## Fri May 2 04:14:56 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_027153945.1/GCA_027153945.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_027153945.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_027153945.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs AGEJAFOK_00002 748671.LCRIS_00167 3.61e-60 185.0 2DKPI@1|root,30A82@2|Bacteria,1U6BA@1239|Firmicutes,4IG2X@91061|Bacilli,3F7I5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00003 748671.LCRIS_00166 4.53e-76 227.0 COG2337@1|root,COG2337@2|Bacteria,1U642@1239|Firmicutes,4IFTM@91061|Bacilli,3F6ZN@33958|Lactobacillaceae 91061|Bacilli T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin AGEJAFOK_00005 1033837.WANG_0214 3.75e-48 173.0 COG1672@1|root,COG1672@2|Bacteria,1V0EH@1239|Firmicutes,4HXBI@91061|Bacilli,3F4KW@33958|Lactobacillaceae 91061|Bacilli S PFAM Archaeal ATPase - - - - - - - - - - - - AAA_14,AAA_16,ATPase_2 AGEJAFOK_00006 748671.LCRIS_00162 6.55e-97 282.0 29NU4@1|root,309S8@2|Bacteria,1U5KK@1239|Firmicutes,4IFBH@91061|Bacilli,3F65J@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00007 748671.LCRIS_00161 0.0 1299.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans AGEJAFOK_00012 1545701.LACWKB10_1149 2.38e-32 116.0 29PHI@1|root,30AFP@2|Bacteria,1U6KQ@1239|Firmicutes,4IGDG@91061|Bacilli,3F840@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF771) - - - - - - - - - - - - DUF771 AGEJAFOK_00013 1423767.BALU01000006_gene800 7.62e-41 147.0 COG1846@1|root,COG1846@2|Bacteria,1UPK8@1239|Firmicutes,4IV6I@91061|Bacilli,3F8S8@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_36 AGEJAFOK_00014 891391.LAC30SC_06700 4.74e-30 107.0 COG1476@1|root,COG1476@2|Bacteria,1W6PK@1239|Firmicutes,4I1F3@91061|Bacilli,3F8ZA@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 AGEJAFOK_00015 1423755.BAML01000004_gene413 6.66e-31 113.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli,3F85V@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_19,HTH_3 AGEJAFOK_00017 1545701.LACWKB10_1145 2.63e-194 547.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family int3 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase AGEJAFOK_00018 585524.HMPREF0493_1257 0.0 1213.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,3F4C2@33958|Lactobacillaceae 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,PUD AGEJAFOK_00019 748671.LCRIS_01408 4.14e-113 333.0 COG1609@1|root,COG1609@2|Bacteria,1UVZE@1239|Firmicutes,4I2X3@91061|Bacilli,3F6DT@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding protein domain - - - ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_4 AGEJAFOK_00020 748671.LCRIS_00938 4.29e-137 390.0 COG3548@1|root,COG3548@2|Bacteria,1VNI3@1239|Firmicutes,4HSHZ@91061|Bacilli,3F5J9@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) ybbB - - - - - - - - - - - DUF1211 AGEJAFOK_00021 748671.LCRIS_00937 0.0 945.0 COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,3F53D@33958|Lactobacillaceae 91061|Bacilli S ABC transporter yjcA - - ko:K19350 ko02010,map02010 - - - ko00000,ko00001,ko01504,ko02000 3.A.1.121 - - ABC_tran,ABC_tran_Xtn AGEJAFOK_00022 748671.LCRIS_00936 3.46e-32 117.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 AGEJAFOK_00023 1423758.BN55_00795 1.47e-303 830.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans AGEJAFOK_00024 748671.LCRIS_00624 1.62e-278 761.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,3F3KQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 AGEJAFOK_00026 748671.LCRIS_00622 3.76e-316 861.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F4VG@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane chbC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC AGEJAFOK_00027 748671.LCRIS_00621 5.96e-283 775.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,3F4K8@33958|Lactobacillaceae 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C AGEJAFOK_00028 748671.LCRIS_00620 2.16e-79 240.0 COG3757@1|root,COG3757@2|Bacteria,1V484@1239|Firmicutes,4HQWA@91061|Bacilli,3F4K0@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 lys - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25 AGEJAFOK_00029 748671.LCRIS_00620 6.73e-78 236.0 COG3757@1|root,COG3757@2|Bacteria,1V484@1239|Firmicutes,4HQWA@91061|Bacilli,3F4K0@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 lys - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25 AGEJAFOK_00030 1423748.BALB01000001_gene132 0.0 1069.0 COG0531@1|root,COG0531@2|Bacteria,1VT70@1239|Firmicutes,4HUMC@91061|Bacilli,3FCAG@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 AGEJAFOK_00032 1400520.LFAB_05815 1.14e-99 317.0 COG1807@1|root,COG1807@2|Bacteria,1VTTD@1239|Firmicutes,4HUVZ@91061|Bacilli,3F4G7@33958|Lactobacillaceae 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 AGEJAFOK_00033 272621.LBA1413 1.96e-110 334.0 COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,4HQBN@91061|Bacilli,3FC2R@33958|Lactobacillaceae 91061|Bacilli T GGDEF domain - - 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - 5TM-5TMR_LYT,GGDEF,HisKA_7TM,PAS_4,PAS_8,PAS_9 AGEJAFOK_00034 203123.OEOE_1475 2.64e-46 158.0 290YK@1|root,2ZNKB@2|Bacteria,1V5MF@1239|Firmicutes,4HX21@91061|Bacilli,4AXTN@81850|Leuconostocaceae 91061|Bacilli - - - - - - - - - - - - - - Exosortase_EpsH AGEJAFOK_00035 203123.OEOE_1474 1.67e-136 405.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,4AX5C@81850|Leuconostocaceae 91061|Bacilli M Glycosyl transferase family group 2 icaA - - - - - - - - - - - Chitin_synth_2,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 AGEJAFOK_00036 203123.OEOE_1473 2.21e-34 122.0 COG0720@1|root,COG0720@2|Bacteria,1VEAX@1239|Firmicutes,4HY9S@91061|Bacilli,4AY37@81850|Leuconostocaceae 91061|Bacilli H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS AGEJAFOK_00037 272621.LBA1414 6.91e-118 342.0 COG2200@1|root,COG2200@2|Bacteria,1W185@1239|Firmicutes,4HYC2@91061|Bacilli,3FC2S@33958|Lactobacillaceae 91061|Bacilli T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL AGEJAFOK_00038 891391.LAC30SC_03655 5.12e-199 554.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 AGEJAFOK_00039 748671.LCRIS_00731 0.0 1023.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 AGEJAFOK_00040 748671.LCRIS_00730 0.0 1273.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts33BCA - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC AGEJAFOK_00041 748671.LCRIS_00729 3.42e-194 539.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain bglG5 - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD AGEJAFOK_00042 748671.LCRIS_00728 1.25e-262 721.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli,3F3V2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase AGEJAFOK_00043 748671.LCRIS_00727 3.07e-112 321.0 COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli,3F74A@33958|Lactobacillaceae 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc AGEJAFOK_00044 748671.LCRIS_00726 2.85e-153 432.0 29NKW@1|root,309IV@2|Bacteria,1U56K@1239|Firmicutes,4IEXT@91061|Bacilli,3F4Y0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00045 748671.LCRIS_00725 3.23e-98 285.0 COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,4HP8S@91061|Bacilli,3FBNQ@33958|Lactobacillaceae 91061|Bacilli K Penicillinase repressor copY - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R AGEJAFOK_00046 748671.LCRIS_00724 8.04e-190 527.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 AGEJAFOK_00047 748671.LCRIS_00723 0.0 883.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,3F3W5@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV AGEJAFOK_00048 748671.LCRIS_00722 1.6e-220 609.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,3F41C@33958|Lactobacillaceae 91061|Bacilli S YbbR-like protein ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR AGEJAFOK_00049 748671.LCRIS_00721 2.13e-194 540.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,3F4N3@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N AGEJAFOK_00050 748671.LCRIS_00720 3.46e-266 728.0 COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli,3F3W1@33958|Lactobacillaceae 91061|Bacilli P ABC transporter potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSB619.SA_RS05395 SBP_bac_8 AGEJAFOK_00051 748671.LCRIS_00719 3.69e-170 478.0 COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli,3F3ZN@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 AGEJAFOK_00052 748671.LCRIS_00718 8.77e-173 484.0 COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli,3F4CM@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 AGEJAFOK_00053 748671.LCRIS_00717 1.25e-263 722.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,3F40H@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 AGEJAFOK_00054 748671.LCRIS_00716 2.84e-208 576.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,3F40T@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C AGEJAFOK_00055 748671.LCRIS_00715 1.51e-127 362.0 COG0847@1|root,COG0847@2|Bacteria,1V57H@1239|Firmicutes,4HI1V@91061|Bacilli,3F42Z@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T AGEJAFOK_00056 748671.LCRIS_00714 4.82e-113 324.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,3F3MR@33958|Lactobacillaceae 91061|Bacilli O Hydrolase, P-loop family ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE AGEJAFOK_00057 748671.LCRIS_00713 1.1e-232 640.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,3F3MW@33958|Lactobacillaceae 91061|Bacilli C phosphate acetyltransferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB AGEJAFOK_00058 748671.LCRIS_00712 1.64e-174 485.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,3F3W0@33958|Lactobacillaceae 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG AGEJAFOK_00059 748671.LCRIS_00711 2.81e-200 555.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,3F58Y@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase ycsE - - - - - - - - - - - Hydrolase_3 AGEJAFOK_00060 748671.LCRIS_00710 3.07e-124 353.0 29NVF@1|root,309TI@2|Bacteria,1U5NS@1239|Firmicutes,4IFDC@91061|Bacilli,3F68I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00061 1033837.WANG_1103 1.18e-253 695.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HAYI@91061|Bacilli,3FB5V@33958|Lactobacillaceae 91061|Bacilli L COG2826 Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve AGEJAFOK_00062 748671.LCRIS_00709 5.46e-183 508.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,3F494@33958|Lactobacillaceae 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM AGEJAFOK_00063 748671.LCRIS_00708 2.86e-286 782.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,3F3SC@33958|Lactobacillaceae 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK AGEJAFOK_00064 748671.LCRIS_00707 2.86e-244 671.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,3F3JS@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N AGEJAFOK_00065 748671.LCRIS_00706 9.26e-241 662.0 COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,3F53Y@33958|Lactobacillaceae 91061|Bacilli K Putative sugar-binding domain cggR - - ko:K05311 - - - - ko00000,ko03000 - - - Sugar-bind AGEJAFOK_00067 748671.LCRIS_00705 0.0 999.0 2FIUN@1|root,34AK2@2|Bacteria,1W1FZ@1239|Firmicutes,4HYXZ@91061|Bacilli,3F4QI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Big_3,SH3_8 AGEJAFOK_00068 748671.LCRIS_00704 0.0 943.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HBIP@91061|Bacilli,3FCAH@33958|Lactobacillaceae 91061|Bacilli E amino acid ycaM - - - - - - - - - - - AA_permease_2 AGEJAFOK_00069 748671.LCRIS_00971 0.0 996.0 COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,4HAE1@91061|Bacilli,3F4EA@33958|Lactobacillaceae 91061|Bacilli H Citrate (pro-3S)-lyase alpha chain citF - 2.8.3.10 ko:K01643 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - CitF AGEJAFOK_00070 748671.LCRIS_00970 1.79e-214 592.0 COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,4HD40@91061|Bacilli,3F47Q@33958|Lactobacillaceae 91061|Bacilli G Belongs to the HpcH HpaI aldolase family citE - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI AGEJAFOK_00071 748671.LCRIS_00969 1.6e-59 184.0 COG3052@1|root,COG3052@2|Bacteria,1VEZZ@1239|Firmicutes,4HNXD@91061|Bacilli,3F7FR@33958|Lactobacillaceae 91061|Bacilli C Covalent carrier of the coenzyme of citrate lyase citD - - ko:K01646 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001 - - - ACP AGEJAFOK_00072 748671.LCRIS_00968 5.17e-249 684.0 COG3053@1|root,COG3053@2|Bacteria,1TSGQ@1239|Firmicutes,4HC6Q@91061|Bacilli,3F4H7@33958|Lactobacillaceae 91061|Bacilli H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase citC - 6.2.1.22 ko:K01910 ko02020,map02020 - R04449 RC00012,RC00039 ko00000,ko00001,ko01000 - - - Acetyltransf_10,Citrate_ly_lig AGEJAFOK_00073 748671.LCRIS_00967 2.43e-196 543.0 COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,4HMJ7@91061|Bacilli,3F4FI@33958|Lactobacillaceae 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 AGEJAFOK_00075 1423748.BALB01000020_gene1615 3.68e-176 499.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,3F4X5@33958|Lactobacillaceae 91061|Bacilli H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 AGEJAFOK_00076 1423748.BALB01000020_gene1616 3.05e-110 320.0 COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,3F6M0@33958|Lactobacillaceae 91061|Bacilli H Riboflavin synthase ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08950,iYO844.BSU23270 Lum_binding AGEJAFOK_00077 748671.LCRIS_00928 3.09e-289 789.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,3F4EB@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08945 DHBP_synthase,GTP_cyclohydro2 AGEJAFOK_00078 748671.LCRIS_00927 1.91e-103 299.0 COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,3F70X@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08940 DMRL_synthase AGEJAFOK_00079 257314.LJ_1163 2.09e-105 310.0 COG0670@1|root,COG0670@2|Bacteria,1V66F@1239|Firmicutes,4IR6X@91061|Bacilli,3FBMP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the BI1 family ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I AGEJAFOK_00080 748671.LCRIS_00889 3.54e-94 278.0 COG2188@1|root,COG2188@2|Bacteria,1V0UW@1239|Firmicutes,4HI7E@91061|Bacilli,3F4BH@33958|Lactobacillaceae 91061|Bacilli K UTRA domain - - - ko:K03492 - - - - ko00000,ko03000 - - - GntR,UTRA AGEJAFOK_00081 748671.LCRIS_00888 0.0 1006.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family pbg4 - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 AGEJAFOK_00082 525365.HMPREF0548_0922 2.06e-111 324.0 COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,3F4B1@33958|Lactobacillaceae 91061|Bacilli L DNA alkylation repair enzyme alkD - - - - - - - - - - - DNA_alkylation AGEJAFOK_00083 748671.LCRIS_00885 3.14e-226 622.0 COG1957@1|root,COG1957@2|Bacteria,1TRGU@1239|Firmicutes,4H9TZ@91061|Bacilli,3F3V1@33958|Lactobacillaceae 91061|Bacilli F inosine-uridine preferring nucleoside hydrolase iunH - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro AGEJAFOK_00084 748671.LCRIS_00884 4.49e-108 312.0 2F7PX@1|root,34049@2|Bacteria,1UFVR@1239|Firmicutes,4IEZD@91061|Bacilli,3F548@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00085 748671.LCRIS_00883 1.83e-54 170.0 COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,4IT3F@91061|Bacilli,3F7II@33958|Lactobacillaceae 91061|Bacilli C FMN_bind - - - - - - - - - - - - FMN_bind AGEJAFOK_00086 748671.LCRIS_01380 9.46e-159 444.0 COG1760@1|root,COG1760@2|Bacteria,1V8XQ@1239|Firmicutes,4HJWN@91061|Bacilli,3FC4T@33958|Lactobacillaceae 91061|Bacilli E Serine dehydratase beta chain - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_beta AGEJAFOK_00087 748671.LCRIS_01381 7.73e-199 552.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,3F3X8@33958|Lactobacillaceae 91061|Bacilli E L-serine dehydratase, iron-sulfur-dependent, alpha subunit sdaAA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha AGEJAFOK_00088 748671.LCRIS_01382 6.51e-69 208.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - FeS_assembly_P AGEJAFOK_00089 748671.LCRIS_01383 5.01e-150 422.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 AGEJAFOK_00090 748671.LCRIS_01384 7.68e-63 194.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 AGEJAFOK_00091 748671.LCRIS_01388 1.43e-309 843.0 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HAU5@91061|Bacilli,3F3N3@33958|Lactobacillaceae 91061|Bacilli C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases lctO - 1.13.12.4 ko:K00467,ko:K10530 ko00620,map00620 - R00319 RC01312 ko00000,ko00001,ko01000 - - - FMN_dh AGEJAFOK_00092 748671.LCRIS_01236 0.0 1491.0 COG3886@1|root,COG3886@2|Bacteria,1UJK2@1239|Firmicutes,4HWPF@91061|Bacilli,3FBV9@33958|Lactobacillaceae 91061|Bacilli L PLD-like domain - - - - - - - - - - - - PLDc_2 AGEJAFOK_00093 257314.LJ_1253 5.97e-55 174.0 COG3631@1|root,COG3631@2|Bacteria,1V76Z@1239|Firmicutes,4HP66@91061|Bacilli,3F8AB@33958|Lactobacillaceae 91061|Bacilli S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 AGEJAFOK_00094 748671.LCRIS_01237 6.13e-70 216.0 COG1396@1|root,COG1396@2|Bacteria,1V873@1239|Firmicutes,4HQNH@91061|Bacilli,3F762@33958|Lactobacillaceae 91061|Bacilli K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 AGEJAFOK_00095 257314.LJ_1252 8.71e-31 112.0 COG0698@1|root,COG0698@2|Bacteria,1TQQJ@1239|Firmicutes,4I3MD@91061|Bacilli,3FA3Z@33958|Lactobacillaceae 91061|Bacilli G Ribose/Galactose Isomerase - - - - - - - - - - - - LacAB_rpiB AGEJAFOK_00096 324831.LGAS_1066 5.51e-35 127.0 2C6BP@1|root,32SQP@2|Bacteria,1VDYG@1239|Firmicutes,4HS7C@91061|Bacilli,3F5TH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00097 748671.LCRIS_00113 2.32e-47 156.0 29PF3@1|root,30AD9@2|Bacteria,1U6HK@1239|Firmicutes,4IG9W@91061|Bacilli,3F7XT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00098 748671.LCRIS_00122 1.76e-233 642.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3V8@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs2 - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N AGEJAFOK_00099 748671.LCRIS_00123 8.37e-161 450.0 COG1309@1|root,COG1309@2|Bacteria,1VZKY@1239|Firmicutes,4HM1C@91061|Bacilli,3F43G@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N AGEJAFOK_00100 748671.LCRIS_00124 1.11e-177 497.0 2CCK0@1|root,309GI@2|Bacteria,1U516@1239|Firmicutes,4IESZ@91061|Bacilli,3F3YE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00101 748671.LCRIS_00125 0.0 918.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnPH2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1,SBP_bac_3 AGEJAFOK_00102 748671.LCRIS_00126 1.01e-170 477.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran AGEJAFOK_00103 748671.LCRIS_00127 7.36e-291 795.0 COG2340@1|root,COG2340@2|Bacteria,1V1IM@1239|Firmicutes,4HRX1@91061|Bacilli,3F3QG@33958|Lactobacillaceae 91061|Bacilli S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,SLH AGEJAFOK_00104 748671.LCRIS_00128 2.43e-263 721.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,3F41Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N AGEJAFOK_00105 748671.LCRIS_00129 2.45e-164 461.0 2EIZT@1|root,33CQY@2|Bacteria,1VN62@1239|Firmicutes,4HRPP@91061|Bacilli,3F5GU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - MerR_1 AGEJAFOK_00106 748671.LCRIS_00130 1.69e-258 710.0 COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,4HCP3@91061|Bacilli,3F3M9@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibE - - - - - - - - - - - YibE_F AGEJAFOK_00107 748671.LCRIS_00131 7.8e-167 468.0 COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,4HBKX@91061|Bacilli,3F3S6@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibF - - - - - - - - - - - YibE_F AGEJAFOK_00108 748671.LCRIS_00132 2.7e-199 551.0 COG0657@1|root,COG0657@2|Bacteria,1V212@1239|Firmicutes,4HGWT@91061|Bacilli,3FBE2@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 AGEJAFOK_00109 748671.LCRIS_00134 0.0 2035.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HEJM@91061|Bacilli,3FC1B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 31 family - - - - - - - - - - - - DUF5110,F5_F8_type_C,Glyco_hydro_31 AGEJAFOK_00110 748671.LCRIS_00135 8.82e-277 756.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 AGEJAFOK_00111 748671.LCRIS_00139 0.0 949.0 COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,4HF7F@91061|Bacilli,3F57U@33958|Lactobacillaceae 91061|Bacilli S Archaea bacterial proteins of unknown function - - - ko:K06921 - - - - ko00000 - - - ATPase_2,DUF234 AGEJAFOK_00113 748671.LCRIS_00141 4.83e-117 334.0 COG3613@1|root,COG3613@2|Bacteria,1VY4Q@1239|Firmicutes,4HXB4@91061|Bacilli,3F5CB@33958|Lactobacillaceae 91061|Bacilli F Nucleoside ntd - 2.4.2.6 ko:K08728 ko00240,map00240 - R02806 RC00063 ko00000,ko00001,ko01000 - - - Nuc_deoxyrib_tr AGEJAFOK_00114 748671.LCRIS_00142 3.77e-113 325.0 COG1762@1|root,COG1762@2|Bacteria,1V8H9@1239|Firmicutes,4HK36@91061|Bacilli,3F4A7@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.200,2.7.1.204 ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279,M00807 R05570,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5,4.A.5.1 - - PTS_EIIA_2 AGEJAFOK_00115 748671.LCRIS_00143 1.24e-191 531.0 COG2365@1|root,COG2365@2|Bacteria,1V851@1239|Firmicutes,4HJB2@91061|Bacilli,3F55V@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 AGEJAFOK_00116 525365.HMPREF0548_1757 9.29e-111 318.0 COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4HNHG@91061|Bacilli,3F4Z0@33958|Lactobacillaceae 91061|Bacilli T universal stress protein usp5 - - - - - - - - - - - Usp AGEJAFOK_00117 1033837.WANG_1706 8.61e-202 561.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,3F3KK@33958|Lactobacillaceae 91061|Bacilli P Phosphonate ABC transporter phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd AGEJAFOK_00118 525365.HMPREF0548_1755 1.67e-175 490.0 COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,3F3SJ@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC GO:0006810,GO:0008150,GO:0015716,GO:0051179,GO:0051234,GO:0071702 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran AGEJAFOK_00119 748671.LCRIS_00148 1.02e-154 437.0 COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,3F58M@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component phnB - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 AGEJAFOK_00120 748671.LCRIS_00149 1.83e-190 529.0 COG3639@1|root,COG3639@2|Bacteria,1V15B@1239|Firmicutes,4IQWU@91061|Bacilli,3F4TN@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 AGEJAFOK_00121 748671.LCRIS_00150 6.82e-139 392.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco AGEJAFOK_00122 748671.LCRIS_00151 5.18e-109 314.0 2CCK1@1|root,309S4@2|Bacteria,1U5KG@1239|Firmicutes,4IFBA@91061|Bacilli,3F64Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00123 748671.LCRIS_00152 0.0 942.0 2EQYH@1|root,33II5@2|Bacteria,1VMH1@1239|Firmicutes,4HUIK@91061|Bacilli,3F5E7@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos AGEJAFOK_00124 748671.LCRIS_00153 0.0 1317.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HA44@91061|Bacilli,3FB65@33958|Lactobacillaceae 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 AGEJAFOK_00125 748671.LCRIS_00154 0.0 886.0 COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HAB0@91061|Bacilli,3F3S7@33958|Lactobacillaceae 91061|Bacilli S ATP-grasp enzyme yxbA - 6.3.1.12 ko:K17810 - - - - ko00000,ko01000 - - - CPSase_L_D2,Dala_Dala_lig_C AGEJAFOK_00126 748671.LCRIS_00155 0.0 1522.0 COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli,3F435@33958|Lactobacillaceae 91061|Bacilli F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD AGEJAFOK_00127 748671.LCRIS_00156 1.35e-180 501.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli,3F46H@33958|Lactobacillaceae 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM AGEJAFOK_00128 748671.LCRIS_00157 1.69e-132 376.0 COG2151@1|root,COG2461@1|root,COG2151@2|Bacteria,COG2461@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - DUF1858,FeS_assembly_P AGEJAFOK_00129 748671.LCRIS_00158 2.19e-292 797.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli,3F45M@33958|Lactobacillaceae 91061|Bacilli S PAS domain XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 AGEJAFOK_00130 748671.LCRIS_01662 6.24e-143 411.0 COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,4HDAB@91061|Bacilli,3F40X@33958|Lactobacillaceae 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 AGEJAFOK_00132 272621.LBA1612 2.52e-06 58.9 COG1511@1|root,COG1511@2|Bacteria,1V0HE@1239|Firmicutes,4HATS@91061|Bacilli,3F508@33958|Lactobacillaceae 91061|Bacilli D Domain of Unknown Function (DUF1542) - - - - - - - - - - - - DUF1542,FIVAR,Gram_pos_anchor,YSIRK_signal AGEJAFOK_00133 1423758.BN55_02795 0.0 911.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HVA4@91061|Bacilli,3F55J@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus - - 3.6.3.6 ko:K01535 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase AGEJAFOK_00134 1033837.WANG_1715 4.36e-46 155.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli 91061|Bacilli P cation transport ATPase - - 3.6.3.2,3.6.3.6,3.6.3.8 ko:K01531,ko:K01535,ko:K01537,ko:K12952 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.2,3.A.3.23,3.A.3.3,3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 AGEJAFOK_00136 748671.LCRIS_00565 0.0 906.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator qacA - - - - - - - - - - - MFS_1 AGEJAFOK_00137 748671.LCRIS_00564 1.02e-115 332.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,3F4MT@33958|Lactobacillaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran AGEJAFOK_00138 748671.LCRIS_00563 3.34e-303 828.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,3F3UJ@33958|Lactobacillaceae 91061|Bacilli F Permease pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease AGEJAFOK_00139 748671.LCRIS_00562 3.55e-28 111.0 COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,4HEX0@91061|Bacilli,3F5K1@33958|Lactobacillaceae 91061|Bacilli K Putative DNA-binding domain - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4,Penicillinase_R AGEJAFOK_00140 891391.LAC30SC_08610 4.56e-24 92.0 COG2826@1|root,COG2826@2|Bacteria,1U749@1239|Firmicutes,4IGYW@91061|Bacilli,3F8YF@33958|Lactobacillaceae 91061|Bacilli L transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - - AGEJAFOK_00141 1033837.WANG_p1034 1.06e-210 584.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve AGEJAFOK_00145 1123314.AUIO01000033_gene52 4.26e-22 100.0 COG2946@1|root,COG2946@2|Bacteria 2|Bacteria L Replication initiation factor - - - ko:K07467 - - - - ko00000 - - - Rep_trans AGEJAFOK_00146 1033837.WANG_1756 0.0 1413.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,3F3XG@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN AGEJAFOK_00147 1423767.BALU01000010_gene390 5.23e-97 282.0 COG1780@1|root,COG1780@2|Bacteria,1VAP4@1239|Firmicutes,4HKFD@91061|Bacilli 91061|Bacilli F NrdI Flavodoxin like nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI AGEJAFOK_00148 1033837.WANG_1754 1.48e-249 684.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,3F3P1@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm AGEJAFOK_00149 525365.HMPREF0548_1872 1.07e-141 400.0 COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,4HDX2@91061|Bacilli,3F51V@33958|Lactobacillaceae 91061|Bacilli L Resolvase, N terminal domain tnpR1 - - - - - - - - - - - HTH_7,Resolvase AGEJAFOK_00150 1033837.WANG_1516 6.91e-92 269.0 29NZE@1|root,309XJ@2|Bacteria,1VY6M@1239|Firmicutes,4HXWC@91061|Bacilli,3F9SI@33958|Lactobacillaceae 91061|Bacilli L IS1381, transposase OrfA - - - - - - - - - - - - AlbA_2,HTH_Tnp_4 AGEJAFOK_00151 1122149.BACN01000113_gene2019 4.87e-96 290.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AGEJAFOK_00152 1423780.LOT_2228 1.17e-38 129.0 29PU7@1|root,30ASC@2|Bacteria,1U71N@1239|Firmicutes,4IGW4@91061|Bacilli,3F8V3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00153 1423780.LOT_2227 4.65e-184 512.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3FB46@33958|Lactobacillaceae 91061|Bacilli D AAA domain - - - - - - - - - - - - AAA_31 AGEJAFOK_00154 944562.HMPREF9102_2161 5.88e-212 592.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,3F55E@33958|Lactobacillaceae 91061|Bacilli S Replication initiator protein A repA - - - - - - - - - - - RepA_N AGEJAFOK_00155 944562.HMPREF9102_2160 1.14e-164 461.0 COG3177@1|root,COG3177@2|Bacteria,1V3AX@1239|Firmicutes,4HVK3@91061|Bacilli,3F4YX@33958|Lactobacillaceae 91061|Bacilli S Fic/DOC family - - - - - - - - - - - - Fic AGEJAFOK_00156 748671.LCRIS_00253 1.79e-74 231.0 COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes,4HIH3@91061|Bacilli,3F5I9@33958|Lactobacillaceae 91061|Bacilli L Resolvase, N-terminal - - - - - - - - - - - - Cauli_VI,MerR,MerR_1,Resolvase AGEJAFOK_00157 748671.LCRIS_00258 4.18e-208 587.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F431@33958|Lactobacillaceae 91061|Bacilli L Putative transposase DNA-binding domain - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon AGEJAFOK_00158 748671.LCRIS_01635 2.92e-204 568.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt AGEJAFOK_00159 748671.LCRIS_01634 1.03e-206 572.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA AGEJAFOK_00160 748671.LCRIS_01633 3.01e-294 803.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,3F4N1@33958|Lactobacillaceae 91061|Bacilli C NADH dehydrogenase yumB GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU32100 Pyr_redox_2 AGEJAFOK_00161 748671.LCRIS_00618 1.41e-51 178.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,3F53U@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind,FMN_red,Shikimate_dh_N AGEJAFOK_00162 324831.LGAS_0931 9.32e-109 323.0 COG5464@1|root,COG5464@2|Bacteria,1TYDT@1239|Firmicutes,4HB9Z@91061|Bacilli,3F4W3@33958|Lactobacillaceae 91061|Bacilli S PD-(D/E)XK nuclease family transposase - - - - - - - - - - - - PDDEXK_2 AGEJAFOK_00163 748671.LCRIS_01631 6.75e-216 596.0 COG0583@1|root,COG0583@2|Bacteria,1V3HS@1239|Firmicutes,4IQPW@91061|Bacilli,3F4HP@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate AGEJAFOK_00164 748671.LCRIS_01630 1.39e-156 439.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,3F5CM@33958|Lactobacillaceae 91061|Bacilli I Acid phosphatase homologues yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 AGEJAFOK_00165 748671.LCRIS_01629 0.0 1651.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,3F46M@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 AGEJAFOK_00166 748671.LCRIS_01628 0.0 944.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,3F404@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C AGEJAFOK_00167 1293597.BN147_06665 3.11e-256 707.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AGEJAFOK_00168 1293597.BN147_06675 4.84e-42 138.0 29PUF@1|root,30ASK@2|Bacteria,1U71Y@1239|Firmicutes,4IGWE@91061|Bacilli,3F8VI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00169 1293597.BN147_06680 9.14e-187 521.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 AGEJAFOK_00170 1293597.BN147_06685 8.73e-205 568.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,3F3NI@33958|Lactobacillaceae 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 AGEJAFOK_00171 1293597.BN147_06690 8.63e-195 541.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,3F412@33958|Lactobacillaceae 91061|Bacilli P Phosphate transport system permease protein PstA pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 AGEJAFOK_00172 1293597.BN147_06695 4.66e-179 498.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - iSB619.SA_RS06920 ABC_tran AGEJAFOK_00173 1293597.BN147_06700 6.07e-138 391.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,3F46W@33958|Lactobacillaceae 91061|Bacilli P Plays a role in the regulation of phosphate uptake - - - ko:K02039 - - - - ko00000 - - - PhoU AGEJAFOK_00174 1293597.BN147_06705 7.72e-156 437.0 COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,4HJMI@91061|Bacilli,3F5D4@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal phoB - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C AGEJAFOK_00175 1293597.BN147_06710 0.0 982.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,3F3W2@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_8,PAS_9,sCache_like AGEJAFOK_00176 748671.LCRIS_00015 0.0 879.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,3F4MW@33958|Lactobacillaceae 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C AGEJAFOK_00177 748671.LCRIS_00014 3.87e-97 283.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,3F68P@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N AGEJAFOK_00178 748671.LCRIS_00013 0.0 1284.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,3F3TY@33958|Lactobacillaceae 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 AGEJAFOK_00181 748671.LCRIS_00289 4.19e-92 270.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,3F6NT@33958|Lactobacillaceae 91061|Bacilli T GAF domain-containing protein ytsP - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 AGEJAFOK_00183 748671.LCRIS_01566 4.95e-164 462.0 COG1767@1|root,COG1767@2|Bacteria,1TQGQ@1239|Firmicutes,4HGCS@91061|Bacilli,3F4SU@33958|Lactobacillaceae 91061|Bacilli H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase citG - 2.4.2.52 ko:K05966 ko02020,map02020 - R09675 RC00049,RC00063 ko00000,ko00001,ko01000 - - - CitG,CitX AGEJAFOK_00184 748671.LCRIS_01574 4.77e-248 683.0 COG1835@1|root,COG1835@2|Bacteria,1V7GP@1239|Firmicutes,4HJ4R@91061|Bacilli,3F42R@33958|Lactobacillaceae 91061|Bacilli I transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - Acyl_transf_3 AGEJAFOK_00185 1423748.BALB01000005_gene690 1.28e-226 629.0 COG1672@1|root,COG1672@2|Bacteria,1V0EH@1239|Firmicutes,4HXBI@91061|Bacilli,3F4KW@33958|Lactobacillaceae 91061|Bacilli S PFAM Archaeal ATPase - - - - - - - - - - - - AAA_22,ATPase_2 AGEJAFOK_00186 1033837.WANG_1534 1.86e-91 279.0 COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae 91061|Bacilli S cog cog1373 - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 AGEJAFOK_00187 748671.LCRIS_00016 1.94e-217 600.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBU5@91061|Bacilli,3FB6H@33958|Lactobacillaceae 91061|Bacilli P ABC transporter, phosphonate, periplasmic substrate-binding protein phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd AGEJAFOK_00188 748671.LCRIS_00017 2.36e-217 600.0 COG1307@1|root,COG1307@2|Bacteria,1V289@1239|Firmicutes,4I3AR@91061|Bacilli,3F4D9@33958|Lactobacillaceae 91061|Bacilli S DegV family degV1 - - - - - - - - - - - DegV AGEJAFOK_00189 585524.HMPREF0493_0174 7.09e-172 503.0 COG1132@1|root,COG1132@2|Bacteria,1UV7Z@1239|Firmicutes,4I2UY@91061|Bacilli,3F5Y3@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran AGEJAFOK_00190 891391.LAC30SC_08125 1.32e-171 488.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon AGEJAFOK_00191 748671.LCRIS_01695 1.45e-36 128.0 COG3212@1|root,COG3212@2|Bacteria,1U5TJ@1239|Firmicutes,4IFHH@91061|Bacilli,3F6H2@33958|Lactobacillaceae 91061|Bacilli S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY AGEJAFOK_00192 748671.LCRIS_01694 1.73e-79 237.0 COG3759@1|root,COG3759@2|Bacteria,1VAVU@1239|Firmicutes,4HQHN@91061|Bacilli,3F7NA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 AGEJAFOK_00193 748671.LCRIS_01693 0.0 1068.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AGEJAFOK_00194 748671.LCRIS_01559 1.21e-207 573.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,3F50K@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 AGEJAFOK_00195 748671.LCRIS_01558 0.0 1365.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F49Q@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase AGEJAFOK_00196 748671.LCRIS_01557 8.43e-73 219.0 COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HKKC@91061|Bacilli,3F822@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0342 family yheA - - - - - - - - - - - Com_YlbF AGEJAFOK_00197 748671.LCRIS_01556 4.24e-289 790.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,3F3PX@33958|Lactobacillaceae 91061|Bacilli L Ser Thr phosphatase family protein yhaO - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 AGEJAFOK_00198 748671.LCRIS_01555 0.0 1514.0 COG0419@1|root,COG4717@1|root,COG0419@2|Bacteria,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,3F3PF@33958|Lactobacillaceae 91061|Bacilli L AAA domain yhaN - - - - - - - - - - - AAA_27 AGEJAFOK_00199 748671.LCRIS_01554 4.53e-239 656.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,3F4SF@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon AGEJAFOK_00201 1250005.PHEL85_2385 9.67e-33 127.0 28KYP@1|root,2ZAE6@2|Bacteria,4NH0Z@976|Bacteroidetes,1HXHH@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function DUF1829 - - - - - - - - - - - - DUF1828,DUF1829 AGEJAFOK_00202 748671.LCRIS_01553 0.0 916.0 29V6Q@1|root,309MR@2|Bacteria,1U5CG@1239|Firmicutes,4IF3N@91061|Bacilli,3F5IP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - SLAP AGEJAFOK_00203 748671.LCRIS_01552 5.74e-96 280.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,3F6AY@33958|Lactobacillaceae 91061|Bacilli G KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase AGEJAFOK_00204 748671.LCRIS_01550 3.12e-196 546.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,3FB3Y@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 AGEJAFOK_00205 748671.LCRIS_01549 1.2e-41 140.0 29P5R@1|root,30A3W@2|Bacteria,1U65N@1239|Firmicutes,4IFVH@91061|Bacilli,3F74E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - YtxH AGEJAFOK_00206 748671.LCRIS_01548 1.61e-101 293.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HJ19@91061|Bacilli,3FCD7@33958|Lactobacillaceae 91061|Bacilli FG Scavenger mRNA decapping enzyme C-term binding hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT AGEJAFOK_00207 748671.LCRIS_01547 3.67e-174 486.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,3F444@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AGEJAFOK_00208 748671.LCRIS_01546 1.63e-281 770.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,3F4HH@33958|Lactobacillaceae 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB AGEJAFOK_00209 748671.LCRIS_01545 2.16e-163 456.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,3F3QM@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 AGEJAFOK_00211 748671.LCRIS_01542 1.35e-71 215.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,3F72K@33958|Lactobacillaceae 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin AGEJAFOK_00212 748671.LCRIS_01541 8.78e-157 439.0 COG0073@1|root,COG0073@2|Bacteria,1V7QA@1239|Firmicutes,4HJBD@91061|Bacilli,3FBJ0@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily XK27_10290 - - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind AGEJAFOK_00213 1033837.WANG_0235 2.59e-313 853.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,3F49J@33958|Lactobacillaceae 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M AGEJAFOK_00214 748671.LCRIS_01539 4.65e-278 764.0 COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,4HEHY@91061|Bacilli,3F3KX@33958|Lactobacillaceae 91061|Bacilli V MATE efflux family protein mepA - - ko:K18908 - M00705 - - ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 - - MatE AGEJAFOK_00215 748671.LCRIS_01538 2.04e-226 624.0 29NRF@1|root,309PE@2|Bacteria,1U5FS@1239|Firmicutes,4IF75@91061|Bacilli,3F5V8@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP AGEJAFOK_00216 405566.lhv_1633 0.0 973.0 COG0308@1|root,COG0308@2|Bacteria,1U6PC@1239|Firmicutes,4HDA6@91061|Bacilli,3F557@33958|Lactobacillaceae 91061|Bacilli M Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 AGEJAFOK_00217 748671.LCRIS_01534 2.43e-239 657.0 29NJD@1|root,309H9@2|Bacteria,1U53C@1239|Firmicutes,4IEUN@91061|Bacilli,3F4BP@33958|Lactobacillaceae 91061|Bacilli S Bacteriocin helveticin-J - - - - - - - - - - - - Helveticin_J AGEJAFOK_00218 748671.LCRIS_01533 1.33e-67 204.0 COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,4HR7A@91061|Bacilli,3F6PK@33958|Lactobacillaceae 91061|Bacilli L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB AGEJAFOK_00219 748671.LCRIS_01532 2.53e-139 399.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli,3F4HV@33958|Lactobacillaceae 91061|Bacilli O prohibitin homologues hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 AGEJAFOK_00220 748671.LCRIS_01532 1.98e-35 127.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli,3F4HV@33958|Lactobacillaceae 91061|Bacilli O prohibitin homologues hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 AGEJAFOK_00221 748671.LCRIS_01531 0.0 1743.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,3F3ZA@33958|Lactobacillaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A AGEJAFOK_00222 748671.LCRIS_01530 7.81e-199 550.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS AGEJAFOK_00223 748671.LCRIS_01529 2.16e-136 386.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,3F6WF@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE AGEJAFOK_00224 748671.LCRIS_01528 1.29e-106 307.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,3F65S@33958|Lactobacillaceae 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone AGEJAFOK_00225 748671.LCRIS_01527 0.0 865.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4HE63@91061|Bacilli,3FB6I@33958|Lactobacillaceae 91061|Bacilli L Replication initiation and membrane attachment dnaB2 - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 AGEJAFOK_00226 748671.LCRIS_01526 1.31e-215 595.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,3F4JK@33958|Lactobacillaceae 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 AGEJAFOK_00227 891391.LAC30SC_08350 0.0 1240.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,3F3TC@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD AGEJAFOK_00228 1423767.BALU01000011_gene295 5.59e-98 286.0 29NRA@1|root,30A5W@2|Bacteria,1U68M@1239|Firmicutes,4IFZH@91061|Bacilli,3F7B3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00231 748671.LCRIS_00562 3.51e-96 293.0 COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,4HEX0@91061|Bacilli,3F5K1@33958|Lactobacillaceae 91061|Bacilli K Putative DNA-binding domain - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4,Penicillinase_R AGEJAFOK_00232 272621.LBA1796 0.0 929.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,3F3QF@33958|Lactobacillaceae 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 AGEJAFOK_00233 272621.LBA1798 2.08e-164 463.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F61S@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg AGEJAFOK_00234 1423767.BALU01000001_gene1435 8.83e-170 479.0 COG3290@1|root,COG3290@2|Bacteria,1V1ET@1239|Firmicutes,4HGNA@91061|Bacilli,3F71I@33958|Lactobacillaceae 91061|Bacilli T GHKL domain - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 AGEJAFOK_00235 1545702.LACWKB8_0357 9.07e-51 168.0 28XJS@1|root,2ZJGW@2|Bacteria,1W4NV@1239|Firmicutes,4I15N@91061|Bacilli,3F6XN@33958|Lactobacillaceae 91061|Bacilli S CRISPR-associated protein (Cas_Csn2) - - - - - - - - - - - - Cas_Csn2 AGEJAFOK_00236 1545701.LACWKB10_0720 4.67e-54 170.0 COG3512@1|root,COG3512@2|Bacteria,1VEH4@1239|Firmicutes,4HNYR@91061|Bacilli,3F7KD@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 AGEJAFOK_00237 1423758.BN55_02655 1.44e-164 466.0 COG1518@1|root,COG1518@2|Bacteria,1TT0J@1239|Firmicutes,4HC5E@91061|Bacilli,3F3RW@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1 AGEJAFOK_00238 1545701.LACWKB10_0722 2.47e-104 341.0 COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4HE0R@91061|Bacilli,3F554@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer cas9 - - ko:K09952 - - - - ko00000,ko01000,ko02048 - - - Cas9-BH,Cas9_PI,Cas9_REC,HNH_4 AGEJAFOK_00239 1423758.BN55_02660 1.5e-93 305.0 COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4HE0R@91061|Bacilli,3F554@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer cas9 - - ko:K09952 - - - - ko00000,ko01000,ko02048 - - - Cas9-BH,Cas9_PI,Cas9_REC,HNH_4 AGEJAFOK_00240 713605.ADHG01000001_gene333 1.59e-108 327.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 AGEJAFOK_00241 1545702.LACWKB8_1670 2.58e-13 69.3 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 AGEJAFOK_00242 324831.LGAS_1687 6.9e-141 400.0 COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,4HBPF@91061|Bacilli,3F529@33958|Lactobacillaceae 91061|Bacilli G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) nanE - 5.1.3.9 ko:K01788 ko00520,map00520 - R02087 RC00290 ko00000,ko00001,ko01000 - - - NanE AGEJAFOK_00243 1114965.Spaf_1050 2.58e-17 80.9 COG3458@1|root,COG3458@2|Bacteria,1TS02@1239|Firmicutes,4HD4X@91061|Bacilli 91061|Bacilli Q acetyl xylan esterase axe1 - 3.1.1.41 ko:K01060 ko00311,ko01130,map00311,map01130 - R03062 RC00020,RC00041 ko00000,ko00001,ko01000 - - - AXE1 AGEJAFOK_00244 1123318.KB904609_gene162 1.4e-74 234.0 COG3458@1|root,COG3458@2|Bacteria,1TS02@1239|Firmicutes,4HD1F@91061|Bacilli 91061|Bacilli Q Acetyl xylan esterase (AXE1) cah - 3.1.1.41 ko:K01060 ko00311,ko01130,map00311,map01130 - R03062 RC00020,RC00041 ko00000,ko00001,ko01000 - - - AXE1 AGEJAFOK_00245 97137.C821_01980 6.48e-279 772.0 COG0591@1|root,COG0591@2|Bacteria,1TQCK@1239|Firmicutes,4HB5K@91061|Bacilli,3F50Z@33958|Lactobacillaceae 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF AGEJAFOK_00246 1235801.C822_01745 1.48e-166 478.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,3F3QK@33958|Lactobacillaceae 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - - - - - - - - - - Na_H_Exchanger AGEJAFOK_00247 1423775.BAMN01000002_gene1901 3.74e-70 222.0 COG1082@1|root,COG1082@2|Bacteria,1VA9Q@1239|Firmicutes,4HJ2W@91061|Bacilli,3F651@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 AGEJAFOK_00248 1400520.LFAB_16590 1.03e-112 333.0 COG1940@1|root,COG1940@2|Bacteria,1TP04@1239|Firmicutes,4HGYM@91061|Bacilli,3F46U@33958|Lactobacillaceae 91061|Bacilli GK ROK family nanK - - - - - - - - - - - ROK AGEJAFOK_00249 1235801.C822_01742 2.65e-154 439.0 COG0329@1|root,COG0329@2|Bacteria,1TQRK@1239|Firmicutes,4HCJ9@91061|Bacilli,3F4KH@33958|Lactobacillaceae 91061|Bacilli EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate nanA - 4.1.3.3 ko:K01639 ko00520,map00520 - R01811 RC00159,RC00600 ko00000,ko00001,ko01000 - - - DHDPS AGEJAFOK_00250 1423775.BAMN01000002_gene1904 1.57e-84 262.0 COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,4HGM0@91061|Bacilli,3F49F@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - iSB619.SA_RS01765 HTH_6,SIS AGEJAFOK_00251 891391.LAC30SC_10540 0.0 917.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AGEJAFOK_00252 1423758.BN55_05395 2.86e-13 64.7 COG1813@1|root,COG1813@2|Bacteria 2|Bacteria K peptidyl-tyrosine sulfation - - - ko:K15773 - - - - ko00000,ko02048,ko03000 - - - HTH_3,HTH_31 AGEJAFOK_00253 866536.Belba_1130 1.28e-09 55.8 COG4226@1|root,COG4226@2|Bacteria,4NSCC@976|Bacteroidetes,47SF5@768503|Cytophagia 976|Bacteroidetes S PFAM HicB family - - - - - - - - - - - - HicB AGEJAFOK_00254 1293597.BN147_03880 1.44e-161 460.0 COG3021@1|root,COG3021@2|Bacteria,1UJID@1239|Firmicutes,4ITAA@91061|Bacilli,3FBV6@33958|Lactobacillaceae 91061|Bacilli S interspecies interaction between organisms - - - - - - - - - - - - Exo_endo_phos AGEJAFOK_00255 272621.LBA1450 6.78e-47 151.0 2B2ZF@1|root,31VKJ@2|Bacteria,1V9FC@1239|Firmicutes,4IVD4@91061|Bacilli,3F82P@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00259 748671.LCRIS_01449 2.09e-205 572.0 2ACE2@1|root,309NT@2|Bacteria,1U5E7@1239|Firmicutes,4IF5H@91061|Bacilli,3F5PN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00260 748671.LCRIS_01450 2.37e-219 605.0 2ACE2@1|root,309I3@2|Bacteria,1U54Z@1239|Firmicutes,4IEW5@91061|Bacilli,3F4PW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00261 748671.LCRIS_01451 0.0 909.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,3F41A@33958|Lactobacillaceae 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N AGEJAFOK_00262 748671.LCRIS_01452 2.05e-286 783.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,3F3PU@33958|Lactobacillaceae 91061|Bacilli P aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase AGEJAFOK_00263 748671.LCRIS_01453 3.84e-216 597.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,3F3XS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT AGEJAFOK_00264 748671.LCRIS_01454 4.95e-89 261.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,3F67E@33958|Lactobacillaceae 91061|Bacilli P Rhodanese-like protein yqhL - - - - - - - - - - - Rhodanese AGEJAFOK_00265 748671.LCRIS_01455 1e-47 152.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,3F83I@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF910) yqgQ - - - - - - - - - - - DUF910 AGEJAFOK_00266 748671.LCRIS_01456 3.25e-154 434.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,3FC8V@33958|Lactobacillaceae 91061|Bacilli S Rhomboid family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 AGEJAFOK_00267 748671.LCRIS_01457 7.92e-126 359.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HKQI@91061|Bacilli,3FC8W@33958|Lactobacillaceae 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig AGEJAFOK_00268 1423748.BALB01000003_gene424 6.25e-29 103.0 COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,3F828@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 AGEJAFOK_00269 748671.LCRIS_01459 0.0 1363.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,3F3KH@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase AGEJAFOK_00270 748671.LCRIS_01460 0.0 1696.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HBW6@91061|Bacilli,3F49G@33958|Lactobacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - YfhO AGEJAFOK_00271 748671.LCRIS_01461 7.04e-218 601.0 COG2971@1|root,COG2971@2|Bacteria,1V38W@1239|Firmicutes,4HGPI@91061|Bacilli,3F5MG@33958|Lactobacillaceae 91061|Bacilli G BadF/BadG/BcrA/BcrD ATPase family - - - - - - - - - - - - BcrAD_BadFG AGEJAFOK_00272 748671.LCRIS_01462 9.43e-52 163.0 29Y69@1|root,30JZN@2|Bacteria,1UMZJ@1239|Firmicutes,4IU45@91061|Bacilli,3F7JJ@33958|Lactobacillaceae 91061|Bacilli S RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB AGEJAFOK_00273 748671.LCRIS_01463 2.74e-69 208.0 COG3041@1|root,COG3041@2|Bacteria,1U616@1239|Firmicutes,4IFQ1@91061|Bacilli,3F6TM@33958|Lactobacillaceae 91061|Bacilli S Bacterial toxin of type II toxin-antitoxin system, YafQ - - - ko:K19157 - - - - ko00000,ko01000,ko02048 - - - YafQ_toxin AGEJAFOK_00274 748671.LCRIS_01464 2.22e-60 186.0 COG0776@1|root,COG0776@2|Bacteria,1U7SQ@1239|Firmicutes,4IHQ6@91061|Bacilli,3FA4D@33958|Lactobacillaceae 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupB2 - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding AGEJAFOK_00275 748671.LCRIS_01465 1.49e-178 498.0 COG1120@1|root,COG1120@2|Bacteria,1V1WZ@1239|Firmicutes,4IPT3@91061|Bacilli 91061|Bacilli HP abc transporter atp-binding protein - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran AGEJAFOK_00276 748671.LCRIS_01466 1.55e-201 560.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4H9QQ@91061|Bacilli,3F4T9@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily isdF - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD AGEJAFOK_00277 748671.LCRIS_01467 2.07e-203 563.0 COG0614@1|root,COG0614@2|Bacteria,1UIJ9@1239|Firmicutes,4HDDF@91061|Bacilli,3F4ZN@33958|Lactobacillaceae 91061|Bacilli P Periplasmic binding protein isdE - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 AGEJAFOK_00278 748671.LCRIS_01468 7.04e-159 446.0 COG5386@1|root,COG5386@2|Bacteria,1VES7@1239|Firmicutes,4HIEC@91061|Bacilli,3F6SK@33958|Lactobacillaceae 91061|Bacilli M Iron Transport-associated domain - - - ko:K14193 ko05150,map05150 - - - ko00000,ko00001 - - - NEAT AGEJAFOK_00280 748671.LCRIS_01470 6.09e-121 347.0 29Q7X@1|root,30B6Y@2|Bacteria,1U7N8@1239|Firmicutes,4IHJH@91061|Bacilli,3F9XW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00281 525365.HMPREF0548_1674 4.53e-11 64.7 2DBU6@1|root,2ZB4C@2|Bacteria,1VNWP@1239|Firmicutes,4HRN6@91061|Bacilli,3F51G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor AGEJAFOK_00282 1423748.BALB01000051_gene2072 1.02e-75 239.0 2DBU6@1|root,2ZB4C@2|Bacteria,1VNWP@1239|Firmicutes,4HRN6@91061|Bacilli,3F51G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor AGEJAFOK_00283 525365.HMPREF0548_1674 2.62e-69 235.0 2DBU6@1|root,2ZB4C@2|Bacteria,1VNWP@1239|Firmicutes,4HRN6@91061|Bacilli,3F51G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor AGEJAFOK_00285 748671.LCRIS_01684 4.4e-165 462.0 COG2461@1|root,COG2461@2|Bacteria,1UI8X@1239|Firmicutes,4ISGE@91061|Bacilli,3FBSZ@33958|Lactobacillaceae 91061|Bacilli S PAS domain - - - - - - - - - - - - PAS_10 AGEJAFOK_00286 748671.LCRIS_00703 1.43e-178 498.0 29XNY@1|root,30JEF@2|Bacteria,1U62I@1239|Firmicutes,4IFRN@91061|Bacilli,3F6VN@33958|Lactobacillaceae 91061|Bacilli S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,SLAP AGEJAFOK_00287 748671.LCRIS_00702 7.65e-101 292.0 COG0789@1|root,COG0789@2|Bacteria,1VDPP@1239|Firmicutes,4HPJY@91061|Bacilli,3F6MS@33958|Lactobacillaceae 91061|Bacilli K MerR HTH family regulatory protein - - - - - - - - - - - - MerR_1 AGEJAFOK_00288 748671.LCRIS_00701 4.36e-27 108.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 AGEJAFOK_00289 748671.LCRIS_00701 5.76e-292 801.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 AGEJAFOK_00290 748671.LCRIS_00700 4.64e-63 196.0 2C9UQ@1|root,32RPZ@2|Bacteria,1VDDQ@1239|Firmicutes,4HNJB@91061|Bacilli,3F5X9@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4811) - - - - - - - - - - - - DUF4811 AGEJAFOK_00292 326425.lhe_1043 0.0 997.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C AGEJAFOK_00293 326425.lhe_1042 1.71e-128 370.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli,3F62J@33958|Lactobacillaceae 91061|Bacilli K UTRA treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA AGEJAFOK_00294 326425.lhe_1041 2.02e-137 407.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system treB - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC AGEJAFOK_00295 575594.ACOH01000002_gene1112 3e-219 620.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system treB - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC AGEJAFOK_00296 748671.LCRIS_01096 1.12e-85 253.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F6HJ@33958|Lactobacillaceae 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC AGEJAFOK_00297 1423748.BALB01000017_gene1468 3.95e-242 672.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F44J@33958|Lactobacillaceae 91061|Bacilli L AAA C-terminal domain - - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N AGEJAFOK_00298 748671.LCRIS_01093 2.71e-16 77.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,3FB44@33958|Lactobacillaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides yqjE - 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 AGEJAFOK_00299 748671.LCRIS_01093 9.42e-267 733.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,3FB44@33958|Lactobacillaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides yqjE - 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 AGEJAFOK_00300 748671.LCRIS_01092 3.45e-109 313.0 COG0454@1|root,COG0456@2|Bacteria,1V2BC@1239|Firmicutes,4IQ27@91061|Bacilli,3FBFB@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10,Acetyltransf_7 AGEJAFOK_00301 748671.LCRIS_01091 2.28e-291 795.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli,3F3QW@33958|Lactobacillaceae 91061|Bacilli S Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_4,YkuD AGEJAFOK_00302 748671.LCRIS_01090 7.89e-124 353.0 COG4720@1|root,COG4720@2|Bacteria,1V52B@1239|Firmicutes,4HKM2@91061|Bacilli,3F4W9@33958|Lactobacillaceae 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS AGEJAFOK_00303 748671.LCRIS_01088 6.55e-129 371.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli,3F3V7@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin AGEJAFOK_00304 748671.LCRIS_01083 9.19e-259 711.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX1 - - - - - - - - - - - Beta-lactamase,SLH AGEJAFOK_00305 748671.LCRIS_01082 1.12e-149 420.0 COG0110@1|root,COG0110@2|Bacteria,1V06U@1239|Firmicutes,4IPZB@91061|Bacilli,3FBEW@33958|Lactobacillaceae 91061|Bacilli S transferase hexapeptide repeat maa3 - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac AGEJAFOK_00306 748671.LCRIS_01081 3.21e-104 301.0 COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,4HH45@91061|Bacilli,3F81Q@33958|Lactobacillaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yvbK - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 AGEJAFOK_00307 748671.LCRIS_01080 1.2e-147 416.0 COG0671@1|root,COG0671@2|Bacteria,1V7XD@1239|Firmicutes,4IPZ9@91061|Bacilli,3FBEV@33958|Lactobacillaceae 91061|Bacilli I Acid phosphatase homologues - - - - - - - - - - - - PAP2 AGEJAFOK_00308 748671.LCRIS_01078 9.17e-241 661.0 COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli,3F4UT@33958|Lactobacillaceae 91061|Bacilli H homocysteine S-methyltransferase mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans AGEJAFOK_00309 748671.LCRIS_01077 0.0 1648.0 COG0178@1|root,COG0178@2|Bacteria,1TP0A@1239|Firmicutes,4HTDZ@91061|Bacilli,3F3V4@33958|Lactobacillaceae 91061|Bacilli L excinuclease ABC, A subunit uvrA2 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - AAA_21,ABC_tran AGEJAFOK_00310 748671.LCRIS_01076 7.27e-106 305.0 COG0716@1|root,COG0716@2|Bacteria,1V465@1239|Firmicutes,4HN5X@91061|Bacilli,3F7H7@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 AGEJAFOK_00311 748671.LCRIS_01075 0.0 1161.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind AGEJAFOK_00312 748671.LCRIS_01074 2.88e-310 844.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,3F3PU@33958|Lactobacillaceae 91061|Bacilli P aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase AGEJAFOK_00313 748671.LCRIS_01073 0.0 1402.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,3F3TV@33958|Lactobacillaceae 91061|Bacilli E Orn/Lys/Arg decarboxylase, C-terminal domain speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.18,4.1.1.19 ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 M00133,M00134 R00462,R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C AGEJAFOK_00314 748671.LCRIS_01072 0.0 980.0 COG0531@1|root,COG0531@2|Bacteria,1UYSD@1239|Firmicutes,4IPMN@91061|Bacilli,3F48U@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 AGEJAFOK_00315 748671.LCRIS_01071 7.88e-121 344.0 COG5015@1|root,COG5015@2|Bacteria,1TR2Q@1239|Firmicutes,4HHXT@91061|Bacilli,3F66T@33958|Lactobacillaceae 91061|Bacilli C Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Fer4,Putative_PNPOx AGEJAFOK_00316 748671.LCRIS_01070 0.0 935.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,3F3UV@33958|Lactobacillaceae 91061|Bacilli E dipeptidase PepV pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 AGEJAFOK_00317 525365.HMPREF0548_1074 3.03e-145 421.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid ybgF - - ko:K02205,ko:K03293,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - - AA_permease AGEJAFOK_00318 405566.lhv_1172 1.31e-16 79.3 COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli,3F4UT@33958|Lactobacillaceae 91061|Bacilli H homocysteine S-methyltransferase mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans AGEJAFOK_00319 748671.LCRIS_01067 2.95e-84 248.0 COG0239@1|root,COG0239@2|Bacteria,1VM30@1239|Firmicutes,4HRC4@91061|Bacilli,3F8A8@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB AGEJAFOK_00320 748671.LCRIS_01066 7.64e-88 258.0 COG0239@1|root,COG0239@2|Bacteria,1U4G6@1239|Firmicutes,4IE88@91061|Bacilli,3F6R4@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB1 - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB AGEJAFOK_00321 748671.LCRIS_01065 2.15e-194 539.0 COG4974@1|root,COG4974@2|Bacteria,1UFH8@1239|Firmicutes,4IES1@91061|Bacilli,3F3KV@33958|Lactobacillaceae 91061|Bacilli L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_1 AGEJAFOK_00322 748671.LCRIS_01997 3.82e-294 805.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease AGEJAFOK_00323 1423767.BALU01000001_gene1593 3.31e-154 435.0 COG0789@1|root,COG0789@2|Bacteria,1V05W@1239|Firmicutes,4HSX6@91061|Bacilli,3F4R7@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 AGEJAFOK_00324 1033837.WANG_1407 1.64e-45 159.0 2DKJE@1|root,309Q1@2|Bacteria,1U5GX@1239|Firmicutes,4IF7Q@91061|Bacilli,3F5X8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_3 AGEJAFOK_00326 97137.C821_01339 4.61e-37 127.0 2C7JY@1|root,2ZYK0@2|Bacteria,1U6US@1239|Firmicutes,4IGNN@91061|Bacilli,3F8IM@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun AGEJAFOK_00329 748671.LCRIS_01792 1.47e-91 268.0 COG3654@1|root,COG3654@2|Bacteria,1VCC8@1239|Firmicutes,4HKXW@91061|Bacilli 91061|Bacilli S Prophage maintenance system killer protein doc - - ko:K07341 - - - - ko00000,ko02048 - - - Fic AGEJAFOK_00330 748671.LCRIS_01791 7.27e-42 137.0 29QEZ@1|root,30BEA@2|Bacteria,1U7ZS@1239|Firmicutes,4IHX6@91061|Bacilli,3FAD5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00331 748671.LCRIS_01789 0.0 1160.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,3F4E5@33958|Lactobacillaceae 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N AGEJAFOK_00332 748671.LCRIS_01788 5.74e-256 706.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr AGEJAFOK_00333 525365.HMPREF0548_1577 2.33e-143 406.0 COG1811@1|root,COG1811@2|Bacteria,1U5PM@1239|Firmicutes,4HEHT@91061|Bacilli,3F56J@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 AGEJAFOK_00334 748671.LCRIS_01786 7.2e-40 136.0 28II2@1|root,2Z8J8@2|Bacteria,1UZV1@1239|Firmicutes,4HV3S@91061|Bacilli,3F960@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00335 748671.LCRIS_01786 5.49e-46 152.0 28II2@1|root,2Z8J8@2|Bacteria,1UZV1@1239|Firmicutes,4HV3S@91061|Bacilli,3F960@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00336 748671.LCRIS_01785 8.69e-93 275.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,3F6YW@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain rimL - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 AGEJAFOK_00337 748671.LCRIS_01784 2.52e-76 228.0 29NYN@1|root,309WR@2|Bacteria,1U5V0@1239|Firmicutes,4IFIN@91061|Bacilli,3F6IV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00338 748671.LCRIS_01783 0.0 1004.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,3FC7X@33958|Lactobacillaceae 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn AGEJAFOK_00339 748671.LCRIS_01782 7.35e-174 486.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE AGEJAFOK_00340 748671.LCRIS_01781 7.36e-109 313.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F63I@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 AGEJAFOK_00341 748671.LCRIS_01780 1.58e-143 405.0 COG4990@1|root,COG4990@2|Bacteria,1V3XE@1239|Firmicutes,4HJBT@91061|Bacilli,3F4HZ@33958|Lactobacillaceae 91061|Bacilli S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 AGEJAFOK_00342 748671.LCRIS_01779 1.16e-101 296.0 29V33@1|root,30GGE@2|Bacteria,1UFZH@1239|Firmicutes,4IF1H@91061|Bacilli,3F5BQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00343 748671.LCRIS_01778 1.96e-226 623.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,3F3P1@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm AGEJAFOK_00344 748671.LCRIS_01777 4.75e-101 293.0 COG1780@1|root,COG1780@2|Bacteria,1V9T1@1239|Firmicutes,4HJ0M@91061|Bacilli,3FBB7@33958|Lactobacillaceae 91061|Bacilli F NrdI Flavodoxin like nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI AGEJAFOK_00345 748671.LCRIS_01776 5.48e-283 772.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F431@33958|Lactobacillaceae 91061|Bacilli L Putative transposase DNA-binding domain tnpB - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon AGEJAFOK_00346 748671.LCRIS_01775 8.77e-144 405.0 29DQI@1|root,300NC@2|Bacteria,1U55V@1239|Firmicutes,4IEX6@91061|Bacilli,3F4UQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00347 748671.LCRIS_01774 0.0 964.0 2EZVI@1|root,33T01@2|Bacteria,1V7RP@1239|Firmicutes,4IEWB@91061|Bacilli,3F4QD@33958|Lactobacillaceae 91061|Bacilli S O-antigen ligase like membrane protein - - - - - - - - - - - - O-antigen_lig AGEJAFOK_00348 748671.LCRIS_01773 3.72e-55 173.0 2DKPT@1|root,30A91@2|Bacteria,1U6CF@1239|Firmicutes,4IG44@91061|Bacilli,3F7KP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2187 AGEJAFOK_00349 748671.LCRIS_01772 4.26e-115 331.0 COG0194@1|root,COG0194@2|Bacteria,1VGNR@1239|Firmicutes,4IRT6@91061|Bacilli,3FBPU@33958|Lactobacillaceae 91061|Bacilli F Guanylate kinase homologues. gmk2 - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin AGEJAFOK_00350 748671.LCRIS_01771 1.47e-114 330.0 COG0791@1|root,COG0791@2|Bacteria,1V5H7@1239|Firmicutes,4IEXC@91061|Bacilli,3F4VI@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 AGEJAFOK_00351 748671.LCRIS_01770 1.28e-174 487.0 COG0791@1|root,COG0791@2|Bacteria,1VG0Z@1239|Firmicutes,4HBE9@91061|Bacilli,3F50V@33958|Lactobacillaceae 91061|Bacilli M NlpC P60 family protein - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 AGEJAFOK_00352 748671.LCRIS_01769 1.73e-167 473.0 COG0791@1|root,COG0791@2|Bacteria,1V5H7@1239|Firmicutes,4HMYU@91061|Bacilli,3FBE5@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 AGEJAFOK_00353 1423758.BN55_08005 3.01e-54 174.0 29P3I@1|root,30A1R@2|Bacteria,1U62V@1239|Firmicutes,4IFS0@91061|Bacilli,3F6WM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00354 748671.LCRIS_01767 1.26e-223 618.0 COG2340@1|root,COG2340@2|Bacteria,1V1IM@1239|Firmicutes,4HRX1@91061|Bacilli,3F43X@33958|Lactobacillaceae 91061|Bacilli S Cysteine-rich secretory protein family - - - - - - - - - - - - Big_2,CAP,SLH AGEJAFOK_00355 748671.LCRIS_01766 7.5e-282 773.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,3F4B2@33958|Lactobacillaceae 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 AGEJAFOK_00358 748671.LCRIS_01762 1.47e-243 670.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr AGEJAFOK_00359 748671.LCRIS_01761 3.05e-184 515.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,3F4M5@33958|Lactobacillaceae 91061|Bacilli M biosynthesis protein epsB - - - - - - - - - - - GNVR,Wzz AGEJAFOK_00360 748671.LCRIS_01760 6.84e-161 453.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,3F4BM@33958|Lactobacillaceae 91061|Bacilli D Capsular exopolysaccharide family ywqD - - - - - - - - - - - AAA_31,ParA AGEJAFOK_00361 748671.LCRIS_01759 6.64e-186 516.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,3F3RT@33958|Lactobacillaceae 91061|Bacilli GM PHP domain protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - AGEJAFOK_00362 748671.LCRIS_01758 1.1e-153 431.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HHDH@91061|Bacilli,3FB5K@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase epsE2 - - - - - - - - - - - Bac_transf AGEJAFOK_00363 525365.HMPREF0548_1604 1.68e-199 560.0 COG0438@1|root,COG0438@2|Bacteria,1UI6T@1239|Firmicutes,4ISFV@91061|Bacilli 91061|Bacilli M Glycosyltransferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 AGEJAFOK_00364 891391.LAC30SC_09370 2.64e-103 298.0 COG0707@1|root,COG0707@2|Bacteria,1V57Q@1239|Firmicutes,4IPPX@91061|Bacilli,3F5GA@33958|Lactobacillaceae 91061|Bacilli M Oligosaccharide biosynthesis protein Alg14 like - - - - - - - - - - - - Alg14 AGEJAFOK_00365 748671.LCRIS_01487 8.08e-117 339.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HFBQ@91061|Bacilli,3F54P@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein cjaA - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 AGEJAFOK_00366 748671.LCRIS_01487 1.02e-67 211.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HFBQ@91061|Bacilli,3F54P@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein cjaA - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 AGEJAFOK_00367 748671.LCRIS_01488 1.89e-171 479.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4HDK7@91061|Bacilli,3FC3P@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran AGEJAFOK_00368 748671.LCRIS_01489 4.11e-150 423.0 COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,4HGVA@91061|Bacilli,3F45E@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnP7 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 AGEJAFOK_00369 748671.LCRIS_01490 1.8e-142 403.0 COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,4HGE1@91061|Bacilli,3F3XD@33958|Lactobacillaceae 91061|Bacilli P ABC transporter, permease protein glnP9 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 AGEJAFOK_00371 1121105.ATXL01000006_gene1366 2.59e-10 63.2 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB AGEJAFOK_00375 748671.LCRIS_00118 3.87e-73 229.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut AGEJAFOK_00376 748671.LCRIS_01061 9.4e-232 635.0 COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,3F3KT@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase lacX - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim AGEJAFOK_00377 575594.ACOH01000002_gene996 9.11e-110 325.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3F3PW@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase - - - - - - - - - - - - Aldo_ket_red AGEJAFOK_00378 748671.LCRIS_01064 9.44e-63 197.0 COG1388@1|root,COG1388@2|Bacteria,1V773@1239|Firmicutes,4HIJG@91061|Bacilli,3F3JQ@33958|Lactobacillaceae 91061|Bacilli M LysM domain protein - - - - - - - - - - - - LysM,SLAP AGEJAFOK_00379 891391.LAC30SC_02550 1.8e-36 129.0 COG1388@1|root,COG1388@2|Bacteria,1V773@1239|Firmicutes,4HIJG@91061|Bacilli,3F3JQ@33958|Lactobacillaceae 91061|Bacilli M LysM domain protein - - - - - - - - - - - - LysM,SLAP AGEJAFOK_00380 748671.LCRIS_00398 2.14e-234 645.0 COG1609@1|root,COG1609@2|Bacteria,1TT9H@1239|Firmicutes,4HDUY@91061|Bacilli,3FC5B@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor scrR - - ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 AGEJAFOK_00381 748671.LCRIS_00399 0.0 1018.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,3F4UD@33958|Lactobacillaceae 91061|Bacilli G invertase scrB - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N AGEJAFOK_00382 748671.LCRIS_00400 0.0 1253.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system scrA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC AGEJAFOK_00383 748671.LCRIS_00401 2.14e-231 637.0 COG0791@1|root,COG0791@2|Bacteria,1VW67@1239|Firmicutes,4HWSY@91061|Bacilli,3F41W@33958|Lactobacillaceae 91061|Bacilli M CHAP domain - - - - - - - - - - - - Amidase_5,Beta-lactamase2,CHAP,NLPC_P60 AGEJAFOK_00384 748671.LCRIS_00402 2.79e-102 298.0 2CHFM@1|root,301I5@2|Bacteria,1U5M7@1239|Firmicutes,4IFC0@91061|Bacilli,3F66G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00385 748671.LCRIS_00403 1.06e-58 181.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,3F7CZ@33958|Lactobacillaceae 91061|Bacilli O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 AGEJAFOK_00386 748671.LCRIS_00404 0.0 1015.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,3F3MM@33958|Lactobacillaceae 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 AGEJAFOK_00387 748671.LCRIS_00405 0.0 1678.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,3F4A5@33958|Lactobacillaceae 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V AGEJAFOK_00388 748671.LCRIS_00406 0.0 1225.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,3F3PK@33958|Lactobacillaceae 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C AGEJAFOK_00389 748671.LCRIS_00407 3.89e-132 375.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,3F42W@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N AGEJAFOK_00390 748671.LCRIS_00408 1.39e-237 654.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,3F47S@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N AGEJAFOK_00391 748671.LCRIS_00409 7.58e-69 210.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,3F7EY@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC AGEJAFOK_00392 748671.LCRIS_00410 0.0 988.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,3F48G@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N AGEJAFOK_00393 748671.LCRIS_00411 6.15e-268 735.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,3F44N@33958|Lactobacillaceae 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH AGEJAFOK_00394 748671.LCRIS_00412 3.16e-231 636.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 AGEJAFOK_00395 748671.LCRIS_00413 1.26e-303 830.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,3F4FQ@33958|Lactobacillaceae 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C AGEJAFOK_00396 748671.LCRIS_00414 0.0 1748.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,3F3QS@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD AGEJAFOK_00397 1423754.BALY01000042_gene1037 5.32e-57 176.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,3F7EG@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 AGEJAFOK_00398 748671.LCRIS_00416 9.37e-96 279.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,3F6NI@33958|Lactobacillaceae 91061|Bacilli J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX AGEJAFOK_00399 748671.LCRIS_00417 1.18e-66 202.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,3F6X3@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 AGEJAFOK_00400 748671.LCRIS_00418 0.0 1359.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,3F4DX@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr AGEJAFOK_00401 748671.LCRIS_00419 5.37e-72 216.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F6Y3@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin AGEJAFOK_00402 748671.LCRIS_00420 2.34e-76 228.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,3F6YZ@33958|Lactobacillaceae 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL AGEJAFOK_00403 748671.LCRIS_00421 5.58e-92 269.0 COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,3F7ZI@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2507) yslB - - - - - - - - - - - DUF2507 AGEJAFOK_00404 748671.LCRIS_00422 1.68e-185 516.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,3F446@33958|Lactobacillaceae 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race AGEJAFOK_00405 748671.LCRIS_00423 8.12e-144 405.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,3F3KD@33958|Lactobacillaceae 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like AGEJAFOK_00406 891391.LAC30SC_08770 1.55e-29 118.0 29NJE@1|root,3021E@2|Bacteria,1U628@1239|Firmicutes,4IFR8@91061|Bacilli,3F6V0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_3 AGEJAFOK_00407 1293597.BN147_01990 2.86e-169 488.0 COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,4H9WS@91061|Bacilli,3FBX3@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66 AGEJAFOK_00409 1423754.BALY01000062_gene1839 3.31e-65 199.0 COG3436@1|root,COG3436@2|Bacteria,1VAJD@1239|Firmicutes,4HKCG@91061|Bacilli,3F7E1@33958|Lactobacillaceae 91061|Bacilli L PFAM IS66 Orf2 family protein XK27_01125 - - ko:K07484 - - - - ko00000 - - - TnpB_IS66 AGEJAFOK_00411 1423814.HMPREF0549_0518 7.88e-59 193.0 COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,4IPIE@91061|Bacilli,3FBCX@33958|Lactobacillaceae 91061|Bacilli L Transposase, IS116 IS110 IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 AGEJAFOK_00412 575594.ACOH01000003_gene849 2.48e-147 452.0 COG0810@1|root,COG0810@2|Bacteria,1UIXM@1239|Firmicutes,4ISVX@91061|Bacilli,3F5J8@33958|Lactobacillaceae 91061|Bacilli M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins aapA - - - - - - - - - - - Gram_pos_anchor,MucBP,YSIRK_signal AGEJAFOK_00413 748671.LCRIS_01389 2.44e-285 780.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase AGEJAFOK_00414 748671.LCRIS_01391 0.0 954.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HA0N@91061|Bacilli,3F4J0@33958|Lactobacillaceae 91061|Bacilli E Amino Acid potE - - - - - - - - - - - AA_permease_2 AGEJAFOK_00415 748671.LCRIS_01393 2.65e-107 315.0 COG3177@1|root,COG3177@2|Bacteria,1V3AX@1239|Firmicutes,4HVK3@91061|Bacilli,3F4YX@33958|Lactobacillaceae 91061|Bacilli S Fic/DOC family - - - - - - - - - - - - Fic AGEJAFOK_00416 748671.LCRIS_01394 0.0 963.0 2FIUN@1|root,34AK2@2|Bacteria,1W1FZ@1239|Firmicutes,4HYXZ@91061|Bacilli,3F4EU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Big_3,SH3_8 AGEJAFOK_00417 748671.LCRIS_01395 5.87e-110 323.0 29NM6@1|root,309J4@2|Bacteria,1U575@1239|Firmicutes,4IEYP@91061|Bacilli,3F507@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00418 748671.LCRIS_01396 1.92e-113 326.0 COG3152@1|root,COG3152@2|Bacteria,1VDSW@1239|Firmicutes,4HMMJ@91061|Bacilli,3F4C0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF805) yhaH - - - - - - - - - - - DUF805 AGEJAFOK_00419 748671.LCRIS_01397 2.65e-89 262.0 COG1765@1|root,COG1765@2|Bacteria,1VN90@1239|Firmicutes,4HRIC@91061|Bacilli,3F6MQ@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC AGEJAFOK_00420 748671.LCRIS_01398 1.36e-266 731.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HX8J@91061|Bacilli,3F43Q@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 AGEJAFOK_00421 748671.LCRIS_01399 3e-290 794.0 COG0642@1|root,COG0642@2|Bacteria,1UHQH@1239|Firmicutes,4HAHG@91061|Bacilli,3F4JY@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase sptS - - - - - - - - - - - HATPase_c,HisKA AGEJAFOK_00422 748671.LCRIS_01818 5.97e-177 496.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve AGEJAFOK_00423 748671.LCRIS_00145 2.34e-40 143.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve AGEJAFOK_00424 748671.LCRIS_01408 6.89e-93 279.0 COG1609@1|root,COG1609@2|Bacteria,1UVZE@1239|Firmicutes,4I2X3@91061|Bacilli,3F6DT@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding protein domain - - - ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_4 AGEJAFOK_00425 748671.LCRIS_01409 2.14e-48 154.0 2DTY5@1|root,33N6A@2|Bacteria,1W48A@1239|Firmicutes,4I01I@91061|Bacilli,3F7WG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00426 748671.LCRIS_01410 1.6e-251 688.0 COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,4HADZ@91061|Bacilli,3F48R@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim AGEJAFOK_00427 748671.LCRIS_01411 0.0 996.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli,3F4D8@33958|Lactobacillaceae 91061|Bacilli G UDP-glucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf AGEJAFOK_00428 748671.LCRIS_01412 3.56e-281 768.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli,3F3Q9@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg AGEJAFOK_00429 748671.LCRIS_01413 0.0 1186.0 COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4HARI@91061|Bacilli,3F3PC@33958|Lactobacillaceae 91061|Bacilli G -beta-galactosidase lacZ - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M AGEJAFOK_00430 1033837.WANG_0295 0.0 1082.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli,3F3P7@33958|Lactobacillaceae 91061|Bacilli G Transporter lacS - - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 AGEJAFOK_00431 525365.HMPREF0548_0296 1.48e-210 585.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator lacR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 AGEJAFOK_00432 525365.HMPREF0548_0297 0.0 1101.0 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HANW@91061|Bacilli,3F4EI@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 2 family lacL - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N AGEJAFOK_00433 525365.HMPREF0548_0298 4.35e-185 519.0 COG3250@1|root,COG3250@2|Bacteria,1TRVA@1239|Firmicutes,4HFMH@91061|Bacilli,3F51Z@33958|Lactobacillaceae 91061|Bacilli G beta-galactosidase lacM - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N AGEJAFOK_00434 748671.LCRIS_01418 2.84e-240 660.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd AGEJAFOK_00435 748671.LCRIS_01419 2.44e-210 581.0 COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,4HGAF@91061|Bacilli,3F4R3@33958|Lactobacillaceae 91061|Bacilli S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii AGEJAFOK_00436 748671.LCRIS_01420 5.55e-137 387.0 COG5340@1|root,COG5340@2|Bacteria,1V3JU@1239|Firmicutes,4HMVW@91061|Bacilli,3F608@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, AbiEi antitoxin - - - - - - - - - - - - AbiEi_4 AGEJAFOK_00437 748671.LCRIS_01421 4.05e-242 665.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HEN1@91061|Bacilli,3FC5D@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding protein-like domain - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 AGEJAFOK_00438 891391.LAC30SC_01400 9.45e-287 788.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,3FCFA@33958|Lactobacillaceae 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 AGEJAFOK_00441 575594.ACOH01000006_gene301 1.1e-96 290.0 COG1277@1|root,COG1277@2|Bacteria,1V1GX@1239|Firmicutes,4HG2P@91061|Bacilli,3F52P@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_4 AGEJAFOK_00442 575594.ACOH01000006_gene300 4.03e-75 235.0 COG1277@1|root,COG1277@2|Bacteria,1V1GX@1239|Firmicutes,4HG2P@91061|Bacilli,3F52P@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_4 AGEJAFOK_00443 1423814.HMPREF0549_1150 8.34e-116 342.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,3F3YW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AGEJAFOK_00444 1423747.BAMJ01000028_gene1724 8.77e-189 538.0 COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,4HBQW@91061|Bacilli,3F535@33958|Lactobacillaceae 91061|Bacilli S Metal-independent alpha-mannosidase (GH125) - - - ko:K09704 - - - - ko00000 - - - Glyco_hydro_125 AGEJAFOK_00445 748671.LCRIS_00749 1.91e-233 642.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,3F40I@33958|Lactobacillaceae 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI AGEJAFOK_00446 908339.HMPREF9265_1537 6.61e-186 528.0 COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae 91061|Bacilli S cog cog1373 - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 AGEJAFOK_00447 748671.LCRIS_00558 0.0 1194.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,3F3QX@33958|Lactobacillaceae 91061|Bacilli S Myosin-crossreactive antigen - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA AGEJAFOK_00448 748671.LCRIS_00557 1.52e-119 341.0 COG1309@1|root,COG1309@2|Bacteria,1VM8R@1239|Firmicutes,4HRXE@91061|Bacilli,3F63U@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N AGEJAFOK_00449 748671.LCRIS_00556 0.0 908.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator qacA - - - - - - - - - - - MFS_1 AGEJAFOK_00454 748671.LCRIS_00554 1.42e-122 348.0 COG0454@1|root,COG0456@2|Bacteria,1VJPU@1239|Firmicutes,4HG6J@91061|Bacilli,3F5MH@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 AGEJAFOK_00455 748671.LCRIS_00553 0.0 875.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F41R@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_2 - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr AGEJAFOK_00456 748671.LCRIS_00552 1.01e-256 702.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase flp - - - - - - - - - - - Beta-lactamase,SLH AGEJAFOK_00457 748671.LCRIS_00551 2.79e-309 845.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,3F3VX@33958|Lactobacillaceae 91061|Bacilli C Na H antiporter NhaC nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter AGEJAFOK_00458 1423758.BN55_03550 9.92e-187 526.0 COG1835@1|root,COG1835@2|Bacteria,1V7GP@1239|Firmicutes,4HJ4R@91061|Bacilli,3F42R@33958|Lactobacillaceae 91061|Bacilli I transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - Acyl_transf_3 AGEJAFOK_00459 748671.LCRIS_00548 1.46e-75 226.0 2BQGU@1|root,32JC9@2|Bacteria,1UQJZ@1239|Firmicutes,4IFJT@91061|Bacilli,3F6M4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00460 748671.LCRIS_00534 2.61e-148 419.0 COG0670@1|root,COG0670@2|Bacteria,1V779@1239|Firmicutes,4HIX1@91061|Bacilli,3F3QH@33958|Lactobacillaceae 91061|Bacilli S Belongs to the BI1 family ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I AGEJAFOK_00461 748671.LCRIS_00533 5.58e-219 604.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,3F447@33958|Lactobacillaceae 91061|Bacilli G Lipid kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat AGEJAFOK_00462 748671.LCRIS_00532 0.0 951.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,3F44H@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey AGEJAFOK_00463 748671.LCRIS_00531 0.0 928.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,3F4BK@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase AGEJAFOK_00464 748671.LCRIS_00530 5.42e-67 203.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,3F7XB@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln AGEJAFOK_00465 748671.LCRIS_00529 6.25e-268 734.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,3F3KI@33958|Lactobacillaceae 91061|Bacilli S sex pheromone camS - - - - - - - - - - - CamS AGEJAFOK_00466 748671.LCRIS_00528 0.0 1302.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,3F43C@33958|Lactobacillaceae 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 AGEJAFOK_00467 748671.LCRIS_00527 0.0 1457.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C AGEJAFOK_00468 748671.LCRIS_00526 2.26e-118 342.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli,3F584@33958|Lactobacillaceae 91061|Bacilli NU mannosyl-glycoprotein acmA - 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,SH3_8,YceG AGEJAFOK_00470 748671.LCRIS_00525 2.62e-109 314.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,3F703@33958|Lactobacillaceae 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT AGEJAFOK_00471 748671.LCRIS_00524 5.48e-173 481.0 COG3774@1|root,COG3774@2|Bacteria,1V9J7@1239|Firmicutes,4HIAM@91061|Bacilli,3F4U2@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase sugar-binding region containing DXD motif - - - - - - - - - - - - Caps_synth,Gly_transf_sug AGEJAFOK_00472 748671.LCRIS_00523 0.0 896.0 COG2244@1|root,COG2244@2|Bacteria,1TRTX@1239|Firmicutes,4HDWM@91061|Bacilli,3FB7P@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein epsU - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C AGEJAFOK_00473 748671.LCRIS_00522 9.16e-287 782.0 COG1887@1|root,COG1887@2|Bacteria,1VD8C@1239|Firmicutes,4HI8C@91061|Bacilli,3F52X@33958|Lactobacillaceae 91061|Bacilli M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - - - - - - - - - - Glyphos_transf AGEJAFOK_00474 748671.LCRIS_00521 0.0 1157.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase AGEJAFOK_00475 891391.LAC30SC_07290 3.35e-55 188.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 AGEJAFOK_00476 326425.lhe_1310 3.74e-182 511.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HDIR@91061|Bacilli,3FCB7@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component oppC5 - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N AGEJAFOK_00477 891391.LAC30SC_07300 7.92e-221 610.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,3FCCU@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease oppB - - ko:K02033,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 AGEJAFOK_00478 525365.HMPREF0548_0846 3.27e-229 632.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,3F4GM@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY AGEJAFOK_00479 748671.LCRIS_01315 1.21e-245 674.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY AGEJAFOK_00480 748671.LCRIS_01316 7.32e-46 148.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,3F7F4@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding AGEJAFOK_00481 748671.LCRIS_01317 3.69e-233 642.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,3F4N9@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis AGEJAFOK_00482 748671.LCRIS_01318 0.0 1301.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,3F3JW@33958|Lactobacillaceae 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge AGEJAFOK_00483 748671.LCRIS_01319 0.0 1054.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,3F3X0@33958|Lactobacillaceae 91061|Bacilli S DAK2 domain fusion protein YloV yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 AGEJAFOK_00484 748671.LCRIS_01320 8.29e-75 224.0 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,3F72W@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function yloU - - - - - - - - - - - Asp23 AGEJAFOK_00485 1423767.BALU01000005_gene935 1.33e-35 120.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli,3F7ZN@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 AGEJAFOK_00486 139871.Q9AZ81_9VIRU 1.13e-115 341.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - AGEJAFOK_00487 257314.LJ_1419 5.77e-39 134.0 29QD3@1|root,30BCB@2|Bacteria,1U7WG@1239|Firmicutes,4IHTV@91061|Bacilli,3FA9C@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage holin of superfamily 6 (Holin_LLH) - - - - - - - - - - - - Phage_holin_6_1 AGEJAFOK_00495 1423767.BALU01000006_gene762 1.61e-155 504.0 COG4926@1|root,COG4926@2|Bacteria,1UVZB@1239|Firmicutes,4I2D0@91061|Bacilli,3F5KN@33958|Lactobacillaceae 91061|Bacilli S Phage minor structural protein - - - - - - - - - - - - Prophage_tail AGEJAFOK_00497 1545701.LACWKB10_1193 7.57e-134 469.0 COG0791@1|root,COG3064@1|root,COG3953@1|root,COG5283@1|root,COG5412@1|root,COG0791@2|Bacteria,COG3064@2|Bacteria,COG3953@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,1UZN8@1239|Firmicutes,4HGQG@91061|Bacilli,3F3T2@33958|Lactobacillaceae 91061|Bacilli L Phage tail tape measure protein TP901 - - - - - - - - - - - - NLPC_P60,Peptidase_M23,PhageMin_Tail,SLT AGEJAFOK_00505 797515.HMPREF9103_02439 6.39e-66 223.0 COG4653@1|root,COG4653@2|Bacteria,1UACS@1239|Firmicutes,4HEAS@91061|Bacilli,3FB8A@33958|Lactobacillaceae 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid AGEJAFOK_00506 1423758.BN55_04260 2.93e-108 318.0 COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,4HBZH@91061|Bacilli,3F5E9@33958|Lactobacillaceae 91061|Bacilli OU Belongs to the peptidase S14 family - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease AGEJAFOK_00507 1423758.BN55_04255 3.53e-168 481.0 COG4695@1|root,COG4695@2|Bacteria,1UY1R@1239|Firmicutes,4HDQZ@91061|Bacilli,3FB4M@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal AGEJAFOK_00509 1423758.BN55_04245 0.0 965.0 COG4626@1|root,COG4626@2|Bacteria,1TR5W@1239|Firmicutes,4HEDC@91061|Bacilli,3FB4K@33958|Lactobacillaceae 91061|Bacilli S Phage Terminase - - - - - - - - - - - - Terminase_1 AGEJAFOK_00512 12417.Q9T1G0_9CAUD 1.21e-74 226.0 4QBS6@10239|Viruses,4QUNW@35237|dsDNA viruses no RNA stage,4QPP2@28883|Caudovirales,4QM0S@10699|Siphoviridae 10699|Siphoviridae S Phage terminase, small subunit - - - - - - - - - - - - - AGEJAFOK_00513 1423758.BN55_04235 1.34e-62 198.0 COG1403@1|root,COG1403@2|Bacteria,1VQIP@1239|Firmicutes,4HM74@91061|Bacilli,3F6KP@33958|Lactobacillaceae 91061|Bacilli L HNH nucleases - - - - - - - - - - - - AAA_33,HNH AGEJAFOK_00518 349123.Lreu23DRAFT_4223 3.85e-49 159.0 2DJ23@1|root,32UC6@2|Bacteria,1VA3C@1239|Firmicutes,4HPYG@91061|Bacilli,3F7VB@33958|Lactobacillaceae 91061|Bacilli S VRR_NUC - - - - - - - - - - - - VRR_NUC AGEJAFOK_00529 1423814.HMPREF0549_0148 0.0 926.0 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,3F3UD@33958|Lactobacillaceae 91061|Bacilli S Phage plasmid primase, P4 - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol AGEJAFOK_00530 1423743.JCM14108_2657 1.41e-23 99.8 2CTNW@1|root,32STT@2|Bacteria,1VATD@1239|Firmicutes,4HPYZ@91061|Bacilli,3F56X@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF669) - - - - - - - - - - - - DUF669 AGEJAFOK_00531 334390.LAF_0464 1.07e-182 524.0 COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein - - - - - - - - - - - - Helicase_C,ResIII AGEJAFOK_00533 1293597.BN147_08805 8.83e-88 266.0 28P42@1|root,2ZBZC@2|Bacteria,1V2PN@1239|Firmicutes,4HFRP@91061|Bacilli,3F4QE@33958|Lactobacillaceae 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_24 AGEJAFOK_00539 891391.LAC30SC_06675 5.99e-61 187.0 2DKNQ@1|root,30A2R@2|Bacteria,1U641@1239|Firmicutes,4IFTI@91061|Bacilli,3F6ZG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00540 1293597.BN147_08455 1.23e-101 303.0 COG3645@1|root,COG3646@1|root,COG3645@2|Bacteria,COG3646@2|Bacteria,1UJ7Y@1239|Firmicutes,4HEJY@91061|Bacilli 91061|Bacilli S Phage antirepressor protein KilAC domain - - - - - - - - - - - - ANT,Phage_pRha AGEJAFOK_00541 349123.Lreu23DRAFT_4238 2.69e-25 95.5 COG1396@1|root,COG1396@2|Bacteria,1VMFQ@1239|Firmicutes,4HSBC@91061|Bacilli,3F95W@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_26 AGEJAFOK_00542 655812.HMPREF0061_0221 2.15e-09 58.2 COG1396@1|root,COG1396@2|Bacteria,1UW3K@1239|Firmicutes,4I3YP@91061|Bacilli,27F1T@186827|Aerococcaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - - AGEJAFOK_00545 326425.lhe_1242 8.76e-146 425.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family int3 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase AGEJAFOK_00546 525365.HMPREF0548_0838 2.29e-41 137.0 2AE84@1|root,31424@2|Bacteria,1U65W@1239|Firmicutes,4IFVX@91061|Bacilli,3F756@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00547 748671.LCRIS_01325 1.1e-159 447.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,3F4N8@33958|Lactobacillaceae 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic AGEJAFOK_00548 748671.LCRIS_01326 7.49e-154 432.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3F4KX@33958|Lactobacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim AGEJAFOK_00549 748671.LCRIS_01327 1.71e-208 577.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,3F3XH@33958|Lactobacillaceae 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N AGEJAFOK_00550 748671.LCRIS_01328 0.0 1239.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase AGEJAFOK_00551 748671.LCRIS_01329 3.28e-179 499.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,3F4UI@33958|Lactobacillaceae 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 AGEJAFOK_00552 748671.LCRIS_01330 7.82e-311 848.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,3F45F@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB AGEJAFOK_00553 748671.LCRIS_01331 1.27e-219 606.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,3F4N7@33958|Lactobacillaceae 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N AGEJAFOK_00554 748671.LCRIS_01332 0.0 1566.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,3F3N8@33958|Lactobacillaceae 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII AGEJAFOK_00555 272621.LBA1324 2.37e-46 149.0 COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,3F81N@33958|Lactobacillaceae 91061|Bacilli K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 AGEJAFOK_00556 748671.LCRIS_01334 5.97e-145 408.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,3F3X9@33958|Lactobacillaceae 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin AGEJAFOK_00557 748671.LCRIS_01335 2.19e-100 291.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,3F7EV@33958|Lactobacillaceae 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH AGEJAFOK_00558 748671.LCRIS_01336 0.0 1055.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,3F43U@33958|Lactobacillaceae 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N AGEJAFOK_00559 748671.LCRIS_01337 7.22e-197 545.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,3F45T@33958|Lactobacillaceae 91061|Bacilli J Ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 AGEJAFOK_00560 748671.LCRIS_01338 6.44e-205 567.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,3F436@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt AGEJAFOK_00561 748671.LCRIS_01339 1.53e-47 152.0 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,3F81K@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S AGEJAFOK_00562 748671.LCRIS_01340 1.97e-248 691.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,3F4RE@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 AGEJAFOK_00563 748671.LCRIS_01341 7.19e-199 551.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,3F46A@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C AGEJAFOK_00564 748671.LCRIS_01342 2.78e-85 251.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,3F7KW@33958|Lactobacillaceae 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB AGEJAFOK_00565 748671.LCRIS_01343 7.98e-93 271.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,3F71X@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 AGEJAFOK_00566 748671.LCRIS_01344 2.11e-133 378.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F422@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C AGEJAFOK_00567 748671.LCRIS_01345 1.75e-256 704.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,3F4DR@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 AGEJAFOK_00568 748671.LCRIS_01346 7.95e-64 194.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,3F6WU@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 AGEJAFOK_00569 1423748.BALB01000011_gene1170 6.82e-66 200.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,3F6WT@33958|Lactobacillaceae 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p AGEJAFOK_00570 748671.LCRIS_01348 5.24e-194 538.0 COG1284@1|root,COG1284@2|Bacteria,1TWZ5@1239|Firmicutes,4HD8R@91061|Bacilli,3F54A@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - DUF2179,YitT_membrane AGEJAFOK_00571 748671.LCRIS_01349 0.0 879.0 2EM25@1|root,33ERN@2|Bacteria,1VK4A@1239|Firmicutes,4HRGD@91061|Bacilli,3F53P@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2325) - - - - - - - - - - - - DUF2325 AGEJAFOK_00573 748671.LCRIS_01351 2.07e-38 127.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,3F83T@33958|Lactobacillaceae 91061|Bacilli G Belongs to the 4-oxalocrotonate tautomerase family dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase AGEJAFOK_00574 748671.LCRIS_01352 0.0 1030.0 COG4907@1|root,COG4907@2|Bacteria,1TS3Q@1239|Firmicutes,4HF7D@91061|Bacilli,3F4AT@33958|Lactobacillaceae 91061|Bacilli S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 AGEJAFOK_00575 748671.LCRIS_01353 8.21e-200 555.0 COG1073@1|root,COG1073@2|Bacteria,1V3U9@1239|Firmicutes,4HKRG@91061|Bacilli,3F5VU@33958|Lactobacillaceae 91061|Bacilli S Serine hydrolase (FSH1) cinI - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Abhydrolase_4,Hydrolase_4 AGEJAFOK_00576 748671.LCRIS_01354 4.73e-269 739.0 COG3757@1|root,COG3757@2|Bacteria,1VF8D@1239|Firmicutes,4HX0U@91061|Bacilli,3F4U9@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,LysM,SH3_5,SLAP AGEJAFOK_00578 748671.LCRIS_01355 1.23e-227 625.0 COG0657@1|root,COG0657@2|Bacteria,1V2AW@1239|Firmicutes,4HU2V@91061|Bacilli,3F3N7@33958|Lactobacillaceae 91061|Bacilli I Carboxylesterase family lipA - - - - - - - - - - - Abhydrolase_3 AGEJAFOK_00579 748671.LCRIS_01356 1.82e-86 253.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,3F72U@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin AGEJAFOK_00580 748671.LCRIS_01357 0.0 981.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F46B@33958|Lactobacillaceae 91061|Bacilli V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran AGEJAFOK_00581 748671.LCRIS_01358 0.0 1001.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F46B@33958|Lactobacillaceae 91061|Bacilli V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran AGEJAFOK_00582 748671.LCRIS_01359 1.13e-155 439.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3F3YK@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase supH - - - - - - - - - - - Hydrolase_3 AGEJAFOK_00585 326425.lhe_1187 8.77e-220 612.0 COG3757@1|root,COG3757@2|Bacteria,1U5RB@1239|Firmicutes,4IFFD@91061|Bacilli,3F6D0@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25 AGEJAFOK_00586 97137.C821_00020 2.16e-39 135.0 2C82D@1|root,2ZXDJ@2|Bacteria,1U8KB@1239|Firmicutes,4IIIA@91061|Bacilli,3FB2T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00587 97137.C821_00021 6.31e-27 100.0 29QIP@1|root,30BI6@2|Bacteria,1U85P@1239|Firmicutes,4II37@91061|Bacilli,3FAJW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00590 97137.C821_00024 1.75e-26 97.8 29QHR@1|root,30BH7@2|Bacteria,1U84B@1239|Firmicutes,4II1S@91061|Bacilli,3FAIF@33958|Lactobacillaceae 91061|Bacilli S Phage uncharacterised protein (Phage_XkdX) - - - - - - - - - - - - Phage_XkdX AGEJAFOK_00591 97137.C821_00025 4.37e-38 137.0 29PVG@1|root,30ATQ@2|Bacteria,1U73C@1239|Firmicutes,4IGXY@91061|Bacilli,3F8XC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00599 1545701.LACWKB10_1199 3.57e-141 414.0 COG3299@1|root,COG3299@2|Bacteria,1TQXP@1239|Firmicutes,4H9W7@91061|Bacilli,3F63V@33958|Lactobacillaceae 91061|Bacilli S Baseplate J-like protein - - - - - - - - - - - - Baseplate_J AGEJAFOK_00600 97137.C821_00035 1.55e-40 138.0 29PRA@1|root,30API@2|Bacteria,1U6Y7@1239|Firmicutes,4IGSD@91061|Bacilli,3F8PX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00601 97137.C821_00036 1.66e-48 160.0 2C82E@1|root,30687@2|Bacteria,1TZCA@1239|Firmicutes,4IGX0@91061|Bacilli,3F8W6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00602 97137.C821_00037 2.15e-126 374.0 2D9AP@1|root,32TSY@2|Bacteria,1VDJB@1239|Firmicutes,4HEQ7@91061|Bacilli,3F5N8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00603 1545701.LACWKB10_1195 1.62e-59 187.0 2DNNQ@1|root,32YB6@2|Bacteria,1VG3W@1239|Firmicutes,4HNN6@91061|Bacilli,3F8ZB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00604 1545701.LACWKB10_1194 4.24e-53 184.0 COG1388@1|root,COG1388@2|Bacteria,1U6TX@1239|Firmicutes,4IGMR@91061|Bacilli,3F8HC@33958|Lactobacillaceae 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM AGEJAFOK_00605 525318.HMPREF0497_1637 1.13e-236 751.0 COG0791@1|root,COG1196@1|root,COG5283@1|root,COG5412@1|root,COG0791@2|Bacteria,COG1196@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,1UZN8@1239|Firmicutes,4HGQG@91061|Bacilli,3F3T2@33958|Lactobacillaceae 91061|Bacilli L Phage tail tape measure protein TP901 - - - - - - - - - - - - NLPC_P60,PhageMin_Tail,SLT AGEJAFOK_00608 97137.C821_00044 1.2e-167 481.0 2DBB8@1|root,2Z867@2|Bacteria,1TS0I@1239|Firmicutes,4HERB@91061|Bacilli,3F68G@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3383) - - - - - - - - - - - - DUF3383 AGEJAFOK_00611 148814.JI66_07025 6.61e-24 100.0 2BMXP@1|root,32GHE@2|Bacteria,1V8VX@1239|Firmicutes,4HMRA@91061|Bacilli,3F8DN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00612 97137.C821_00048 2.36e-37 130.0 29QAX@1|root,30BA5@2|Bacteria,1U7T1@1239|Firmicutes,4IHQG@91061|Bacilli,3FA4U@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF4054) - - - - - - - - - - - - DUF4054 AGEJAFOK_00614 1545701.LACWKB10_1183 8.98e-25 102.0 29PRT@1|root,30AQ0@2|Bacteria,1U6YU@1239|Firmicutes,4IGT1@91061|Bacilli,3F8QV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00615 97137.C821_00051 5.02e-70 231.0 COG3566@1|root,COG3566@2|Bacteria,1UZFE@1239|Firmicutes,4HDHG@91061|Bacilli,3F6B0@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2213) - - - ko:K09960 - - - - ko00000 - - - DUF2213 AGEJAFOK_00616 1545701.LACWKB10_1181 2.36e-27 104.0 29QEA@1|root,30BDM@2|Bacteria,1U7YR@1239|Firmicutes,4IHW5@91061|Bacilli,3FAC0@33958|Lactobacillaceae 91061|Bacilli S Lysin motif - - - - - - - - - - - - LysM AGEJAFOK_00617 97137.C821_00053 5.57e-69 221.0 COG2369@1|root,COG2369@2|Bacteria,1V5V6@1239|Firmicutes,4HIDN@91061|Bacilli,3F7F8@33958|Lactobacillaceae 91061|Bacilli S Phage Mu protein F like protein - - - - - - - - - - - - ADPrib_exo_Tox,Phage_Mu_F AGEJAFOK_00618 1545701.LACWKB10_1179 1.16e-110 342.0 COG3567@1|root,COG3567@2|Bacteria,1TQTY@1239|Firmicutes,4HCFU@91061|Bacilli,3F6UA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1073) - - - ko:K09961 - - - - ko00000 - - - DUF1073 AGEJAFOK_00619 97137.C821_00055 4.27e-234 657.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli,3F5CJ@33958|Lactobacillaceae 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C AGEJAFOK_00622 1416334.X2CXX2_9CAUD 9.77e-27 103.0 4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QII1@10662|Myoviridae 10662|Myoviridae S N-methyltransferase activity - - - - - - - - - - - - - AGEJAFOK_00630 891391.LAC30SC_06595 3.69e-15 70.5 2E3FM@1|root,32YEF@2|Bacteria,1VF4E@1239|Firmicutes,4IRKE@91061|Bacilli,3FBPE@33958|Lactobacillaceae 91061|Bacilli S VRR_NUC - - - - - - - - - - - - VRR_NUC AGEJAFOK_00632 97137.C821_00091 7.58e-90 271.0 COG3646@1|root,COG3646@2|Bacteria,1V7KA@1239|Firmicutes,4HK0P@91061|Bacilli,3F7GZ@33958|Lactobacillaceae 91061|Bacilli S ORF6C domain - - - - - - - - - - - - ORF6C,ORF6N,Phage_pRha AGEJAFOK_00637 205914.HS_0144 5.95e-24 101.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1Y7TH@135625|Pasteurellales 135625|Pasteurellales E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC AGEJAFOK_00639 1423767.BALU01000006_gene800 2.8e-38 140.0 COG1846@1|root,COG1846@2|Bacteria,1UPK8@1239|Firmicutes,4IV6I@91061|Bacilli,3F8S8@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_36 AGEJAFOK_00640 324831.LGAS_0582 4.86e-54 184.0 2DKJG@1|root,309QB@2|Bacteria,1U5HA@1239|Firmicutes,4IF84@91061|Bacilli,3F5Y7@33958|Lactobacillaceae 91061|Bacilli S ERF superfamily - - - - - - - - - - - - ERF AGEJAFOK_00641 891391.LAC30SC_06650 4.51e-65 213.0 2EHDI@1|root,33B5D@2|Bacteria,1VPW3@1239|Firmicutes,4HXEN@91061|Bacilli,3F6I3@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1351) - - - - - - - - - - - - DUF1351 AGEJAFOK_00648 1423767.BALU01000006_gene808 6.19e-16 72.4 2DKSW@1|root,30APK@2|Bacteria,1U6Y9@1239|Firmicutes,4IGSF@91061|Bacilli,3F8Q3@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 AGEJAFOK_00649 139871.A9D9J6_9VIRU 7.75e-24 95.1 4QAQV@10239|Viruses 10239|Viruses S protein disulfide oxidoreductase activity - - - - - - - - - - - - - AGEJAFOK_00651 97137.C821_00095 3.93e-05 51.2 2BE7U@1|root,327YU@2|Bacteria,1U6W6@1239|Firmicutes,4IGQB@91061|Bacilli,3F8KV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00652 1423767.BALU01000006_gene814 2.73e-112 340.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase AGEJAFOK_00653 748671.LCRIS_01359 2.93e-16 76.6 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3F3YK@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase supH - - - - - - - - - - - Hydrolase_3 AGEJAFOK_00654 748671.LCRIS_01360 4.3e-66 201.0 29I74@1|root,30548@2|Bacteria,1TXP0@1239|Firmicutes,4I6PG@91061|Bacilli,3F7AE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00655 748671.LCRIS_01361 8.51e-50 158.0 2DKR3@1|root,30AEW@2|Bacteria,1U6JT@1239|Firmicutes,4IGCA@91061|Bacilli,3F81U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00656 1423754.BALY01000006_gene1349 2.48e-80 246.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 AGEJAFOK_00657 1423754.BALY01000006_gene1349 6.78e-24 97.4 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 AGEJAFOK_00658 1423767.BALU01000005_gene884 0.0 1509.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4IRQ0@91061|Bacilli,3FCF2@33958|Lactobacillaceae 91061|Bacilli E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 AGEJAFOK_00659 748671.LCRIS_01365 2.88e-105 303.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,3F6H4@33958|Lactobacillaceae 91061|Bacilli O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR AGEJAFOK_00660 748671.LCRIS_01366 8.74e-62 189.0 2DKNK@1|root,30A2I@2|Bacteria,1U63R@1239|Firmicutes,4IFT6@91061|Bacilli,3F6YT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00661 748671.LCRIS_01367 6.79e-190 529.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport - - - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport AGEJAFOK_00662 748671.LCRIS_01368 0.0 911.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,3F4EG@33958|Lactobacillaceae 91061|Bacilli C L-lactate permease lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm AGEJAFOK_00663 748671.LCRIS_01369 0.0 2085.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS AGEJAFOK_00664 748671.LCRIS_01370 4.22e-269 735.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase AGEJAFOK_00665 748671.LCRIS_01371 8.31e-313 851.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,3F3S3@33958|Lactobacillaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 AGEJAFOK_00666 748671.LCRIS_01372 3.68e-230 633.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,3F4BQ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N AGEJAFOK_00667 748671.LCRIS_01373 2.9e-122 349.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,3F4SR@33958|Lactobacillaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran AGEJAFOK_00668 748671.LCRIS_01374 8.81e-212 586.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,3F4PJ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh AGEJAFOK_00669 748671.LCRIS_01375 1.56e-164 460.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,3F47Y@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase AGEJAFOK_00670 748671.LCRIS_01376 5.5e-154 432.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,3F487@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran AGEJAFOK_00671 272621.LBA1388 4.37e-132 377.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HCVT@91061|Bacilli,3F4ZZ@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 AGEJAFOK_00673 698737.SLGD_00019 1.28e-162 472.0 COG1944@1|root,COG1944@2|Bacteria,1VP3X@1239|Firmicutes,4IRGK@91061|Bacilli 91061|Bacilli S YcaO cyclodehydratase, ATP-ad Mg2+-binding sagD - - - - - - - - - - - YcaO AGEJAFOK_00675 324831.LGAS_0993 5.01e-55 178.0 COG0670@1|root,COG0670@2|Bacteria,1V66F@1239|Firmicutes,4IR6X@91061|Bacilli,3FBMP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the BI1 family ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I AGEJAFOK_00676 748671.LCRIS_01257 4.39e-268 733.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,3F4FK@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) - - - ko:K09963 - - - - ko00000 - - - DUF871 AGEJAFOK_00677 1033837.WANG_1092 5.32e-42 138.0 2DKME@1|root,309X7@2|Bacteria,1U6MA@1239|Firmicutes,4IGE5@91061|Bacilli,3F856@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K18829 - - - - ko00000,ko02048 - - - - AGEJAFOK_00678 1033837.WANG_1091 4.02e-91 266.0 COG2337@1|root,COG2337@2|Bacteria,1UPNV@1239|Firmicutes,4IV86@91061|Bacilli,3F6UK@33958|Lactobacillaceae 91061|Bacilli T Toxin-antitoxin system, toxin component, MazF family - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin AGEJAFOK_00679 1033837.WANG_p1062 9e-132 374.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4IEJ7@91061|Bacilli,3F4SP@33958|Lactobacillaceae 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase AGEJAFOK_00681 1423748.BALB01000002_gene338 2.84e-108 311.0 COG0454@1|root,COG0456@2|Bacteria,1V2BC@1239|Firmicutes,4I1ES@91061|Bacilli,3F5IV@33958|Lactobacillaceae 91061|Bacilli K FR47-like protein - - - - - - - - - - - - Acetyltransf_7 AGEJAFOK_00682 748671.LCRIS_00285 0.0 1023.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,3F439@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon AGEJAFOK_00683 748671.LCRIS_00284 2.77e-248 681.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,3F4C6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus AGEJAFOK_00684 748671.LCRIS_00283 1.37e-214 592.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,3F42B@33958|Lactobacillaceae 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 AGEJAFOK_00685 748671.LCRIS_00282 0.0 1316.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,3F49Z@33958|Lactobacillaceae 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 AGEJAFOK_00686 748671.LCRIS_00281 1.36e-307 837.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,3F4GY@33958|Lactobacillaceae 91061|Bacilli J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C AGEJAFOK_00687 748671.LCRIS_00280 3.95e-82 243.0 COG1098@1|root,COG1098@2|Bacteria,1UI95@1239|Firmicutes,4ISGM@91061|Bacilli,3F6P8@33958|Lactobacillaceae 91061|Bacilli J S1 RNA binding domain - - - ko:K07571 - - - - ko00000 - - - S1 AGEJAFOK_00688 748671.LCRIS_00279 7.52e-78 232.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli,3F76Z@33958|Lactobacillaceae 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC AGEJAFOK_00689 1033837.WANG_1887 7.32e-46 148.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,3F7JX@33958|Lactobacillaceae 91061|Bacilli J S4 domain protein yabO - - - - - - - - - - - S4 AGEJAFOK_00690 748671.LCRIS_00276 0.0 2231.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,3F4KU@33958|Lactobacillaceae 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF AGEJAFOK_00691 748671.LCRIS_00275 1.89e-134 380.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,3F3VZ@33958|Lactobacillaceae 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro AGEJAFOK_00692 748671.LCRIS_00274 2.93e-234 644.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N AGEJAFOK_00693 748671.LCRIS_00273 3.54e-166 464.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,3F3JY@33958|Lactobacillaceae 91061|Bacilli S (CBS) domain - - - - - - - - - - - - CBS AGEJAFOK_00694 748671.LCRIS_00272 2.3e-276 755.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,3F3X2@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N AGEJAFOK_00695 748671.LCRIS_00271 9.39e-80 236.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,3F6HC@33958|Lactobacillaceae 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS AGEJAFOK_00696 748671.LCRIS_00270 0.0 892.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,3F46Q@33958|Lactobacillaceae 91061|Bacilli F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C AGEJAFOK_00697 748671.LCRIS_00269 0.0 898.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,3F4SK@33958|Lactobacillaceae 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M AGEJAFOK_00698 748671.LCRIS_00268 1.07e-52 165.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli,3FCDM@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 AGEJAFOK_00699 748671.LCRIS_00267 0.0 1129.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein dexB - 3.2.1.70 ko:K01215 - - - - ko00000,ko01000 - - - Alpha-amylase,DUF3459,Malt_amylase_C AGEJAFOK_00700 748671.LCRIS_00266 3.87e-199 551.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,3F5C1@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase yhaX - - - - - - - - - - - Hydrolase_3 AGEJAFOK_00701 748671.LCRIS_00265 0.0 1031.0 COG0531@1|root,COG0531@2|Bacteria,1TPJH@1239|Firmicutes,4HUE6@91061|Bacilli,3FCAM@33958|Lactobacillaceae 91061|Bacilli E amino acid - - - - - - - - - - - - AA_permease_2 AGEJAFOK_00702 748671.LCRIS_00264 2.21e-294 803.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,3F4C1@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT AGEJAFOK_00703 748671.LCRIS_00263 7.17e-56 176.0 2ETIJ@1|root,33M2D@2|Bacteria,1W6M0@1239|Firmicutes,4IG2F@91061|Bacilli,3F7HE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00704 748671.LCRIS_00262 1.05e-69 211.0 28QH1@1|root,2ZCZ3@2|Bacteria,1W1MV@1239|Firmicutes,4IG80@91061|Bacilli,3F7TZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00705 748671.LCRIS_00261 3.44e-238 655.0 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HJM8@91061|Bacilli,3F577@33958|Lactobacillaceae 91061|Bacilli C FMN-dependent dehydrogenase - - - - - - - - - - - - FMN_dh AGEJAFOK_00706 748671.LCRIS_00260 2.07e-178 503.0 COG0038@1|root,COG0038@2|Bacteria,1UZ4F@1239|Firmicutes,4HDXG@91061|Bacilli,3F605@33958|Lactobacillaceae 91061|Bacilli P Voltage gated chloride channel - - - - - - - - - - - - Voltage_CLC AGEJAFOK_00707 1423758.BN55_02660 0.0 1004.0 COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4HE0R@91061|Bacilli,3F554@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer cas9 - - ko:K09952 - - - - ko00000,ko01000,ko02048 - - - Cas9-BH,Cas9_PI,Cas9_REC,HNH_4 AGEJAFOK_00708 1423754.BALY01000017_gene389 1.41e-37 136.0 COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae 91061|Bacilli S cog cog1373 - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 AGEJAFOK_00709 748671.LCRIS_01660 2.35e-117 335.0 COG3613@1|root,COG3613@2|Bacteria,1V8XI@1239|Firmicutes,4HJ7M@91061|Bacilli,3FBAU@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr AGEJAFOK_00710 748671.LCRIS_01661 0.0 901.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh AGEJAFOK_00711 748671.LCRIS_01560 0.0 1584.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4ISER@91061|Bacilli,3F3U1@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate pps - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N AGEJAFOK_00713 748671.LCRIS_00457 2.72e-236 650.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4HTTA@91061|Bacilli,3FC7R@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component manL - 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man,PTSIIB_sorb AGEJAFOK_00714 748671.LCRIS_00458 9.65e-181 504.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,3F3V5@33958|Lactobacillaceae 91061|Bacilli G PTS system manY - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor AGEJAFOK_00715 748671.LCRIS_00459 3.51e-222 612.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA AGEJAFOK_00716 748671.LCRIS_00460 1.31e-81 241.0 COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,4HX8Z@91061|Bacilli,3FB56@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF956) - - - - - - - - - - - - DUF956 AGEJAFOK_00717 748671.LCRIS_00461 2.07e-203 563.0 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HAZB@91061|Bacilli,3F3VP@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate AGEJAFOK_00718 748671.LCRIS_00462 7.06e-111 320.0 COG0110@1|root,COG0110@2|Bacteria,1TSQQ@1239|Firmicutes,4HJJ7@91061|Bacilli,3F73Z@33958|Lactobacillaceae 91061|Bacilli S transferase hexapeptide repeat - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2 AGEJAFOK_00719 748671.LCRIS_00463 7.99e-309 844.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease AGEJAFOK_00720 748671.LCRIS_00464 4.47e-58 198.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,3F3RN@33958|Lactobacillaceae 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH AGEJAFOK_00721 748671.LCRIS_00464 0.0 1511.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,3F3RN@33958|Lactobacillaceae 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH AGEJAFOK_00722 748671.LCRIS_00465 0.0 1181.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,3F467@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS AGEJAFOK_00723 748671.LCRIS_00466 0.0 1308.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,3F561@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB AGEJAFOK_00724 748671.LCRIS_00467 0.0 1091.0 COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,3F52S@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit mtlA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIC,PTS_IIB AGEJAFOK_00725 748671.LCRIS_00468 5.75e-103 298.0 COG4668@1|root,COG4668@2|Bacteria,1V77P@1239|Firmicutes,4HIM2@91061|Bacilli,3F6EP@33958|Lactobacillaceae 91061|Bacilli G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane mtlF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02798 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2 AGEJAFOK_00726 748671.LCRIS_00469 2.7e-277 758.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,3F448@33958|Lactobacillaceae 91061|Bacilli C mannitol-1-phosphate 5-dehydrogenase activity mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C AGEJAFOK_00727 748671.LCRIS_00470 5.26e-36 128.0 COG0599@1|root,COG0599@2|Bacteria,1TQGP@1239|Firmicutes,4HH3D@91061|Bacilli,3FBCM@33958|Lactobacillaceae 91061|Bacilli S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD AGEJAFOK_00728 748671.LCRIS_00470 1.78e-100 295.0 COG0599@1|root,COG0599@2|Bacteria,1TQGP@1239|Firmicutes,4HH3D@91061|Bacilli,3FBCM@33958|Lactobacillaceae 91061|Bacilli S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD AGEJAFOK_00729 1033837.WANG_1193 3.36e-42 138.0 29PH8@1|root,30A80@2|Bacteria,1U6B8@1239|Firmicutes,4IG2S@91061|Bacilli,3F7HY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00730 748671.LCRIS_00471 9.05e-78 233.0 COG1051@1|root,COG1051@2|Bacteria,1VAMK@1239|Firmicutes,4HKCB@91061|Bacilli,3F6NU@33958|Lactobacillaceae 91061|Bacilli F Nudix hydrolase apfA - 3.6.1.61 ko:K18445 ko00230,map00230 - R00184 RC00002 ko00000,ko00001,ko01000 - - - NUDIX AGEJAFOK_00731 748671.LCRIS_00472 6.94e-202 559.0 COG1396@1|root,COG1396@2|Bacteria,1UVUA@1239|Firmicutes,4IGAD@91061|Bacilli,3F7YF@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 AGEJAFOK_00732 748671.LCRIS_00474 0.0 1025.0 COG1132@1|root,COG1132@2|Bacteria,1V08F@1239|Firmicutes,4HTAU@91061|Bacilli,3F517@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AGEJAFOK_00733 748671.LCRIS_00475 0.0 1127.0 COG1866@1|root,COG1866@2|Bacteria,1TPXB@1239|Firmicutes,4IS6N@91061|Bacilli,3F4N4@33958|Lactobacillaceae 91061|Bacilli H Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP AGEJAFOK_00734 748671.LCRIS_00476 1.23e-242 677.0 28PUF@1|root,2ZCFF@2|Bacteria,1V2H3@1239|Firmicutes,4HRKS@91061|Bacilli,3F3KN@33958|Lactobacillaceae 91061|Bacilli S TerB-C domain - - - - - - - - - - - - TerB_C,TerB_N AGEJAFOK_00735 748671.LCRIS_00965 5.26e-171 476.0 COG0684@1|root,COG0684@2|Bacteria,1V1ME@1239|Firmicutes,4HGQE@91061|Bacilli,3F5JE@33958|Lactobacillaceae 91061|Bacilli H Aldolase/RraA - - - - - - - - - - - - RraA-like AGEJAFOK_00736 748671.LCRIS_00966 0.0 907.0 COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,3F4RH@33958|Lactobacillaceae 91061|Bacilli P Sodium:sulfate symporter transmembrane region citP - - ko:K03319 - - - - ko00000 2.A.47 - - Na_sulph_symp AGEJAFOK_00737 748671.LCRIS_00103 1.24e-169 473.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HC4I@91061|Bacilli,3F4WS@33958|Lactobacillaceae 91061|Bacilli K SIR2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 AGEJAFOK_00738 748671.LCRIS_00102 1.25e-119 342.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,3F4TG@33958|Lactobacillaceae 91061|Bacilli L 6-O-methylguanine DNA methyltransferase, DNA binding domain adaB GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,Methyltransf_1N AGEJAFOK_00739 748671.LCRIS_00101 1.14e-164 463.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,3FB68@33958|Lactobacillaceae 91061|Bacilli P Integral membrane protein TerC family terC - - - - - - - - - - - TerC AGEJAFOK_00740 748671.LCRIS_00100 7.63e-85 249.0 COG3189@1|root,COG3189@2|Bacteria,1VABH@1239|Firmicutes,4HKI2@91061|Bacilli,3F715@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function, DUF488 yeaO - - - - - - - - - - - DUF488 AGEJAFOK_00741 748671.LCRIS_00099 1.41e-155 436.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HG5E@91061|Bacilli,3F59D@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA glycosylase MPG family yxlJ GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco AGEJAFOK_00742 748671.LCRIS_00098 0.0 1006.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease XK27_05795 - - ko:K17073,ko:K17074 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.20 - - BPD_transp_1,SBP_bac_3 AGEJAFOK_00743 748671.LCRIS_00097 2.89e-173 484.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K17076 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 - - ABC_tran AGEJAFOK_00744 272621.LBA0110 1.4e-191 535.0 COG3152@1|root,COG3152@2|Bacteria,1VDSW@1239|Firmicutes,4HMMJ@91061|Bacilli,3F4C0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF805) yhaH - - - - - - - - - - - DUF805 AGEJAFOK_00745 891391.LAC30SC_00505 2.42e-204 566.0 COG1403@1|root,COG1403@2|Bacteria,1V4V2@1239|Firmicutes,4HI4X@91061|Bacilli,3F4P0@33958|Lactobacillaceae 91061|Bacilli L HNH nucleases - - - - - - - - - - - - HNH,HNH_5 AGEJAFOK_00746 1423748.BALB01000006_gene802 1.11e-154 434.0 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,4HA8H@91061|Bacilli,3F4RZ@33958|Lactobacillaceae 91061|Bacilli S HD containing hydrolase-like enzyme yfbR - - ko:K07023 - - - - ko00000 - - - HD_2 AGEJAFOK_00747 748671.LCRIS_00093 3.67e-225 625.0 COG3405@1|root,COG3405@2|Bacteria,1VCBY@1239|Firmicutes,4HTF0@91061|Bacilli,3F595@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 8 - - - - - - - - - - - - Glyco_hydro_8 AGEJAFOK_00748 748671.LCRIS_00092 4.75e-239 662.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,3F3RY@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3 AGEJAFOK_00749 1423754.BALY01000067_gene768 1.34e-09 59.3 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F6CN@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 AGEJAFOK_00750 1033837.WANG_1665 9.69e-25 92.4 29PIJ@1|root,30AGQ@2|Bacteria,1U6MZ@1239|Firmicutes,4IGEU@91061|Bacilli,3F868@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00751 748671.LCRIS_00089 0.0 1095.0 COG0584@1|root,COG4781@1|root,COG0584@2|Bacteria,COG4781@2|Bacteria,1UGF1@1239|Firmicutes,4HBM4@91061|Bacilli,3FC1C@33958|Lactobacillaceae 91061|Bacilli C Membrane domain of glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,GPDPase_memb AGEJAFOK_00752 1423748.BALB01000006_gene810 3.34e-92 269.0 2F916@1|root,341CT@2|Bacteria,1VY7K@1239|Firmicutes,4HX4B@91061|Bacilli,3F70S@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn AGEJAFOK_00753 748671.LCRIS_00087 7.23e-244 672.0 COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,4HEW7@91061|Bacilli,3F4CJ@33958|Lactobacillaceae 91061|Bacilli P Citrate transporter ysdE - - - - - - - - - - - CitMHS AGEJAFOK_00754 748671.LCRIS_00086 1.43e-125 358.0 COG1704@1|root,COG1704@2|Bacteria,1V4SV@1239|Firmicutes,4IR1I@91061|Bacilli,3FBKP@33958|Lactobacillaceae 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA AGEJAFOK_00755 748671.LCRIS_00085 1.16e-207 575.0 COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,3F40Z@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 AGEJAFOK_00756 748671.LCRIS_00084 1.05e-222 614.0 COG2207@1|root,COG2207@2|Bacteria,1VCUV@1239|Firmicutes,4HGUV@91061|Bacilli,3F48T@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 AGEJAFOK_00757 748671.LCRIS_00083 0.0 867.0 COG0488@1|root,COG0488@2|Bacteria,1UI2R@1239|Firmicutes,4ISG8@91061|Bacilli,3F3WM@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran AGEJAFOK_00758 748671.LCRIS_00082 1.19e-114 333.0 COG0619@1|root,COG0619@2|Bacteria,1V2VE@1239|Firmicutes,4IPQA@91061|Bacilli,3FBE3@33958|Lactobacillaceae 91061|Bacilli P Cobalt transport protein - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ AGEJAFOK_00759 748671.LCRIS_00081 1.09e-223 615.0 COG2267@1|root,COG2267@2|Bacteria,1TRMT@1239|Firmicutes,4HE23@91061|Bacilli,3F40N@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepI - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 AGEJAFOK_00760 1423754.BALY01000048_gene1063 6.67e-115 339.0 COG4990@1|root,COG4990@2|Bacteria,1V7GB@1239|Firmicutes,4I28M@91061|Bacilli,3F5VT@33958|Lactobacillaceae 91061|Bacilli G Peptidase_C39 like family - - - - - - - - - - - - CW_binding_1,Peptidase_C39_2,SH3_8,SLAP AGEJAFOK_00761 1423754.BALY01000032_gene481 2.16e-207 580.0 COG0791@1|root,COG0791@2|Bacteria,1VB5V@1239|Firmicutes,4HN9W@91061|Bacilli,3F3P4@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family - - - - - - - - - - - - NLPC_P60,PG_binding_1,SLAP AGEJAFOK_00762 748671.LCRIS_00080 1.93e-32 117.0 COG4990@1|root,COG4990@2|Bacteria,1V7GB@1239|Firmicutes,4I28M@91061|Bacilli,3F5VT@33958|Lactobacillaceae 91061|Bacilli G Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2,SH3_8,SLAP AGEJAFOK_00763 748671.LCRIS_01714 2.93e-195 541.0 2DKHZ@1|root,309I2@2|Bacteria,1U54Y@1239|Firmicutes,4IEW4@91061|Bacilli,3F4PH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00764 1545701.LACWKB10_1305 6.16e-14 73.6 2A3Q0@1|root,30S7H@2|Bacteria,1U63K@1239|Firmicutes,4IFT0@91061|Bacilli,3F6YD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00765 1317122.ATO12_03525 3.48e-105 320.0 COG0732@1|root,COG0732@2|Bacteria,4NIPK@976|Bacteroidetes,1I56H@117743|Flavobacteriia 976|Bacteroidetes V Type I restriction modification DNA specificity domain - - - - - - - - - - - - Methylase_S AGEJAFOK_00766 698961.CGSMWGv6119V5_02276 2.96e-176 512.0 COG0286@1|root,COG0286@2|Bacteria,2GP6Y@201174|Actinobacteria,4D0BW@85004|Bifidobacteriales 201174|Actinobacteria V N-6 DNA Methylase - - - - - - - - - - - - Methylase_S,N6_Mtase AGEJAFOK_00767 748671.LCRIS_00059 4.19e-92 269.0 COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,4HISW@91061|Bacilli,3F6ZA@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins def2 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase AGEJAFOK_00768 748671.LCRIS_00058 1.05e-289 791.0 COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli,3F47M@33958|Lactobacillaceae 91061|Bacilli N Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG AGEJAFOK_00769 748671.LCRIS_00057 6.72e-261 715.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX - - - - - - - - - - - Beta-lactamase,SLH AGEJAFOK_00770 748671.LCRIS_00056 0.0 1087.0 COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII AGEJAFOK_00771 748671.LCRIS_00056 9.56e-274 771.0 COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII AGEJAFOK_00772 748671.LCRIS_00055 0.0 953.0 COG0531@1|root,COG0531@2|Bacteria,1TRUM@1239|Firmicutes,4HE3V@91061|Bacilli,3F3Y1@33958|Lactobacillaceae 91061|Bacilli E amino acid - - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 AGEJAFOK_00773 748671.LCRIS_00054 1.2e-202 560.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,3F4GK@33958|Lactobacillaceae 91061|Bacilli L exodeoxyribonuclease III xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos AGEJAFOK_00775 1423767.BALU01000001_gene1383 1.44e-07 54.7 29W6X@1|root,30HS4@2|Bacteria,1UHXX@1239|Firmicutes,4ISAB@91061|Bacilli,3F8TA@33958|Lactobacillaceae 91061|Bacilli S YSIRK type signal peptide - - - - - - - - - - - - YSIRK_signal AGEJAFOK_00776 748671.LCRIS_00051 2.27e-245 673.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HH0S@91061|Bacilli,3FB6C@33958|Lactobacillaceae 91061|Bacilli C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhA - 1.1.1.28 ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 M00651 R00704 RC00044 ko00000,ko00001,ko00002,ko01000,ko01504 - - - 2-Hacid_dh,2-Hacid_dh_C AGEJAFOK_00777 891391.LAC30SC_08700 7.01e-103 305.0 COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,3F5HY@33958|Lactobacillaceae 91061|Bacilli H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 AGEJAFOK_00778 891391.LAC30SC_08705 1.9e-158 446.0 COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,3F4AQ@33958|Lactobacillaceae 91061|Bacilli I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 AGEJAFOK_00779 891391.LAC30SC_08710 2.42e-163 459.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,3F496@33958|Lactobacillaceae 91061|Bacilli I alpha subunit accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA AGEJAFOK_00780 891391.LAC30SC_08715 4.9e-180 503.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,3F3T6@33958|Lactobacillaceae 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans AGEJAFOK_00781 891391.LAC30SC_08720 3.44e-300 822.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,3F3PT@33958|Lactobacillaceae 91061|Bacilli I Acetyl-CoA carboxylase biotin carboxylase subunit accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 AGEJAFOK_00782 891391.LAC30SC_08725 7.28e-80 239.0 COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,3FCD5@33958|Lactobacillaceae 91061|Bacilli I FabA-like domain fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA AGEJAFOK_00783 891391.LAC30SC_08730 3.17e-67 207.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,3F7M1@33958|Lactobacillaceae 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl AGEJAFOK_00784 891391.LAC30SC_08735 2.53e-268 738.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,3F51H@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt AGEJAFOK_00785 891391.LAC30SC_08740 1.4e-137 393.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,3F4RI@33958|Lactobacillaceae 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 AGEJAFOK_00786 891391.LAC30SC_08745 2.77e-177 499.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,3F3W9@33958|Lactobacillaceae 91061|Bacilli I Malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 AGEJAFOK_00787 891391.LAC30SC_08750 4.22e-41 136.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli,3F7ZJ@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding AGEJAFOK_00788 525365.HMPREF0548_0281 1.98e-47 161.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,3F3XP@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C AGEJAFOK_00789 891391.LAC30SC_08755 9.89e-112 328.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,3F3XP@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C AGEJAFOK_00790 891391.LAC30SC_08760 8.44e-65 200.0 COG0764@1|root,COG0764@2|Bacteria 2|Bacteria I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA AGEJAFOK_00791 891391.LAC30SC_08765 1.67e-95 278.0 COG1846@1|root,COG1846@2|Bacteria,1VDIT@1239|Firmicutes,4HNFP@91061|Bacilli,3F6SX@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 AGEJAFOK_00792 1033837.WANG_1626 6.14e-107 318.0 29NJE@1|root,30RS9@2|Bacteria,1U60N@1239|Firmicutes,4IFPF@91061|Bacilli,3F6SP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_19 AGEJAFOK_00793 748671.LCRIS_01379 3.23e-59 183.0 2CE9Z@1|root,33CNB@2|Bacteria,1VNIV@1239|Firmicutes,4HRR9@91061|Bacilli,3F7UX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00794 748671.LCRIS_01378 0.0 982.0 COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,3F53D@33958|Lactobacillaceae 91061|Bacilli S ABC transporter yjcA - - ko:K19350 ko02010,map02010 - - - ko00000,ko00001,ko01504,ko02000 3.A.1.121 - - ABC_tran,ABC_tran_Xtn AGEJAFOK_00795 575606.HMPREF0525_01471 6.24e-210 579.0 COG3039@1|root,COG3039@2|Bacteria,1UZVA@1239|Firmicutes,4HH09@91061|Bacilli,3F4KP@33958|Lactobacillaceae 91061|Bacilli L An automated process has identified a potential problem with this gene model - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_3 AGEJAFOK_00797 748671.LCRIS_01795 1.13e-35 121.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,3F85E@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 AGEJAFOK_00798 1280666.ATVS01000022_gene3392 0.000868 45.8 2C3W7@1|root,33JCH@2|Bacteria,1VN85@1239|Firmicutes,24WS5@186801|Clostridia,4BZRM@830|Butyrivibrio 186801|Clostridia - - - - - - - - - - - - - - - AGEJAFOK_00799 748671.LCRIS_01798 2.04e-277 757.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,3F49P@33958|Lactobacillaceae 91061|Bacilli E methionine synthase, vitamin-B12 independent metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 AGEJAFOK_00800 748671.LCRIS_01799 6.6e-115 328.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,3F4W2@33958|Lactobacillaceae 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS AGEJAFOK_00801 748671.LCRIS_01800 0.0 919.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,3F4EG@33958|Lactobacillaceae 91061|Bacilli C L-lactate permease lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm AGEJAFOK_00802 748671.LCRIS_01801 1.59e-172 483.0 COG1108@1|root,COG1108@2|Bacteria,1V0SX@1239|Firmicutes,4HE09@91061|Bacilli,3F4BC@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 AGEJAFOK_00803 748671.LCRIS_01802 1.63e-152 428.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,3F49M@33958|Lactobacillaceae 91061|Bacilli P ABC transporter adcC - - ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 M00242,M00244,M00319 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran AGEJAFOK_00804 748671.LCRIS_01803 9.9e-209 577.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,3F4B9@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA AGEJAFOK_00805 748671.LCRIS_01804 4.47e-56 175.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,3F72A@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 AGEJAFOK_00806 748671.LCRIS_01805 0.0 1246.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F44C@33958|Lactobacillaceae 91061|Bacilli GT Phosphotransferase System fruA - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB AGEJAFOK_00807 748671.LCRIS_01806 2.18e-215 595.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,3F3SG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB AGEJAFOK_00808 748671.LCRIS_01807 3.14e-175 489.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,3F3JB@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR AGEJAFOK_00809 1423767.BALU01000001_gene1423 6.39e-279 764.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,3F3KA@33958|Lactobacillaceae 91061|Bacilli CP ABC-2 family transporter protein natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 AGEJAFOK_00810 891391.LAC30SC_09680 3.09e-212 586.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,3F4J8@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 AGEJAFOK_00811 891391.LAC30SC_09690 3.41e-88 259.0 29PEP@1|root,30ACV@2|Bacteria,1U6H1@1239|Firmicutes,4IG99@91061|Bacilli,3F7WP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00812 891391.LAC30SC_09695 2.52e-32 112.0 2B46M@1|root,30ADR@2|Bacteria,1U6I8@1239|Firmicutes,4IGAJ@91061|Bacilli,3F7YW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00813 1423767.BALU01000001_gene1429 6.32e-42 137.0 COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HPRB@91061|Bacilli,3F802@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 AGEJAFOK_00814 891391.LAC30SC_09705 2.13e-63 197.0 29NUX@1|root,309T1@2|Bacteria,1U5MT@1239|Firmicutes,4IFCK@91061|Bacilli,3F67G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2975 AGEJAFOK_00815 891391.LAC30SC_09705 7.66e-32 115.0 29NUX@1|root,309T1@2|Bacteria,1U5MT@1239|Firmicutes,4IFCK@91061|Bacilli,3F67G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2975 AGEJAFOK_00816 1423767.BALU01000001_gene1431 7.87e-30 106.0 29PVE@1|root,30ATN@2|Bacteria,1U739@1239|Firmicutes,4IGXU@91061|Bacilli,3F8X7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00820 272621.LBA1793 5.02e-180 516.0 2DWQH@1|root,341F6@2|Bacteria,1W6SH@1239|Firmicutes,4HX74@91061|Bacilli 91061|Bacilli - - blpT - - - - - - - - - - - Thioredoxin AGEJAFOK_00821 891391.LAC30SC_09740 7.86e-138 390.0 COG0845@1|root,COG0845@2|Bacteria,1V5C8@1239|Firmicutes,4HHKB@91061|Bacilli,3F5W4@33958|Lactobacillaceae 91061|Bacilli M Transport protein ComB mesE - - ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112,8.A.1,8.A.1.4.2 - - HlyD_3 AGEJAFOK_00822 891391.LAC30SC_09745 1.85e-141 419.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,3F3QF@33958|Lactobacillaceae 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 AGEJAFOK_00823 748671.LCRIS_00914 4.36e-93 273.0 COG0454@1|root,COG0456@2|Bacteria,1V6XH@1239|Firmicutes,4HYH2@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) domain - - - ko:K03827 - - - - ko00000,ko01000 - - - Acetyltransf_10 AGEJAFOK_00824 1033837.WANG_0628 5.83e-24 99.8 COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,4HEHY@91061|Bacilli,3F3KX@33958|Lactobacillaceae 91061|Bacilli V MATE efflux family protein mepA - - ko:K18908 - M00705 - - ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 - - MatE AGEJAFOK_00825 748671.LCRIS_00915 5.08e-229 637.0 COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,4HEHY@91061|Bacilli,3F3KX@33958|Lactobacillaceae 91061|Bacilli V MATE efflux family protein mepA - - ko:K18908 - M00705 - - ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 - - MatE AGEJAFOK_00826 748671.LCRIS_01901 1e-131 376.0 COG2365@1|root,COG2365@2|Bacteria,1W78R@1239|Firmicutes,4IEVA@91061|Bacilli,3F4QQ@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 AGEJAFOK_00827 748671.LCRIS_01907 0.0 1004.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N AGEJAFOK_00828 1423748.BALB01000024_gene1759 3.66e-186 518.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin AGEJAFOK_00829 1423748.BALB01000024_gene1764 1.74e-248 687.0 COG2211@1|root,COG2211@2|Bacteria,1UI0Q@1239|Firmicutes,4HPV9@91061|Bacilli,3FBU4@33958|Lactobacillaceae 91061|Bacilli G Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 AGEJAFOK_00830 1423748.BALB01000041_gene2025 5.63e-171 487.0 COG1132@1|root,COG1132@2|Bacteria,1UYYQ@1239|Firmicutes,4HWP7@91061|Bacilli,3F5DU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran AGEJAFOK_00831 748671.LCRIS_01877 3.65e-285 781.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon AGEJAFOK_00832 326425.lhe_1039 1.83e-91 286.0 COG1132@1|root,COG1132@2|Bacteria,1UYYQ@1239|Firmicutes,4HWP7@91061|Bacilli,3F5DU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran AGEJAFOK_00833 1423748.BALB01000041_gene2026 6.69e-84 248.0 COG3077@1|root,COG3077@2|Bacteria,1U7JP@1239|Firmicutes,4IHGU@91061|Bacilli,3F9U1@33958|Lactobacillaceae 91061|Bacilli L RelB antitoxin - - - - - - - - - - - - RelB AGEJAFOK_00834 1423748.BALB01000041_gene2027 1.51e-168 470.0 COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli,3F4CH@33958|Lactobacillaceae 91061|Bacilli S glutamine amidotransferase cobQ - - ko:K07009 - - - - ko00000 - - - GATase_3 AGEJAFOK_00835 748671.LCRIS_01917 8.6e-108 311.0 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HZ6Z@91061|Bacilli,3FC1P@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 AGEJAFOK_00838 748671.LCRIS_01919 1.02e-200 556.0 2DKJE@1|root,309Q1@2|Bacteria,1U5GX@1239|Firmicutes,4IF7Q@91061|Bacilli,3F5X8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_3 AGEJAFOK_00839 1423758.BN55_06170 1.03e-07 56.2 29PQT@1|root,30AP0@2|Bacteria,1U6XK@1239|Firmicutes,4IGRW@91061|Bacilli,3F8P7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00840 748671.LCRIS_01920 5.51e-47 152.0 2BPU5@1|root,32IMK@2|Bacteria,1U821@1239|Firmicutes,4IHZE@91061|Bacilli,3FAFK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00841 748671.LCRIS_01921 4.48e-206 572.0 COG0697@1|root,COG0697@2|Bacteria,1TRTP@1239|Firmicutes,4HB3F@91061|Bacilli,3FBJS@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA AGEJAFOK_00842 748671.LCRIS_01922 3.18e-209 579.0 COG0697@1|root,COG0697@2|Bacteria,1TRTP@1239|Firmicutes,4HB3F@91061|Bacilli,3FBJS@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA AGEJAFOK_00843 272621.LBA1887 1.07e-177 499.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F5NA@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family yicL - - - - - - - - - - - EamA AGEJAFOK_00844 748671.LCRIS_01924 1.32e-137 390.0 2A5BR@1|root,30U1B@2|Bacteria,1UQ43@1239|Firmicutes,4IFET@91061|Bacilli,3F6BQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00845 748671.LCRIS_01925 9.07e-143 403.0 29NPC@1|root,309M9@2|Bacteria,1U5BC@1239|Firmicutes,4IF2P@91061|Bacilli,3F5FH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00846 748671.LCRIS_01926 1.84e-238 656.0 COG1434@1|root,COG1434@2|Bacteria,1UR34@1239|Firmicutes,4HDF2@91061|Bacilli,3F4J5@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 AGEJAFOK_00847 748671.LCRIS_01927 0.0 910.0 COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,3F4UR@33958|Lactobacillaceae 91061|Bacilli S ATPases associated with a variety of cellular activities yheS_2 - - ko:K18231,ko:K19349 ko02010,map02010 - - - br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.2,3.A.1.121.3 - - ABC_tran,ABC_tran_Xtn AGEJAFOK_00848 748671.LCRIS_01928 6.77e-111 319.0 2DKKP@1|root,309U8@2|Bacteria,1U5Q4@1239|Firmicutes,4IFEC@91061|Bacilli,3F6AJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00849 748671.LCRIS_01929 1.09e-74 224.0 29NYM@1|root,309WQ@2|Bacteria,1U5UZ@1239|Firmicutes,4IFIM@91061|Bacilli,3F6IU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00850 748671.LCRIS_01930 7.26e-35 121.0 COG5294@1|root,COG5294@2|Bacteria,1VZPI@1239|Firmicutes,4HYUI@91061|Bacilli,3F82Y@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria - - - - - - - - - - - - - AGEJAFOK_00851 1033837.WANG_1419 2.27e-71 215.0 COG4226@1|root,COG4226@2|Bacteria,1U5BB@1239|Firmicutes,4I0P7@91061|Bacilli,3F8H6@33958|Lactobacillaceae 91061|Bacilli S protein encoded in hypervariable junctions of pilus gene clusters - - - - - - - - - - - - HicB AGEJAFOK_00852 1033837.WANG_1420 1.01e-38 130.0 2E9T0@1|root,333Z2@2|Bacteria,1VHPB@1239|Firmicutes,4IHTA@91061|Bacilli,3FA8M@33958|Lactobacillaceae 91061|Bacilli S HicA toxin of bacterial toxin-antitoxin, - - - - - - - - - - - - HicA_toxin AGEJAFOK_00854 748671.LCRIS_00160 0.0 1300.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F4CX@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N AGEJAFOK_00855 748671.LCRIS_00561 8.97e-47 151.0 29PX4@1|root,30AVF@2|Bacteria,1U75H@1239|Firmicutes,4IH06@91061|Bacilli,3F907@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00856 748671.LCRIS_00560 5.94e-200 553.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H9XJ@91061|Bacilli,3FB4Q@33958|Lactobacillaceae 91061|Bacilli S reductase - - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red AGEJAFOK_00857 748671.LCRIS_00559 6.13e-110 316.0 COG0454@1|root,COG0456@2|Bacteria,1VEW7@1239|Firmicutes,4HQMJ@91061|Bacilli,3FCFM@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 AGEJAFOK_00859 891391.LAC30SC_08780 3.74e-180 511.0 COG0477@1|root,COG2814@2|Bacteria,1W01A@1239|Firmicutes,4HZ1U@91061|Bacilli,3F4S8@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 AGEJAFOK_00860 748671.LCRIS_00050 3.16e-192 533.0 COG0561@1|root,COG0561@2|Bacteria,1U5C1@1239|Firmicutes,4IF34@91061|Bacilli,3F5HG@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 AGEJAFOK_00861 748671.LCRIS_00049 0.0 1271.0 COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,4HAS9@91061|Bacilli,3F4B4@33958|Lactobacillaceae 91061|Bacilli J elongation factor G fusA1 - - - - - - - - - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU AGEJAFOK_00862 748671.LCRIS_00045 9.52e-205 566.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3F3PW@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase yvgN - - - - - - - - - - - Aldo_ket_red AGEJAFOK_00863 748671.LCRIS_00044 5.49e-97 288.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HK15@91061|Bacilli,3F6FH@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA AGEJAFOK_00864 748671.LCRIS_00044 7.93e-63 199.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HK15@91061|Bacilli,3F6FH@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA AGEJAFOK_00865 748671.LCRIS_00043 7.75e-170 474.0 COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,3F4NI@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase ysaA - 3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 - - - HAD_2 AGEJAFOK_00866 748671.LCRIS_00040 3.35e-223 617.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter ABC-SBP - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind AGEJAFOK_00867 748671.LCRIS_00039 4.76e-168 474.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 AGEJAFOK_00868 748671.LCRIS_00038 8.64e-176 490.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F3NW@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran AGEJAFOK_00869 748671.LCRIS_01977 8.58e-60 186.0 2BZTJ@1|root,30A2T@2|Bacteria,1U644@1239|Firmicutes,4IFTP@91061|Bacilli,3F6ZQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00870 525365.HMPREF0548_1406 3.56e-85 263.0 29DXA@1|root,300V7@2|Bacteria,1U59E@1239|Firmicutes,4IF0P@91061|Bacilli,3F59A@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP AGEJAFOK_00871 1423748.BALB01000047_gene2064 1.08e-79 253.0 29NJD@1|root,309JD@2|Bacteria,1U580@1239|Firmicutes,4IEZA@91061|Bacilli,3F53B@33958|Lactobacillaceae 91061|Bacilli S Bacteriocin helveticin-J - - - - - - - - - - - - Helveticin_J AGEJAFOK_00872 525365.HMPREF0548_1860 7.61e-59 184.0 29P23@1|root,30A09@2|Bacteria,1U60S@1239|Firmicutes,4IFPI@91061|Bacilli,3F6ST@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00873 1423790.BN53_01225 1.53e-54 172.0 COG1396@1|root,COG1396@2|Bacteria,1VEP9@1239|Firmicutes,4HPCR@91061|Bacilli,3F871@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_26,HTH_3 AGEJAFOK_00874 748671.LCRIS_00010 2.81e-102 296.0 COG2856@1|root,COG2856@2|Bacteria,1W1K0@1239|Firmicutes,4IGCD@91061|Bacilli,3F81Z@33958|Lactobacillaceae 91061|Bacilli E Zn peptidase - - - - - - - - - - - - Peptidase_M48,Peptidase_M78 AGEJAFOK_00875 748671.LCRIS_00037 1.06e-311 850.0 COG2211@1|root,COG2211@2|Bacteria,1TRP7@1239|Firmicutes,4HCUK@91061|Bacilli,3F3YZ@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 AGEJAFOK_00876 748671.LCRIS_00036 2.55e-26 97.4 2AR30@1|root,30ATE@2|Bacteria,1U731@1239|Firmicutes,4IGXJ@91061|Bacilli,3F8WS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00877 748671.LCRIS_00035 1.95e-134 380.0 COG2755@1|root,COG2755@2|Bacteria,1VAT2@1239|Firmicutes,4HKYJ@91061|Bacilli,3F5TI@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 AGEJAFOK_00878 748671.LCRIS_00034 2.54e-225 623.0 COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,3F46E@33958|Lactobacillaceae 91061|Bacilli K AI-2E family transporter ydbI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport AGEJAFOK_00879 748671.LCRIS_00033 3e-118 354.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 AGEJAFOK_00880 748671.LCRIS_00033 3.26e-292 805.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 AGEJAFOK_00881 748671.LCRIS_00029 5.76e-66 228.0 COG0810@1|root,COG0810@2|Bacteria,1UHXS@1239|Firmicutes,4ISA8@91061|Bacilli,3F7D9@33958|Lactobacillaceae 91061|Bacilli M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal AGEJAFOK_00883 748671.LCRIS_00511 7.62e-306 836.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase npr - 1.11.1.1 ko:K05910 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim AGEJAFOK_00884 748671.LCRIS_00173 1.48e-14 70.9 29QPJ@1|root,30BP9@2|Bacteria,1U8EN@1239|Firmicutes,4IICH@91061|Bacilli,3FAWE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00885 1423748.BALB01000008_gene918 5.24e-31 111.0 COG5464@1|root,COG5464@2|Bacteria,1U8FG@1239|Firmicutes,4IIDC@91061|Bacilli,3FAXC@33958|Lactobacillaceae 91061|Bacilli S transposase or invertase - - - - - - - - - - - - - AGEJAFOK_00886 748671.LCRIS_00508 9.6e-309 847.0 2DKHC@1|root,309G6@2|Bacteria,1U50G@1239|Firmicutes,4IESF@91061|Bacilli,3F3S2@33958|Lactobacillaceae 91061|Bacilli S SLAP domain slpX - - - - - - - - - - - SLAP AGEJAFOK_00887 748671.LCRIS_00507 1.43e-186 520.0 COG1737@1|root,COG1737@2|Bacteria,1UYAM@1239|Firmicutes,4HVUK@91061|Bacilli,3FC4F@33958|Lactobacillaceae 91061|Bacilli K SIS domain - - - - - - - - - - - - HTH_6,SIS AGEJAFOK_00888 748671.LCRIS_00506 3.01e-154 434.0 COG0120@1|root,COG0120@2|Bacteria,1W0HS@1239|Firmicutes,4HZEY@91061|Bacilli,3F757@33958|Lactobacillaceae 91061|Bacilli G Ribose 5-phosphate isomerase A (phosphoriboisomerase A) rpiA1 - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A AGEJAFOK_00889 748671.LCRIS_00505 1.03e-237 653.0 COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli,3F4XH@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold XK27_10475 - - - - - - - - - - - GFO_IDH_MocA AGEJAFOK_00890 748671.LCRIS_00504 1.93e-266 731.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase araT - 2.6.1.57 ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 M00024,M00025,M00034,M00040,M00525 R00694,R00734,R01731,R04467,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 AGEJAFOK_00892 1423767.BALU01000012_gene177 0.0 1677.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli,3F4E0@33958|Lactobacillaceae 91061|Bacilli P COG0474 Cation transport ATPase mgtA - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 AGEJAFOK_00894 748671.LCRIS_00496 2.67e-148 419.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3F4E3@33958|Lactobacillaceae 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ1 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD AGEJAFOK_00895 748671.LCRIS_00495 1.9e-153 431.0 COG1359@1|root,COG1359@2|Bacteria,1VVR5@1239|Firmicutes,4HWFJ@91061|Bacilli,3F5NS@33958|Lactobacillaceae 91061|Bacilli G Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM,His_Phos_1 AGEJAFOK_00896 748671.LCRIS_00494 9.01e-115 330.0 COG0406@1|root,COG0406@2|Bacteria,1V4Y8@1239|Firmicutes,4IF2Q@91061|Bacilli,3F5FJ@33958|Lactobacillaceae 91061|Bacilli G Histidine phosphatase superfamily (branch 1) - - - - - - - - - - - - His_Phos_1 AGEJAFOK_00897 748671.LCRIS_00493 8.92e-136 384.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli,3F4JB@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 AGEJAFOK_00898 748671.LCRIS_00492 5.68e-211 588.0 COG1196@1|root,COG1196@2|Bacteria,1U570@1239|Firmicutes,4IEYI@91061|Bacilli,3F4ZJ@33958|Lactobacillaceae 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - - AGEJAFOK_00899 748671.LCRIS_00491 1.33e-130 374.0 COG1388@1|root,COG1388@2|Bacteria,1V773@1239|Firmicutes,4HIJG@91061|Bacilli,3F3JQ@33958|Lactobacillaceae 91061|Bacilli M LysM domain protein - - - - - - - - - - - - LysM,SLAP AGEJAFOK_00900 272621.LBA0491 2.57e-108 323.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F3Q4@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane licC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - iYO844.BSU38390 PTS_EIIC AGEJAFOK_00901 272621.LBA0491 6.31e-99 298.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F3Q4@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane licC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - iYO844.BSU38390 PTS_EIIC AGEJAFOK_00902 748671.LCRIS_00489 1.83e-22 92.4 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F3Q4@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane licC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - iYO844.BSU38390 PTS_EIIC AGEJAFOK_00903 1423748.BALB01000016_gene1454 1.25e-17 73.9 29PR7@1|root,30APF@2|Bacteria,1U6Y4@1239|Firmicutes,4IGSA@91061|Bacilli,3F8PS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00904 748671.LCRIS_00486 2.77e-220 606.0 COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,4HF40@91061|Bacilli,3F401@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase pphA - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos AGEJAFOK_00905 748671.LCRIS_00485 1.04e-41 136.0 2C7HR@1|root,30AK4@2|Bacteria,1U6T5@1239|Firmicutes,4IGKW@91061|Bacilli,3F8FZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00907 748671.LCRIS_00483 3.65e-90 264.0 2F916@1|root,309SE@2|Bacteria,1U5KS@1239|Firmicutes,4IFBR@91061|Bacilli,3F65Y@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn AGEJAFOK_00908 1423758.BN55_09680 0.0 2183.0 COG3064@1|root,COG3064@2|Bacteria,1UHXY@1239|Firmicutes,4ISAC@91061|Bacilli,3F52E@33958|Lactobacillaceae 91061|Bacilli M Rib/alpha-like repeat - - - - - - - - - - - - Gram_pos_anchor,Rib,YSIRK_signal AGEJAFOK_00909 748671.LCRIS_01897 0.0 1138.0 COG0366@1|root,COG0366@2|Bacteria,1UY2T@1239|Firmicutes,4HBRE@91061|Bacilli,3FC10@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain malA1 - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Malt_amylase_C AGEJAFOK_00910 748671.LCRIS_01896 0.0 1211.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,3F41N@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C AGEJAFOK_00911 748671.LCRIS_01895 0.0 1487.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,3F3PG@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 65, central catalytic mapA - 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m AGEJAFOK_00912 748671.LCRIS_01894 7.7e-149 419.0 COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HF3K@91061|Bacilli,3F4ST@33958|Lactobacillaceae 91061|Bacilli S beta-phosphoglucomutase pgmB - 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 AGEJAFOK_00913 748671.LCRIS_01893 5.75e-266 728.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,3FC3D@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 AGEJAFOK_00914 748671.LCRIS_01892 2.73e-282 773.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HAK6@91061|Bacilli,3F50T@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_8 AGEJAFOK_00915 748671.LCRIS_01891 0.0 866.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,3F4J1@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component malF - - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 AGEJAFOK_00916 748671.LCRIS_01890 1.39e-197 548.0 COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli,3F4NP@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease malG - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 AGEJAFOK_00917 324831.LGAS_0400 4.73e-84 259.0 29NJE@1|root,30GE4@2|Bacteria,1UFUT@1239|Firmicutes,4IEZ0@91061|Bacilli,3F51E@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 AGEJAFOK_00922 1423767.BALU01000007_gene641 1.45e-133 384.0 2DKHZ@1|root,309I2@2|Bacteria,1U54Y@1239|Firmicutes,4IEW4@91061|Bacilli,3F4PH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00923 1033837.WANG_0214 2.74e-06 48.9 COG1672@1|root,COG1672@2|Bacteria,1V0EH@1239|Firmicutes,4HXBI@91061|Bacilli,3F4KW@33958|Lactobacillaceae 91061|Bacilli S PFAM Archaeal ATPase - - - - - - - - - - - - AAA_14,AAA_16,ATPase_2 AGEJAFOK_00924 748671.LCRIS_01562 5.46e-182 506.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F4J6@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP AGEJAFOK_00925 748671.LCRIS_01561 7.62e-134 379.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli,3F4JB@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 AGEJAFOK_00927 748671.LCRIS_00950 6.04e-49 155.0 29PA0@1|root,30A85@2|Bacteria,1U6BF@1239|Firmicutes,4IG31@91061|Bacilli,3F7IE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00928 748671.LCRIS_00951 0.0 999.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F514@33958|Lactobacillaceae 91061|Bacilli P ABC transporter - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran AGEJAFOK_00929 748671.LCRIS_00952 0.0 981.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F46B@33958|Lactobacillaceae 91061|Bacilli V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran AGEJAFOK_00930 748671.LCRIS_00953 4.17e-314 858.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yifK - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease AGEJAFOK_00931 748671.LCRIS_00954 8.21e-228 627.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,3F3SB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt AGEJAFOK_00932 748671.LCRIS_00955 1.08e-116 334.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,3F6Y4@33958|Lactobacillaceae 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 AGEJAFOK_00933 748671.LCRIS_00956 0.0 1479.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli,3F4Y1@33958|Lactobacillaceae 91061|Bacilli P E1-E2 ATPase aha1 - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase AGEJAFOK_00934 748671.LCRIS_00957 2.57e-223 615.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HK7D@91061|Bacilli,3FC9U@33958|Lactobacillaceae 91061|Bacilli F DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 AGEJAFOK_00935 748671.LCRIS_00958 5.31e-206 569.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 AGEJAFOK_00936 748671.LCRIS_00959 5.74e-243 669.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,3F3U5@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL AGEJAFOK_00937 272621.LBA0906 2.34e-122 353.0 COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,4HBEV@91061|Bacilli,3F48A@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 AGEJAFOK_00938 748671.LCRIS_00961 0.0 919.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,3F3K0@33958|Lactobacillaceae 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 AGEJAFOK_00939 748671.LCRIS_00962 0.0 902.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,3F3KJ@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain frdA - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2 AGEJAFOK_00940 748671.LCRIS_00963 1.66e-217 600.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N AGEJAFOK_00941 748671.LCRIS_00964 0.0 871.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F5DQ@33958|Lactobacillaceae 91061|Bacilli E Peptidase C1-like family pepC4 - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 AGEJAFOK_00942 748671.LCRIS_00847 1.75e-211 584.0 COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,4HBUD@91061|Bacilli,3F5GQ@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat AGEJAFOK_00943 748671.LCRIS_00846 0.0 1023.0 COG5527@1|root,COG5527@2|Bacteria,1U5J6@1239|Firmicutes,4IFA3@91061|Bacilli,3F62N@33958|Lactobacillaceae 91061|Bacilli L Nuclease-related domain - - - - - - - - - - - - NERD,Rep_3 AGEJAFOK_00944 748671.LCRIS_00845 0.0 1510.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F44X@33958|Lactobacillaceae 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 AGEJAFOK_00945 748671.LCRIS_00844 2.31e-148 418.0 COG0457@1|root,COG0457@2|Bacteria,1VFGR@1239|Firmicutes,4IBSH@91061|Bacilli,3F4MD@33958|Lactobacillaceae 91061|Bacilli S repeat protein - - - - - - - - - - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 AGEJAFOK_00946 748671.LCRIS_00843 4.7e-163 455.0 COG0406@1|root,COG0406@2|Bacteria,1V7EZ@1239|Firmicutes,4HJCK@91061|Bacilli,3FBD9@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family pgm - - - - - - - - - - - His_Phos_1 AGEJAFOK_00947 748671.LCRIS_00842 4.47e-278 759.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,3F4N5@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans AGEJAFOK_00948 748671.LCRIS_00841 9.98e-75 223.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli,3F7E3@33958|Lactobacillaceae 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 AGEJAFOK_00949 748671.LCRIS_00840 1.62e-276 756.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,3F3RF@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 AGEJAFOK_00950 748671.LCRIS_00839 2.05e-163 457.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,3F4HE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 AGEJAFOK_00951 748671.LCRIS_00838 1.22e-55 174.0 2B5KT@1|root,31YFV@2|Bacteria,1U6T4@1239|Firmicutes,4IGKV@91061|Bacilli,3F8FY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00952 748671.LCRIS_00837 5.18e-134 379.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,3F53J@33958|Lactobacillaceae 91061|Bacilli L ADP-ribose pyrophosphatase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX AGEJAFOK_00953 748671.LCRIS_00836 2.32e-43 140.0 COG1278@1|root,COG1278@2|Bacteria,1U6DB@1239|Firmicutes,4IG52@91061|Bacilli,3F7NC@33958|Lactobacillaceae 91061|Bacilli K 'Cold-shock' DNA-binding domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD AGEJAFOK_00954 748671.LCRIS_00835 0.0 1788.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,3F3X4@33958|Lactobacillaceae 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS AGEJAFOK_00955 748671.LCRIS_00834 6.3e-138 396.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,3F4IN@33958|Lactobacillaceae 91061|Bacilli D DivIVA domain protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA AGEJAFOK_00956 748671.LCRIS_00833 4.01e-192 533.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,3F48W@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein ylmH - - - - - - - - - - - S4 AGEJAFOK_00957 748671.LCRIS_00832 2.42e-60 186.0 COG0762@1|root,COG0762@2|Bacteria,1U6JG@1239|Firmicutes,4IGBY@91061|Bacilli,3F818@33958|Lactobacillaceae 91061|Bacilli S YGGT family yggT - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT AGEJAFOK_00958 748671.LCRIS_00831 1.43e-96 281.0 COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,3F7MQ@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF AGEJAFOK_00959 748671.LCRIS_00830 2.52e-300 822.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,3F4V1@33958|Lactobacillaceae 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin AGEJAFOK_00960 748671.LCRIS_00829 3.3e-315 860.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,3F413@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA AGEJAFOK_00961 748671.LCRIS_00828 3.14e-194 540.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,3F406@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 AGEJAFOK_00962 748671.LCRIS_00827 3.88e-264 723.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,3F4FW@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 AGEJAFOK_00963 748671.LCRIS_00826 0.0 905.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,3F49W@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M AGEJAFOK_00964 748671.LCRIS_00825 4.43e-224 618.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,3F3YP@33958|Lactobacillaceae 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 AGEJAFOK_00965 748671.LCRIS_00824 0.0 1350.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,3F47N@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase AGEJAFOK_00966 748671.LCRIS_00823 6.55e-72 217.0 COG4839@1|root,COG4839@2|Bacteria,1VCE5@1239|Firmicutes,4HM4W@91061|Bacilli,3F6KG@33958|Lactobacillaceae 91061|Bacilli D Cell division protein FtsL ftsL - - - - - - - - - - - DivIC AGEJAFOK_00967 748671.LCRIS_00822 1.49e-223 616.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,3F3MF@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 AGEJAFOK_00968 748671.LCRIS_00821 5.63e-102 295.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,3F6K3@33958|Lactobacillaceae 91061|Bacilli K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ AGEJAFOK_00969 748671.LCRIS_00820 1.02e-72 218.0 2A5PG@1|root,30UEB@2|Bacteria,1U6DY@1239|Firmicutes,4IG5S@91061|Bacilli,3F7PE@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3397) - - - - - - - - - - - - DUF3397 AGEJAFOK_00970 1423748.BALB01000001_gene50 1.4e-09 53.9 29GVY@1|root,303TQ@2|Bacteria,1TV7P@1239|Firmicutes,4I8MD@91061|Bacilli,3F8AT@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF4044) - - - - - - - - - - - - DUF4044 AGEJAFOK_00971 748671.LCRIS_00819 5.43e-122 348.0 29NQT@1|root,309NS@2|Bacteria,1U5E6@1239|Firmicutes,4IF5G@91061|Bacilli,3F5PM@33958|Lactobacillaceae 91061|Bacilli - - mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD AGEJAFOK_00972 748671.LCRIS_00818 8.27e-189 526.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,3F3MC@33958|Lactobacillaceae 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC AGEJAFOK_00973 748671.LCRIS_00817 8.26e-226 624.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F3ZV@33958|Lactobacillaceae 91061|Bacilli D cell shape determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl AGEJAFOK_00974 748671.LCRIS_00816 6.18e-150 421.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,3F5IM@33958|Lactobacillaceae 91061|Bacilli L DNA repair protein radC - - ko:K03630 - - - - ko00000 - - - RadC AGEJAFOK_00975 748671.LCRIS_00815 1.06e-162 455.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,3F56K@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 AGEJAFOK_00976 748671.LCRIS_00814 1.22e-306 836.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,3F498@33958|Lactobacillaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M AGEJAFOK_00977 748671.LCRIS_00813 0.0 1805.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,3F3RB@33958|Lactobacillaceae 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 AGEJAFOK_00978 1423758.BN55_07365 2.91e-67 209.0 2BSP6@1|root,32MRV@2|Bacteria,1TUTX@1239|Firmicutes,4IGKX@91061|Bacilli,3F8G1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00979 1423758.BN55_07370 3.02e-166 479.0 COG1106@1|root,COG1106@2|Bacteria,1UZQP@1239|Firmicutes,4IF7P@91061|Bacilli,3F5X4@33958|Lactobacillaceae 91061|Bacilli S AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K06926 - - - - ko00000 - - - AAA_21 AGEJAFOK_00980 748671.LCRIS_00808 0.0 1539.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase yoaB - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 AGEJAFOK_00981 748671.LCRIS_00802 9.25e-13 68.2 COG5464@1|root,COG5464@2|Bacteria,1V1A7@1239|Firmicutes,4HG0B@91061|Bacilli,3F655@33958|Lactobacillaceae 91061|Bacilli S PD-(D/E)XK nuclease family transposase - - - - - - - - - - - - PDDEXK_2 AGEJAFOK_00982 748671.LCRIS_00806 8.53e-59 181.0 29QEK@1|root,30BDY@2|Bacteria,1U7Z6@1239|Firmicutes,4IHWI@91061|Bacilli,3FACG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00983 748671.LCRIS_00805 3.33e-123 350.0 29X4B@1|root,30IT5@2|Bacteria,1TTS5@1239|Firmicutes,4I8EJ@91061|Bacilli,3F88E@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3990) - - - - - - - - - - - - DUF3990 AGEJAFOK_00984 748671.LCRIS_00804 4.08e-218 602.0 COG1216@1|root,COG1216@2|Bacteria,1UHWE@1239|Firmicutes,4ISA4@91061|Bacilli,3F3JX@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 2 family protein yfdH - - ko:K12999 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 AGEJAFOK_00985 748671.LCRIS_00803 1.06e-86 256.0 COG2246@1|root,COG2246@2|Bacteria,1VP71@1239|Firmicutes,4HSE0@91061|Bacilli,3F73E@33958|Lactobacillaceae 91061|Bacilli S GtrA-like protein - - - - - - - - - - - - GtrA AGEJAFOK_00986 748671.LCRIS_00802 3.97e-57 184.0 COG5464@1|root,COG5464@2|Bacteria,1V1A7@1239|Firmicutes,4HG0B@91061|Bacilli,3F655@33958|Lactobacillaceae 91061|Bacilli S PD-(D/E)XK nuclease family transposase - - - - - - - - - - - - PDDEXK_2 AGEJAFOK_00987 748671.LCRIS_00801 6.01e-153 431.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,3F41G@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 AGEJAFOK_00988 1423790.BN53_09240 2.1e-232 647.0 COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,4HF0C@91061|Bacilli,3F5RT@33958|Lactobacillaceae 91061|Bacilli K Putative ATP-dependent DNA helicase recG C-terminal - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4 AGEJAFOK_00989 748671.LCRIS_00785 3.48e-288 787.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,3F3N0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI AGEJAFOK_00990 748671.LCRIS_00784 4.1e-271 743.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,3F4CD@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 AGEJAFOK_00991 748671.LCRIS_00783 0.0 1035.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,3F47K@33958|Lactobacillaceae 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA AGEJAFOK_00992 748671.LCRIS_00782 3.07e-142 401.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,3F3P0@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 AGEJAFOK_00993 748671.LCRIS_00781 8.08e-110 315.0 COG5506@1|root,COG5506@2|Bacteria,1V8ID@1239|Firmicutes,4HJTQ@91061|Bacilli,3FCEV@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) - - - - - - - - - - - - DUF1694 AGEJAFOK_00994 748671.LCRIS_00780 5.98e-302 825.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3WF@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N AGEJAFOK_00995 748671.LCRIS_00779 1.35e-56 176.0 29P9A@1|root,30A7E@2|Bacteria,1U6AF@1239|Firmicutes,4IG1T@91061|Bacilli,3F7FU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_00996 748671.LCRIS_00778 9.45e-104 300.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,3F68T@33958|Lactobacillaceae 91061|Bacilli T universal stress protein uspA - - - - - - - - - - - Usp AGEJAFOK_00997 748671.LCRIS_00777 1.18e-275 755.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,3F4J4@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE AGEJAFOK_00998 748671.LCRIS_00776 5.13e-46 148.0 29FEW@1|root,302CK@2|Bacteria,1U6BQ@1239|Firmicutes,4IG3B@91061|Bacilli,3F7J3@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2969) - - - - - - - - - - - - DUF2969 AGEJAFOK_00999 748671.LCRIS_00775 1.59e-68 206.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,3F7H1@33958|Lactobacillaceae 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic AGEJAFOK_01000 748671.LCRIS_00774 4.81e-227 626.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F463@33958|Lactobacillaceae 91061|Bacilli D Cell shape determining protein MreB Mrl mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl AGEJAFOK_01001 748671.LCRIS_00773 2.54e-42 139.0 COG4836@1|root,COG4836@2|Bacteria,1U2FQ@1239|Firmicutes,4HNZX@91061|Bacilli,3F831@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1146) - - - - - - - - - - - - DUF1146 AGEJAFOK_01002 748671.LCRIS_00772 2.45e-93 273.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,3F6I6@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N AGEJAFOK_01003 748671.LCRIS_00771 0.0 888.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,3F3TF@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N AGEJAFOK_01004 748671.LCRIS_00770 1.04e-221 612.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,3F40E@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt AGEJAFOK_01005 748671.LCRIS_00769 0.0 972.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,3F3R4@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N AGEJAFOK_01006 748671.LCRIS_00768 3.24e-120 344.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,3F5TZ@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP AGEJAFOK_01007 525365.HMPREF0548_0197 2.57e-83 249.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,3F5M8@33958|Lactobacillaceae 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B AGEJAFOK_01008 1423748.BALB01000001_gene99 4.83e-37 125.0 COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,3F82A@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C AGEJAFOK_01009 748671.LCRIS_00765 1.01e-166 466.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,3F3RE@33958|Lactobacillaceae 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A AGEJAFOK_01010 748671.LCRIS_00764 5.28e-146 411.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,3F4M0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase AGEJAFOK_01011 748671.LCRIS_00763 1.36e-242 666.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,3F3T1@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC AGEJAFOK_01012 748671.LCRIS_00762 1.24e-198 550.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,3F460@33958|Lactobacillaceae 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS AGEJAFOK_01013 748671.LCRIS_00761 6.6e-237 654.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,3F3Q0@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 AGEJAFOK_01014 748671.LCRIS_00760 9.98e-146 410.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,3F4UE@33958|Lactobacillaceae 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK AGEJAFOK_01015 748671.LCRIS_00759 0.0 907.0 COG0770@1|root,COG0770@2|Bacteria,1TRG9@1239|Firmicutes,4HAMY@91061|Bacilli,3FBS5@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF1727) murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M AGEJAFOK_01018 748671.LCRIS_00758 3.94e-250 685.0 COG1680@1|root,COG1680@2|Bacteria,1TNZX@1239|Firmicutes,4IPJT@91061|Bacilli,3F3WZ@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase ampC - - - - - - - - - - - Beta-lactamase AGEJAFOK_01019 891391.LAC30SC_03770 4.63e-274 756.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 AGEJAFOK_01020 891391.LAC30SC_03765 0.0 876.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,3F3XK@33958|Lactobacillaceae 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI AGEJAFOK_01021 748671.LCRIS_00754 1.52e-136 387.0 COG4767@1|root,COG4767@2|Bacteria,1VK3A@1239|Firmicutes,4HPCD@91061|Bacilli,3F5EN@33958|Lactobacillaceae 91061|Bacilli V VanZ like family vanZ - - - - - - - - - - - VanZ AGEJAFOK_01022 748671.LCRIS_00753 0.0 1269.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase AGEJAFOK_01023 748671.LCRIS_00752 0.0 920.0 COG2972@1|root,COG5002@1|root,COG2972@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS6U@91061|Bacilli,3FBSR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA AGEJAFOK_01024 748671.LCRIS_00751 1.97e-170 476.0 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,3FC92@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C AGEJAFOK_01025 748671.LCRIS_00750 9.01e-90 263.0 COG5658@1|root,2ZY3R@2|Bacteria,1VKM4@1239|Firmicutes,4I0CM@91061|Bacilli,3F6IB@33958|Lactobacillaceae 91061|Bacilli S SdpI/YhfL protein family - - - - - - - - - - - - SdpI AGEJAFOK_01026 748671.LCRIS_00749 1.93e-242 664.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,3F40I@33958|Lactobacillaceae 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI AGEJAFOK_01027 748671.LCRIS_00748 1.72e-288 786.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 AGEJAFOK_01028 891391.LAC30SC_03725 3e-128 374.0 COG5434@1|root,COG5434@2|Bacteria,1TQXN@1239|Firmicutes,4HBHT@91061|Bacilli,3F4Y5@33958|Lactobacillaceae 91061|Bacilli M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 AGEJAFOK_01030 748671.LCRIS_00746 1.07e-281 770.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase AGEJAFOK_01031 748671.LCRIS_00745 2.42e-238 655.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,3F4CI@33958|Lactobacillaceae 91061|Bacilli L N-6 DNA Methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase AGEJAFOK_01032 748671.LCRIS_00744 3.69e-30 106.0 29PVR@1|root,30AU1@2|Bacteria,1U73U@1239|Firmicutes,4IGYA@91061|Bacilli,3F8XR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01033 748671.LCRIS_00743 1.94e-100 293.0 COG4940@1|root,COG4940@2|Bacteria,1U6NI@1239|Firmicutes,4IGFH@91061|Bacilli,3F87B@33958|Lactobacillaceae 91061|Bacilli U Putative Competence protein ComGF - - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF AGEJAFOK_01034 748671.LCRIS_00742 1.68e-55 173.0 2BS3U@1|root,32M4K@2|Bacteria,1U6G6@1239|Firmicutes,4IG89@91061|Bacilli,3F7UI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01035 748671.LCRIS_00741 8.19e-91 266.0 29ZCH@1|root,30MB3@2|Bacteria,1U645@1239|Firmicutes,4IFTR@91061|Bacilli,3F6ZT@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K02246 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl AGEJAFOK_01036 748671.LCRIS_00740 7.88e-63 193.0 COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli,3F7ZC@33958|Lactobacillaceae 91061|Bacilli U competence protein ComGC comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl AGEJAFOK_01037 748671.LCRIS_00739 1.72e-222 615.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,3F3S9@33958|Lactobacillaceae 91061|Bacilli NU type II secretion system comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF AGEJAFOK_01038 748671.LCRIS_00738 5.04e-231 636.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,3F4HY@33958|Lactobacillaceae 91061|Bacilli NU Type II IV secretion system protein comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE AGEJAFOK_01039 748671.LCRIS_00737 5.65e-171 477.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,3F4WF@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg AGEJAFOK_01040 748671.LCRIS_00736 2.33e-120 343.0 COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,4HMDE@91061|Bacilli,3F57S@33958|Lactobacillaceae 91061|Bacilli S VanZ like family - - - - - - - - - - - - VanZ AGEJAFOK_01041 748671.LCRIS_00735 3.9e-130 371.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,3F521@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding ylbE - - - - - - - - - - - NAD_binding_10 AGEJAFOK_01042 525365.HMPREF0548_0759 3.96e-37 124.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,3F7TS@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 AGEJAFOK_01044 525365.HMPREF0548_1705 1.08e-69 211.0 COG2801@1|root,COG2801@2|Bacteria,1W46R@1239|Firmicutes 1239|Firmicutes L Transposase and inactivated derivatives - - - - - - - - - - - - - AGEJAFOK_01045 1423748.BALB01000061_gene2095 1.01e-82 254.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut AGEJAFOK_01046 1423748.BALB01000029_gene1871 1.89e-47 152.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,3F7CY@33958|Lactobacillaceae 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 AGEJAFOK_01047 748671.LCRIS_00008 7.46e-108 312.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3F66N@33958|Lactobacillaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB AGEJAFOK_01048 748671.LCRIS_00007 1.93e-65 199.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HP6B@91061|Bacilli,3FCDH@33958|Lactobacillaceae 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 AGEJAFOK_01049 748671.LCRIS_00006 0.0 1578.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,3F3YM@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV AGEJAFOK_01050 748671.LCRIS_00005 0.0 1286.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,3F48M@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim AGEJAFOK_01051 748671.LCRIS_00004 5.14e-268 734.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N AGEJAFOK_01052 748671.LCRIS_00003 1.13e-48 154.0 COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,3F803@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein YaaA yaaA - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 AGEJAFOK_01053 748671.LCRIS_00002 1.05e-240 665.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,3F3ZQ@33958|Lactobacillaceae 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 AGEJAFOK_01054 748671.LCRIS_00001 1.92e-315 860.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,3F3YA@33958|Lactobacillaceae 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N AGEJAFOK_01055 1033837.WANG_1471 3.26e-23 88.6 COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,3F81W@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 AGEJAFOK_01056 748671.LCRIS_02023 1.87e-81 241.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,3F6GS@33958|Lactobacillaceae 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P AGEJAFOK_01057 748671.LCRIS_02022 5.58e-191 532.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,3F3SD@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP AGEJAFOK_01058 748671.LCRIS_02021 0.0 882.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,3F3WA@33958|Lactobacillaceae 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N AGEJAFOK_01059 748671.LCRIS_02020 0.0 1198.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,3F454@33958|Lactobacillaceae 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc AGEJAFOK_01060 748671.LCRIS_02019 0.0 1216.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family pox1 - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N AGEJAFOK_01061 748671.LCRIS_02018 5.38e-39 135.0 29NRE@1|root,30MH1@2|Bacteria,1U5EY@1239|Firmicutes,4IF6I@91061|Bacilli,3F5TJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01062 748671.LCRIS_02017 0.0 954.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,3F3S8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 AGEJAFOK_01063 748671.LCRIS_01239 0.0 953.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F46B@33958|Lactobacillaceae 91061|Bacilli V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran AGEJAFOK_01064 748671.LCRIS_01238 1.15e-64 211.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F46B@33958|Lactobacillaceae 91061|Bacilli V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran AGEJAFOK_01065 1423758.BN55_08840 2.14e-104 303.0 COG0645@1|root,COG0645@2|Bacteria,1UIME@1239|Firmicutes,4ISNB@91061|Bacilli,3F6E7@33958|Lactobacillaceae 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_33 AGEJAFOK_01066 1423767.BALU01000003_gene1088 6.97e-53 169.0 COG1051@1|root,COG1051@2|Bacteria,1V8PX@1239|Firmicutes,4HJXV@91061|Bacilli,3FC6S@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX AGEJAFOK_01067 748671.LCRIS_01039 4.87e-187 519.0 COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,4IRA8@91061|Bacilli,3F3UX@33958|Lactobacillaceae 91061|Bacilli F Phosphorylase superfamily - - - - - - - - - - - - PNP_UDP_1 AGEJAFOK_01068 748671.LCRIS_01040 5.92e-191 531.0 COG2746@1|root,COG2746@2|Bacteria,1V2QD@1239|Firmicutes,4HC3S@91061|Bacilli,3F635@33958|Lactobacillaceae 91061|Bacilli V Aminoglycoside 3-N-acetyltransferase - - 2.3.1.81 ko:K00662 - - - - ko00000,ko01000,ko01504 - - - Antibiotic_NAT AGEJAFOK_01069 97137.C821_01269 2.25e-125 370.0 COG0531@1|root,COG0531@2|Bacteria,1VTJD@1239|Firmicutes,4HTEM@91061|Bacilli,3FCAK@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yagE - - - - - - - - - - - AA_permease_2 AGEJAFOK_01070 97137.C821_01269 1.11e-41 148.0 COG0531@1|root,COG0531@2|Bacteria,1VTJD@1239|Firmicutes,4HTEM@91061|Bacilli,3FCAK@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yagE - - - - - - - - - - - AA_permease_2 AGEJAFOK_01071 748671.LCRIS_01044 2.75e-111 320.0 29NWN@1|root,309UR@2|Bacteria,1U5RD@1239|Firmicutes,4IFFJ@91061|Bacilli,3F6D7@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - SLAP AGEJAFOK_01072 748671.LCRIS_01045 4.7e-205 568.0 COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli,3FC4M@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 XK27_10395 - - - - - - - - - - - DUF2179,YitT_membrane AGEJAFOK_01073 748671.LCRIS_01046 1.72e-285 780.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,3F3VH@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 AGEJAFOK_01074 748671.LCRIS_01047 1.8e-143 406.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,3F578@33958|Lactobacillaceae 91061|Bacilli S protein, hemolysin III hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII AGEJAFOK_01075 748671.LCRIS_01048 8.83e-187 520.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,3FC90@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 degV3 - - - - - - - - - - - DegV AGEJAFOK_01076 748671.LCRIS_01049 9.85e-49 155.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,3F7ZP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like AGEJAFOK_01077 748671.LCRIS_01050 4.46e-89 262.0 COG0025@1|root,COG0025@2|Bacteria,1U8FU@1239|Firmicutes,4IIDP@91061|Bacilli,3FAXU@33958|Lactobacillaceae 91061|Bacilli P NhaP-type Na H and K H - - - - - - - - - - - - - AGEJAFOK_01078 748671.LCRIS_01051 3.21e-87 265.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaP4 - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger AGEJAFOK_01079 748671.LCRIS_01051 1.08e-95 288.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaP4 - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger AGEJAFOK_01080 748671.LCRIS_01052 2.15e-198 550.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,3F3MI@33958|Lactobacillaceae 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 AGEJAFOK_01081 748671.LCRIS_01053 1e-168 472.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,3F3JC@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII AGEJAFOK_01082 748671.LCRIS_01054 1.5e-195 543.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,3F41U@33958|Lactobacillaceae 91061|Bacilli LU DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A AGEJAFOK_01083 748671.LCRIS_01055 0.0 1365.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,3F3VS@33958|Lactobacillaceae 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom AGEJAFOK_01084 748671.LCRIS_01056 8.35e-315 857.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,3F3WW@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA AGEJAFOK_01085 525365.HMPREF0548_1030 2.09e-180 506.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4IQMI@91061|Bacilli,3FBHU@33958|Lactobacillaceae 91061|Bacilli D Phage integrase, N-terminal SAM-like domain xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase AGEJAFOK_01086 748671.LCRIS_01059 4.67e-116 333.0 COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,3F4HS@33958|Lactobacillaceae 91061|Bacilli O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome AGEJAFOK_01087 748671.LCRIS_01060 1.4e-313 857.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,3F3WB@33958|Lactobacillaceae 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small AGEJAFOK_01088 748671.LCRIS_01134 1.15e-204 566.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,3F40W@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV AGEJAFOK_01089 748671.LCRIS_01133 2.06e-88 260.0 29P8Y@1|root,30A72@2|Bacteria,1U6A0@1239|Firmicutes,4IG18@91061|Bacilli,3F7ER@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_24,MarR_2 AGEJAFOK_01090 748671.LCRIS_01132 0.0 1103.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,3F3PS@33958|Lactobacillaceae 91061|Bacilli K Fibronectin-binding protein FbpA - - - - - - - - - - - DUF814,FbpA AGEJAFOK_01091 748671.LCRIS_01131 0.0 2071.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB1 - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS AGEJAFOK_01092 748671.LCRIS_01130 2.91e-255 699.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase AGEJAFOK_01093 748671.LCRIS_01129 2.28e-221 610.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,3F3P6@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 AGEJAFOK_01094 748671.LCRIS_01128 1.1e-102 297.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,3F66R@33958|Lactobacillaceae 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 AGEJAFOK_01095 1423767.BALU01000003_gene1132 0.0 967.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,3F3U6@33958|Lactobacillaceae 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS AGEJAFOK_01096 748671.LCRIS_01125 1.61e-70 213.0 29PP8@1|root,30AME@2|Bacteria,1U6UZ@1239|Firmicutes,4IGNU@91061|Bacilli,3F8IU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01097 748671.LCRIS_01124 3.15e-132 384.0 COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,4HB6I@91061|Bacilli,3F5QB@33958|Lactobacillaceae 91061|Bacilli I Belongs to the phosphatidylserine decarboxylase family psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase AGEJAFOK_01098 575605.ACQN01000019_gene1182 5.56e-07 55.8 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - DUF285,GbpC,Gram_pos_anchor,YSIRK_signal AGEJAFOK_01099 748671.LCRIS_01122 8.99e-100 293.0 COG0790@1|root,COG0790@2|Bacteria,1UVA4@1239|Firmicutes,4IFX4@91061|Bacilli,3F77E@33958|Lactobacillaceae 91061|Bacilli S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 AGEJAFOK_01100 748671.LCRIS_01121 5.77e-127 362.0 COG4639@1|root,COG4639@2|Bacteria,1TQKR@1239|Firmicutes,4IF27@91061|Bacilli,3F5EC@33958|Lactobacillaceae 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_33 AGEJAFOK_01101 748671.LCRIS_01120 3.02e-232 640.0 2ACE2@1|root,311ZJ@2|Bacteria,1U5CK@1239|Firmicutes,4IF3R@91061|Bacilli,3F5IZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4767 AGEJAFOK_01102 748671.LCRIS_01119 8.53e-45 144.0 29PKY@1|root,30AJ4@2|Bacteria,1U6RQ@1239|Firmicutes,4IGJ5@91061|Bacilli,3F8DH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01103 748671.LCRIS_01118 6.75e-101 292.0 2BPEU@1|root,32I71@2|Bacteria,1UV7U@1239|Firmicutes,4IFZ5@91061|Bacilli,3F7AQ@33958|Lactobacillaceae 91061|Bacilli S HIRAN - - - - - - - - - - - - HIRAN AGEJAFOK_01104 557436.Lreu_1048 1.3e-62 211.0 COG0210@1|root,COG0210@2|Bacteria,1VFDH@1239|Firmicutes,4IQWT@91061|Bacilli 91061|Bacilli L DNA helicase - - - - - - - - - - - - AAA_19 AGEJAFOK_01105 557436.Lreu_1049 1.04e-144 434.0 COG3950@1|root,COG3950@2|Bacteria 2|Bacteria S AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K07459 - - - - ko00000 - - - AAA_15,AAA_21,AAA_23 AGEJAFOK_01106 1033837.WANG_1903 6.34e-66 200.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,3F6KC@33958|Lactobacillaceae 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 AGEJAFOK_01107 1423767.BALU01000004_gene1275 6.64e-146 411.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,3F45I@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 AGEJAFOK_01108 748671.LCRIS_00299 4.68e-138 391.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,3F3QD@33958|Lactobacillaceae 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 AGEJAFOK_01109 748671.LCRIS_00300 1.14e-63 194.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,3F6Z2@33958|Lactobacillaceae 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 AGEJAFOK_01110 748671.LCRIS_00301 3.3e-197 546.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,3F3XI@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C AGEJAFOK_01111 1423767.BALU01000004_gene1271 1.14e-62 191.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,3F6XP@33958|Lactobacillaceae 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 AGEJAFOK_01112 1423767.BALU01000004_gene1270 9.07e-73 219.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,3F6K6@33958|Lactobacillaceae 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 AGEJAFOK_01113 748671.LCRIS_00304 8.7e-157 440.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,3F3Q8@33958|Lactobacillaceae 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C AGEJAFOK_01114 1423748.BALB01000002_gene322 1.66e-100 291.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,3F653@33958|Lactobacillaceae 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 AGEJAFOK_01115 1033837.WANG_0004 1.45e-34 118.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,3F82Z@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 AGEJAFOK_01116 748671.LCRIS_00307 1.56e-55 173.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,3F7FX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 AGEJAFOK_01117 272621.LBA0301 1.04e-78 234.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,3F6GT@33958|Lactobacillaceae 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 AGEJAFOK_01118 748671.LCRIS_00309 3.03e-44 144.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3F6X5@33958|Lactobacillaceae 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 AGEJAFOK_01119 748671.LCRIS_00310 1.23e-123 352.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,3F3Q7@33958|Lactobacillaceae 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C AGEJAFOK_01120 1423748.BALB01000002_gene316 1e-39 131.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,3FB5M@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 AGEJAFOK_01121 748671.LCRIS_00312 7.94e-90 263.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,3F64E@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 AGEJAFOK_01122 748671.LCRIS_00313 7.18e-121 345.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,3F4G5@33958|Lactobacillaceae 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 AGEJAFOK_01123 748671.LCRIS_00314 4.84e-73 219.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,3F6KN@33958|Lactobacillaceae 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p AGEJAFOK_01124 748671.LCRIS_00315 3.73e-110 317.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,3F3VY@33958|Lactobacillaceae 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C AGEJAFOK_01125 748671.LCRIS_00316 2.22e-34 117.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,3F7ZU@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 AGEJAFOK_01126 748671.LCRIS_00317 2.86e-92 270.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,3F675@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A AGEJAFOK_01127 748671.LCRIS_00318 3.59e-301 822.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,3F4FV@33958|Lactobacillaceae 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY AGEJAFOK_01128 1423748.BALB01000002_gene308 3.7e-155 435.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,3F3KB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid AGEJAFOK_01129 1293597.BN147_06990 3.13e-46 148.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,3F7CW@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a AGEJAFOK_01130 1423748.BALB01000002_gene306 1.89e-21 83.6 COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,3F8TC@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 AGEJAFOK_01131 748671.LCRIS_00321 2.07e-73 220.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,3F6GN@33958|Lactobacillaceae 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 AGEJAFOK_01132 1033837.WANG_0019 3.82e-82 243.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,3F67D@33958|Lactobacillaceae 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 AGEJAFOK_01133 748671.LCRIS_00323 3.62e-218 602.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,3F3W6@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L AGEJAFOK_01134 748671.LCRIS_00324 1.29e-79 237.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,3F6GJ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 AGEJAFOK_01135 748671.LCRIS_00325 1.02e-198 551.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,3F3VD@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran AGEJAFOK_01136 748671.LCRIS_00326 5.5e-202 559.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,3F48E@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran AGEJAFOK_01137 748671.LCRIS_00327 6.51e-177 494.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,3F3UW@33958|Lactobacillaceae 91061|Bacilli U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ AGEJAFOK_01138 748671.LCRIS_00328 5.08e-193 535.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,3F4KC@33958|Lactobacillaceae 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 AGEJAFOK_01139 748671.LCRIS_00329 3.22e-103 298.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,3F696@33958|Lactobacillaceae 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 AGEJAFOK_01140 525365.HMPREF0548_2076 1.61e-84 249.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,3F656@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 AGEJAFOK_01141 891391.LAC30SC_01600 1.44e-234 647.0 COG0582@1|root,COG0582@2|Bacteria,1UH9G@1239|Firmicutes,4HCAS@91061|Bacilli,3F5XJ@33958|Lactobacillaceae 91061|Bacilli L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase AGEJAFOK_01142 945021.TEH_07770 4.65e-219 615.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,4B36Y@81852|Enterococcaceae 91061|Bacilli L Bifunctional protein - - - - - - - - - - - - GIIM,RVT_1 AGEJAFOK_01143 891391.LAC30SC_07850 6.1e-186 530.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 AGEJAFOK_01144 891391.LAC30SC_07850 9.92e-65 212.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 AGEJAFOK_01145 748671.LCRIS_01663 1.2e-220 611.0 29NMZ@1|root,309JX@2|Bacteria,1U58Z@1239|Firmicutes,4IF0A@91061|Bacilli,3F573@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - zf-ribbon_3 AGEJAFOK_01146 592010.GCWU000182_000841 1.86e-31 120.0 COG0454@1|root,COG0454@2|Bacteria,1W1HC@1239|Firmicutes,4HZZ6@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_7 AGEJAFOK_01148 748671.LCRIS_01664 0.0 1247.0 COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HBM6@91061|Bacilli,3FCCY@33958|Lactobacillaceae 91061|Bacilli S MMPL family ydgH - - ko:K06994 - - - - ko00000 - - - MMPL AGEJAFOK_01149 748671.LCRIS_01665 1.53e-127 363.0 COG1309@1|root,COG1309@2|Bacteria,1V1DM@1239|Firmicutes,4HG0Y@91061|Bacilli,3F5CS@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family yobS GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N,WHG AGEJAFOK_01150 748671.LCRIS_01666 1.89e-205 570.0 COG2367@1|root,COG2367@2|Bacteria,1U564@1239|Firmicutes,4IEXG@91061|Bacilli,3F4WE@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 AGEJAFOK_01151 748671.LCRIS_01667 1.4e-207 575.0 COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,4HAPC@91061|Bacilli,3FCA3@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein corA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - iYO844.BSU08000 CorA AGEJAFOK_01152 748671.LCRIS_01668 1.23e-309 844.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HEKH@91061|Bacilli,3F4P5@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 AGEJAFOK_01153 748671.LCRIS_01669 0.0 885.0 COG0595@1|root,COG0595@2|Bacteria,1UDEF@1239|Firmicutes,4HIN2@91061|Bacilli,3F4WJ@33958|Lactobacillaceae 91061|Bacilli S Zn-dependent metallo-hydrolase RNA specificity domain - - - - - - - - - - - - Lactamase_B_2,RMMBL AGEJAFOK_01154 748671.LCRIS_01670 5.62e-187 520.0 COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBK1@91061|Bacilli,3FC8G@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 AGEJAFOK_01155 748671.LCRIS_01671 1.64e-202 561.0 COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HCD0@91061|Bacilli,3F464@33958|Lactobacillaceae 91061|Bacilli P ABC-type sugar transport systems, permease components - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 AGEJAFOK_01156 748671.LCRIS_01672 5.26e-259 710.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HBKK@91061|Bacilli,3FC3J@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities malK - - ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.38 - - ABC_tran,TOBE_2 AGEJAFOK_01157 748671.LCRIS_01673 0.0 972.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD1 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 AGEJAFOK_01158 748671.LCRIS_01674 7.24e-204 564.0 COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli,3F3Y8@33958|Lactobacillaceae 91061|Bacilli F DNA RNA non-specific endonuclease endA - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 AGEJAFOK_01159 748671.LCRIS_01675 1.29e-230 634.0 COG2176@1|root,COG2176@2|Bacteria,1TRS5@1239|Firmicutes,4HFJA@91061|Bacilli,3F546@33958|Lactobacillaceae 91061|Bacilli L EXOIII - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - BRCT,RNase_T AGEJAFOK_01160 748671.LCRIS_01676 5.11e-203 561.0 COG0846@1|root,COG0846@2|Bacteria,1V192@1239|Firmicutes,4IQTP@91061|Bacilli,3F52D@33958|Lactobacillaceae 91061|Bacilli K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - - - - - - - - - - SIR2 AGEJAFOK_01161 748671.LCRIS_01677 2.23e-150 423.0 COG2323@1|root,COG2323@2|Bacteria,1TPNF@1239|Firmicutes,4HF15@91061|Bacilli,3F4F3@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF421) yviA - - - - - - - - - - - DUF421 AGEJAFOK_01162 748671.LCRIS_01678 2.94e-74 224.0 2C9NT@1|root,32ZGB@2|Bacteria,1VG8C@1239|Firmicutes,4HN0V@91061|Bacilli,3F749@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3290) - - - - - - - - - - - - DUF3290 AGEJAFOK_01163 1230342.CTM_04943 1.91e-90 283.0 COG2801@1|root,COG2801@2|Bacteria,1TT8V@1239|Firmicutes,24BFH@186801|Clostridia,36I9T@31979|Clostridiaceae 186801|Clostridia L PFAM Integrase catalytic - - - - - - - - - - - - HTH_28,rve AGEJAFOK_01164 748671.LCRIS_01377 2.28e-76 230.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F587@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC AGEJAFOK_01165 748671.LCRIS_01025 9.44e-117 338.0 COG1670@1|root,COG1670@2|Bacteria,1V3W1@1239|Firmicutes,4HH6A@91061|Bacilli,3F6G6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yokL3 - - - - - - - - - - - Acetyltransf_3 AGEJAFOK_01166 748671.LCRIS_01023 0.0 977.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HIAU@91061|Bacilli,3F3JJ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran AGEJAFOK_01167 748671.LCRIS_01022 0.0 983.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N AGEJAFOK_01168 748671.LCRIS_01021 3.52e-293 801.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,3F3ND@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat protein XK27_05225 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 AGEJAFOK_01169 748671.LCRIS_01020 1.17e-56 176.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,3F6YN@33958|Lactobacillaceae 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding AGEJAFOK_01170 748671.LCRIS_01019 1.34e-314 857.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,3F4V0@33958|Lactobacillaceae 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 AGEJAFOK_01171 748671.LCRIS_01018 1.4e-281 770.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,3F4DQ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 AGEJAFOK_01172 748671.LCRIS_01017 1.96e-148 419.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,3F3W4@33958|Lactobacillaceae 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin AGEJAFOK_01173 748671.LCRIS_01016 1.13e-41 143.0 COG1388@1|root,COG1388@2|Bacteria,1W2PN@1239|Firmicutes,4I0F8@91061|Bacilli,3F6G9@33958|Lactobacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM AGEJAFOK_01174 748671.LCRIS_01015 8.49e-146 412.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,3F4HD@33958|Lactobacillaceae 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt AGEJAFOK_01175 748671.LCRIS_01014 4.65e-168 469.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,3F402@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 AGEJAFOK_01176 748671.LCRIS_01013 7.57e-135 382.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,3F5RN@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB AGEJAFOK_01177 748671.LCRIS_01012 1.81e-169 474.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,3F4FS@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA AGEJAFOK_01178 748671.LCRIS_01011 1.13e-81 241.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,3F7QC@33958|Lactobacillaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1,Acetyltransf_10 AGEJAFOK_01179 748671.LCRIS_01010 6.74e-213 588.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae 91061|Bacilli D recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase AGEJAFOK_01180 748671.LCRIS_01009 1.21e-213 590.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,3F44W@33958|Lactobacillaceae 91061|Bacilli S S1 domain yitL - - ko:K00243 - - - - ko00000 - - - S1_2 AGEJAFOK_01181 748671.LCRIS_01008 0.0 1137.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,3F3JU@33958|Lactobacillaceae 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C AGEJAFOK_01182 748671.LCRIS_01007 5.46e-233 640.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,3F4CC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK AGEJAFOK_01183 748671.LCRIS_00866 2.56e-291 798.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,3F40B@33958|Lactobacillaceae 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N AGEJAFOK_01184 748671.LCRIS_00867 3.04e-297 811.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,3F41K@33958|Lactobacillaceae 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX AGEJAFOK_01185 748671.LCRIS_00868 1.59e-136 386.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,3F44G@33958|Lactobacillaceae 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 AGEJAFOK_01186 525365.HMPREF0548_0903 2.58e-48 166.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HA0N@91061|Bacilli,3F4J0@33958|Lactobacillaceae 91061|Bacilli E Amino Acid potE - - - - - - - - - - - AA_permease_2 AGEJAFOK_01187 891391.LAC30SC_04260 1.27e-220 617.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HA0N@91061|Bacilli,3F4J0@33958|Lactobacillaceae 91061|Bacilli E Amino Acid potE - - - - - - - - - - - AA_permease_2 AGEJAFOK_01188 748671.LCRIS_00872 6.25e-246 674.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,3F4F7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase AGEJAFOK_01189 748671.LCRIS_00873 0.0 889.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 AGEJAFOK_01190 748671.LCRIS_00874 1.39e-312 852.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,3F3VJ@33958|Lactobacillaceae 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC AGEJAFOK_01191 748671.LCRIS_00875 8.62e-105 309.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,3F3U0@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep AGEJAFOK_01192 748671.LCRIS_00876 3.29e-280 765.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,3F419@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 AGEJAFOK_01193 748671.LCRIS_00877 3.66e-225 620.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,3F4UH@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS AGEJAFOK_01194 748671.LCRIS_00878 6.89e-185 514.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,3F3MA@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N AGEJAFOK_01195 748671.LCRIS_00879 9.03e-277 757.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspC - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 AGEJAFOK_01196 748671.LCRIS_00880 2.48e-252 692.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,3F4S9@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC AGEJAFOK_01197 748671.LCRIS_00881 4.2e-249 684.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX1 - - - - - - - - - - - Beta-lactamase,SLH AGEJAFOK_01198 748671.LCRIS_00882 0.0 1028.0 COG2267@1|root,COG2267@2|Bacteria,1UHVZ@1239|Firmicutes,4ISGG@91061|Bacilli,3F5G1@33958|Lactobacillaceae 91061|Bacilli I Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974,DUF308 AGEJAFOK_01199 748671.LCRIS_00865 5.76e-287 783.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,3F3ZP@33958|Lactobacillaceae 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 AGEJAFOK_01200 748671.LCRIS_00864 5.43e-191 531.0 2CC00@1|root,30489@2|Bacteria,1TW9B@1239|Firmicutes,4I50I@91061|Bacilli,3F52A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - TPR_19 AGEJAFOK_01201 748671.LCRIS_00863 0.0 1122.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3U9@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL AGEJAFOK_01202 748671.LCRIS_00862 7.11e-57 176.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,3F7DV@33958|Lactobacillaceae 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 AGEJAFOK_01203 748671.LCRIS_00861 3.64e-46 149.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,3F7D8@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p AGEJAFOK_01204 748671.LCRIS_00860 2.57e-226 624.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,3F3TP@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta AGEJAFOK_01205 748671.LCRIS_00859 0.0 1472.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,3F3VT@33958|Lactobacillaceae 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B AGEJAFOK_01206 748671.LCRIS_00858 2.7e-126 363.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,3F7NP@33958|Lactobacillaceae 91061|Bacilli L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB AGEJAFOK_01207 748671.LCRIS_00857 1.42e-244 672.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,3F4KY@33958|Lactobacillaceae 91061|Bacilli T Belongs to the peptidase S16 family lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 AGEJAFOK_01208 748671.LCRIS_00856 7.07e-107 308.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,3FCD3@33958|Lactobacillaceae 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like AGEJAFOK_01209 748671.LCRIS_00855 5.21e-126 358.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,3F505@33958|Lactobacillaceae 91061|Bacilli L RNA methyltransferase, RsmD family rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 AGEJAFOK_01210 748671.LCRIS_00854 9.94e-71 213.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,3F70V@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2129) ylbG - - - - - - - - - - - DUF2129 AGEJAFOK_01211 748671.LCRIS_00853 3.91e-268 736.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,3F4IK@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE AGEJAFOK_01212 748671.LCRIS_00852 0.0 1209.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,3F3UK@33958|Lactobacillaceae 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 AGEJAFOK_01213 748671.LCRIS_00851 2.79e-131 372.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,3F3YH@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase AGEJAFOK_01214 1423767.BALU01000002_gene1703 5.22e-45 145.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,3F807@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 AGEJAFOK_01215 748671.LCRIS_00848 0.0 1103.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3TT@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL AGEJAFOK_01216 748671.LCRIS_00368 2.12e-86 256.0 COG3039@1|root,COG3039@2|Bacteria,1UZVA@1239|Firmicutes,4HH09@91061|Bacilli,3F4KP@33958|Lactobacillaceae 91061|Bacilli L An automated process has identified a potential problem with this gene model - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_3 AGEJAFOK_01217 1423754.BALY01000052_gene1836 1.3e-162 483.0 2DKJ8@1|root,309P7@2|Bacteria,1U5FB@1239|Firmicutes,4IF6X@91061|Bacilli,3F5UP@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP AGEJAFOK_01219 748671.LCRIS_00183 1.47e-286 783.0 COG1705@1|root,COG1705@2|Bacteria,1TVPT@1239|Firmicutes,4HC0X@91061|Bacilli,3F4I7@33958|Lactobacillaceae 91061|Bacilli NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - - - - - - - - - - Glucosaminidase,SLAP AGEJAFOK_01220 748671.LCRIS_00184 1.14e-235 651.0 COG5632@1|root,COG5632@2|Bacteria,1V3MY@1239|Firmicutes,4HBWG@91061|Bacilli,3F4BU@33958|Lactobacillaceae 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase - - 3.2.1.96,3.5.1.28 ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 - R04112 RC00064,RC00141 ko00000,ko00001,ko01000 - GH73 - Amidase_2,Glucosaminidase,SH3_8,SLAP AGEJAFOK_01221 748671.LCRIS_00185 0.0 1093.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,3F4AZ@33958|Lactobacillaceae 91061|Bacilli P TrkA C-terminal domain protein yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N AGEJAFOK_01222 748671.LCRIS_00186 2.47e-138 392.0 COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,3F46I@33958|Lactobacillaceae 91061|Bacilli O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 AGEJAFOK_01223 748671.LCRIS_00187 1.68e-207 576.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HV6B@91061|Bacilli,3FCE9@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C AGEJAFOK_01224 748671.LCRIS_00188 1.98e-168 473.0 29NPN@1|root,309MJ@2|Bacteria,1U5C8@1239|Firmicutes,4IF3G@91061|Bacilli,3F5HZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01225 748671.LCRIS_00189 1.72e-149 424.0 2E0R1@1|root,32W9E@2|Bacteria,1U59S@1239|Firmicutes,4IF1B@91061|Bacilli,3F5B0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01226 748671.LCRIS_00190 4.51e-171 476.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,3F3SK@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 AGEJAFOK_01227 748671.LCRIS_00191 5.18e-128 364.0 COG2017@1|root,COG2017@2|Bacteria,1U5EB@1239|Firmicutes,4IF5R@91061|Bacilli,3F5Q4@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase - - - - - - - - - - - - Aldose_epim AGEJAFOK_01228 748671.LCRIS_00192 2.92e-258 708.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr AGEJAFOK_01229 748671.LCRIS_00193 1.03e-145 410.0 COG0344@1|root,COG0344@2|Bacteria,1VAFC@1239|Firmicutes,4HMJZ@91061|Bacilli,3F5HQ@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY1 - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf AGEJAFOK_01230 748671.LCRIS_00194 0.0 1859.0 COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,4HBY6@91061|Bacilli,3F3NY@33958|Lactobacillaceae 91061|Bacilli M Sulfatase XK27_08315 - - - - - - - - - - - Sulfatase AGEJAFOK_01231 748671.LCRIS_01240 5.73e-153 440.0 29QEJ@1|root,30BDX@2|Bacteria,1U7Z5@1239|Firmicutes,4IHWH@91061|Bacilli,3FACF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01232 748671.LCRIS_01143 5.03e-76 227.0 COG1396@1|root,COG1396@2|Bacteria,1UUUD@1239|Firmicutes,4I3X4@91061|Bacilli,3F8QF@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3,HTH_31 AGEJAFOK_01233 748671.LCRIS_01144 1.17e-144 407.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,3F3TI@33958|Lactobacillaceae 91061|Bacilli G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase AGEJAFOK_01234 748671.LCRIS_01145 1.05e-221 611.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,3F3PJ@33958|Lactobacillaceae 91061|Bacilli C inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 AGEJAFOK_01235 748671.LCRIS_01146 1.11e-234 645.0 COG0583@1|root,COG0583@2|Bacteria,1UYS5@1239|Firmicutes,4HF07@91061|Bacilli,3F48B@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate AGEJAFOK_01236 748671.LCRIS_01147 0.0 1586.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,3F3MJ@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV AGEJAFOK_01237 748671.LCRIS_01148 0.0 1234.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,3F430@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim AGEJAFOK_01238 748671.LCRIS_01149 9.39e-141 398.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,3F543@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf AGEJAFOK_01239 748671.LCRIS_01150 0.0 1989.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,3F52K@33958|Lactobacillaceae 91061|Bacilli KL domain protein snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM AGEJAFOK_01240 748671.LCRIS_01152 1.73e-48 154.0 29PHT@1|root,30AFY@2|Bacteria,1U6M0@1239|Firmicutes,4IGDT@91061|Bacilli,3F84R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - RepA_N AGEJAFOK_01241 1423748.BALB01000020_gene1596 1.24e-08 53.1 29PHT@1|root,30AFY@2|Bacteria,1U6M0@1239|Firmicutes,4IGDT@91061|Bacilli,3F84R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - RepA_N AGEJAFOK_01242 748671.LCRIS_01153 4.83e-136 384.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli,3F41F@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family pncA - - - - - - - - - - - Isochorismatase AGEJAFOK_01243 748671.LCRIS_01154 1.51e-159 449.0 arCOG05209@1|root,31PIN@2|Bacteria,1V5G2@1239|Firmicutes,4HIRV@91061|Bacilli,3F6X9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01246 748671.LCRIS_01157 4.13e-83 245.0 29P12@1|root,309Z7@2|Bacteria,1U5Z5@1239|Firmicutes,4IFN5@91061|Bacilli,3F6QZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01247 748671.LCRIS_01158 3.56e-47 151.0 2CKSK@1|root,30A8J@2|Bacteria,1U6BY@1239|Firmicutes,4IG3K@91061|Bacilli,3F7JR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01248 748671.LCRIS_01994 9.69e-292 799.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease AGEJAFOK_01249 748671.LCRIS_01993 2.56e-179 500.0 COG0561@1|root,COG0561@2|Bacteria,1TSGF@1239|Firmicutes,4HHWU@91061|Bacilli,3F57T@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 AGEJAFOK_01250 748671.LCRIS_01992 6.64e-94 275.0 29NX2@1|root,309V6@2|Bacteria,1U5S0@1239|Firmicutes,4IFGA@91061|Bacilli,3F6ET@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01251 1423748.BALB01000021_gene1662 1.06e-159 447.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F488@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase dgk2 - 2.7.1.76 ko:K10353 ko00230,ko01100,map00230,map01100 - R02089 RC00002,RC00017 ko00000,ko00001,ko01000 - - - dNK AGEJAFOK_01252 748671.LCRIS_01990 9.85e-154 431.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F488@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase dak - 2.7.1.76 ko:K10353 ko00230,ko01100,map00230,map01100 - R02089 RC00002,RC00017 ko00000,ko00001,ko01000 - - - dNK AGEJAFOK_01253 748671.LCRIS_01989 1.15e-173 484.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,3F3NR@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso AGEJAFOK_01254 748671.LCRIS_01988 3.08e-205 566.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HU74@91061|Bacilli,3FB4R@33958|Lactobacillaceae 91061|Bacilli S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red AGEJAFOK_01255 748671.LCRIS_01987 3.63e-221 610.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli,3F4AJ@33958|Lactobacillaceae 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 AGEJAFOK_01256 748671.LCRIS_01986 8.8e-262 719.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli,3F59X@33958|Lactobacillaceae 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family mglC - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 AGEJAFOK_01257 748671.LCRIS_01985 0.0 972.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,3F50N@33958|Lactobacillaceae 91061|Bacilli S ABC transporter mglA - 3.6.3.17 ko:K02056,ko:K06400 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran AGEJAFOK_01258 748671.LCRIS_01984 4.57e-232 640.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,3F3MZ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter substrate-binding protein PnrA-like tcsA - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp AGEJAFOK_01259 748671.LCRIS_01983 1.97e-255 701.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,3F3MZ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter substrate-binding protein PnrA-like tcsA - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp AGEJAFOK_01260 748671.LCRIS_01982 5.9e-130 370.0 COG4684@1|root,COG4684@2|Bacteria,1V2ZW@1239|Firmicutes,4IR4I@91061|Bacilli,3FBM9@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt AGEJAFOK_01261 748671.LCRIS_01981 0.0 1792.0 COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli,3F4BB@33958|Lactobacillaceae 91061|Bacilli H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase AGEJAFOK_01262 748671.LCRIS_01980 0.0 1463.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD AGEJAFOK_01263 748671.LCRIS_01979 5.14e-248 682.0 COG1434@1|root,COG1434@2|Bacteria,1V8H4@1239|Firmicutes,4HI4B@91061|Bacilli,3FC81@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 AGEJAFOK_01264 748671.LCRIS_01978 3.43e-155 435.0 COG1266@1|root,COG1266@2|Bacteria,1VFRX@1239|Firmicutes,4HRQQ@91061|Bacilli,3F4Q0@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi AGEJAFOK_01265 525365.HMPREF0548_1399 1.49e-141 406.0 COG1396@1|root,COG1396@2|Bacteria,1VD8E@1239|Firmicutes,4HMD2@91061|Bacilli,3F61C@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator ywdE - - ko:K20375 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 AGEJAFOK_01266 525365.HMPREF0548_1400 3.62e-202 571.0 COG0477@1|root,COG0477@2|Bacteria,1UI8U@1239|Firmicutes,4ISG9@91061|Bacilli,3FBSV@33958|Lactobacillaceae 91061|Bacilli EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 AGEJAFOK_01267 748671.LCRIS_01977 1.05e-67 206.0 2BZTJ@1|root,30A2T@2|Bacteria,1U644@1239|Firmicutes,4IFTP@91061|Bacilli,3F6ZQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01268 748671.LCRIS_01976 1.91e-200 555.0 COG1396@1|root,COG1396@2|Bacteria,1U54X@1239|Firmicutes,4IEW2@91061|Bacilli,3F4P7@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins mutR - - - - - - - - - - - HTH_3 AGEJAFOK_01269 748671.LCRIS_01974 0.0 949.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HIAU@91061|Bacilli,3F3JJ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran AGEJAFOK_01270 405566.lhv_2907 1.68e-55 173.0 COG4115@1|root,COG4115@2|Bacteria,1VEN0@1239|Firmicutes,4HRVW@91061|Bacilli,3F80N@33958|Lactobacillaceae 91061|Bacilli S YoeB-like toxin of bacterial type II toxin-antitoxin system yoeB - - ko:K19158 - - - - ko00000,ko01000,ko02048 - - - YoeB_toxin AGEJAFOK_01271 1423748.BALB01000014_gene1354 2.49e-63 194.0 COG2161@1|root,COG2161@2|Bacteria,1U6UC@1239|Firmicutes,4IGN6@91061|Bacilli,3F8I1@33958|Lactobacillaceae 91061|Bacilli D Antitoxin component of a toxin-antitoxin (TA) module - - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox AGEJAFOK_01272 748671.LCRIS_01973 5.71e-263 722.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HP0X@91061|Bacilli,3FCEG@33958|Lactobacillaceae 91061|Bacilli P Sodium/hydrogen exchanger family napA - - - - - - - - - - - Na_H_Exchanger,Usp AGEJAFOK_01273 748671.LCRIS_01972 0.0 1156.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4JI@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - - - - - - - - - - - E1-E2_ATPase,Hydrolase AGEJAFOK_01274 748671.LCRIS_01971 3.41e-107 309.0 COG0517@1|root,COG0517@2|Bacteria,1V9HN@1239|Firmicutes,4HH3X@91061|Bacilli,3F678@33958|Lactobacillaceae 91061|Bacilli S (CBS) domain ykuL - - - - - - - - - - - CBS AGEJAFOK_01275 748671.LCRIS_01970 5.11e-265 726.0 COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,4HITC@91061|Bacilli,3F50M@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - AGEJAFOK_01276 748671.LCRIS_01969 1.42e-58 181.0 29P6X@1|root,30A50@2|Bacteria,1U67F@1239|Firmicutes,4IFXY@91061|Bacilli,3F78Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01277 748671.LCRIS_01968 9.18e-27 97.8 2DKQV@1|root,30ADX@2|Bacteria,1U6IK@1239|Firmicutes,4IGAZ@91061|Bacilli,3F7ZM@33958|Lactobacillaceae 91061|Bacilli S D-Ala-teichoic acid biosynthesis protein - - - - - - - - - - - - DUF3687 AGEJAFOK_01278 748671.LCRIS_01967 0.0 996.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,3F49R@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C AGEJAFOK_01279 748671.LCRIS_01966 3.08e-306 833.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,3F4KK@33958|Lactobacillaceae 91061|Bacilli M MBOAT, membrane-bound O-acyltransferase family dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT AGEJAFOK_01280 272621.LBA1924 4.98e-48 153.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,3F7Q1@33958|Lactobacillaceae 91061|Bacilli J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding AGEJAFOK_01281 748671.LCRIS_01964 9.71e-316 859.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,3F3WE@33958|Lactobacillaceae 91061|Bacilli M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD AGEJAFOK_01282 748671.LCRIS_01963 1.97e-227 626.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX2 - - - - - - - - - - - Beta-lactamase AGEJAFOK_01283 748671.LCRIS_01962 2.5e-172 480.0 COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,4HPG8@91061|Bacilli,3FBKG@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF975) - - - - - - - - - - - - DUF975 AGEJAFOK_01284 748671.LCRIS_01961 1.34e-183 515.0 COG3757@1|root,COG3757@2|Bacteria,1VF8D@1239|Firmicutes,4HX0U@91061|Bacilli,3F4U9@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 lysA2 - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,LysM,SH3_5,SLAP AGEJAFOK_01285 748671.LCRIS_01960 0.0 998.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,3F404@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C AGEJAFOK_01286 748671.LCRIS_01959 1.96e-49 157.0 2C9N2@1|root,30A73@2|Bacteria,1U6A1@1239|Firmicutes,4IG19@91061|Bacilli,3F7ES@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01287 748671.LCRIS_01958 0.0 1598.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,3F4HF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease ylbB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD AGEJAFOK_01288 748671.LCRIS_01957 1.68e-161 452.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,3F3YU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AGEJAFOK_01289 748671.LCRIS_01956 3.09e-304 830.0 COG1455@1|root,COG1455@2|Bacteria,1V5SI@1239|Firmicutes,4HJTK@91061|Bacilli,3F3Z5@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts13C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC AGEJAFOK_01290 748671.LCRIS_01955 7.86e-212 585.0 COG4814@1|root,COG4814@2|Bacteria,1V8NG@1239|Firmicutes,4HJ22@91061|Bacilli,3F41V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 AGEJAFOK_01291 748671.LCRIS_01954 0.0 1181.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F5GX@33958|Lactobacillaceae 91061|Bacilli O AAA domain (Cdc48 subfamily) clpE - - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR AGEJAFOK_01292 748671.LCRIS_01953 5.08e-149 419.0 COG0681@1|root,COG0681@2|Bacteria,1TRAV@1239|Firmicutes,4HCTU@91061|Bacilli,3FBKX@33958|Lactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family sipS3 - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 AGEJAFOK_01293 748671.LCRIS_01952 2.58e-310 847.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease aapA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease AGEJAFOK_01294 748671.LCRIS_01951 5.27e-314 857.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yifK - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease AGEJAFOK_01295 748671.LCRIS_01950 6.36e-173 488.0 COG1672@1|root,COG1672@2|Bacteria,1V0EH@1239|Firmicutes,4HXBI@91061|Bacilli,3F4KW@33958|Lactobacillaceae 91061|Bacilli S PFAM Archaeal ATPase - - - - - - - - - - - - ATPase_2 AGEJAFOK_01296 748671.LCRIS_01948 1.95e-221 610.0 COG1403@1|root,COG1403@2|Bacteria,1VM1P@1239|Firmicutes,4HSBX@91061|Bacilli 91061|Bacilli V HNH endonuclease - - - - - - - - - - - - - AGEJAFOK_01298 748671.LCRIS_01946 6.65e-179 497.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,3F4PK@33958|Lactobacillaceae 91061|Bacilli S peptidase C26 puuD - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 AGEJAFOK_01299 748671.LCRIS_01945 6.45e-291 799.0 COG0531@1|root,COG0531@2|Bacteria,1UZNT@1239|Firmicutes,4HFMI@91061|Bacilli,3F3SX@33958|Lactobacillaceae 91061|Bacilli E amino acid - - - - - - - - - - - - AA_permease,AA_permease_2 AGEJAFOK_01300 748671.LCRIS_01935 5.12e-242 665.0 COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,4HAEC@91061|Bacilli,3F40A@33958|Lactobacillaceae 91061|Bacilli F aspartate--ammonia ligase asnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 - R00483 RC00010 ko00000,ko00001,ko01000 - - - AsnA AGEJAFOK_01301 748671.LCRIS_01934 1.84e-263 720.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4HAHJ@91061|Bacilli,3FB4D@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) - - 4.2.1.126 ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - DUF871 AGEJAFOK_01304 748671.LCRIS_01933 1.35e-238 655.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,3F45K@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH AGEJAFOK_01305 748671.LCRIS_01932 0.0 867.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,3F3RQ@33958|Lactobacillaceae 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt AGEJAFOK_01306 748671.LCRIS_01931 7.13e-313 852.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,3F48P@33958|Lactobacillaceae 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 AGEJAFOK_01307 1154757.Q5C_00855 9.13e-157 455.0 COG3547@1|root,COG3547@2|Bacteria,1TRSB@1239|Firmicutes,4HDPK@91061|Bacilli 91061|Bacilli L PFAM transposase IS116 IS110 IS902 - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 AGEJAFOK_01308 748671.LCRIS_00018 4.07e-214 590.0 COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli,3F3K8@33958|Lactobacillaceae 91061|Bacilli GK ROK family scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK AGEJAFOK_01309 748671.LCRIS_00019 3.81e-18 77.0 29PGN@1|root,30AET@2|Bacteria,1U6JR@1239|Firmicutes,4IGC8@91061|Bacilli,3F81J@33958|Lactobacillaceae 91061|Bacilli S CsbD-like - - - - - - - - - - - - CsbD AGEJAFOK_01310 748671.LCRIS_00020 2.26e-31 112.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc AGEJAFOK_01311 1033837.WANG_1078 3.22e-121 357.0 COG0738@1|root,COG0738@2|Bacteria 2|Bacteria G Major facilitator superfamily ydiM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1 AGEJAFOK_01312 748671.LCRIS_01486 2.9e-254 697.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,3F4NT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d AGEJAFOK_01313 748671.LCRIS_01485 0.0 1577.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,3F3V3@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind AGEJAFOK_01314 748671.LCRIS_01484 1.72e-92 272.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,3F4ZF@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N AGEJAFOK_01315 748671.LCRIS_01483 8.21e-215 593.0 COG0039@1|root,COG0039@2|Bacteria,1TQIV@1239|Firmicutes,4IQTH@91061|Bacilli,3FBIV@33958|Lactobacillaceae 91061|Bacilli C lactate/malate dehydrogenase, alpha/beta C-terminal domain ldh3 - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N AGEJAFOK_01316 748671.LCRIS_01482 5.5e-203 561.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 AGEJAFOK_01317 748671.LCRIS_01481 1.8e-34 117.0 29Q02@1|root,31VTI@2|Bacteria,1U6SE@1239|Firmicutes,4IGJY@91061|Bacilli,3F8EM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01318 748671.LCRIS_01480 0.0 1086.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,3F3XB@33958|Lactobacillaceae 91061|Bacilli Q Multicopper oxidase sufI - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 AGEJAFOK_01319 748671.LCRIS_01479 1.76e-193 536.0 COG0561@1|root,COG0561@2|Bacteria,1UYC4@1239|Firmicutes,4HGTM@91061|Bacilli,3F5R1@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 AGEJAFOK_01320 748671.LCRIS_01478 0.0 1090.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F5SJ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AGEJAFOK_01321 748671.LCRIS_01477 2.77e-292 797.0 COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,4HDKW@91061|Bacilli,3F4D3@33958|Lactobacillaceae 91061|Bacilli Q Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 AGEJAFOK_01322 748671.LCRIS_01476 5.84e-312 849.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HE6F@91061|Bacilli,3F5DP@33958|Lactobacillaceae 91061|Bacilli S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 AGEJAFOK_01323 748671.LCRIS_01475 1.3e-175 491.0 arCOG09719@1|root,2Z7NA@2|Bacteria,1TSE4@1239|Firmicutes,4HE46@91061|Bacilli,3F5Z4@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3100) - - - - - - - - - - - - DUF3100 AGEJAFOK_01324 748671.LCRIS_01474 2.04e-60 188.0 2B1UF@1|root,31UAF@2|Bacteria,1V4WF@1239|Firmicutes,4HI2Y@91061|Bacilli,3F5V0@33958|Lactobacillaceae 91061|Bacilli S An automated process has identified a potential problem with this gene model - - - - - - - - - - - - - AGEJAFOK_01325 748671.LCRIS_01471 1.29e-164 462.0 29Q4Q@1|root,30B3F@2|Bacteria,1U7GR@1239|Firmicutes,4IHD4@91061|Bacilli,3F9N4@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP AGEJAFOK_01326 1423790.BN53_01125 4.34e-64 206.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,3F4TJ@33958|Lactobacillaceae 91061|Bacilli L PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1 AGEJAFOK_01327 748671.LCRIS_01846 1.22e-190 543.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AGEJAFOK_01328 748671.LCRIS_01846 1.68e-179 513.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AGEJAFOK_01329 748671.LCRIS_01845 0.0 1187.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter ndvA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AGEJAFOK_01331 748671.LCRIS_01839 8.32e-157 440.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,3F3Y0@33958|Lactobacillaceae 91061|Bacilli K response regulator vanR - - - - - - - - - - - Response_reg,Trans_reg_C AGEJAFOK_01332 748671.LCRIS_01838 9.28e-271 741.0 COG5002@1|root,COG5002@2|Bacteria,1TRZ0@1239|Firmicutes,4H9U1@91061|Bacilli,3FC2N@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA AGEJAFOK_01333 748671.LCRIS_01837 0.0 1043.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,3F3UE@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M AGEJAFOK_01334 748671.LCRIS_01836 7.79e-186 515.0 COG1794@1|root,COG1794@2|Bacteria,1TQ6M@1239|Firmicutes,4HR12@91061|Bacilli,3FCEP@33958|Lactobacillaceae 91061|Bacilli M Belongs to the aspartate glutamate racemases family racD - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race AGEJAFOK_01335 748671.LCRIS_01835 6.94e-70 211.0 29P5G@1|root,30A3N@2|Bacteria,1U65A@1239|Firmicutes,4IFV3@91061|Bacilli,3F737@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun AGEJAFOK_01336 748671.LCRIS_01834 1.95e-45 146.0 2AS5U@1|root,31HIR@2|Bacteria,1U6VJ@1239|Firmicutes,4IGPG@91061|Bacilli,3F8JX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01337 748671.LCRIS_01833 1.07e-35 121.0 29QQF@1|root,30BQ8@2|Bacteria,1U8GB@1239|Firmicutes,4IIE4@91061|Bacilli,3FAYA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01338 748671.LCRIS_01832 4.48e-34 117.0 2B46M@1|root,31WXN@2|Bacteria,1U6SR@1239|Firmicutes,4IGKA@91061|Bacilli,3F8F7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01339 748671.LCRIS_01831 0.0 932.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,3F4AD@33958|Lactobacillaceae 91061|Bacilli C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 AGEJAFOK_01340 525365.HMPREF0548_1543 0.0 1470.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HB1D@91061|Bacilli,3F4CE@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 31 family agl - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31 AGEJAFOK_01341 525365.HMPREF0548_1544 0.0 884.0 COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,4HF7F@91061|Bacilli,3F57U@33958|Lactobacillaceae 91061|Bacilli S Archaea bacterial proteins of unknown function - - - ko:K06921 - - - - ko00000 - - - ATPase_2,DUF234 AGEJAFOK_01342 1423767.BALU01000001_gene1436 1.89e-23 89.0 2BRGN@1|root,32KFM@2|Bacteria,1U87Q@1239|Firmicutes,4II5E@91061|Bacilli,3FAND@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01344 405566.lhv_1640 3.11e-13 70.9 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AGEJAFOK_01345 748671.LCRIS_00065 1.38e-107 309.0 COG1670@1|root,COG1670@2|Bacteria,1V7MA@1239|Firmicutes,4I36F@91061|Bacilli,3F9GD@33958|Lactobacillaceae 91061|Bacilli J FR47-like protein - - - - - - - - - - - - Acetyltransf_3 AGEJAFOK_01346 748671.LCRIS_00066 3.37e-50 158.0 COG4892@1|root,COG4892@2|Bacteria,1V64Y@1239|Firmicutes,4HNUM@91061|Bacilli,3F812@33958|Lactobacillaceae 91061|Bacilli S Cytochrome B5 - - - - - - - - - - - - Cyt-b5 AGEJAFOK_01347 748671.LCRIS_00067 3.92e-215 593.0 COG0204@1|root,COG0204@2|Bacteria,1V2F4@1239|Firmicutes,4IF2T@91061|Bacilli,3F5FU@33958|Lactobacillaceae 91061|Bacilli I Phosphate acyltransferases arbZ - - - - - - - - - - - Acyltransferase AGEJAFOK_01348 748671.LCRIS_00068 5.48e-235 645.0 COG1442@1|root,COG1442@2|Bacteria,1VGDI@1239|Firmicutes,4IPQC@91061|Bacilli,3FBE4@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 AGEJAFOK_01349 748671.LCRIS_00069 1.91e-236 649.0 COG1442@1|root,COG1442@2|Bacteria,1VGDI@1239|Firmicutes,4I0ZW@91061|Bacilli,3FCDT@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 AGEJAFOK_01350 748671.LCRIS_00070 7.23e-201 556.0 COG1442@1|root,COG1442@2|Bacteria,1UY4M@1239|Firmicutes,4IEY6@91061|Bacilli,3F4YZ@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 arbx - - - - - - - - - - - Glyco_transf_8 AGEJAFOK_01351 748671.LCRIS_00071 4.19e-192 531.0 COG0204@1|root,COG0204@2|Bacteria,1V9P5@1239|Firmicutes,4IPQB@91061|Bacilli,3F4RC@33958|Lactobacillaceae 91061|Bacilli I Acyl-transferase - - - - - - - - - - - - Acyltransferase AGEJAFOK_01353 748671.LCRIS_00072 1.09e-46 149.0 2930D@1|root,3270J@2|Bacteria,1USWD@1239|Firmicutes,4IG6X@91061|Bacilli,3F7S4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01355 748671.LCRIS_00073 3.98e-169 472.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,3F4FB@33958|Lactobacillaceae 91061|Bacilli K response regulator yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C AGEJAFOK_01356 748671.LCRIS_00074 0.0 1139.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,3F45G@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 AGEJAFOK_01357 748671.LCRIS_00075 0.0 894.0 COG4863@1|root,COG4863@2|Bacteria,1V32Y@1239|Firmicutes,4HG2Q@91061|Bacilli,3F4HR@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycH - - - - - - - - - - - YycH AGEJAFOK_01358 748671.LCRIS_00076 7.44e-192 533.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,3F3PV@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycI - - - - - - - - - - - YycI AGEJAFOK_01359 748671.LCRIS_00077 1.19e-188 524.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,3F3S4@33958|Lactobacillaceae 91061|Bacilli S domain protein vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 AGEJAFOK_01360 748671.LCRIS_00078 3.17e-224 627.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,3F45X@33958|Lactobacillaceae 91061|Bacilli O serine protease htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 AGEJAFOK_01361 748671.LCRIS_00079 8.64e-107 308.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,3F3YX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase AGEJAFOK_01362 1423748.BALB01000005_gene728 0.0 936.0 COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,4HG6W@91061|Bacilli,3F4XR@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 AGEJAFOK_01363 748671.LCRIS_00619 2.22e-296 810.0 COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,4HBGT@91061|Bacilli,3F3YJ@33958|Lactobacillaceae 91061|Bacilli E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 AGEJAFOK_01364 1423748.BALB01000005_gene728 6.59e-296 811.0 COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,4HG6W@91061|Bacilli,3F4XR@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 AGEJAFOK_01365 1033837.WANG_1563 1e-156 466.0 COG0732@1|root,COG0732@2|Bacteria,1TT1D@1239|Firmicutes,4HTQA@91061|Bacilli,3F6TD@33958|Lactobacillaceae 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S AGEJAFOK_01366 748671.LCRIS_01106 0.0 974.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,3F4HM@33958|Lactobacillaceae 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase AGEJAFOK_01367 748671.LCRIS_01105 3.68e-276 756.0 COG1106@1|root,COG1106@2|Bacteria,1V2S2@1239|Firmicutes,4HGTD@91061|Bacilli,3F4MP@33958|Lactobacillaceae 91061|Bacilli S AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K06926 - - - - ko00000 - - - AAA_21 AGEJAFOK_01368 748671.LCRIS_01104 0.0 2078.0 COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,4HA94@91061|Bacilli,3F4JF@33958|Lactobacillaceae 91061|Bacilli L DEAD/DEAH box helicase hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF4145,EcoEI_R_C,HSDR_N,Helicase_C,ResIII AGEJAFOK_01369 748671.LCRIS_01103 0.0 1289.0 29V6Q@1|root,30GKE@2|Bacteria,1UG8H@1239|Firmicutes,4IF4J@91061|Bacilli,3F5M6@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP AGEJAFOK_01371 748671.LCRIS_01101 2.52e-303 826.0 COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,4HG8Z@91061|Bacilli,3F483@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase XK27_01810 - - - - - - - - - - - Metallophos AGEJAFOK_01372 748671.LCRIS_01100 1.43e-80 239.0 COG3576@1|root,COG3576@2|Bacteria,1VW4G@1239|Firmicutes,4HW37@91061|Bacilli,3F6IW@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx AGEJAFOK_01373 748671.LCRIS_01099 1.65e-303 828.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HEKH@91061|Bacilli,3F4P5@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 AGEJAFOK_01374 891391.LAC30SC_02360 0.0 900.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,3FCFA@33958|Lactobacillaceae 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 AGEJAFOK_01375 525365.HMPREF0548_0217 5.93e-50 171.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F587@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC AGEJAFOK_01376 525365.HMPREF0548_0217 6.55e-76 239.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F587@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC AGEJAFOK_01377 1423754.BALY01000012_gene245 1.45e-34 125.0 COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,4HCPK@91061|Bacilli,3F6JX@33958|Lactobacillaceae 91061|Bacilli K FCD - - - - - - - - - - - - FCD,GntR AGEJAFOK_01378 1033837.WANG_1293 2.82e-97 285.0 COG5017@1|root,COG5017@2|Bacteria,1VCGX@1239|Firmicutes,4HMKJ@91061|Bacilli,3F5WF@33958|Lactobacillaceae 91061|Bacilli S Glycosyltransferase family 28 C-terminal domain - - - - - - - - - - - - Glyco_tran_28_C AGEJAFOK_01379 891391.LAC30SC_09360 2.38e-130 384.0 COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,4HC0S@91061|Bacilli,3F6H1@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - ko:K19424 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 AGEJAFOK_01380 411902.CLOBOL_03346 2.56e-66 211.0 COG3955@1|root,COG3955@2|Bacteria,1V8R9@1239|Firmicutes,24IIJ@186801|Clostridia,2233I@1506553|Lachnoclostridium 186801|Clostridia M Domain of unknown function (DUF1919) - - - - - - - - - - - - DUF1919 AGEJAFOK_01381 1033837.WANG_1292 5.18e-109 328.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HVYS@91061|Bacilli,3FBY0@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 AGEJAFOK_01382 1033837.WANG_1290 2.94e-94 283.0 COG0110@1|root,COG0110@2|Bacteria,1VHW4@1239|Firmicutes,4HNPZ@91061|Bacilli 91061|Bacilli S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep,Hexapep_2 AGEJAFOK_01384 1033837.WANG_1287 3.38e-91 282.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HGSR@91061|Bacilli,3FBSG@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 AGEJAFOK_01385 1033837.WANG_1286 1.94e-188 541.0 COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HC84@91061|Bacilli,3F48Q@33958|Lactobacillaceae 91061|Bacilli S Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C AGEJAFOK_01386 1545701.LACWKB10_0759 2.39e-85 258.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3F4KX@33958|Lactobacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim AGEJAFOK_01387 1545701.LACWKB10_0758 3.05e-53 172.0 COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,4HMTB@91061|Bacilli,3FCBX@33958|Lactobacillaceae 91061|Bacilli GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.200 ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_EIIA_2 AGEJAFOK_01388 1545701.LACWKB10_0757 3.94e-254 704.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HA1Q@91061|Bacilli,3F427@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component - - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT AGEJAFOK_01389 1545701.LACWKB10_0756 1.38e-46 151.0 COG3414@1|root,COG3414@2|Bacteria,1VCNU@1239|Firmicutes,4HM3X@91061|Bacilli,3F7YJ@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB AGEJAFOK_01390 1545701.LACWKB10_0755 8.46e-98 286.0 COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,4I1SJ@91061|Bacilli,3F8MH@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 AGEJAFOK_01391 1545701.LACWKB10_0754 1.55e-82 250.0 COG0794@1|root,COG0794@2|Bacteria,1TQ04@1239|Firmicutes,4HGZ0@91061|Bacilli,3F7HT@33958|Lactobacillaceae 91061|Bacilli M SIS domain - - - - - - - - - - - - SIS AGEJAFOK_01392 1545701.LACWKB10_0753 3.53e-63 199.0 COG0794@1|root,COG0794@2|Bacteria,1UYG2@1239|Firmicutes,4HE2U@91061|Bacilli,3FB4E@33958|Lactobacillaceae 91061|Bacilli M SIS domain hxlB - 5.3.1.27 ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05339,R09780 RC00377 ko00000,ko00001,ko00002,ko01000 - - - SIS AGEJAFOK_01393 1545701.LACWKB10_0752 5.28e-215 619.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HDAQ@91061|Bacilli,3F75H@33958|Lactobacillaceae 91061|Bacilli GKT Mga helix-turn-helix domain - - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 AGEJAFOK_01394 324831.LGAS_1507 7.7e-126 363.0 COG2963@1|root,COG2963@2|Bacteria,1V1QC@1239|Firmicutes,4HH7E@91061|Bacilli,3F5BG@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - HTH_28,HTH_Tnp_1 AGEJAFOK_01395 748671.LCRIS_00290 0.0 1546.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR AGEJAFOK_01396 748671.LCRIS_00291 0.0 2390.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,3F4ET@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 AGEJAFOK_01397 748671.LCRIS_00292 0.0 2411.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,3F3KF@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 AGEJAFOK_01398 748671.LCRIS_00293 7.71e-157 440.0 COG1989@1|root,COG1989@2|Bacteria,1W118@1239|Firmicutes,4HZ6B@91061|Bacilli,3F863@33958|Lactobacillaceae 91061|Bacilli NOU Bacterial Peptidase A24 N-terminal domain comC - 3.4.23.43 ko:K02236 - M00429 - - ko00000,ko00002,ko01000,ko02044 - - - DiS_P_DiS,Peptidase_A24 AGEJAFOK_01399 748671.LCRIS_00294 1.47e-91 268.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,3F64B@33958|Lactobacillaceae 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 AGEJAFOK_01400 748671.LCRIS_00295 1.39e-106 307.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,3F3RX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 AGEJAFOK_01401 748671.LCRIS_00296 0.0 1368.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,3F3JR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 AGEJAFOK_01402 1423790.BN53_01690 1.08e-229 644.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HCB9@91061|Bacilli,3F5HM@33958|Lactobacillaceae 91061|Bacilli L DDE superfamily endonuclease - - - - - - - - - - - - DDE_5 AGEJAFOK_01403 748671.LCRIS_01499 0.0 972.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,3F3NU@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA AGEJAFOK_01404 748671.LCRIS_01500 3.52e-163 457.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,3F421@33958|Lactobacillaceae 91061|Bacilli K response regulator csrR - - - - - - - - - - - Response_reg,Trans_reg_C AGEJAFOK_01405 748671.LCRIS_01501 2.19e-125 357.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,3F61Z@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized ACR, COG1399 ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 AGEJAFOK_01406 748671.LCRIS_01502 4.63e-275 752.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,3F3QC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 AGEJAFOK_01407 748671.LCRIS_01503 5.09e-78 232.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,3F7QN@33958|Lactobacillaceae 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS AGEJAFOK_01408 748671.LCRIS_01504 9.22e-141 397.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,3F47C@33958|Lactobacillaceae 91061|Bacilli H Hydrolase, HD family yqeK - - - - - - - - - - - HD AGEJAFOK_01409 748671.LCRIS_01505 1.02e-156 439.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,3F4D6@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like AGEJAFOK_01410 272621.LBA1531 5.03e-256 703.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,3F4JU@33958|Lactobacillaceae 91061|Bacilli S Ribosome biogenesis GTPase YqeH yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 AGEJAFOK_01411 405566.lhv_1595 6.85e-109 315.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,3F46V@33958|Lactobacillaceae 91061|Bacilli S HAD phosphatase, family IIIA yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase AGEJAFOK_01412 748671.LCRIS_01776 2.47e-254 700.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F431@33958|Lactobacillaceae 91061|Bacilli L Putative transposase DNA-binding domain tnpB - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon AGEJAFOK_01413 891391.LAC30SC_08310 1.25e-192 540.0 COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,4HCES@91061|Bacilli,3F5RC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add - 3.5.4.2,3.5.4.4 ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 M00236 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - A_deaminase AGEJAFOK_01414 1423748.BALB01000003_gene397 8.69e-76 226.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,3F6HZ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 AGEJAFOK_01415 748671.LCRIS_01516 9.64e-38 126.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,3F7CQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p AGEJAFOK_01416 748671.LCRIS_01517 1.07e-93 274.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,3F4MS@33958|Lactobacillaceae 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N AGEJAFOK_01417 1122152.AUEI01000004_gene931 6.18e-123 361.0 COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,4HB17@91061|Bacilli,3F4T0@33958|Lactobacillaceae 91061|Bacilli F Nucleoside rihC - 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro AGEJAFOK_01418 1545701.LACWKB10_0497 1.1e-128 374.0 COG1176@1|root,COG1176@2|Bacteria,1TRUC@1239|Firmicutes,4I4AN@91061|Bacilli,3F4M4@33958|Lactobacillaceae 91061|Bacilli E Binding-protein-dependent transport system inner membrane component - - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 AGEJAFOK_01419 748671.LCRIS_00995 1.58e-140 397.0 COG0586@1|root,COG0586@2|Bacteria,1V2XQ@1239|Firmicutes,4IPZ1@91061|Bacilli,3FBF1@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein yngC - - - - - - - - - - - SNARE_assoc AGEJAFOK_01420 748671.LCRIS_00996 0.0 1178.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,3F3MY@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N AGEJAFOK_01421 748671.LCRIS_00997 1.88e-309 843.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,3F4ZA@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 AGEJAFOK_01422 525365.HMPREF0548_0995 0.0 1032.0 COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,3F3WT@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Acyl_transf_3 AGEJAFOK_01423 748671.LCRIS_01000 6.82e-223 614.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,3F4F1@33958|Lactobacillaceae 91061|Bacilli J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 AGEJAFOK_01424 748671.LCRIS_01001 1.18e-183 511.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HI3D@91061|Bacilli,3F41Y@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short AGEJAFOK_01425 748671.LCRIS_01002 3.57e-47 151.0 COG5416@1|root,COG5416@2|Bacteria,1VIG5@1239|Firmicutes,4HP5V@91061|Bacilli,3F7IW@33958|Lactobacillaceae 91061|Bacilli S Lipopolysaccharide assembly protein A domain - - - - - - - - - - - - LapA_dom AGEJAFOK_01426 748671.LCRIS_01003 5.14e-38 127.0 COG0333@1|root,COG0333@2|Bacteria,1VKMZ@1239|Firmicutes,4HR2Q@91061|Bacilli,3F7ZT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p AGEJAFOK_01427 748671.LCRIS_01004 0.0 1061.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HC2M@91061|Bacilli,3F45U@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family yfkN - 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos AGEJAFOK_01428 1423767.BALU01000008_gene558 1.25e-38 129.0 29PGH@1|root,30AEN@2|Bacteria,1U6JJ@1239|Firmicutes,4IGC1@91061|Bacilli,3F81E@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2929) - - - - - - - - - - - - DUF2929 AGEJAFOK_01429 748671.LCRIS_01006 0.0 2019.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,3F4AM@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon AGEJAFOK_01457 748671.LCRIS_00444 1.72e-286 782.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4IPQK@91061|Bacilli,3FC1E@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase 4-like domain - - 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 AGEJAFOK_01458 748671.LCRIS_00445 1.75e-254 697.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli,3F47X@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 2.4.1.208 ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 - R05164,R10865 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 AGEJAFOK_01459 748671.LCRIS_00446 5.35e-224 620.0 COG0392@1|root,COG0392@2|Bacteria,1TR9T@1239|Firmicutes,4IQVI@91061|Bacilli,3FBJD@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM AGEJAFOK_01460 748671.LCRIS_00447 0.0 1357.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase AGEJAFOK_01461 525365.HMPREF0548_1882 1.3e-40 134.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,3F7IQ@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG AGEJAFOK_01462 748671.LCRIS_00449 0.0 1526.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,3F4EC@33958|Lactobacillaceae 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 AGEJAFOK_01463 748671.LCRIS_00450 1.58e-101 294.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,3F65B@33958|Lactobacillaceae 91061|Bacilli J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB AGEJAFOK_01464 748671.LCRIS_00029 5.61e-38 150.0 COG0810@1|root,COG0810@2|Bacteria,1UHXS@1239|Firmicutes,4ISA8@91061|Bacilli,3F7D9@33958|Lactobacillaceae 91061|Bacilli M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal AGEJAFOK_01465 748671.LCRIS_00025 3.17e-189 525.0 COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,4HK25@91061|Bacilli,3F3MV@33958|Lactobacillaceae 91061|Bacilli S Putative ABC-transporter type IV - - - - - - - - - - - - ABC_trans_CmpB AGEJAFOK_01467 1380386.JIAW01000014_gene2798 4.11e-124 372.0 COG0531@1|root,COG0531@2|Bacteria,2IDWU@201174|Actinobacteria,238HU@1762|Mycobacteriaceae 201174|Actinobacteria E thought to be involved in transport amino acids across the membrane potE - - - - - - - - - - - AA_permease_2 AGEJAFOK_01469 326425.lhe_0043 2.67e-35 120.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,3F85E@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 AGEJAFOK_01470 525365.HMPREF0548_1818 6.66e-27 109.0 COG1266@1|root,COG1266@2|Bacteria,1VPST@1239|Firmicutes,4HYU9@91061|Bacilli,3F7Q6@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi AGEJAFOK_01472 97137.C821_00236 1.25e-94 286.0 29NJE@1|root,30GYN@2|Bacteria,1UGVU@1239|Firmicutes,4IF93@91061|Bacilli,3F60Q@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 AGEJAFOK_01473 1033837.WANG_1457 4.82e-144 411.0 29NJE@1|root,30GE4@2|Bacteria,1UFUT@1239|Firmicutes,4IEZ0@91061|Bacilli,3F51E@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19 AGEJAFOK_01476 326425.lhe_0041 2.41e-39 131.0 29P9K@1|root,30A7Q@2|Bacteria,1U6AW@1239|Firmicutes,4IG2B@91061|Bacilli,3F7H3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01477 891391.LAC30SC_01605 4.63e-32 112.0 28SUC@1|root,2ZF42@2|Bacteria,1W27Y@1239|Firmicutes,4HZNS@91061|Bacilli,3F942@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_17 AGEJAFOK_01478 1423758.BN55_04395 6.72e-177 499.0 COG0444@1|root,COG0444@2|Bacteria,1V4H8@1239|Firmicutes,4HRZY@91061|Bacilli,3F4EP@33958|Lactobacillaceae 91061|Bacilli EP Plasmid replication protein - - - - - - - - - - - - RNA_helicase,Rep_2 AGEJAFOK_01479 7460.GB53495-PA 6.76e-101 301.0 2EDPM@1|root,2SJ9G@2759|Eukaryota,3AEI4@33154|Opisthokonta,3BYB3@33208|Metazoa,3DEAP@33213|Bilateria,423YA@6656|Arthropoda,3SS3P@50557|Insecta 33208|Metazoa S helix_turn_helix, Deoxyribose operon repressor - - - - - - - - - - - - DeoRC,HTH_DeoR AGEJAFOK_01480 575594.ACOH01000005_gene1216 2.58e-220 612.0 COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,4HBNW@91061|Bacilli,3F58F@33958|Lactobacillaceae 91061|Bacilli S Beta-lactamase superfamily domain ulaG - - ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 M00550 R07677 RC02793 ko00000,ko00001,ko00002,ko01000 - - - Lactamase_B_2,Lactamase_B_3 AGEJAFOK_01481 575594.ACOH01000005_gene1217 4.93e-80 240.0 COG1762@1|root,COG1762@2|Bacteria,1V892@1239|Firmicutes,4IQ69@91061|Bacilli,3F6HA@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_EIIA_2 AGEJAFOK_01482 1114972.AUAW01000004_gene402 1.97e-294 811.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HB7T@91061|Bacilli,3FC40@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component sgaT - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT AGEJAFOK_01483 1114972.AUAW01000004_gene403 1.13e-40 136.0 COG3414@1|root,COG3414@2|Bacteria,1VCTE@1239|Firmicutes,4HNIF@91061|Bacilli,3FBMT@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit ulaB - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB AGEJAFOK_01484 575594.ACOH01000005_gene1220 2.85e-115 334.0 COG0269@1|root,COG0269@2|Bacteria,1TSHP@1239|Firmicutes,4HCA8@91061|Bacilli,3F3YT@33958|Lactobacillaceae 91061|Bacilli G Orotidine 5'-phosphate decarboxylase / HUMPS family ulaD - 4.1.1.85,4.1.2.43 ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 M00345,M00550,M00580 R05338,R07125 RC00421,RC00422,RC01721 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase AGEJAFOK_01485 575594.ACOH01000005_gene1221 1.78e-163 462.0 COG3623@1|root,COG3623@2|Bacteria,1TSMS@1239|Firmicutes,4HBBU@91061|Bacilli,3F5GZ@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase-like TIM barrel sga - 5.1.3.22 ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R03244 RC00540 ko00000,ko00001,ko00002,ko01000 - - - AP_endonuc_2 AGEJAFOK_01486 908339.HMPREF9265_1949 1.52e-157 443.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,3F43P@33958|Lactobacillaceae 91061|Bacilli G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source araD GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II AGEJAFOK_01487 575594.ACOH01000004_gene1258 5.85e-86 260.0 COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,4HDVJ@91061|Bacilli,3F60K@33958|Lactobacillaceae 91061|Bacilli L haloacid dehalogenase-like hydrolase nt5e - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 AGEJAFOK_01488 585524.HMPREF0493_1553 0.0 1570.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N AGEJAFOK_01489 748671.LCRIS_00646 1.01e-22 90.1 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,3F4M8@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF772 AGEJAFOK_01490 1423748.BALB01000010_gene1069 7.51e-16 77.0 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,3F4M8@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF772 AGEJAFOK_01491 748671.LCRIS_00333 1.21e-72 221.0 COG0454@1|root,COG0456@2|Bacteria,1VN9V@1239|Firmicutes,4IQB1@91061|Bacilli,3F7PZ@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_7 AGEJAFOK_01493 1033837.WANG_0028 4.4e-86 254.0 COG3279@1|root,COG3279@2|Bacteria,1VD10@1239|Firmicutes,4HMF3@91061|Bacilli,3F6QC@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR AGEJAFOK_01494 1033837.WANG_0029 6.11e-66 203.0 2A0WQ@1|root,30P1T@2|Bacteria,1U66T@1239|Firmicutes,4IFX9@91061|Bacilli,3F77R@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 AGEJAFOK_01495 748671.LCRIS_00334 2.64e-134 380.0 COG0693@1|root,COG0693@2|Bacteria,1V3UV@1239|Firmicutes,4IQYM@91061|Bacilli,3F3T7@33958|Lactobacillaceae 91061|Bacilli S DJ-1/PfpI family - - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI AGEJAFOK_01496 748671.LCRIS_00335 2.7e-153 431.0 COG0546@1|root,COG0546@2|Bacteria,1UMZH@1239|Firmicutes,4IU43@91061|Bacilli,3FBY3@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 AGEJAFOK_01497 748671.LCRIS_00336 7.36e-172 480.0 COG0730@1|root,COG0730@2|Bacteria,1VR9G@1239|Firmicutes,4HV4W@91061|Bacilli,3F3TR@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE AGEJAFOK_01498 748671.LCRIS_00337 1.34e-161 452.0 COG0406@1|root,COG0406@2|Bacteria,1TQF1@1239|Firmicutes,4I2XH@91061|Bacilli,3F4RY@33958|Lactobacillaceae 91061|Bacilli G Belongs to the phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 AGEJAFOK_01499 748671.LCRIS_00338 5.08e-207 573.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3F4KJ@33958|Lactobacillaceae 91061|Bacilli P cation diffusion facilitator family transporter - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer AGEJAFOK_01500 748671.LCRIS_00339 2.42e-33 115.0 29PJE@1|root,30AHJ@2|Bacteria,1U6P8@1239|Firmicutes,4IGG9@91061|Bacilli,3F88U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01501 748671.LCRIS_00340 9.82e-164 457.0 COG0588@1|root,COG0588@2|Bacteria,1V2UT@1239|Firmicutes,4HGRK@91061|Bacilli,3F443@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 AGEJAFOK_01502 748671.LCRIS_00341 2.32e-234 643.0 COG4639@1|root,COG4639@2|Bacteria,1TQKR@1239|Firmicutes,4HF9B@91061|Bacilli,3F51A@33958|Lactobacillaceae 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_33,Metallophos,RNA_lig_T4_1 AGEJAFOK_01503 405566.lhv_0361 2.13e-66 203.0 2DS5S@1|root,33ENY@2|Bacteria,1VKTU@1239|Firmicutes,4HSXX@91061|Bacilli,3F6MW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01504 748671.LCRIS_00344 0.0 915.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F49B@33958|Lactobacillaceae 91061|Bacilli E Peptidase C1-like family pepC - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 AGEJAFOK_01505 748671.LCRIS_00345 4.51e-69 208.0 2BRXH@1|root,32KXS@2|Bacteria,1U6EY@1239|Firmicutes,4IG6S@91061|Bacilli,3F7RT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01506 748671.LCRIS_00346 5.22e-131 371.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,3F65D@33958|Lactobacillaceae 91061|Bacilli F dUTP diphosphatase dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase AGEJAFOK_01507 748671.LCRIS_00347 0.0 886.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,3F3W8@33958|Lactobacillaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI AGEJAFOK_01508 748671.LCRIS_00348 0.0 1001.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,3F3PR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c AGEJAFOK_01509 748671.LCRIS_00349 0.0 963.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,3F4K7@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g AGEJAFOK_01510 748671.LCRIS_00350 2.45e-98 286.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,3F6HS@33958|Lactobacillaceae 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 AGEJAFOK_01511 748671.LCRIS_00351 2.69e-178 496.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,3F3TD@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind AGEJAFOK_01512 748671.LCRIS_00352 1.55e-122 350.0 COG1595@1|root,COG1595@2|Bacteria,1VG7U@1239|Firmicutes,4HNKD@91061|Bacilli,3F8D5@33958|Lactobacillaceae 91061|Bacilli K Belongs to the sigma-70 factor family comX - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 AGEJAFOK_01513 748671.LCRIS_00353 1.19e-45 147.0 29PH8@1|root,30AFD@2|Bacteria,1U6KC@1239|Firmicutes,4IGD6@91061|Bacilli,3F83D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01514 748671.LCRIS_00354 0.0 989.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N AGEJAFOK_01515 748671.LCRIS_00355 0.0 1136.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,3F4RN@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C AGEJAFOK_01516 748671.LCRIS_00357 3.73e-33 114.0 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,3F86Y@33958|Lactobacillaceae 91061|Bacilli U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE AGEJAFOK_01517 748671.LCRIS_00358 5e-130 369.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,3F55W@33958|Lactobacillaceae 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG AGEJAFOK_01518 748671.LCRIS_00359 2.69e-90 265.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,3F64I@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N AGEJAFOK_01519 748671.LCRIS_00360 1.05e-160 450.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,3F3VQ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 AGEJAFOK_01520 748671.LCRIS_00361 5.48e-201 557.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 AGEJAFOK_01521 748671.LCRIS_00362 1.13e-210 585.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,3F3NI@33958|Lactobacillaceae 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 AGEJAFOK_01522 748671.LCRIS_00363 2.48e-196 546.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,3F412@33958|Lactobacillaceae 91061|Bacilli P Phosphate transport system permease protein PstA pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 AGEJAFOK_01523 748671.LCRIS_00364 5.24e-187 520.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran AGEJAFOK_01524 748671.LCRIS_00365 3.83e-178 496.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB1 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran AGEJAFOK_01525 748671.LCRIS_00366 2.89e-151 426.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,3F46W@33958|Lactobacillaceae 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU AGEJAFOK_01526 748671.LCRIS_00916 1.61e-117 335.0 COG3039@1|root,COG3039@2|Bacteria,1UZVA@1239|Firmicutes,4HH09@91061|Bacilli,3F4KP@33958|Lactobacillaceae 91061|Bacilli L An automated process has identified a potential problem with this gene model - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_3 AGEJAFOK_01528 748671.LCRIS_00370 3.72e-111 320.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,3F4S4@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 AGEJAFOK_01529 748671.LCRIS_00371 1.61e-72 218.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,3F6YA@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N AGEJAFOK_01530 748671.LCRIS_00372 9.32e-189 525.0 COG1340@1|root,COG1340@2|Bacteria,1UI94@1239|Firmicutes,4HFS7@91061|Bacilli,3FBT5@33958|Lactobacillaceae 91061|Bacilli J Ion channel - - 2.1.1.172 ko:K00564,ko:K10716 - - R07234 RC00003 ko00000,ko01000,ko02000,ko03009 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 AGEJAFOK_01531 748671.LCRIS_00373 5.31e-149 419.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,3F4NU@33958|Lactobacillaceae 91061|Bacilli J Methyltransferase rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS AGEJAFOK_01532 748671.LCRIS_00374 6.15e-36 121.0 2CCGD@1|root,30AG2@2|Bacteria,1U6M6@1239|Firmicutes,4IGE1@91061|Bacilli,3F851@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01533 748671.LCRIS_00375 1.08e-117 336.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,3F6IS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam AGEJAFOK_01534 748671.LCRIS_00376 0.0 1129.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3F3P2@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 AGEJAFOK_01535 748671.LCRIS_00377 5.57e-107 315.0 COG1442@1|root,COG1442@2|Bacteria,1V3ET@1239|Firmicutes,4ISZV@91061|Bacilli,3F5F8@33958|Lactobacillaceae 91061|Bacilli M family 8 - - - - - - - - - - - - GT-D,Glyco_transf_8 AGEJAFOK_01536 748671.LCRIS_00379 6.31e-68 206.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,3F7F3@33958|Lactobacillaceae 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd AGEJAFOK_01537 748671.LCRIS_00380 9.21e-142 400.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,3F4JQ@33958|Lactobacillaceae 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 AGEJAFOK_01538 748671.LCRIS_00381 1.18e-46 150.0 29PC5@1|root,30AAD@2|Bacteria,1U6E6@1239|Firmicutes,4IG5Y@91061|Bacilli,3F7PR@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2508) - - - - - - - - - - - - DUF2508 AGEJAFOK_01539 748671.LCRIS_00382 1.15e-146 413.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,3F4JR@33958|Lactobacillaceae 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin AGEJAFOK_01540 748671.LCRIS_00383 1.58e-70 212.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,3F6VW@33958|Lactobacillaceae 91061|Bacilli S Cyclic-di-AMP receptor yaaQ - - - - - - - - - - - CdAMP_rec AGEJAFOK_01541 748671.LCRIS_00384 8.4e-199 551.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,3F50D@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C AGEJAFOK_01542 748671.LCRIS_00385 1.4e-80 238.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,3F864@33958|Lactobacillaceae 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB AGEJAFOK_01543 748671.LCRIS_00386 3.05e-200 555.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,3F4AI@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase AGEJAFOK_01544 748671.LCRIS_00387 4.27e-167 468.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli,3F41B@33958|Lactobacillaceae 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE AGEJAFOK_01545 748671.LCRIS_00388 8.72e-111 319.0 2DNHW@1|root,32XKY@2|Bacteria,1VGAX@1239|Firmicutes,4ISA7@91061|Bacilli,3FBRP@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt AGEJAFOK_01546 748671.LCRIS_00389 3.69e-171 478.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,3F3WV@33958|Lactobacillaceae 91061|Bacilli O Universal bacterial protein YeaZ yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 AGEJAFOK_01547 748671.LCRIS_00390 3.93e-125 356.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,3F522@33958|Lactobacillaceae 91061|Bacilli K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 AGEJAFOK_01548 748671.LCRIS_00391 1.31e-245 675.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,3F4AX@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 AGEJAFOK_01549 1423754.BALY01000062_gene1837 5.6e-133 387.0 COG4974@1|root,COG4974@2|Bacteria,1TQST@1239|Firmicutes,4HPQC@91061|Bacilli,3F47D@33958|Lactobacillaceae 91061|Bacilli L Transposase IS66 family - - - ko:K07484 - - - - ko00000 - - - DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66 AGEJAFOK_01550 1423748.BALB01000032_gene1944 2.24e-162 461.0 COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,4H9WS@91061|Bacilli,3FBX3@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66 AGEJAFOK_01551 1423748.BALB01000032_gene1943 5.51e-46 148.0 2DEEV@1|root,2ZMQ9@2|Bacteria,1W58V@1239|Firmicutes,4I00W@91061|Bacilli,3F7PV@33958|Lactobacillaceae 91061|Bacilli S Transposase C of IS166 homeodomain - - - - - - - - - - - - LZ_Tnp_IS66 AGEJAFOK_01552 1423767.BALU01000026_gene2042 4.01e-84 247.0 COG3436@1|root,COG3436@2|Bacteria,1VAJD@1239|Firmicutes,4HKCG@91061|Bacilli,3F7E1@33958|Lactobacillaceae 91061|Bacilli L PFAM IS66 Orf2 family protein XK27_01125 - - ko:K07484 - - - - ko00000 - - - TnpB_IS66 AGEJAFOK_01553 1423767.BALU01000026_gene2043 9.48e-31 108.0 29PG8@1|root,30AED@2|Bacteria,1U6J6@1239|Firmicutes,4IGBQ@91061|Bacilli,3F80S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01554 891391.LAC30SC_01950 3.06e-53 176.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,3F4GS@33958|Lactobacillaceae 91061|Bacilli C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate bbsF_1 - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 AGEJAFOK_01555 891391.LAC30SC_01955 6.43e-230 639.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,3F4GS@33958|Lactobacillaceae 91061|Bacilli C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate frc - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 AGEJAFOK_01556 1033837.WANG_0089 0.0 984.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family spxB - 1.2.3.3,1.2.5.1,2.2.1.6,4.1.1.8 ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00207,R00226,R01908,R03050,R03145,R04672,R04673,R08648 RC00027,RC00106,RC00620,RC00860,RC01192,RC02744,RC02745,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N AGEJAFOK_01557 748671.LCRIS_00396 0.0 1210.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn AGEJAFOK_01558 748671.LCRIS_00397 8.74e-146 411.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,3F40G@33958|Lactobacillaceae 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N AGEJAFOK_01559 748671.LCRIS_01885 1.27e-58 192.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,3F3T5@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein mdtG2 - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,Sugar_tr AGEJAFOK_01560 748671.LCRIS_01885 1.36e-211 590.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,3F3T5@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein mdtG2 - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,Sugar_tr AGEJAFOK_01561 748671.LCRIS_01884 7.62e-223 615.0 29NN9@1|root,309K7@2|Bacteria,1U59F@1239|Firmicutes,4IF0Q@91061|Bacilli,3F59C@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01562 748671.LCRIS_01883 2.2e-79 236.0 COG1388@1|root,COG1388@2|Bacteria,1U5V5@1239|Firmicutes,4IFIT@91061|Bacilli,3F6J1@33958|Lactobacillaceae 91061|Bacilli M LysM domain lysM - - - - - - - - - - - - AGEJAFOK_01563 748671.LCRIS_01882 0.0 1665.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli,3F3UH@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 AGEJAFOK_01564 1033837.WANG_1386 0.0 907.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,3F4WU@33958|Lactobacillaceae 91061|Bacilli U amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 AGEJAFOK_01565 1033837.WANG_0539 6.93e-34 119.0 COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HMY5@91061|Bacilli,3F7IR@33958|Lactobacillaceae 91061|Bacilli S Sugar efflux transporter for intercellular exchange - - - - - - - - - - - - MtN3_slv AGEJAFOK_01566 748671.LCRIS_01879 5.3e-92 270.0 COG3279@1|root,COG3279@2|Bacteria,1VBF7@1239|Firmicutes,4IPQI@91061|Bacilli,3F7K4@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR AGEJAFOK_01567 748671.LCRIS_01878 3.15e-121 352.0 COG4758@1|root,COG4758@2|Bacteria,1V7WJ@1239|Firmicutes,4HR21@91061|Bacilli,3F6JJ@33958|Lactobacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - DUF2154 AGEJAFOK_01568 272621.LBA1847 2.61e-23 90.1 29PKP@1|root,30AIV@2|Bacteria,1U6RB@1239|Firmicutes,4IGIQ@91061|Bacilli,3F8CU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01569 748671.LCRIS_01875 3.58e-251 693.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli,3F3QW@33958|Lactobacillaceae 91061|Bacilli S Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_4,YkuD AGEJAFOK_01570 748671.LCRIS_01874 9.18e-202 557.0 COG1085@1|root,COG1085@2|Bacteria,1TSNU@1239|Firmicutes,4H9TY@91061|Bacilli,3F3JH@33958|Lactobacillaceae 91061|Bacilli C Domain of unknown function (DUF4931) - - - - - - - - - - - - DUF4931 AGEJAFOK_01571 748671.LCRIS_01873 5.5e-155 434.0 2CBCD@1|root,309KB@2|Bacteria,1U59M@1239|Firmicutes,4IF11@91061|Bacilli,3F5A8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01572 748671.LCRIS_00913 2.43e-95 285.0 COG3595@1|root,COG3595@2|Bacteria,1VKFR@1239|Firmicutes,4HRQ4@91061|Bacilli,3F4TV@33958|Lactobacillaceae 91061|Bacilli S Putative adhesin - - - ko:K11621 ko02020,map02020 - - - ko00000,ko00001 - - - DUF4097 AGEJAFOK_01573 748671.LCRIS_00912 2.33e-130 371.0 COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,4IPZA@91061|Bacilli,3F5R0@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 AGEJAFOK_01574 756499.Desde_3368 3.87e-15 84.7 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1TSHZ@1239|Firmicutes,24D7N@186801|Clostridia 186801|Clostridia C FMN_bind - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind AGEJAFOK_01575 748671.LCRIS_00908 1.63e-109 315.0 COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli,3F5WI@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin AGEJAFOK_01576 748671.LCRIS_00907 1.73e-227 629.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,4HCCP@91061|Bacilli,3F4TY@33958|Lactobacillaceae 91061|Bacilli S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 AGEJAFOK_01578 748671.LCRIS_00906 1.21e-243 668.0 COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,4HC4Y@91061|Bacilli,3F4NH@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolase, choloylglycine hydrolase family protein cbh - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH AGEJAFOK_01579 748671.LCRIS_00905 2.75e-130 370.0 COG0671@1|root,COG0671@2|Bacteria,1U506@1239|Firmicutes,4IES2@91061|Bacilli,3F3M2@33958|Lactobacillaceae 91061|Bacilli I PAP2 superfamily - - - - - - - - - - - - PAP2 AGEJAFOK_01580 748671.LCRIS_00904 1.23e-187 522.0 COG1307@1|root,COG1307@2|Bacteria,1V0RC@1239|Firmicutes,4HBSA@91061|Bacilli,3F4PM@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 - - - - - - - - - - - - DegV AGEJAFOK_01581 748671.LCRIS_00903 1.43e-310 846.0 COG0148@1|root,COG0148@2|Bacteria,1V12I@1239|Firmicutes,4HTD2@91061|Bacilli,3FCCA@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N AGEJAFOK_01582 748671.LCRIS_00902 8.85e-94 280.0 29W71@1|root,30HS8@2|Bacteria,1VZSI@1239|Firmicutes,4IFNQ@91061|Bacilli,3F6RP@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4767) - - - - - - - - - - - - DUF4767 AGEJAFOK_01583 748671.LCRIS_00901 2.08e-95 280.0 COG0778@1|root,COG0778@2|Bacteria,1UYXM@1239|Firmicutes,4HD96@91061|Bacilli,3F667@33958|Lactobacillaceae 91061|Bacilli C nitroreductase yfhC - - - - - - - - - - - Nitroreductase AGEJAFOK_01584 748671.LCRIS_00159 5.67e-278 761.0 COG0477@1|root,COG2814@2|Bacteria,1TSFM@1239|Firmicutes,4HABN@91061|Bacilli,3FBST@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily yqjV - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr AGEJAFOK_01585 1154757.Q5C_00855 3.65e-84 263.0 COG3547@1|root,COG3547@2|Bacteria,1TRSB@1239|Firmicutes,4HDPK@91061|Bacilli 91061|Bacilli L PFAM transposase IS116 IS110 IS902 - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 AGEJAFOK_01586 748671.LCRIS_00649 0.0 1358.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F3K9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the ClpA ClpB family clpE - - ko:K03697 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR AGEJAFOK_01587 748671.LCRIS_00648 5.93e-60 184.0 2EBZ8@1|root,335YI@2|Bacteria,1VFRS@1239|Firmicutes,4HNUK@91061|Bacilli,3F70G@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1827) XK27_09445 - - - - - - - - - - - DUF1827 AGEJAFOK_01588 748671.LCRIS_00640 0.0 1049.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,3F489@33958|Lactobacillaceae 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C AGEJAFOK_01589 1033837.WANG_1012 1.76e-181 508.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3KG@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain hlyX - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 AGEJAFOK_01590 748671.LCRIS_00638 7.76e-98 285.0 2C070@1|root,300GJ@2|Bacteria,1U5U1@1239|Firmicutes,4IFHZ@91061|Bacilli,3F6I5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01591 748671.LCRIS_00637 1.74e-111 320.0 29NVN@1|root,309TR@2|Bacteria,1U5P0@1239|Firmicutes,4IFDJ@91061|Bacilli,3F693@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01592 748671.LCRIS_00636 2.79e-185 516.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,3F4BY@33958|Lactobacillaceae 91061|Bacilli S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX AGEJAFOK_01593 748671.LCRIS_00635 0.0 906.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F4GQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr AGEJAFOK_01594 748671.LCRIS_00634 1.94e-150 426.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 AGEJAFOK_01595 748671.LCRIS_00634 1.04e-48 163.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 AGEJAFOK_01596 748671.LCRIS_00633 7.74e-61 187.0 29PCT@1|root,30AB1@2|Bacteria,1U6EZ@1239|Firmicutes,4IG6T@91061|Bacilli,3F7RU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01597 1423754.BALY01000006_gene1343 2.15e-127 367.0 COG2963@1|root,COG2963@2|Bacteria,1V1QC@1239|Firmicutes,4HH7E@91061|Bacilli,3F65F@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - HTH_28,HTH_Tnp_1 AGEJAFOK_01598 748671.LCRIS_01776 9.83e-261 716.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F431@33958|Lactobacillaceae 91061|Bacilli L Putative transposase DNA-binding domain tnpB - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon AGEJAFOK_01599 748671.LCRIS_00520 1.91e-195 542.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,3F43Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase AGEJAFOK_01600 748671.LCRIS_00519 0.0 981.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase AGEJAFOK_01601 748671.LCRIS_00518 1.03e-261 717.0 COG0438@1|root,COG0438@2|Bacteria,1UHSF@1239|Firmicutes,4HB04@91061|Bacilli,3F428@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 AGEJAFOK_01602 748671.LCRIS_00517 3.02e-171 478.0 COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,4HH6B@91061|Bacilli,3F4WB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid tagA - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB AGEJAFOK_01603 748671.LCRIS_00516 3.68e-93 271.0 COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,4HGWZ@91061|Bacilli,3F65R@33958|Lactobacillaceae 91061|Bacilli IM Glycerol-3-phosphate cytidylyltransferase tagD - 2.7.7.39 ko:K00980 ko00564,map00564 - R00856 RC00002 ko00000,ko00001,ko01000 - - - CTP_transf_like AGEJAFOK_01604 748671.LCRIS_00515 1.87e-159 447.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4IPQD@91061|Bacilli,3FC8N@33958|Lactobacillaceae 91061|Bacilli K UTRA gntR1 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA AGEJAFOK_01605 748671.LCRIS_00514 2.17e-232 642.0 29NKT@1|root,309IS@2|Bacteria,1U569@1239|Firmicutes,4IEXJ@91061|Bacilli,3F4WR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01606 748671.LCRIS_00513 1.15e-54 184.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA2 - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AGEJAFOK_01607 748671.LCRIS_00513 1.01e-302 830.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA2 - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AGEJAFOK_01609 748671.LCRIS_01900 6.36e-230 632.0 COG1609@1|root,COG1609@2|Bacteria,1U6Z4@1239|Firmicutes,4HC2A@91061|Bacilli,3F3ZC@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor yvdE - - - - - - - - - - - LacI,Peripla_BP_3 AGEJAFOK_01610 748671.LCRIS_01901 4.24e-46 154.0 COG2365@1|root,COG2365@2|Bacteria,1W78R@1239|Firmicutes,4IEVA@91061|Bacilli,3F4QQ@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 AGEJAFOK_01611 748671.LCRIS_01641 1.29e-27 109.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,3F4MJ@33958|Lactobacillaceae 91061|Bacilli C ubiquinol oxidase cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I AGEJAFOK_01612 748671.LCRIS_01642 3.75e-168 473.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,3F42G@33958|Lactobacillaceae 91061|Bacilli K rpiR family - - - - - - - - - - - - HTH_6,SIS AGEJAFOK_01613 748671.LCRIS_01643 7.66e-248 682.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4HAHJ@91061|Bacilli,3FB4D@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) - - - ko:K09963 - - - - ko00000 - - - DUF871 AGEJAFOK_01614 1545702.LACWKB8_1494 1.81e-270 749.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system - - 2.7.1.211 ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIB,PTS_EIIC AGEJAFOK_01615 1545702.LACWKB8_1495 1.32e-151 433.0 COG0627@1|root,COG0627@2|Bacteria,1V856@1239|Firmicutes,4HVCY@91061|Bacilli,3F5Y5@33958|Lactobacillaceae 91061|Bacilli S Putative esterase - - - - - - - - - - - - Esterase AGEJAFOK_01616 1033837.WANG_1180 3.39e-154 439.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,3F4T1@33958|Lactobacillaceae 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 AGEJAFOK_01617 1423790.BN53_01365 1.92e-102 307.0 COG1737@1|root,COG1737@2|Bacteria,1TRHY@1239|Firmicutes,4HHA3@91061|Bacilli,3FBJM@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS AGEJAFOK_01619 748671.LCRIS_01646 0.0 903.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator mdr - - - - - - - - - - - MFS_1 AGEJAFOK_01620 748671.LCRIS_01647 7.29e-287 783.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,3F3T0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N AGEJAFOK_01623 748671.LCRIS_01648 5.31e-211 583.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,3F4B9@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA AGEJAFOK_01626 257314.LJ_1134 5.95e-72 224.0 COG3212@1|root,COG3212@2|Bacteria,1VEU1@1239|Firmicutes,4HPJK@91061|Bacilli,3F6RU@33958|Lactobacillaceae 91061|Bacilli S Peptidase propeptide and YPEB domain ykoJ - - - - - - - - - - - PepSY AGEJAFOK_01627 908339.HMPREF9265_1577 8.41e-42 146.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F42F@33958|Lactobacillaceae 91061|Bacilli E alcohol dehydrogenase adh2 - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N AGEJAFOK_01628 748671.LCRIS_00021 5.32e-285 780.0 COG2267@1|root,COG2267@2|Bacteria,1UHVZ@1239|Firmicutes,4ISGG@91061|Bacilli,3F3SU@33958|Lactobacillaceae 91061|Bacilli I Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 AGEJAFOK_01629 891391.LAC30SC_07290 2.46e-302 832.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 AGEJAFOK_01630 525365.HMPREF0548_0850 0.0 1060.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 AGEJAFOK_01631 748671.LCRIS_01310 2.8e-160 449.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,3F564@33958|Lactobacillaceae 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm AGEJAFOK_01632 748671.LCRIS_01309 0.0 1788.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,3F478@33958|Lactobacillaceae 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge AGEJAFOK_01633 748671.LCRIS_01308 4.69e-226 632.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,3F3YC@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N AGEJAFOK_01634 748671.LCRIS_01307 0.0 996.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD2 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 AGEJAFOK_01635 891391.LAC30SC_07260 1.69e-06 48.1 29P84@1|root,30A66@2|Bacteria,1U68Z@1239|Firmicutes,4IG04@91061|Bacilli,3F7C1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01636 272621.LBA1293 2.1e-31 113.0 29P84@1|root,30A66@2|Bacteria,1U68Z@1239|Firmicutes,4IG04@91061|Bacilli,3F7C1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01637 748671.LCRIS_01678 7.8e-10 57.4 2C9NT@1|root,32ZGB@2|Bacteria,1VG8C@1239|Firmicutes,4HN0V@91061|Bacilli,3F749@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3290) - - - - - - - - - - - - DUF3290 AGEJAFOK_01638 748671.LCRIS_01679 3.85e-180 501.0 COG3201@1|root,COG3201@2|Bacteria,1VE5T@1239|Firmicutes,4HMNW@91061|Bacilli,3F3MB@33958|Lactobacillaceae 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter AGEJAFOK_01639 1423754.BALY01000067_gene768 6.09e-233 651.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F6CN@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 AGEJAFOK_01640 748671.LCRIS_01619 1.01e-98 294.0 COG1575@1|root,COG1575@2|Bacteria,1VW8B@1239|Firmicutes,4HW7F@91061|Bacilli,3F50H@33958|Lactobacillaceae 2|Bacteria H UbiA prenyltransferase family menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA AGEJAFOK_01641 525365.HMPREF0548_0404 7.02e-36 122.0 2DP49@1|root,330FY@2|Bacteria,1VH78@1239|Firmicutes,4I168@91061|Bacilli,3F7H5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01642 1423748.BALB01000005_gene683 2.13e-42 148.0 COG1672@1|root,COG1672@2|Bacteria,1V0EH@1239|Firmicutes,4HXBI@91061|Bacilli,3F4KW@33958|Lactobacillaceae 91061|Bacilli S PFAM Archaeal ATPase - - - - - - - - - - - - ATPase_2 AGEJAFOK_01643 1423748.BALB01000005_gene683 9.96e-45 154.0 COG1672@1|root,COG1672@2|Bacteria,1V0EH@1239|Firmicutes,4HXBI@91061|Bacilli,3F4KW@33958|Lactobacillaceae 91061|Bacilli S PFAM Archaeal ATPase - - - - - - - - - - - - ATPase_2 AGEJAFOK_01644 1423748.BALB01000005_gene683 8.08e-108 319.0 COG1672@1|root,COG1672@2|Bacteria,1V0EH@1239|Firmicutes,4HXBI@91061|Bacilli,3F4KW@33958|Lactobacillaceae 91061|Bacilli S PFAM Archaeal ATPase - - - - - - - - - - - - ATPase_2 AGEJAFOK_01645 1423767.BALU01000011_gene231 6.03e-218 601.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,3F4EF@33958|Lactobacillaceae 91061|Bacilli G Fructose-1,6-bisphosphate aldolase, class II fba - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase AGEJAFOK_01646 748671.LCRIS_01623 0.0 1120.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,3F4DE@33958|Lactobacillaceae 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d AGEJAFOK_01647 1423767.BALU01000011_gene229 5.6e-129 370.0 COG1376@1|root,COG1376@2|Bacteria,1V4KP@1239|Firmicutes,4HIBF@91061|Bacilli,3F6PH@33958|Lactobacillaceae 91061|Bacilli M ErfK YbiS YcfS YnhG - - - - - - - - - - - - Rib,YkuD AGEJAFOK_01648 748671.LCRIS_01625 2.23e-197 547.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,3F480@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N AGEJAFOK_01649 748671.LCRIS_01626 9.64e-307 837.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,3F43S@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 AGEJAFOK_01651 748671.LCRIS_01627 1.59e-61 189.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HRGW@91061|Bacilli,3F87Y@33958|Lactobacillaceae 91061|Bacilli KT PspC domain pspC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC AGEJAFOK_01652 1033837.WANG_0286 7.15e-300 822.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,3FCFA@33958|Lactobacillaceae 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 AGEJAFOK_01653 405566.lhv_0511 2.15e-63 200.0 COG3039@1|root,COG3039@2|Bacteria,1UZVA@1239|Firmicutes,4HH09@91061|Bacilli,3F4KP@33958|Lactobacillaceae 91061|Bacilli L An automated process has identified a potential problem with this gene model - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_3 AGEJAFOK_01654 748671.LCRIS_01861 2.63e-50 159.0 2A5EV@1|root,30U4Q@2|Bacteria,1U6B2@1239|Firmicutes,4IG2J@91061|Bacilli,3F7HR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01655 748671.LCRIS_01860 1.25e-143 405.0 COG1309@1|root,COG1309@2|Bacteria,1U9UE@1239|Firmicutes,4HM7U@91061|Bacilli,3F403@33958|Lactobacillaceae 91061|Bacilli K WHG domain - - - - - - - - - - - - TetR_N,WHG AGEJAFOK_01656 748671.LCRIS_01859 3.41e-125 356.0 COG0431@1|root,COG0431@2|Bacteria,1VI8F@1239|Firmicutes,4HPT0@91061|Bacilli,3FCC2@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase azo1 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0052873,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.5.1.36,1.7.1.6 ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 - R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 - - - FMN_red AGEJAFOK_01657 748671.LCRIS_01858 2.58e-126 359.0 COG0431@1|root,COG0431@2|Bacteria,1TT2S@1239|Firmicutes,4HBQI@91061|Bacilli,3F544@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase azr - 1.5.1.36 ko:K22394 ko00740,ko01100,map00740,map01100 - R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 - - - FMN_red AGEJAFOK_01658 748671.LCRIS_01857 9.48e-194 536.0 COG2365@1|root,COG2365@2|Bacteria,1VA24@1239|Firmicutes,4IQXZ@91061|Bacilli,3F4H4@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 AGEJAFOK_01659 748671.LCRIS_01856 5.24e-230 632.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,3F3QR@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE AGEJAFOK_01660 748671.LCRIS_01854 2.99e-75 230.0 COG1286@1|root,COG1286@2|Bacteria,1U58E@1239|Firmicutes,4IEZI@91061|Bacilli,3F552@33958|Lactobacillaceae 91061|Bacilli S Colicin V production protein cvpA - - - - - - - - - - - Colicin_V AGEJAFOK_01661 748671.LCRIS_01853 3.66e-166 465.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,3F3ZX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB AGEJAFOK_01662 748671.LCRIS_01852 1.18e-190 530.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,3F4RU@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc AGEJAFOK_01663 748671.LCRIS_01851 4.99e-178 496.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3F4AE@33958|Lactobacillaceae 91061|Bacilli D Sporulation initiation inhibitor soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 AGEJAFOK_01664 748671.LCRIS_01850 2.48e-196 546.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,3F47R@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc AGEJAFOK_01665 748671.LCRIS_01849 1.1e-59 183.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,3F823@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF951) yyzM - - - - - - - - - - - DUF951 AGEJAFOK_01666 1423748.BALB01000012_gene1231 6.88e-257 705.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,3F3TK@33958|Lactobacillaceae 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C AGEJAFOK_01667 748671.LCRIS_01847 3.93e-176 492.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HH7B@91061|Bacilli,3F4JS@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1129) - - - - - - - - - - - - DUF1129 AGEJAFOK_01668 575605.ACQN01000050_gene1486 6.79e-293 798.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut AGEJAFOK_01669 748671.LCRIS_01241 5.04e-154 432.0 COG1359@1|root,COG1359@2|Bacteria,1VVR5@1239|Firmicutes,4HWFJ@91061|Bacilli,3F5NS@33958|Lactobacillaceae 91061|Bacilli G Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM AGEJAFOK_01670 748671.LCRIS_01242 1.13e-126 360.0 2AJU9@1|root,31AGT@2|Bacteria,1U5E5@1239|Firmicutes,4IF5F@91061|Bacilli,3F5PH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01671 748671.LCRIS_01243 6.93e-140 395.0 COG0583@1|root,COG0583@2|Bacteria,1TT5B@1239|Firmicutes,4HK1M@91061|Bacilli,3F6BZ@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - LysR_substrate AGEJAFOK_01672 748671.LCRIS_01244 4.04e-29 103.0 2CETM@1|root,30AF4@2|Bacteria,1U6K3@1239|Firmicutes,4IGCS@91061|Bacilli,3F82Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01673 748671.LCRIS_01245 1.07e-287 785.0 COG4552@1|root,COG4552@2|Bacteria,1V7PR@1239|Firmicutes,4HV9V@91061|Bacilli,3FBA9@33958|Lactobacillaceae 91061|Bacilli S Sterol carrier protein domain - - - - - - - - - - - - Acetyltransf_9,SCP2_2 AGEJAFOK_01674 748671.LCRIS_01246 1.76e-122 349.0 COG3697@1|root,COG3697@2|Bacteria,1VB3E@1239|Firmicutes,4HMZ5@91061|Bacilli,3F74S@33958|Lactobacillaceae 91061|Bacilli HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase citX - 2.7.7.61 ko:K05964 ko02020,map02020 - R10706 - ko00000,ko00001,ko01000 - - - CitX AGEJAFOK_01675 748671.LCRIS_01247 2.01e-135 388.0 COG0078@1|root,COG0549@1|root,COG0078@2|Bacteria,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,4H9QD@91061|Bacilli,3F3T4@33958|Lactobacillaceae 91061|Bacilli E Belongs to the carbamate kinase family arcC - 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - - AA_kinase AGEJAFOK_01676 891391.LAC30SC_06900 5.39e-84 256.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,3F48K@33958|Lactobacillaceae 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N AGEJAFOK_01677 748671.LCRIS_01250 2.4e-297 811.0 COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,4HCMG@91061|Bacilli,3F4VJ@33958|Lactobacillaceae 91061|Bacilli E Arginine arcA - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf AGEJAFOK_01678 525365.HMPREF0548_0098 3.03e-177 496.0 COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,4HBNZ@91061|Bacilli,3F4XG@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain lysR5 - - - - - - - - - - - HTH_1,LysR_substrate AGEJAFOK_01679 748671.LCRIS_01253 0.0 1440.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HVA4@91061|Bacilli,3F55J@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus - - - - - - - - - - - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase AGEJAFOK_01680 748671.LCRIS_01254 4.97e-64 196.0 2CKSM@1|root,30AC6@2|Bacteria,1U6G8@1239|Firmicutes,4IG8C@91061|Bacilli,3F7UR@33958|Lactobacillaceae 91061|Bacilli S Metal binding domain of Ada - - - - - - - - - - - - Ada_Zn_binding AGEJAFOK_01681 748671.LCRIS_02013 1.03e-65 212.0 COG0477@1|root,COG0477@2|Bacteria,1UHPS@1239|Firmicutes,4HD28@91061|Bacilli,3FBSX@33958|Lactobacillaceae 91061|Bacilli EGP Sugar (and other) transporter - - - ko:K08368 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr AGEJAFOK_01682 748671.LCRIS_02012 7.41e-136 384.0 2AYWY@1|root,31R2N@2|Bacteria,1UPXG@1239|Firmicutes,4IVCM@91061|Bacilli,3F66A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01683 748671.LCRIS_02011 6.63e-147 414.0 COG0664@1|root,COG0664@2|Bacteria,1TVBM@1239|Firmicutes,4HEJG@91061|Bacilli,3F4PI@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, cAMP Regulatory protein crp2 - - ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding AGEJAFOK_01684 748671.LCRIS_02010 0.0 1179.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copA - 3.6.3.3,3.6.3.5,3.6.3.54 ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 - - Cupredoxin_1,E1-E2_ATPase,Hydrolase AGEJAFOK_01685 748671.LCRIS_02009 4.44e-65 197.0 COG4633@1|root,COG4633@2|Bacteria,1U632@1239|Firmicutes,4IFSB@91061|Bacilli,3F6XB@33958|Lactobacillaceae 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 AGEJAFOK_01686 1423767.BALU01000001_gene1598 2.52e-76 228.0 COG4633@1|root,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,4IRVT@91061|Bacilli,3FBQA@33958|Lactobacillaceae 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 AGEJAFOK_01687 1033837.WANG_1626 2.23e-48 169.0 29NJE@1|root,30RS9@2|Bacteria,1U60N@1239|Firmicutes,4IFPF@91061|Bacilli,3F6SP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_19 AGEJAFOK_01691 748671.LCRIS_00641 2.27e-179 501.0 29NJE@1|root,3021E@2|Bacteria,1U628@1239|Firmicutes,4IFR8@91061|Bacilli,3F6V0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_3 AGEJAFOK_01692 748671.LCRIS_00642 0.0 966.0 COG1132@1|root,COG1132@2|Bacteria,1V08F@1239|Firmicutes,4HUKE@91061|Bacilli,3FBEY@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran AGEJAFOK_01693 525365.HMPREF0548_1382 7.23e-50 170.0 COG3595@1|root,COG3595@2|Bacteria,1VKFR@1239|Firmicutes,4HRQ4@91061|Bacilli,3F74T@33958|Lactobacillaceae 91061|Bacilli S Putative adhesin - - - ko:K11621 ko02020,map02020 - - - ko00000,ko00001 - - - DUF4097 AGEJAFOK_01694 1423806.JCM15457_1778 5.6e-11 62.8 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase AGEJAFOK_01695 97137.C821_01517 5.22e-18 76.6 2CF2D@1|root,2ZQXD@2|Bacteria,1W6FI@1239|Firmicutes,4HRT7@91061|Bacilli,3F8NK@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3173) - - - - - - - - - - - - DUF3173 AGEJAFOK_01696 713605.ADHG01000001_gene212 5.45e-72 221.0 2DNGW@1|root,32XFG@2|Bacteria,1TZ4U@1239|Firmicutes,4IGM1@91061|Bacilli,3F8G9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01698 97137.C821_01520 5.2e-119 349.0 COG1674@1|root,COG1674@2|Bacteria,1UHBZ@1239|Firmicutes,4IFC2@91061|Bacilli,3F66I@33958|Lactobacillaceae 91061|Bacilli D ftsk spoiiie - - - - - - - - - - - - - AGEJAFOK_01700 713605.ADHG01000001_gene216 2.13e-53 170.0 29PWD@1|root,30AUR@2|Bacteria,1U74N@1239|Firmicutes,4IGZA@91061|Bacilli,3F8YZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01701 1138822.PL11_10335 4.61e-304 866.0 COG3421@1|root,COG3421@2|Bacteria,1TRVK@1239|Firmicutes,4HAVG@91061|Bacilli,3F61Y@33958|Lactobacillaceae 91061|Bacilli L Type III restriction enzyme, res subunit sthIR - 3.1.21.5 ko:K01156 - - - - ko00000,ko01000,ko02048 - - - ResIII AGEJAFOK_01702 1291743.LOSG293_220290 7.01e-207 603.0 COG2189@1|root,COG2189@2|Bacteria,1TR8A@1239|Firmicutes,4HBP1@91061|Bacilli,3F504@33958|Lactobacillaceae 91061|Bacilli L DNA methylase - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase,TypeIII_RM_meth AGEJAFOK_01703 748671.LCRIS_00241 0.0 1042.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,3F3NV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase AGEJAFOK_01704 1033837.WANG_1862 1.1e-54 183.0 COG1476@1|root,COG1476@2|Bacteria,1UHWD@1239|Firmicutes,4IU4I@91061|Bacilli,3FBYR@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix - - - - - - - - - - - - HTH_3 AGEJAFOK_01705 748671.LCRIS_00238 7.92e-135 382.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,3F49S@33958|Lactobacillaceae 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran AGEJAFOK_01706 748671.LCRIS_00237 1.08e-289 793.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,3F3Y7@33958|Lactobacillaceae 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16169 - - - - ko00000,ko02000 2.A.40,2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease AGEJAFOK_01707 748671.LCRIS_00236 2.73e-201 556.0 COG2207@1|root,COG2207@2|Bacteria,1V8G6@1239|Firmicutes,4HIF6@91061|Bacilli,3FBER@33958|Lactobacillaceae 91061|Bacilli K AraC-like ligand binding domain msmR - - - - - - - - - - - AraC_binding,HTH_18 AGEJAFOK_01708 748671.LCRIS_00235 0.0 982.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepDA - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 AGEJAFOK_01709 748671.LCRIS_00234 7.28e-97 284.0 COG0454@1|root,COG0456@2|Bacteria,1V5SA@1239|Firmicutes,4ISZX@91061|Bacilli,3FBU8@33958|Lactobacillaceae 91061|Bacilli K acetyltransferase - - - - - - - - - - - - Acetyltransf_1 AGEJAFOK_01710 748671.LCRIS_00233 1.89e-312 851.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,3F3P8@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase AGEJAFOK_01711 748671.LCRIS_00232 0.0 1066.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,3F42X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase AGEJAFOK_01712 1033837.WANG_1853 2.38e-88 263.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,3F55D@33958|Lactobacillaceae 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH AGEJAFOK_01713 748671.LCRIS_00230 1.75e-89 263.0 29P4Y@1|root,30A35@2|Bacteria,1U64K@1239|Firmicutes,4IFU4@91061|Bacilli,3F712@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1934) - - - - - - - - - - - - DUF1934 AGEJAFOK_01714 748671.LCRIS_00229 0.0 926.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4IQRC@91061|Bacilli,3FC99@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06885 - - - - ko00000 - - - HD AGEJAFOK_01715 748671.LCRIS_00228 2.53e-56 175.0 29PEC@1|root,30ACI@2|Bacteria,1U6GK@1239|Firmicutes,4IG8S@91061|Bacilli,3F7VQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01716 748671.LCRIS_00227 1.37e-219 605.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli,3F3ZI@33958|Lactobacillaceae 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK AGEJAFOK_01717 748671.LCRIS_00226 5.4e-226 623.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3U2@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N AGEJAFOK_01718 748671.LCRIS_00225 0.0 1016.0 2DKI3@1|root,309IT@2|Bacteria,1U56A@1239|Firmicutes,4IEXK@91061|Bacilli,3F4WY@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - FIVAR,SLAP AGEJAFOK_01719 748671.LCRIS_00224 5.52e-113 331.0 2DKIG@1|root,309K1@2|Bacteria,1U593@1239|Firmicutes,4IF0E@91061|Bacilli,3F586@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - SLAP AGEJAFOK_01720 748671.LCRIS_00223 5.17e-307 840.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,3F4I3@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase AGEJAFOK_01721 748671.LCRIS_00222 9.72e-189 525.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,3F3NH@33958|Lactobacillaceae 91061|Bacilli F pur operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N AGEJAFOK_01722 748671.LCRIS_00221 1.42e-52 165.0 COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,3F7D3@33958|Lactobacillaceae 91061|Bacilli S Biofilm formation stimulator VEG veg - - - - - - - - - - - VEG AGEJAFOK_01723 748671.LCRIS_00219 2.14e-201 558.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,3F3VC@33958|Lactobacillaceae 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD AGEJAFOK_01724 748671.LCRIS_00218 5.17e-129 367.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,3F64F@33958|Lactobacillaceae 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 AGEJAFOK_01725 748671.LCRIS_00217 1.11e-188 523.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,3F3N2@33958|Lactobacillaceae 91061|Bacilli L hydrolase, TatD family tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase AGEJAFOK_01726 748671.LCRIS_00216 0.0 1312.0 COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,3F3XR@33958|Lactobacillaceae 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind AGEJAFOK_01727 748671.LCRIS_00215 0.0 1560.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli,3F4E0@33958|Lactobacillaceae 91061|Bacilli P COG0474 Cation transport ATPase mgtA - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase AGEJAFOK_01728 748671.LCRIS_00214 4.57e-135 382.0 COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4HJVB@91061|Bacilli,3F5HD@33958|Lactobacillaceae 91061|Bacilli S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase AGEJAFOK_01729 748671.LCRIS_00213 4.29e-116 332.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HEJU@91061|Bacilli,3FC8D@33958|Lactobacillaceae 91061|Bacilli F MafB19-like deaminase comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 AGEJAFOK_01730 748671.LCRIS_00212 4.07e-245 673.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,3F3V6@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b AGEJAFOK_01731 748671.LCRIS_00211 1.66e-143 404.0 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HHE2@91061|Bacilli,3F5AJ@33958|Lactobacillaceae 91061|Bacilli E Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP AGEJAFOK_01733 748671.LCRIS_00210 1.43e-144 409.0 2BFBV@1|root,3294Z@2|Bacteria,1UG72@1239|Firmicutes,4IF41@91061|Bacilli,3F5KI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Abi AGEJAFOK_01734 748671.LCRIS_00209 5.69e-100 290.0 COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,4HW8H@91061|Bacilli,3F6ZK@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N AGEJAFOK_01735 748671.LCRIS_00208 6.87e-93 271.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HIUZ@91061|Bacilli,3FB63@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 AGEJAFOK_01736 748671.LCRIS_00207 0.0 884.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F3QA@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepE - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 AGEJAFOK_01737 748671.LCRIS_00206 6.54e-222 612.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,3F4GM@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppF - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY AGEJAFOK_01738 748671.LCRIS_00205 6.08e-253 694.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD - - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY AGEJAFOK_01739 748671.LCRIS_00204 1.11e-239 659.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,3F3W3@33958|Lactobacillaceae 91061|Bacilli EP ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N AGEJAFOK_01740 748671.LCRIS_00203 1.34e-191 535.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,3F42T@33958|Lactobacillaceae 91061|Bacilli P ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 AGEJAFOK_01741 748671.LCRIS_00202 4.39e-267 732.0 COG0516@1|root,COG0516@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,3F3XN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH AGEJAFOK_01742 748671.LCRIS_00201 0.0 1073.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AGEJAFOK_01743 748671.LCRIS_00200 0.0 1060.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AGEJAFOK_01744 748671.LCRIS_00199 1.77e-157 441.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,3F3PN@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. ypgQ - - ko:K06950 - - - - ko00000 - - - HD AGEJAFOK_01745 748671.LCRIS_00198 0.0 882.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F3QA@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepC2 - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 AGEJAFOK_01747 748671.LCRIS_00197 9.39e-71 214.0 2BZTJ@1|root,30A3I@2|Bacteria,1U655@1239|Firmicutes,4IFUX@91061|Bacilli,3F72R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01748 748671.LCRIS_00196 4.06e-306 834.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,3F48J@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b AGEJAFOK_01749 748671.LCRIS_00195 0.0 919.0 2A3XC@1|root,30SFQ@2|Bacteria,1UGQV@1239|Firmicutes,4IF8A@91061|Bacilli,3F5YM@33958|Lactobacillaceae 91061|Bacilli S Fibronectin type III domain - - - - - - - - - - - - fn3 AGEJAFOK_01751 748671.LCRIS_01224 2e-149 420.0 2DVJ8@1|root,33W59@2|Bacteria,1UI90@1239|Firmicutes,4HD3X@91061|Bacilli,3F5JD@33958|Lactobacillaceae 91061|Bacilli S Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 AGEJAFOK_01752 748671.LCRIS_01225 1.22e-136 386.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,3F3YI@33958|Lactobacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR AGEJAFOK_01754 748671.LCRIS_01229 2.83e-205 568.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,3F3PH@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 yitT - - - - - - - - - - - DUF2179,YitT_membrane AGEJAFOK_01755 748671.LCRIS_01230 5.47e-151 424.0 29TNS@1|root,30EWM@2|Bacteria,1U551@1239|Firmicutes,4IEWA@91061|Bacilli,3F4Q6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01756 748671.LCRIS_01231 3.06e-202 560.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,3F44T@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06620 GHMP_kinases_C,GHMP_kinases_N AGEJAFOK_01757 748671.LCRIS_01232 2.95e-283 775.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,3F5BM@33958|Lactobacillaceae 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 AGEJAFOK_01758 748671.LCRIS_01233 0.0 968.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli,3F3UF@33958|Lactobacillaceae 91061|Bacilli E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N AGEJAFOK_01759 748671.LCRIS_01234 0.0 889.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 AGEJAFOK_01760 748671.LCRIS_01235 6.83e-133 376.0 COG0406@1|root,COG0406@2|Bacteria,1V8SE@1239|Firmicutes,4HJCU@91061|Bacilli,3F86H@33958|Lactobacillaceae 91061|Bacilli G Histidine phosphatase superfamily (branch 1) yrgI - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 AGEJAFOK_01762 748671.LCRIS_01886 1.86e-114 328.0 COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,4HIHC@91061|Bacilli,3F6GV@33958|Lactobacillaceae 91061|Bacilli S Macro domain protein ymdB - - - - - - - - - - - Macro AGEJAFOK_01763 748671.LCRIS_00972 1.24e-93 274.0 COG2707@1|root,COG2707@2|Bacteria,1V7JN@1239|Firmicutes,4HINS@91061|Bacilli,3F68U@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF441) ytwI - - - - - - - - - - - DUF441 AGEJAFOK_01764 748671.LCRIS_00973 1.2e-30 107.0 29PJU@1|root,30AHZ@2|Bacteria,1U6Q0@1239|Firmicutes,4IGGY@91061|Bacilli,3F8A1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01765 748671.LCRIS_00974 2.58e-189 526.0 COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,4HBTW@91061|Bacilli,3F3Y9@33958|Lactobacillaceae 91061|Bacilli P cobalt transport cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iSB619.SA_RS14165 CbiQ AGEJAFOK_01766 748671.LCRIS_00975 0.0 1117.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,3F4XP@33958|Lactobacillaceae 91061|Bacilli P ABC transporter, ATP-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 AGEJAFOK_01767 748671.LCRIS_00976 5.38e-125 356.0 COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,4HGAE@91061|Bacilli,3F5A7@33958|Lactobacillaceae 91061|Bacilli S UPF0397 protein - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS AGEJAFOK_01768 748671.LCRIS_00977 8.1e-87 255.0 29PNX@1|root,30AM4@2|Bacteria,1U6UG@1239|Firmicutes,4IGNA@91061|Bacilli,3F8I6@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function DUF1828 - - - - - - - - - - - - DUF1828 AGEJAFOK_01769 326425.lhe_0928 7.91e-14 64.7 29PV8@1|root,30ATG@2|Bacteria,1U734@1239|Firmicutes,4IGXN@91061|Bacilli,3F8WW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01770 748671.LCRIS_00978 2.41e-66 202.0 2CHWU@1|root,34CGV@2|Bacteria,1W494@1239|Firmicutes,4HZJS@91061|Bacilli,3F71N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01771 748671.LCRIS_00979 1.05e-226 624.0 COG2390@1|root,COG2390@2|Bacteria,1VSYQ@1239|Firmicutes,4HU6A@91061|Bacilli,3FCBZ@33958|Lactobacillaceae 91061|Bacilli K Putative sugar-binding domain citR - - - - - - - - - - - Sugar-bind AGEJAFOK_01772 748671.LCRIS_00980 9.28e-317 865.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,4HU4D@91061|Bacilli,3F4FR@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE,ThrE_2 AGEJAFOK_01774 1423748.BALB01000010_gene1095 5.26e-15 80.5 2DKS5@1|root,30AKA@2|Bacteria,1U6TD@1239|Firmicutes,4IGM6@91061|Bacilli,3F8GG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - YSIRK_signal AGEJAFOK_01775 1545702.LACWKB8_1360 0.0 1216.0 COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HBC7@91061|Bacilli,3F4XS@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 38 N-terminal domain mngB - 3.2.1.170 ko:K15524 - - - - ko00000,ko01000 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C AGEJAFOK_01776 1545702.LACWKB8_1359 8.13e-169 504.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HEIQ@91061|Bacilli,3FC4W@33958|Lactobacillaceae 91061|Bacilli G Mga helix-turn-helix domain - - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB AGEJAFOK_01777 1545702.LACWKB8_1361 0.0 964.0 COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HBC7@91061|Bacilli,3F4XS@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 38 N-terminal domain - - 3.2.1.170,3.2.1.24 ko:K01191,ko:K15524 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04131 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C AGEJAFOK_01778 1545702.LACWKB8_1362 4.34e-198 556.0 COG1299@1|root,COG1299@2|Bacteria,1U5J4@1239|Firmicutes,4HDDR@91061|Bacilli,3FCBI@33958|Lactobacillaceae 91061|Bacilli U system, fructose-specific IIC component fptC - - ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.2.1 - - PTS_EIIC AGEJAFOK_01779 411463.EUBVEN_00846 5.84e-50 160.0 COG1445@1|root,COG1445@2|Bacteria,1UVGK@1239|Firmicutes,25N98@186801|Clostridia,25Z4E@186806|Eubacteriaceae 186801|Clostridia G Psort location Cytoplasmic, score 9.98 - - - - - - - - - - - - PTS_IIB AGEJAFOK_01780 1545702.LACWKB8_1364 2.4e-54 175.0 COG1762@1|root,COG1762@2|Bacteria,1V54T@1239|Firmicutes,4HKX6@91061|Bacilli,3FCBH@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.202 ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 AGEJAFOK_01781 1158612.I580_00525 6.56e-86 266.0 COG0778@1|root,COG0778@2|Bacteria,1UY72@1239|Firmicutes,4HNM6@91061|Bacilli,4B4A0@81852|Enterococcaceae 91061|Bacilli C Nitroreductase family sagB - - - - - - - - - - - Nitroreductase AGEJAFOK_01783 1034809.SLUG_00400 8.25e-65 209.0 COG0842@1|root,COG0842@2|Bacteria 2|Bacteria V Transport permease protein - - - ko:K01990,ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3,ABC_tran AGEJAFOK_01784 1034809.SLUG_00390 9.75e-80 249.0 COG1131@1|root,COG1131@2|Bacteria,1UJIK@1239|Firmicutes,4HHH0@91061|Bacilli 91061|Bacilli V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AGEJAFOK_01786 326425.lhe_0037 3.5e-280 768.0 COG0582@1|root,COG0582@2|Bacteria,1U59Y@1239|Firmicutes,4IF1G@91061|Bacilli,3F5BK@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase AGEJAFOK_01787 326425.lhe_0036 4.04e-36 122.0 29PP2@1|root,30AMM@2|Bacteria,1U6VC@1239|Firmicutes,4IGP8@91061|Bacilli,3F8JJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01788 1033837.WANG_1444 1.33e-72 219.0 29PQQ@1|root,30ANX@2|Bacteria,1U6XE@1239|Firmicutes,4IGRP@91061|Bacilli,3F8NV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01789 326425.lhe_0034 5.28e-180 502.0 294J7@1|root,2ZRYS@2|Bacteria,1V478@1239|Firmicutes,4IJ1U@91061|Bacilli,3F60V@33958|Lactobacillaceae 91061|Bacilli S Replication initiation factor - - - - - - - - - - - - Rep_trans AGEJAFOK_01790 326425.lhe_0033 1.36e-171 481.0 COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,4I32F@91061|Bacilli,3F688@33958|Lactobacillaceae 91061|Bacilli D Ftsk spoiiie family protein - - - - - - - - - - - - AAA,FtsK_SpoIIIE AGEJAFOK_01791 326425.lhe_0032 7.06e-110 318.0 29QAB@1|root,30B9G@2|Bacteria,1U7S5@1239|Firmicutes,4IHPH@91061|Bacilli,3FA3K@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01792 326425.lhe_0031 7.2e-84 249.0 29PFJ@1|root,30ADQ@2|Bacteria,1U6I6@1239|Firmicutes,4IGAH@91061|Bacilli,3F7YR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01795 748671.LCRIS_00022 4.38e-150 424.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HK8H@91061|Bacilli,3F3QE@33958|Lactobacillaceae 91061|Bacilli S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC AGEJAFOK_01796 748671.LCRIS_00988 5.51e-284 776.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspC - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 AGEJAFOK_01797 748671.LCRIS_00987 0.0 1245.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,3F4PE@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon AGEJAFOK_01798 748671.LCRIS_00986 7.1e-311 847.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,3F3M3@33958|Lactobacillaceae 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His AGEJAFOK_01799 748671.LCRIS_00985 1.8e-99 288.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,3F6GK@33958|Lactobacillaceae 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase AGEJAFOK_01800 748671.LCRIS_00984 0.0 1465.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS AGEJAFOK_01801 748671.LCRIS_00983 3.8e-80 238.0 29PCU@1|root,30AB2@2|Bacteria,1U6F0@1239|Firmicutes,4IG6U@91061|Bacilli,3F7RV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01802 748671.LCRIS_00982 4.8e-224 617.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,3F47Z@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA AGEJAFOK_01803 748671.LCRIS_00981 1.3e-115 331.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHVB@91061|Bacilli,3F5H1@33958|Lactobacillaceae 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit AGEJAFOK_01804 748671.LCRIS_01141 7.55e-53 166.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc AGEJAFOK_01805 748671.LCRIS_01705 7.53e-163 454.0 COG0406@1|root,COG0406@2|Bacteria,1TQWQ@1239|Firmicutes,4HF2N@91061|Bacilli,3F524@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpm2 - - - - - - - - - - - His_Phos_1 AGEJAFOK_01806 748671.LCRIS_01704 1.47e-158 446.0 COG5549@1|root,COG5549@2|Bacteria,1VW9X@1239|Firmicutes,4HWF8@91061|Bacilli,3F60X@33958|Lactobacillaceae 91061|Bacilli O PFAM peptidase M10A and M12B, matrixin and adamalysin XK27_08875 - - - - - - - - - - - Peptidase_M10 AGEJAFOK_01807 748671.LCRIS_01703 0.0 1502.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase helD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 AGEJAFOK_01808 748671.LCRIS_01702 3e-139 395.0 COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli,3F3VF@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 AGEJAFOK_01809 748671.LCRIS_01701 6.89e-136 385.0 COG1126@1|root,COG1126@2|Bacteria,1UYAZ@1239|Firmicutes,4HE6M@91061|Bacilli,3F4GP@33958|Lactobacillaceae 91061|Bacilli E ABC transporter glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran AGEJAFOK_01810 748671.LCRIS_01700 7.09e-184 512.0 COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,4HF14@91061|Bacilli,3F3WC@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein aatB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 AGEJAFOK_01811 748671.LCRIS_01699 1.36e-96 281.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,3F6HQ@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) domain yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 AGEJAFOK_01812 748671.LCRIS_01698 1.88e-125 357.0 COG2755@1|root,COG2755@2|Bacteria,1VB88@1239|Firmicutes,4IPQF@91061|Bacilli,3F5AR@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 AGEJAFOK_01813 748671.LCRIS_01697 1.95e-218 602.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli,3F42Q@33958|Lactobacillaceae 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK AGEJAFOK_01814 748671.LCRIS_01696 1.48e-134 381.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F4EW@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C AGEJAFOK_01815 748671.LCRIS_01695 1.24e-75 229.0 COG3212@1|root,COG3212@2|Bacteria,1U5TJ@1239|Firmicutes,4IFHH@91061|Bacilli,3F6H2@33958|Lactobacillaceae 91061|Bacilli S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY AGEJAFOK_01816 748671.LCRIS_00255 3.12e-65 201.0 29NJI@1|root,309HE@2|Bacteria,1U53J@1239|Firmicutes,4IEUW@91061|Bacilli,3F4CT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01817 748671.LCRIS_01142 4.52e-114 330.0 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HM4F@91061|Bacilli,3F5F5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 AGEJAFOK_01818 748671.LCRIS_01142 5.57e-22 90.9 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HM4F@91061|Bacilli,3F5F5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 AGEJAFOK_01819 748671.LCRIS_01706 1.08e-307 838.0 COG4640@1|root,COG4640@2|Bacteria,1V6D3@1239|Firmicutes,4IPQE@91061|Bacilli,3F4ZG@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic - - - - - - - - - - - - zf-ribbon_3 AGEJAFOK_01820 748671.LCRIS_01707 1.34e-162 455.0 29NN1@1|root,309JZ@2|Bacteria,1U591@1239|Firmicutes,4IF0C@91061|Bacilli,3F57G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4145 AGEJAFOK_01821 748671.LCRIS_01708 0.0 1641.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL3 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 AGEJAFOK_01822 748671.LCRIS_01709 6.28e-87 256.0 COG2893@1|root,COG2893@2|Bacteria,1VI0C@1239|Firmicutes,4I1S0@91061|Bacilli,3F6IK@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man AGEJAFOK_01823 748671.LCRIS_01710 1.42e-57 179.0 29PBU@1|root,30AA1@2|Bacteria,1U6DS@1239|Firmicutes,4IG5H@91061|Bacilli,3F7P4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01824 272621.LBA1686 4.65e-14 65.5 29PT6@1|root,30ARD@2|Bacteria,1U70J@1239|Firmicutes,4IGUW@91061|Bacilli,3F8TF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01825 748671.LCRIS_01711 7.81e-238 654.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4HD98@91061|Bacilli,3FCC6@33958|Lactobacillaceae 91061|Bacilli EJ L-asparaginase, type I ansA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase AGEJAFOK_01826 748671.LCRIS_01712 8.28e-176 491.0 COG1737@1|root,COG1737@2|Bacteria,1TR3Z@1239|Firmicutes,4IQVZ@91061|Bacilli,3FBJI@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - ko:K03481 - - - - ko00000,ko03000 - - - HTH_6,SIS AGEJAFOK_01827 748671.LCRIS_01713 0.0 925.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9TM@91061|Bacilli,3F4W5@33958|Lactobacillaceae 91061|Bacilli G Family 4 glycosyl hydrolase C-terminal domain malH - 3.2.1.122 ko:K01232 ko00500,map00500 - R00837,R00838,R06113 RC00049 ko00000,ko00001,ko01000 - GH4 - Glyco_hydro_4,Glyco_hydro_4C AGEJAFOK_01828 525365.HMPREF0548_0329 7.14e-139 405.0 COG4292@1|root,COG4292@2|Bacteria,1VAA8@1239|Firmicutes,4HMPC@91061|Bacilli,3F523@33958|Lactobacillaceae 91061|Bacilli S Bacterial low temperature requirement A protein (LtrA) ltrA - - - - - - - - - - - LtrA AGEJAFOK_01831 748671.LCRIS_00438 1.76e-234 645.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,3F3NQ@33958|Lactobacillaceae 91061|Bacilli C Ferredoxin--NADP reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 AGEJAFOK_01832 748671.LCRIS_00437 3.99e-149 420.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F4KG@33958|Lactobacillaceae 91061|Bacilli S SNARE-like domain protein dedA - - ko:K03975 - - - - ko00000 - - - SNARE_assoc AGEJAFOK_01833 748671.LCRIS_00436 2.15e-137 389.0 COG4478@1|root,COG4478@2|Bacteria,1V7UW@1239|Firmicutes,4HHH4@91061|Bacilli,3F4YP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1461) - - - - - - - - - - - - DUF1461 AGEJAFOK_01834 748671.LCRIS_00435 6.38e-184 511.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,3F49D@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like AGEJAFOK_01835 748671.LCRIS_00434 4.25e-119 342.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,3F66P@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1027) yutD - - - - - - - - - - - DUF1027 AGEJAFOK_01836 748671.LCRIS_00433 0.0 942.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli,3FC1D@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family sasH - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos,SLH AGEJAFOK_01837 748671.LCRIS_00432 9.89e-74 220.0 2C26E@1|root,3424N@2|Bacteria,1VX4A@1239|Firmicutes,4HXT9@91061|Bacilli,3F70Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01838 748671.LCRIS_00431 0.0 920.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3F4E3@33958|Lactobacillaceae 91061|Bacilli C glycerophosphoryl diester phosphodiesterase - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD AGEJAFOK_01839 748671.LCRIS_00430 1.23e-231 638.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,3F4AA@33958|Lactobacillaceae 91061|Bacilli K catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 AGEJAFOK_01840 748671.LCRIS_00429 1.6e-272 744.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,3F3X5@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 AGEJAFOK_01841 748671.LCRIS_02013 2.71e-222 619.0 COG0477@1|root,COG0477@2|Bacteria,1UHPS@1239|Firmicutes,4HD28@91061|Bacilli,3FBSX@33958|Lactobacillaceae 91061|Bacilli EGP Sugar (and other) transporter - - - ko:K08368 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr AGEJAFOK_01842 1033837.WANG_1480 6.46e-27 98.2 29PGF@1|root,30AEK@2|Bacteria,1U6JH@1239|Firmicutes,4IGBZ@91061|Bacilli,3F819@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01843 748671.LCRIS_02015 1.59e-268 734.0 29NJT@1|root,309HR@2|Bacteria,1U547@1239|Firmicutes,4IEVJ@91061|Bacilli,3F4IW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01844 1423767.BALU01000003_gene1092 6.57e-175 499.0 29DXA@1|root,300V7@2|Bacteria,1U59E@1239|Firmicutes,4IF0P@91061|Bacilli,3F59A@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP AGEJAFOK_01845 1033837.WANG_1620 1.14e-154 447.0 29DXA@1|root,300V7@2|Bacteria,1U59E@1239|Firmicutes,4IF0P@91061|Bacilli,3F59A@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - - AGEJAFOK_01846 525365.HMPREF0548_1861 1.06e-133 389.0 29NJD@1|root,309JD@2|Bacteria,1U580@1239|Firmicutes,4IEZA@91061|Bacilli,3F53B@33958|Lactobacillaceae 91061|Bacilli S Bacteriocin helveticin-J - - - - - - - - - - - - Helveticin_J AGEJAFOK_01847 525365.HMPREF0548_1860 2.35e-58 181.0 29P23@1|root,30A09@2|Bacteria,1U60S@1239|Firmicutes,4IFPI@91061|Bacilli,3F6ST@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01848 525365.HMPREF0548_1858 8.29e-76 227.0 COG1396@1|root,COG1396@2|Bacteria,1VEP9@1239|Firmicutes,4HPCR@91061|Bacilli,3F871@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_26,HTH_3 AGEJAFOK_01849 405566.lhv_0083 1.98e-41 141.0 COG2856@1|root,COG2856@2|Bacteria,1W1K0@1239|Firmicutes,4IGCD@91061|Bacilli,3F81Z@33958|Lactobacillaceae 91061|Bacilli E Zn peptidase - - - - - - - - - - - - Peptidase_M48,Peptidase_M78 AGEJAFOK_01850 748671.LCRIS_02016 0.0 989.0 COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F3MU@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC AGEJAFOK_01851 748671.LCRIS_01685 0.0 969.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HIAU@91061|Bacilli,3F3JJ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran AGEJAFOK_01852 748671.LCRIS_01686 1.28e-228 628.0 COG2267@1|root,COG2267@2|Bacteria,1UEDT@1239|Firmicutes,4HF61@91061|Bacilli,3F47H@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepR - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 AGEJAFOK_01853 748671.LCRIS_01687 1.75e-168 471.0 COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,4HUBD@91061|Bacilli,3FC94@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C AGEJAFOK_01854 748671.LCRIS_01688 2.37e-242 675.0 COG5002@1|root,COG5002@2|Bacteria,1V5MM@1239|Firmicutes,4ISZN@91061|Bacilli,3FBU1@33958|Lactobacillaceae 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA AGEJAFOK_01855 748671.LCRIS_01689 2.88e-98 288.0 COG3212@1|root,COG3212@2|Bacteria,1VEU1@1239|Firmicutes,4HPJK@91061|Bacilli,3F6RU@33958|Lactobacillaceae 91061|Bacilli S Peptidase propeptide and YPEB domain ykoJ - - - - - - - - - - - PepSY AGEJAFOK_01856 748671.LCRIS_01690 5.59e-109 317.0 COG3212@1|root,COG3212@2|Bacteria,1VD0Q@1239|Firmicutes,4IPQG@91061|Bacilli,3FBE6@33958|Lactobacillaceae 91061|Bacilli S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY AGEJAFOK_01857 748671.LCRIS_01691 8e-108 312.0 COG0454@1|root,COG0456@2|Bacteria,1VDFK@1239|Firmicutes,4HMHW@91061|Bacilli,3FB81@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain XK27_03150 - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 AGEJAFOK_01858 748671.LCRIS_01692 8.64e-85 252.0 COG1846@1|root,COG1846@2|Bacteria,1V3PS@1239|Firmicutes,4HFN6@91061|Bacilli,3F6VT@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator yybA - - - - - - - - - - - MarR AGEJAFOK_01859 324831.LGAS_0437 2.91e-83 262.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F4EQ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AGEJAFOK_01860 324831.LGAS_0437 1.13e-201 572.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F4EQ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AGEJAFOK_01861 748671.LCRIS_00699 4.76e-168 471.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,3F4P1@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 AGEJAFOK_01862 748671.LCRIS_00698 3.16e-144 407.0 COG4619@1|root,COG4619@2|Bacteria,1V3DQ@1239|Firmicutes,4HHGU@91061|Bacilli,3F4UY@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ybbL - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran AGEJAFOK_01863 748671.LCRIS_00697 0.0 1094.0 2FIUN@1|root,34AK2@2|Bacteria,1W1FZ@1239|Firmicutes,4HYXZ@91061|Bacilli,3F4QV@33958|Lactobacillaceae 91061|Bacilli S SH3-like domain - - - - - - - - - - - - Big_3,SH3_8 AGEJAFOK_01864 1423748.BALB01000001_gene167 1.16e-128 366.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,3F3M0@33958|Lactobacillaceae 91061|Bacilli O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease AGEJAFOK_01865 748671.LCRIS_00695 8.59e-221 609.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,3F4AB@33958|Lactobacillaceae 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N AGEJAFOK_01866 748671.LCRIS_00694 2.78e-251 689.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,3F4D5@33958|Lactobacillaceae 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 AGEJAFOK_01867 748671.LCRIS_00693 2.44e-211 583.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,3F4NY@33958|Lactobacillaceae 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 AGEJAFOK_01868 748671.LCRIS_00692 1.55e-117 337.0 COG3247@1|root,COG3247@2|Bacteria,1V759@1239|Firmicutes,4HK5F@91061|Bacilli,3F58J@33958|Lactobacillaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 AGEJAFOK_01869 748671.LCRIS_00691 0.0 1866.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,3F4TZ@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran AGEJAFOK_01870 748671.LCRIS_00690 0.0 1305.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,3F3XM@33958|Lactobacillaceae 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB AGEJAFOK_01871 748671.LCRIS_00689 0.0 1142.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,3F457@33958|Lactobacillaceae 91061|Bacilli G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV AGEJAFOK_01872 748671.LCRIS_00688 3.42e-232 638.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,3F411@33958|Lactobacillaceae 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 AGEJAFOK_01873 748671.LCRIS_00687 3.31e-239 658.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,3F4C8@33958|Lactobacillaceae 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N AGEJAFOK_01874 748671.LCRIS_00686 4.04e-203 561.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,3F42N@33958|Lactobacillaceae 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT AGEJAFOK_01875 748671.LCRIS_00685 3.54e-230 634.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,3F3Z3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N AGEJAFOK_01876 748671.LCRIS_00684 8.33e-27 100.0 29P93@1|root,30A77@2|Bacteria,1U6A5@1239|Firmicutes,4IG1D@91061|Bacilli,3F7F0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01877 748671.LCRIS_00683 2.24e-238 655.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,3F3SN@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 AGEJAFOK_01878 748671.LCRIS_00682 0.0 1546.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,3F4DH@33958|Lactobacillaceae 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW AGEJAFOK_01879 326425.lhe_0686 1.55e-122 350.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,3F40M@33958|Lactobacillaceae 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE AGEJAFOK_01880 748671.LCRIS_00680 9.44e-169 471.0 COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli,3F714@33958|Lactobacillaceae 91061|Bacilli S Competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran AGEJAFOK_01881 748671.LCRIS_00679 2.68e-314 855.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli,3F3TQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII AGEJAFOK_01882 748671.LCRIS_00678 5.04e-154 432.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,3F3SQ@33958|Lactobacillaceae 91061|Bacilli S YigZ family yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 AGEJAFOK_01883 748671.LCRIS_00677 1.94e-268 736.0 COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,3F4JV@33958|Lactobacillaceae 91061|Bacilli M transferase tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 AGEJAFOK_01884 748671.LCRIS_00676 3.03e-293 812.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,3F3WX@33958|Lactobacillaceae 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 AGEJAFOK_01885 748671.LCRIS_00674 1.17e-248 684.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA AGEJAFOK_01886 748671.LCRIS_00673 3.92e-123 352.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,3F4BI@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf AGEJAFOK_01887 748671.LCRIS_00672 1.63e-154 445.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,3F3SM@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 AGEJAFOK_01888 748671.LCRIS_00671 3.27e-170 475.0 COG1028@1|root,COG1028@2|Bacteria,1V0YW@1239|Firmicutes,4ISGK@91061|Bacilli,3FBEA@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 AGEJAFOK_01889 748671.LCRIS_00670 5.49e-301 820.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,3F4MU@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C AGEJAFOK_01890 748671.LCRIS_00669 1.47e-284 778.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,3F3SA@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 inactive domain protein ymfF - - - - - - - - - - - Peptidase_M16_C AGEJAFOK_01891 748671.LCRIS_00668 0.0 1516.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,3F3JZ@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma AGEJAFOK_01892 748671.LCRIS_00667 3.12e-91 266.0 COG4835@1|root,COG4835@2|Bacteria,1VJ7H@1239|Firmicutes,4HP0P@91061|Bacilli,3F6JB@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1149) - - - - - - - - - - - - DUF1149 AGEJAFOK_01893 748671.LCRIS_00666 2.12e-136 385.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,3F42Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase AGEJAFOK_01894 748671.LCRIS_00665 2.19e-270 741.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter XK27_05220 - - - - - - - - - - - AI-2E_transport AGEJAFOK_01895 748671.LCRIS_00664 1.99e-87 256.0 COG3731@1|root,COG3731@2|Bacteria,1VGKB@1239|Firmicutes,4HNJN@91061|Bacilli,3F8EZ@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component srlB - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA AGEJAFOK_01896 748671.LCRIS_00663 1.01e-255 700.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,3F3RC@33958|Lactobacillaceae 91061|Bacilli G Lactonase, 7-bladed beta-propeller pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase AGEJAFOK_01897 891391.LAC30SC_03265 3.77e-122 353.0 COG0398@1|root,COG0398@2|Bacteria,1V6V7@1239|Firmicutes,4HITM@91061|Bacilli,3F417@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc AGEJAFOK_01898 748671.LCRIS_00661 0.0 1209.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,3F3QX@33958|Lactobacillaceae 91061|Bacilli S Myosin-crossreactive antigen mycA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA AGEJAFOK_01899 748671.LCRIS_00660 7.96e-221 608.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F46Z@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD2 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 AGEJAFOK_01900 748671.LCRIS_00659 1.91e-195 541.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,3F45D@33958|Lactobacillaceae 91061|Bacilli F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase AGEJAFOK_01901 748671.LCRIS_00658 1.7e-147 415.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,3F452@33958|Lactobacillaceae 91061|Bacilli S RelA SpoT domain protein yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT AGEJAFOK_01902 748671.LCRIS_00657 2.44e-143 404.0 COG4116@1|root,COG4116@2|Bacteria,1TTVM@1239|Firmicutes,4I4A3@91061|Bacilli,3F4YS@33958|Lactobacillaceae 91061|Bacilli S CYTH - - - - - - - - - - - - CYTH AGEJAFOK_01903 748671.LCRIS_00656 5.74e-148 416.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,3F6QR@33958|Lactobacillaceae 91061|Bacilli Q Thioredoxin yjbH - - - - - - - - - - - Thioredoxin_5 AGEJAFOK_01904 748671.LCRIS_00655 2.63e-205 567.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,3F4BZ@33958|Lactobacillaceae 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA AGEJAFOK_01905 748671.LCRIS_00654 1.5e-178 497.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli,3F5G4@33958|Lactobacillaceae 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA AGEJAFOK_01906 1423767.BALU01000014_gene26 6.28e-87 256.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F6HJ@33958|Lactobacillaceae 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC AGEJAFOK_01907 748671.LCRIS_00652 0.0 1125.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,3F3MS@33958|Lactobacillaceae 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C AGEJAFOK_01908 1423748.BALB01000004_gene612 1.29e-54 171.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,3F6XQ@33958|Lactobacillaceae 91061|Bacilli G phosphocarrier protein HPR ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr AGEJAFOK_01909 748671.LCRIS_00650 2.6e-37 125.0 29PIA@1|root,30AGF@2|Bacteria,1U6MM@1239|Firmicutes,4IGEE@91061|Bacilli,3F85J@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01910 748671.LCRIS_01654 1.38e-165 520.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - DUF285,GbpC,Gram_pos_anchor,YSIRK_signal AGEJAFOK_01911 748671.LCRIS_01654 9.06e-184 577.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - DUF285,GbpC,Gram_pos_anchor,YSIRK_signal AGEJAFOK_01912 748671.LCRIS_01654 1.44e-53 187.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - DUF285,GbpC,Gram_pos_anchor,YSIRK_signal AGEJAFOK_01913 748671.LCRIS_01654 4.98e-37 141.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - DUF285,GbpC,Gram_pos_anchor,YSIRK_signal AGEJAFOK_01914 748671.LCRIS_01655 0.0 871.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,3F3M6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b AGEJAFOK_01915 748671.LCRIS_01656 1.23e-129 368.0 COG1670@1|root,COG1670@2|Bacteria,1V49W@1239|Firmicutes,4HHAP@91061|Bacilli,3F5A6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yjcK - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 AGEJAFOK_01916 748671.LCRIS_01657 3.2e-143 404.0 COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,4HIU5@91061|Bacilli,3F3SV@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc AGEJAFOK_01917 748671.LCRIS_01658 2.52e-194 538.0 COG0657@1|root,COG0657@2|Bacteria,1VEC5@1239|Firmicutes,4HKY6@91061|Bacilli,3F50A@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 AGEJAFOK_01918 748671.LCRIS_01659 1.15e-201 558.0 COG1396@1|root,COG1396@2|Bacteria,1VBK2@1239|Firmicutes,4HCZ9@91061|Bacilli,3FBE7@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix plcR - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,TPR_12,TPR_8 AGEJAFOK_01919 1423754.BALY01000017_gene389 9.75e-20 88.6 COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae 91061|Bacilli S cog cog1373 - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 AGEJAFOK_01920 748671.LCRIS_00482 1.08e-145 410.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,3F59K@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac AGEJAFOK_01921 748671.LCRIS_00481 3.31e-79 236.0 COG3223@1|root,COG3223@2|Bacteria,1VIFW@1239|Firmicutes,4IRYI@91061|Bacilli,3F6MF@33958|Lactobacillaceae 91061|Bacilli S Phosphate-starvation-inducible E psiE - - ko:K13256 - - - - ko00000 - - - PsiE AGEJAFOK_01923 891391.LAC30SC_02460 6.58e-175 488.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,3F4IY@33958|Lactobacillaceae 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase AGEJAFOK_01924 1423767.BALU01000012_gene156 1.49e-290 794.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,3F3X1@33958|Lactobacillaceae 91061|Bacilli P ammonium transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp AGEJAFOK_01925 1423767.BALU01000012_gene155 7.82e-80 237.0 29P2Q@1|root,30A0W@2|Bacteria,1U61M@1239|Firmicutes,4IFQH@91061|Bacilli,3F6U2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01926 1423767.BALU01000012_gene154 0.0 1498.0 COG1201@1|root,COG1201@2|Bacteria,1UHYQ@1239|Firmicutes,4HD4E@91061|Bacilli,3F42E@33958|Lactobacillaceae 91061|Bacilli L DEAD DEAH box helicase - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C AGEJAFOK_01927 1423767.BALU01000012_gene153 2.14e-312 852.0 COG1135@1|root,COG1135@2|Bacteria,1TQPH@1239|Firmicutes,4HCUW@91061|Bacilli,3F54M@33958|Lactobacillaceae 91061|Bacilli P P-loop Domain of unknown function (DUF2791) - - - - - - - - - - - - DUF2791 AGEJAFOK_01928 748671.LCRIS_00476 5.53e-173 497.0 28PUF@1|root,2ZCFF@2|Bacteria,1V2H3@1239|Firmicutes,4HRKS@91061|Bacilli,3F3KN@33958|Lactobacillaceae 91061|Bacilli S TerB-C domain - - - - - - - - - - - - TerB_C,TerB_N AGEJAFOK_01929 1125699.HMPREF9194_00053 5.32e-35 132.0 COG1018@1|root,COG1018@2|Bacteria 2|Bacteria C nitric oxide dioxygenase activity - - - ko:K21832 - - - - ko00000 - - - FAD_binding_6,Fer2,NAD_binding_1 AGEJAFOK_01930 257314.LJ_1138 4.43e-179 499.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,3F3XT@33958|Lactobacillaceae 91061|Bacilli O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran AGEJAFOK_01931 257314.LJ_1139 6.22e-232 645.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,3F4BR@33958|Lactobacillaceae 91061|Bacilli O FeS assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 AGEJAFOK_01932 257314.LJ_1140 1.39e-224 627.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,3F3UP@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 AGEJAFOK_01933 257314.LJ_1141 6.98e-78 234.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,3F6WP@33958|Lactobacillaceae 91061|Bacilli C SUF system FeS assembly protein, NifU family nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N AGEJAFOK_01934 257314.LJ_1142 0.0 920.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,3F44I@33958|Lactobacillaceae 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 AGEJAFOK_01935 257314.LJ_1143 8.12e-60 185.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - FeS_assembly_P AGEJAFOK_01936 257314.LJ_1144 1.27e-311 855.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp AGEJAFOK_01937 748671.LCRIS_00632 4.42e-269 754.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli,3F425@33958|Lactobacillaceae 91061|Bacilli I Hydroxymethylglutaryl-CoA synthase mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N AGEJAFOK_01938 748671.LCRIS_00630 1.22e-272 746.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,3F3Q5@33958|Lactobacillaceae 91061|Bacilli I Belongs to the thiolase family atoB - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red,Thiolase_C,Thiolase_N AGEJAFOK_01939 748671.LCRIS_00629 3.22e-215 594.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,3F45A@33958|Lactobacillaceae 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase AGEJAFOK_01940 748671.LCRIS_00628 1.4e-208 578.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,3F4TC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0761 family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB AGEJAFOK_01941 748671.LCRIS_00627 9.98e-211 580.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,3F3MK@33958|Lactobacillaceae 91061|Bacilli E Methionine Aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 AGEJAFOK_01942 748671.LCRIS_00626 5.14e-105 303.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli,3F6HY@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin ykuP - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 AGEJAFOK_01943 748671.LCRIS_00625 7.46e-113 325.0 COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,3F4GH@33958|Lactobacillaceae 91061|Bacilli S Teichoic acid glycosylation protein gtcA1 - - - - - - - - - - - GtrA AGEJAFOK_01944 748671.LCRIS_00940 1.07e-153 431.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,3F4BS@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain yjhB - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,Nudix_N AGEJAFOK_01945 748671.LCRIS_00941 1.28e-310 848.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans AGEJAFOK_01946 748671.LCRIS_00942 0.0 1120.0 COG4974@1|root,COG4974@2|Bacteria,1V2WH@1239|Firmicutes,4IRAD@91061|Bacilli,3FBND@33958|Lactobacillaceae 91061|Bacilli L Plasmid pRiA4b ORF-3-like protein - - - - - - - - - - - - PRiA4_ORF3 AGEJAFOK_01947 324831.LGAS_0952 3.77e-86 253.0 COG1733@1|root,COG1733@2|Bacteria,1V707@1239|Firmicutes,4IFCB@91061|Bacilli,3F673@33958|Lactobacillaceae 91061|Bacilli K HxlR family - - - - - - - - - - - - HxlR AGEJAFOK_01948 324831.LGAS_0953 9.35e-63 192.0 2CTS0@1|root,32SU1@2|Bacteria,1VAN9@1239|Firmicutes,4IFW5@91061|Bacilli,3F75U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01949 324831.LGAS_0954 2.1e-270 741.0 COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,3F5KM@33958|Lactobacillaceae 91061|Bacilli M Mandelate racemase muconate lactonizing enzyme dgoD - 4.2.1.6,4.2.1.8 ko:K01684,ko:K08323 ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120 M00061,M00552 R03033,R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N AGEJAFOK_01950 748671.LCRIS_00943 1.44e-80 241.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,3F5VY@33958|Lactobacillaceae 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin AGEJAFOK_01952 390333.Ldb1396 5.74e-69 229.0 2DZDR@1|root,32V81@2|Bacteria,1V5XJ@1239|Firmicutes,4HKPG@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01953 1545702.LACWKB8_1708 7.51e-174 492.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4HFJ8@91061|Bacilli,3FC5I@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 AGEJAFOK_01954 1545702.LACWKB8_1709 1.14e-143 408.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,3F5F6@33958|Lactobacillaceae 91061|Bacilli H Transaldolase/Fructose-6-phosphate aldolase tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA AGEJAFOK_01955 1545702.LACWKB8_1710 0.0 932.0 COG3715@1|root,COG3716@1|root,COG3715@2|Bacteria,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4IQMA@91061|Bacilli,3F5AX@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - - - - - - - - - - EII-Sor,EIID-AGA AGEJAFOK_01956 1545702.LACWKB8_1711 3.59e-69 211.0 COG2893@1|root,COG2893@2|Bacteria,1VCJ2@1239|Firmicutes,4HPXK@91061|Bacilli,3F7TA@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man AGEJAFOK_01957 1545702.LACWKB8_1712 5.36e-100 291.0 COG3444@1|root,COG3444@2|Bacteria,1V5VV@1239|Firmicutes,4HVJT@91061|Bacilli,3F67C@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb AGEJAFOK_01959 748671.LCRIS_00173 2.85e-54 172.0 29QPJ@1|root,30BP9@2|Bacteria,1U8EN@1239|Firmicutes,4IICH@91061|Bacilli,3FAWE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01960 748671.LCRIS_00174 8.49e-100 291.0 COG1595@1|root,COG1595@2|Bacteria,1U6KG@1239|Firmicutes,4IGD9@91061|Bacilli,3F83H@33958|Lactobacillaceae 91061|Bacilli K DNA-templated transcription, initiation - - - - - - - - - - - - Sigma70_r4 AGEJAFOK_01962 748671.LCRIS_00176 5.32e-190 530.0 COG5464@1|root,COG5464@2|Bacteria,1V1A7@1239|Firmicutes,4HG0B@91061|Bacilli,3F655@33958|Lactobacillaceae 91061|Bacilli S PD-(D/E)XK nuclease family transposase - - - - - - - - - - - - PDDEXK_2 AGEJAFOK_01963 748671.LCRIS_00176 6.87e-27 105.0 COG5464@1|root,COG5464@2|Bacteria,1V1A7@1239|Firmicutes,4HG0B@91061|Bacilli,3F655@33958|Lactobacillaceae 91061|Bacilli S PD-(D/E)XK nuclease family transposase - - - - - - - - - - - - PDDEXK_2 AGEJAFOK_01964 326425.lhe_0185 4.54e-135 402.0 2DHS4@1|root,300QQ@2|Bacteria,1U572@1239|Firmicutes,4IEYM@91061|Bacilli,3F4ZW@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - GO:0005575,GO:0005623,GO:0030115,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - SLAP AGEJAFOK_01965 748671.LCRIS_00170 1.05e-54 171.0 2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,4HRAS@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2922) - - - - - - - - - - - - DUF2922 AGEJAFOK_01966 748671.LCRIS_00169 1.21e-40 134.0 2AQKB@1|root,31FT9@2|Bacteria,1U6IH@1239|Firmicutes,4IGAU@91061|Bacilli,3F7ZB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_01967 1545702.LACWKB8_0106 2.5e-136 392.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,3F4PC@33958|Lactobacillaceae 91061|Bacilli S Nitronate monooxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO AGEJAFOK_01968 97137.C821_01885 8.45e-102 308.0 COG4670@1|root,COG4670@2|Bacteria,1TP5H@1239|Firmicutes,4IS4T@91061|Bacilli,3F5QE@33958|Lactobacillaceae 91061|Bacilli I Coenzyme A transferase pct - 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 - R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans AGEJAFOK_01969 97137.C821_01885 4.12e-205 578.0 COG4670@1|root,COG4670@2|Bacteria,1TP5H@1239|Firmicutes,4IS4T@91061|Bacilli,3F5QE@33958|Lactobacillaceae 91061|Bacilli I Coenzyme A transferase pct - 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 - R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans AGEJAFOK_01970 97137.C821_01886 5.38e-184 515.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HB94@91061|Bacilli,3F4UJ@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate AGEJAFOK_01971 97137.C821_01887 1.47e-70 217.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,3F6YS@33958|Lactobacillaceae 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like AGEJAFOK_01972 97137.C821_01888 1.41e-97 288.0 COG4684@1|root,COG4684@2|Bacteria,1V2ZW@1239|Firmicutes,4IR4I@91061|Bacilli,3FBM9@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt AGEJAFOK_01973 326425.lhe_0455 3.28e-101 306.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli,3F42Q@33958|Lactobacillaceae 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK AGEJAFOK_01974 324831.LGAS_0706 1.29e-41 141.0 COG1765@1|root,COG1765@2|Bacteria,1VN90@1239|Firmicutes,4HRIC@91061|Bacilli,3F6MQ@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC AGEJAFOK_01976 326425.lhe_1384 1.33e-44 159.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 AGEJAFOK_01978 748671.LCRIS_01491 4.87e-81 239.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,3F7FK@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family yodB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR AGEJAFOK_01979 748671.LCRIS_01492 3.23e-172 481.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,3F3NF@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind AGEJAFOK_01980 748671.LCRIS_01493 5.58e-59 182.0 COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli,3F81R@33958|Lactobacillaceae 91061|Bacilli C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020 Acylphosphatase AGEJAFOK_01981 748671.LCRIS_01494 2.43e-216 598.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,3F3P3@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP AGEJAFOK_01982 748671.LCRIS_01495 2.08e-95 280.0 COG3760@1|root,COG3760@2|Bacteria,1V29H@1239|Firmicutes,4HP8F@91061|Bacilli,3F6ZD@33958|Lactobacillaceae 91061|Bacilli S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit AGEJAFOK_01983 525365.HMPREF0548_1157 2.42e-69 223.0 2BSQ8@1|root,32MT2@2|Bacteria,1UPRG@1239|Firmicutes,4IV9J@91061|Bacilli,3F7BK@33958|Lactobacillaceae 91061|Bacilli S Abi-like protein - - - - - - - - - - - - Abi_2 AGEJAFOK_01984 748671.LCRIS_01496 7.24e-284 775.0 29V6Q@1|root,30GKE@2|Bacteria,1UG8H@1239|Firmicutes,4IF4J@91061|Bacilli,3F5M6@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP AGEJAFOK_01985 891391.LAC30SC_10545 9.04e-162 468.0 COG1266@1|root,COG1266@2|Bacteria,1VNA9@1239|Firmicutes,4HRMP@91061|Bacilli,3F5T9@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi AGEJAFOK_01986 748671.LCRIS_01306 5.41e-172 480.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F3MG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein cysA - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AGEJAFOK_01987 748671.LCRIS_01305 0.0 1135.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4HAZG@91061|Bacilli,3F45H@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX AGEJAFOK_01988 748671.LCRIS_01304 0.0 898.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA32@91061|Bacilli,3FCAJ@33958|Lactobacillaceae 91061|Bacilli E amino acid ctrA - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 AGEJAFOK_01989 748671.LCRIS_01303 5.56e-72 216.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,3F7FG@33958|Lactobacillaceae 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 AGEJAFOK_01990 748671.LCRIS_01302 1.34e-289 797.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,3F40R@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB AGEJAFOK_01991 272621.LBA1289 6.78e-60 184.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 AGEJAFOK_01992 748671.LCRIS_01300 2.08e-122 348.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,3F74P@33958|Lactobacillaceae 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM AGEJAFOK_01993 748671.LCRIS_01299 1.63e-173 483.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,3F3NP@33958|Lactobacillaceae 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT AGEJAFOK_01994 748671.LCRIS_01298 1.64e-74 223.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,3F6K4@33958|Lactobacillaceae 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 AGEJAFOK_01995 748671.LCRIS_01297 4.96e-270 739.0 29V6Q@1|root,30GKE@2|Bacteria,1UG8H@1239|Firmicutes,4IF4J@91061|Bacilli,3F5M6@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP AGEJAFOK_01996 748671.LCRIS_01296 1.15e-154 434.0 COG1573@1|root,COG1573@2|Bacteria,1V4M9@1239|Firmicutes,4HHJN@91061|Bacilli,3F4GW@33958|Lactobacillaceae 91061|Bacilli L Uracil-DNA glycosylase ung2 - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG AGEJAFOK_01997 748671.LCRIS_01295 7.18e-187 519.0 COG2755@1|root,COG2755@2|Bacteria,1V4VT@1239|Firmicutes,4HXCK@91061|Bacilli,3F4P8@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 AGEJAFOK_01998 748671.LCRIS_01294 9.86e-146 410.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3F3JG@33958|Lactobacillaceae 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 AGEJAFOK_01999 748671.LCRIS_01293 4.16e-51 162.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,3F87S@33958|Lactobacillaceae 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 AGEJAFOK_02000 405566.lhv_1362 1.3e-40 134.0 COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HKMJ@91061|Bacilli,3F809@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0154) XK26_06720 - - ko:K09976 - - - - ko00000 - - - UPF0154 AGEJAFOK_02001 748671.LCRIS_01291 0.0 1126.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran AGEJAFOK_02002 748671.LCRIS_01290 0.0 1134.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AGEJAFOK_02003 748671.LCRIS_01289 0.0 1295.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F4CX@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N AGEJAFOK_02004 748671.LCRIS_01288 1.74e-295 805.0 COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,4HDKI@91061|Bacilli,3F3PA@33958|Lactobacillaceae 91061|Bacilli M cyclopropane-fatty-acyl-phospholipid synthase cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS AGEJAFOK_02005 748671.LCRIS_01287 1.65e-151 425.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,3F4QB@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase AGEJAFOK_02006 748671.LCRIS_01286 2.03e-251 689.0 COG2827@1|root,COG4123@1|root,COG2827@2|Bacteria,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,3F4C5@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase small domain yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS AGEJAFOK_02007 748671.LCRIS_01285 2.21e-180 502.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3F3M1@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 AGEJAFOK_02008 748671.LCRIS_01284 1.76e-235 649.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,3F459@33958|Lactobacillaceae 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS AGEJAFOK_02009 748671.LCRIS_01283 5.86e-168 469.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,3F42J@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase AGEJAFOK_02010 748671.LCRIS_01282 1.22e-121 348.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,3F4X2@33958|Lactobacillaceae 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF AGEJAFOK_02011 748671.LCRIS_01281 6.38e-178 495.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,3F42M@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf AGEJAFOK_02012 272621.LBA1265 3.93e-181 505.0 COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,4IV81@91061|Bacilli,3F4AF@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 AGEJAFOK_02013 748671.LCRIS_01279 6.38e-254 702.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,3F3TM@33958|Lactobacillaceae 91061|Bacilli M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 AGEJAFOK_02014 748671.LCRIS_01278 0.0 1117.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,3F44A@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit AGEJAFOK_02015 748671.LCRIS_01277 0.0 2886.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,3F4AN@33958|Lactobacillaceae 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon AGEJAFOK_02016 748671.LCRIS_01276 3.4e-108 311.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,3F6GZ@33958|Lactobacillaceae 91061|Bacilli J Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C AGEJAFOK_02017 748671.LCRIS_01275 1.19e-259 714.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,3F3KZ@33958|Lactobacillaceae 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 AGEJAFOK_02018 748671.LCRIS_01274 3.75e-63 193.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,3F7E2@33958|Lactobacillaceae 91061|Bacilli K Protein of unknown function (DUF448) ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 AGEJAFOK_02019 748671.LCRIS_01273 1.61e-64 197.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,3F7ZK@33958|Lactobacillaceae 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae AGEJAFOK_02020 748671.LCRIS_01272 0.0 1507.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,3F3JV@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N AGEJAFOK_02021 748671.LCRIS_01271 1.67e-79 236.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,3F6WZ@33958|Lactobacillaceae 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA AGEJAFOK_02022 748671.LCRIS_01270 1.64e-198 551.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,3F3NX@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N AGEJAFOK_02023 748671.LCRIS_01269 5.35e-223 615.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,3F3TG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase AGEJAFOK_02024 748671.LCRIS_01268 6.02e-247 678.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,3F3ST@33958|Lactobacillaceae 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg AGEJAFOK_02025 748671.LCRIS_01267 3.74e-109 317.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,3F4DY@33958|Lactobacillaceae 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE AGEJAFOK_02026 748671.LCRIS_01266 0.0 1134.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,3F48C@33958|Lactobacillaceae 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 AGEJAFOK_02027 748671.LCRIS_01265 6.87e-277 757.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,3F490@33958|Lactobacillaceae 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG AGEJAFOK_02028 891391.LAC30SC_06980 0.0 1199.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,3F3Z1@33958|Lactobacillaceae 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C AGEJAFOK_02029 525365.HMPREF0548_0109 7e-131 375.0 COG3764@1|root,COG3764@2|Bacteria,1V83Z@1239|Firmicutes,4HJV9@91061|Bacilli,3F54V@33958|Lactobacillaceae 91061|Bacilli M sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase AGEJAFOK_02030 748671.LCRIS_01261 0.0 1415.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,3F42C@33958|Lactobacillaceae 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C AGEJAFOK_02031 748671.LCRIS_01260 1.15e-121 347.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,3F4DB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran AGEJAFOK_02032 748671.LCRIS_00566 1.22e-192 540.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9UE@91061|Bacilli,3FCA7@33958|Lactobacillaceae 91061|Bacilli EGP MFS_1 like family pmrA - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr AGEJAFOK_02033 405566.lhv_1637 3.98e-97 288.0 COG1388@1|root,COG1388@2|Bacteria,1U652@1239|Firmicutes,4IFUT@91061|Bacilli,3F72G@33958|Lactobacillaceae 91061|Bacilli M LysM domain - - - - - - - - - - - - - AGEJAFOK_02034 891391.LAC30SC_00325 3.3e-42 149.0 29NRE@1|root,309PD@2|Bacteria,1U5FQ@1239|Firmicutes,4IF74@91061|Bacilli,3F5V7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02036 748671.LCRIS_01612 2.58e-45 151.0 29NRE@1|root,309PD@2|Bacteria,1U5FQ@1239|Firmicutes,4IF74@91061|Bacilli,3F5V7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02037 891391.LAC30SC_08615 1.38e-95 291.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 AGEJAFOK_02038 891391.LAC30SC_03550 9.16e-301 822.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon AGEJAFOK_02039 891391.LAC30SC_08615 1.48e-139 406.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 AGEJAFOK_02040 1033837.WANG_1534 1.08e-161 461.0 COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae 91061|Bacilli S cog cog1373 - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 AGEJAFOK_02042 1034809.SLUG_00340 5.94e-100 302.0 COG1073@1|root,COG1073@2|Bacteria,1UZH6@1239|Firmicutes,4IQYC@91061|Bacilli 91061|Bacilli S X-Pro dipeptidyl-peptidase (S15 family) - - - ko:K06889 - - - - ko00000 - - - DLH AGEJAFOK_02043 1536772.R70723_11830 2.25e-57 186.0 COG1309@1|root,COG1309@2|Bacteria,1VBY5@1239|Firmicutes,4HNRX@91061|Bacilli,26YKV@186822|Paenibacillaceae 91061|Bacilli K Tetracycline repressor, C-terminal all-alpha domain - - - - - - - - - - - - TetR_C_10,TetR_N AGEJAFOK_02045 1423775.BAMN01000002_gene2088 3.49e-113 335.0 COG0583@1|root,COG0583@2|Bacteria,1TT5B@1239|Firmicutes,4HK1M@91061|Bacilli,3F5CC@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate AGEJAFOK_02046 1136177.KCA1_2581 1.59e-44 148.0 2DPB1@1|root,331BT@2|Bacteria,1UJ8M@1239|Firmicutes,4IT4I@91061|Bacilli,3FBUN@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 AGEJAFOK_02047 220668.lp_2872 8.27e-88 263.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HGYK@91061|Bacilli,3F60E@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 AGEJAFOK_02048 1423724.BAMM01000001_gene94 1.64e-169 480.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F42F@33958|Lactobacillaceae 91061|Bacilli E alcohol dehydrogenase adh2 - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N AGEJAFOK_02049 445961.IW15_19790 1.44e-62 203.0 COG4221@1|root,COG4221@2|Bacteria,4NHY6@976|Bacteroidetes,1I2FY@117743|Flavobacteriia,3ZQ92@59732|Chryseobacterium 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short AGEJAFOK_02050 324831.LGAS_1678 4.85e-93 276.0 COG1737@1|root,COG1737@2|Bacteria,1TR75@1239|Firmicutes,4HJU7@91061|Bacilli,3F6Y6@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS AGEJAFOK_02051 324831.LGAS_1678 1.91e-28 107.0 COG1737@1|root,COG1737@2|Bacteria,1TR75@1239|Firmicutes,4HJU7@91061|Bacilli,3F6Y6@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS AGEJAFOK_02052 1121864.OMO_02339 1.52e-105 309.0 COG2256@1|root,COG2256@2|Bacteria,1TXDS@1239|Firmicutes,4HEXN@91061|Bacilli,4B0NA@81852|Enterococcaceae 91061|Bacilli L MgsA AAA+ ATPase C terminal - - - - - - - - - - - - MgsA_C AGEJAFOK_02053 324831.LGAS_1676 2.53e-287 788.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F54Z@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane lacE - 2.7.1.207 ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 - - PTS_EIIC,PTS_IIB AGEJAFOK_02055 748671.LCRIS_01717 2.77e-135 382.0 COG0454@1|root,COG0456@2|Bacteria,1V7GR@1239|Firmicutes,4HJ11@91061|Bacilli,3F44B@33958|Lactobacillaceae 91061|Bacilli K acetyltransferase - - - ko:K06977 - - - - ko00000 - - - Acetyltransf_1 AGEJAFOK_02056 748671.LCRIS_01716 5.45e-121 345.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,3F3K3@33958|Lactobacillaceae 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran AGEJAFOK_02057 748671.LCRIS_01641 7.25e-309 843.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,3F4MJ@33958|Lactobacillaceae 91061|Bacilli C ubiquinol oxidase cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I AGEJAFOK_02058 748671.LCRIS_01640 9.83e-236 649.0 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,3F40S@33958|Lactobacillaceae 91061|Bacilli C Cytochrome d ubiquinol oxidase subunit II cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iYO844.BSU38750 Cyt_bd_oxida_II AGEJAFOK_02059 748671.LCRIS_01639 0.0 1082.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HAN0@91061|Bacilli,3F451@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD cydC GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran AGEJAFOK_02060 1423748.BALB01000003_gene440 0.0 929.0 COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4HAAB@91061|Bacilli,3F4PG@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC cydD - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran AGEJAFOK_02061 748671.LCRIS_01636 1.44e-164 460.0 COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HJYK@91061|Bacilli,3FC67@33958|Lactobacillaceae 91061|Bacilli H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_25,Ubie_methyltran AGEJAFOK_02062 748671.LCRIS_01140 3.35e-269 738.0 COG3757@1|root,COG3757@2|Bacteria,1VF8D@1239|Firmicutes,4HX0U@91061|Bacilli,3F4U9@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,LysM,SH3_5,SLAP AGEJAFOK_02063 748671.LCRIS_01139 4.36e-142 401.0 29N5D@1|root,30939@2|Bacteria,1V5Q4@1239|Firmicutes,4HHUF@91061|Bacilli,3F5S8@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF5052) XK27_00160 - - - - - - - - - - - DUF5052 AGEJAFOK_02064 748671.LCRIS_01138 1.5e-90 266.0 29EME@1|root,301JC@2|Bacteria,1U5N3@1239|Firmicutes,4IFCU@91061|Bacilli,3F67R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02065 748671.LCRIS_01137 1.24e-258 708.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HANE@91061|Bacilli,3F3P9@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family xerS - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase AGEJAFOK_02066 748671.LCRIS_01135 0.0 1051.0 COG1193@1|root,COG1193@2|Bacteria,1TQWB@1239|Firmicutes,4HAHW@91061|Bacilli,3F47G@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS1 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V AGEJAFOK_02067 748671.LCRIS_00110 3.19e-165 461.0 COG0596@1|root,COG0596@2|Bacteria,1TSFW@1239|Firmicutes,4HI0M@91061|Bacilli,3F5BW@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 AGEJAFOK_02068 748671.LCRIS_00109 6.44e-200 553.0 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HNAP@91061|Bacilli,3F52I@33958|Lactobacillaceae 91061|Bacilli S glycosyl transferase family 2 epsV - - - - - - - - - - - Glycos_transf_2 AGEJAFOK_02069 748671.LCRIS_00108 9.18e-187 523.0 COG4086@1|root,COG4086@2|Bacteria,1UY79@1239|Firmicutes,4HAZ5@91061|Bacilli,3F416@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1002) - - - - - - - - - - - - DUF1002 AGEJAFOK_02070 748671.LCRIS_00107 1.46e-189 525.0 COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V4A0@1239|Firmicutes,4HHJ9@91061|Bacilli,3F3RG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Cauli_VI,RNase_H AGEJAFOK_02071 748671.LCRIS_00106 1.51e-233 641.0 COG4814@1|root,COG4814@2|Bacteria,1UY1T@1239|Firmicutes,4I2Y3@91061|Bacilli,3F5D8@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 AGEJAFOK_02072 748671.LCRIS_00105 0.0 975.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N AGEJAFOK_02073 748671.LCRIS_00104 2.29e-112 322.0 2CCJZ@1|root,303JM@2|Bacteria,1U58T@1239|Firmicutes,4IF00@91061|Bacilli,3F565@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02074 748671.LCRIS_02005 1.28e-292 801.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease AGEJAFOK_02075 748671.LCRIS_02004 8.73e-187 518.0 COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,3F6C0@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 AGEJAFOK_02076 748671.LCRIS_02003 9.01e-287 784.0 COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae 91061|Bacilli S cog cog1373 - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 AGEJAFOK_02077 748671.LCRIS_02002 1.92e-80 239.0 COG2207@1|root,COG2207@2|Bacteria,1UI1Z@1239|Firmicutes,4HC2Y@91061|Bacilli,3F4Q1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator yneE - - - - - - - - - - - Arabinose_bd,HTH_18 AGEJAFOK_02078 748671.LCRIS_02001 2.18e-122 350.0 COG2207@1|root,COG2207@2|Bacteria,1UI1Z@1239|Firmicutes,4HC2Y@91061|Bacilli,3F4Q1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator yneE - - - - - - - - - - - Arabinose_bd,HTH_18 AGEJAFOK_02079 545697.HMPREF0216_02021 3.58e-61 196.0 COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,36H9X@31979|Clostridiaceae 186801|Clostridia S Enoyl-(Acyl carrier protein) reductase - - - ko:K07124 - - - - ko00000 - - - adh_short AGEJAFOK_02080 911104.AEKT01000057_gene146 5.05e-11 62.0 2EHZR@1|root,33BR8@2|Bacteria,1VQDB@1239|Firmicutes,4HRJT@91061|Bacilli,4AYTG@81850|Leuconostocaceae 91061|Bacilli - - - - - - - - - - - - - - PemK_toxin AGEJAFOK_02081 748671.LCRIS_01998 3.69e-54 169.0 COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,4HR7A@91061|Bacilli,3F72D@33958|Lactobacillaceae 91061|Bacilli L Addiction module antitoxin, RelB DinJ family - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB AGEJAFOK_02083 748671.LCRIS_00243 7.68e-129 366.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,3F4DZ@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair - - - - - - - - - - - - HTH_38,rve AGEJAFOK_02085 748671.LCRIS_00251 4e-79 237.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F431@33958|Lactobacillaceae 91061|Bacilli L Putative transposase DNA-binding domain - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon AGEJAFOK_02086 97137.C821_01516 4.52e-178 506.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase AGEJAFOK_02087 1423758.BN55_02645 1.34e-22 93.6 28XJS@1|root,2ZJGW@2|Bacteria,1W4NV@1239|Firmicutes,4I15N@91061|Bacilli,3F6XN@33958|Lactobacillaceae 91061|Bacilli S CRISPR-associated protein (Cas_Csn2) - - - - - - - - - - - - Cas_Csn2 AGEJAFOK_02088 748671.LCRIS_01206 6.94e-199 551.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,3F3WK@33958|Lactobacillaceae 91061|Bacilli F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase AGEJAFOK_02089 1033837.WANG_0480 4.83e-30 106.0 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,3F81Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 AGEJAFOK_02090 748671.LCRIS_01204 1.08e-92 271.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,3F6I0@33958|Lactobacillaceae 91061|Bacilli S YqeY-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY AGEJAFOK_02091 748671.LCRIS_01203 1.74e-224 619.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,3F4E7@33958|Lactobacillaceae 91061|Bacilli T phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH AGEJAFOK_02092 748671.LCRIS_01202 3.58e-129 366.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,3F516@33958|Lactobacillaceae 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 AGEJAFOK_02093 748671.LCRIS_01201 1.37e-216 597.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,3F3WQ@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 AGEJAFOK_02094 748671.LCRIS_01200 4.11e-173 483.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,3F56P@33958|Lactobacillaceae 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N AGEJAFOK_02095 748671.LCRIS_01199 9.03e-229 629.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,3F3T8@33958|Lactobacillaceae 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e AGEJAFOK_02096 748671.LCRIS_01198 0.0 1354.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,3F4G8@33958|Lactobacillaceae 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f AGEJAFOK_02097 748671.LCRIS_01197 0.0 1180.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,3F3N1@33958|Lactobacillaceae 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 AGEJAFOK_02098 748671.LCRIS_01196 9e-255 700.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,3F4CF@33958|Lactobacillaceae 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 AGEJAFOK_02099 748671.LCRIS_01195 4.34e-166 463.0 2DVJ8@1|root,33W59@2|Bacteria,1UI90@1239|Firmicutes,4HD3X@91061|Bacilli,3F3K4@33958|Lactobacillaceae 91061|Bacilli S Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 AGEJAFOK_02100 748671.LCRIS_01194 5.37e-106 305.0 COG1051@1|root,COG1051@2|Bacteria,1V6PF@1239|Firmicutes,4HKTF@91061|Bacilli,3F66W@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX AGEJAFOK_02101 748671.LCRIS_01193 2.8e-159 446.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,3F4GT@33958|Lactobacillaceae 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK AGEJAFOK_02102 748671.LCRIS_01192 8.12e-196 542.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,3F3ZD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 AGEJAFOK_02103 748671.LCRIS_01191 2.86e-307 836.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,3F45V@33958|Lactobacillaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 AGEJAFOK_02104 748671.LCRIS_01190 1.25e-80 239.0 COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,4HPK4@91061|Bacilli,3F6GC@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, GntR family lexA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR AGEJAFOK_02105 748671.LCRIS_01189 1.33e-161 453.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HG6U@91061|Bacilli,3F4GA@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AGEJAFOK_02106 748671.LCRIS_01188 1.65e-180 504.0 29NT4@1|root,309R6@2|Bacteria,1U5IX@1239|Firmicutes,4HZ1H@91061|Bacilli,3F624@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02107 748671.LCRIS_01187 2.54e-176 493.0 29NT4@1|root,30GID@2|Bacteria,1UG47@1239|Firmicutes,4IF33@91061|Bacilli,3F5H9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02108 748671.LCRIS_01186 3.85e-193 536.0 2DKIE@1|root,309JQ@2|Bacteria,1U58N@1239|Firmicutes,4IEZY@91061|Bacilli,3F55M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02109 748671.LCRIS_01185 3.49e-36 122.0 29PI4@1|root,30AG9@2|Bacteria,1U6MC@1239|Firmicutes,4IGE7@91061|Bacilli,3F858@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02110 748671.LCRIS_01184 1.27e-133 378.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HIQ4@91061|Bacilli,3F4SM@33958|Lactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 AGEJAFOK_02111 748671.LCRIS_01183 4.01e-184 511.0 2E39Q@1|root,32Y99@2|Bacteria,1VQQ8@1239|Firmicutes,4HRY1@91061|Bacilli,3F4UX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02112 748671.LCRIS_01182 4.4e-215 594.0 2EPHD@1|root,33H40@2|Bacteria,1VNCY@1239|Firmicutes,4HYY7@91061|Bacilli,3F495@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - MacB_PCD AGEJAFOK_02113 748671.LCRIS_01181 0.0 914.0 COG0144@1|root,COG0144@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli,3F492@33958|Lactobacillaceae 91061|Bacilli J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI AGEJAFOK_02114 1423767.BALU01000003_gene1156 1.28e-150 427.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3F3ZW@33958|Lactobacillaceae 91061|Bacilli G Sucrose-6F-phosphate phosphohydrolase - - 3.1.3.102,3.1.3.104,3.1.3.23 ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R00804,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 AGEJAFOK_02115 748671.LCRIS_01178 4.87e-236 650.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,3F3UY@33958|Lactobacillaceae 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh AGEJAFOK_02116 748671.LCRIS_01177 6.67e-261 714.0 COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HC93@91061|Bacilli,3F3RZ@33958|Lactobacillaceae 91061|Bacilli I phosphomevalonate kinase mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N AGEJAFOK_02117 748671.LCRIS_01176 5.87e-228 628.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli,3F4B5@33958|Lactobacillaceae 91061|Bacilli I diphosphomevalonate decarboxylase mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N AGEJAFOK_02118 405566.lhv_1275 3.02e-173 488.0 COG1577@1|root,COG1577@2|Bacteria,1UFCB@1239|Firmicutes,4HG49@91061|Bacilli,3FBNI@33958|Lactobacillaceae 91061|Bacilli I GHMP kinases N terminal domain mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N AGEJAFOK_02119 748671.LCRIS_01173 0.0 2251.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HK67@91061|Bacilli,3FCA9@33958|Lactobacillaceae 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity rexB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 AGEJAFOK_02120 748671.LCRIS_01172 0.0 2330.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,3F3Z0@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C AGEJAFOK_02121 748671.LCRIS_01171 0.0 1821.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,3F4KA@33958|Lactobacillaceae 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII AGEJAFOK_02122 748671.LCRIS_01170 1.66e-116 333.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,3F4MM@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria ypmB - - - - - - - - - - - PepSY AGEJAFOK_02123 748671.LCRIS_01169 0.0 898.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,3F4EK@33958|Lactobacillaceae 91061|Bacilli J Asparaginyl-tRNA synthetase asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon AGEJAFOK_02124 748671.LCRIS_01168 6.91e-149 419.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,3F4FF@33958|Lactobacillaceae 91061|Bacilli L DnaD domain protein dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 AGEJAFOK_02125 748671.LCRIS_01167 1.92e-148 417.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,3F42U@33958|Lactobacillaceae 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD AGEJAFOK_02126 748671.LCRIS_01166 0.0 1360.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F424@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein 1A ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 AGEJAFOK_02127 748671.LCRIS_01165 8.47e-152 426.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,3F4DG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU AGEJAFOK_02128 748671.LCRIS_01164 1.18e-139 394.0 COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,3F4MR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 AGEJAFOK_02129 748671.LCRIS_01163 1.85e-90 265.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,3F6VZ@33958|Lactobacillaceae 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA AGEJAFOK_02130 748671.LCRIS_01162 1.68e-277 758.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,3F3NZ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 AGEJAFOK_02131 748671.LCRIS_01161 6.74e-309 840.0 COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,4HG8Z@91061|Bacilli,3F483@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase cpdA - - - - - - - - - - - Metallophos AGEJAFOK_02132 748671.LCRIS_01160 9.67e-104 299.0 28WWC@1|root,2ZIVN@2|Bacteria,1W4GP@1239|Firmicutes,4I0DB@91061|Bacilli,3F5SC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02133 748671.LCRIS_01159 9.91e-150 421.0 COG0127@1|root,COG0127@2|Bacteria,1U7FQ@1239|Firmicutes,4IHBR@91061|Bacilli,3F9JR@33958|Lactobacillaceae 91061|Bacilli F Ham1 family - - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like AGEJAFOK_02134 748671.LCRIS_01862 0.0 945.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD4 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 AGEJAFOK_02135 1033837.WANG_1375 2.12e-132 378.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,3F4RP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AGEJAFOK_02136 748671.LCRIS_01868 1.05e-233 645.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,3F3K5@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease yxeA - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD AGEJAFOK_02137 748671.LCRIS_01869 1.45e-119 342.0 COG1309@1|root,COG1309@2|Bacteria,1V4D3@1239|Firmicutes,4HJ8Z@91061|Bacilli,3F6ZM@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N AGEJAFOK_02138 748671.LCRIS_01870 2.75e-143 404.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F5SD@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase - - - - - - - - - - - - His_Phos_1 AGEJAFOK_02139 748671.LCRIS_01871 9.79e-181 503.0 COG1073@1|root,COG1073@2|Bacteria,1V43W@1239|Firmicutes,4HNBU@91061|Bacilli,3F4SI@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 AGEJAFOK_02140 748671.LCRIS_01872 1.45e-183 510.0 COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,4HFN2@91061|Bacilli,3F4KR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0246 family XK27_08125 - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD AGEJAFOK_02141 748671.LCRIS_00990 4.66e-277 758.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,3F3XX@33958|Lactobacillaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein AGEJAFOK_02142 748671.LCRIS_00991 1.19e-43 148.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,3FB4S@33958|Lactobacillaceae 91061|Bacilli S reductase - - - - - - - - - - - - Aldo_ket_red AGEJAFOK_02143 748671.LCRIS_00991 2.98e-50 166.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,3FB4S@33958|Lactobacillaceae 91061|Bacilli S reductase - - - - - - - - - - - - Aldo_ket_red AGEJAFOK_02144 748671.LCRIS_00991 1.26e-40 140.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,3FB4S@33958|Lactobacillaceae 91061|Bacilli S reductase - - - - - - - - - - - - Aldo_ket_red AGEJAFOK_02145 748671.LCRIS_00992 1.83e-190 529.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase yxeH - - - - - - - - - - - Hydrolase_3 AGEJAFOK_02146 748671.LCRIS_00993 1.14e-230 635.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HUAD@91061|Bacilli,3FB6D@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gyaR - 1.1.1.26,1.1.1.399,1.1.1.95 ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020 R00717,R01388,R01513 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C AGEJAFOK_02147 748671.LCRIS_00994 0.0 874.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid yhdG - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 AGEJAFOK_02148 748671.LCRIS_01793 1.5e-27 102.0 29PFZ@1|root,30AE4@2|Bacteria,1U6IT@1239|Firmicutes,4IGB6@91061|Bacilli,3F800@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun AGEJAFOK_02150 97137.C821_01523 1.23e-54 180.0 COG1566@1|root,COG1566@2|Bacteria,1UI96@1239|Firmicutes,4ISGN@91061|Bacilli,3FBT7@33958|Lactobacillaceae 91061|Bacilli V HlyD family secretion protein - - - ko:K20345 ko02024,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112,8.A.1 - - HlyD_3 AGEJAFOK_02151 272621.LBA1796 0.0 1110.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,3F3QF@33958|Lactobacillaceae 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 AGEJAFOK_02152 748671.LCRIS_01615 1.64e-101 303.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F6AD@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg AGEJAFOK_02153 1033837.WANG_0201 1.79e-99 298.0 COG3290@1|root,COG3290@2|Bacteria,1V1ET@1239|Firmicutes,4HGNA@91061|Bacilli,3F71I@33958|Lactobacillaceae 91061|Bacilli T GHKL domain - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 AGEJAFOK_02154 748671.LCRIS_00428 3.09e-71 215.0 29P3Z@1|root,30A26@2|Bacteria,1U63A@1239|Firmicutes,4IFSN@91061|Bacilli,3F6XS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02155 1423767.BALU01000013_gene122 2.96e-23 95.5 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,3F6KB@33958|Lactobacillaceae 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 AGEJAFOK_02156 748671.LCRIS_00426 4.28e-187 521.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,3F49U@33958|Lactobacillaceae 91061|Bacilli M mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel AGEJAFOK_02157 1545701.LACWKB10_0648 4.52e-126 367.0 COG1131@1|root,COG1131@2|Bacteria,1TQA2@1239|Firmicutes,4HEU0@91061|Bacilli,3FC3N@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AGEJAFOK_02158 1423748.BALB01000005_gene732 4.31e-175 501.0 28MM7@1|root,2ZAX4@2|Bacteria,1TT1Z@1239|Firmicutes,4HDYX@91061|Bacilli,3F45B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - ABC2_membrane_2 AGEJAFOK_02159 1545701.LACWKB10_0646 5.53e-147 427.0 28MJI@1|root,2ZAW0@2|Bacteria,1UZZX@1239|Firmicutes,4HCUA@91061|Bacilli,3F5KU@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - AGEJAFOK_02163 748671.LCRIS_01741 0.0 1142.0 COG1621@1|root,COG1621@2|Bacteria,1TR8C@1239|Firmicutes,4HBYU@91061|Bacilli,3F5DC@33958|Lactobacillaceae 91061|Bacilli M Levansucrase/Invertase sacB GO:0005575,GO:0005576 2.4.1.10,2.4.1.9 ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R04194,R05140 RC00077,RC00247 ko00000,ko00001,ko01000,ko01003 - GH68 - Glyco_hydro_68,Gram_pos_anchor,SH3_8 AGEJAFOK_02164 1293597.BN147_07160 2.36e-12 73.2 2D8CX@1|root,32TR0@2|Bacteria,1VAF6@1239|Firmicutes,4HP2N@91061|Bacilli,3F636@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage abortive infection AbiH - - - - - - - - - - - - AbiH AGEJAFOK_02165 1114972.AUAW01000026_gene771 3.43e-79 250.0 COG1018@1|root,COG1018@2|Bacteria,1U7BA@1239|Firmicutes,4IH6A@91061|Bacilli,3F99Q@33958|Lactobacillaceae 91061|Bacilli C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - FAD_binding_6,Fer2,NAD_binding_1 AGEJAFOK_02166 1114972.AUAW01000026_gene770 1.24e-188 544.0 COG1233@1|root,COG1233@2|Bacteria,1UU71@1239|Firmicutes,4HA25@91061|Bacilli,3F9H5@33958|Lactobacillaceae 91061|Bacilli Q HI0933-like protein - - 5.2.1.13 ko:K09835 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R07512 RC01960 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase AGEJAFOK_02167 1114972.AUAW01000026_gene769 7.13e-67 213.0 COG2186@1|root,COG2186@2|Bacteria,1V1Y0@1239|Firmicutes,4IGIN@91061|Bacilli,3F8CS@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - FadR_C,GntR AGEJAFOK_02168 1423790.BN53_09240 5.71e-230 641.0 COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,4HF0C@91061|Bacilli,3F5RT@33958|Lactobacillaceae 91061|Bacilli K Putative ATP-dependent DNA helicase recG C-terminal - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4 AGEJAFOK_02169 944562.HMPREF9102_0712 8.04e-143 410.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F42F@33958|Lactobacillaceae 91061|Bacilli E alcohol dehydrogenase adh2 - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N AGEJAFOK_02170 748671.LCRIS_00570 2.33e-230 635.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,3F55I@33958|Lactobacillaceae 91061|Bacilli E M42 glutamyl aminopeptidase pepA - - - - - - - - - - - Peptidase_M42 AGEJAFOK_02171 748671.LCRIS_00571 0.0 1067.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,3F3ZJ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn AGEJAFOK_02172 748671.LCRIS_00572 6.07e-223 614.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,3F4U1@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red AGEJAFOK_02173 748671.LCRIS_00573 1.53e-176 493.0 29NJ9@1|root,309H6@2|Bacteria,1U538@1239|Firmicutes,4IEUK@91061|Bacilli,3F4AG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02174 748671.LCRIS_00574 1.11e-256 707.0 COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,4HBGT@91061|Bacilli,3F3YJ@33958|Lactobacillaceae 91061|Bacilli E amino acid steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 AGEJAFOK_02175 748671.LCRIS_00574 3.97e-33 125.0 COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,4HBGT@91061|Bacilli,3F3YJ@33958|Lactobacillaceae 91061|Bacilli E amino acid steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 AGEJAFOK_02176 748671.LCRIS_00575 3.41e-312 851.0 COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,4HBGT@91061|Bacilli,3F3YJ@33958|Lactobacillaceae 91061|Bacilli E amino acid steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 AGEJAFOK_02177 748671.LCRIS_00576 1.07e-165 462.0 COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,4HHTX@91061|Bacilli,3F4AV@33958|Lactobacillaceae 91061|Bacilli F glutamine amidotransferase - - - - - - - - - - - - GATase AGEJAFOK_02178 748671.LCRIS_00577 2.05e-188 524.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HBM1@91061|Bacilli,3FC55@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter peb1A - - ko:K10039 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 AGEJAFOK_02179 748671.LCRIS_00578 2.53e-106 306.0 COG1846@1|root,COG1846@2|Bacteria,1VF1A@1239|Firmicutes,4HH6N@91061|Bacilli,3F705@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, MarR family - - - - - - - - - - - - HTH_27,MarR_2 AGEJAFOK_02180 748671.LCRIS_00579 0.0 1079.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein XK27_09600 - - ko:K06147,ko:K18891 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 - - ABC_membrane,ABC_tran AGEJAFOK_02181 748671.LCRIS_00580 0.0 1109.0 COG1132@1|root,COG1132@2|Bacteria,1UNRI@1239|Firmicutes,4HFD4@91061|Bacilli,3FC4R@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region XK27_09605 - - ko:K18892 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.135 - - ABC_membrane,ABC_tran AGEJAFOK_02182 748671.LCRIS_00581 1.72e-129 368.0 COG4721@1|root,COG4721@2|Bacteria,1V39N@1239|Firmicutes,4HF32@91061|Bacilli,3F4QM@33958|Lactobacillaceae 91061|Bacilli S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt AGEJAFOK_02183 748671.LCRIS_00582 8.41e-314 857.0 COG2211@1|root,COG2211@2|Bacteria,1UI2Y@1239|Firmicutes,4ITMN@91061|Bacilli,3FBX0@33958|Lactobacillaceae 91061|Bacilli G MFS/sugar transport protein - - - - - - - - - - - - MFS_1 AGEJAFOK_02184 1423748.BALB01000004_gene547 5.43e-50 163.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4IQTA@91061|Bacilli,3FCEB@33958|Lactobacillaceae 91061|Bacilli F Zeta toxin udk - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK AGEJAFOK_02185 748671.LCRIS_00583 2.72e-60 190.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4IQTA@91061|Bacilli,3FCEB@33958|Lactobacillaceae 91061|Bacilli F Zeta toxin udk - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK AGEJAFOK_02186 748671.LCRIS_00584 2.8e-173 483.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran AGEJAFOK_02187 748671.LCRIS_00585 3.39e-187 521.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli,3F4GG@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein glnH - - ko:K10039 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 AGEJAFOK_02188 748671.LCRIS_00586 4.29e-122 351.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HFBH@91061|Bacilli,3F3XW@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnM GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 AGEJAFOK_02189 748671.LCRIS_00587 3.65e-141 400.0 COG0765@1|root,COG0765@2|Bacteria,1UJM4@1239|Firmicutes,4HBAS@91061|Bacilli,3F3WJ@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 AGEJAFOK_02190 748671.LCRIS_00588 1.04e-211 585.0 2CJHH@1|root,32SA1@2|Bacteria,1V6G9@1239|Firmicutes,4HIZ6@91061|Bacilli,3F5FF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 AGEJAFOK_02191 748671.LCRIS_00591 2.09e-110 318.0 29NRA@1|root,309X2@2|Bacteria,1U5VE@1239|Firmicutes,4IFJ4@91061|Bacilli,3F6JW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02192 748671.LCRIS_00592 3.52e-296 813.0 2EM25@1|root,33ERN@2|Bacteria,1VK4A@1239|Firmicutes,4HRGD@91061|Bacilli 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2325) - - - - - - - - - - - - DUF2325 AGEJAFOK_02193 748671.LCRIS_00593 2.2e-308 841.0 COG1653@1|root,COG1653@2|Bacteria,1UNFN@1239|Firmicutes,4HCSA@91061|Bacilli,3FBF0@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein srrA1 - - ko:K02027,ko:K17244 ko02010,map02010 M00207,M00601 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.40 - - SBP_bac_1,SBP_bac_8 AGEJAFOK_02194 748671.LCRIS_00594 7.29e-209 575.0 COG1085@1|root,COG1085@2|Bacteria,1TSNU@1239|Firmicutes,4H9TY@91061|Bacilli,3F3JH@33958|Lactobacillaceae 91061|Bacilli C Domain of unknown function (DUF4931) - - - - - - - - - - - - DUF4931 AGEJAFOK_02195 748671.LCRIS_00595 8.52e-215 593.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,3F3S5@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB,Rib_5-P_isom_A AGEJAFOK_02196 748671.LCRIS_00596 2.59e-161 452.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,3F43N@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A AGEJAFOK_02197 748671.LCRIS_00597 0.0 1288.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans AGEJAFOK_02198 748671.LCRIS_00598 1.01e-222 613.0 COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,4HB17@91061|Bacilli,3F4T0@33958|Lactobacillaceae 91061|Bacilli F Nucleoside rihC - 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro AGEJAFOK_02199 748671.LCRIS_00599 6.63e-174 484.0 COG2188@1|root,COG2188@2|Bacteria,1TTCD@1239|Firmicutes,4HEXQ@91061|Bacilli,3F4DA@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein gntR - - - - - - - - - - - GntR,UTRA AGEJAFOK_02200 748671.LCRIS_00600 3.18e-198 549.0 COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,4HWAW@91061|Bacilli,3F3Z7@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 AGEJAFOK_02201 748671.LCRIS_00601 2.9e-79 235.0 29P3Y@1|root,30A25@2|Bacteria,1U639@1239|Firmicutes,4IFSM@91061|Bacilli,3F6XR@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun AGEJAFOK_02202 748671.LCRIS_00602 4.44e-174 486.0 COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HG12@91061|Bacilli,3F3UT@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR AGEJAFOK_02203 748671.LCRIS_00603 0.0 1652.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N AGEJAFOK_02204 748671.LCRIS_00604 1.85e-205 568.0 COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,4HCHJ@91061|Bacilli,3F52H@33958|Lactobacillaceae 91061|Bacilli S Phospholipase, patatin family - - - - - - - - - - - - Patatin AGEJAFOK_02205 748671.LCRIS_00605 7.44e-189 525.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 AGEJAFOK_02206 748671.LCRIS_00606 0.0 1238.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,3F44V@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system, EIIB glvC - 2.7.1.208 ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 M00268 R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8 - - PTS_EIIB,PTS_EIIC AGEJAFOK_02207 748671.LCRIS_00607 6.89e-190 527.0 COG1737@1|root,COG1737@2|Bacteria,1V2J8@1239|Firmicutes,4IQVX@91061|Bacilli,3FBJH@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family glvR - - ko:K03481 - - - - ko00000,ko03000 - - - HTH_6,SIS AGEJAFOK_02208 748671.LCRIS_00608 1.52e-103 300.0 2CJCY@1|root,309TS@2|Bacteria,1U5P7@1239|Firmicutes,4IFDR@91061|Bacilli,3F69B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02209 748671.LCRIS_00609 1.96e-113 325.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,3FC0X@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ptbA - 2.7.1.208 ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 AGEJAFOK_02210 748671.LCRIS_00610 1.76e-52 165.0 29PEW@1|root,30AD2@2|Bacteria,1U6H9@1239|Firmicutes,4IG9K@91061|Bacilli,3F7X8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AGEJAFOK_02211 748671.LCRIS_00611 2.14e-154 433.0 COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,4HN5N@91061|Bacilli,3F6YM@33958|Lactobacillaceae 91061|Bacilli C nitroreductase - - - - - - - - - - - - Nitroreductase AGEJAFOK_02212 748671.LCRIS_00612 0.0 868.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3TX@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 AGEJAFOK_02213 748671.LCRIS_00613 8.59e-133 376.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,3F56C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran AGEJAFOK_02214 748671.LCRIS_00614 0.0 1132.0 COG1053@1|root,COG1053@2|Bacteria,1TTD3@1239|Firmicutes,4HT4K@91061|Bacilli,3F5DN@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind,FMN_red AGEJAFOK_02215 1423748.BALB01000009_gene1024 2.88e-113 326.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 AGEJAFOK_02216 748671.LCRIS_00617 5.83e-67 203.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 AGEJAFOK_02217 748671.LCRIS_00618 1.93e-268 746.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,3F53U@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind,FMN_red,Shikimate_dh_N AGEJAFOK_02218 748671.LCRIS_00618 7.32e-157 455.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,3F53U@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind,FMN_red,Shikimate_dh_N ## 1976 queries scanned ## Total time (seconds): 1.6755108833312988 ## Rate: 1179.34 q/s