GCA_026966215.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaNHDONMDH_1 (original name was: gnl|Prokka|NHDONMDH_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	RRE-containing	306,462	326,815	polysaccharide C	Saccharide	20%

gnlProkkaNHDONMDH_8 (original name was: gnl|Prokka|NHDONMDH_8)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	phosphonate	165,790	179,349	polysaccharide B	Saccharide	13%

gnlProkkaNHDONMDH_15 (original name was: gnl|Prokka|NHDONMDH_15)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	NRPS-like	30,044	72,473

gnlProkkaNHDONMDH_17 (original name was: gnl|Prokka|NHDONMDH_17)

Region	Type	From	To	Most similar known cluster		Similarity
Region 17.1	phosphonate	1,130	29,337	polysaccharide A	Saccharide	40%

gnlProkkaNHDONMDH_22 (original name was: gnl|Prokka|NHDONMDH_22)

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	phosphonate	3,548	17,842	polysaccharide B	Saccharide	26%

No secondary metabolite regions were found in these records:: gnlProkkaNHDONMDH_2 (original name was: gnl|Prokka|NHDONMDH_2); gnlProkkaNHDONMDH_3 (original name was: gnl|Prokka|NHDONMDH_3); gnlProkkaNHDONMDH_4 (original name was: gnl|Prokka|NHDONMDH_4); gnlProkkaNHDONMDH_5 (original name was: gnl|Prokka|NHDONMDH_5); gnlProkkaNHDONMDH_6 (original name was: gnl|Prokka|NHDONMDH_6); gnlProkkaNHDONMDH_7 (original name was: gnl|Prokka|NHDONMDH_7); gnlProkkaNHDONMDH_9 (original name was: gnl|Prokka|NHDONMDH_9); gnlProkkaNHDONMDH_10 (original name was: gnl|Prokka|NHDONMDH_10); gnlProkkaNHDONMDH_11 (original name was: gnl|Prokka|NHDONMDH_11); gnlProkkaNHDONMDH_12 (original name was: gnl|Prokka|NHDONMDH_12); gnlProkkaNHDONMDH_13 (original name was: gnl|Prokka|NHDONMDH_13); gnlProkkaNHDONMDH_14 (original name was: gnl|Prokka|NHDONMDH_14); gnlProkkaNHDONMDH_16 (original name was: gnl|Prokka|NHDONMDH_16); gnlProkkaNHDONMDH_18 (original name was: gnl|Prokka|NHDONMDH_18); gnlProkkaNHDONMDH_19 (original name was: gnl|Prokka|NHDONMDH_19); gnlProkkaNHDONMDH_20 (original name was: gnl|Prokka|NHDONMDH_20); gnlProkkaNHDONMDH_21 (original name was: gnl|Prokka|NHDONMDH_21); gnlProkkaNHDONMDH_23 (original name was: gnl|Prokka|NHDONMDH_23); gnlProkkaNHDONMDH_24 (original name was: gnl|Prokka|NHDONMDH_24); gnlProkkaNHDONMDH_25 (original name was: gnl|Prokka|NHDONMDH_25); gnlProkkaNHDONMDH_26 (original name was: gnl|Prokka|NHDONMDH_26); gnlProkkaNHDONMDH_27 (original name was: gnl|Prokka|NHDONMDH_27); gnlProkkaNHDONMDH_28 (original name was: gnl|Prokka|NHDONMDH_28); gnlProkkaNHDONMDH_29 (original name was: gnl|Prokka|NHDONMDH_29); gnlProkkaNHDONMDH_30 (original name was: gnl|Prokka|NHDONMDH_30); gnlProkkaNHDONMDH_31 (original name was: gnl|Prokka|NHDONMDH_31); gnlProkkaNHDONMDH_32 (original name was: gnl|Prokka|NHDONMDH_32); gnlProkkaNHDONMDH_33 (original name was: gnl|Prokka|NHDONMDH_33); gnlProkkaNHDONMDH_34 (original name was: gnl|Prokka|NHDONMDH_34); gnlProkkaNHDONMDH_35 (original name was: gnl|Prokka|NHDONMDH_35); gnlProkkaNHDONMDH_36 (original name was: gnl|Prokka|NHDONMDH_36); gnlProkkaNHDONMDH_37 (original name was: gnl|Prokka|NHDONMDH_37); gnlProkkaNHDONMDH_38 (original name was: gnl|Prokka|NHDONMDH_38); gnlProkkaNHDONMDH_39 (original name was: gnl|Prokka|NHDONMDH_39); gnlProkkaNHDONMDH_40 (original name was: gnl|Prokka|NHDONMDH_40); gnlProkkaNHDONMDH_41 (original name was: gnl|Prokka|NHDONMDH_41); gnlProkkaNHDONMDH_42 (original name was: gnl|Prokka|NHDONMDH_42); gnlProkkaNHDONMDH_43 (original name was: gnl|Prokka|NHDONMDH_43); gnlProkkaNHDONMDH_44 (original name was: gnl|Prokka|NHDONMDH_44); gnlProkkaNHDONMDH_45 (original name was: gnl|Prokka|NHDONMDH_45); gnlProkkaNHDONMDH_46 (original name was: gnl|Prokka|NHDONMDH_46); gnlProkkaNHDONMDH_47 (original name was: gnl|Prokka|NHDONMDH_47); gnlProkkaNHDONMDH_48 (original name was: gnl|Prokka|NHDONMDH_48); gnlProkkaNHDONMDH_49 (original name was: gnl|Prokka|NHDONMDH_49); gnlProkkaNHDONMDH_50 (original name was: gnl|Prokka|NHDONMDH_50); gnlProkkaNHDONMDH_51 (original name was: gnl|Prokka|NHDONMDH_51); gnlProkkaNHDONMDH_52 (original name was: gnl|Prokka|NHDONMDH_52); gnlProkkaNHDONMDH_53 (original name was: gnl|Prokka|NHDONMDH_53); gnlProkkaNHDONMDH_54 (original name was: gnl|Prokka|NHDONMDH_54); gnlProkkaNHDONMDH_55 (original name was: gnl|Prokka|NHDONMDH_55); gnlProkkaNHDONMDH_56 (original name was: gnl|Prokka|NHDONMDH_56); gnlProkkaNHDONMDH_57 (original name was: gnl|Prokka|NHDONMDH_57)

Compact view

gnlProkkaNHDONMDH_1 - Region 1 - RRE-containing

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Location: 306,462 - 326,815 nt. (total: 20,354 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaNHDONMDH_8 - Region 1 - phosphonate

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Location: 165,790 - 179,349 nt. (total: 13,560 nt) Show pHMM detection rules used

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaNHDONMDH_15 - Region 1 - NRPS-like

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Location: 30,044 - 72,473 nt. (total: 42,430 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

No matches found.

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 30043 - 72473:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg15_44

AMP-binding (12..401): X

nrpys: Ile, Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALFLGVVLK
Nearest Stachelhaus code(s):: Leu or Ile DAIYLGVVLK (59% 8Å match); aIle DALVFGVVLK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaNHDONMDH_17 - Region 1 - phosphonate

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Location: 1,130 - 29,337 nt. (total: 28,208 nt) Show pHMM detection rules used

Region on contig edge.

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

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core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
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gnlProkkaNHDONMDH_22 - Region 1 - phosphonate

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Location: 3,548 - 17,842 nt. (total: 14,295 nt) Show pHMM detection rules used

Region on contig edge.

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1