LOCUS       c00098_gnlPro..        12353 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IILAAPPH_128.
ACCESSION   c00098_gnlPro..
VERSION     c00098_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 17:04:46
            Original ID  :: gnl|Prokka|IILAAPPH_128
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12353
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12353
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3896:6431]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3897..6431
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..12353
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12353
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             191..505
                     /locus_tag="ctg98_1"
                     /transl_table=11
                     /translation="MKRCKNWVVTIVAFLMLVGEISVLPANLQGSTSVVNAAIHHRRRK
                     HQYRDKTKIYTSNYRIVDNKRSKIFHVMRGHNYRMNRENAVFFKSKAAARAAGYRESKR
                     "
     CDS             complement(546..2846)
                     /locus_tag="ctg98_2"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGKVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNRYIITINFIN"
     CDS             2975..3823
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg98_3"
                     /sec_met_domain="LysR_substrate (E-value: 1.7e-29,
                     bitscore: 92.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQPKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             3897..5126
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_4"
                     /sec_met_domain="Amidinotransf (E-value: 2.4e-109,
                     bitscore: 355.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELLTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             5137..5568
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_5"
                     /sec_met_domain="OTCace_N (E-value: 5.2e-38, bitscore:
                     120.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             5529..6431
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_6"
                     /sec_met_domain="OTCace (E-value: 5.2e-47, bitscore: 149.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 2.5e-20, bitscore:
                     63.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQNFA
                     QDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTP
                     DDQLIFMHCLTAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIK
                     AVMAATLGNLFIPIACGGGGILVIVKDGHLRGVAGVIHKDFSAAKMAEDINADELVILT
                     TVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGSMKPKIEAAIEFVEKTGNLAII
                     TSLSNANKLADGVGTIIYN"
     CDS             6445..6981
                     /locus_tag="ctg98_7"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDINMNI
                     PGPIKNNRYLTKMFMLGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFENQISLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             7061..7858
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg98_8"
                     /sec_met_domain="Acetyltransf_10 (E-value: 2.8e-08,
                     bitscore: 23.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKFIDVRIGISMELKKNKNNLKQITALIQYAFLKNNDLTKDENF
                     MSRYDHSTGYGYFDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQL
                     MKEILHDLHRQDIPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIV
                     RGKWDNLAVQNGVIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERP
                     ISYLIYRIRDNTFLADEMYAITPQGLLSMFGFMGSRAVLSNLK"
     CDS             7855..8259
                     /locus_tag="ctg98_9"
                     /transl_table=11
                     /translation="MSVPEKSLRAELFPEQNELQVDLRPYMMSRIIDFEKVLACMRPMQ
                     EGDFNLEVNSDEQCPWNIGVWQLSNHGRKVAVERKEDALVDFSGSITAWTQVLLGRLTM
                     NAAVKLGLITDYRIKKLDFVKGDVSFYDYF"
     CDS             8275..8436
                     /locus_tag="ctg98_10"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             8438..9043
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg98_11"
                     /sec_met_domain="LysR_substrate (E-value: 1.6e-12,
                     bitscore: 37.3, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHDGAFA
                     KLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDMTCFI
                     VAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASRSGYFILNENTARLINTTDL
                     QPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             9099..9209
                     /locus_tag="ctg98_12"
                     /transl_table=11
                     /translation="MKADSYILHSGDDFYAKKNFVTFNINGTCFRINWFG"
     CDS             9175..9681
                     /locus_tag="ctg98_13"
                     /transl_table=11
                     /translation="MVLVLGLTGLASQVETVDASTYGNGVQVTIPKKMQGTWYSYDRNA
                     HNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWMSGKTTKMKNDT
                     FYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKLAKKMKDYKFKK
                     VNYTL"
     CDS             9747..10439
                     /locus_tag="ctg98_14"
                     /transl_table=11
                     /translation="MTKLILGGEVMKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTS
                     QENEPGTLFMQTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVE
                     LFPEFISTKAEKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAM
                     IAGTVADQPNEWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVD
                     QGAIFYQP"
     CDS             complement(10537..10665)
                     /locus_tag="ctg98_15"
                     /transl_table=11
                     /translation="MKGMRTLIKLLLIGGSFLTLGLMAISSVLINKPAVAKVKHRH"
     CDS             11009..12049
                     /locus_tag="ctg98_16"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKRPA
                     SKSKRVKTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDNRNNY
                     EFDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLI
                     DVLRKM"
ORIGIN
        1 gctttggtca ggttcaggac accttagaat cctactttga ttaaataaat aattaaaaaa
       61 tcaatttacg agaaagaact atttacacaa aagatttgac agtttcaaac tagtttctaa
      121 taaacgtagg aacacttcat atataaacgt atactatata aatatagtga catattaagg
      181 gagtgttttt atgaaaagat gcaagaattg ggttgtgact attgttgcat ttctgatgtt
      241 agtgggagaa atcagtgttc tgcctgcaaa tttgcagggg tcgacatcag ttgttaatgc
      301 agctattcat cacagaagga gaaagcatca atatcgtgat aaaactaaga tttataccag
      361 taattacaga attgttgata ataaacgatc aaaaatcttt cacgtaatgc gcggtcataa
      421 ttatcgaatg aatcgtgaaa atgcagtttt cttcaagagt aaagcagcag cacgtgcagc
      481 aggatatcgt gaatcaaaaa gataaattaa aagacttcta agagttcaaa gttcctagaa
      541 gtcttttaat ttataaaatt tatggtaata atatacctgt ttttcatcac aggttggtaa
      601 attaagtcga ttattatggc agcaataatc gctacaatta cagtaattgc taagttttga
      661 atggaaatct ggaccattgc ccaaccacaa agagctaaga taaaggtcaa tagaacatct
      721 gcaatttgaa cactaccaac caacttggat gggtaatctt gccaaaagta cttacgagtt
      781 ctagtaatca aaacaatcaa cattgcgcta agaactaggt atacgtaaac catagtagaa
      841 acagcaccgt gactccaacc gtgtgtgttt aagaaccaaa caaacccaat accaattaaa
      901 gtccaaccag cagctagtga aaaggcgatc ttagcaagct tagccatatt ccagttttct
      961 ggcttataag taatgtgagt cctgtcagtt ccaatcatca tcgtaaccat attgttcata
     1021 atggtataga taaccattgc attcaaggcc attgggatgt agtcaaagaa aagatagcca
     1081 aaagttaaca gcatcgttaa ttcagcagtt ctagcaagct tggttagtga ccaagtagtc
     1141 attctttggt atacgcgatg tccagcgtct aaaattttaa caattgagcc tagaccatcg
     1201 tctagtaata ccattttacc cgaacgctta gctacgtcag cagcatttga aactgcgatt
     1261 cctacttcag cttgttttaa tgcaggcgcg tcgttaactc cgtcacctgt catccctacg
     1321 atatagcctt tttcttggaa aagctttacc atcttgagtt tatcttctgg taaaacatca
     1381 gcaataccgg ccaaatcatt aatatcagta ttttcattga aatcgtgaat cgaaattact
     1441 ttaccagtta aatcaacttg ttctgccact gcagcagcgg tcttttgatt gtcaccagtt
     1501 aacataattg ggcgaacgcc acgtttcttg agttcagcca aagctgcttt agagtctgtt
     1561 ctaactttat cttgtaagat gaagacacca gctaacttat cgtcaatcaa gactgccact
     1621 gagcgtcctg ccttgaaatt aattccagaa atttcttcat cggcatgttt atcgatcaaa
     1681 gataattgct taaatgaacc aagctttaca ttatgtccag caacatcagc catagaataa
     1741 ccagtgtcag aagtaaatgg agtaaagttt tcagcattca tgactggaat gttattttct
     1801 actaagtatt catcgattgc tgtatcgata ataccagcat tacgtttatc agttgcggct
     1861 ccagctaaag caagcacgtc tttgtcaggc aagtcactta gatcagtcca agcggctacg
     1921 gcagttttgt tttccgtaat tgttccagtc ttatcaagta aaagcaagtt caagttagct
     1981 gcgtcctgaa ttccagttag gtcagaagtc aggactcctt ctttacttaa gcgggttgct
     2041 tcaaatgagt tggataaagc aaaagttgat ggcattgcta caggaattga agcaataaac
     2101 atcattgcca ggaatggcaa catattaata aaggtattga aattaccgcc tttgaagaag
     2161 gaggcgataa taataactaa ggttaaaaca ccatctagta agcaaaggta gtagataatc
     2221 ttagtcaaaa gttgttgtaa gtgaccagga gcagcggaat tgttgatcaa attaatcgtc
     2281 ttaccgcttc tagaatcttt acctgtagca gtaacaacag ctaggccatc accttcaaca
     2341 actgtagtac cggcaaaggc ggtgtcatca attgctttct taactggttt agattcacct
     2401 gtaattgagc tttcatcaca agctaagtta ccgtcaacaa ttttaacatc tgctgcgagt
     2461 acgtccccgc gtttaagtga gattaaatcg cctttaacta gttgtttaga atcaagtttg
     2521 atccacttgc catcgcgttc aactgataca gtaggagtca acttgtgtga aatattattt
     2581 aaaactcgtc ttgattgctt tttcttagat gcaccgttaa atgcagcaaa taaaagcatc
     2641 aacaacacga ataatgattg gacccatttg cccaagatac attctagaat taaagcagct
     2701 tctagaatcc aagcggatag gttccataac ttagacaaga actctttaaa gaaattgtat
     2761 tcaggctctg gtacttcatt taagccatct tcttttaagc gcttgtctgc ttcggcttga
     2821 gttaagccgt gaaatttatc agacattatt ttccctccaa atctacctta ataaggtagc
     2881 acagatattg ctatgaataa aatactaaaa tacaatataa gatattaaat attttaatat
     2941 cactatcaat tgaaataaaa aaaggataaa taatatgaat ctaaaacagt tacgttattt
     3001 tctagttgta gcagaagaaa agcagattac agcagctgct aagcgcttgt atattgcaca
     3061 gccaccatta agctatcaat taaaacaatt agagaaagag ttgggcgcgc aattatttaa
     3121 aagaacggca catggtattg agctaactga tgtgggacaa atttttcaaa gctatgccaa
     3181 tgaaattatt tctctagctc aaaatgctga aaaccaagta cataagacta tttccggtga
     3241 attgggaacg attgcaattg gaatggcatc ttcctcaacg ggcttgatac caatgaattc
     3301 ttttaatgaa ttacgaaaat attatccgga aatttctttt gatatttatg aagataatac
     3361 ttatggcatc ctggataaat tagaaaaaaa gacaatcgat ctaggcattg tacgaacgcc
     3421 ttacaaccag acaggtttaa atactaagac tttaacaact gaaaaaatga tggctattag
     3481 tgtagaccca gattttcagc caaaaaaaga attacgcatt aaagatctag cagatcagcc
     3541 attgattatt tatcgtcgct ttgaggatat ttttaatcaa acttttgcac atcatgggct
     3601 taaaccattt tatgcggtta agtgtgatga ttcacggaca gcaattactt gggccaagag
     3661 aaaaatggga gtagcgctag taccagaatc aattgcgaca acttatgccc aagaaaatat
     3721 gatcgcaatt aaacatgcta attggataac acatttgcag ctggtttggc gtaaagatca
     3781 tcaagttaca cctttaatga aaaaaatcat tgctgcaata tgataatact gtaactttta
     3841 cctaattgat ccataataaa tgtaaacggg tacaataatt aatagaaggt ggttgaatgt
     3901 cgagtccgat tcatgtttat tcagaaattg gtaagttaaa aacggtgatg ttacatcgac
     3961 cgggaaaaga actagaaaat ctagccccag atattttgca tcgaatgttg attgacgata
     4021 ttccttatct gaagattgcc caagaagaac atgatgcttt tgcgcatgta ttgaggcagc
     4081 aggggatcaa agtattatat cttgaggatt tattagcaga atctttaaca gatgagaaag
     4141 ttcgtcgggc attcttagat cagttactgg atgaatcaag tattaaaaaa caggatcctt
     4201 tgcatcaatt attgctgaac tatctccaag aattgctaac taaggaaatg gtaaaaacgg
     4261 tgattgctgg aattagaaaa agtgcgattc ataattctac cccatcttta gcagatttgg
     4321 ctgaggaccc agattaccct ttttatcttg atccaatgcc aaatgtatat tttactcgag
     4381 atcaacaggc tgcaattggt tcagggatga ccattaaccg gatgactttc agagctagac
     4441 gacgtgaatc attatttatg gaaacaattt tgaaaaatca tcctgatttc aagaacgcaa
     4501 ctattccagt ttggcgtgac cgttatcatc atggtcgcct tgagggcggg gatgaactag
     4561 ttctaaataa ccatgtgtta gctgtaggta tttcacaacg cacttctgca actgcaatta
     4621 ctgacttagc tcataattta tttgatcatt caagttatga tacgatttta gcgattaaga
     4681 ttccgcacaa tcatgctatg atgcaccttg atacagtttt tacaatgatt aattataatc
     4741 aatttacggt tcatcccttt attttagata aagccggcaa aattgatatt tatgttctac
     4801 agcccgatga tcacaacggt gtaaaaatca cagaaaagaa tgatttggtg caggttttga
     4861 aagaaaactt acatttaagc gaattggatt taattccaac tggtggtggt gatccaattg
     4921 ccgcaccacg tgaacaatgg aatgacggct caaatacctt ggcaattgca ccaggtgaag
     4981 tcgttactta tgatcgtaat tatgtatcca atgatttgct aagaaaacat ggcatcatcg
     5041 ttcatgagat tcggtctagt gaactctcac gtggtcgtgg cggtcctaga tgtatgtcgt
     5101 gtccgttgat tcgtgaagat ttataagagg caaaaaatga aatatttaca aaatgttttt
     5161 caaggtagaa gttttctcga ttgtaaagac tatactccag ctgaaatttc atatttaatt
     5221 gattttgcat tacatttaaa agaacttaaa aaagagcata tcccacatga atatctgaaa
     5281 ggtaaaaata ttgcactact ttttgaaaaa gcctcaacta ggacgcgatc tgcttttgta
     5341 gtagcttgta atgatttagg tgctcatcca gaatatctag gcgcaagcga gatccactta
     5401 ggtaaaaaag aaagcgtcaa ggatacggct aaagtcctag gctcaatgta tgatggaatt
     5461 gaatatcgcg gttttgctca agaagatgta gaagagctgg ctaaatattc tggcgttcct
     5521 gtttggaagt gggtgatggc cgcgataatg ttgccgacag tcttttagtt tgtggctcaa
     5581 tgttaggtgt taatgtacat attgttacac ccaagccttt gtttacacat cctgatgtac
     5641 aaaaaattgc tcaaaatttt gcccaagatt caggttcaaa aaatttgatc acagatgata
     5701 ttgctcaagg cgttaaagga gccaatgttg tttataccga tgtttgggtt tcgatgggtg
     5761 aaaatgattg gtctgaacga attaaattat taaagccata tacggtcaca atgaaaatga
     5821 tgcaaatgac tggtacacca gatgaccaat tgatctttat gcattgtttg acagcttttc
     5881 atgatcgaac aactcaggtg ggagaagaaa tctatgaaaa atatggctta aatgagatgg
     5941 aagtaactga tgaggtcttt aattcaaagt atgcttggca atttacagaa gctgaaaatc
     6001 gattgcattc aattaaagca gtgatggcgg ctactttagg aaatttattt attccgattg
     6061 cctgtggcgg tggtggcatc cttgttattg tgaaagatgg gcatctcaga ggtgttgccg
     6121 gcgtaattca taaagatttt tccgctgcta aaatggcaga agatatcaac gctgatgaat
     6181 tagtaattct aacaacggtg gatcatgcat ttttgaatta tggcaaagaa aatcaacaag
     6241 caattggtaa aataaaagtt gaacagctca aacaatatct agcagcaggt tatttcgcag
     6301 ctgggagtat gaagcctaag atagaagctg caattgaatt tgtagaaaaa acaggtaatt
     6361 tagcaattat cacctctttg agcaatgcca acaaactagc agacggagtc ggcacaatca
     6421 tttataatta actgggtgat aaaaatgaat atttttaatg aaggaaaaaa gcaggatatt
     6481 gcccaagttt tagcagctaa agataggcga gtagctgtac aacataagat ttttaataag
     6541 tatcctaatc aaactctagt cgacattaat atgaatatcc caggaccaat caagaataat
     6601 cgctatttaa ctaaaatgtt tatgttgggt atcaatgagc tggaaaatgc ttggactaac
     6661 ctaggttatc attttaaatt ggtgacacag cttaatgatg atagtggctg tgaaaacttt
     6721 tatgtattat ctttgtcaat tgaaaaagta aagcgctcaa caattgattt tgagaatcag
     6781 atatcattgg gacgtctctt tgatgcagac gtgttggtaa aaaataaaca agctgcaatt
     6841 tcacgcagag atttgggcag gcagccacgt aagtgctttt tatgtgatcg ccctgctaaa
     6901 gaatgtgctc gcagccggag acattcagtg gaacagatgc aggcatttat ctctcagctt
     6961 tatcaagaat acgttgcgta aaataaaccg ggattttatg attccggttt atttttatga
     7021 aaaatctagt taaaaattta aaaaatgaac taaaatagta atgaataaat ttatagatgt
     7081 acgtatagga ataagcatgg aattaaagaa aaataagaat aatttaaagc aaattacggc
     7141 attaattcaa tatgcatttt tgaaaaataa tgatttgact aaagacgaaa attttatgag
     7201 tcgttatgat catagtacag gttatggcta ttttgataag gaaaaattag ctagctatat
     7261 tatggttaat cgatttaaaa gtgatgtttt tgggcatcat ttaccgatgg ctggaatagg
     7321 ttatgtagct tcatatcctg agtatcgtgg ccaaggtcat atttcccaat taatgaaaga
     7381 aattttgcat gacttacata ggcaagatat tccgtttgct aacctggcac cattttcgga
     7441 gagcttttat cgccagtacg ggtttagcaa tagtatttat caaaaagaat atcgctttga
     7501 tggaagcgca ttgcgtagtt ttaaattacc acgttctggt catatagtgc gtggcaagtg
     7561 ggacaattta gctgttcaaa atggtgtgat tcaactttat gaacgtcaac tgcatactga
     7621 tgatgaacgt aacacggttg tacgtgaggc atggtggtgg aatagacttg attcttatta
     7681 tcatcaccgc aatgtagccg tttattttga cgcggatgag cggccaatta gttacttgat
     7741 ttatcgcatt agagacaata cttttttagc tgatgaaatg tacgcaatta cgccgcaggg
     7801 attactgagt atgtttggtt ttatgggttc gcgggcagtg ttaagcaatt taaaatgagc
     7861 gtaccagaga aatcgttacg agctgaactt tttcctgaac aaaacgaact ccaagttgat
     7921 ttgcgtcctt atatgatgag tcgaattatt gattttgaaa aagttttggc ttgtatgcgg
     7981 ccaatgcaag aaggtgattt taatctggaa gtcaatagcg atgaacagtg tccttggaat
     8041 attggagttt ggcaattaag taatcatgga cgtaaggtag cggtagaacg taaggaagat
     8101 gcattggttg atttttcggg atcaattacc gcgtggaccc aggtgctatt aggtagacta
     8161 accatgaatg ctgctgttaa actaggatta attacagatt accgcatcaa aaaattagat
     8221 ttcgttaaag gcgatgtatc attttatgat tatttttagt tgtgaggtta aaaaatgagt
     8281 aaagaaaaga aactcaattt aataaaatta tttggcattg tagttagtgg tttgaatttg
     8341 atcttttttg ccttgatggc acttaataag catgaagata ctaaggataa aagaagagta
     8401 gcagaagaag gacacgcacc gctggatgaa aaataaaatg acggaattaa agattgcata
     8461 ttttgaccaa ttaggtcgta aggaattaga tcaggcagtg cagcattttg tgttaaaaca
     8521 tcctaatgta gatgtaaaac tacttgcgac tagtcatgat ggtgcttttg caaaactgaa
     8581 tgaagatgaa gcagacatag caatcaatga tttgcgtgac gagaatctta actttgatga
     8641 aacagaattg actcaagctg gtgtaatggc aattttgccc aagggaatgt atcctaatgg
     8701 cattcaaatg attgaaaaag acgagctcaa tgatatgact tgttttattg tggctaaacc
     8761 tgaagaagag gttagtgagc tacatttatt taaagatttg tatcaaattg gcagtcaatt
     8821 catcgcttct aactcggtcg aagaagcagc actgttggtc gcctctaggt ctggctattt
     8881 tattttaaat gagaatacgg ctaggttaat taatactaca gatttgcagc cacttttctt
     8941 gcttgatcat ggtcagttaa taaagcaaaa gataatggct ttttataagt caaattcagc
     9001 gttaagtagt gagtttataa agctattgca gcaagaatat taatctgtaa agttaaaaat
     9061 atcttgtcta agtactataa gatactgtaa aatatattat gaaagcggac tcatatattt
     9121 tacattctgg agatgatttt tatgctaaaa agaactttgt tacctttaac atcaatggta
     9181 cttgttttag gattaactgg tttggctagt caagttgaga ctgttgatgc ttcaacttat
     9241 ggtaatggtg tacaggttac tattccaaaa aagatgcagg gtacttggta ctcttatgat
     9301 cgtaatgcac ataatggcac aaagatcacc tttactgaac atactgttaa tggcaaacca
     9361 atatttaccc aggaggcttc gacaattagt gattacttca atggtagaat tgctaaccag
     9421 aagaactttg ataaggtaac gcaaaactgg atgtctggta aaactaccaa aatgaagaat
     9481 gatacattct atgagattga tccgtggatt acttttgaaa attggagtct ttatcgagtg
     9541 gtaccacaaa ccattaatgg taaaaagcat aacgtgctgg tttattctag tagatatgat
     9601 ggtggtaact acttcagaag caagaaatta gctaaaaaaa tgaaggacta caagtttaag
     9661 aaagttaatt acacgttata gttttgtgac atcccttaac taagggatgt tttttactaa
     9721 tagacgcgat aaaatttagt ataataatga caaaattaat tcttggagga gaagttatga
     9781 aattaaaaca aacaccaatt ttgcgtttat ataaactaga aactaataaa gaggatcatg
     9841 caaagttcgt taaggcaggg caacataata tgcttacttc tcaagaaaac gaaccaggca
     9901 cattgtttat gcagacaagt catgacgaag aaactactaa ttttgtagta gaatgctatc
     9961 aagacgaagc aagttatgat actcatgcta attcaaagca atttaaggat tttactgacg
    10021 ttgctaaaga tattttaact agtcgagtaa aggtagaatt gtttccggaa tttatttcta
    10081 caaaggcaga aaaactagca gttaccggat caaatgatta tgttatttat ctgactgaaa
    10141 ttggtgtttc tttaggtaag ggcgatgagt ttgctcatgc tgtaatgaaa gaaatgaaaa
    10201 cggcagtcga agaagaaaaa gatattttgg caatgattgc aggaactgtt gccgatcaac
    10261 caaatgaatg gttagctatt gaagtttatc gtaataatga agcttacaag cagcacttgg
    10321 aaactaagaa cttcaaagag tatttgaata atacaaaata ttgtgttgaa agtaagagtt
    10381 tacgtaagtt gcaaccagat gtaattgttg accaaggtgc aattttctac caaccataaa
    10441 gaataagacg aaaagaagac caggctatgt ggagtacata acctggtctt tctagttaga
    10501 ggggaaaaga tttattaaca tatattattc tggtttttag tggcgatgtt ttacctttgc
    10561 tactgctggt ttattaatta atactgagct gatggccatt aaaccaagcg ttaaaaatga
    10621 tccaccaatt aagagtagtt taatcaaggt tctcattcct ttcatcttaa ttgatcttat
    10681 aatagcgaaa taatattaag aatttatatg taaaacctaa tggattagtt aagaaaataa
    10741 aactagaaaa aaggctggtt agcacgtaaa atagaaatag agtcaaagtc tagtgcaact
    10801 gcgcataaaa taaagcagta tcgatgggat gctgcttgtt ttggttaaaa aatagagaat
    10861 atgcttgtag cccttttcgt aaatagcgtt aatgttgtaa aatggaaagt gcattaagtt
    10921 tattaatgag aaaattgatg tattattgca aaataggccg taatggccct ttttgttgtg
    10981 aaaaaattaa aagaatatag gattggaaat gccaggaata gtagagcaaa cattattaga
    11041 acaacaaaat attgatttaa atgaaatggt aacaatgaat caaatgattg atcaattgtt
    11101 gcctaatgca agtaaagaat tacaacaaaa actaaagatt aaaatttata actttgtgcg
    11161 tacacgtaaa caaccaagta ttactgtgcg aagaagaaaa tattttaagc cggctgttgc
    11221 taaattaatt attggtaatg tacaagatta cgcagatgca attgaacgtc gtgctaagga
    11281 agccccagct aaagaggatg ctactgataa gaggccagct tctaaatcta agcgggttaa
    11341 gacaattact aagcgtaaga ttttagctaa agttataaag aatgataaga ttgataaatc
    11401 tattcaaaag aaattagagg ataagattgc ttcaattgtg aagaccaact ttattaagcc
    11461 agttaacaag cggggaagtt tttcggttga agatggtgaa aaagttatag ctgaacttag
    11521 tcctttttat caaaatatca agattgatca aaagtatcgc aagaatgctg aaaaagcggc
    11581 tgaaaataag gaaacagaaa ctaaagaaaa gcctgagcaa cattctaagg atcagaatga
    11641 aagtcgtgaa ggtcaatcta aggactttga gcgtaagaat aatcagaaga atagcaataa
    11701 tcgaaataat aataatcaaa cgcaaaatca acgtaagcga caaaataagc atccttttga
    11761 gatcagaaga gaaaataata accgctcacg taataatcag tctaaccgcc gctataataa
    11821 tcgaaataat tatgataatc ggaataatta tgaatttgat gaagctagcg gtttgcgtga
    11881 acgctacaat acagtaatca gaaattacaa tcaactggag caaagatata atgctttgca
    11941 agataaatat aatcaggctt tagatgataa agctagattg atcgaagaaa tgggtaagaa
    12001 gaacgaagac ttacgtcgtg tattgatcga cgttttgcga aaaatgtagt ttttggtaaa
    12061 caaagagact agtagtcaat ttgaattgat tactagtctt attttatgtt tatgaaatat
    12121 gatttagctt aaaaattaaa aaaatatgtg taaaaaatta tttttgtgta gtaagattaa
    12181 aggatgataa atatttttat taatgattaa tggaggagaa gtatgagttt aaaagagcta
    12241 tttaaaagca atgtgtttcg aggaaactgt caaatctttt gtgtaaatag atttttctcg
    12301 tagattgatt ttttaatctt ttatttaatc aaagtaggat tctaaggtat cct
//
