LOCUS       c00183_gnlPro..        16287 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFJLHEIO_184.
ACCESSION   c00183_gnlPro..
VERSION     c00183_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:33:49
            Original ID  :: gnl|Prokka|PFJLHEIO_184
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16287
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16287
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8412:11961](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(8413..11961)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16287
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16287
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             298..3135
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 61.6; E-value: 2.8e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg183_1"
                     /sec_met_domain="Peripla_BP_1 (E-value: 4.5e-20, bitscore:
                     61.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRMMGYTKWIAVLLCLLGMTACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDEGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNFPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRI
                     APGAYQAAKKVGREKEMIFVGIDALPGKGNGLEMVLDSVLNATFIYPTNGDKVMQLAMN
                     ILEKKPYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRAKNRLNKELSEQKKQLEEQRDKLEEQRDQLEEQRD
                     KLEEQRDQLIQLSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADHTLSGDQH
                     RMLMLIQRNVNILLRLVNQILDFRKYENGKMEYTPVQVDVLSSFEDWNESFLAAARKKH
                     IHFSFDNMPDTDYHTLADMEKLERIYFNLLSNAFKFTPENGKITVRLSSLTKEDTRWIR
                     FTVANTGSMISAEHIRSIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTISVESDEKQG
                     TVFTVDLPVQTCETILAEDTLMSSVSSVPLNPAFPGSPASSNLNETLAVEEEELEKGYD
                     SSKPSVLVIDDNADIRSYVRGLLHTDYTVIEAADGSEGIRKAMKYVPDLIISDVMMPGI
                     DGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYISKPFSSQLLLARVRN
                     LIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGDSNLNVEDLGKDMGLS
                     RVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGYEVGFSSPSYFTKCYR
                     EQFGESPTDLLKRKG"
     CDS             complement(3216..4604)
                     /locus_tag="ctg183_2"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLFGV
                     FAFSSCEKNLYDESKQPEKEIQVKDLNIPAGFQWKLTQVAAGTVAATTPTMVSFFLDEA
                     CSKEEKIADIPVDTEISSLPLSIPTYVNTLYAQYKTSTNEIKKVAIPVNADRSFSLNIA
                     NDAKSKSNTTRSITRGHDIEDDIQLSKGVISHPKDGWGTIMFEDQFPSLGDYDFNDFVV
                     NYKVQFQGIKKVDKKYTAQYIQIGLRLKAIGGIFPYSPYLRLKEIDSDEVESIEVYETK
                     NVIPAIDGVDLVPNKHLIIDYSPLIKNLAKPAGSQYYNTEKNALVATSDLPEINILITL
                     KKRKEVKEILEGDEFDLYLKRNDSGTEIHMNGIEPITYQYPFNDKNLLPVYTNGDEEDD
                     NYYFSAGRLIWGLRVPGNAAHAIEKANFLEAFKGFAKWAQSSGKNEQNWYNQGNADKSL
                     LIHN"
     CDS             4688..5026
                     /locus_tag="ctg183_3"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMPQ
                     CSRMVGRALKQIPDDLSVPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVSE"
     CDS             5326..6552
                     /locus_tag="ctg183_4"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGHEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTAGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSRQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETHEFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             6549..7373
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 90.2; E-value: 4.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg183_5"
                     /sec_met_domain="BPD_transp_1 (E-value: 7.5e-29, bitscore:
                     90.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMVHFSTFFDAVNAGIGSFIIGFQHVLFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVSKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             7394..8260
                     /locus_tag="ctg183_6"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAILLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRQLVDSW
                     IPKSENK"
     CDS             complement(8413..11961)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg183_7"
                     /sec_met_domain="PFOR_II (E-value: 5.5e-19, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 6.4e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 5.7e-32, bitscore: 100.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.3e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.2e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.3e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.4e-25, bitscore: 78.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDYLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDNPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     EQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTAKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAQAENWTYCAENVKTKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIAADCTPAEVKELFAEWINNMLDADKTKE
                     LAAKIIPVVEANKDKCNHCKQIAELQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGAE"
     CDS             complement(11994..13172)
                     /locus_tag="ctg183_8"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             13335..14537
                     /locus_tag="ctg183_9"
                     /transl_table=11
                     /translation="MTKKALYIFNPEHDLALASGETNYMAPASARRMASELALLPMWYA
                     EEGSAVLAPSAYNLGYVKKIQELLGLSVDLMTEPELAIEPNLDIRPWGWDVALRKRLSG
                     LGMDEALLPSMEQLDGLREYSHRSKAVSLLPELQLNEYFCGESYYLKTQEEWKTFVEER
                     ECCLLKAPLSGSGKGLNWCKGIFTPFISGWCTRVAASQGGIIAEPIYNKVEDFAMEFYS
                     DGTGEVTFMGYSLFYTGKSGMYEGNRLLSNEAIWKQLSQYVPSKVLTDLENCLKYRLSA
                     LVGTVYKGYLGVDMMICRFPENEKPVFRIHPCVEINLRMNMGVVARFLYDRYVRSGSTG
                     RFVIDYHPSEGEALQEHERMSATYPLEIREGRVYSGYLPLVPVHRRSCYRAWIWVTPDN
                     I"
     CDS             complement(14548..16104)
                     /locus_tag="ctg183_10"
                     /transl_table=11
                     /translation="MNDLLRKLPIGIQTFEKLRKGDYLYVDKTELVWKIAYTSTPYFLS
                     RPRRFGKSLLLSTFEAYFEGKKELFEGLAIEKLETKWEKHPVLHLDLNAEKYDSPERLY
                     DILSRQLTLWEIQYGKGIDENTLSGRFSGVIRRAYEQTGSSVVVLVDEYDKPLLQALGN
                     DVLLDEYRKTLKAFYGVLKSADRYLRFVFLTGVTKFSQVSVFSDLNQLQDITLWPDYGT
                     LCGITLQELLDTFQPEIKILAANNSISYDDAVQRMTRLYDGYHFCINSVGIFNPFSVLN
                     VLKSKVFDNYWFQTGTPTFLVEMLQETEYDLRTLLDGIEAPSSMFSEYRVDSNNPIPLI
                     YQSGYLTIKDFDREFGNYLLQFPNDEVRYGFINFLVPFYTGVRNSDQGFYIGKFVQELR
                     SGDYDAFLTRLQAFFADFTYELNEQTERHYQVVFYIVFKLMGQFTDAEVRSARGRADAV
                     VKTPKYIYVFEFKLHDTAEAALKQIDDKGYLIPYQADGREVIKIGVEFSAEKRNISRWL
                     V"
ORIGIN
        1 cctttgttaa ccttaaatct aatactatga aaaacacatt gcaaagatac ggacttctgc
       61 taaatctgca aataatccaa ataaaaagag atgttttata acatttattg agtgtttgtc
      121 ttacgcttta tacttttgtt aataatttcc gattgaatat tgggaactgt tttgcatttc
      181 tttggagggt aatgatgaga ataattgggt gatagatagc atactcacag ttttatttct
      241 tatttttgtt ctcaatcgtc tatttaggtc atagaaagaa atacgaaaaa aatgagaatg
      301 attagaatga tgggatatac gaagtggata gcagtcttgc tctgtcttct tggcatgacg
      361 gcttgtcggc aggatgcacc gcgtttccgt atcggggtgg cgcaatgcag cgatgactcc
      421 tggcggcata agatgaatga tgaaattctc cgcgaagcaa tgttttatga tggagtatcg
      481 gttgaaatcc ggtcggctgc ggatgataat cgtaaacagg cggaagacgt tcattatttt
      541 atagatgaag gggttgactt attgattatc tctgccaacg aagcggcccc catgactccg
      601 attgtagagg aagcctatca aaagggaata cctgtcatcc tggtagaccg gaagattctt
      661 tctgataaat atactgccta tatcggtgcc gacaattatg aaataggacg tgcggtaggc
      721 aattatattg cgtcaagctt gaaaggaaaa gggaatgtgg tggaacttac cggactgggt
      781 ggctcaactc ctgccatgga acgccatcaa ggatttatgg ctgctatcag taactttccg
      841 gatatcaaac tgattgataa agcggatgct gcgtgggagc gtgaaccggc ggaagtggaa
      901 atggatagta tgctccgtcg gcatccgaag atagacgccg tgtatgcgca taatgaccgt
      961 attgctccgg gagcttatca ggctgcaaag aaagtgggac gggagaagga aatgattttt
     1021 gtcggtatcg atgctctccc cggcaaaggt aacggattgg aaatggtgct cgacagtgtg
     1081 ttgaatgcta cttttattta tccgaccaat ggcgacaaag tgatgcaact ggcaatgaat
     1141 atccttgaga aaaagcctta tccccgggaa acggtcatga acactgcggt ggtcgaccgt
     1201 acaaatgcgc atgtcatgca acttcagaca actcatatct cggaactgga tcagaagatt
     1261 gaaacattga acggacgtat cggcggatat ctgtctcggg ttgctacaca gcaggtggtg
     1321 atgtatggtg gtttggtcat tcttctattg gtggcaggtt tattattggt agtctataaa
     1381 tctcttcgtg ctaaaaatcg tctgaataag gaactttccg agcagaagaa acagctggaa
     1441 gaacaacggg acaagttaga ggaacaacgt gaccaattag aagaacagcg ggacaaactg
     1501 gaagagcaac gggatcagct catccagctt tctcatcaac tggaagaggc aacgcatgcc
     1561 aaactggttt tcttcacaaa tatatctcac gatttccgta ctccgcttac attggttgcc
     1621 gatccggtag aacatttatt ggccgatcat acactaagtg gagatcagca tcgaatgttg
     1681 atgctgattc aacgaaacgt gaatatcctt ttacgtcttg tcaatcagat tctggatttc
     1741 cgtaaatacg agaacggtaa gatggaatat acacctgttc aggtagatgt tctttcctct
     1801 tttgaggact ggaacgaatc attccttgca gcggcccgga agaaacacat tcatttctct
     1861 tttgataata tgccggatac ggattaccat acattggcgg atatggaaaa gttggaacgt
     1921 atttatttta atcttctttc caacgcgttc aagttcacac cggaaaatgg aaagataacg
     1981 gttcgtttat cttccttaac gaaagaggat actcgctgga ttcgttttac tgttgccaat
     2041 accggttcaa tgatttccgc cgaacatatt cggagcattt tcgatcgttt ttataaaata
     2101 gacatgcacc atgccggttc gggaatcgga cttgcattgg tcaaagcttt cgttgaattg
     2161 cataaaggta caatttctgt ggaaagtgat gaaaagcagg gcactgtctt taccgttgat
     2221 ttaccggtac agacttgtga aactattctg gccgaagata ctctaatgtc atcagtctct
     2281 tcagttcctt taaatcctgc ttttcccgga tctcccgcct cttccaacct gaatgaaact
     2341 ttagctgtcg aagaagagga actggaaaaa ggctatgatt cttccaagcc ttccgttttg
     2401 gtaattgatg ataatgcaga tatccgttcg tatgtacgcg gattactcca taccgattat
     2461 actgtaattg aagcagcaga cggttcggag ggcatccgca aagcaatgaa atatgtcccg
     2521 gacttgataa tctctgatgt gatgatgcct ggtattgatg gaatagagtg ttgccgtcgg
     2581 ctgaaaagcg aactgcaaac ctgtcatatc cctgtcatct tattgacagc ctgttctttg
     2641 gatgaacaac ggattcaggg gtatgacgga ggtgcagatt cttatatctc caagcccttc
     2701 agttcgcaat tgctgttggc acgcgttcgt aatctgatag attcacatcg ccgcctgaaa
     2761 cagttctttg gtgacggaca aacgttggcg aaagaggatg tctgtgatat ggataaagac
     2821 tttgtggaaa aattcaaggc tttgattgaa gcaaagatgg gagactcaaa tttgaatgta
     2881 gaagatttgg gtaaggatat gggattaagt cgtgtgcagc tctatcgcaa aataaaatcc
     2941 ctgactaatt attctccgaa tgaattgctt cgtatcgctc gtttaaagaa agctgcttcc
     3001 ttgcttgctt cgtcggatat gacagtggca gagattggtt atgaagttgg ttttagttct
     3061 ccttcttatt ttaccaaatg ttatagagag cagtttggcg aaagtccgac agatttgctg
     3121 aaaaggaaag gatagaatca aaactattca cgtcagaata caataaatcc cggtaacttg
     3181 aattttcaat gtttaccggg atttattgat atgtgttagt tatgaatcaa taaactttta
     3241 tctgcgtttc cttgattata ccagttttgt tcgtttttgc cactactttg cgcccatttt
     3301 gcaaatcctt taaaggcttc caagaaatta gctttttcaa tagcatgcgc tgcgttgcct
     3361 ggtactctta atccccaaat caggcgtcct gcactaaaat aataattatc atcttcttcg
     3421 tccccgtttg tatataccgg tagcagattt ttatcattga atggatattg gtaagtgatc
     3481 ggttcaatac cattcatatg gatttctgtt ccgctatcat tacgttttaa atacaagtcg
     3541 aattcatcgc cttctaatat ttcctttact tcttttctct tctttagggt gatcagaata
     3601 ttgatctccg gtaaatcact tgttgctacc aaagcattct tttctgtatt ataatattgg
     3661 ctgcctgcag gtttagccag attcttaatt aaagggctgt aatcaatgat aagatgttta
     3721 ttggggacaa gatctactcc gtcgatcgca ggaatcacgt ttttagtttc ataaacttct
     3781 atactttcca cttcgtcaga atctatttct ttcagtctta aataaggaga ataagggaat
     3841 attcctccga tagcttttag acgtaatcct atttgtatat actgcgcagt gtattttttg
     3901 tcaacctttt taataccttg gaactgcacc ttataattga ctacaaaatc attaaagtca
     3961 taatctccta atgatgggaa ttggtcttca aacatgattg ttccccaacc atctttggga
     4021 tgagaaatga ctccttttga caattggatg tcatcttcta tatcatgccc acgagtgatt
     4081 gaccgggtgg tgttagattt ggatttggca tcattagcaa tgttcagtga gaaacttcta
     4141 tctgcattta caggtatggc tacttttttg atttcattgg tgctggtttt gtactgggca
     4201 tacaatgtat ttacgtaggt tgggatgctc aaagggagac ttgaaatttc tgtatctaca
     4261 ggaatgtcgg ctattttctc ttctttacta catgcttcat ccaaaaagaa ggaaaccata
     4321 gtgggggtag tagcagctac tgttcctgcg gctacttgag ttaatttcca ttgaaagcct
     4381 gcgggtatat tcaggtcttt tacttgaatt tctttttcgg gttgtttact ttcatcataa
     4441 aggttcttct cacaggagct gaaagcgaat actccaaata aacaagaagc gaatagaatt
     4501 gtcttctttt tcataacagc agtgcttgtt ttgttaataa tagggttgct tttaatgggt
     4561 acaaaggtcg ggattatttg taaataaagc aaataaagtt gcatatttta tttgaaatac
     4621 ttttattatt tgcaaattct ttccttttta tctagttttg gaactgaaat aaagtaatgt
     4681 ttgagtgatg aaagattata aagtagacaa agcgagtctc tccgcatcct tttgtcaaga
     4741 ggtgtatcag gttgttcggg aaattccggt aggtaaagtt tctacctatg ggggaattgc
     4801 cgcattattg ggaatgcctc aatgttcccg tatggtgggg cgtgctttga aacagattcc
     4861 ggatgattta tctgtgcctt gtcaccgggt tgtcaatgca tcgggacgcc ttgttccggg
     4921 ttggacagag cagaaacaac tcttgttgga agaagggatc tctttcaagc aaaatggatg
     4981 cgtagacttg aaaaagcatc tttggaatta ctccgtatct gaatgaaatt tgcatattta
     5041 atctattttc cttatctttg tgccaacaat atgcaagaac agactgttat ttatttatga
     5101 aaatactgtt ttctactgtt cattgagagg ataatcttat caaattctat tccttttaaa
     5161 ctactcagtc tgtcttttta aaccatttta aaaaacgtcg gatcgtcatg ttgtcatgtg
     5221 acatgattga accatgcgaa cattcaactt gtttatcgta agtgagaatg aggaacgcgg
     5281 cagttgaaaa caaaacaact attataatct aaaccaatat attatatgag taaaatagaa
     5341 ataaaggatt tgtaccttat ctttggtcac gagaagcaga aagcactcaa gatgttgaaa
     5401 aaagataaga gtaaagagga aattctgaaa gataccggtt gtacggtagg agtgaaagat
     5461 gccaatcttt caattaatga aggagagttt tttgtgataa tgggactctc gggaagtgga
     5521 aaatcgacat tactgcgttg tatcaatcgt ctgatacgtc ctactgccgg acaagtgctt
     5581 gtaaacggag tagatatatc taaaatatcc gaaaaagagt tattgcaagt tcgccggaaa
     5641 gagttggcga tggttttcca gaatttcggt ctgttacctc accgttccgt attgagcaat
     5701 atcgcgttcg gtctcgaact tcagggagtg aagaaagagg aacgtgagaa gaaagcgatg
     5761 gaaagtatga agcttgtcgg attgaaagga tatgaaaatc agatggtggg cgagctttcc
     5821 ggtggaatgc aacagcgtgt cggactggcc cgtgctctgg ctaataatcc cgaagtgctt
     5881 ttaatggatg aggctttctc tgcgctcgat cctctgattc gtgtgcaaat gcaggatgaa
     5941 ctgctggctt tgcagtcgaa gatgaaaaaa acaattgtct ttattaccca tgacttgagt
     6001 gaagcgatta aactgggcga ccgtattgcc attatgaaag acggagaggt ggtgcaggta
     6061 ggtacttcag aagaaatact gaccgaaccg gctaacgatt atgtagcccg ttttgttgaa
     6121 aacgtggaca ggagtaaaat tatcaccgct tcttctttaa tgattgacaa accactggtg
     6181 gcccgtctga agaaagaggg acctgaagta ttgattcgta agatgcgtgc gaagaatatc
     6241 accgtattac ctgtcataga cgccgatgat aaactggtcg gagaagtacg tctgaacgac
     6301 ctgcttaagt tacgtagcag acaggaaaaa tccattgaaa cgattgtgcg tacagaagta
     6361 cattctgtat tggaggatac agtgttggag gatatacttc ctttaatgac aaagagcaat
     6421 tcgccggtat gggtgattga tgagacgcat gagtttttag gaacaatccc gctttcctcc
     6481 ttaatcatcg aagtgacggg gaaagataaa gaagaaataa acgaaataat tcaaaacgca
     6541 atagatttat gataaatata ggacaatata tagagatggc catcaattgg atgatggtac
     6601 atttttccac tttctttgat gccgtgaatg caggcatcgg tagttttatt ataggattcc
     6661 aacacgtact ttttggaata cctttttata taaccattct agtgcttgct gcactcgcat
     6721 ggatgaaggc aggacgtggt acggcaattt tcaccgcatt aggattatta ctgatttatg
     6781 gaatgggatt ttgggaggct actatgcaaa ccctggctct cgttttttca tctacctgtc
     6841 tggctctgat tgttggtgta cctttaggag tgtggacggc aaacagtccg cgtgcagaga
     6901 aaatacttcg tcctgttctc gacttgatgc agacgatgcc tgcttttgtt tatctgattc
     6961 ctgccgtttt gtttttcgga ttgggagcag tgccgggagt gtttgccacc attatctttg
     7021 ctatgcctcc tgtggtccgc cttactggat tgggaattcg gcaagtttct aaaaatgtag
     7081 tggaagcttc ccgttcgttc ggggctaccc gttggcagtt attgtataaa gtgcagcttc
     7141 ctttggcgtt gccaaccatc ctgacaggtg tcaatcagac aataatgatg tcgctttcta
     7201 tggttgtcat tgctgccatg attgctgccg gtggtctggg agaaattgta ttgaaaggta
     7261 ttacccaaat gaaaatcgga cttgggtttg aaggtggtat cgcagttgtt attttagcta
     7321 tcatcttaga ccgtatcaca caaggaatgg caggacgaaa aaataagaac taaacggaaa
     7381 ggataaaata cgtatgagaa tatataaaat agtaggaata gtattgtcag ctatactttt
     7441 gctggcttcc tgtactaatt cagatttaga gaaaaagaaa gtaaagatag cctatgccaa
     7501 ttggctggaa ggtattgcca tgagtcattt ggctaaggtg gtattggaag aacatggata
     7561 tgaggttgaa ctgcaaaatg ctgaccttgc ccccatcttt gtatctatgt caggaaagaa
     7621 atctgatgtc tttctggatg cctggttacc aataacgatg aaagattata tggatcagta
     7681 tggagacagc atcgaatttt tgggtgaggt atatggagaa gcccgtgtag gactggttgt
     7741 tcctcaatat gttacgatcc agtctattag tgagctggaa gctaataaag accgtttctc
     7801 ttctgaaata gtgggaattg atgccggagc aggaattatg aagacgaccg ataaggccat
     7861 tgctgcttac ggacttgatg ggtataccct catgacttca agtagttcca ccatgctggc
     7921 ttctttgaaa aaagcgatgg acaaaggaga atggattgtc atcacggggt ggacaccgca
     7981 ttggatgttc gaccagtttg acttgaaatt cttggatgat ccgaagaaag tatatggaga
     8041 cttggaagaa atacatgcta ttgcatggaa aggattcagt gagaaagatc cgtttgctgc
     8101 cgaattcttt ggcaacatca aactaacgac agaagaactt agctctttta tgacagctat
     8161 gaaggatgcc cggatggatg aagaagaaat agcccgtaaa tggagggatg aacatcggca
     8221 gttggtggat agttggattc cgaagtcaga gaataaatag attggagcat tgttattttt
     8281 aattttaaat ataaaataga catgaactct agtgggaaaa agggagtatt gtttatgtta
     8341 gacagagttc atacaataaa aaaacggtaa tcttctacaa gattaccgtt ttatatttat
     8401 agggtattac tattattcag caccccagtt ttctctagcc aaacgtttgt agctgttgta
     8461 acgccattta gcgttttctt cagcagcttt gaacagttct tcagcttcag caggatattg
     8521 tttcattaca gaagcgtaac gaacttcacc cttcaagaaa ccttggaaat cttcccagtt
     8581 cggttctttg ctatccaatt ggaatgggtt cttgccttct tcttccaaag ccgggttgta
     8641 acgccacaag tgccagtaac cgcacttaac agctttttct tcttcttctt ggctcttacc
     8701 catacctgct ttcagaccgt ggttgataca tggagcataa gcgataatca aagatggtcc
     8761 cggatatgct tcagcttcac ggatagcttt cagagtttga gcttggtcag cacccatagc
     8821 gatctgtgca acatatacat aaccgtaagt agtagccatc agaccgaggt ctttcttacg
     8881 tacgcgctta ccagcagcag cgaacttagc gatagcacct accggagtag ctttagaaga
     8941 ctgaccacct gtgttagagt aaacttcagt atccagaacg aggatgttaa cgtccttacc
     9001 ggaagcgatt acatggtcaa gaccaccgta accgatatcg taagaagcac cgtcaccacc
     9061 aatgatccac tggctgcgtt ttacaagata ttgttgcagt tcagcgattt gtttgcagtg
     9121 gttacattta tccttgttag cttcaacaac cggaatgatc ttagcagcca attccttagt
     9181 cttgtccgca tccagcatat tgttgatcca ttcagcgaac agttctttta cttcagcagg
     9241 agtgcaatca gcagcaatag cctcgttcat cactttcacg agacgagcac gcatcttttc
     9301 gttagccagt tccataccca aaccgaattc acagaagtct tcgaacagtg agttagccca
     9361 agcaggaccg tgtccgtttt cgtttgtagt atacggagta gaaggaacag aaccagagta
     9421 gatagaagaa catccggtag cgttagcaac catttcacgg tcaccgaaca attgagaaat
     9481 caatttcacg tatggagttt caccacaacc agagcaagcg ccggagaact caaacaacgg
     9541 agtagcgaac tgtgagttct tcacgttagc cttgatatca acaagatgtt gtttagtctt
     9601 cacgttttca gcacagtaag tccagttttc agcttgagcc aattggcttt cgaggtgttt
     9661 cattgtcaat gctttgccac ccttcttcgg attacccgga cagatgtcgg cacagttacc
     9721 gcaacccaga cagtcgagaa cgtccacctg gatacggaat gtcataccgt cgaatgcttt
     9781 acctacagct ttcagttgtt cgaacttagc acccttctgc tcttcagcgt cgagtacgaa
     9841 cggacggata gaagcgtgag gacaaacgta tgcacacttg ttacactgga tacagttttc
     9901 agcattccat tcaggaacga atgcagctac accacgtttt tcgtatttag cagttccttg
     9961 ataccaagta ccgtcttcga tacccttgaa tgcagatacc ggcaacaagt caccgtcttg
    10021 tgcattgatt ggacgaacta cttcgttgat gaatgcagga tcgttgtttt cagcttttgc
    10081 gtcatccgga aggttagccc aagcaggatc aacagccaaa gtcttgtatt caccaccacg
    10141 gtcaacggca gcatagttct tgttaacaac gtcttcaccc ttcttgccgt aagacttaac
    10201 gatgaatttc ttcatctgct caacagcttg ttctacagga ataacgcctg tgatacggaa
    10261 gaatgcagat tgaaggattg tgttggtacg gttacccaaa ccaatttcca gtgcaatttg
    10321 tgttgcgttg atatagtata cagaaatgtt gttctgtgcg aaatatttct taaccttgtt
    10381 aggcaggttc ttagccagtt cttcaccttc ccagattgtg ttcagcagga aagaaccgtt
    10441 cttacgcaaa ccacgagtta catcgtacat gtgcaggtaa gcctgaacgt gacaagcaac
    10501 gaagttcgga gtgtttacca aataagtaga acggatcgga ttatcaccga aacgcaagtg
    10561 agaacaagtg aaaccacccg acttcttaga gtcataagag aagtaagcct ggcagtgttt
    10621 gtcagtgttg tcaccgataa tctttacaga gttcttgtta gcacctactg taccgtcagc
    10681 acccaaaccg tagaatttag cttcgaacat accttcgccg cctaaagcga tttcttcttt
    10741 ttgaggaaga gaagtgaaag taacgtcgtc tacgataccg atagtgaagt ggttcttcgg
    10801 cattggcata gccaagtttt cgaatactga aagaatttga gcaggagtag tatcttttga
    10861 acccaaaccg tagcgaccgc caacgataac cggagcattt tctgcaccgt agaagcagtc
    10921 tttaacgtca aggtaaagag gttcaccgtt agcacccggt tctttagtac ggtcaagaac
    10981 tgcgatagtc ttagcagtct taggtacagc agccaagaag tgtttagcag agaacggacg
    11041 atacaggtgt acggcaacca tacccacttt ttcgccgttt gctaccaggt agtcgatagc
    11101 ttcgcgggca gcttctgtta cagaacccat agcgataatt acgcgttctg catcttctgc
    11161 accatagtaa tcgaacaaac cgtatttacg acctgtgatc ttagaaattt cattcatgta
    11221 ttcttctacg atagcaggaa ctgcttcata gtagttgttg catgattcac gatgttggaa
    11281 gaaatggtca ggattttcag ccataccacg agctaccggt ttcatcgggt tcagtgcgcg
    11341 ggcacggaat tcagccaaag cttcctggtc gatcagcgga gcaagatcat cattttccaa
    11401 catttcaatc ttttggattt cgtgagatgt acggaaacca tcgaagaagt tcatgaacgg
    11461 aacgcgagat ttgatggtag ccaagtgagc aacaccagcc aaatccataa cttcctgtac
    11521 agagccttca gccaacatag caaagccagt ctgacgagct gacattacgt cttggtggtc
    11581 accgaagata cacaatgcgt gagaagccaa tgtacgagca gatacatgga atacgcaagg
    11641 caagaactca ccggcaattt tgtacatgtt agggatcatc aggagaagac cctgggaagc
    11701 agtgtaagta gtagtcaacg caccagcctg aagagaaccg tgaactgcac cggcagcacc
    11761 accttcagat tgcatttcct gtactaatac tgtttcgccg aagatgttct tacgtcctgc
    11821 ggcagcccat tcgtctacgt actcagccat agtcgaagaa ggagtgatgg ggtagatagc
    11881 tgctacttca gagaacatat acgagatatg cgctgcagcc tggttaccat cacaagtgat
    11941 gaatttcttc tgtttagtca taactaaatt aaatatttaa gtaaataaat cttttaatat
    12001 aaaaagccga acatccagag aggtatctgg ttgccccgac ctatttcagc cttatgcaac
    12061 gcgtatgtta cattcggatt gttcttgatc tttgcgcctt cctggcaaat tttgaacggc
    12121 attacttcgt ctaccataaa agagacgttt ttatctcctt tatgtacctt atggtctttc
    12181 cataaagaat ttgcaaagaa tgtgtcgagc acatcctgct cttccacttt caccggatag
    12241 atggaataca tcaggttgga gttgtgcatc attatctttg aaggtttttt agggaattct
    12301 tcccctttcg gataaaccag attaatgagt cgcgcatctg ccagatactt gatatagttc
    12361 atcaccgtgg cgcgagatgt ctgtatgtcg cttgccagtt ggctcacatt tggagccttc
    12421 ggcccgtcga cagcgagcaa atatagtaat ttttttatct ttgaaagata tttcagttca
    12481 atttgtttga tgagaagtat atctacttcc accatcatgt tcatcgtttt cagcagattc
    12541 tccgaaaagt tacgcttttc gaggaagaac ggatagaagc cgtggtgcag gtaatcctgg
    12601 aaataatcca acggacgaac tttggagagt actcctttgg caatctgttc gtgagtgcta
    12661 agaatttctt cgaggctata tgccctgaat ttcatgcctg tttgcaagtt taggaattca
    12721 cggaaagaga atccacgcag gttatagctc ttggcgatat cacgtaattc aagattttct
    12781 tctttcagtc gcatcacgga cgagccggtg aagacaattt tcaggttagg aaaacggtcg
    12841 taacacatgc gtaactcttt gctccattcc ggatgtttga acacctggtc gatcaacaac
    12901 acttttccgc cacgtttttg aaattcgttg gcgaagtcta caatgctgtg gcccgagaaa
    12961 tagaagttgt tcatgttgat gaacagacag gaacggtcgt tcccgaattt ctctttggcg
    13021 tattggagaa ggaaagtggt ttttcctacg ccacgtgtcc ctttgatacc aatcaggcgg
    13081 tcgctccaat cgatctcgtc cataagatcg cggcgaacgg gggcattggt gtgctcaacg
    13141 aggtaggcgt gtgtgcggta gaatgattcc atttcagttc tttgtttttc gggtggcaaa
    13201 tatactgctt tttttaggat ttgcaaagta gagatggcaa aattgtgtgt ttaattccaa
    13261 ctttctgttt attgtagtca ttcctgacta tttcctgtat atatttgcag aataaagttt
    13321 tgaattcatt tgaaatgaca aaaaaggctc tttatatatt caatccggaa catgacttgg
    13381 cgttggctag cggtgaaaca aattatatgg ctccggcttc tgccagacgt atggcttccg
    13441 agttggcttt gcttccgatg tggtatgcag aggaggggag tgctgtatta gctccttccg
    13501 cttataatct cggctatgtg aagaagatac aggaattatt aggactttcg gttgatttga
    13561 tgacagagcc ggaacttgct attgaaccga atttggatat tcgtccttgg ggatgggatg
    13621 tagctttgcg gaaacggctt tcagggctgg gcatggatga agccctgctt ccttctatgg
    13681 agcaattaga cggtttgcgg gaatactccc atcgttctaa agccgtctca ttgcttccgg
    13741 aattacaact gaatgaatat ttctgcggag aatcttatta tttgaagaca caagaagaat
    13801 ggaaaacctt tgtggaagaa cgggaatgct gcctgttgaa agctccgctt tcgggaagcg
    13861 gtaaaggctt gaactggtgt aaaggcatat ttactccttt tatatccggt tggtgtacgc
    13921 gtgtggctgc ttcgcagggt ggaatcattg cggaacctat atataataag gtagaagact
    13981 ttgccatgga gttttattcc gatggtacag gtgaagtgac atttatggga tattccctct
    14041 tctataccgg aaagagtgga atgtatgaag ggaatcgttt gctttctaat gaggcaatct
    14101 ggaaacaact ttcgcaatat gtcccttcaa aggttctgac ggatttggag aactgtttga
    14161 aatatagact ttctgcgttg gtaggaaccg tttataaagg ttatcttggg gttgatatga
    14221 tgatttgtcg gtttccggaa aatgaaaagc cggtttttcg gattcatccc tgtgtggaaa
    14281 ttaatctgcg catgaatatg ggagttgttg cgcgtttttt atatgaccgt tatgtacgtt
    14341 ctggttcaac agggcgtttt gtgattgatt atcatccttc ggaaggtgaa gccttgcagg
    14401 aacatgaacg aatgtccgca acttatccgt tggaaatcag ggaaggtaga gtgtactccg
    14461 gttatttacc tttggttcct gttcatagga gaagttgcta tcgcgcatgg atatgggtaa
    14521 ctcctgataa tatttaactt tatctgttca caccagccag cgactgatat tgcgtttttc
    14581 cgcactgaac tccaccccga tctttatcac ttcacgtccg tctgcctgat acggtatcag
    14641 atagccttta tcgtcgatct gcttcaatgc cgcttctgct gtgtcatgca gcttgaattc
    14701 gaagacatag atatatttag gtgttttcac tacggcatct gcacgaccgc gggcgctgcg
    14761 tacttcggca tcggtgaact gtcccataag tttgaagaca atatagaaaa ctacttggta
    14821 gtgacgctct gtctgctcgt tcaattcgta ggtgaaatcg gcaaagaagg cttgcaggcg
    14881 ggtaagaaag gcatcgtagt ctcccgaacg aagttcttgt acaaacttgc cgatgtaaaa
    14941 tccttggtca ctgtttctca ctccggtgta aaatggaacc aggaaattaa tgaagccgta
    15001 gcggacttca tcattaggaa attgcaatag atagttacca aattccctat cgaaatcttt
    15061 tatcgtcaga tagccacttt ggtaaatcaa cggaatcggg ttattggaat ctacacgata
    15121 ttcggagaac atggaagacg gtgcttcgat cccgtcaagc aaagtacgca ggtcgtattc
    15181 ggtttcttgc agcatctcga cgaggaaagt cggtgtgccg gtctggaacc agtaattgtc
    15241 gaacactttt gatttcagga cattcagtac actgaacggg ttgaagatac ctactgaatt
    15301 aatgcaaaaa tgatagccat cgtagagacg tgtcattcgt tgtaccgcgt catcataaga
    15361 aatggaatta ttggctgcaa gtatcttgat ttccggttgg aaggtatcca ataattcttg
    15421 aagagtgatg ccgcaaaggg ttccgtaatc gggccataaa gtgatgtcct gcaactggtt
    15481 gaggtcactg aatacactta cttgtgagaa tttcgtcact cctgtgagga agacgaaacg
    15541 caggtagcgg tcggcacttt tcaatactcc gtaaaaggct ttcagggttt tacggtattc
    15601 atccagtaag acatcattac ctaaagcttg caacagaggt ttgtcgtatt cgtctaccag
    15661 gactacgacg ctgctaccgg tttgttcgta ggcacgacgg atgacaccgg agaaacgacc
    15721 ggaaagagtg ttctcgtcta ttcctttgcc atattggatt tcccataagg tgagttgacg
    15781 gctgaggata tcataaagtc tttccggaga atcgtacttc tcggcattta aatccagatg
    15841 cagcacagga tgcttttccc atttcgtttc cagtttttca atggcaagcc cttcgaagag
    15901 ttctttcttt ccttcaaagt aggcttcaaa ggtagagaga agaagacttt taccaaaacg
    15961 gcgtggacga ctcaggaagt atggagtaga tgtataagct attttccata caagctctgt
    16021 tttatctaca tatagataat cgcccttacg aagtttctca aaggtctgta tcccgatagg
    16081 gagtttacga agcaggtcat tcattgttat tttcctttta gtggttcaaa gataatcatt
    16141 attttcgtaa tatttcgttt tcaatatctc aaagaacggg cgttataatt ttgtttaact
    16201 ggaaaattat catttagctc attcttgcac ggttttcacc acagaggaca cggaggacac
    16261 agaggtgaat ttgttttatg acttacg
//
