GCA_026966295.1 - 3 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaDHNBBPME_1 (original name was: gnl|Prokka|DHNBBPME_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	phosphonate	1,404,455	1,418,014	polysaccharide B	Saccharide	13%

gnlProkkaDHNBBPME_3 (original name was: gnl|Prokka|DHNBBPME_3)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	NRPS-like	71,942	114,371

gnlProkkaDHNBBPME_6 (original name was: gnl|Prokka|DHNBBPME_6)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	RRE-containing	154,831	175,184	polysaccharide C	Saccharide	16%

No secondary metabolite regions were found in these records:: gnlProkkaDHNBBPME_2 (original name was: gnl|Prokka|DHNBBPME_2); gnlProkkaDHNBBPME_4 (original name was: gnl|Prokka|DHNBBPME_4); gnlProkkaDHNBBPME_5 (original name was: gnl|Prokka|DHNBBPME_5); gnlProkkaDHNBBPME_7 (original name was: gnl|Prokka|DHNBBPME_7); gnlProkkaDHNBBPME_8 (original name was: gnl|Prokka|DHNBBPME_8); gnlProkkaDHNBBPME_9 (original name was: gnl|Prokka|DHNBBPME_9); gnlProkkaDHNBBPME_10 (original name was: gnl|Prokka|DHNBBPME_10); gnlProkkaDHNBBPME_11 (original name was: gnl|Prokka|DHNBBPME_11); gnlProkkaDHNBBPME_12 (original name was: gnl|Prokka|DHNBBPME_12); gnlProkkaDHNBBPME_13 (original name was: gnl|Prokka|DHNBBPME_13); gnlProkkaDHNBBPME_14 (original name was: gnl|Prokka|DHNBBPME_14); gnlProkkaDHNBBPME_15 (original name was: gnl|Prokka|DHNBBPME_15); gnlProkkaDHNBBPME_16 (original name was: gnl|Prokka|DHNBBPME_16); gnlProkkaDHNBBPME_17 (original name was: gnl|Prokka|DHNBBPME_17); gnlProkkaDHNBBPME_18 (original name was: gnl|Prokka|DHNBBPME_18); gnlProkkaDHNBBPME_19 (original name was: gnl|Prokka|DHNBBPME_19); gnlProkkaDHNBBPME_20 (original name was: gnl|Prokka|DHNBBPME_20); gnlProkkaDHNBBPME_21 (original name was: gnl|Prokka|DHNBBPME_21); gnlProkkaDHNBBPME_22 (original name was: gnl|Prokka|DHNBBPME_22); gnlProkkaDHNBBPME_23 (original name was: gnl|Prokka|DHNBBPME_23)

Compact view

gnlProkkaDHNBBPME_1 - Region 1 - phosphonate

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Location: 1,404,455 - 1,418,014 nt. (total: 13,560 nt) Show pHMM detection rules used

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

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KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaDHNBBPME_3 - Region 1 - NRPS-like

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Location: 71,942 - 114,371 nt. (total: 42,430 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

No matches found.

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 71941 - 114371:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg3_91

AMP-binding (12..401): X

nrpys: Leu, Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALFLGVVLK
Nearest Stachelhaus code(s):: Leu or Ile DAIYLGVVLK (59% 8Å match); aIle DALVFGVVLK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaDHNBBPME_6 - Region 1 - RRE-containing

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Location: 154,831 - 175,184 nt. (total: 20,354 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1