LOCUS       gnlProkkaAOAIJLBN_24   14295 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AOAIJLBN_24.
ACCESSION   gnlProkkaAOAIJLBN_24
VERSION     gnlProkkaAOAIJLBN_24
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 14:09:31
            Original ID  :: gnl|Prokka|AOAIJLBN_24
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 46408
            Orig. end    :: 60703
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14295
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:9295]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9295
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..14295
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14295
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(238..1071)
                     /locus_tag="ctg24_41"
                     /transl_table=11
                     /translation="MAIAYDGINYFPVGVNFMEENAMEVIEAKYGIKGSAIVLKLLCKI
                     YKEGYFIHWDEEQCLIFANKAGREVQAAEVQGIIEILFIKGILDRNSYLANGILTSANI
                     QKIWMEATKRRKRDLKALPYLLVNDLTQQETEAPEGENVTISPGNVVHDVAVNAKNACN
                     SGQSKVKEKKAEENKELPPSAPPKGKEKEWEEVSAPLPIPGYAFNTMTHNYPGLTDTLK
                     RLGITEAGEVNAILRLSDYGRKGTRVWQLIANTCWSDIGAKGRYLIAALNKAKRK"
     CDS             complement(1210..1557)
                     /locus_tag="ctg24_42"
                     /transl_table=11
                     /translation="MKQKKRPASQTEAMKLRWKKRIVFEKGYTEQCAEWMAERLEALTD
                     HLQYGHAAIAYQKQNGDFRLVKATLIYYEAEFHKKYDPTQIEGAVVYWNVDEQRWTTFQ
                     MENFMEWRPIV"
     CDS             2753..3184
                     /locus_tag="ctg24_43"
                     /transl_table=11
                     /translation="MRYEYVFRGERKIRKLVPVVHNLVFVYATRSEVDEMKSTVGASLP
                     IRYIMDRETRQPITIPEVQMRSFIAVAGNYDEQVVYLDPSVVSMKKGDRVRVTGGIFEG
                     VEGEFVRIKGDRRVVVSIQGVMAVATAFIHPSLIELIKN"
     CDS             3243..3728
                     /locus_tag="ctg24_44"
                     /transl_table=11
                     /translation="MLSLQSEIDSLCAVSHELLHLGLDGEPIYSDRFRQLNTDVYHRCE
                     HLFGSHGRTLEEEASLCIALLTGYNATIYNHGDKEDKIQSVLNRSWDLLDTLPASLLKC
                     RLLVACYAEVFDEELAAEAHAIIDGWKDRELTREECEIVEHLKSLEANPYPYSELHE"
     CDS             3725..5008
                     /locus_tag="ctg24_45"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             5001..5720
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.5; E-value:
                     3.8e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_46"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.6e-15, bitscore:
                     48.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTAMIMAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLS
                     CGIERIILGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLL
                     ESDLVFERKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKG
                     ELVGIHKLSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEI
                     DDEADLSYAEEHIIRYC"
     CDS             5668..7041
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 213.9;
                     E-value: 4.6e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_47"
                     /sec_met_domain="CTP_transf_like (E-value: 8.2e-12,
                     bitscore: 37.4, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 6.3e-122, bitscore:
                     398.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 3.1e-64, bitscore:
                     208.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKPTFRMPRSTSSAIVKNKSFPYMNKKIYVGMTADIMHPGLIHI
                     IHEATKYGDVIVGLLTDKAIAEHKRLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNL
                     EKLKPDYIIHGDDWKTGPLREVREQVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIG
                     TTPDVRLKSLRRLIQAKPVVRILEAHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDS
                     TSKGKPDIEAVDLTTRLQDLNNILECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAV
                     IIEDKVGLKKNSLFGTDAIQTQDSIEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPM
                     SDALERAYAYVQAGADGIMIHSKDKSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHES
                     ELHEWGANVVIYANHLLRAAYPAMMNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             7053..8189
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_48"
                     /sec_met_domain="TPP_enzyme_N (E-value: 8.7e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.9e-20, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             8186..9295
                     /NRPS_PKS="Domain: Aminotran_5 (30-298). E-value: 6.3e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg24_49_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_49"
                     /sec_met_domain="Aminotran_5 (E-value: 4.6e-31, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAQYLLFIR"
     aSDomain        8276..9079
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg24_49_Aminotran_5.1"
                     /evalue="6.30E-34"
                     /label="ctg24_49_Aminotran_5.1"
                     /locus_tag="ctg24_49"
                     /protein_end="298"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIKREWQS"
     CDS             9326..10690
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_50"
                     /sec_met_domain="Polysacc_synt (E-value: 1e-14, bitscore:
                     46.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVVFNSNKFFCWINQALITCVSRIICVIETLVPSKFSDKIRILR
                     SHEVVFYNVIGLTFFNSLGGLLTILTQVKLANVMGASHYGVYSYCLAIGEVGAMVVRYG
                     RHKTMVRDLIQYPVRNLQLISSTFIIGVINFLIFLGLVLVFHQDIDIQISVGTVLLICG
                     ACLISLDFQPVYESLNAMSWHSMYNLFQKLIFVIILWGIMLSPFTLSLNVLGIVFFFSW
                     ILVIVWQYKEITSFFHLKIISTCEWSKLFKLYRENFVVAFSCLFGIAFGPIIRIVLNNY
                     CNSREVGVFSAGLQILLIAQFILNQIGRIGNPMMAIIGKDNCSMKQRRLFVYRYLFIML
                     SSTLPFFIPFFFFPSLVVNMFFTEEYADLVIMLPILAVYLIALSVGVVYTQFLISMRKD
                     RLYFIIYVLGATLTILCAFLLIPILGILGATLSLCVPHALTCLCYWWFSANLLRK"
     CDS             10693..11595
                     /gene_functions="resistance (resist) AAC3 (Score: 59.5;
                     E-value: 1.6e-18)"
                     /gene_kind="resistance"
                     /locus_tag="ctg24_51"
                     /transl_table=11
                     /translation="MFVEKIRIRILLVRWIKTIFHISDLNLFLRDVRLYSSKLVYCKKF
                     TVVDLVNLMCEMGMKPGSTIVIHCAMKQFYNFSGTAEELIDAIIEKLGPEGTLCMPSYP
                     FDKKNENILFDVIKSPTAAGYLAETFRKRKGVKRSLNKLHSVCAFGKYADYLINEHHLS
                     KTCFDEKSPYYKLAKLNGLSFSLGLPKYYIGTIEHVCESLLCNELGFFRDCFLKEVNFR
                     YKDENQLEIYHKMWTCDRLYLRAHNSKLIDTYFDKEKFSRKRISNLRVSMFDVGYTVDR
                     LVDLAMQGKTLYSYPKFYK"
     CDS             11598..12836
                     /locus_tag="ctg24_52"
                     /transl_table=11
                     /translation="MPQIIFILGILIYRFFLDNVYIQTIAPFYAYQGLDYVGTNIDYWI
                     SWGVLIAFSLLMSLLLKYKEFFLSNILILLFLIRFVPFTSLLACKSLDNRLLLMELIYW
                     GAIFLFSLILKRPCLHFSFPKRYKLSTLRFSVVDIVLVFSVLIVLFVSGCYAHFRLNFS
                     LMNVYDLREEARDFSMPVLLKYLWSATGNVLPVLFVYYLIIKRRIVCCFIAFVILLNFS
                     VDGLKANIFKLFLCLLLHLVYKQNLIKMFPWLFALLCFFSLAEYYVFSTPLLSEFVVRR
                     VLYIPALLDSYYFDYISKYGPVFYQRGDVHIDFIIGEEYFGKASMRANNGLFTDAYMNL
                     GEIGCLVYPFVYVAFFKFCESSFEGVNVELVMFVIIIMVITLNSSEFTTSLLTHGLFAL
                     CLLLYFLPRKRYD"
     CDS             12906..13610
                     /locus_tag="ctg24_53"
                     /transl_table=11
                     /translation="MNIENSRIYFFLRNSVLYGMLQPILRFYYRRCRKRAMKLYACELL
                     ENMKQILDKNNILFWLDFGTLLGAYRDKDFISYDCDIDIAILYEDAERVRNLLKNSDFC
                     LTHEYRVGKAGEVAQLSYKYKSLSIDICFYHKKNESMYCYLCSILPGVSIVNNRRCVVA
                     VAKCVVPCEKFADINFHKLIYHAPFPTEEYLAAHYGPNFMIPDSKFDYTKDAPNITNYA
                     IEELAGECIYND"
ORIGIN
        1 ttgtctgcaa ataacaagtc ttttgcattt aaagaatttg ctatttgcag acgaaaaacg
       61 aactttaacg taacgttaaa ataaagcttc tgcagattga aatattgtgc tctgaagtgg
      121 ctgtagatca tttgtttaaa tgtatgtccc gttttccatt cccgacagag aaccttccgt
      181 atggaaaccg gtatacttgc ttttttatca actgcaaact gtactttcct atccggatta
      241 ttttcttttt gccttattca gtgctgctat cagatacctt ccttttgccc ctatgtcact
      301 ccagcaagta ttggcaatca gttgccatac ccgtgttcct ttccttccat aatccgatag
      361 cctgagtatg gcattcacct ctcctgcttc ggtaatcccc agtcttttga gtgtatctgt
      421 cagtcccgga taattgtgtg tcattgtgtt gaaggcgtat ccgggtatcg ggaggggagc
      481 agaaacctcc tcccattctt tctccttccc cttgggggga gctgaggggg gtaattcttt
      541 attttcctct gctttctttt cttttacttt actttgtccg gaattgcatg cattttttgc
      601 gttaacggct acatcatgta ctacatttcc cggactaatg gttacatttt caccttccgg
      661 cgcttctgtt tcctgctgag tcaagtcgtt caccagcaga tagggcaatg ctttcagatc
      721 cctttttctt cgctttgttg cctccatcca tatcttctgt atgtttgccg aagtcagtat
      781 tccgtttgcc agataactgt ttctgtccaa tatccctttg atgaagagga tctcaatgat
      841 cccctgtacc tcagcggcct gcacctctct tcccgccttg ttggcaaaga tcaggcactg
      901 ttcttcatcc caatggatga agtatccctc cttgtatatt ttgcacagta gtttcagtac
      961 gattgccgaa ccctttattc cgtattttgc ttctatcact tccattgcgt tctcttccat
     1021 gaagtttacg cccaccggga aatagttgat cccgtcatat gctattgcca ttgtttttta
     1081 gattagtcgt ttgtactttc aataatacat tcaccataaa ttaccccgga ttcccaaaga
     1141 tgtcttcact tgatttctca aaataaaaat aattcatcgg tgaaaatccg tgtaatctgt
     1201 ggtggcgccc tatacgatcg gtctccactc catgaagttc tccatctgga atgtcgtcca
     1261 tcgctgttca tccacattcc agtagactac tgcgccttct atttgtgtgg gatcatactt
     1321 tttgtggaat tccgcttcat agtagatcag tgtcgctttt accaacctga agtctccgtt
     1381 ctgcttctga taagcgatgg ctgcgtgccc gtattgcagg tggtcggtca atgcttccag
     1441 gcgttccgcc atccattccg cacactgttc ggtatatcct ttttcaaaga caatccgttt
     1501 tttccatctc agtttcatgg cttcagtttg tgatgccggt cttttcttct gtttcatacg
     1561 tatatgattt aaagggttaa tagataaatt atcgccccaa agataggtca gatcgaatgt
     1621 attccggttt gataaaattc attgtacgta tttcagcgct ttccttcttg gttctttttc
     1681 tttctttcca tcttattcca gatctcgttg acgtaagttc tgattgtgct gaaaactaat
     1741 ggtttgaata ctccatttct tatttttcca aaaagttttt tttcctctat gtagcgtgcc
     1801 aacgaatctt tacatgtctt gatattttgt tcttttgcgt ccaatatgta ggattctatc
     1861 agcgctttta taactccttc attgttggag ataattcccg gtatctgcgt tcctgctttt
     1921 ctgcctcttg tttctttaat agattctgtg ataggaggtt gtgttttagt gttagcgttt
     1981 ttttacactt ttgttcactg tctgtaataa ttcattttct ttgttcatga tttttttatt
     2041 taatcaataa ctaaatgttg ttaatatgtt gcaaaggtag agagtaatct ttcagtgggc
     2101 aaatgaatgt ggaattaaag tgggaatcaa agggaaaatg aaaccttttc tcttcttaat
     2161 tgtctgacat taaatgaaat aattcttaaa aaagtgagtg tttcaataaa cgatcgttta
     2221 attgaacgca aagatagagg gtattttcat aactgcaaaa tgtttaataa aaaaaatgtt
     2281 ttccttcatg gcttgatcta tttaattatt tgataatcaa atgtctataa actaacaaaa
     2341 aacgctttaa tatctgtctg cttttatatg tattttaatt gtctggatct ttaaaaaagt
     2401 gtgtttcaaa agacgatcgt cttttgaaac actttcgctt cataatagac tcgtttacag
     2461 attgtaagat cagtaaggcc ctgttttttc aaaacttcgt tttctgttct tctttttcaa
     2521 actgtctctc ctgcgatagg ggagtacctg atgaaatgat atacgctgca aggcaaacaa
     2581 cagaattagc aaacttgacc ggaaggtgtt tcactacccc ggtgtccccc aattatatcc
     2641 ttttgtgaac aatagcatta ataaatcctg gtacgccctt cgtatcacct atagccgtga
     2701 gcttgccttt aaggaatacc tggactcccg cggagtgagg aattttcttc ccatgcgcta
     2761 tgaatacgta ttccgtggtg agcgtaagat ccgtaaattg gttcctgttg ttcacaactt
     2821 ggtttttgtt tatgccactc gcagtgaggt tgacgaaatg aaatccactg tcggggcttc
     2881 tcttcctatt cgttatatca tggaccgtga gacccgtcag cctattacca ttcctgaagt
     2941 ccaaatgcgt agttttatcg ccgttgccgg taattacgat gaacaggttg tttatctgga
     3001 tccttcagtc gtttccatga aaaagggaga ccgtgtccgt gtcaccggtg gcatcttcga
     3061 gggagttgag ggtgagtttg tccgtatcaa aggtgaccgc cgtgtggtgg tttccatcca
     3121 gggggttatg gcagttgcca cggccttcat tcatccctct ttaatcgaat taataaagaa
     3181 ttaaaaactc tgtgaactct gtgccctctg tggtgcatat tccaatacgt aaataaatca
     3241 ccatgttgtc tttgcaatca gaaatcgatt ctttgtgcgc cgtttcgcac gaacttctcc
     3301 atttaggtct ggatggcgaa cccatctact ccgaccgttt ccgtcagttg aatacggatg
     3361 tgtatcatcg ttgtgagcat cttttcggtt cacatggacg taccctcgaa gaggaagctt
     3421 ctctttgtat cgctttgttg accggctata atgctaccat ttataatcac ggtgataagg
     3481 aagataaaat ccagtcggtc ctcaatcgta gttgggatct cttggataca cttcccgctt
     3541 cgcttttgaa atgccgtttg ttggtagctt gttacgccga ggtctttgac gaagagctgg
     3601 cggcggaggc acatgcaata atagacggtt ggaaggatcg ggaattgacg agggaagagt
     3661 gtgagattgt ggagcattta aagagcttgg aagctaatcc atatccgtac agcgaactac
     3721 acgaatgatt cgttcctttc tttcccgttc tcccctttac gttttggctc tctatgccag
     3781 cgttttgatt tttctggttt atacttgtgc ctatgcctac cgtaagccat ttaccgcagc
     3841 catttatgaa ggtgagattc tttggggatt cgatgtcaaa atcctgtatg tcctttctga
     3901 gattatcggc tacgcccttt ccaagttcat cggtgttcgt attctgcctt cgatgaaagc
     3961 gggtcaccgc atctattata taatagggct gcttactttt tccgaagttg ctttgttggg
     4021 ttttgcactt cttccggttc ctttgaaggt gtgttctatt tttctgagcg gtcttcccct
     4081 gggtatgatc tggggtgtca tttttagcta tatcgaaggg cgtcgtatca gtgaaatatt
     4141 gaatgtcggg ctgagcgttg ctttgatagt ctcttccggt ttggtgaaaa ccttgggaca
     4201 attcgtgatg gataatttgc atgtgtcgga atattggatg ccttttacca ccggtttgtt
     4261 ggtataccct gttatgttgc tttgcagctg gcttctcaat cagattccgg ctcccaatga
     4321 gcaagatatc atacagcgta ccaaacgtgc tccgatggat ggtaaagaca ggcgtaaatt
     4381 tttgaggcaa ttcttctggg gaatctgcat gctggttgtt ttttacggtg ccctgaccgt
     4441 gttccgtgag cttcgtgact ctttcgctgc cgatatttgg aaggagctcc atattgaagg
     4501 tgcaatgatc tttactcaga cagaggttcc cattgccgtt tttgtccttg tactgatgtt
     4561 cctgattgtg tttgtccgta ataaccgttt ggctcttaat attatttatt gcattgccgt
     4621 tacaggcggt tccttaatgg ttttttccac attgctttat gtgtacggtt ttctttctcc
     4681 tatttggtgg atgattcttt ccggtcttgg tctgtatatg gggtatattc ctttcactta
     4741 cctgatagaa cgcctgattg cttcccttag ggtggttagt acggctgttt ttattattta
     4801 tttggccgat tctttcggct atctgggcac tacgggtgtg tttatggtca agaacttcgt
     4861 ttctgctgac atttcctgga ctgtcatgct aatgcgtact gccctttttt caggatttgt
     4921 ttctgtcctg tcgatttttg cgatttactg ttatttcaag caacaattga attcacttat
     4981 attaattccc tctgaaattc atgattaaaa cagcaatgat catggctgcc ggtcttggta
     5041 cccgcttcgg gcattatacc gagcttgtgc ccaaaggttt tgtggaggtt ggtggaaaac
     5101 ctatgattat ccgctctatc gaaacccttc tttcctgcgg tatcgaacgt atcatcctcg
     5161 gtacgggtta taaaaaagag gcttatgaag cccttcaggc ggatttcccc cagatagaga
     5221 cctgtttcag tccccgctat gccgatacta acagtatgta cactctgtac aatacgcgtg
     5281 acgtgatagg cgatgacagt ttcctgctgc ttgaatcgga ccttgttttt gaacgcaagg
     5341 ccatcctctc gctactggat gacgaattcc cggatgtgat gcttgtctct tctctgacca
     5401 agttccagga tcagtattat gtggaatatg accgcaatca catccttact tcctgttcgg
     5461 tagacaagaa cgcccttgag gcaaaaggcg agctggtcgg tatccataaa ctttccaata
     5521 ctttctaccg ccggatgtgc gccgattatg cgaccatcct ggagtcccag cctaaactgg
     5581 gttacgagta cgaactgctc cgcatgtccc gttccgtttc ccctgtccgt gtgctcaggg
     5641 tggagggtct taaatggtat gaaatcgatg atgaagccga cctttcgtat gccgaggagc
     5701 acatcatccg ctattgttaa aaacaaatct tttccatata tgaacaagaa aatctatgtc
     5761 ggtatgaccg cggatatcat gcatccgggg ctgatccata ttattcatga agctactaaa
     5821 tacggtgatg tcatcgtcgg tctgctgacg gacaaggcca tcgccgaaca caaacgcctc
     5881 ccttacctta cctatgatca gcgtaaggag gttgttgaga atatcaaggg ggtttttgag
     5941 gttgttcccc aggaggactg gagctatgtt ccgaatctgg aaaaactcaa gcctgactat
     6001 atcatccacg gcgacgactg gaaaacgggc ccgttgcgcg aggtgcgcga acaggttttt
     6061 gaggtgatga acgcccaggg gggcaaggta atcgagatcc cttatacccg gggcatcaac
     6121 tcctcctcgc tcgacaagga tatcaaggcg atcgggacta cccctgacgt acgtcttaag
     6181 tccctccgcc gcctgatcca ggccaagcct gtggtccgta tcctggaggc tcacgacggt
     6241 ctttgcggtc tgattattga gaatcttgaa gtccagaagg gtgataagcg cgaggtcttt
     6301 gacggcatgt ggtccagcag cctgaccgac tccacgagta agggtaaacc ggatattgaa
     6361 gcggtcgacc ttaccacccg tttacaggac ctgaacaata tccttgaatg caccaccaag
     6421 cctattattt ttgatggaga cacgggtggc aagatcgaac actttgtctt tactgtgcgc
     6481 actctggaac gtcacggcat ttctgcggta atcattgaag ataaagtcgg tctgaagaag
     6541 aattcccttt ttggtactga cgctatccag actcaggata gtatcgaggg tttctgcgat
     6601 aagatcagag cagggaagaa tgcccaggtc accggtgact ttatgatcat tgcgcgtatc
     6661 gaaagcctta ttgccggcaa acccatgagt gacgccctcg aacgtgctta tgcctatgta
     6721 caggcgggtg cggacggcat catgatccac agcaaggata agtcgggtga ggatatccgt
     6781 gagttctgcc ggactttccg caaagaatac gcccatgttc ccattgtcgt tgttccgacg
     6841 acttatgacc atgtgcacga atccgaactt cacgaatggg gtgccaacgt agtcatttac
     6901 gccaaccacc ttctccgtgc cgcttacccg gccatgatga acgtggccag gaccatcctt
     6961 gaaaacgagc gcgccgagga ggtccgtccg ctttgtatgc ctatcaagga aattctggaa
     7021 ttgattccgg gcactaaata aatcagacgg ttatggtaag tgtagaaaag atatacgata
     7081 cgttccttca tcacggtgtt gacttcttta cgggtgttcc cgattccctt ttgaagaata
     7141 tttgcgccta tatcacggat catgctccgc gtggtaagca tatcatcgcc gccaatgaag
     7201 gttccgcggt gggcattgcc tgcggttatt atatggcttc tggcaacgtt cctttggttt
     7261 atatgcagaa ctccggtctg ggaaatacgg tgaatcccct cttgtccctt gcggacgaga
     7321 aagtgtacag ccttcctctt cttttgctgg tcggctggcg cggtgagccc ggcacaaaag
     7381 acgaacccca gcataagaag cagggcgagg ttacccttga tcttctgaaa gccatgaaaa
     7441 ttccttttat aattctggat acggatgaag acgaggccct ggcgcagatc catgacgcgg
     7501 ttgtctcggc gaagagccgg tcgattcccc atgcgattgt catccgtaaa gatacgtttg
     7561 gaaaatataa attgcgtcag gaagccttga atgactatcc tctgtcccgc gaggaggcgc
     7621 taatgcaggt tgtcgaccac ctcggggaca atgacattgt ggtttccacc acgggcaagc
     7681 tctcccgtga gcttttcgag taccgtgaat cgaaagggca ggggcacgca agggatttcc
     7741 taactgtggg ttccatgggt cacagttctt ccattgccct ggggattgcc cttgagaagc
     7801 ctgaccgccg tgtctactgt cttgacggtg acggtgcctt tatcatgcac atgggtgctg
     7861 tcagcaatat cggcgatctt tctcccaaga attacaggca cgtccttttc aacaacggtg
     7921 cgcatgaatc tgtcggcggt caacccacgc tcggtttccg tctggatatc gcctcgatag
     7981 cgaaaggttg cggttatgcg catgtactga ctgcctccga caaggaaggg ctttcgtgtg
     8041 cgcttgagaa gctgtccggc ctgtccggcc cggttcttct tgaaattaag gtccggatcg
     8101 attcacgtga tgatctgggt cgccctacga ctactccggt agagaataaa gagcatttta
     8161 tggcattttt aaaagatacg cattcatgaa tatcgaaaga aagatccttt tgaatccggg
     8221 tcccgccacc acgacggata cggtgaagct ggcgcaggtt gttcccgata tctgtccgcg
     8281 tgagaaagag tttgcgggta tgatgaaaca gttacgtgac gacctggtcc gcgttgcgca
     8341 tggagacctc tccaaacata cggccgtcct gttttgcggc tcgggtacga tcaatatcga
     8401 tatctgcctg aactctcttc ttcctgcgga taagaaagtt ctggttgtca ataacggtgc
     8461 ctacagcacc cgtgcggtgg aagtctgcga atattacggt cttccccata tcgatttgaa
     8521 gttttccgtt tacgaacttc ccgacctgtc ggtaatcgaa aagacgcttt ccgacaatcc
     8581 ggacatcgct ttggtctata ccacgcacca tgaaacgggt acgggtatct tgaaccccat
     8641 ccgtgagatc ggaaaaatag cccattcgca cggtgccgtt tttgttgtcg acaccacttc
     8701 ttccctgggt atgattcctt ttgatatcgg gaaggataat gttgactttt gtatggcttc
     8761 ggctcagaaa ggccttcagg ccatgacggg tctttccttt atcataggtg atgaatccct
     8821 gatacgtgct tcaagggatt atccgaaacg ctcctactat tgtaacctct atttacaata
     8881 cgattacttt gagaagacgg gtgagatgca ttttactcct cctgttcaaa ccgtttacgc
     8941 tgcccgtcag gctcttgatg aatattttgc agtaggtgaa gaggctaaat tcgcccgtca
     9001 caagagggtc tttgaagcca tccataaagg tttgcaagag cttggtcttc agtatgcgat
     9061 caaacgtgaa tggcagtcgg gtcttgttgt ttctgtattg tatcctgatg atcccctctg
     9121 ggattttgat aaggttcatg attactgcta tgaacgtggc tttacgatct acccgggtaa
     9181 gatttccaca acgaatacat tccggctttg tgcgttggga gagattgatg tggaggatat
     9241 tgagaggttc tttgaggtga tgagggaggc acaatatctc ctatttataa gataggtcgt
     9301 tgattggaag aaatgtttct ttagaatgga tgttgtgttt aattcaaata aatttttttg
     9361 ttggataaat caagctttaa ttacttgcgt tagtaggata atttgtgtca ttgaaacttt
     9421 ggttccttct aaatttagtg ataaaataag gattttaaga agtcatgagg ttgtgtttta
     9481 taatgtaata ggattgacat tctttaattc gttgggagga ttattgacta ttttgacaca
     9541 agtaaagcta gccaatgtaa tgggagcttc tcattatggg gtatattcat attgtttagc
     9601 tattggagaa gttggtgcta tggtagttcg ctatgggcga cataaaacaa tggtacgaga
     9661 tcttatacaa tatccggtta gaaatttaca acttatttct tccacattta ttattggggt
     9721 aattaatttt ttgatttttt tagggctagt tcttgttttt catcaagata tagatattca
     9781 aatttctgta ggaacagtgt tgcttatatg cggtgcttgt ttgatctcat tggattttca
     9841 acctgtatat gagtctttaa acgcaatgag ttggcattct atgtataatt tgtttcagaa
     9901 attgatattt gttattatct tgtggggaat aatgctgtct ccatttactt tatctttgaa
     9961 tgtattagga atagtattct tcttttcttg gatactagta attgtatggc aatataaaga
    10021 aataacttcg ttttttcatt tgaaaatcat ttctacatgt gaatggagta aattatttaa
    10081 gttgtatcgt gaaaattttg tagttgcatt tagttgtctt tttggaatag cttttggacc
    10141 aattattcgt attgttttaa ataattattg taattcacgg gaagtgggag ttttctctgc
    10201 aggtttacaa attttattga ttgctcagtt tatattaaat caaattggac gtattggtaa
    10261 cccaatgatg gcaattattg gaaaagataa ttgttctatg aagcaacgga gactttttgt
    10321 atatcgttat ttgtttataa tgctttcaag tactttgcct ttttttatac catttttctt
    10381 ttttccttct ttagttgtta atatgttttt tactgaagaa tatgctgact tagttataat
    10441 gttacctatt ttagctgttt atttgatagc attgtctgta ggagttgttt atactcaatt
    10501 tttgatttcg atgagaaagg atcgacttta ttttattata tatgttttag gagctacttt
    10561 gactattttg tgcgcttttc ttcttattcc tatattgggg atattggggg ctactttatc
    10621 tttatgtgta cctcatgctt taacttgttt atgttattgg tggttttctg ctaacttgtt
    10681 aagaaagtag ttatgtttgt tgaaaaaata agaattcgta tcttattggt acgttggatt
    10741 aagacaatat ttcatatatc ggatttgaat ctttttctgc gtgatgttag attatatagt
    10801 tctaaacttg tttattgtaa aaaatttaca gttgtggatt tagtgaattt aatgtgtgaa
    10861 atgggaatga agccaggatc tacaatcgtt attcattgtg ctatgaagca gttttataat
    10921 ttctcaggta ctgcagagga gttaattgat gcgattattg aaaaattagg accagaaggt
    10981 acattatgta tgccttctta tccatttgat aagaagaatg aaaatatatt atttgatgtt
    11041 ataaagagtc ctacagctgc tggatattta gcagaaactt ttagaaaacg aaaaggtgta
    11101 aaacgaagtt tgaacaaatt acactcagtg tgtgcatttg gtaaatatgc tgattatctt
    11161 attaatgaac atcatttatc taagacgtgt tttgatgaaa aatctcctta ttacaaactt
    11221 gctaaactga atggcctttc ttttagtttg ggtttgccta aatactatat tggaaccata
    11281 gaacatgttt gtgagagttt gttatgtaat gaactaggct tttttcgaga ttgctttttg
    11341 aaagaagtta attttagata taaggatgaa aatcaattag aaatttatca taaaatgtgg
    11401 acgtgtgatc gtttatatct tcgagcacat aatagtaaac taattgatac ttattttgat
    11461 aaagaaaaat ttagtcggaa gcgaatttca aatttgagag ttagtatgtt tgatgttggt
    11521 tatactgttg acaggcttgt tgatttagct atgcaaggga agactcttta ttcttatcca
    11581 aaattttata aataagaatg cctcagataa tttttatatt aggtattttg atctatcgtt
    11641 tttttctaga taatgtctat atacaaacaa tagcaccttt ctatgcttat cagggattag
    11701 attatgttgg cacaaatata gactattgga tttcttgggg agtgttaatt gccttttcat
    11761 tattgatgtc attgcttttg aaatataaag aatttttttt atctaatata ctgattcttt
    11821 tatttttgat tcgttttgtt ccatttactt cacttttagc atgtaagtca ttagataatc
    11881 gtttgttatt gatggaattg atatactggg gggctatttt tttgttttcg cttattttga
    11941 aacggccttg tttacatttt tctttcccta aaagatataa actatctaca ctaagatttt
    12001 ccgtagttga tattgtactt gttttttctg ttttaattgt tttatttgtt tctggttgct
    12061 atgcccattt tagattgaac tttagtttga tgaatgtata tgatttaaga gaggaggcac
    12121 gtgattttag tatgccagtt ctcttaaagt atttgtggtc tgctacagga aatgtattac
    12181 ctgttctttt tgtttattat ttgattataa aaagaagaat agtatgttgt tttatagctt
    12241 ttgttatctt attaaatttt tcagtcgatg gattgaaagc taatatcttt aaattgtttt
    12301 tatgtttgct tttacattta gtgtataaac agaatttaat aaaaatgttt ccttggcttt
    12361 ttgctttact ttgtttcttc tctttagctg aatattatgt atttagtact cctctactat
    12421 ctgaatttgt agttcgtagg gtcttatata tacctgcttt gcttgattcg tattattttg
    12481 actatatatc gaaatatggt cctgtttttt atcaacgtgg agatgtacac atcgatttta
    12541 taattggaga agaatatttt ggtaaagcat caatgagggc taataatggt ctttttactg
    12601 atgcttatat gaatcttggt gagataggat gtctcgtcta tccatttgtc tatgttgctt
    12661 tttttaaatt ttgtgaatcg tcttttgaag gcgtaaatgt agagttagtc atgtttgtca
    12721 ttattataat ggttataact ctcaatagtt ctgaatttac gacttcttta ttaacgcatg
    12781 gtttatttgc tctttgttta ttactttatt tcttaccaag gaaaagatat gactaaatgg
    12841 tcgttttgta ataaattgta attgctacta tctgtgcaac attagttaga taaaatataa
    12901 ttgttatgaa tattgaaaat agtagaattt atttttttct tcgaaattcc gtgctttatg
    12961 gaatgcttca gcctattttg cgcttctatt atagaaggtg tagaaaacgt gcaatgaaat
    13021 tatatgcttg tgagttatta gaaaacatga agcaaatatt ggataaaaac aatattttgt
    13081 tttggcttga ttttggaact cttttaggtg catatcgtga taaagacttt atttcatatg
    13141 attgtgatat tgatattgca attttgtatg aagatgcaga acgtgtaagg aatttattga
    13201 aaaattctga tttctgttta actcatgaat atcgtgttgg aaaagcaggt gaagtggctc
    13261 agttaagtta taaatataaa tctttgtcga ttgatatctg tttttatcat aagaagaatg
    13321 aatctatgta ttgttattta tgctctattc tgccaggtgt ttcaatcgtg aacaatagaa
    13381 gatgtgttgt agcagttgct aaatgtgttg ttccatgtga gaaatttgca gatataaact
    13441 ttcataagtt aatatatcat gctccatttc caacggaaga gtatttggct gctcattatg
    13501 gacccaattt tatgatacct gactctaaat ttgattacac aaaggatgct ccaaacataa
    13561 ctaattatgc tatagaagaa ttagctggtg aatgtatcta taacgactaa aatatagatg
    13621 aagattttac atatatgtaa tgcttatcag acaaattctt tatatcaaga gttgtttgat
    13681 agaattcaaa aagataacat tgatcaagtt gttgttgctc caggatatta taaatctggt
    13741 agtgaatgtg ttaatggagt ccaagtactg tattatttta gaaaaactgg tggttttcaa
    13801 cgcttgttct ggaagcataa agtaaatcgt ataacaaaat atgctttgtc aaatgtaaca
    13861 atatcgactg tggatattat tcatgcgcat actcttttta gtgatggggc tgtggcttat
    13921 caattgtgga aaagacattc gataccgtat gttgttgccg tcagaaatac agatataaat
    13981 ttctatttta agtacttttt attttatcgt tctttaggat ataatatatt aaagcatgca
    14041 agtaaggtgt ttttgatttc agattctaat aaaaagaaat tttataatat attacctact
    14101 ggaatacgga aaaatataga acataaaaca gaagtcttgc cgaatggcat aaatgattat
    14161 tggttgttgc atcggaatta taaaacatcc cataataaaa aaaaatgcag tgaaattaat
    14221 ttggtatatg taggagattt tgttaaaaat aaaaatattc atatggtagt aaaggctgtt
    14281 gaatatttaa ataaa
//
