GCA_026966165.1 - 4 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaHPMBAAOM_1 (original name was: gnl|Prokka|HPMBAAOM_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	RRE-containing	511,401	531,754	polysaccharide C	Saccharide	16%

gnlProkkaHPMBAAOM_2 (original name was: gnl|Prokka|HPMBAAOM_2)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NRPS-like	600,219	642,648

gnlProkkaHPMBAAOM_3 (original name was: gnl|Prokka|HPMBAAOM_3)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	phosphonate	315,310	328,869	polysaccharide B	Saccharide	13%

gnlProkkaHPMBAAOM_27 (original name was: gnl|Prokka|HPMBAAOM_27)

Region	Type	From	To	Most similar known cluster		Similarity
Region 27.1	phosphonate	1	2,110	polysaccharide B	Saccharide	6%

No secondary metabolite regions were found in these records:: gnlProkkaHPMBAAOM_4 (original name was: gnl|Prokka|HPMBAAOM_4); gnlProkkaHPMBAAOM_5 (original name was: gnl|Prokka|HPMBAAOM_5); gnlProkkaHPMBAAOM_6 (original name was: gnl|Prokka|HPMBAAOM_6); gnlProkkaHPMBAAOM_7 (original name was: gnl|Prokka|HPMBAAOM_7); gnlProkkaHPMBAAOM_8 (original name was: gnl|Prokka|HPMBAAOM_8); gnlProkkaHPMBAAOM_9 (original name was: gnl|Prokka|HPMBAAOM_9); gnlProkkaHPMBAAOM_10 (original name was: gnl|Prokka|HPMBAAOM_10); gnlProkkaHPMBAAOM_11 (original name was: gnl|Prokka|HPMBAAOM_11); gnlProkkaHPMBAAOM_12 (original name was: gnl|Prokka|HPMBAAOM_12); gnlProkkaHPMBAAOM_13 (original name was: gnl|Prokka|HPMBAAOM_13); gnlProkkaHPMBAAOM_14 (original name was: gnl|Prokka|HPMBAAOM_14); gnlProkkaHPMBAAOM_15 (original name was: gnl|Prokka|HPMBAAOM_15); gnlProkkaHPMBAAOM_16 (original name was: gnl|Prokka|HPMBAAOM_16); gnlProkkaHPMBAAOM_17 (original name was: gnl|Prokka|HPMBAAOM_17); gnlProkkaHPMBAAOM_18 (original name was: gnl|Prokka|HPMBAAOM_18); gnlProkkaHPMBAAOM_19 (original name was: gnl|Prokka|HPMBAAOM_19); gnlProkkaHPMBAAOM_20 (original name was: gnl|Prokka|HPMBAAOM_20); gnlProkkaHPMBAAOM_21 (original name was: gnl|Prokka|HPMBAAOM_21); gnlProkkaHPMBAAOM_22 (original name was: gnl|Prokka|HPMBAAOM_22); gnlProkkaHPMBAAOM_23 (original name was: gnl|Prokka|HPMBAAOM_23); gnlProkkaHPMBAAOM_24 (original name was: gnl|Prokka|HPMBAAOM_24); gnlProkkaHPMBAAOM_25 (original name was: gnl|Prokka|HPMBAAOM_25); gnlProkkaHPMBAAOM_26 (original name was: gnl|Prokka|HPMBAAOM_26); gnlProkkaHPMBAAOM_28 (original name was: gnl|Prokka|HPMBAAOM_28); gnlProkkaHPMBAAOM_29 (original name was: gnl|Prokka|HPMBAAOM_29); gnlProkkaHPMBAAOM_30 (original name was: gnl|Prokka|HPMBAAOM_30)

Compact view

gnlProkkaHPMBAAOM_1 - Region 1 - RRE-containing

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Location: 511,401 - 531,754 nt. (total: 20,354 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaHPMBAAOM_2 - Region 1 - NRPS-like

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Location: 600,219 - 642,648 nt. (total: 42,430 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

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NRPS/PKS modules

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 600218 - 642648:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg2_513

AMP-binding (12..401): X

nrpys: Ile, Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALFLGVVLK
Nearest Stachelhaus code(s):: Leu or Ile DAIYLGVVLK (59% 8Å match); aIle DALVFGVVLK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaHPMBAAOM_3 - Region 1 - phosphonate

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Location: 315,310 - 328,869 nt. (total: 13,560 nt) Show pHMM detection rules used

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaHPMBAAOM_27 - Region 1 - phosphonate

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Location: 1 - 2,110 nt. (total: 2,110 nt) Show pHMM detection rules used

Region on contig edge.

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1