LOCUS       c00081_gnlPro..        16940 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IHJAFLHK_109.
ACCESSION   c00081_gnlPro..
VERSION     c00081_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 17:21:37
            Original ID  :: gnl|Prokka|IHJAFLHK_109
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 6493
            Orig. end    :: 23433
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16940
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[16493:19028]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12535
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..16940
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16940
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             1441..2352
                     /locus_tag="ctg81_8"
                     /transl_table=11
                     /translation="MAYFDNGNQIFKDARKNHYAVGAYNTNNLEWTRAELRAAEETRTP
                     LLIQVSTGAAKYMGGYKFVKDMVADQMDSMNISVPVILNLDHGDFESAKECIALGYSSV
                     MFDGHALPTDENLAKTKEIIKLAHERGISVEAEIGKIGENQGGGELASVEDAKKFVAAG
                     VDKLACGIGNIHGVYPADWKGLNFDRLKEIAEAVPDTPLVLHGGSGIPEDQVKKAIKLG
                     IAKININTEFQLAFQEATRKYIEDEKDLDKKAKGYDPRKLLLPGAEAITAKMKEMISWM
                     GTKTIDDELKDASFDRSSLNEE"
     CDS             2498..3022
                     /locus_tag="ctg81_9"
                     /transl_table=11
                     /translation="MEEKMLNPFMPSFGRFPKIIIDQQEALTDYLTGLQTHDAKYQTSL
                     VYGTRGSGKTVFLLNVQRSLAKLDNWIFIRLNNGQGNLLFQLMHGLQRVAGISLVDLLK
                     SVKSLNIMGKGITWQALQESQQIDYDEYISILLSRLKKQGKSILIGIDEIEISDDVRAF
                     GSEYQTLIGDE"
     CDS             3038..3613
                     /locus_tag="ctg81_10"
                     /transl_table=11
                     /translation="MTGLPSRISEVQYDNTLTFLLRSNRVYLSPLDKKTIANSYEKAFT
                     KGKREIDFMVLDEMSRAVKGYAYAFQTIGYYAWRFSRELLQLNEEVLKQTIRAAKKDLF
                     RNAYERMYMDLSKNDRDFIEAIIKAGTDRVTTKQLQDILNKPINYISVYRARLLDDQLI
                     TSPQRGVVQLALPFFAEFVEKSNLEHLS"
     CDS             3617..3820
                     /locus_tag="ctg81_11"
                     /transl_table=11
                     /translation="MSKYNKLWQYIKDNKAGDFELSFDELGQQAGVALDHSFLRYKKEL
                     PAYGFEVQKISLKNKVVKFHQL"
     CDS             3940..4857
                     /locus_tag="ctg81_12"
                     /transl_table=11
                     /translation="MKKVLSWPVYYQLSEIYTAPLNVIWFVFGAAMSFQQYHMFNLINI
                     LLCLVDVFLFDLAVNIADNYYDYLHGKDRHFLTDINPIGRLKLPLTDVRNLVWISYFIS
                     AIPGIILVYRTGWPVLIMGVVGYFIGIFYTAGPKPLNATPICELVVSFFISYFIMLVSI
                     YVTIYGTYPLTWNLALTTLIRCLPLTLIFYALQLANNTCDLHEDLNNGRHTLASYTGKK
                     YALKIIKTLIIAGLLFPIIVVLFGLAKWPLIFSCFLLPILWQKLKQFFEHPDKQTTYLQ
                     MIKYLSIFFITYIAIYTVLVETVK"
     CDS             4974..6152
                     /locus_tag="ctg81_13"
                     /transl_table=11
                     /translation="MNDFTKDFAQALFNPDKINDLLRKELQQAVNNLLEAELTAFLGYD
                     PYARNGWNTGNSRNGAYFRKVDTQFGPIEVQVPRDRNGQFHQHTLPDYKQHSDILESMI
                     IKLYSKGVTTREIADLIEKMYGSHYSPAQVSNISKQMIPKVEAYHKRKLSDKFFCVYLD
                     ATYLPLRRETFEREAVYIAIGIKPNGHKEVIDYCIAPSENIEVWTDMLQNMKSRGLKQV
                     ELFLSDGVVGMKTALARTYPKAHFQRCLVHVMRNICAKVRVDDREKIMNEFKQVHQQTN
                     KEEATAVLHDFYTKWGKVYSHVIRSLKDIEPDLLVFYNYPKQIRASIYSTNMIESFNNV
                     IKRKAKPKAEFPTEQSLDAFIGIQAMSYNDRYFNRIHKGFGQVQDTLESYFE"
     CDS             6295..6609
                     /locus_tag="ctg81_14"
                     /transl_table=11
                     /translation="MKRCKNWVVTIVAFLMLVGEISVLPANLQGSTSVVNAAIHHRRRK
                     HQYRDKTKIYTSNYRIVDNKRSKIFHVMRGHNYRMNRENAVFFKSKAAARAAGYRESKR
                     "
     CDS             complement(6677..8950)
                     /locus_tag="ctg81_15"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGKVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNR"
     CDS             9079..9927
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg81_16"
                     /sec_met_domain="LysR_substrate (E-value: 6.6e-30,
                     bitscore: 94.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.1e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQQKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             10001..11230
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_17"
                     /sec_met_domain="Amidinotransf (E-value: 3.7e-109,
                     bitscore: 355.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELLTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             11241..11672
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_18"
                     /sec_met_domain="OTCace_N (E-value: 8.2e-38, bitscore:
                     120.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             11627..12535
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_19"
                     /sec_met_domain="OTCace (E-value: 7.4e-47, bitscore: 150.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 4e-20, bitscore: 63.1,
                     seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LEVGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQN
                     FAQDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTG
                     TPDDQLIFMHCLTAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHS
                     IKAVMAATLGNLFIPIACGGGGILVIVKDGHLRGVAGVIHKDFSAAKMAEDINADELVI
                     LTTVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGSMKPKIEAAIEFVEKTGNLA
                     IITSLSNANKLADGVGTIIYN"
     CDS             12549..13085
                     /locus_tag="ctg81_20"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDINMNI
                     PGPIKNNRYLTKMFMLGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFENQISLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             13201..14367
                     /locus_tag="ctg81_21"
                     /transl_table=11
                     /translation="MELKKNKNNLKQITALIQYAFLKNNDLTKDENFMSRYDHSTGYGY
                     FDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQLMKEILHDLHRQD
                     IPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIVRGKWDNLAVQNG
                     VIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERPISYLIYRIRDNT
                     FLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPEQNELQVDLRPYM
                     MSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRKVAVERKEDALVD
                     FSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDYF"
     CDS             14383..14544
                     /locus_tag="ctg81_22"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             14534..15151
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg81_23"
                     /sec_met_domain="LysR_substrate (E-value: 2.2e-12,
                     bitscore: 37.5, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNKMTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHD
                     GAFAKLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDM
                     TCFIVAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASRSGYFILNENTARLIN
                     TTDLQPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             15250..15789
                     /locus_tag="ctg81_24"
                     /transl_table=11
                     /translation="MLKRTLLPLTSMVLVLGLTGLASQVETVDASTYGNGVQVTIPKKM
                     QGTWYSYDRNAHNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWM
                     SGKTTKMKNDTFYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKL
                     AKKMKDYKFKKVNYTL"
     CDS             15885..16547
                     /locus_tag="ctg81_25"
                     /transl_table=11
                     /translation="MKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTSQENEPGTLFM
                     QTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVELFPEFISTKA
                     EKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAMIAGTVADQPN
                     EWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVDQGAIFYQP"
ORIGIN
        1 taacattgct aagccaatgt caatgggcca ccttcgttca actgtaattg gtaattcaat
       61 tgctaagaca atggagaagg ttggctatac tcctattaaa atcaattact taggtgacta
      121 tggtactcaa tttggtaagt tgattgctgc ctacaagcac tggggtaatg aagaagacgt
      181 taaaaaagat ccgattatga atcttttcca ctactatgta aagttccacc aagaagctga
      241 gaaaaatccc gaacttgata atgaaggtcg tgaatggttc aagaaacttg aagacgggga
      301 tccagaagca gttaaactat ggaaatggtt ccgtgaggtt tcattaaaag acttcaagcg
      361 aatttataaa gaactaggcg taacttttga ttcatacaat ggtgaagctt tctttaacga
      421 taagatgcaa ccagtaattg atgaattaaa agaaaaaggt cttcttcatg aatcacgtgg
      481 tgcgcaagtt gttgacatgg gtgaaggtga aaatcctgct attatcgtta aatctgatgg
      541 tacttcaatt tacttaactc gtgacctcgc cgctgctgaa tggagaatga aagaatataa
      601 cttcgttaag atgctttatg ttgtaggtaa cgagcaagcc caacactttg ttgaattgaa
      661 gactgttttg aaaaagatgg gttatgactg ggctgatgaa attcaccacg taccatttgg
      721 tttaatcacc caaggtggta aaaagttatc tactagaaaa ggtaacgttg tcttcctcga
      781 tcaagtatta aaggatgctg tttcacttgc taaaaaacaa attcaagaaa agaatccaga
      841 tttagcagat caagatcaag ttgctcatga tgttggtgtt ggtgccgttg tcttccacga
      901 tttgaagaat gatcgtttag acaattttga ctttgaccta gaagaagttg tgcgttttga
      961 aggcgatact ggtccttatg ttcaatacac taatgctcgg gcacaaagcg tcttacgtaa
     1021 ggccgctgcg atgggtgaaa atcctagcga aactgatcta gctcttgatg atgactgggc
     1081 ttttgccgta gccaaagatt tagcagattt cccaagaatt gtagctagaa gtgccgaaaa
     1141 gtttgaacct tcagtaatag ctaagtttgc cttagattta gctaaaaaac tcaataagta
     1201 ctatgctaat gtgaagattt taaccaagga cgataaaatt ggtgctcgtc tcgccttagt
     1261 tcaagcaaca tcaatcgttt taacggaatc acttagattg ttaggtgtca atgctcctaa
     1321 agaaatgtaa gagaaaaaca atgaaaataa gaaaataacg cttacattta gtgaaagatt
     1381 gttcataatt ccagaattag ggtacaatat gcatgtaaga tatttaggag gtatttttta
     1441 atggcttatt ttgacaacgg taatcaaatc tttaaagatg ctcgtaagaa ccattacgct
     1501 gtaggtgctt acaacactaa caacttggaa tggactcgtg cagaattacg tgctgctgaa
     1561 gaaactagaa ctccattgtt gatccaagta tcaactggtg ctgctaagta catgggtggt
     1621 tataagttcg ttaaggacat ggtagctgac caaatggatt caatgaacat ctcagttcca
     1681 gttatcttga acttggacca cggtgacttt gaatcagcta aggaatgtat tgctcttggt
     1741 tactcatcag ttatgtttga tggtcacgca cttccaactg atgaaaactt ggctaagact
     1801 aaggaaatca tcaagttagc tcatgaacgt ggtatttcag ttgaagctga aatcggtaag
     1861 attggtgaaa accaaggcgg cggtgaatta gcttctgttg aagatgctaa gaagttcgtt
     1921 gcagctggcg ttgacaagct tgcttgtggt attggtaaca tccacggtgt ttacccagca
     1981 gactggaagg gcttgaactt cgaccgtctt aaggaaattg ctgaagcagt tcctgacact
     2041 ccacttgtac ttcacggtgg ttcaggtatt cctgaagacc aagttaagaa ggctattaag
     2101 cttggtattg ctaagataaa catcaacact gaattccaat tagcattcca agaagctact
     2161 cgtaagtaca tcgaagacga aaaggacctt gacaagaagg ctaagggtta cgacccacgt
     2221 aagttgttat tgccaggtgc agaagcaatt accgccaaga tgaaggaaat gatttcttgg
     2281 atgggtacca agactatcga tgacgaactt aaggatgctt cattcgaccg ttcatcattg
     2341 aacgaagaat aatcatttga taattattta aataaagtct agcgtttgct aggctttatt
     2401 tttttaggca aatttggtga taacttaatt gaacctatta taaaagaaat ataaaataaa
     2461 aaattgaatt ataaagaaag tataaaaaga gacttttatg gaagaaaaaa tgttaaatcc
     2521 atttatgcct agctttggtc gttttcctaa aattattatt gatcagcaag aggcattaac
     2581 tgattactta actggcttac aaacgcacga tgctaagtat caaacttctt tagtctatgg
     2641 cacaagggga tctggaaaaa ctgtttttct tttaaatgtg cagagatctt tagcaaagct
     2701 agataattgg atatttattc gtttaaataa tggtcaagga aatttgcttt ttcaattaat
     2761 gcatggtttg caacgagttg caggtatttc gttagttgac ttgttaaaaa gtgttaaaag
     2821 tttgaatatt atgggaaagg gaattacttg gcaagcacta caagaatcac agcaaattga
     2881 ttatgatgag tatatttcaa ttttgctaag tcgattaaag aaacagggga aatcaatttt
     2941 aatcggaata gatgaaattg aaattagtga tgatgttcga gcttttggat cagaatatca
     3001 aacattgatt ggtgatgaat aagatatttc attattgatg acaggattgc caagcagaat
     3061 atccgaagta cagtatgata ataccctcac gtttttacta cgtagtaatc gtgtttattt
     3121 atcaccgttg gataaaaaaa caatagctaa tagctatgag aaagcattta ctaaaggaaa
     3181 acgtgaaatt gatttcatgg tattggatga aatgagccgt gcagttaaag gctatgctta
     3241 tgcctttcaa acgattggtt attatgcttg gcgatttagt cgggaattat tgcagttaaa
     3301 cgaagaagtt ttgaaacaaa caattcgagc tgcaaaaaag gaccttttta ggaatgccta
     3361 tgaaagaatg tatatggatc tttccaaaaa tgatcgcgat tttatcgaag caataatcaa
     3421 agctggaacc gatcgtgtca cgacaaaaca attgcaagat atcttaaaca agccgattaa
     3481 ttacatttcg gtatatcgag caaggctgtt agatgaccaa ttgattacat cccctcaaag
     3541 aggagtagta caattggcgt tgccattttt tgcagagttt gttgaaaaat ctaatttaga
     3601 acatttatct tagaaaatga gcaaatataa taaattatgg caatatatca aagataataa
     3661 ggctggggac tttgagcttt cttttgatga gcttggccag caggctgggg ttgccttaga
     3721 tcattccttt ttgcgttata aaaaagaatt accagcttat ggctttgagg tgcaaaaaat
     3781 ttcattgaag aataaagtgg tgaagtttca tcagttgtaa tgaaagctat taataactaa
     3841 agtagtagtt tgcgataata tcttcaaaat tagtaactat gttttgtttt agaaaaagac
     3901 taagatgtaa gtaaaaaatg ggaggattaa taagttacta tgaagaaggt tttatcttgg
     3961 ccagtatatt atcaactatc agagatttat acggcgccat taaatgtaat ttggtttgtc
     4021 tttggcgcgg caatgtcgtt tcaacaatat cacatgttta atttgattaa cattttactg
     4081 tgcttagtag atgtttttct gtttgattta gcagttaata ttgctgataa ttactatgat
     4141 tatcttcatg gcaaagatcg acattttttg actgatataa atccaattgg tcgtctgaag
     4201 ttacctttaa ctgatgttag aaacttagtg tggattagtt actttatttc ggcgattccg
     4261 ggtattattt tggtttatcg caccggctgg ccagtactaa taatgggagt tgtaggatat
     4321 ttcattggaa tattttacac tgcgggtcct aagccactga atgcaacacc gatctgtgaa
     4381 ttagtggtat ctttttttat ttcgtatttc attatgctag taagcatcta tgtcacaatt
     4441 tacggcactt atcctttgac ctggaactta gcattaacta ctctgataag atgtttgcct
     4501 ttaacactca ttttctatgc tttgcagtta gctaataata cttgtgattt gcatgaagat
     4561 ttaaacaatg ggcgccatac tttagccagt tatactggta aaaaatatgc tcttaaaata
     4621 attaagacgt tgattattgc gggattatta tttccaatta tcgttgttct ttttggttta
     4681 gcaaaatggc cattgatctt tagttgtttt ttgttgccaa tattatggca aaaattaaaa
     4741 caattttttg agcatccgga taaacaaact acctatttac aaatgattaa gtatttatca
     4801 atatttttca ttacatatat agctatttat acagttttgg tggagactgt aaaatagttt
     4861 gtgtaaggat gaatgattcc ttaaatttat ttctttaaac attagaaaaa ggagttcctt
     4921 tctcgtatga ttggtttgaa caaaaaaaca catacagaaa gaagaactcc ttcatgaatg
     4981 attttaccaa agattttgct caagctctat tcaatccaga caaaataaat gatttattgc
     5041 gcaaagagct acaacaggct gttaataact tgttagaagc tgaattgact gcctttctgg
     5101 gctatgatcc ctatgccaga aatggctgga atactggcaa ctctagaaat ggtgcttatt
     5161 tccgcaaagt tgatacgcaa tttggcccaa ttgaagtgca agtgcctcgg gatcgcaacg
     5221 gtcaatttca tcagcacacg ctgcctgact acaagcagca ctcggatatc ttggaaagca
     5281 tgattatcaa gctttactcc aagggcgtga ccaccaggga aatagccgat ctaattgaaa
     5341 agatgtatgg cagccattac agtccagctc aggtatcaaa tatttccaag cagatgattc
     5401 caaaggttga ggcttaccac aaacgcaagc taagcgacaa gtttttctgc gtctatttgg
     5461 atgcgacata ccttcctttg cgccgagaaa catttgagcg tgaagcagtc tatattgcca
     5521 ttggcatcaa gcctaatggg cacaaggagg tcattgacta ctgcattgca cctagcgaga
     5581 acattgaagt ctggacagat atgcttcaaa acatgaaatc ccgaggctta aagcaagttg
     5641 agctttttct ttctgatggt gttgttggca tgaaaacagc cttggccagg acttatccta
     5701 aagctcattt tcaacgctgt ttggttcatg tcatgcgcaa tatctgcgct aaagtacgcg
     5761 tcgacgatcg tgaaaagatc atgaacgaat tcaaacaggt gcatcaacag acaaacaaag
     5821 aagaagccac agctgtcctg catgacttct ataccaaatg gggcaaggtt tacagccatg
     5881 ttatcagaag cttgaaagac atagaaccag atctgctggt cttttataac tatcccaagc
     5941 agatcagagc ttcaatttat tcgactaaca tgattgaatc atttaacaat gtgatcaagc
     6001 gcaaagctaa gcctaaggca gagtttccaa ctgaacagtc gcttgatgct tttattggca
     6061 ttcaggcaat gagctacaat gaccgttatt tcaaccgaat tcataaaggc tttggtcagg
     6121 ttcaggatac cttagaatcc tactttgaat aaataattaa aaaatcaatt tacgagaaag
     6181 aactatttac acaaaagatt tgacagtttc aaactagttt ctaataaacg taggaacact
     6241 tcatatataa acgtatacta tataaatata gtgacatatt aagggagtgt ttttatgaaa
     6301 agatgcaaga attgggttgt gactattgtt gcatttctga tgttagtggg agaaatcagt
     6361 gttctgcctg caaatttgca ggggtcgaca tcagttgtta atgcagctat tcatcacaga
     6421 aggagaaagc atcaatatcg tgataaaact aagatttata ccagtaatta cagaattgtt
     6481 gataataaac gatcaaaaat ctttcacgta atgcgcggtc ataattatcg aatgaatcgt
     6541 gaaaatgcag ttttcttcaa gagtaaagca gcagcacgtg cagcaggata tcgtgaatca
     6601 aaaagataaa ttaaaagact tctaagagtt caaagttcct agaagtcttt taatttataa
     6661 aatttatggt aataatctac ctgtttttca tcacaggttg gtaaattaag tcgattatta
     6721 tggcagcaat aatcgctaca attacagtaa ttgctaagtt ttgaatggaa atctggacca
     6781 ttgcccaacc acaaagagct aagataaagg tcaatagaac atctgcaatt tgaacactac
     6841 caaccaactt ggatgggtaa tcttgccaaa agtacttacg agttctagta atcaaaacaa
     6901 tcaacattgc gctaagaact aggtatacgt aaaccatagt agaaacagca ccgtgactcc
     6961 aaccgtgtgt gtttaagaac caaacaaacc caataccaat taaagtccaa ccagcagcta
     7021 gtgaaaaggc gatcttagca agcttagcca tattccagtt ttctggctta taagtaatgt
     7081 gagtcctgtc agttccaatc atcatcgtaa ccatattgtt cataatggta tagataacca
     7141 ttgcattcaa ggccattggg atgtagtcaa agaaaagata gccaaaagtt aacagcatcg
     7201 ttaattcagc agttctagca agcttggtta gtgaccaagt agtcattctt tggtatacgc
     7261 gatgtccagc gtctaaaatt ttaacaattg agcctagacc atcgtctagt aataccattt
     7321 tacccgaacg cttagctacg tcagcagcat ttgaaactgc gattcctact tcagcttgtt
     7381 ttaatgcagg cgcgtcgtta actccgtcac ctgtcatccc tacgatatag cctttttctt
     7441 ggaaaagctt taccatcttg agtttatctt ctggtaaaac atcagcaata ccggccaaat
     7501 cattaatatc agtattttca ttgaaatcgt gaatcgaaat tactttacca gttaaatcaa
     7561 cttgttctgc cactgcagca gcggtctttt gattgtcacc agttaacata attgggcgaa
     7621 cgccacgttt cttgagttca gccaaagctg ctttagagtc tgttctaact ttatcttgta
     7681 agatgaagac accagctaac ttatcgtcaa tcaagactgc cactgagcgt cctgccttga
     7741 aattaattcc agaaatttct tcatcggcat gtttatcgat caaagataat tgcttaaatg
     7801 aaccaagctt tacattatgt ccagcaacat cagccataga ataaccagtg tcagaagtaa
     7861 atggagtaaa gttttcagca ttcatgactg gaatgttatt ttctactaag tattcatcga
     7921 ttgctgtatc gataatacca gcattacgtt tatcagttgc ggctccagct aaagcaagca
     7981 cgtctttgtc aggcaagtca cttagatcag tccaagcggc tacggcagtt ttgttttccg
     8041 taattgttcc agtcttatca agtaaaagca agttcaagtt agctgcgtcc tgaattccag
     8101 ttaggtcaga agtcaggact ccttctttac ttaagcgggt tgcttcaaat gagttggata
     8161 aagcaaaagt tgatggcatt gctacaggaa ttgaagcaat aaacatcatt gccaggaatg
     8221 gcaacatatt aataaaggta ttgaaattac cgcctttgaa gaaggaggcg ataataataa
     8281 ctaaggttaa aacaccatct agtaagcaaa ggtagtagat aatcttagtc aaaagttgtt
     8341 gtaagtgacc aggagcagcg gaattgttga tcaaattaat cgtcttaccg cttctagaat
     8401 ctttacctgt agcagtaaca acagctaggc catcaccttc aacaactgta gtaccggcaa
     8461 aggcggtgtc atcaattgct ttcttaactg gtttagattc acctgtaatt gagctttcat
     8521 cacaagctaa gttaccgtca acaattttaa catctgctgc gagtacgtcc ccgcgtttaa
     8581 gtgagattaa atcgccttta actagttgtt tagaatcaag tttgatccac ttgccatcgc
     8641 gttcaactga tacagtagga gtcaacttgt gtgaaatatt atttaaaact cgtcttgatt
     8701 gctttttctt agatgcaccg ttaaatgcag caaataaaag catcaacaac acgaataatg
     8761 attggaccca tttgcccaag atacattcta gaattaaagc agcttctaga atccaagcgg
     8821 ataggttcca taacttagac aagaactctt taaagaaatt gtattcaggc tctggtactt
     8881 catttaagcc atcttctttt aagcgcttgt ctgcttcggc ttgagttaag ccgtgaaatt
     8941 tatcagacat tattttccct ccaaatctac cttaataagg tagcacagat attgctatga
     9001 ataaaatact aaaatacaat ataagatatt aaatatttta atatcactat caattgaaat
     9061 aaaaaaagga taaataatat gaatctaaaa cagttacgtt attttctagt tgtagcagaa
     9121 gaaaagcaga ttacagcagc tgctaagcgc ttgtatattg cacagccacc attaagctat
     9181 caattaaaac aattagagaa agagttgggc gcgcaattat ttaaaagaac ggcacatggt
     9241 attgagctaa ctgatgtggg acaaattttt caaagctatg ccaatgaaat tatttctcta
     9301 gctcaaaatg ctgaaaacca agtacataag actatttccg gtgaattggg aacgattgca
     9361 attggaatgg catcttcctc aacgggcttg ataccaatga attcttttaa tgaattacga
     9421 aaatattatc cggaaatttc ttttgatatt tatgaagata atacttatgg catcctggat
     9481 aaattagaaa aaaagacaat cgatctaggc attgtacgaa cgccttacaa ccagacaggt
     9541 ttaaatacta agactttaac aactgaaaaa atgatggcta ttagtgtaga cccagatttt
     9601 cagcaaaaaa aagaattacg cattaaagat ctagcagatc agccattgat tatttatcgt
     9661 cgctttgagg atatttttaa tcaaactttt gcacatcatg ggcttaaacc attttatgcg
     9721 gttaagtgtg atgattcacg gacagcaatt acttgggcca agagaaaaat gggagtagcg
     9781 ctagtaccag aatcaattgc gacaacttat gcccaagaaa atatgatcgc aattaaacat
     9841 gctaattgga taacacattt gcagctggtt tggcgtaaag atcatcaagt tacaccttta
     9901 atgaaaaaaa tcattgctgc aatatgataa tactgtaact tttacctaat tgatccataa
     9961 taaatgtaaa cgggtacaat aattaataga aggtggttga atgtcgagtc cgattcatgt
    10021 ttattcagaa attggtaagt taaaaacggt gatgttacat cgaccgggaa aagaactaga
    10081 aaatctagcc ccagatattt tgcatcgaat gttgattgac gatattcctt atctgaagat
    10141 tgcccaagaa gaacatgatg cttttgcgca tgtattgagg cagcagggga tcaaagtatt
    10201 atatcttgag gatttattag cagaatcttt aacagatgag aaagttcgtc gggcattctt
    10261 agatcagtta ctggatgaat caagtattaa aaaacaggat cctttgcatc aattattgct
    10321 gaactatctc caagaattgc taactaagga aatggtaaaa acggtgattg ctggaattag
    10381 aaaaagtgcg attcataatt ctaccccatc tttagcagat ttggctgagg acccagatta
    10441 ccctttttat cttgatccaa tgccaaatgt atattttact cgagatcaac aggctgcaat
    10501 tggttcaggg atgaccatta accggatgac tttcagagct agacgacgtg aatcattatt
    10561 tatggaaaca attttgaaaa atcatcctga tttcaagaac gcaactattc cagtttggcg
    10621 tgaccgttat catcatggtc gccttgaggg cggggatgaa ctagttctaa ataaccatgt
    10681 gttagctgta ggtatttcac aacgcacttc tgcaactgca attactgact tagctcataa
    10741 tttatttgat cattcaagtt atgatacgat tttagcgatt aagattccgc acaatcatgc
    10801 tatgatgcac cttgatacag tttttacaat gattaattat aatcaattta cggttcatcc
    10861 ctttatttta gataaagccg gcaaaattga tatttatgtt ctacagcccg atgatcacaa
    10921 cggtgtaaaa atcacagaaa agaatgattt ggtgcaggtt ttgaaagaaa acttacattt
    10981 aagcgaattg gatttaattc caactggtgg tggtgatcca attgccgcac cacgtgaaca
    11041 atggaatgac ggctcaaata ccttggcaat tgcaccaggt gaagtcgtta cttatgatcg
    11101 taattatgta tccaatgatt tgctaagaaa acatggcatc atcgttcatg agattcggtc
    11161 tagtgaactc tcacgtggtc gtggcggtcc tagatgtatg tcgtgtccgt tgattcgtga
    11221 agatttataa gaggcaaaaa atgaaatatt tacaaaatgt ttttcaaggt agaagttttc
    11281 tcgattgtaa agactatact ccagctgaaa tttcatattt aattgatttt gcattacatt
    11341 taaaagaact taaaaaagag catatcccac atgaatatct gaaaggtaaa aatattgcac
    11401 tactttttga aaaagcctca actaggacgc gatctgcttt tgtagtagct tgtaatgatt
    11461 taggtgctca tccagaatat ctaggcgcaa gcgagatcca cttaggtaaa aaagaaagcg
    11521 tcaaggatac ggctaaagtc ctaggctcaa tgtatgatgg aattgaatat cgcggttttg
    11581 ctcaagaaga tgtagaagag ctggctaaat attctggcgt tcctgtttgg aagtgggtga
    11641 tggccgcgat aatgttgccg acagtctttt agtttgtggc tcaatgttag gtgttaatgt
    11701 acatattgtt acacccaagc ctttgtttac acatcctgat gtacaaaaaa ttgctcaaaa
    11761 ttttgcccaa gattcaggtt caaaaaattt gatcacagat gatattgctc aaggcgttaa
    11821 aggagccaat gttgtttata ccgatgtttg ggtttcgatg ggtgaaaatg attggtctga
    11881 acgaattaaa ttattaaagc catatacggt cacaatgaaa atgatgcaaa tgactggtac
    11941 accagatgac caattgatct ttatgcattg tttgacagct tttcatgatc gaacaactca
    12001 ggtgggagaa gaaatctatg aaaaatatgg cttaaatgag atggaagtaa ctgatgaggt
    12061 ctttaattca aagtatgctt ggcaatttac agaagctgaa aatcgattgc attcaattaa
    12121 agcagtgatg gcggctactt taggaaattt atttattccg attgcctgtg gcggtggtgg
    12181 catccttgtt attgtgaaag atgggcatct cagaggtgtt gccggcgtaa ttcataaaga
    12241 tttttccgct gctaaaatgg cagaagatat caacgctgat gaattagtaa ttctaacaac
    12301 ggtggatcat gcatttttga attatggcaa agaaaatcaa caagcaattg gtaaaataaa
    12361 agttgaacag ctcaaacaat atctagcagc aggttatttc gcagctggga gtatgaagcc
    12421 taagatagaa gctgcaattg aatttgtaga aaaaacaggt aatttagcaa ttatcacctc
    12481 tttgagcaat gccaacaaac tagcagacgg agtcggcaca atcatttata attaactggg
    12541 tgataaaaat gaatattttt aatgaaggaa aaaagcagga tattgcccaa gttttagcag
    12601 ctaaagatag gcgagtagct gtacaacata agatttttaa taagtatcct aatcaaactc
    12661 tagtcgacat taatatgaat atcccaggac caatcaagaa taatcgctat ttaactaaaa
    12721 tgtttatgtt gggtatcaat gagctggaaa atgcttggac taacctaggt tatcatttta
    12781 aattggtgac acagcttaat gatgatagtg gctgtgaaaa cttttatgta ttatctttgt
    12841 caattgaaaa agtaaagcgc tcaacaattg attttgagaa tcagatatca ttgggacgtc
    12901 tctttgatgc agacgtgttg gtaaaaaata aacaagctgc aatttcacgc agagatttgg
    12961 gcaggcagcc acgtaagtgc tttttatgtg atcgccctgc taaagaatgt gctcgtagcc
    13021 ggagacattc agtggaacag atgcaggcat ttatctctca gctttatcaa gaatacgttg
    13081 cgtaaaataa accgggattt tatgattccg gtttattttt atgaaaaatc tagttaaaaa
    13141 tttaaaaaat gaactaaaat agtaatgaat aaatttatag atgtacgtat aggaataagc
    13201 atggaattaa agaaaaataa gaataattta aagcaaatta cggcattaat tcaatatgca
    13261 tttttgaaaa ataatgattt gactaaagac gaaaatttta tgagtcgtta tgatcatagt
    13321 acaggttatg gctattttga taaggaaaaa ttagctagct atattatggt taatcgattt
    13381 aaaagtgatg tttttgggca tcatttaccg atggctggaa taggttatgt agcttcatat
    13441 cctgagtatc gtggccaagg tcatatttcc caattaatga aagaaatttt gcatgactta
    13501 cataggcaag atattccgtt tgctaacctg gcaccatttt cggagagctt ttatcgccag
    13561 tacgggttta gcaatagtat ttatcaaaaa gaatatcgct ttgatggaag cgcattgcgt
    13621 agttttaaat taccacgttc tggtcatata gtgcgtggca agtgggacaa tttagctgtt
    13681 caaaatggtg tgattcaact ttatgaacgt caactgcata ctgatgatga acgtaacacg
    13741 gttgtacgtg aggcatggtg gtggaataga cttgattctt attatcatca ccgcaatgta
    13801 gccgtttatt ttgacgcgga tgagcggcca attagttact tgatttatcg cattagagac
    13861 aatacttttt tagctgatga aatgtacgca attacgccgc agggattact gagtatgttt
    13921 ggttttatgg gttcgcacgc gggcagtgtt aagcaattta aaatgagcgt accagagaaa
    13981 tcgttacgag ctgaactttt tcctgaacaa aacgaactcc aagttgattt gcgtccttat
    14041 atgatgagtc gaattattga ttttgaaaaa gttttggctt gtatgcggcc aatgcaagaa
    14101 ggtgatttta atctggaagt caatagcgat gaacagtgtc cttggaatat tggagtttgg
    14161 caattaagta atcatggacg taaggtagcg gtagaacgta aggaagatgc attggttgat
    14221 ttttcgggat caattaccgc gtggacccag gtgctattag gtagactaac catgaatgct
    14281 gctgttaaac taggattaat tacagattac cgcatcaaaa aattagattt cgttaaaggc
    14341 gatgtatcat tttatgatta tttttagttg tgaggttaaa aaatgagtaa agaaaagaaa
    14401 ctcaatttaa taaaattatt tggcattgta gttagtggtt tgaatttgat cttttttgcc
    14461 ttgatggcac ttaataagca tgaagatact aaggataaaa gaagagtagc agaagaagga
    14521 cacgcaccgc tggatgaaaa ataaaatgac ggaattaaag attgcatatt ttgaccaatt
    14581 aggtcgtaag gaattagatc aggcagtgca gcattttgtg ttaaaacatc ctaatgtaga
    14641 tgtaaaacta cttgcgacta gtcatgatgg tgcttttgca aaactgaatg aagatgaagc
    14701 agacatagca atcaatgatt tgcgtgacga gaatcttaac tttgatgaaa cagaattgac
    14761 tcaagctggt gtaatggcaa ttttgcccaa gggaatgtat cctaatggca ttcaaatgat
    14821 tgaaaaagac gagctcaatg atatgacttg ttttattgtg gctaaacctg aagaagaggt
    14881 tagtgagcta catttattta aagatttgta tcaaattggc agtcaattca tcgcttctaa
    14941 ctcggtcgaa gaagcagcac tgttggtcgc ctctaggtct ggctatttta ttttaaatga
    15001 gaatacggct aggttaatta atactacaga tttgcagcca cttttcttgc ttgatcatgg
    15061 tcagttaata aagcaaaaga taatggcttt ttataagtca aattcagcgt taagtagtga
    15121 gtttataaag ctattgcagc aagaatatta atctgtaaag ttaaaaatat cttgtctaag
    15181 tactataaga tactgtaaaa tatattatga aagcggactc atatatttta cattctggag
    15241 atgattttta tgctaaaaag aactttgtta cctttaacat caatggtact tgttttagga
    15301 ttaactggtt tggctagtca agttgagact gttgatgctt caacttatgg taatggtgta
    15361 caggttacta ttccaaaaaa gatgcagggt acttggtact cttatgatcg taatgcacat
    15421 aatggcacaa agatcacctt tactgaacat actgttaatg gcaaaccaat atttacccag
    15481 gaggcttcga caattagtga ttacttcaat ggtagaattg ctaaccagaa gaactttgat
    15541 aaggtaacgc aaaactggat gtctggtaaa actaccaaaa tgaagaatga tacattctat
    15601 gagattgatc cgtggattac ttttgaaaat tggagtcttt atcgagtggt accacaaacc
    15661 attaatggta aaaagcataa cgtgctggtt tattctagta gatatgatgg tggtaactac
    15721 ttcagaagca agaaattagc taaaaaaatg aaggactaca agtttaagaa agttaattac
    15781 acgttatagt tttgtgacat cccttaacta agggatgttt tttactaata gacgcgataa
    15841 aatttagtat aataatgaca aaattaattc ttggaggaga agttatgaaa ttaaaacaaa
    15901 caccaatttt gcgtttatat aaactagaaa ctaataaaga ggatcatgca aagttcgtta
    15961 aggcagggca acataatatg cttacttctc aagaaaacga accaggcaca ttgtttatgc
    16021 agacaagtca tgacgaagaa actactaatt ttgtagtaga atgctatcaa gacgaagcaa
    16081 gttatgatac tcatgctaat tcaaagcaat ttaaggattt tactgacgtt gctaaagata
    16141 ttttaactag tcgagtaaag gtagaattgt ttccggaatt tatttctaca aaggcagaaa
    16201 aactagcagt taccggatca aatgattatg ttatttatct gactgaaatt ggtgtttctt
    16261 taggtaaggg cgatgagttt gctcatgctg taatgaaaga aatgaaaacg gcagtcgaag
    16321 aagaaaaaga tattttggca atgattgcag gaactgttgc cgatcaacca aatgaatggt
    16381 tagctattga agtttatcgt aataatgaag cttacaagca gcacttggaa actaagaact
    16441 tcaaagagta tttgaataat acaaaatatt gtgttgaaag taagagttta cgtaagttgc
    16501 aaccagatgt aattgttgac caaggtgcaa ttttctacca accataaaga ataagacgaa
    16561 aagaagacca ggctatgtgg agtacataac ctggtctttc tagttagagg ggaaaagatt
    16621 tattaacata tattattctg gtttttagtg gcgatgtttt acctttgcta ctgctggttt
    16681 attaattaat actgagctga tggccattaa accaagcgtt aaaaatgatc caccaattaa
    16741 gagtagttta atcaaggttc tcattccttt catcttaatt gatcttataa tagcgaaata
    16801 atattaagaa tttatatgta aaacctaatg gattagttaa gaaaataaaa ctagaaaaaa
    16861 ggctgaaact gtcaaatctt ttgtgtaaat agttctttct cgtaaattga ttttttaatt
    16921 atttatttaa tcaaagtagg
//
