LOCUS       c00014_gnlPro..        16310 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KPEAFPPP_14.
ACCESSION   c00014_gnlPro..
VERSION     c00014_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 15:44:11
            Original ID  :: gnl|Prokka|KPEAFPPP_14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16310
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..135
                     /locus_tag="ctg14_1"
                     /transl_table=11
                     /translation="KGKFRLCIDGIPILDWFRKKFQEIKEKLGLNTPVENKQRKGLKI"
     protocluster    1..16310
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1546:6310]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1547..6310
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16310
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16310
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(269..733)
                     /locus_tag="ctg14_2"
                     /transl_table=11
                     /translation="MERWSLVLKIVLLTTGLMFLLRTFMLQSLQDQIASLLFGAILVSI
                     YIYMLIVIPSFICLEKDQLVIKRVFGKKCIPYSCIKNAFVYDGVQNDIRYFGSNGFLGY
                     IGVMGSTHYGKYYSYVKNPNQQIFILTEKKNYLLSCENRDMFIKDLLIHL"
     CDS             complement(766..1557)
                     /locus_tag="ctg14_3"
                     /transl_table=11
                     /translation="MKSKILTLGVGAAIAATSFSSCDNSNDFPNLAIASEENLVDDETT
                     AISMKKLSQEEQVYIHDMSLLSHNILNDTNAAEAFLNAPLEYARSLGIKSSIDTDDGTV
                     RFLLAICKPEFREAVIKRDIRRFVELCEKYDIFKNANSSNIKLLNHTAITRSKDCVDVQ
                     MGFFWIGEWILLGVAYVGAGIDYAALGGPVVCASRTINSEMALQVWDVETQDGSVYELA
                     DEYKNHYVQDLVKLVKEKRPEVMERYTDKELIEIIQKTLAI"
     CDS             complement(1547..2593)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_4"
                     /sec_met_domain="Radical_SAM (E-value: 2.4e-10, bitscore:
                     32.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELLNFISPNTLSLLTTYYCTAACKNCCFECNQERRGRMSFKQME
                     TYISECVKAFPTIRLVVFSGGECFSLKDDLYQAIYYAHKKGLITRVVTNGYWAVSYEKA
                     LGILVLLKELGLNELNLSTGDDHQKWVPFDNIVNAIRAAAKVDLPCLVNIETNPSSQFS
                     EEDFKNHEELKEYIRDNKVIFSSGIWIPFDMEDKIKRDTNYNELIKHRYVQRPIISHGC
                     NSLFESIPIDPEGNVYACCGLACRKAKFLKIGNMNTAGINKIYRRQFDDFLKVWAYVDG
                     PKFILNKIAMETGKNVEVNADMHNCEACLLLLNDPSKIEYIKNNISRYISEVVLKYNIK
                     QKKANYEK"
     CDS             3352..5580
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_5"
                     /sec_met_domain="Gly_radical (E-value: 1.6e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             5585..6310
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_6"
                     /sec_met_domain="Radical_SAM (E-value: 2.2e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(6542..7801)
                     /locus_tag="ctg14_7"
                     /transl_table=11
                     /translation="MKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYPY
                     RRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAVS
                     EPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIEK
                     KESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENFA
                     PRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVRK
                     SLPKGFSVEMGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVSA
                     GGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKVQ
                     TIRKERPCNFNLQAGLRFTY"
     CDS             complement(7856..8404)
                     /locus_tag="ctg14_8"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LLHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             8592..9344
                     /locus_tag="ctg14_9"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(9449..10447)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg14_10"
                     /sec_met_domain="LysR_substrate (E-value: 8e-47, bitscore:
                     150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.4e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             10517..10990
                     /locus_tag="ctg14_11"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(11094..12092)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_12"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1e-69, bitscore:
                     226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(12147..13415)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_13"
                     /sec_met_domain="MFS_1 (E-value: 2.8e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(13665..14678)
                     /locus_tag="ctg14_14"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTTALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFLVVLKNIEKLTNPDGYVLPVALKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTLLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(14701..15858)
                     /locus_tag="ctg14_15"
                     /transl_table=11
                     /translation="MTLKNLIMKRITIKQCLLACFVLPMILAGCNDADYQVIDNAIYLN
                     EASENGSAKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVL
                     PEQYFTYDKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSK
                     FIILLDKPLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSG
                     SSDHEVYIRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYING
                     VLDVTLQTKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPA
                     DPNLIGYWKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 aaaggaaaat tcaggctgtg cattgacgga atacccatac tcgattggtt caggaagaag
       61 tttcaggaaa ttaaagaaaa gttagggcta aacacacctg ttgaaaacaa gcaacgaaaa
      121 ggattgaaaa tataattact taatagcaga gaggaggtat taattattag tgctctaaaa
      181 aactaacggg aagaatatgt cttttattct tcccgtcaag taatatcata actatatttt
      241 ccaacagacc atattaatat tcagcatatt ataagtgaat caacaaatct tttataaaca
      301 tatctctgtt ctcacagctt aagaggtaat tctttttttc tgttaatata aaaatttgtt
      361 gattgggatt ctttacatag gaataatatt tcccataatg ggtactgccc attacaccta
      421 tataccccaa aaagccatta cttccaaaat aacggatatc attttgaaca ccgtcataaa
      481 caaaagcgtt cttaatacaa gaatatggaa tacatttctt accaaacact ctttttataa
      541 cgagttgatc cttttccaaa catataaatg aaggaatcac tatcagcatg tatatgtata
      601 tagatacaag aatggcacca aataataagc ttgcgatttg atcctgcaaa gattgtagca
      661 taaaagttct taatagaaac ataaggccag tagttaataa gacaatcttt aataccagag
      721 accaacgctc cattaccggc tgaaattttg atttatatac gctcattata ttgctaatgt
      781 cttctgtatt atttcaataa gttctttatc cgtatatcgt tccataacct caggacgttt
      841 ttcttttact aacttaacca aatcttgaac atagtgattt ttgtactcat ctgctaactc
      901 atatacactt ccgtcctgtg tttcaacgtc ccaaacctgc aatgccattt cactgttaat
      961 tgttctggaa gcacatacta cgggaccacc aagtgctgca taatcaattc ctgccccaac
     1021 atatgcaaca cctaacaaaa tccattcacc gatccaaaag aatcccattt gcacatctac
     1081 acagtcttta cttcttgtta ttgcagtatg gttcaataat ttaatattgg aagaattggc
     1141 atttttaaaa atatcatact tttcacataa ctctacaaat cttctaatat ctctctttat
     1201 tacagcctct cgaaattccg gcttacaaat tgctaataga aaacgtacag taccgtcatc
     1261 agtatctata gagcttttta ttcccaaaga ccgggcatat tccaaagggg cattcaaaaa
     1321 agcttccgct gcatttgtat catttaaaat attatgtgat aataaactca tatcgtgaat
     1381 atacacctgt tcctcctgtg ataacttttt catagaaata gcagtagttt catcatctac
     1441 aagattttct tctgacgcaa tggctaaatt aggaaaatca tttgaattat cacatgaaga
     1501 aaatgaagta gcagctatcg ctgccccaac acctaaagtt agaattttac ttttcatagt
     1561 tcgctttctt ttgtttaata ttatatttta atacaacctc agatatatat ctggatatat
     1621 tatttttaat atactctatt ttagagggat cattcaacag taatagacag gcttcacaat
     1681 tatgcatatc agcattaacc tcaacatttt tccctgtttc cattgctatt ttattcaaaa
     1741 taaatttcgg gccatcaaca taagcccata cttttaaaaa atcatcaaat tgtcttctat
     1801 atattttatt tataccggca gtattcatat tgccaatttt taaaaactta gcttttctac
     1861 aagccagtcc acaacaagca tacacattcc cttccggatc aataggaata ctctcaaata
     1921 gactgttgca cccatgggat attataggtc tctgcacata tctatgtttt attaattcat
     1981 tataatttgt atcacgttta attttatcct ccatatcaaa tggaatccat ataccagaag
     2041 aaaagataac tttattatcc cgtatatact cttttaactc ttcatgattt ttgaaatctt
     2101 cctcagaaaa ctgtgaactt ggattcgttt ctatattcac caaacaaggc aaatccactt
     2161 tagctgctgc tcttatagca tttacgatat tatcaaaggg cacccatttt tgatgatcat
     2221 cccccgtgct taaatttaat tcatttaatc ccaactcctt tagtaacacc aaaattccaa
     2281 gagccttttc ataactaaca gcccaatacc cattagtaac aacccttgtt ataagcccct
     2341 ttttatgtgc ataataaata gcttgatata aatcatcttt taaggaaaaa cattctccac
     2401 cactaaagac aaccagccta atcgtaggga aagcttttac acattccgat atataggttt
     2461 ccatttgttt aaatgacatt ctccccctac gttcttggtt acactcaaaa caacaattct
     2521 tacacgctgc cgtacaataa taagttgtca acaatgataa ggtattaggt gatataaaat
     2581 tcagtaattc catggctaat tattcactta agagtttaaa ctctttcaaa atattactta
     2641 tatggcaaat gtactttgtt tttgttacag ccaaacggtt gaatacaaaa ttttaatcta
     2701 attatacaat tttaccaatg cgaataatag tttataaaaa ctataattta ttggattaga
     2761 aaggaagtag cattcataac cctcacattc tacatttgta gaaacagatt caatcaaaac
     2821 aaaaaatata taatcattat ccttctatag acacactgca taagcaggaa atttagaata
     2881 gcccccagtt ggaataatta aatatggaac agcaagaaac aaatcttaaa taatacaaaa
     2941 cacccaattt tactttttag ggtgtaaaat tgggtgttat tcttgcaaat cactgatttt
     3001 cagtatttat tgcggagaga cagggattcg aaccccgggt acctcgcagt acaacggttt
     3061 tcaagaccgc cgcaatcgac cactctgcca cctctccaga actacggtta agtagtgctt
     3121 ttctcttaaa gcgctgcaaa ggtacgaatc attttttaac ttgcaaatta ttccgcaaaa
     3181 aaatattaga aaagtatatt tggaagtaat aaccgccctc tggcttctcc ccataaatag
     3241 gtatttttat gctattcaac ataaaatagg acccttttat atacctaaac cgaaaaaagg
     3301 ttgtaaattt gcgcgctcta aaggataact aaccactaac tgattaattt tatggaactg
     3361 aataagacct ttaaagatgg actttggagc aaagaaatca atgtaaggga tttcgttagt
     3421 aacaacatca ctccttatga aggggatgct tctttcctgc aaggacctac cgaacgcacc
     3481 aaagctgtct ggaatcactg tctcaaagct ctcgaagaag agagaaacaa taatggtatt
     3541 cgtgcactcg actacacaac tgtatctact ataacctctc accctgccgg ctacatcgat
     3601 aaagaaaacg aactgatcgt cggactacag accgatcagg tgttaaaacg tgccatcaaa
     3661 ccgtttggcg gaatcaatgt ggttatgaaa gcttgccgtg aaaacggagt ggaagtagat
     3721 gacagagtta aggatatctt cactcactat cgcaagactc ataatgatgg ggtattcgat
     3781 gtgtataccg aagaaattcg ttcgttccgt tcattgggat tccttaccgg acttcccgac
     3841 aactatgcac gcggacgtat catcggtgat tatcgccgcc tggctctcta tggtcttgac
     3901 cgtctgatag aagctaaaaa agaagatctg cataatctga caggtcctat gactgaagcc
     3961 cgcattcgtc ttcgcgaaga agtagccgag caaatcaagg ccctgaaaga gattaaagta
     4021 ttgggcgaat attatggttt ggatctgagc cgaccggcat ataccgcaca ggaagctgta
     4081 caatgggtgt atatggctta tctggctgcc gtaaaagagc aggatggtgc tgccatgtca
     4141 ctgggtaatg tatcttcatt cctcgacatc tatcttgaat atgaattaag ccagggtacg
     4201 ataaccgaaa cattcgctca ggaactgatc gaccaattcg ttatcaaact ccgtatggta
     4261 cgccacttgc gtatgcagtc gtacaacgat atttttgcgg gtgatcccac atgggtgacc
     4321 gaatctatcg gtggacgttt caatgacgga cgtaccaaag ttactaaaac ttctttccgc
     4381 ttcttgcaga cactttataa cttaggcccg tcaccggaac ctaacatgac tgtactatgg
     4441 agccctgagt tacccgaagg tttcaaagca ttctgtgcac aagtatctat cgacacttct
     4501 tccgtacaat acgaaaacga cgacctaatg cgtgaagtcc gtcaatcgga tgactacgga
     4561 atcgcttgtt gtgtttcata tcaggaaatc ggaaagcaga ttcagttctt cggcgcacgt
     4621 gccaaccttg ccaaagccct gctactggct atcaacggag gacgttgcga aaatacaggt
     4681 acagttatgg taaaagacat ccctgtattg accggtgaaa cactgaagtt cgaagaagta
     4741 atggccaact ataagaaagt attgatacaa attgcacgtg tatacaacga agcaatgaat
     4801 atcatacatt acatgcacga taagtattac tacgaaaagg cgcagatggc tttcgtggat
     4861 actgatcccc gcattaacct cgcttatggt gtagccggac tttcaatcgc catcgattca
     4921 ctgtccgcca tcaaatatgc acatgtgaaa gcccgtcgca acgacatcgg actgacggag
     4981 ggattcgata tcgaaggtgc tttcccttgt ttcggtaatg acgatgaccg tgtagaccac
     5041 ctgggtgtag acctggtata tttctttagc gaagaattaa agaaactccc cgtatataag
     5101 aatgcccgtc ctaccctctc gctgctgact atcacttcga acgtaatgta tggcaagaag
     5161 accggtgcca ctcctgacgg acgcgccaaa ggcattgcct ttgctcccgg tgccaacccc
     5221 atgcacggac gtgataaaaa tggtgcaatc gcctcactga gttctgtagc caagttgcgt
     5281 tatcgcgact cacaggatgg tatcagcaat acattctcaa tcgttcccaa atcattggga
     5341 gcaacacaag aagaccgtat cgacaatctg gtgaccatga tggacggata ttttacaaaa
     5401 ggcgcacacc acctgaacgt aaacgtgctg aaccgggaaa tgttgcagga tgcgatggaa
     5461 catcccgaaa agtatccgca actgactatc cgtgtctcag gatatgccgt taatttcgtg
     5521 aaattgagcc gcgaacatca gttggaagta atcagccgca gtttccacga aagaatgtaa
     5581 ttgaatgata aacgtacact catacgagtc aatgggaaca ttcgacgggc cgggtctccg
     5641 gctcgtcgtt ttccttcaag ggtgtaactt ccgttgcctc tattgtgcca atccggacac
     5701 aattgaagcc aaaggaggga cagcaaccga ccctgaggaa atagttcgca tggccgtcag
     5761 tcagaaagct ttcttcggta aaaagggagg tatcaccttt tccggcggag agcctacttt
     5821 tcaagcaaaa tcgcttatcc cactttttaa aagactaaag gaagcaggaa tccatatttg
     5881 ccttgatacc aatggcgggc tatggaacaa tgatgtagag gaactattgg aattgactga
     5941 tctggtttta ttagatatca aagaatttaa tccggaacat catcagtctt taaccggaag
     6001 aagcaacgag cagaccctga aaaccgcagc ctggcttgaa accaatcata aaccattctg
     6061 gttgcgatac gtattagtgc ccggctacag tgacttcgaa gacgatatcc ggcagctggg
     6121 agagcatctt ggaacgtacc agatgattca gcgtgtagaa atattgcctt accacacctt
     6181 gggtgttcac aaatatgaag caatgaacaa agaatatatg ctgaaaggag tgaaagagaa
     6241 tactccagag cagatagaaa aggctgagaa actattcagg caatatttcc agaccgtaca
     6301 agtaaattga cttatataag tgtcgaaatt cgtattcacc acagattaca cgaatttaca
     6361 caaataaaga tcattggcaa tcaatagatt aagttcattc tgcggtgaat tatgacgact
     6421 gcacttattt ataattttgt aagtcacgat ataaaagtct ccctgttctt gccttaattc
     6481 attacaatac aaggcaagaa cagggagata atgtaaccgg catatttttt gccatcctac
     6541 tttaataagt gaatcgcaat cctgcctgca agttaaagtt acaaggcctt tcttttcgga
     6601 tggtttgtac tttggagcca tcatcaaaga aatacgaaac tcccggttcc acatataggc
     6661 cgacatgatc tgtcgcattg aattgcgctc ccacggcacc ggctacagaa aattgcaaag
     6721 gcttcacatt caccttatca tccgccaact ttccataaac acacttttca accattcctc
     6781 cggcagatac atagagtgta aaatatttct tttccagaaa attccagttt ccacgtacag
     6841 gaatacctat ataatgcaat ttctgactct gcatcttggt atccccctgc cgtttgatgt
     6901 cagaagacaa caacgtataa gtcaatccca tctctacaga aaaacctttg ggaagagact
     6961 tacgtacaga cagtccgaag ctaaccggct gatgatgttc ataatccacc acggcagttg
     7021 tattggactt caggtaaggg actccttctt caaatataac ttcctgatcg gcaggaatac
     7081 tcacagctcc attcatgatc gtcatcaagt cgaccctgtt agtcatcgga cggggcgcaa
     7141 aattttcgga accatttgtc ggaagtccac ctccattacc gatacccact cccatcgacc
     7201 atttaccacc acgtttagca gaagagtctc cgataggcaa ctgatacttg tctttaccag
     7261 acggtcgccg cgcttctttc ctctttggag gctgcgccgt cgcactttct tttttctcga
     7321 ttgcagcaat tgcttcctgt tgcggctcag atctcttttc ctccgtcact gcctccggtc
     7381 gcttctctac cagggaggat acctccggaa caatcaccgg atcagtattc tttgccaaat
     7441 agcccgaaac agggttaata ctcgtcgttc ctaccggctt aactggttcg gatacagcta
     7501 cctgtacatc cggcaaggca ggttccggca atacatccgg gttgacagcc agtgaaggag
     7561 ccgttgcata acggatttca tcagctaccg gactattcag aaaatacaaa ctgacagcag
     7621 tcgttagcac caataccaca gctgccgcag caaccgccca ccggcgatac ggatatattc
     7681 gtttttcggt tacaggcatc agttcccttt ccagtcgttc ccaaccggaa gcaggcatcg
     7741 gctccgaata atcttcgagc ttatccttga atgctttaat ccatttttcg tcttctttca
     7801 tcattctatt tcatttttga aatccaaggt tcacctcagt atctgtaaat acatgtcaac
     7861 cattggtcac caaccattct ttcactttct ttgccaatac actttttgca cgaaaaagct
     7921 gtgaagcaga agatttttca ttaatcccca acatctgtgc gatttccttg tgcgacttat
     7981 cttcaaaggt gtataaattg aatacggtac gatatccggc ggggagttca ttaataaatt
     8041 gcatcagcac tttctgtggt attgcttcaa cagccgaagc atccggttct tcatacgttt
     8101 cgggaacttc atccagtgcc gtggtctggt tcatcacgtc gttctttctt aagaactgta
     8161 aagccgtatt caccattaca cgctccatcc atgctctcag agagccttca ccccgccagg
     8221 taaacttgtc gaaggagtcg aaaatcttca ggaaaccgtc gtgtagcaag tcttgtgcca
     8281 tgtccctgtc tccggcataa cgaagacaga caccaagcat gcgccctgcg tactgctcat
     8341 aaagttcttt gcgggcacga ttatctccct gcctgcaacg ttccgacagc tctaattcat
     8401 tcattctcct aaacacgtgt ttaccttata aatgcagcaa agatagaaat actgcacaga
     8461 gagaacaact cttttatcac ttttgtttct ttaacatttt aggatgcaat atttcatcac
     8521 ttcctgcatt ttctcaatac aataaagaat aaatctcaat ggataaatag gataaaacca
     8581 acaagaaact tatgaagaaa tttaatttaa taacttttgc cgtcatcctg atgttattgc
     8641 ccattttaca gtcatgtctg gacgatgcca acaacgacga gtgggtcact tgtcctccgg
     8701 gtggaatatt agccatcggc acaatgaaga ttcccaatgc ggacactcca agggactttt
     8761 tcattgcgtt ggacaatgga gacaatgtac ttccggcaga tacggccgat atacgcaaca
     8821 ggaaatacac tgttgcagaa ggtcaaagag tcttcgttgg ctatctgcag atgggagaag
     8881 agaaacccgg atatgagaac ggtaaaatat tcacgataga agatatattg acgaaagaga
     8941 tcattccact gacggaagct acagcagaca gcattggaga cgaccgtatc aacgtcacag
     9001 cgcatgcact tacgaaagat tatctgacca tcgaatatca atatctgggc agcatgaatg
     9061 aaaataaaaa acacatgctg aacttggtac aaaacgaaat aacaggtccc ataaaagatg
     9121 acggatatat ctatctggag ttccggcata atgcctttaa tgactccccc aatcaattgg
     9181 gttcgagcct tgtttctttc aagctggata gtatagccga gcaattggcg acagccaaag
     9241 gaataaaact ccgtgtgaac accatttatg acaatataca gtatgtcaca atagatatca
     9301 acgaagacaa aaacttaaaa ataaaatcat ttcattctca ataaaacaac aagaaacacc
     9361 tacacaatca ggcaaaacga gtaataattc tgatacataa aagaaataag gcggcgatgt
     9421 ttgtgaaaat atcgccgtcg tttttatatt ataccagaca ctgaacggcc tgcagggtaa
     9481 gcatctcctt gggaaccgcc gcctgaatct cctctttcaa aacctgcagc agactggtgc
     9541 ggatgaagtc tttccgggtc accaggacaa tctgacgggt aggccgcggg atagcaaacg
     9601 gacggaccag ttctttctgc tcttcgctca attgcatcac tgccagttcg ggaataaacg
     9661 taatcccctt accactctcc accatatgca taaaggtttc catactaccc agccgatacg
     9721 ccatttggct gatcttaacc gcttccatct gacaaaaacg aaccaactga tcgcggaagc
     9781 aatgcccttc gtcaagaagc caaagccgtt cccctgtcac atcggacgta cgaatcacat
     9841 cgtgcttgaa caacggttcc ttctttgaga catagcccag gaattgctcg taaaataagg
     9901 tctcttccgt taatgcggca tcatccagca tgctggcaat gatagcagca tccgcttcac
     9961 cggtcagcag agccttgcga atgtcgggcg tcttcatctc catcacccgt atatcaagat
    10021 ccgggtattt ctccatcagt tgcggaaaga aacggggcag aagataaggt gcaatcgtcg
    10081 gtaacactgc caatcggaat gtacccgaca gggagtgctg ttcttcgctg atgatctcct
    10141 tgacacagat aacttccgaa agaatcttac gggcctgttc cagcactttc ttaccaatgg
    10201 cagtagggca aaccggtgtc atgctacggt cgaacagttt cacccccaat tcgtcttcca
    10261 gcttctggat cattgcactc aaagtaggtt gcgtcacccg gcaatactcg gcagctttag
    10321 caaaatgccg gaactggtcc acagccagaa tatattccaa ttgttgtata gtcatcgttc
    10381 tctgatttat taaagatata gaatctatca atgcaaagat agaaattttc agtttgacac
    10441 gaatcatttt gtgccgtatc tttgttccag ataaaaagaa gaaatatagt attaactcaa
    10501 aaaaaacaat atcattatga agactttaaa ttatacacat ttggaagaaa aaggagctaa
    10561 caccatcgta ctgtcattac agcaactgct tgccgatttt cagattcatt atgcaaacct
    10621 gagaggattt cactggaaca tcaaaggaca cggtttcttc gtactgcaca gcaagtttga
    10681 agatttatat aatggagccg ccgaaaaggt ggacgaaata gccgaacgta tactgatgct
    10741 gggaggaact cccgccaata aatacagtga ctatctgaag atggcgcaga tcaaggaagt
    10801 ggacggagtg aataaggccg acgacgctct gaatcatatt ctcgaaactt acgggcatct
    10861 gattgcggaa gaacgtaaaa tcctgtctct cgcctcttca cacaacgacg aagtaacagt
    10921 ggccatgatg agcgactacc tgaaagaaca ggaaaagatg gtttggatgc tgactgcata
    10981 caacggataa cagccgaaag ggtgtagcca tctgaccgaa aaggtgtagc catacaaaca
    11041 aaagggtgta gccatcccgg cgggatagct acacccttcc tgttttattc gattcagatg
    11101 atacttgtac gtttggtaaa ttcaataatc tccggaatgt atccgaatgc gagcccggtc
    11161 actgtatccg cacacccata atagatggca atccgtccgg tctccgaatc atgaagcgcc
    11221 gcgcatggga aacagacatt aggcacatca cccatacatt cgtaatcctt ctgaggtgaa
    11281 atcagataag gccccgaacg gaattttact ttccagggct gatcgatgtc aagcagtgcc
    11341 gaaccaaaac tatacacaaa accgttgcag gaagccaata caccatgata gatcagtaac
    11401 cagccttccg aggtttcaat cgggataggc cctgcaccga tcttggtaca ctgccaggca
    11461 ctgtcttcga acggagccgg cgacataaca tgacgatgac gtccccaaaa ctccatatcg
    11521 ggagactcgc tatagaaaat atctccaaaa ggagtatgcc cattatcact cgggcgactc
    11581 aacatcgcaa aacgaccgtt tatcttacga gggaacaaga ctccattccg attgaaagga
    11641 ataaaggcat tctccaactg gtgaaaagta acaaaatcat aggtgtaggc cacaccgata
    11701 gtaggaccat gatagccatt acaccaggtc acatagtagc ggtcttcgat aaagcaaacc
    11761 cgtgggtcat atccatagac ccaggttcca acctcagcat catcacattg aaactttaac
    11821 ggttcttcgt tgatatccca atgaacagca tccttgctga atcccacatg caaacgcatg
    11881 cgacgattag tatcatcaca acggaacacc cctgcatagc catccttaaa cggaactacg
    11941 gcactgttga atatactgtt tgaagtaggg agcaagtcgc gcggaataat cggattggcc
    12001 gaacaacgcc acactacatc tttacatcct gccggacgtt cttcccaagg catagctggc
    12061 aaagcagcac ctgcaatttt aatttcttcc atgattcgat taaattaata ttatgtatat
    12121 atcttgttta tattgaaaat ctctttttat ttcttctttc cgtccggata tgtgaaaggt
    12181 accagccaag tcacgataaa agccggtatg gtagcgataa gtacccagat aaagaaatcg
    12241 cgataaccca gccaatcgct caggtatccg ctcatcattc cgggaagcat cacccccaga
    12301 ttcataatac cggtagcaaa agcataatgt gccatctgat gtttgccggg agccacttgc
    12361 tgcatcataa agagcatcaa tccgacaaaa ccaaacccgt aacccaagta ttcagacaca
    12421 atggccatac caataatcca tagatcggaa ggctggtaaa gggctaacag gaaatatacc
    12481 aagaacggaa tattaaaagc gcaacataaa gaaaacaaag tcttccgaag tccgaaagcc
    12541 gaaatgtaat aaccggccaa aagcgaaccg agaataaaag ctcccgctcc gaacgtacca
    12601 tataccagtc cgatatcctg agtgctgagt cccaatccac catccgcaac cgacgctttc
    12661 aggaacaacg gtacaatctt gatggcatat ccttcggcaa accggtacaa aatgataaag
    12721 acaatgtaga aagcaatatg ttttttttgg aaaaaagagc ggatgacttc ccaaagcata
    12781 ttcaatgcgt cactcatcgt attcacttca ccggaagcgc ctcctcccga aggcaaaatc
    12841 cggatgtggt aaagaccgat cagaatcata atacccgcac acatcaacat gacaatcatc
    12901 caggcatgta ccactccaaa ttcatccttc agcatacctg ccagccaaac caagcctccg
    12961 ttggcaagta tcttggccag attataaaaa gctccctgcc aaccgatata cttggcttgc
    13021 tgggtagcag tcagttcagt caggtatact ccgtcacccg caatgtcatg agtcgcacca
    13081 ctgagagcaa tgatccccat cagagcgatg gcataacgaa aaaagtcggg cagcggcagc
    13141 gaaagtgcta ccaatgcaaa tgccagtccg gtaatgattt ccgtagcgac aacaaagtat
    13201 ttcttcgttt taaacatttc cagaaacgga ctccataaag gcttcaatgt ccagggaagc
    13261 ataatgagag aagtccagaa agcaatctgt gcattcgaca cttccatatc ggaaaacata
    13321 aggacagaaa ccatcgaaag ggccacaaac ggcaatccca tagcaaagta aacagtaggc
    13381 acccaacata cagggcttat cggcttttta ttcatcagtt agttttttat aataattcca
    13441 tcggttaaca attccagtaa gcaaagatag gggatattaa aaacataacc caagattacg
    13501 acaagaagtt gctttcatta tttaataata caactcaccc gggaaaacta ctaacctcta
    13561 tcaccctttt tttattaaac tttatcaata caatacacgc aaagaagcac cgaagacttt
    13621 catccccgat gcctctcgcc cccttatcta caatctaaac acctctattg cttcacatat
    13681 aaatttatct cagcaaaccc ggtataatta tccggagtca gacagtttat tctgaattcc
    13741 tttacattcg ggataggtgg ttcgatggcc gcatattgcg gatcagcccc tttaaaattt
    13801 ctgaaagtca agactctcgg gtaagtaacc cactcggttt caccctcttt ccgaacctta
    13861 atctcagcac ttctcaggtt ataacccgat ccgtaggcac tctgtttagt gaccgaaaat
    13921 ccggttaagg taacaggccg gtccagtagc gtattccacc aacactctcc ggcattagcc
    13981 actccccatg taaaccaagt agtatttatc tcaccgtcaa tagccagatg tgcaccatat
    14041 ttggcatcat catcggcata aacattgctg caacttacac tccacgcact tcgatctaca
    14101 gcggaccaat tcccgggttt cgtataactg gtataaagca cgctggtata aatccggata
    14161 taaaccgtct tcatagatgt actgacagcc tgttcgtcca tgcccgtaac tcctttaagc
    14221 gccacgggaa gcacatatcc gtcaggatta gtcaactttt ctatattctt caaaacgacc
    14281 agaaaagatg aatcggccac tgtctgtccc gtttttaaga caacttcact tgtttcaatg
    14341 gtataattat cttggggcaa caacttacat ttcgtcttat tggcagaatt gtaagtatcc
    14401 actttcagcg tatctactcc caaagcggta gtgacatccc gcgtaaccgg ctgtacggca
    14461 cacaattgta tttcaaaatc agaacggtcg gcagtagagg aattgctcac acaatccacc
    14521 actaccgcag cacccatttc ggcccccggt gcaactcccg ttctgatata tatcttttga
    14581 tatttgtcca tttcatcatc atcgttgctg cacgaagcca acgatacaaa gcctgttatc
    14641 aggcagatta aggtcacaaa attcaaatgt ctattcatat cttatcttct ttttacatag
    14701 ttattgctta tcaaaacgaa catgctcttt ccagacaaga gttcctcctg ccaccaaatc
    14761 gtatccgtgt ccggtacagt cggcaaaggc atttccttta ccttcatcca ttttccaata
    14821 gcctatcagg ttcggatcgg cgggtttcac ggcaaaatac atgttggact gaatttgcgt
    14881 ctggctgatt gcgctcttcc aaagacgcac ctgggccatc tgacaattgt tgcggaagta
    14941 gctaccgctc gaaaccatgt tcatcttgtc gaatcttacc gggccaccct ttgtctgcag
    15001 agtcacgtcg agcactccgt tgatataaat cgacaataac ccggaagaat tataaacgaa
    15061 ggccagatga taccacttat tcttctcaaa caaagtcacc gtattgacct gacttccaag
    15121 tgtcttcacc tgtaatgaat tataagggat catagcgtca ccgaaacgga tataaacctc
    15181 gtggtcgctg ctgcccgaat taaatatagc ctgattatta atatcgaatc cgtccatctg
    15241 tacccaagcc tcgagtgacc attcattggt tgtcactccc cacaattcgt ccttggcggg
    15301 cttcacggca ttggtcgtat tcataaacgg tacagactgt atcagcggct tatccagcaa
    15361 aatgataaac ttcgacgaaa gcccgattgt ggacaccggt ccctgaattt ctgtgagaga
    15421 taccggaata gcatacaatt ctccgttttc gtttgaataa ggtttcactc taaactcact
    15481 ggggattgcg ctaacatcgc ctgccgctat ctttatctct ttgtcataag taaaatactg
    15541 ctcgggaagg acttcgtacg aagtttcatt agcttcattg tactctttaa gaatagaagg
    15601 atctaccgtc aggacagcag tcacattttc ggttacaggc tgtcccacac gtacggtcag
    15661 agtagttgtt gttacatttt caggatcaac ggtaaccttt gccgaaccat tctcggatgc
    15721 ttcattcaaa taaatcgcat tgtcgataac ctggtaatcg gcatcgttgc atcctgccag
    15781 gatcatcggc agaacgaaac aggcaagcaa acattgtttt attgttattc ttttcataat
    15841 caaattcttt aaagtcattt tacagcagga ttcattattc tgattgcttc acgcaggtac
    15901 ttatattcga tgtcgcccgg atagtcatat tccatgtgat aggtgcctac tccacccttc
    15961 cgtacctgtt ttccgtcaat agtcggagtc cagcgtgcca tgccggcaag tgctctcatt
    16021 ttgtttccgt aacgatctac ataatcacct cctcctgtcg gagcataaga ttcgaaattc
    16081 tccgtaacga tgtacatatt agccactttc tccggaggaa gtattccttt aaagttggca
    16141 atcgtaccag ccagacgtct gtcaagatta gcgtcggaat tacccgcaag gttagagtat
    16201 gcctgcacaa tgaaatagtc aaagtaaggc ccggtttccg gatgaatact ttgaggctcg
    16261 ccatcaatca caagtaaccg tcccgtaccc gatttaggtc cgattctttc
//
