccactcattt gacaagaaga ttgtcgctca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac cttaaccatc agctctcata
    15421 tcattatcag ctgatcagca tgctttcgcc ctcctcacca gctgccgttt tccccgcagg
    15481 cagaatcgaa gatattgagg cgctggacat cagtgattta caaaaagcct ataaggctgc
    15541 ctaccaagcc caacggatga cactgttttt gattgggggc tcagaaaata cagaaacgct
    15601 tttgcctcct cacctccagc tggaaaagcg cccggattat catgctgaaa gaaaaatcat
    15661 tccgtcatgc cctccagccc tctcacaaaa aatggtactg ggtgatgagg agcggatgga
    15721 agatacatgg accggattac agatcggcgc acttcccggg caaaacgatc tgttgtcgat
    15781 aaagctttat tgggatatcg cggctcgtat tctatttcaa ttagattcac cgttttttca
    15841 agagattcag caaacgtacc tcctggaaat cgatcgcttg tcagccgaga cttatatata
    15901 tgaggatggc ggtttcttga tccttcacag tcaagggatc cattcttcag cttatatcga
    15961 tgtggcttca tactatgtca cacagaagaa agaacaggct gccgcctggc ttcaatacgg
    16021 caaggactct ttgacagacg cgatcattta tgacagcgat tatgtgcgta aatgcttcga
    16081 gtgggcagcc gagtgtgaca ggtgcgattg ctcgtttctt gacatgtacc acaccattca
    16141 agatatggat acgcaggttt tcttgtctct cattgatgca atggcatctt ctaacaaagc
    16201 gatcattcac gtttctcaga aagaggcgat cagacaatga aaaaaaacac tgtctttacc
    16261 cttttattgc tgcttatagg tatggcggct tattccttcg gctcggttca ggccgtttcc
    16321 gaagccgccg cccaatatgt acagatgatc aacaatgatg ctgtgcggct cggactgctg
    16381 gcttgtaccg ctgccctcct gatgctgcct gcttttctct atcttcacta tgtcacccaa
    16441 tccgtgaaaa acatgacagc agcttttcag aaactcacac agtctcatca aagctgctgt
    16501 gactttcagc aacacaactt gtgcagccga tatgcagaag acgtcaaatc gctgcgtgac
    16561 agctataaaa acgtccgcca aacatacgtg atggctgccg tgttgtgcca agtcatcata
    16621 ttcggctgca tgttcgaaat cgttaaagcc gtccctttcc gccttcacac gccccctgcc
    16681 ctttcaatgg gacttgcgat gctactgatc ctgtatttat tgttttgcat gcgaacgtat
    16741 ttgcggcagc ttttccggca cggcagcctg ttcagaaaag tgtttgcggg agcgctggca
    16801 gcagccggga tttggtggat gctcagtttc tctataagtg aacttctgtt tctgattatc
    16861 ctgggtgcca tccagcaaat cggatcattt atttataaac gattctctta tcgcagcacc
    16921 gcttctcttg atctataaaa tagctacatc gcaatcgcag acggacccgc gccaaccggg
    16981 atcaccgtca cggctgtata atcacttgtg cggtacacgg tcacagcatt gtcgttgggc
    17041 tgtgccgcat aaatatactg tttgtccggc gttacggcga ggtcaaaagc gccggggaga
    17101 gacacgtttg caatgatcct ctgtctggcc gtattaacta cgtataagtt attaatgaga
    17161 aacggttcac tatatggctc tagaaaataa gctctagtac tatcgagaga aaatacaatc
    17221 gtcctcagcg tttcaaataa acggctgaag tcccctcccc tgcttaatgg tgacaaacta
    17281 atctccgtta cacctttcgg ccacagctca ccattcaaca cgtacgcaaa gtttccagcg
    17341 taaggagttg caattaaact gggaaattca aatgtatcta tgatactttc taccaactgc
    17401 ccagtattta catcatattt atcaaccgac caactgcttc cattagcggt atagacatac
    17461 tgtccattcg gatcaagagc aaagtctaaa gcgccgggta tcggaatgac atcaatgacc
    17521 gattgagagg ccgtgttaat cacatatata gatccggctg ccatcacgta cgcgaactca
    17581 tctgttggat caaattcaat ctttctcggc cctcctccaa cagtaatggt atttatgatg
    17641 gttaatgttt tattatcaat cactgagaca aggttggtat tcccatggag aacatacgtg
    17701 aatgctttat cgaaagtaac gcctagatta gttggcacag cagaaaacgg gattgttttt
    17761 acaatagtgt ttaaatctgc atcaatgacc gaaaccgtgc tgtctccagt attggcagta
    17821 tacacatacg attgagggtc tggcgatggc ggtaaaacaa gtgtcccggc caccgtaagc
    17881 ggactgccgt agaaaggcgg tacaatgaga agatcttcca ctgttatttg actgaaatca
    17941 ggacagcggc cagactgtgc tgcataataa acaacttgat caatctcttc agtatgaatc
    18001 acagaaacag ccccgtctcc ttgtccatat tgatttcgca caggcgacac actgacaaga
    18061 agcgtaatgg tcccttgtac tctcacggca tatcgaacac cgatatcttc tggttccggc
    18121 ccagtctgga ttaagcaagg ctcactgata caggacaaat tgtctgtact ccatgtaaca
    18181 gccgctgacg cttccgccga atcaaccttg aagccctcag ggatatctat cggcacttga
    18241 aacggcgctt cccggctaat ttcctcatca caaaaacaga aacaattttc ctgtaaagca
    18301 gaaagatcat tctttttcat gatttcacgt ccttttagaa atgcacaaca tatagttgat
    18361 taaatcgcaa tagctcccgg tgaaacccca agagatatga cagtctccac ggagtaatca
    18421 tccgtgttgt aaacagtgat gctctgttct aggacatgag ttgcatacag aaactcgcca
    18481 ttcggggtaa acgcaaagtc tcttgccgac tgtggaacat ttcctataac gcctgctcca
    18541 tttagactga cagaatataa attgccagtg aagccatcat ataaatagac ctctgctcca
    18601 ctcgtaaaca ttcgatattc cccttcatac tccagctctt gggtgctgct gatggtaaac
    18661 gtatttaaat caataaccgt caaataatta aaaaagaatt cttgttctaa tacataggca
    18721 taccgctccg gccaatttgt ttctatggtt gatacgataa gctctcgttc aattgttcct
    18781 gtgacttcac cggtagttag gtccactttt tgcacgatac caaaatttag aacataggcg
    18841 aataacccat tgggatcgat tgcaacatca tacccttcta caggaatcga cctatccaca
    18901 gttaacgtat caattccaat cacataaacc gcagtaccgg tgaaaacata agcaaactca
    18961 tgattaggga taaatctaat caatcgtggc ggctgatcca gcaatatagt tgctgtcact
    19021 gttaatgtgt cataatcgat gacagaaatc acattattgt tgggatgtaa gacaaacaca
    19081 gcgcttttat ccggggtaat ttcaatacct gccggattgt acggaagagc aatcgttgtc
    19141 acaacagagt gagtgtttgt atcaatcaca gaaactgatt gatcatttgg attcgcagta
    19201 aacgcataaa cgggttccgg ctccggtaca agcacaatcg tccccgtcac cgataaagga
    19261 ctgccgtaaa acggcggaac aacaacaagg ttctcaatcg tgatgtcact gatatccggg
    19321 caatcatccg gttcatcgga ataatagacg acttgatcga tctctgcatt gtgaatgacg
    19381 gaaacagccc cgtccccttg tccatattga tttcgcacag gtgagacact gacgagtagc
    19441 gtaacggtgc cctgcaggcg cactgcaaat tgaacaccga cctcatcagg ctcaggcccc
    19501 gttagaatta agcaacggtc actgacacaa gaaaggctgt ctgcattcca cgtcacgttt
    19561 gcaacagctt cagccggatc aacgacaaac ccttcaggta attcaatcgg tgcttgaaac
    19621 atggcttctc ggcttgcttc tccctcacaa aaacataagc actcttcttg ttctgctcct
    19681 gctttttctt taaaggaaag cttgtttttt ctcattcctt cacttccttt tcagacatac
    19741 actgctcacg cagatataac agaatatgga agagtaacgt gtttgcttgt acaaattact
    19801 gagggtaaaa gcttcttttt gaaaatatat ctccaaacat gcggtgtaac gaaagaaaaa
    19861 attgcggttt ttttgcgctt ctcacaagaa tgttgatgat aaaatatgac atatatagaa
    19921 ttatgaaggg agggatttgc aaacgtgaca ggtgccatat cttcttcttc catcggagaa
    19981 aagattaacg aatggtatat gtacatacgc cgattcagca tacccgatgc agaatatttg
    20041 cgacgagaaa tcaagcaaga gctggatcaa atggaagaag atcaagacct tcatttgtac
    20101 tattcactga tggagtttcg gcacaacctg atgcttgagt accttgaacc gttagaaaaa
    20161 atgaggattg aggaacagcc gagactgtct gatctgctgc ttgagattga taaaaaacag
    20221 gctcgtttaa ctggtctgct tgagtactat tttaacttct tcagaggcat gtatgagctg
    20281 gatcgccgtg aatatgtatt agccattcaa ttctttaaaa aagctgagag caagctggtc
    20341 tttgtgaaag ataaaatcga taaagctgaa ttctttttca aaatgtcaga agtctattat
    20401 tatatgaaac aaacttatgt ctccatggac tatgcacgtc aagcattcga aatatacagt
    20461 gaacagacta catatgatat cagaatgatt caatgccagt ccttattcgg agccaacttt
    20521 ttggatttaa aacaatacga aaaagcaatt gctcattttc aaaaagcctt tacacttgca
    20581 aaaacagagc agcagcccca attaatggga agaacacttt ataacatagc actctgcaag
    20641 caaaaccaaa acagttttga atcagcgata gagtatgtaa aaaaatctat tcaagtattt
    20701 gaaggatcta aaatgctccc ttcactgcca caagcttttt tcctaattac acaaatttat
    20761 tttaaattag gtaagattga taacgcctgt gaatatcata aaaaaggaaa agagtattct
    20821 gcagctgcgg gagataccgt gtatctaacg gagtttgaat ttttggaatc tttatacttg
    20881 tctggaccgg atgaggaacg gatagaaaaa tgttttgttt ttcttgaaag taaaatgatg
    20941 tatgcagata ttgaggactt cgcacttgat gttgctaaat attatcatca acaggaaaat
    21001 tacaaaaaag catctcatta ctttttaaag gttgaagaag caagacagca cattcaaggg
    21061 ggggtgaatt tatatgaaat ggaagtataa attattactc gcttgtttag ctgtgagtgc
    21121 tgtatttatc acagtcgaag tatcaaattc atcaacagaa cattttgatg ttgcgcaacg
    21181 cgccatgatc taaaccgccg tccatcggcg gtttttttgt cccctcttta cccaatctcc
    21241 caattcaagc tacgattttt tcaataatct tgaagatagt ggaaatgcac catgtctctg
    21301 gaaagtgtga gaacccactt tacacagtgg aatcgagaaa atgatgtgac ggagttcgaa
    21361 acatccagcg cgacagttga acaggcagct gagacgatcg gcgtaagccc ggctagaatc
    21421 gccaagtccc tgtccttcag agggggagat caggcgattc tgattgtggc agccggcgat
    21481 gccaagatcg acaacaaaaa gtccaggcaa acatttggct ttaaagcaag aatgctctct
    21541 cctaatgagg tactggagca gacaggccat gaaattggag gagtttgccc atttggattg
    21601 gctcatgatc ct
//
