LOCUS       c00055_gnlPro..        16402 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JKLADGBJ_59.
ACCESSION   c00055_gnlPro..
VERSION     c00055_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 16:35:00
            Original ID  :: gnl|Prokka|JKLADGBJ_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16402
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16402
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3867:6402]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3868..6402
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..16402
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16402
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             162..476
                     /locus_tag="ctg55_1"
                     /transl_table=11
                     /translation="MKRCKNWVVTIVAFLMLVGEISVLPANLQGSTSVVNAAIHHRRRK
                     HQYRDKTKIYTSNYRIVDNKRSKIFHVMRGHNYRMNRENAVFFKSKAAARAAGYRESKR
                     "
     CDS             complement(517..2817)
                     /locus_tag="ctg55_2"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGKVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNRYIITINFIN"
     CDS             2946..3794
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg55_3"
                     /sec_met_domain="LysR_substrate (E-value: 7e-29, bitscore:
                     92.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 8e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQPKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             3868..5097
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_4"
                     /sec_met_domain="Amidinotransf (E-value: 9.6e-109,
                     bitscore: 355.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELLTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             5108..5539
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_5"
                     /sec_met_domain="OTCace_N (E-value: 2.1e-37, bitscore:
                     120.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             5500..6402
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_6"
                     /sec_met_domain="OTCace (E-value: 2.1e-46, bitscore: 149.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 1e-19, bitscore: 63.1,
                     seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQNFA
                     QDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTP
                     DDQLIFMHCLTAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIK
                     AVMAATLGNLFIPIACGGGGILVIVKDGHLRGVAGVIHKDFSAAKMAEDINADELVILT
                     TVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGSMKPKIEAAIEFVEKTGNLAII
                     TSLSNANKLADGVGTIIYN"
     CDS             6416..6952
                     /locus_tag="ctg55_7"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDINMNI
                     PGPIKNNRYLTKMFMLGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFENQISLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             7068..8234
                     /locus_tag="ctg55_8"
                     /transl_table=11
                     /translation="MELKKNKNNLKQITALIQYAFLKNNDLTKDENFMSRYDHSTGYGY
                     FDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQLMKEILHDLHRQD
                     IPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIVRGKWDNLAVQNG
                     VIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERPISYLIYRIRDNT
                     FLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPEQNELQVDLRPYM
                     MSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRKVAVERKEDALVD
                     FSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDYF"
     CDS             8250..8411
                     /locus_tag="ctg55_9"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             8401..9018
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_10"
                     /sec_met_domain="LysR_substrate (E-value: 5.8e-12,
                     bitscore: 37.5, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNKMTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHD
                     GAFAKLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDM
                     TCFIVAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASRSGYFILNENTARLIN
                     TTDLQPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             9117..9617
                     /locus_tag="ctg55_11"
                     /transl_table=11
                     /translation="MLKRTLLPLTSMVLVLGLTGLASQVETVDASTYGNGVQVTIPKKM
                     QGTWYSYDRNAHNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWM
                     SGKTTKMKNDTFYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKL
                     AKK"
     CDS             9751..10413
                     /locus_tag="ctg55_12"
                     /transl_table=11
                     /translation="MKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTSQENEPGTLFM
                     QTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVELFPEFISTKA
                     EKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAMIAGTVADQPN
                     EWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVDQGAIFYQP"
     CDS             10983..12023
                     /locus_tag="ctg55_13"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKRPA
                     SKSKRVKTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDNRNNY
                     EFDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLI
                     DVLRKM"
     CDS             complement(12216..12590)
                     /locus_tag="ctg55_14"
                     /transl_table=11
                     /translation="MTTKIEKISPKIYKVTDNDKHLGTISTYHNLFHNKYIYLKFNLSD
                     YSVNIPFSKIVQAEHQALQVMIDSNENPIVDFLLRNGFICKRHCYTLTVNKKDLKIEIN
                     NKLSLHFFNTESPDYETHCF"
     CDS             complement(12979..13218)
                     /locus_tag="ctg55_15"
                     /transl_table=11
                     /translation="MKIGIIQATSQKSKNFILEKYIKESVGSNDQVFNFGIYQDSSASL
                     SYVQVSLAVALLINSKATDFIVTGCTSGQGMMLA"
     CDS             13296..13862
                     /locus_tag="ctg55_16"
                     /transl_table=11
                     /translation="MKKIIVGTPVKLSHVLIGMIVVVLLSLFLTGFGYQAWWLFLIVLI
                     LGVFVTLPTCFNPYWQISSENITIINYDINDVIKLMQLLGLHKKSKQVINLSDVKKAAV
                     VYRKNVRLSPIDFNPDYLNLILDLGKGTNMTLTLGNVDYQQLNSIMGLLQDKNIVVDDK
                     QNILQLLRENKNLFNHFHKKGWTSL"
     CDS             13863..14249
                     /locus_tag="ctg55_17"
                     /transl_table=11
                     /translation="MDKEQIIRNYFRAWLSPNLEVVQNTFDENAIYSECYGPVYRNKKE
                     IISWFENWNKQGKVIAWPIERLIINGDTSIAEWHFKCNYQGKISEFDGVSIIEFNDQNK
                     IISVKEYQSKSKHYYPIVNKTFNC"
ORIGIN
        1 tcctactttg attaaataaa taattaaaaa atcaatttac gagaaagaac tatttacaca
       61 aaagatttga cagtttcaaa ctagtttcta ataaacgtag gaacacttca tatataaacg
      121 tatactatat aaatatagtg acatattaag ggagtgtttt tatgaaaaga tgcaagaatt
      181 gggttgtgac tattgttgca tttctgatgt tagtgggaga aatcagtgtt ctgcctgcaa
      241 atttgcaggg gtcgacatca gttgttaatg cagctattca tcacagaagg agaaagcatc
      301 aatatcgtga taaaactaag atttatacca gtaattacag aattgttgat aataaacgat
      361 caaaaatctt tcacgtaatg cgcggtcata attatcgaat gaatcgtgaa aatgcagttt
      421 tcttcaagag taaagcagca gcacgtgcag caggatatcg tgaatcaaaa agataaatta
      481 aaagacttct aagagttcaa agttcctaga agtcttttaa tttataaaat ttatggtaat
      541 aatatacctg tttttcatca caggttggta aattaagtcg attattatgg cagcaataat
      601 cgctacaatt acagtaattg ctaagttttg aatggaaatc tggaccattg cccaaccaca
      661 aagagctaag ataaaggtca atagaacatc tgcaatttga acactaccaa ccaacttgga
      721 tgggtaatct tgccaaaagt acttacgagt tctagtaatc aaaacaatca acattgcgct
      781 aagaactagg tatacgtaaa ccatagtaga aacagcaccg tgactccaac cgtgtgtgtt
      841 taagaaccaa acaaacccaa taccaattaa agtccaacca gcagctagtg aaaaggcgat
      901 cttagcaagc ttagccatat tccagttttc tggcttataa gtaatgtgag tcctgtcagt
      961 tccaatcatc atcgtaacca tattgttcat aatggtatag ataaccattg cattcaaggc
     1021 cattgggatg tagtcaaaga aaagatagcc aaaagttaac agcatcgtta attcagcagt
     1081 tctagcaagc ttggttagtg accaagtagt cattctttgg tatacgcgat gtccagcgtc
     1141 taaaatttta acaattgagc ctagaccatc gtctagtaat accattttac ccgaacgctt
     1201 agctacgtca gcagcatttg aaactgcgat tcctacttca gcttgtttta atgcaggcgc
     1261 gtcgttaact ccgtcacctg tcatccctac gatatagcct ttttcttgga aaagctttac
     1321 catcttgagt ttatcttctg gtaaaacatc agcaataccg gccaaatcat taatatcagt
     1381 attttcattg aaatcgtgaa tcgaaattac tttaccagtt aaatcaactt gttctgccac
     1441 tgcagcagcg gtcttttgat tgtcaccagt taacataatt gggcgaacgc cacgtttctt
     1501 gagttcagcc aaagctgctt tagagtctgt tctaacttta tcttgtaaga tgaagacacc
     1561 agctaactta tcgtcaatca agactgccac tgagcgtcct gccttgaaat taattccaga
     1621 aatttcttca tcggcatgtt tatcgatcaa agataattgc ttaaatgaac caagctttac
     1681 attatgtcca gcaacatcag ccatagaata accagtgtca gaagtaaatg gagtaaagtt
     1741 ttcagcattc atgactggaa tgttattttc tactaagtat tcatcgattg ctgtatcgat
     1801 aataccagca ttacgtttat cagttgcggc tccagctaaa gcaagcacgt ctttgtcagg
     1861 caagtcactt agatcagtcc aagcggctac ggcagttttg ttttccgtaa ttgttccagt
     1921 cttatcaagt aaaagcaagt tcaagttagc tgcgtcctga attccagtta ggtcagaagt
     1981 caggactcct tctttactta agcgggttgc ttcaaatgag ttggataaag caaaagttga
     2041 tggcattgct acaggaattg aagcaataaa catcattgcc aggaatggca acatattaat
     2101 aaaggtattg aaattaccgc ctttgaagaa ggaggcgata ataataacta aggttaaaac
     2161 accatctagt aagcaaaggt agtagataat cttagtcaaa agttgttgta agtgaccagg
     2221 agcagcggaa ttgttgatca aattaatcgt cttaccgctt ctagaatctt tacctgtagc
     2281 agtaacaaca gctaggccat caccttcaac aactgtagta ccggcaaagg cggtgtcatc
     2341 aattgctttc ttaactggtt tagattcacc tgtaattgag ctttcatcac aagctaagtt
     2401 accgtcaaca attttaacat ctgctgcgag tacgtccccg cgtttaagtg agattaaatc
     2461 gcctttaact agttgtttag aatcaagttt gatccacttg ccatcgcgtt caactgatac
     2521 agtaggagtc aacttgtgtg aaatattatt taaaactcgt cttgattgct ttttcttaga
     2581 tgcaccgtta aatgcagcaa ataaaagcat caacaacacg aataatgatt ggacccattt
     2641 gcccaagata cattctagaa ttaaagcagc ttctagaatc caagcggata ggttccataa
     2701 cttagacaag aactctttaa agaaattgta ttcaggctct ggtacttcat ttaagccatc
     2761 ttcttttaag cgcttgtctg cttcggcttg agttaagccg tgaaatttat cagacattat
     2821 tttccctcca aatctacctt aataaggtag cacagatatt gctatgaata aaatactaaa
     2881 atacaatata agatattaaa tattttaata tcactatcaa ttgaaataaa aaaaggataa
     2941 ataatatgaa tctaaaacag ttacgttatt ttctagttgt agcagaagaa aagcagatta
     3001 cagcagctgc taagcgcttg tatattgcac agccaccatt aagctatcaa ttaaaacaat
     3061 tagagaaaga gttgggcgcg caattattta aaagaacggc acatggtatt gagctaactg
     3121 atgtgggaca aatttttcaa agctatgcca atgaaattat ttctctagct caaaatgctg
     3181 aaaaccaagt acataagact atttccggtg aattgggaac gattgcaatt ggaatggcat
     3241 cttcctcaac gggcttgata ccaatgaatt cttttaatga attacgaaaa tattatccgg
     3301 aaatttcttt tgatatttat gaagataata cttatggcat cctggataaa ttagaaaaaa
     3361 agacaatcga tctaggcatt gtacgaacgc cttacaacca gacaggttta aatactaaga
     3421 ctttaacaac tgaaaaaatg atggctatta gtgtagaccc agattttcag ccaaaaaaag
     3481 aattacgcat taaagatcta gcagatcagc cattgattat ttatcgtcgc tttgaggata
     3541 tttttaatca aacttttgca catcatgggc ttaaaccatt ttatgcggtt aagtgtgatg
     3601 attcacggac agcaattact tgggccaaga gaaaaatggg agtagcgcta gtaccagaat
     3661 caattgcgac aacttatgcc caagaaaata tgatcgcaat taaacatgct aattggataa
     3721 cacatttgca gctggtttgg cgtaaagatc atcaagttac acctttaatg aaaaaaatca
     3781 ttgctgcaat atgataatac tgtaactttt acctaattga tccataataa atgtaaacgg
     3841 gtacaataat taatagaagg tggttgaatg tcgagtccga ttcatgttta ttcagaaatt
     3901 ggtaagttaa aaacggtgat gttacatcga ccgggaaaag aactagaaaa tctagcccca
     3961 gatattttgc atcgaatgtt gattgacgat attccttatc tgaagattgc ccaagaagaa
     4021 catgatgctt ttgcgcatgt attgaggcag caggggatca aagtattata tcttgaggat
     4081 ttattagcag aatctttaac agatgagaaa gttcgtcggg cattcttaga tcagttactg
     4141 gatgaatcaa gtattaaaaa acaggatcct ttgcatcaat tattgctgaa ctatctccaa
     4201 gaattgctaa ctaaggaaat ggtaaaaacg gtgattgctg gaattagaaa aagtgcgatt
     4261 cataattcta ccccatcttt agcagatttg gctgaggacc cagattaccc tttttatctt
     4321 gatccaatgc caaatgtata ttttactcga gatcaacagg ctgcaattgg ttcagggatg
     4381 accattaacc ggatgacttt cagagctaga cgacgtgaat cattatttat ggaaacaatt
     4441 ttgaaaaatc atcctgattt caagaacgca actattccag tttggcgtga ccgttatcat
     4501 catggtcgcc ttgagggcgg ggatgaacta gttctaaata accatgtgtt agctgtaggt
     4561 atttcacaac gcacttctgc aactgcaatt actgacttag ctcataattt atttgatcat
     4621 tcaagttatg atacgatttt agcgattaag attccgcaca atcatgctat gatgcacctt
     4681 gatacagttt ttacaatgat taattataat caatttacgg ttcatccctt tattttagat
     4741 aaagccggca aaattgatat ttatgttcta cagcccgatg atcacaacgg tgtaaaaatc
     4801 acagaaaaga atgatttggt gcaggttttg aaagaaaact tacatttaag cgaattggat
     4861 ttaattccaa ctggtggtgg tgatccaatt gccgcaccac gtgaacaatg gaatgacggc
     4921 tcaaatacct tggcaattgc accaggtgaa gtcgttactt atgatcgtaa ttatgtatcc
     4981 aatgatttgc taagaaaaca tggcatcatc gttcatgaga ttcggtctag tgaactctca
     5041 cgtggtcgtg gcggtcctag atgtatgtcg tgtccgttga ttcgtgaaga tttataagag
     5101 gcaaaaaatg aaatatttac aaaatgtttt tcaaggtaga agttttctcg attgtaaaga
     5161 ctatactcca gctgaaattt catatttaat tgattttgca ttacatttaa aagaacttaa
     5221 aaaagagcat atcccacatg aatatctgaa aggtaaaaat attgcactac tttttgaaaa
     5281 agcctcaact aggacgcgat ctgcttttgt agtagcttgt aatgatttag gtgctcatcc
     5341 agaatatcta ggcgcaagcg agatccactt aggtaaaaaa gaaagcgtca aggatacggc
     5401 taaagtccta ggctcaatgt atgatggaat tgaatatcgc ggttttgctc aagaagatgt
     5461 agaagagctg gctaaatatt ctggcgttcc tgtttggaag tgggtgatgg ccgcgataat
     5521 gttgccgaca gtcttttagt ttgtggctca atgttaggtg ttaatgtaca tattgttaca
     5581 cccaagcctt tgtttacaca tcctgatgta caaaaaattg ctcaaaattt tgcccaagat
     5641 tcaggttcaa aaaatttgat cacagatgat attgctcaag gcgttaaagg agccaatgtt
     5701 gtttataccg atgtttgggt ttcgatgggt gaaaatgatt ggtctgaacg aattaaatta
     5761 ttaaagccat atacggtcac aatgaaaatg atgcaaatga ctggtacacc agatgaccaa
     5821 ttgatcttta tgcattgttt gacagctttt catgatcgaa caactcaggt gggagaagaa
     5881 atctatgaaa aatatggctt aaatgagatg gaagtaactg atgaggtctt taattcaaag
     5941 tatgcttggc aatttacaga agctgaaaat cgattgcatt caattaaagc agtgatggcg
     6001 gctactttag gaaatttatt tattccgatt gcctgtggcg gtggtggcat ccttgttatt
     6061 gtgaaagatg ggcatctcag aggtgttgcc ggcgtaattc ataaagattt ttccgctgct
     6121 aaaatggcag aagatatcaa cgctgatgaa ttagtaattc taacaacggt ggatcatgca
     6181 tttttgaatt atggcaaaga aaatcaacaa gcaattggta aaataaaagt tgaacagctc
     6241 aaacaatatc tagcagcagg ttatttcgca gctgggagta tgaagcctaa gatagaagct
     6301 gcaattgaat ttgtagaaaa aacaggtaat ttagcaatta tcacctcttt gagcaatgcc
     6361 aacaaactag cagacggagt cggcacaatc atttataatt aactgggtga taaaaatgaa
     6421 tatttttaat gaaggaaaaa agcaggatat tgcccaagtt ttagcagcta aagataggcg
     6481 agtagctgta caacataaga tttttaataa gtatcctaat caaactctag tcgacattaa
     6541 tatgaatatc ccaggaccaa tcaagaataa tcgctattta actaaaatgt ttatgttggg
     6601 tatcaatgag ctggaaaatg cttggactaa cctaggttat cattttaaat tggtgacaca
     6661 gcttaatgat gatagtggct gtgaaaactt ttatgtatta tctttgtcaa ttgaaaaagt
     6721 aaagcgctca acaattgatt ttgagaatca gatatcattg ggacgtctct ttgatgcaga
     6781 cgtgttggta aaaaataaac aagctgcaat ttcacgcaga gatttgggca ggcagccacg
     6841 taagtgcttt ttatgtgatc gccctgctaa agaatgtgct cgcagccgga gacattcagt
     6901 ggaacagatg caggcattta tctctcagct ttatcaagaa tacgttgcgt aaaataaacc
     6961 gggattttat gattccggtt tatttttatg aaaaatctag ttaaaaattt aaaaaatgaa
     7021 ctaaaatagt aatgaataaa tttatagatg tacgtatagg aataagcatg gaattaaaga
     7081 aaaataagaa taatttaaag caaattacgg cattaattca atatgcattt ttgaaaaata
     7141 atgatttgac taaagacgaa aattttatga gtcgttatga tcatagtaca ggttatggct
     7201 attttgataa ggaaaaatta gctagctata ttatggttaa tcgatttaaa agtgatgttt
     7261 ttgggcatca tttaccgatg gctggaatag gttatgtagc ttcatatcct gagtatcgtg
     7321 gccaaggtca tatttcccaa ttaatgaaag aaattttgca tgacttacat aggcaagata
     7381 ttccgtttgc taacctggca ccattttcgg agagctttta tcgccagtac gggtttagca
     7441 atagtattta tcaaaaagaa tatcgctttg atggaagcgc attgcgtagt tttaaattac
     7501 cacgttctgg tcatatagtg cgtggcaagt gggacaattt agctgttcaa aatggtgtga
     7561 ttcaacttta tgaacgtcaa ctgcatactg atgatgaacg taacacggtt gtacgtgagg
     7621 catggtggtg gaatagactt gattcttatt atcatcaccg caatgtagcc gtttattttg
     7681 acgcggatga gcggccaatt agttacttga tttatcgcat tagagacaat acttttttag
     7741 ctgatgaaat gtacgcaatt acgccgcagg gattactgag tatgtttggt tttatgggtt
     7801 cgcacgcggg cagtgttaag caatttaaaa tgagcgtacc agagaaatcg ttacgagctg
     7861 aactttttcc tgaacaaaac gaactccaag ttgatttgcg tccttatatg atgagtcgaa
     7921 ttattgattt tgaaaaagtt ttggcttgta tgcggccaat gcaagaaggt gattttaatc
     7981 tggaagtcaa tagcgatgaa cagtgtcctt ggaatattgg agtttggcaa ttaagtaatc
     8041 atggacgtaa ggtagcggta gaacgtaagg aagatgcatt ggttgatttt tcgggatcaa
     8101 ttaccgcgtg gacccaggtg ctattaggta gactaaccat gaatgctgct gttaaactag
     8161 gattaattac agattaccgc atcaaaaaat tagatttcgt taaaggcgat gtatcatttt
     8221 atgattattt ttagttgtga ggttaaaaaa tgagtaaaga aaagaaactc aatttaataa
     8281 aattatttgg cattgtagtt agtggtttga atttgatctt ttttgccttg atggcactta
     8341 ataagcatga agatactaag gataaaagaa gagtagcaga agaaggacac gcaccgctgg
     8401 atgaaaaata aaatgacgga attaaagatt gcatattttg accaattagg tcgtaaggaa
     8461 ttagatcagg cagtgcagca ttttgtgtta aaacatccta atgtagatgt aaaactactt
     8521 gcgactagtc atgatggtgc ttttgcaaaa ctgaatgaag atgaagcaga catagcaatc
     8581 aatgatttgc gtgacgagaa tcttaacttt gatgaaacag aattgactca agctggtgta
     8641 atggcaattt tgcccaaggg aatgtatcct aatggcattc aaatgattga aaaagacgag
     8701 ctcaatgata tgacttgttt tattgtggct aaacctgaag aagaggttag tgagctacat
     8761 ttatttaaag atttgtatca aattggcagt caattcatcg cttctaactc ggtcgaagaa
     8821 gcagcactgt tggtcgcctc taggtctggc tattttattt taaatgagaa tacggctagg
     8881 ttaattaata ctacagattt gcagccactt ttcttgcttg atcatggtca gttaataaag
     8941 caaaagataa tggcttttta taagtcaaat tcagcgttaa gtagtgagtt tataaagcta
     9001 ttgcagcaag aatattaatc tgtaaagtta aaaatatctt gtctaagtac tataagatac
     9061 tgtaaaatat attatgaaag cggactcata tattttacat tctggagatg atttttatgc
     9121 taaaaagaac tttgttacct ttaacatcaa tggtacttgt tttaggatta actggtttgg
     9181 ctagtcaagt tgagactgtt gatgcttcaa cttatggtaa tggtgtacag gttactattc
     9241 caaaaaagat gcagggtact tggtactctt atgatcgtaa tgcacataat ggcacaaaga
     9301 tcacctttac tgaacatact gttaatggca aaccaatatt tacccaggag gcttcgacaa
     9361 ttagtgatta cttcaatggt agaattgcta accagaagaa ctttgataag gtaacgcaaa
     9421 actggatgtc tggtaaaact accaaaatga agaatgatac attctatgag attgatccgt
     9481 ggattacttt tgaaaattgg agtctttatc gagtggtacc acaaaccatt aatggtaaaa
     9541 agcataacgt gctggtttat tctagtagat atgatggtgg taactacttc agaagcaaga
     9601 aattagctaa aaaatgaagg actacaagtt taagaaagtt aattacacgt tatagttttg
     9661 tgacatccct taactaaggg atgtttttta ctaatagacg cgataaaatt tagtataata
     9721 atgacaaaat taattcttgg aggagaagtt atgaaattaa aacaaacacc aattttgcgt
     9781 ttatataaac tagaaactaa taaagaggat catgcaaagt tcgttaaggc agggcaacat
     9841 aatatgctta cttctcaaga aaacgaacca ggcacattgt ttatgcagac aagtcatgac
     9901 gaagaaacta ctaattttgt agtagaatgc tatcaagacg aagcaagtta tgatactcat
     9961 gctaattcaa agcaatttaa ggattttact gacgttgcta aagatatttt aactagtcga
    10021 gtaaaggtag aattgtttcc ggaatttatt tctacaaagg cagaaaaact agcagttacc
    10081 ggatcaaatg attatgttat ttatctgact gaaattggtg tttctttagg taagggcgat
    10141 gagtttgctc atgctgtaat gaaagaaatg aaaacggcag tcgaagaaga aaaagatatt
    10201 ttggcaatga ttgcaggaac tgttgccgat caaccaaatg aatggttagc tattgaagtt
    10261 tatcgtaata atgaagctta caagcagcac ttggaaacta agaacttcaa agagtatttg
    10321 aataatacaa aatattgtgt tgaaagtaag agtttacgta agttgcaacc agatgtaatt
    10381 gttgaccaag gtgcaatttt ctaccaacca taaagaataa gacgaaaaga agaccaggct
    10441 atgtggagta cataacctgg tctttctagt tagaggggaa aagatttatt aacatatatt
    10501 attctggttt ttagtggcga tgttttacct ttgctactgc tggtttatta attaatactg
    10561 agctgatggc cattaaacca agcgttaaaa atgatccacc aattaagagt agtttaatca
    10621 aggttctcat tcctttcatc ttaattgatc ttataatagc gaaataatat taagaattta
    10681 tatgtaaaac ctaatggatt agttaagaaa ataaaactag aaaaaaggct ggttagcacg
    10741 taaaatagaa atagagtcaa agtctagtgc aactgcgcat aaaataaagc agtatcgatg
    10801 ggatgctgct tgttttggtt aaaaaataga gaatatgctt gtagcccttt tcgtaaatag
    10861 cgttaatgtt gtaaaatgga aagtgcatta agtttattaa tgagaaaatt gatgtattat
    10921 tgcaaaatag tccgtaatgg ccctttttgt tgtgaaaaaa ttaaaagaat ataggattgg
    10981 aaatgccagg aatagtagag caaacattat tagaacaaca aaatattgat ttaaatgaaa
    11041 tggtaacaat gaatcaaatg attgatcaat tgttgcctaa tgcaagtaaa gaattacaac
    11101 aaaaactaaa gattaaaatt tataactttg tgcgtacacg taaacaacca agtattactg
    11161 tgcgaagaag aaaatatttt aagccggctg ttgctaaatt aattattggt aatgtacaag
    11221 attacgcaga tgcaattgaa cgtcgtgcta aggaagcccc agctaaagag gatgctactg
    11281 ataagaggcc agcttctaaa tctaagcggg ttaagacaat tactaagcgt aagattttag
    11341 ctaaagttat aaagaatgat aagattgata aatctattca aaagaaatta gaggataaga
    11401 ttgcttcaat tgtgaagacc aactttatta agccagttaa caagcgggga agtttttcgg
    11461 ttgaagatgg tgaaaaagtt atagctgaac ttagtccttt ttatcaaaat atcaagattg
    11521 atcaaaagta tcgcaagaat gctgaaaaag cggctgaaaa taaggaaaca gaaactaaag
    11581 aaaagcctga gcaacattct aaggatcaga atgaaagtcg tgaaggtcaa tctaaggact
    11641 ttgagcgtaa gaataatcag aagaatagca ataatcgaaa taataataat caaacgcaaa
    11701 atcaacgtaa gcgacaaaat aagcatcctt ttgagatcag aagagaaaat aataaccgct
    11761 cacgtaataa tcagtctaac cgccgctata ataatcgaaa taattatgat aatcggaata
    11821 attatgaatt tgatgaagct agcggtttgc gtgaacgcta caatacagta atcagaaatt
    11881 acaatcaact ggagcaaaga tataatgctt tgcaagataa atataatcag gctttagatg
    11941 ataaagctag attgatcgaa gaaatgggta agaagaacga agacttacgt cgtgtattga
    12001 tcgacgtttt gcgaaaaatg tagtttttgg taaacaaaga gactagtagt caatttgaat
    12061 tgattactag tcttatttta tgtttatgaa atatgattta gcttaaaaat taaaaaaata
    12121 tgtgtaaaaa attatttttg tgtagtaaga ttaaaggatg ataaatattt ttattaatga
    12181 ttaatggagg agaagtatga gtttaaaaga gctatttaaa agcaatgtgt ttcgtaatcg
    12241 ggactttctg tattgaaaaa atgaagagat aatttgttat tgatctcaat ttttaaatct
    12301 tttttgttaa cggtaagcgt ataacagtgt cgtttgcaga taaaaccatt tcttaataaa
    12361 aaatctacga ttggattttc atttgaatca atcatgactt gcaatgcttg gtgctctgct
    12421 tgaactattt ttgaaaatgg aatatttaca gagtaatcac ttagattgaa ttttagataa
    12481 atatatttgt tatgaaaaag attgtgataa gtagaaatag tgcctagatg cttatcgtta
    12541 tcagttactt tgtagatttt aggagatatt ttttcaattt ttgtagtcat tttttatcct
    12601 tttgataatt gaaattaatt tttgatcggt tccgttttta attatgaagt tataaatcgg
    12661 ttcataattg agcacaggga aaataagatc aggatcaatt ttaggtataa tgtcaatcat
    12721 tgatttctta ctaattacgt tgagattttt aacttcttga gcatttctta tctttctttt
    12781 tgcttgtgaa ggaggataac cttgtcccca aggctgttca aaaagatttt ttatagtctg
    12841 ctcaaaattg atttcaccac tccaacccca attaagtcct agtggaaagg agacaacatt
    12901 gccgttattg atatgaccaa aaagaaaagc atcttgtgga gtggggatat aaccacattg
    12961 aatattagga aaagtatttc atgcaagcat cattccttgt ccagaagtac atcctgtcac
    13021 aatgaagtca gtcgccttgc tattaattaa taatgcgaca gctagggaaa cttgcacgta
    13081 agatagacta gccgaactat cttgataaat accaaaattg aatacttgat cattggatcc
    13141 tacagattct ttgatatact tctctaatat gaaattttta cttttttgcg atgtagcttg
    13201 aataatacct attttcatat ttttaacctc tatagtttat tttttgaaag cgctttataa
    13261 tattatatag gaagtaaagt aagaaggtga acgtgatgaa aaaaattatt gttggaactc
    13321 ctgttaaatt gagccatgtt ttaatcggta tgattgtggt agttttactt tcactatttt
    13381 tgacaggatt tggttatcaa gcttggtggc tattccttat tgtactaatt ttaggtgtat
    13441 ttgtaacttt acctacttgt tttaatccgt attggcagat tagtagcgaa aatattacaa
    13501 ttataaatta tgatattaac gatgtgataa aattgatgca actgctaggg ttacataaaa
    13561 agagtaagca agttattaat ttatctgatg taaagaaagc tgccgttgtc tatcgtaaaa
    13621 atgtacgtct tagtcctatt gactttaatc ctgattattt aaatttgatt ttggatttag
    13681 gtaagggaac aaatatgact ttgacacttg gaaatgtcga ctatcagcaa ctaaattcga
    13741 ttatgggttt gttacaagat aagaatattg tagtagatga taaacaaaat attttgcaac
    13801 ttttaagaga aaataaaaac ttgtttaacc attttcacaa gaaaggctgg acatcgctat
    13861 aaatggataa agagcaaata attagaaatt attttcgagc atggctaagt cctaatcttg
    13921 aagtagtcca aaatacattt gacgaaaatg ctatttatag tgaatgctat ggtccagttt
    13981 acagaaataa aaaggagata atatcttggt ttgaaaattg gaataaacaa ggaaaagtaa
    14041 ttgcttggcc aatagaaaga ctcataatta atggtgatac gagcattgcc gaatggcatt
    14101 ttaaatgtaa ttatcaagga aaaattagtg aattcgatgg tgtatcaatt atagaattta
    14161 atgatcaaaa taagataatt tctgtaaaag aatatcaatc aaagtccaaa cattattatc
    14221 ctatagtaaa taagactttt aactgttaag aggttaaaag tcttattttg aatatgaaat
    14281 cttttataaa ctaatttctg tggaaaaaat taccaagcca gcttcgtttc tttttagcct
    14341 cttcttttcg tcgctgttca cgatcttcta acattgcctt agctagcata tcaactgttt
    14401 gagtcaattg tgcttggtta tctctttgtt gcttatctct aaatgaacta ctgttttgat
    14461 acttattcat taacgtatca tcatcaagcc atttatcaaa gttttcaaca tcaataataa
    14521 aaccggtgct agtttgttgc gatgcaatgt gatattttct aggcaaatat ttaaagtagc
    14581 gatcaagcat agtagaaccg ctgtttttcg ccgtttgatc ggagatttta ttgaaaagtt
    14641 ctttattgat ttgggctttt agccggtcat cttgtttaat aaataagata tcgcttccga
    14701 tttttgcttg attgattaac attccccaat catttcgacc aacaaatagg gagtaatcgt
    14761 aattttcttc aaaatatttg ctgacttggt tatacatatc aaatttatca agtgcagttt
    14821 ttaaaacatg cttgattgga tataagaagt ctctttcaat cttctgcgca tcttcaacac
    14881 taacgttagt aaagaatttt gctaattcaa cttgacaata tttaaaaaga tcatcatttg
    14941 cacgactaaa taagctagtt aatgcagcat tacgttgatc actttcacct gaaaaagtag
    15001 attcaaagct taaataccat aaacgacgca taatttcagg ctttagagaa aattgtgatt
    15061 taatagagct ttcttgtcta ttcatcgtga aaatgaatgc tggtgaggga tgagttaaat
    15121 tacgattgtt agtaacttcc ttgatgaatc tttcaaagta agtacgggtt gtaagctcgg
    15181 gactgacatc atcaatcatt aatggactta caggaccatt tgtatataca tagtcactta
    15241 gcgtgttggt aattgtcata ttgatattac tcttgccaag ggcataattc tttggatcca
    15301 tcattccact atctaagaaa ttatgagcac caattaattt agcggctagt cttttcccta
    15361 gggtggactt accagttcga ccttgtccga ttagtgctgt agcaataggc acgtcttctc
    15421 tagatacatt gcttccagat aattcatata aattgcggat tttccaaagc catggtgatt
    15481 catatagaaa cagcataaag tcacaagctt gccagccttc accaacttct ttgtaagtat
    15541 tatattcatg agtgatatca cagaaaagtt gaagcgcatt ttttaattgc ccttcagtta
    15601 aatcagaagt aataacttca gaagggatgt tatcaccaat tttagaggct tggaataatt
    15661 gaccattatt gtaaaactga acaggaacag ggaagagatc ttcttctttt tcaatttgtg
    15721 atgtatctgc ttttgccttt ttgtcttgac gaataatgtg ctgagtcaag ctatataaat
    15781 cttgcccgat tgtatctagc ttacgtcttt tattgccacc ttcaccaaat aaagtaactg
    15841 tttgagaagc aacgagtttt tcattttcag ataatttctt taattcatca tctttgctgt
    15901 agtggtcgcg atactttttt atctcttcag ctgggagaat aattatgtct ttaccagttg
    15961 aattaggact gtttttgatt tcaagagaag aatcttgcat tacatgaatg cgaagatcgt
    16021 ctttattttt gtcttctaaa taaccagata gttttttagc attaatataa gttgtagcct
    16081 gattaaggtt atcttgaaac atttgttgat agcaattgaa taatggatca gaagtattgc
    16141 cgtaatccca aactaattgt tccatatttt tattaacagc cgtatcggta agattcattg
    16201 aacctgaaaa ggcagagtac ttgctttgat tttccattaa ataaagctta gtgtgaatca
    16261 aattctgttt ggtgaaaaaa agctgtaaac taccatctaa aatacgttta gtgaagggac
    16321 tatcttggtg ttcgtagcta tattcaatca aatcacgacg tttatttaaa atttggtcaa
    16381 ttcttttgcc aattgaattt ga
//
