LOCUS       gnlProkkaOOCKGAHD_30   10560 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OOCKGAHD_30.
ACCESSION   gnlProkkaOOCKGAHD_30
VERSION     gnlProkkaOOCKGAHD_30
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 14:22:36
            Original ID  :: gnl|Prokka|OOCKGAHD_30
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10560
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10560
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1246:5560]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1247..5560
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10560
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10560
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             35..1183
                     /locus_tag="ctg30_1"
                     /transl_table=11
                     /translation="MSEQRQDKNLLSEPHKTESDEIEIDLVDIFRKIIAIRKKLYKAVG
                     IGFIIGIIVAVSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             1247..1966
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.7e-17, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             1987..3288
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 209;
                     E-value: 1.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_3"
                     /sec_met_domain="CTP_transf_like (E-value: 2e-13, bitscore:
                     40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 8.4e-122, bitscore:
                     395.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1e-63, bitscore:
                     204.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             3305..4429
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.1e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.4e-21, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4439..5560
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg30_5_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_5"
                     /sec_met_domain="Aminotran_5 (E-value: 1.5e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4529..5536
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg30_5_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg30_5_Aminotran_5.1"
                     /locus_tag="ctg30_5"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5557..6030
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 73.7;
                     E-value: 2.7e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_6"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYSNIY
                     LGKNAEIRSGCYLIARDKIIIGENSTLAYGTTILTTADPNGPYNALAVLYPYKKAPVVI
                     GDNVWIGANVTILPGVTIGDYVVVAAGAVVTKDVPSGVLVAGVPAIVKKRFNK"
     CDS             6027..7472
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_7"
                     /sec_met_domain="Polysacc_synt (E-value: 8.4e-33, bitscore:
                     103.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKTSLKNKAICGIFWSAVERFLSQGIQFVVTVIMARFLLPSDY
                     GMVGMLAIVLQLSQTLMDSGFTNALIRYKERTEIDYSTVFFFNILASLVIYFLIFFLAP
                     YISWFYKIGQLVEITRILSIVIVLNSFAIIPKTKLIIAVDFKTQSKVSFIAALVSGIIG
                     IWAAYLDFGVWALVGQTLVNGLLIVVLYAYFCRWKPLWIFSLKSFRLLFAFGSKLVLAN
                     ILNTLYKNLYAIVIGKKFSSVDLGFYTRAEQFAQFPSYNLSAIISRVTYPILSLVQNDN
                     DRLSALYRKYVRLSSAFIFPLMILLIVIAQPLVLLLLTEKWIGVVVLLQILCLDWMFDH
                     LSSINLNLLYVKGRSDLALRLEVIKKVLATGILLLSIPWGIVGMCWGRVMYSLIAVYLN
                     TYYTESLIKLSLIRQMRDILPSFFLALIMGGGTWYMILLLEGEIVQIVVGSVIALLLYG
                     TLLYCFSRSLFDEIWAVILKIKR"
     CDS             7472..8194
                     /locus_tag="ctg30_8"
                     /transl_table=11
                     /translation="MDKLSLIISKIRRNHWYRTYMRPIYLFVYGNRKLKNRNRIFLQYS
                     QELLTNFHQAMNEVGIPYWLEFGTLLGAVREHSFISHDFDLDVGLFKEDYSDIIREVLK
                     KYGFKRIRCITALDFIDAYEETYLYKGVTIDLFLFSREKNCDGVYCYDFVPVYSDIKRT
                     KKGDNAIRRIHFPRIDLIEYSFIGINTFVPENYEEHLCMHYGKDYMIPNPHWKDSDAQH
                     TDIFYGREIRIELFDKSK"
     CDS             8208..9221
                     /locus_tag="ctg30_9"
                     /transl_table=11
                     /translation="MFYLFFLLIVLFLLYIQSRKRQYSTVAGICVPIIIIFVVICRYRV
                     GYDYLTYYTLIENEEEAQILYLFSPLSIVWAEIALYFESPQMLFVLFGLPTFALLIFTL
                     KKYSKDYALSVTILICFFFFTSLSIIRQALALAICFYGYRFIVKRSLIKYILCILIAAL
                     FHPSAGVAIIIYWLPFLKFRLVVLLSIISIVAKPLFFYMLNILGVYTSYLDGKMDIEGG
                     KYTQLIYFLLFIICFVLGSKNIDKNKCNLFNVLLLSFVFVSFLGAHLGGRIAFYFNIYY
                     CLLIPKVVKGLDGQLREQVKLLSYFLCISYFLLYLFVPFIKGVPSYYIPYKFIFFK"
     CDS             9226..10185
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 57.2; E-value: 3.2e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_10"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1e-42, bitscore:
                     135.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLISIIVPCYNSERYLSDCLLSILNQTYVNWEVICIDDGSQDNTL
                     SILNHYATLDERFKIISQSNAGVSVARNKALSQCQGEYICFVDSDDLIEPNFLITLLQL
                     ISHQADLAICGFTRSMVFCMDDAQGYIEMSGKRCIERIILDKSFNPQICCMLFRHNIIK
                     EKQLEFVIGCTRGEDREFILKYLVYSNKVCYTNNLLYHYRVNDQSAMAIFSIKSLTSIE
                     ASQRTVNYYKKVNYSVRGLEFEFSRTLWKFMILAILSGQNDLYQIIREKYDLKRQMEHL
                     YSHPGLSEKLTARLFVWNEALFKWVFSIIRYLYKKRWR"
ORIGIN
        1 ctaatcttat aaagaaataa tagaatttac ttttatgtca gaacaacgac aggataaaaa
       61 cttgctctct gaaccacaca agacagaaag tgatgagata gaaattgatt tggtcgatat
      121 ctttcgcaag attattgcta ttcgtaaaaa attatacaaa gccgttggaa ttggttttat
      181 tattggaata attgtagcgg taagtatccc taaacagtat acagtaaagg ttaccctttc
      241 tcctgaaatg ggtaatgcga aggggagtaa tggtttagcc ggacttgctg cctcgttttt
      301 aggagatggg gctctaatag gggaaagcac agatgccttg aacgcttctc tttcagcaga
      361 tattgtttct tcaactcctt ttttattgga acttttagaa atggaagtct ccgtttctaa
      421 aaaggatgat aaaatgactt tggggtctta tctcgatgaa gagtcatctc cttggtggga
      481 ttatcttata ggttttccgg gcatagtaat aggaggagtt aaatcattat tcggagaaga
      541 tacggttcct gccagtggag ggcggcaagg aactatcgaa ttgacgaaag aagtaaatga
      601 gaagattaat tttcttaaaa agaagattag tgcatccatt gataagaaaa ccgccataac
      661 gagcattacg gtcaccttac aaaatccgca gatcactgcg gttatagcag attctgtcgt
      721 tcataaatta caggaatata ttattgggta tcgaacttca aaagtaaaag aagactgtgc
      781 gtatttggaa cggttgttta aagaacgtca gcaggaatat tatgctgctc aaagaaaata
      841 tgcggattat gtagacgccc atgataatgt ggttcttcaa agtgtacgtg ctgagcagga
      901 gcgtttacag aacgacatga gtttggctta tcagatatat agtcaggttg ctaatcagtt
      961 gcaggtatcc agagccaaag tacaggagga aaagccagtc tttgcagtag ttgagcctgc
     1021 cgttgtacct ttgaaacctt caggtatggg actcaaaatt tatattttat tatttgtgtt
     1081 cctgtccgta tctggtactc tcgtgtgggt gctttttggc aaaagtctgc tggctagctt
     1141 gagaaaagaa ctgaaaaata aggagataga acaggataaa tgatgctaaa acgtcgttta
     1201 caacattctt atatcaatta aattcactta ctatattatt aaacgaatga tacgtacagc
     1261 tatgataatg gctgcgggca tgggaacccg ttttggccaa tatacagaat tgatacctaa
     1321 agggttcgtc aaagtgggag gtattccaat gatagttcgt tctattgata ctttgttatc
     1381 atgtggcatt gagcgaattg taatcggtac aggatataaa caagaagtgt atgaagaatt
     1441 gaagacagac tatcctatgc ttgaaacctg ttttagtcct cgttatgctg aaacaaatag
     1501 tatgtatact ttatataata cgcgggagat tctgggcaat gatgattttt tattgttaga
     1561 gtcagatttg atttttgaga aacaagcaat aatgagctta ttggagtgtc ctgcggcaga
     1621 tgcaatgcta atagctccag tgacaaagtt tcaagatcag tattatgtgg aacatgatga
     1681 taattttcgc ctttcttcat gttctgtcaa taagaataaa ctaaacgcta aaggcgaatt
     1741 ggtcggcatc cataaactat ccggttcctt ttacaaaata atgtgtgctg attatgcgag
     1801 tattgttgat gaacaaccca atttgggata tgagtatgaa ttactacgaa tatcttgttc
     1861 tcaatctcct gtttatgtgc ataaagtaga agggctgaaa tggtatgaaa tcgatgacat
     1921 atcagatttg gaatatgcag agaaatatat tgttccgtat tgttaattaa aataatatat
     1981 caaattatga gtaagacagt ttatattggg atgactgcgg atattatgca tccaggactt
     2041 atccgcatta ttaatgaggc tactaaatac ggtgatgtta taattggtct tcttacagat
     2101 aaagctattg cggagcataa acgccttcct tatctgacct atgaacaacg aaaagaggta
     2161 gttcagaata ttaaaggcgt atgtaaagtt gttcctcaag aagaatggag ctatgttgag
     2221 aatctcaaac gcattaaacc tgactatata attcatggtg acgactggaa aaccgggcct
     2281 ttacgtgaag aacgtgtgcg cgtatttgaa gtgatgaatg aacagggagg aaaggttatc
     2341 gaaattccat atactttggg aattaattca tcttctttgg ataaagatat taaggctata
     2401 ggtacaaccc ccgatgtacg tttaaaatca cttcgtcgtt tgataaatgc caaacccgta
     2461 gttcgtattt tggaagctca tgatggacta tgtggcttga taattgaaaa tcaggaaata
     2521 ttaaaagggg ataagaggga agtatttgac ggaatgtggt ctagtagcct tacggattca
     2581 accagtaaag gtaaacctga tattgaggcg gttgatttaa ctacccgatt gcaagatttg
     2641 aataatattc tggagtgtac tactaaacct attatttttg atggagatac aggtggtaaa
     2701 attgaacatt tcgtatttac agtacgcact ttagaacgtc atggaatctc agctataata
     2761 attgaagata aagttggatt aaaaaagaat tcattgtttg gtacggatgt tattcaaact
     2821 caagatacaa tcgaaggttt ctgtaataag atcaaagcag gaaaggcatc tcagattact
     2881 gatgatttta tgattatcgc tcgtattgag agccttatag cgggaaagcc ggtaagtgat
     2941 gctttagaga gagcttttgc atatgtccaa gcgggagcgg acggtattat gatacatagc
     3001 aaaaataagt cgggtgaaga tataaaagaa ttttgtttgg cgtttcgaaa acagtatgct
     3061 catgtaccta tcgtggttgt gcctactaca tatgatcata tttatgagtc tgaattgtgt
     3121 gattggggtg tgaatataat tatttatgct aatcatatgc ttcgtgccgc ttatcctgct
     3181 atgatgaatg tcgcaaagac aatattagag aatgaacgtg ctttagaggt gcgcgaactg
     3241 tgtatgccca taaaggaaat attggaactg attccgggta ctaaataaaa agaggaatat
     3301 cattatgtta agcgtagaaa aagtttatga aacgtttctg agtcatgacg ttgatttttt
     3361 tacaggagtt ccagactcat tactaaaaaa tatttgtgcc tatatcacag accatacttc
     3421 acgtgagaaa catatcatag ctgctaatga aggtgcggct gtaggaattg cttcaggtta
     3481 ttatatggca tcaggtaagg ttcctgtggt ttatatgcaa aattccggct tgggtaatac
     3541 tgttaatcct ctgctgtctc ttgcagatga acaagtatac agttttccaa tgcttttgat
     3601 gattggctgg cgtggtgaac cgggaacaaa agatgaacct cagcataaaa aacagggtga
     3661 ggtaacttta gatttgttga aagcaatgcg gattccttat ataattcttg attcaaatga
     3721 gaatgatgca tttattcagc tccatgatat catacaatca gcaaaaacta agaatattcc
     3781 tcatgcaata attattcgga aagatgtttt tggcaaatat aaacttcaaa aagaattcgg
     3841 atgtaattat cctttatctc gtgaggatgc tttgcaaata gttgtggatt atctgcctga
     3901 aaattcagtg gtcgtttcta ctactggcaa gctttctcgt gagttatttg aatatcgaga
     3961 aatgaaagag caaggtcatg aacatgattt tctcacggta ggctctatgg gacatagttc
     4021 atcaatctct ttgggtattg ctatagcaaa gcaagataga cctgtttatt gcttggatgg
     4081 tgatggagca tttattatgc atttaggggc aattagtaac attggcgatt tatctcctaa
     4141 aaactattat catattttgt ttaacaatgg tgctcacgag tctgtaggag gacagcctac
     4201 tttaggattt agtttagata ttccggctat tgtccggggg agcggatata agcatactta
     4261 tactgtttgt acaaaagttg aaattgaaga agcaatgaag cagcttccaa agttatgtgg
     4321 tcctgttttg ttggaaataa aggttaaaat agattctcgg gagaatttgg gacgtcccac
     4381 gactactcct atagagaata aggagcattt tatggatttt ttaaaataaa tatattcgat
     4441 gaaaatagaa agaaaaatat tattaaatcc tgggcctgcc actactactg acagtgtaaa
     4501 aatggcacaa gttgttccgg atatttgtcc tcgcgagaaa gaattcgcag gtatgatgaa
     4561 acaacttcgg gacgatttgg tcagagttgc tcatgggaat ttggaaaaac ataccgctgt
     4621 attattttgt ggctcaggaa ccatcaatat tgatatatgt ctaaattctc ttcttcctga
     4681 agacaaaagg gtgcttatag tgaataatgg ggcatatagt acccgtgctg tagaagtgtg
     4741 tcaatattat ggtttgcctc atattaattt ggaattttcc gtttacgaac gtcctgattt
     4801 atcggtggtg gaaaatgtgt tgcaagaaaa ccctgatata gctatggttt atactactca
     4861 tcacgagacg ggtacaggaa ttctgaaccc tattcgcgag atgggcgcta tagctcataa
     4921 atatcaggct aaatttgtcg tcgatactac ttcttctttg ggcatgattc cttttgatat
     4981 agagaaagat aatgtggatt tttgtatggc atctgctcaa aaaggacttc aagcgatgac
     5041 aggtctttct tttattatag gcaatgagga acagattaag ttttcaaaaa aatatcccaa
     5101 gcgttcttac tattgtaatc tttatttgca gtatgagaat tttgagagaa caggtgaaat
     5161 gcattttact ccaccggtac aaactattta cgccactcgt caggcattaa atgaatattt
     5221 tgaagtgggc gaagaagcta agtttgcccg tcacaaaaga gtttttgagg ctattcattc
     5281 aggtataaat gaaattggtc ttaaaagtgt aataaagcgt gaatggcagt caggactggt
     5341 tgtctcagtt caatacccag aagatcccaa ctgggatttt gagaaaatac atgattattg
     5401 ttatgagcgt ggatttacga tttatccagg taagatatca actgaggata cttttagaat
     5461 ctgtgcttta ggagagatag aagtagatga tattgagaac ttctttaaag tactaaaagc
     5521 tgcattaaat cattataacg tcacattacc gatgtcatga ttgcagaaat attattgaag
     5581 attcgtcatt tttatttttc ccttcgtggt atacacttcc atccggaaag tgttatttct
     5641 ggagtgccta ttcgtagctt tcgcttagta ggcaaatata gcaatatcta cttaggtaaa
     5701 aatgctgaaa tacgttcagg ctgttatctg attgctcgtg ataaaatcat tattggagaa
     5761 aactcaacac tcgcctatgg aacgactata ttgacaactg ctgatcctaa tggaccgtat
     5821 aatgcattag cagttcttta tccttataaa aaggcaccgg tagttatagg agataatgtt
     5881 tggattgggg ctaatgttac catccttcct ggagtaacta ttggtgatta cgttgtagta
     5941 gcagctggag ctgttgtaac aaaagatgta ccttcaggag tattggtagc tggtgtacca
     6001 gctattgtga aaaaacgttt taataaatga aagaaaaaac ttctttaaag aacaaagcca
     6061 tatgtggaat cttttggagt gcagttgaac gatttttatc acaggggata cagtttgtag
     6121 ttacagtcat tatggcgcgt tttctattgc catctgatta tggaatggta ggaatgttag
     6181 caatagttct tcaattatct caaacgttaa tggatagtgg ttttactaat gcccttattc
     6241 gttataagga acgtactgaa attgattatt caacagtttt cttttttaat atattagcat
     6301 cattagttat ttattttcta attttttttc tagctcctta tatatcgtgg ttttataaaa
     6361 taggtcaatt agttgagatt actagaattt tatctattgt tattgtttta aattcctttg
     6421 cgattattcc taaaactaaa ttaataatag ctgtagattt taaaactcaa tcaaaagtct
     6481 catttattgc agctttggtt tcaggtatta ttggcatttg ggctgcatat ttagattttg
     6541 gagtttgggc tttagttgga caaactttag taaacggatt gttgattgta gttttgtatg
     6601 catatttttg tagatggaaa ccattgtgga tattttcatt gaaatcgttt cgtttattat
     6661 ttgcttttgg gtcaaaatta gtattagcta atattcttaa tactttatat aaaaatctgt
     6721 atgctatagt tataggaaag aagttttcgt cggttgattt aggattttat actcgtgcgg
     6781 aacaatttgc tcagtttcct tcatataatt tgagtgcaat aatttctaga gtgacatacc
     6841 ccatattgag ccttgtgcaa aatgataatg atagattatc tgctttatat aggaaatatg
     6901 tccgtttatc ttctgctttt atctttccat tgatgatttt gttaattgtc atagctcagc
     6961 cactggtatt attgcttttg acagaaaaat ggataggagt agttgtattg cttcaaatat
     7021 tgtgtttaga ttggatgttt gatcatttga gtagtataaa tttgaattta ctatatgtaa
     7081 agggacgttc agacttggct ttacgtttag aagttataaa aaaagtgtta gcgacgggga
     7141 tccttcttct atctattcct tgggggattg taggtatgtg ttgggggcgt gttatgtatt
     7201 cattgattgc tgtgtatttg aatacttatt atacagaatc attgattaaa ttaagtctta
     7261 ttagacagat gagagatata ctaccaagct tttttttagc attaataatg ggaggaggta
     7321 cttggtatat gattttattg ttagagggtg aaattgttca aattgtagta ggaagtgtta
     7381 ttgctttatt gctatatgga acgttgttgt attgcttttc tcgatccttg tttgatgaaa
     7441 tatgggcggt tatattaaaa ataaaaaggt aatggataaa ctgagtttga ttattagtaa
     7501 aatacgacgg aatcattggt atagaaccta tatgcgtcct atatatttat ttgtttatgg
     7561 caatagaaaa ttgaagaata gaaatagaat atttttgcag tattcacaag agctgctaac
     7621 taactttcat caagcaatga atgaagtggg aattccttat tggttagaat ttggaactct
     7681 tttaggtgct gttagagaac acagttttat aagtcatgat tttgatcttg atgtgggcct
     7741 ttttaaggaa gattattcag atataataag agaggtctta aaaaaatatg gtttcaaaag
     7801 aataaggtgt ataaccgccc ttgattttat tgatgcttat gaggaaactt atctttataa
     7861 aggtgtgaca attgatcttt tccttttttc aagagagaaa aattgtgatg gggtctattg
     7921 ttatgatttt gttccagtat attcagatat aaagagaact aaaaaaggtg ataatgcaat
     7981 ccggagaatt cattttccta gaattgattt gattgaatat tcatttattg gaattaatac
     8041 ttttgttcct gaaaattatg aggaacatct ttgtatgcat tatggtaaag actatatgat
     8101 tccaaatcct cattggaaag attcagatgc gcaacatact gatatctttt atggtagaga
     8161 gattagaatt gaattgtttg ataaaagtaa ataatagtag ataatacatg ttctatctat
     8221 tttttttact aattgtgcta tttttgttat atatacaaag taggaaaaga caatattcta
     8281 ctgtagcggg aatttgtgtt cctattatta taatttttgt tgtaatttgt cgttatagag
     8341 tggggtatga ctatttaacg tattatacat taattgaaaa tgaagaagag gcacagattt
     8401 tatacttatt ttctccttta agcattgttt gggcagagat tgctttatat tttgaatctc
     8461 cacagatgtt atttgttctt tttgggcttc caacatttgc tcttctaata tttactttaa
     8521 aaaaatattc aaaagattat gcgttatcag taactatttt aatttgtttc ttctttttta
     8581 catcactcag tattattcga caagctttgg ctttggctat ttgtttttat ggttatcgtt
     8641 ttatagtaaa acgttcacta attaaatata tattatgtat attgattgca gctttattcc
     8701 atccttctgc aggagtagcg attattatat attggttgcc atttctaaag tttagattag
     8761 ttgtattatt atctataata tcaatagtag ccaaaccttt atttttttat atgctaaata
     8821 tattaggggt gtatacctct tatcttgatg gcaagatgga tattgaaggt gggaaatata
     8881 ctcaattaat atactttttg ttgtttatta tttgttttgt tttgggaagt aaaaacatag
     8941 ataaaaacaa gtgtaattta tttaatgttt tattgttaag ttttgttttc gtatcttttt
     9001 taggagctca tttaggcggg agaatagcgt tttattttaa tatatattat tgtttgttga
     9061 ttcctaaagt ggttaaagga ttggatgggc aactaagaga gcaagtgaag cttctttctt
     9121 attttctatg tatttcttat ttcttattgt acctattcgt tccattcata aaaggtgtac
     9181 cctcatatta tatcccatat aagtttatat ttttcaaata gtaaaatgtt gatatctata
     9241 attgtccctt gttataattc tgaaagatat ttgtctgatt gtttattgtc tatattgaat
     9301 caaacctatg ttaattggga ggtgatttgt atagatgatg gaagtcaaga taatacatta
     9361 tctattttaa atcattacgc tacattggat gagcgtttta aaattatttc tcagtctaat
     9421 gcaggagtgt ctgtcgcaag aaataaggct ctatcccagt gtcaaggaga gtatatttgc
     9481 tttgttgata gtgatgacct gatagaacct aattttttga taacactttt acagcttata
     9541 agtcatcagg ctgatttggc aatctgtggt tttactcgtt ctatggtttt ctgtatggat
     9601 gatgctcaag gatatataga aatgagtggt aaacgttgta tagaaagaat tattctagat
     9661 aaaagtttca atcctcagat ttgttgtatg ttatttcgac ataatattat aaaagagaaa
     9721 caattagaat ttgtgatagg gtgtactcgt ggtgaagatc gtgaatttat attgaaatat
     9781 ttagtttatt ctaataaggt ttgttataca aacaatcttc tttatcacta tcgtgtaaat
     9841 gatcagtcag ccatggcaat cttttctatt aaaagtttga caagtataga agcttcacaa
     9901 cgcacggtca actactataa aaaagtgaat tattctgtta gagggcttga atttgaattt
     9961 tcacgtacat tgtggaaatt catgatttta gctattttgt ctgggcaaaa tgatttatat
    10021 caaatcattc gagaaaagta tgatctaaaa agacaaatgg aacatcttta ttctcatcca
    10081 ggactatccg aaaaacttac agcgagattg tttgtttgga atgaggcact ttttaaatgg
    10141 gtattttcta ttattagata tctatataaa aaaagatgga gatgaataaa cgaaatagat
    10201 tatctgaaca agaaataaaa aaagtagaac ttgacgcttt attgtatatt cggaaaattt
    10261 gtcagcaata tcatcttcgc tattatttag cttggggtac tttgttggga gccgttaggc
    10321 ataaaggatt tattccttgg gatgatgata ttgatataat gatgccacgt tcagattatg
    10381 agcgattatt ggagttagtt ccttccttga gacatagtta ttataaaatc ttaagtaatc
    10441 caaagaatga ggattattat tatactcatg caaaaatgat agatactcgt actttgtgtg
    10501 tggaaaatga tttgcaaact attcaaaata tggggatttg ggttgatatt ttccccttag
//
