LOCUS       c00004_gnlPro..        24639 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FPKOFMHD_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 17:35:24
            Original ID  :: gnl|Prokka|FPKOFMHD_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 181299
            Orig. end    :: 205938
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24639
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[191299:195938]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14639
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24639
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24639
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             240..1754
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 268.7; E-value:
                     2.3e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_145"
                     /sec_met_domain="AMP-binding (E-value: 7.8e-82, bitscore:
                     268.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSSQKDIINDILSAMQCYPENEAFIIDDKHYTYAQLGEITASI
                     THSLSEIKDEKIGIVAENRIETYAAILAVLAGGKTYVILHPAYPEERNLKIAALAGLRT
                     LLCTSDTDRSAFGTGHFRIIDTDRLPGKTLSEQQSHSSDEERNAYIIFTSGSTGEPKGV
                     PITRANLNAFYRAYSSLDWNLDEHDRMLQMFELTFDVSVVSLLYPLTLGAAVYTVGHQD
                     VKHFKVFELLEKYQLTFATVTPSLLQLLSPYFDEINLPSLKYLGVSAEASQTELLERFR
                     KSAPNATFINLYGPTEATIYCTCYRIPASDKCKHYNGMVAIGKPFPGIRAIIADEEGNE
                     LPQGETGELWVSGRQVMKGYLDDPEKSALVLIHRPDGQIYYRTGDLCILDGDGDIIYCG
                     RKDYQVKIQGFRIELSEIEYTAQSFFKTPCSVAAVPLLCDGICNELHLAVETTECTQSA
                     LIEYLKEKLPKYMLPKQIHCISQFPVTNSNKTDRKKIAELIKEKKL"
     CDS             1769..2011
                     /locus_tag="ctg4_146"
                     /transl_table=11
                     /translation="MNREEVLKQLQSIFRNILKKDNVCIDESSTSKDVDGWDSLTHMQI
                     IAQIEKHFGVRFNFREVIKFKNVGDLCSALLTKME"
     CDS             2015..3397
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MBOAT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_147"
                     /sec_met_domain="MBOAT (E-value: 1.8e-21, bitscore: 70.5,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFLSFSFLALFTLCFFLYYAVKGRARNLILLVTSCIFIGWYYLP
                     FLLTAVVVALFTFFWAQWMESRAKAGKKTKPVYIAGIIALIGGWLLLHGTVIDDIIFPL
                     GMSFYTFQAISYLTDVYWQEQRSERNWVDFLIYMLFFMKFLSGPIERGGDLLPQLKDPR
                     PFIYSNAVTGLKYILLGLIKKLLIANQISPQTDVMFHSIHDLSGVQLLMTCLLYPIELY
                     ADFSGYTDIAIGGAYMFGIKLSPNFNRPFAARSTADFWRRWHMSLSFWVRDYLYVPLTA
                     GTRNWGQWGIYFSLLITFLALGLWHGAGLTFAIYGLIQGVLICWEMKTAAFRNNLPQYI
                     GKYAADSLLIVRTYLLFALSLIFFRVQSLSDAWYFLRNISFEVHSSWKEMNIGIRDHNC
                     IVAGSALLLVLIYEYYASKYNLMETLERQPAWLRWSVYYLLVFALLMLGKFDTETFIYL
                     QF"
     CDS             3416..4456
                     /locus_tag="ctg4_148"
                     /transl_table=11
                     /translation="MLHHSSRISPKTRFCLKLLLLILPLIPIVVVYFMFDPYRVLHPYK
                     RFDDSPMLLNEAHVGWQNYLQNRDSIAYNSFILGNSCTMAFLTGEWEKYLDKNDHAVRF
                     YDNGESLGGVRQKLQLLDSVGAPLKNVLIVLDKKSLDKNAPLSGNNHLFSAEAAGISQL
                     GFQLRFLQEFLYPDRMIPYIDYLIRHKYAPYMKGVINPGDPVREPYTNNFINPREKEIA
                     QDGEIYWSRHEKEFKKRTNAGMEELPVIFASQIQVLRSIKKICDKHHTNLKFIIGPDYY
                     QKKTSREDIKILKAILGDSAVWDFTGINEYTADIHHYYEPGHYRPLLGARLLKAIYQDQ
                     DTCHRQ"
     CDS             4561..4767
                     /locus_tag="ctg4_149"
                     /transl_table=11
                     /translation="MKKILLLLSVCISFSSCCTLFSSSKQDITFTGMNGTKIYEASTKQ
                     KIAEIKEDNSVTVQIKKKGKTNN"
     CDS             complement(5145..5774)
                     /locus_tag="ctg4_150"
                     /transl_table=11
                     /translation="MLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGVD
                     YVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKALG
                     KPVGRQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVDH
                     YQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPIQKLYRELKQL"
     CDS             complement(5758..6279)
                     /locus_tag="ctg4_151"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALAFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVSDLYFGSAVKIHDYRGFRDKYGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             complement(6300..7091)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_152"
                     /sec_met_domain="F420_oxidored (E-value: 3.3e-13, bitscore:
                     43.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVSHYGVFYPMQTFSKQREVDFKEIPFFIEASSAEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYALAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             complement(7088..7420)
                     /locus_tag="ctg4_153"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVMGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFIKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             complement(7423..7920)
                     /locus_tag="ctg4_154"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLS
                     ELSHCKEQASAFIADAALAIVVTADPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             complement(8126..8668)
                     /locus_tag="ctg4_155"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMIAHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             8786..9769
                     /locus_tag="ctg4_156"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRMFPPAFIKRCEIYGTGEYLIAEADKERIFGEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENAEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALQDAHQNGFRHMEF
                     MDAGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_157"
                     /sec_met_domain="Glyoxalase_4 (E-value: 4.4e-23, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10531..12084
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_158"
                     /sec_met_domain="CT_Btheta (E-value: 4.2e-290, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12105..13019
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_159"
                     /sec_met_domain="OAD_gamma (E-value: 2.6e-15, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             13045..13476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_160"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.6e-21, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             13479..14639
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_161"
                     /sec_met_domain="OAD_beta (E-value: 8.1e-153, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14787..16118
                     /locus_tag="ctg4_162"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALKELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             16135..17427
                     /locus_tag="ctg4_163"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVVLQAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKSLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQIRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIEDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPTPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             17975..19825
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_164"
                     /sec_met_domain="Alpha-amylase (E-value: 1.1e-62, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVY
                     GEGIGQASVSVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWADDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             19983..20423
                     /locus_tag="ctg4_165"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGAEMEASRITECIEDLKRLHEVLNEI"
     CDS             20436..21503
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_166"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 4.5e-11,
                     bitscore: 36.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDREYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLARLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATQARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMAKLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             21508..23103
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_167"
                     /sec_met_domain="MFS_1 (E-value: 4.8e-13, bitscore: 42.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAKTGSM
                     DVIMVCSFYMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIAILFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIALFIHRQRTQGKPFVSLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFGEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(23198..24202)
                     /locus_tag="ctg4_168"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTEPDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGV
                     MKELPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
ORIGIN
        1 aagtatcaat aaagtatcgt gttgtctatc ccattcaaag tcgtcggcta tgaagccaac
       61 gctatttccc cttccgaaag agggaaagcg agaccgggca cgtgcgtacc acacaattaa
      121 cattctttaa tcgattgtgc gtagggagat cagaccattt cactgtcatc ttaataaacg
      181 atctcaagaa gatatataaa gaacccctaa acccaaaaca tgaataaaaa ctaatggata
      241 tgacaacatc ttcccagaag gatattatca atgatattct ttccgccatg caatgttatc
      301 ccgaaaacga agcattcatt attgacgata aacattatac ttatgcccaa ctcggtgaaa
      361 taacagcttc tatcacccat tcgctatcag aaataaaaga tgaaaaaatc ggaatcgtag
      421 cggaaaaccg gattgaaacc tatgctgcta ttctggcagt actagccggc ggaaagacct
      481 atgttatcct gcatcctgcc tacccggaag agcgtaatct caaaatagcc gctctggccg
      541 gactgcgtac tttgctctgt acaagtgaca ctgaccggtc agcattcggc accggacact
      601 tcagaatcat cgatacggac cggctaccgg gaaaaacact gtcagaacag cagtcccatt
      661 catcggacga agaaaggaac gcttatatca tttttacatc gggaagcaca ggcgagccca
      721 aaggagtgcc catcacacgg gctaacttga acgcctttta ccgggcatac agttcgctcg
      781 actggaatct ggatgaacat gatcgcatgt tgcaaatgtt cgaacttaca ttcgatgtat
      841 ccgtagtatc tttactgtat cctcttactt taggtgctgc cgtttatacg gtaggccatc
      901 aggatgtaaa gcacttcaag gtgtttgaac ttctggagaa gtatcaactg acctttgcca
      961 ctgtcactcc ctcactgcta caactccttt caccctactt cgacgaaatc aatctgccct
     1021 ctctgaaata tctgggagta tcggcagaag catcgcaaac cgagctgttg gagcgattca
     1081 gaaaatcggc acccaacgca acgttcatca acctatacgg accgaccgaa gctacgattt
     1141 actgcacctg ttaccgtatt ccagcttcgg acaaatgcaa gcattacaac ggaatggtgg
     1201 ctatcggaaa accatttccc ggcatccgcg ccatcattgc cgacgaagaa ggaaacgagc
     1261 tacctcaagg agagacggga gaactttggg tatccggccg gcaggtaatg aaaggttatc
     1321 tggacgaccc ggaaaaatcg gcattggttc tgatacaccg tcccgacgga caaatctatt
     1381 accggaccgg agacttgtgt attctggatg gcgacgggga tattatttat tgcggacgta
     1441 aagactatca ggtaaaaata cagggtttca ggatagaact gagtgaaata gaatatactg
     1501 cccagtcgtt tttcaagact ccctgcagcg tggctgccgt tccgttgctc tgcgacggaa
     1561 tctgtaacga attgcacctg gccgtcgaga caactgaatg tactcaaagc gcattgatag
     1621 aatatctgaa agaaaaactg cccaaataca tgctgccgaa gcagattcat tgtatttccc
     1681 aatttccggt gaccaatagt aataaaacag accgtaaaaa gattgccgaa ctgataaaag
     1741 agaagaaact ctaaaaacaa taataaatat gaatcgagaa gaagtattaa aacaactaca
     1801 aagcattttc cgtaatatct taaaaaagga caacgtatgt atcgacgaat catctacctc
     1861 aaaagatgta gatggctggg actcgctaac ccacatgcaa attatagctc aaatcgagaa
     1921 acatttcgga gtacgtttca atttcaggga ggtcattaag ttcaagaatg tcggcgattt
     1981 gtgcagtgcc ttattaacca aaatggaata aacgatgcag ttcctctctt ttagtttcct
     2041 ggccctgttt accctctgtt tcttcctcta ctatgcagtc aaaggccgtg cccgcaacct
     2101 catactactg gtaaccagtt gtattttcat cggatggtac tatctgcctt tcctgttgac
     2161 ggcagtagtg gtagcactat tcaccttctt ttgggcacaa tggatggaaa gcagggcaaa
     2221 agccggaaaa aagaccaaac ccgtctatat cgcaggaatc atcgccctga tcggcggatg
     2281 gctccttctt catggcacgg tcatagatga tatcatcttt ccacttggga tgtcatttta
     2341 cacatttcaa gccatcagtt atctgacaga cgtgtactgg caagagcaac gcagcgaaag
     2401 aaactgggtg gatttcctga tctatatgct tttcttcatg aagtttctct ccggccctat
     2461 cgaacggggt ggagacctgt tgccacaatt gaaagatccc cgcccgttca tctactcaaa
     2521 cgcggtgacc ggactgaaat atattttact cggactgatc aagaaactgc tgatagccaa
     2581 tcagatctcc ccacaaacag atgtcatgtt tcattcgatt catgacctct cgggtgtaca
     2641 actgctaatg acttgcctac tctaccctat cgaactgtat gccgattttt cgggttatac
     2701 ggatattgct atcggagggg cctatatgtt cggcatcaag ttgtctccta acttcaaccg
     2761 cccgtttgca gcacgctcga ctgccgactt ctggcgccgt tggcacatgt cactctcctt
     2821 ctgggtacgc gattatctct atgtaccgct aaccgccggt acccgtaact ggggacagtg
     2881 gggaatctac ttcagcctcc tcatcacctt tctcgcattg ggtttgtggc atggggccgg
     2941 attgactttc gccatatacg gcctgattca gggtgtcctt atctgctggg aaatgaaaac
     3001 agctgctttc cgcaataatc tgccccaata tataggaaaa tatgcggccg acagcttgct
     3061 gattgtccgg acttatctat tgttcgcact ctcgcttata ttctttcgtg tacaatcgct
     3121 gagcgatgcc tggtatttct tacggaacat ctcgttcgag gtacattctt cctggaaaga
     3181 aatgaacatc ggcatacgcg atcataattg catcgtagca ggttcggccc tattactagt
     3241 attgatctac gaatattatg catctaagta caacctgatg gaaacacttg aacgccaacc
     3301 cgcatggtta cggtggagtg tctactatct gttggtattc gctctgctga tgttaggcaa
     3361 atttgacacg gaaactttca tctatttaca attttaaccg aaacccttta cgcgcatgct
     3421 acatcattca tcgagaatct cccccaagac acgtttttgc ctgaagttgc ttttactgat
     3481 cctgccgctg atcccgatag tggttgtcta ttttatgttt gatccttata gggtattaca
     3541 cccctacaaa cgattcgacg actctcccat gctactcaac gaagcccatg tgggatggca
     3601 gaattatctg cagaatcgcg attcgatagc ctataactcc tttatactcg gcaactcctg
     3661 taccatggca ttcctgacag gagaatggga aaagtacctg gataagaacg accatgccgt
     3721 acgcttctat gacaacggag aaagcctggg cggcgtccgt caaaagcttc agctgctcga
     3781 ctctgtaggt gcacccctga aaaatgtact aatcgttctg gataaaaaat cactggacaa
     3841 aaacgctcct ttatcgggca acaatcatct gttttcggcc gaagcagccg gcatcagcca
     3901 attgggattc cagttgagat tcctgcagga gttcctttat ccggacagaa tgattcctta
     3961 catagattat ctgatccgac ataagtatgc tccttatatg aaaggggtta taaatccggg
     4021 agatcccgtc agggagcctt acacgaacaa ttttatcaat cccagagaaa aagagatcgc
     4081 gcaagatggc gaaatatact ggagccgtca tgaaaaagaa ttcaagaagc gaacgaatgc
     4141 gggtatggaa gaacttcctg ttatatttgc cagccagatt caggtacttc gctccatcaa
     4201 aaaaatctgc gataagcacc acacgaacct gaagttcatc atcggtccgg attactatca
     4261 gaaaaagacc agccgggaag acataaaaat attgaaggct atactgggtg attccgctgt
     4321 ctgggatttc acgggaatca acgaatacac agccgacata catcattatt acgaacccgg
     4381 tcattatcgt ccgctgctgg gagcacgctt actgaaagcc atttatcagg atcaagacac
     4441 ctgccacagg caataaaagt tcctcccata acagtagcac acacagaaga agagcatcct
     4501 cgatccgaaa gaaataatta tatcaaagaa aacaattata tcacattaaa aacttagatt
     4561 atgaaaaaga ttttattatt gctatccgtc tgcatttcat tttcatcatg ctgtacatta
     4621 ttcagcagtt ccaaacaaga tatcaccttt acgggaatga atggaaccaa aatctacgaa
     4681 gcatcgacca aacagaaaat agcggaaatc aaagaagaca atagtgtcac tgtacaaatc
     4741 aaaaagaaag ggaagacaaa caactagtag ccaaaaagga agggtaccaa acgactccct
     4801 ttgtcctgga atctacattt aacaatgcct gcctgtggaa cattctattt tggccgggct
     4861 ttctggtaga tttgggtacg caaaagatga acaaatggga taacacaatt atcaatatcg
     4921 aaatggagaa agaaaataca gaaaacaaat gatcaaacta taatttcgca tggcactctt
     4981 ctccttccac ggagggagtc gccatacgga atcatgcgac ctacaaggaa ggcataattc
     5041 accacaagtc aacacagagt tttttataaa agttctttag agaataaatc tactctgtga
     5101 gactctgtgc tactccgttg tatatacgag tttcggcaca ctctctatag ttgtttcaat
     5161 tccctgtata atttctgaat gggaagtccc attacattga agtagctgcc ggatatggat
     5221 tctactccga caaaaccgat ccactcctgc acaccatacg aaccggcttt gtccatgggc
     5281 tgatagtgat cgacataata agcgatttca tcttcatcaa gaatcgcaaa acggacatcc
     5341 gtcacggcag cgaaacattt ttgccattct cgggtagtga gacacacacc ggtaatcact
     5401 tggtgcgatt taccggagag gctccgcaac atctctatgg catcctgcct tccaacaggt
     5461 ttgccgagcg ctttgccttc atgccagaca atggtatcgg ctgtgatcaa aagctcttcc
     5521 ggtccgatca tcgactgata ggcggctgcc ttctcacggg ctatgaaaag aggaatctct
     5581 tcaccttgca acgtatcggg ataagattcg tccacatccg gcaaagtttt tactacataa
     5641 tcgacaccca agcccgtcat cagttctttg cgacgcggag aattagaggc caatacgatt
     5701 ttataacgat ctaagttagc aagcatactg ataaataaat aaggtatata ctggaaatca
     5761 ccatccgaaa gcatcatcgg acaaccattg gccttgtgct ttaagcacct gctccaccac
     5821 atcgcgtcca cagccgtatc ctccatcggc atacgaaatg taacgggcaa tcgctttcac
     5881 ctcgggaacc gcatctttgg gacagcaggg caatccgcac tcacgcatca cttccatatc
     5941 gggaacgtca tcgcccatgt agagtatctc ctcgtccgta agtccgtatt tgtcacggaa
     6001 accacgataa tcgtgtatct tcaccgcaga gccgaagtac agatcggata cccccaaccc
     6061 tataaaacgt ttccgcacga catcgctccg cccacctgta ataatagcga tacgaagccc
     6121 tttttttacg gccaattgga tggcataacc gtcttttaca tttaccgtac gcatcggttc
     6181 acccgacgga tgcaaaggga tgacattggc gctcagcact ccgtctacat cgaaagcaag
     6241 tgcctttatc cgggtaaggt cgtaattgat tgtgctcatt tttatttaat gtttcgggat
     6301 tattgtcttt cgtgaatgct tcggctaagc aactcgtata accgctgcat ggcaggatca
     6361 tcggcaagca tccgcaagtg attgccgatc acattctcgt cataacggat ggccggcccg
     6421 gtctgggccg tcttaggttc cagttcgtgc accttacggg cggtttcatc aatcaacggc
     6481 aacatcacgt caaacggcag attgtatttc ttaagcaact cggcagcaag ggcatacatg
     6541 tgattggtga agttacatgt aaacacggca gccagatgga gacttttacg ctgctccgag
     6601 tcggcatcgt acacacggtt ggacagtgta gaggcaatgg ctttcagaaa cgcggcatct
     6661 tctgccgaag aagcctctat gaagaaagga atctccttaa aatctacctc ccgctgcttg
     6721 ctgaaagtct gcatgggata gaacacaccg taatgcgaga catgtccttc ccagacattc
     6781 atcgggatgc tacctgccgt atgcaccatc aatgcctctt cccgcttacc ttcgacaatg
     6841 ccctgaagaa gttcggcaaa ggcggaatct ttcagtgaaa caatatacag cttcgcatac
     6901 gggttcacct ctgcgaggtc tgtcgtatat tcggcttcca ctttctgtgc cagctcgcgg
     6961 gccgactctt ccgtacggct atacacctgt acgatacgaa aacctttccg atataaggct
     7021 tttgccagat tagtggcaag atttccggca ccgataaata cgatcggcgt atcttctata
     7081 cttcttttca tcgtgttgaa atcaaataca atatacctcc gattatcaat aaagccaaag
     7141 gcagcagata accggacatc gaaccaagca acgaaacaat caggccgatg ttcagcacca
     7201 accacaatcc gagcaatacc aagccgacgg atttatcccg cttaataaac aggaaaatca
     7261 ccgcagtgta aagcaaaaga ttatccttat tcatcaccca gggtatcccc aaagtggaaa
     7321 agtgtatcag tttgtcgatc agatagagca cccccatcac aataagggtg actgctgtgg
     7381 ctttgtaggt atctttattg tttgctttta ccgcactcac cgttacttac ctccgaactt
     7441 attaatatgg attttttccc attgcaaatg gtcttcatta aagggtttac gttccatccc
     7501 tttatgcccg atcgctatga cggacaacac ctgcaactgt aaaggaatgt cgagcacacc
     7561 gcgcacaaat tcatcggaag gcatcccggt ggcagtatac cgctcacgca cctgcaccca
     7621 gcaacttccc aatcccaagt cttcggcctg aagctgaatc ataatagagg caatagaagc
     7681 gtcctcaatc catacatcgc tcgccaaggg atcggcagta acgacaatgg ccaatgccgc
     7741 gtcggcaata aaggccgaag cctgctcttt gcaatgtgaa agttcactga gcaacttttt
     7801 atcatcgact gcaataaact gccagctgtt actgcgcttt gaagtaggag ccatcagggc
     7861 cgctttcagc aaagcgacta catcttcctg agaaagttct tctccggtaa atttccgcat
     7921 gctgcggcga ttttttatta gttcactgaa attttccatg tatctatact ttgcattatt
     7981 tgaatatacc gccagtcacc atagaatgca caaacacacg cgaaccgagg taccgcccgg
     8041 catgcccgtc tatataaggt atgccctgca ggactttgca tgaatcggcg cgctccgtgg
     8101 cgattcgagc gcaaagatag gcaatttatt ccactctcgt caactcgccg gtcagtgaat
     8161 cgatgataaa accatgcacc cggacatctt tcggaataag cggatggttc tctatggaac
     8221 gaaccgtgcc cctgacggac ttcaccggat cgtcgaatcc gcccagccac gaattaaaat
     8281 cgaccccgca gtagcgtatc atgtcgattg tttcggactt gattccccgc tttttcatgt
     8341 gagctatcat ttcgtcgctg ttcatgtggc aagcaccgca atcagaatgg gcaatgacca
     8401 tcacttcttc tactcccaac tcgatgatgg ccaccagcag actacggatg acactgccga
     8461 aaggatggga aatgacggca ccggcattct ttataatctt tacgtctcca ttgtgaattc
     8521 ccaaagcggc gggcaacagt tctgtcaggc gggtatccat acaggaaagg atggcgattt
     8581 tcttatcagg atacttgtta gtgatatact tttcgtatcc cctgttctca acgaactttt
     8641 tgttgaattc aagaatttct tctaacataa tcaaaaacgg attttattgt agtatctcca
     8701 caaagatagt cacaaaacga cagctcaaca aaataagccc tgcaaatgtt gtaaagagaa
     8761 ataaaaaatg taaatttgtc ccgatatgcc attaaaactg actacatatt accaaggaag
     8821 tgagattccg gattttcccg gaaccaatac gtttcattcg aaagagctat ttcagatcta
     8881 cgaagaaact ccgggctaca ccccgcttct gattatggct tcggaagacg gaaaacctgt
     8941 tgcgcgactg cttgctgcca tccgcaaaag catccgcatg tttcctcccg ctttcatcaa
     9001 acgctgcgaa atctatggca cgggcgaata tctgatagcg gaagccgaca aggaaaggat
     9061 attcggcgaa atgctggagc acctcaccac ggaggctttg cggaactcgt ttctaataga
     9121 attccgcaat ctggagaacg ccatgttcgg ctacaaatat ttccggtcca acagatactt
     9181 ccctgtcaac tggctgcggg tacgaaactc gcttcacggc atcgaaaacg ccgaacagcg
     9241 tttcagcccc tcccgtatcc gccagatcaa aaaaggcctg aaaaacggag caaaagtaga
     9301 cgaggcacgt acggtagaag agatacgcga attttcgaat atgctgaggc atctctattc
     9361 gtcccgcatc cgtaaacatt ttcccaacat catctttttc caacacatgg acacccggct
     9421 gattcacagc cggcaggcaa agattttcat cgtccgctac aaagacaaaa ttatcggagg
     9481 ctctgcctgt atctattcgg gaaacgatgc ctatctctgg ttttcgggag gtatgcgaaa
     9541 gacctatgcc ttgcaatacc cgggtatact ggctgtatgg aaagccctcc aggatgccca
     9601 tcaaaacgga ttccgccaca tggagttcat ggacgccgga ctcccattta agaagcacgg
     9661 ctatcgtgac ttcgtgctcc gcttcggtgg caagcaaagc agcacccggc gatggttccg
     9721 tttccgctgg caatggctga acgacctgct gatcaaaata tacgtctgaa catccgcctg
     9781 tctcagggat cagcgccaac cctctccgcc ttttaaacca cccccttagg ttttaaacca
     9841 acgatacctg ccttttaaac ccatgcacct taggttttaa acctattttc accataatta
     9901 attgcagaaa aatttcttta ttaaacaaga attgattttc tttgtgctgt tttataccat
     9961 tccgaaaaga cgattaatac caaaatttaa aaatatagtt atgaagattt cacacattga
    10021 acatttgggc attgccgtaa aaagtatcga agaagccctt ccgtattatg aaaacgtttt
    10081 aggtttgaaa tgctacaaca tcgaaactgt agaagatcaa aaagtaagaa cagccttcct
    10141 gaaagtaggt gataccaaaa tcgaattact ggaacccaca tgtccggaaa gtaccatcgc
    10201 gaaattcatt gaaaacaaag gtgcaggtgt tcatcacgta gcattcgcca ttgaagacgg
    10261 cgtagccaat gccctggccg aagccgaaag caaagagatc cgcctgatcg acaaagctcc
    10321 gcgcaaaggt gccgaaggcc tgaacattgc tttccttcac ccgaaatcaa ctctgggcgt
    10381 actgacagaa ctctgcgaac actaaaaaga tgtacgattc ggacgatccg cgccacggac
    10441 aaacggaatt tttctttgca ttaaattccc catccgggtt gtcaatcgtc cggttgtaaa
    10501 tattataacc ctttaaatta agaaaaactc atgagtaacc agcttgaaaa agtaaaagag
    10561 cttattgaac ttcgtgctca ggctcgttta ggtggtggcg aaaaggctat tgaaaaacaa
    10621 cacgccaaag gcaaatatac agcccgcgag cgtattgcac agttgcttga cgaaggtagt
    10681 ttcgaagaac tggatatgtt tgttcaacac agatgtacca atttcggaca agagaaaaaa
    10741 catttcctcg gcgacggtgt ggtaaccggt tatggaacga tagaaggtag attagtatat
    10801 gttttcgcac aagatttcac agtattcggt ggttcactgt cggaaaccat ggcacaaaag
    10861 atctgtaaag taatggatat ggccatgaag atgggtgccc ctgttatcgg tatcaacgac
    10921 tcgggtggcg cacgtattca ggaaggcatc aacgccctgt ccggttatgc tgaaatcttc
    10981 cagcgcaaca tcatggcttc gggtgtcatc ccacagattt caggtatttt cggtccgtgt
    11041 gccggcggtg cggtttactc tcccgccctg acggacttca cgctgatgac ggaaggtaca
    11101 tcttacatgt tcctcaccgg accggctgtt gtgaaaacag taacgggtga agacgtgtct
    11161 caggaagatc tgggtggtgc aagcgtacat gccagcaagt ccggtgtaac tcacttcact
    11221 gccgaaaccg gtgaagaagg tctggcgatt attcgcaagc ttctcagctt tattccgcaa
    11281 aacaacctgg aagaagctcc attggtgaac tgtaccgacc ccatcgaccg tatggacgac
    11341 ctgctgaacg agatcatccc cgacagcccg aacaaaccgt acgatatgta cgaagtgatc
    11401 ggcgccatca tcgataacgg agaattcctg gaagtacaga aagactatgc gaaaaatctt
    11461 attatcggtt ttgcccgtat gaacggacaa tcggtaggtg tggttgccaa tcagcctaaa
    11521 tacctcgccg gagtactcga cagcaatgct tcacgcaaag gtgcacgctt cgttcgcttc
    11581 tgcgacgcat tcaacattcc gctggtgaca ttggtagacg ttccgggatt ccttccaggt
    11641 acgggtcagg aatataatgg tgtaatcctg cacggagcca agttgctgta cgcttatggt
    11701 gaagccactg tgcccaaggt aactgttacc ctgcgtaaat cttacggtgg ttcgcacatc
    11761 gtaatgagtt gcaagcaact ccgcggcgac atgaactatg catggccgac agccgaaatc
    11821 gccgtaatgg gcggtgccgg tgcagtagcg gtattgtatg ccaaagaagc caaagatcag
    11881 gaaaaccctg ctcaattcct ggcagacaag gaagccgagt acactaaact gttcgccaac
    11941 ccgtacaatg cagccaaata cggttacatc gacgatgtta tcgaaccgag aaacactcgt
    12001 ttccgcgtga tccgcgccct gcaacagctg cagaccaaaa aattaaccaa ccctgctaaa
    12061 aagcacggta atattccatt gtaacaaatt aaacatcgat tgttatgaat aagaaaagaa
    12121 tcgggatatt tatcgctctg ctggcaatgg tttgcatggg gctcagggcg caaagtgcca
    12181 ccagtctgag aatcaatgag gttttggtcg tcaacgacca gaactatcag gatgactacg
    12241 gactgcacaa tgcgtggata gagatattca acacctcttt cgcttctgta aatctggaag
    12301 gttgctttct gacgaacgat aaaaacaatc cgaccaaata tcctattccc aaaggcgacg
    12361 tgctgactct gatcaagccg cgccaacatg ctttgttctg ggcagacgga atgcctaacc
    12421 ggggtacgtt ccacgtgaac tttacgctcg acccgaacaa agagaattac attgctttgt
    12481 atgactctaa cggtaaaact ctgattgacg aagtaaccat acccgccggt cagcttgccg
    12541 accgttcata cgctcgcgaa aaagacggaa gtgccaactg ggtagtaaaa ggtgaaggag
    12601 aacacagcta tgtcactccg agcaccaaca atatgactat cgacaaaaac ccgaagatcg
    12661 agaacttcaa gaaacacgac tctatcggta tcggtatggc catcatcgcc atgtcggtcg
    12721 tattcatagg tttggtactc ttgtatcttt cattcaaggc ggtaggtaac gtagcggtca
    12781 gactgggtaa gaaaaacgcg atgaaagcca ccggtatcac cgacaagacg gaagcgaagg
    12841 aaaagaacct gggtagccac acaggtgaag aaaccgccgc gatcgccatg gctttgcatg
    12901 aatacctgaa tgacgctcac gacgttgaag acatgatttt gactatcaac aaagtgaaac
    12961 gcacctactc accctggagt tcgaagatct acacactgcg tcagactccg aaaagataat
    13021 tactaaccct aataaaatga agcaatgaaa caatataaat ataaaatcaa cggcaacctt
    13081 tacaacgtta cagtgaacga tgtagaagat aacatagcca acgttgaagt gaacggaacc
    13141 tcttataaag tagagttgga caagcccgtc aaagccgctc cgaaaccggt gacccgtccg
    13201 gcagccgctc cgaaaacgga aacaggtgct ccggtagtaa ccaaacaacc gacagcttcc
    13261 aaaaaagacg gtgtgaaatc tccgcttccg ggcgttatcc tcgacataaa agtgaaagaa
    13321 ggggataccg tgaagagagg ccagacgatc atcatccttg aggctatgaa gatggaaaac
    13381 aacatcaatg ccaataaaga cggaaaagta gcagaaatta aagttaataa aggagattct
    13441 gtacttgaag gtacagacct cgtaatcatt gaataattat gggagatttc gtatcattct
    13501 tagggaataa ccttgttgac ttctggggat acaccggttt tgcgaacgcg acacccggac
    13561 atcttttcat gttgctaatc ggtctcttct ttatctacct tgccgtagcc aaagaatttg
    13621 aaccgatgct gctgatcccc attggcttcg gtattctgat cggtaatatt ccattcaata
    13681 tggaagccgg attaaaagtg ggtatttacg aagaaggttc ggtactgaac atcctttatc
    13741 aaggagtaac ctccggctgg tatccgccgc tcattttcct tggtatcgga gccatgacgg
    13801 acttctcggc gctgatctcc aaccccaaat tgatgctgat cggagctgct gcgcaattcg
    13861 gtatcttcgg cgcgtatatc attgcactgc tcattgggtt cgaacccaac caggcgggtg
    13921 ctatcggtat cattggcggt gccgacggac cgacggccat cttcctttcg tccaaactgg
    13981 ctcccaacct gatgggtgcc atcgctgtgt cagcctattc ttacatggcg ctggtgccgg
    14041 tgatacagcc acctatcatg cgtgcgctaa ccaccaaaca cgagcgtctg atccgcatga
    14101 aaccaccgag aatagtatcg catacggaaa aagtaatctt ccccatcgtg ggtctgttgc
    14161 ttacatgctt cctggttcct tcgggtctgc ctttgctggg tatgctgttc ttcggtaacc
    14221 ttctgaaaga aagtggagta acccgtcgtt tggcaaatac agccagtggt ccgttgatcg
    14281 atgtgatcac tatcctgttg ggactgactg tgggagcttc tacccaagct tcacaattcc
    14341 tcacctggga ttctatcttg atctttatcc tcggtgcatt ctctttcatc atcgcaacag
    14401 cgtcaggtgt catgtttgtc aaattcttca atctattctt gaagaaaggc aataagatca
    14461 atccgctgat cggtaatgca ggtgtatccg ccgtacccga ctcggcacgt atttcacagg
    14521 taatcggttt ggaatatgat ccgaccaact atctgctgat gcacgccatg ggtcctaacg
    14581 tagcgggggt tatcggttcg gctgtagctg ccggtatcct gctcggattc ctcatgtaaa
    14641 cgatattttt tcattagtaa ggtagacgtc cttcttttcg caaagaaggg cgtctttttt
    14701 ttgcgttaat ctatctaaaa gatattacga atctttcgta gaatggatat ttttactaac
    14761 ttgcggacaa taaaacaata cgtcctatga gaacaagaac aatgaaacca ctcttcctta
    14821 ttttctgtct ttgcctcagt cccctactga tgggccagaa tcaaaacaaa attcaggaag
    14881 caatggcaaa ctatgactac gagactgccg ttgaactgat aaacaaggaa cctcccacca
    14941 tcccactgtt aatgcagaaa gcaaaagccc tgaaaggaat cggcagcaat gcggaagctc
    15001 tacgctccat ccgccaagtg atagcggaag actccaccaa ccaacaggca cacatcgaag
    15061 cagcggaatg ctgtaaagca atggccaagt acaacgatgc gctggactac taccggaaag
    15121 ccatcagcct gaatcccaaa aacaagtatg cccgtttgca attcatcaac ctactttgca
    15181 acaccaaaaa ctatgctgaa gcttttggag aaagttcaat gatgtccgaa acggacagtt
    15241 cggccgtagt gctccaccta caggctcaaa gccttgaagg gatgcaacag atactaccgg
    15301 ctatcggttg ctatgaagtc attcaggata aatatccgga cgattatctg gctgcggcca
    15361 aactcggaaa cctgaacatt gtggctggat atcccgaata tgccatccaa gctaccgaac
    15421 gctataggga acgggactcc accaacctga ttgtcaacca gcaaaacgct ctcgcctact
    15481 gccacgccga acaatatccg acagccatca agcgctatga aaagctgtgc caacaggggg
    15541 acagcagtac acagacctta tactacctgg gagtcagcta ttacgcggat gaatattatt
    15601 acgaagcgca cgcgtgtttc agcaaactgc aaaaagagat ggaagaaaat cccaatctgc
    15661 tctattatct gggacgttgc tgcgccaaga cttcctggaa aaaagaaggc atcgaacacc
    15721 tggagaaagc tatcgaacta accattccca aagacagcac tatgatccga ctttacaaag
    15781 gcttggtaga ttgttgtaaa ctggctcagg atactccaaa gcaaatccag gctctcaaag
    15841 aactgtacaa atatgacaag acgaaccata aacttcttta tgacatcgcc tggaactatt
    15901 catatcaact caaagacaac aaatcggccg aacgttatct gcaggctttc ttaaaaaccc
    15961 gaaaggcgaa tgccaggaaa gaagaaccgg tgagtgagaa aggggaactt gtactcggac
    16021 ttgaaaatta ttacaacgct gccgaaaatt ggctgaaaga cttacagaaa gaaaagttct
    16081 tcaaagaagg aataccgtta gaaagtcaga aacaatagaa tctgtccccc ccccatgaaa
    16141 cattggatac tcctcctcta tctggggttc agcgtagtgc tgcaagccca gaacaccgcc
    16201 tccgttcaag aagcaatggc aaactatgac tataaaacgg tgatcagact gattgatgaa
    16261 gaaagtgcat caccacagtt actcatacag aaagccaaag ctttaaaaag tttagggcgt
    16321 accgccgaag ccctgtccac tttgcaacat atcattatcg agctgcccga aaatcagcag
    16381 gcattggtag aggcagcaga atgttgcagg caattgagca aatttaacga ggccttgggg
    16441 tattatcgga aggtgatgga actcaatccc gaacatattt acgcacactt gcaatacacc
    16501 cgcttgttat acaactatca gcgatacggc gatgcattgc gtgagagtat cgcattggcc
    16561 aggaaagaca gttccgccac cgtattgcga ctgatggcgg aaagcatgga aggagccggc
    16621 atgccggtag aaagtatgtt ttgctatctt tccatcatca ggaaatatcc ctccgactat
    16681 ctctcggtag ctaagctggg cagtatcttc aatacaatga aagattacga aggggcaatt
    16741 gccctgacag aagcataccg ccggacggac agcaccaatg tagaagtgaa ccgtcaaaac
    16801 gcactggcgt attgtctgcg caaagaatat cccaccgcca tcaaacgtta tcaggatctg
    16861 accgcccggg gagacagcac actgctgaca tgttattacc tgggagtcag ctactacgct
    16921 acgaaagaat actataaagc gcgcgattgg ctgctcaaag caaaatcatg ccagtcaccc
    16981 ggcgccaacc tactctacta tttgggacgt tcgtgctcca agacattatg gaaacaagag
    17041 ggaataggat atctgaacca ggctatcgcc ctgactatcc ccgccgacag tatcatggag
    17101 cgcttatact caggcttggc agactgctac aggcaaacca agcaaatccg ggaccaaatc
    17161 aaggctacca aagaacaata caaatatgcc cctgacaagc atattttact ttataacttg
    17221 gcgttcttat cggacaaaat tgaagatact aaagccacag agcattactt gcaggctttt
    17281 ctgcgaacaa aatccaaaca aaatgcagta ctacagcagc cggatgatga cgaagaagaa
    17341 cccacaccct acatagatta ctacaaaagt gccaccaata aattggaaag catccgaaaa
    17401 gagaaattct taaagggaga aaagtgaatt gatcggatag atgcatcgtt tcggacaatt
    17461 caccactgag tgcagacaga gtttcacaga gggagaataa tggaaaataa atttgaagat
    17521 gtgcggtaga aggcacagtg gcacgtaacc gaagtcacat cggcacgcag ccgaaattac
    17581 ggtgctgtgt agataaagtt acggtgctgc gtagccgaag ttacggtgct gcgtagccga
    17641 agttacggtg ctgcgtaatc aaagttacgg tgctgcgtaa tcaaagttac ggtgctgcgt
    17701 aatcaaagtt acggtgctgc gtaatcaaag ttacggtgct gcgtagccga agttacggtg
    17761 ctgcgtagcc gaagctatga cggcatctcc ttttccggac gtcacgttca cctgattgca
    17821 tcgaaaagtg ctccttatcg gttgagctcc atcccggaga attctccaat gaaaacgttt
    17881 gcataaatag atggcacaca gtaagaaaga aaacggaaaa caatccgatg atttacccta
    17941 tattagcaac attaaataat aacgagctaa tatcatgaaa aaattattgt tactcttagg
    18001 ttcattccta ctgtcattaa ccacttatgc agccatgaac atatccaaaa tcgatccgcc
    18061 cttctggttc accggtatga acaatccgga actccagtta atggtatacg gtgaaggcat
    18121 cggccaggca tccgtatcag taaattatcc cggtgtatcg ctcagcagcg tcgtgaaact
    18181 ggaaagcaac aattacctgc ttgtctacct acatctcgat aaagaagtaa agccgggcaa
    18241 gatgcccatc acatttacgg tcggaaagaa gaaattggtg aaagagtacg aattgaaagc
    18301 acgcagcaaa gccggagtcg atcacaaagg ttttgacgca tcggatgcat tatacctgct
    18361 gatgccggac cgttttgcca atggcaatcc ggataacgac cggatagaag gcatggccga
    18421 atataaagtg gaccgcaacg acccgaacgc acgtcacgga ggcgacctgg ccggtatcga
    18481 acaaaatctg gactatttta ccgacttggg agtgaccgca ctctggttca ccccggtact
    18541 cgaaaataat atgaaaggcg gctcatatca cggatatgca acaaccgatt attacaaggt
    18601 agacccacgt ttcggcacta acgaggaata tcgctcactg atagcgaaag cccacaaccg
    18661 gggcattaag gtcgtgatgg acatgatctt caatcattgc ggagtagaac atccctggat
    18721 caaggacatg ccttcaaagg actggttcaa ccatgcggac ttcaagaaca actttgtgca
    18781 aacttcctac aagctgactc cacatgtaga tccgtatgcc tcggagtacg atttcgacca
    18841 gatgaacaac ggctggttcg tggaagccat gcctgacctc aaccaaaaga accctcacgt
    18901 atacaaatac ctcttgcaga acagcctgtg gtggattgag tacgccgata tcgacggcat
    18961 ccggatggac acctacccgt atgccgatta cgatgccatg agcaactgga tgaaagaact
    19021 gaacgaagaa taccccaact acaacacggt gggcgaaacc tgggttaccg aaccggccta
    19081 tacagcctgg tggcagaaag actccaagct ctccgccccg cgcaacagtc acttgaaaac
    19141 agtcatggat ttcagcttct tcgacaaagt caacacggcc aagaatgaac aaacggacac
    19201 ttggttcaaa ggattggacc gtgtctacaa caattttgta tacgattatc tgtatcccaa
    19261 tccggcttcc gtactggctt tcatcgaaaa tcatgacacc gaccgtttct tgggtgaagg
    19321 cgaaaacctc gatatgctga aacaggcctc caccctttta ttgaccaccc gacgcatccc
    19381 gcaactctat tatggaacgg aggtgatgat gaacggagta aagagtaaaa gcgacggcta
    19441 tgtacgaaag gacttcccgg gcggatgggc ggacgataaa gagaatgccc tgactcccga
    19501 gggacgtacc cgattgcaga atgaaagcta taacttctac cgcaacctgc tgaactggcg
    19561 taagggcaac gatgtgatcg ccaaaggcag catgaaacag ttcatggtac agcacggcgt
    19621 atatgcttat gcacgccaat ataaagggaa aacggtattc gtcctgttga acggtacgga
    19681 taaagaagtg aaacttcccc tgaaatacta tgccgaagtg ctgaaagaca agactcaagg
    19741 aaaagacgtc attagcggaa aagtaacggc actcaatgaa gaactgacaa tggcaccccg
    19801 ccaatcgatg gttatagagc tttaatctca caccggttat aaccgcataa gcaaagggca
    19861 caaaggattt cacccgacat cctctgtgcc ctttgtgtag cctaatgcga ataataatag
    19921 tcaaacattt gactattatc ggagaatatt cctacctttg cagcgactaa aagaatacga
    19981 cgatgacaaa caacgaatcg gagcgcgagc tcgtcctaca aaccttacga acctggatgg
    20041 cattccgcca ggccgttcag cgggtactca aacgccacaa cgtggatatg accttcgaga
    20101 tgctgcaagt aatgaactgc ctgtggaaca aacaaggcat cagccagcaa tccctggctg
    20161 agaaaacagc aaaggacaag gcttgcctga ccaatctgat taataatctg gaaaagaaaa
    20221 actgggtgat acggaaagaa ggcccctccg accgccgaaa ccgcctgatt ttcctgacgc
    20281 cccaaggcga agaacttgcc ctcaccgtga aacccctgat caacgatatc tatgcccaaa
    20341 ccggagcaga gatggaggca agccggataa cggaatgcat cgaagacctg aagagactgc
    20401 atgaagtgct caatgagatc taaaagaaat ccgccatgtc cacccatcag ataaagctaa
    20461 aacaattgag aagactgaag ttcaggaaca tctttctcaa cacagtatgc atcctgctgg
    20521 cattggcagg tatttcatgg acagtaaact acttctggaa atacgcccgc tacgagataa
    20581 ccaatgatgc cgtagtggat caatacatcg ctccgctaaa catccggata ccgggctata
    20641 tcaaagaagt acgttttacc gaacaccagt atgttcatgc cggcgacacg ttactgatac
    20701 tggacgaccg ggaataccgg atccggctga aagacgcgga agcggccttg atggatgcct
    20761 tgggatcaaa ggaagtgtta aactccggca tccggacttc aggagtaaat gtagccgtac
    20821 aagaagctaa catagccgaa acactggcac gcctttcaca acaagaagcg gaactgaacc
    20881 gatatacccg gctcctgaaa aagcaggccg tcagccaaca ggattatgaa ctggccaaag
    20941 cgaacttcga agcgactcag gcaagataca acgccctgtt gcgacaaaaa gaagcggccc
    21001 aatcgcagta ttccgaaacc agcaaacgca gtacaggcgc cgaagccaat atcctccgga
    21061 aggaggccga cctggagatg gccaaactaa acctgtcgta taccgttgtc accgcaccct
    21121 atgacggata cacgggacga cgtacacttg aaccgggaca gttcgtacaa ggcggacaaa
    21181 ctctttccta cctggtacgg ggcaatgaca agtgggtgac agccaattat aaagagacac
    21241 aaatagccca tatctatatc gggcaaaaag tccgcatcaa agtagatgct ttcagcggac
    21301 gcacttttca cgggaccgta accgccattt ccgaagccac cggatcgaaa tactccctgg
    21361 taccgaccga caattcggca gggaacttcg tcaaagtgca gcaacgcatt ccggtccgca
    21421 tcgatctcaa tgacgcctca cccgaagaga tggaatgcct ccgtgcaggg atgatggtag
    21481 aaacggaagc ggtccgccct taggcttatg gtgaagctca atctgcctac ccgtccctgg
    21541 gtgcctcaat ggttgggcat cgtgaccatg tttattgtca tctttcccat caccctgctc
    21601 aacggtgcct acacaggaag tatggtcgaa gtatcgaaca cgctgggagt attgagcgaa
    21661 gatattacca tggcttacta ttcagcttcg gtagggatgg ctgttgccta tcccatcgta
    21721 ccgaaaatac gcaccatagc cactccgaaa accttactgc tcactgacct gctgctacag
    21781 atattcttca gcctggtatg cgccaaaacc ggtagtatgg acgtcatcat ggtatgcagt
    21841 ttctatatgg gatttctcaa agccttcgtc atgttggagt tcatcatcct gatccgcccg
    21901 ctcttcagtc cgaaaaacgt acgaagtgaa ttctatgcct acttctaccc catcgttttc
    21961 tccggaggtc agctatcgat ggctatcacc gctcaactgg cctatcacta ccaatggcag
    22021 cacatgtact attttgtcac catcctcttg ctgatcgcca ttctgttcgt catctgtttc
    22081 ttccgctatg caaggcgtcc catgcacatt ccgttcaaag aaatggacgg aagaagcatg
    22141 ttcatcatcg ccaccgcttt cctgctaacg ctctatacat ttacctacgg gaaaacactc
    22201 gattggttcg catccccgaa gatcagagta tatgtattcg tcatcccgct cctgatagct
    22261 cttttcatcc atcggcagcg tacacaaggc aaaccctttg tcagcctgaa accactcttt
    22321 ctgcataaat ccatcatcgg atatggcttc atggtactcg ccatgttcct gacagccacc
    22381 agttcactgg taaccaacta tatgaacagc atcatccggg tagacagcat acacgccaat
    22441 tcgctgagcc tgtggctatt gcccggatat gtggtagggg ccgtcatttg cttctggtgg
    22501 ttccgatggc aacgatggcg gtttcgcttc ctcatttcag gaggtatgtt ctgctacgtc
    22561 atctatctgg ctatcctcta ctttggtatc accccttatg gaacttatga aatgctctac
    22621 ctccccatcc tgttccgggg agtggggatg atggtcatat tcattgcgtt cggtgtgttt
    22681 gttgtcgaag atttagaccc gcgcctgacg ttgtccaatg ccttcttcct gatttcattc
    22741 cgctcagtat tagctccggt cctgtccgct tcgttcttta acaacatgct ttactatctg
    22801 caggcaaagg ggatgaacat tctttcggaa aacatgacgc tgaccaatcc gctggccgaa
    22861 caaaaataca atcaggcatt gagcaatgcc ctggcgcaag ggcacgaatt cggcgaggcc
    22921 ggacaattgg cagccaacag tctgtactcc actttgcagc agcaatccct gttgcttgcc
    22981 ctgaaaaccc taatcggcta tgtactgata ctggcactgg tgattgctgt catcgcagcg
    23041 ttcattcctt tccataaaac gctgaaggtg gctgtagtga agacgggtga cgatatggta
    23101 taatgagaag ggatacaaaa aagccaccca attgcttgag tggcttctta aaatataaat
    23161 taaatcaagt aaaactttta aatactagat ttggaattta ttcagctaac ttgttgtcag
    23221 aacccagcac gttgataatt ttgtgcttgt agagtttttc catattgtcg cgagccggtc
    23281 ccagatattt acgcgggtcg aactcagccg gtttttctgc gaatacctta cggatagcag
    23341 cagtcatagc caggcgagag tctgagtcga tgttgatttt gcaaacagca gacttagcgg
    23401 ctttacgcag ttcctcttca ggaataccga tagcagcttt cagtgcacca ccaaactggt
    23461 tgatagttgc aacctcttct tcaggaactg aagatgatcc gtgaagaacg atagggaatc
    23521 ccggaagttc tttcattaca ccgtccaata cgtcgaatgc caacggagga ggaaccatac
    23581 ggcctgtctt cggatcgatg tggcactgtt ccggagtaaa tttgtaagca ccgtgagaag
    23641 taccgataga gatagccaat gaatcgcaac ctgtcttggt aacgaaatca actacttcgt
    23701 ccggttcagt atatgtgtgg tggtcagaag aaacttcgtc ttctacacct gccaatacgc
    23761 caagttcacc ttctacagtt acatcgaact ggtgagcgta ttcaacaact ttcttagtca
    23821 gagcaacgtt ttcgtcgtaa ggaaggtgag aaccgtcgat cattacagaa gagaagcctg
    23881 agtcgataca gcttttgcaa gtttcgaaag tatctccgtg gtcgaggtgc aaaacgattt
    23941 caggattttt gcagccgagt tcttttgcat attctacagc accctgagcc atgtaacgca
    24001 acaatgtagc gttagcatac tgacgagcac cttttgatac ctgcaaaata accggagact
    24061 tagtttctac agcagccttg atgatagcct gcatctgttc catattgttg aagttgaatg
    24121 cagggattgc atatccaccc ttgatagcct tagcaaacat atctctagtg tttaccagac
    24181 ctaaatcttt gtaattaacc attttgttta aaagtttatt gttagtgaat taaaaattct
    24241 atgcaaaagt aagaataatc ctttgaatag agaaaccctc gggcggaaat atccgtttga
    24301 ggagcgtaat tcaattctat ttcaaattat ttcccatcct ttaagagctg tttgtaatgt
    24361 ctacgtagca aataaaggtt ttttattgtt tcctcatata tataatggta ggcaaatgat
    24421 cgctgtaacc atccaaccac actctgccac catatgtacg caggggtgca cccttatatt
    24481 taccatcctg ctgaaacagg taatcgcgca tgaaaacttc attgtgatca tatttcaatc
    24541 cttttgtggc ttgaagcagc gtgggcgaaa ggatgatctg atcgaacaga ttccatttgc
    24601 cgcgatagag caaagtgccc actcccttat cttccagcg
//
