LOCUS       gnlProkkaLNJANMJE_41   13764 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LNJANMJE_41.
ACCESSION   gnlProkkaLNJANMJE_41
VERSION     gnlProkkaLNJANMJE_41
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 13:29:44
            Original ID  :: gnl|Prokka|LNJANMJE_41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13764
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13764
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3413:3764]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3414..3764
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13764
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13764
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             258..1769
                     /locus_tag="ctg24_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             1843..2910
                     /locus_tag="ctg24_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             2947..3231
                     /locus_tag="ctg24_3"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3414..3764)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_4"
                     /sec_met_domain="PqqD_RRE (E-value: 3.8e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.4e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(3862..5250)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg24_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5498..5893)
                     /locus_tag="ctg24_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(5900..6673)
                     /locus_tag="ctg24_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6679..7206)
                     /locus_tag="ctg24_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7193..8434)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 387.1; E-value:
                     2e-117)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg24_9"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8444..9538)
                     /locus_tag="ctg24_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9543..10583)
                     /locus_tag="ctg24_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQNQIPLGEASKE
                     AEQTNK"
     CDS             complement(10602..11636)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_12"
                     /sec_met_domain="PF04055 (E-value: 5.3e-18, bitscore: 57.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDNLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
ORIGIN
        1 agtaccacca aatttgacga agaaccagaa atctttttca gggagaaata aaagtaagtt
       61 cataatggtg cagcattgaa ttattttttg gcggagttat tctaacactt aatagttcaa
      121 aagcagatat ttctttgacc aaaagataga actaatgatg aattaaaagt tgcaattatg
      181 gttttcttcc cacaacaaac gggaaaagtc agaagaatca tgtacatttg taatccgaaa
      241 actaaaagaa catcgcaatg aaaatatttc caagcagcag tatcaagaaa ttggacgctt
      301 ataccattga gaacgaacct attgcatcaa tcgatctgat ggaacgtgca gcaaccgtat
      361 taacaaaagc catcacagac agatggaata cggaaacgcc ggtcactatc tttgccggac
      421 cggggaataa tggcggagac gctctcgccg tagcccgcat gatggctgaa aaaggatata
      481 aaatcgaggt atttctcttc aacacgaaag gagaactttc acccgactgc cagaccaata
      541 aagaactggt agaaatgatg gaagaagtaa aattccacga gatcagtacc caattcgtac
      601 ctcccgccct gacgcccgac catctggtaa tcgacggatt attcggttca ggcctgaaca
      661 aaccgttaag cggcggattc gctgccgtag tgaaatacat caattcctcc cctgctatgg
      721 tagtagccat cgacattcct tccggactga tgggagaaga aaacacattc aacgtaaaag
      781 ctaatattat ccgtgccgac gtaactttca gtctgcaact gccgaagctc gcctttcttt
      841 tcgcagagaa cacggaattt gtcggagaat gggaagtgct ggacatccaa ttaagcgaag
      901 acggtattga agagatggaa acgaactacg aaatgttgga aatagagcaa atccgttcac
      961 tcatcaagcc acgcaaacag tttgcccaca aggggaactt cggccatgca ctattgattg
     1021 ccggttcaaa aggaatggca ggagcctctg ttcttgctgc ccgcgcctgc ctccgttcgg
     1081 gagtaggatt actgactgtt catgcaccaa tgtgcaacaa cgacatcttg caaacctcca
     1141 tacccgaagc aatcgtagaa accgacatca acgaaacctg ttttgccgta cctaccgaca
     1201 cggacgacta tcaagcagtc ggcatcggtc cgggactggg acgaaacgag gaaacggaag
     1261 ctgccttgtt ggaacaactg gaacactgcc agactcctgt tgtggtggat gccgacgcac
     1321 ttaatatcct cgccaaccac cgtcatgcac ttacccacct gccgaagggt tccatcctca
     1381 ccccgcatcc gaaagaactg gaacgtctga ccggcaaatg ccaggactct tacgaacgtc
     1441 tgatgaaggc ttgcgaactg gcccgtgccg cccatgttca cattatttta aaaggagcct
     1501 actccgccat catcaccccc gaaggtaaat gtttcttcaa cccaaccgga aatccgggaa
     1561 tggcaaccgg aggtagcggt gacgtactga ccggagtaat cctggcacta cttgcccaag
     1621 gttatcccac cgaagaagcc gctaaaatcg gcacttacat tcacggactg gcgggcgatg
     1681 tcgctcaaaa gaagcaagga atgatcggaa tgatcgcaag cgatattatc acctgtctgc
     1741 cgacagcatg gcgacttgta agcgaataaa agttaagaac ttacagtttt ttcaataact
     1801 tcattaactt tgttttcaaa accagttaaa aaagaaccga atatgaaaaa gttgattata
     1861 gcagcaggac tactaatgac aacgtccgcc tatgcacaaa ccgaagtact gacaggggtt
     1921 acccgaggaa aagactatgg agtggtttac agtcttccca aaacccaaat agaacttgaa
     1981 ataaaagcca acaaagtcaa ctatactccg ggagaattca gcaaatatgc tgatcgttac
     2041 ctgcgactga ccaacgtctc cgccgaccct gaagagtact gggaactggc tagcgtaaaa
     2101 gtgaaatccg taggtgtgcc caacagcgaa actacgtatt tcgtaaaatt gaaggataag
     2161 acagtagcac cgcttatgga actgacagag gatggcattg tgaaaacgat caatgttcct
     2221 tacagcaata gcagtgtagg caaaaaagct gctcccgccc ccgcagtcct ccaaaagaaa
     2281 gcgaatcctc gcgaattcct gaccgaagag attctgatgg ctagctccac cgccaagatg
     2341 gccgaactgg tggctaaaga aatctataac atccgcgaaa gcaaaaatgc cttattgcgc
     2401 ggacaggctg acaatatgcc ttcagacgga gcacagctta agattatgct cgacaatctg
     2461 aatgcacagg aagaagccat gacgcaaatg ttctccggca cctgcaacaa ggaagagaga
     2521 acattcactg tccgccttac ccctgacaag gaatttaaca atgaagttgc tttccgcttc
     2581 tcgaagaagt taggtgtagt tgccaacaat gatttggcag gaactccgtt ttatatcagt
     2641 ctgaaagacc tgaaatcggt caagatacca caggaagatg gtaagaagaa gaaagatttg
     2701 gatggaatcg cctacaacgt acccggacaa gctatggtta cattgaccga cggcaaaaag
     2761 aaactttacg aaggtgaact tcctattact caatttggtg tgatagaata tctggctccg
     2821 gttttgttca acaagaattc taccatcaaa gtttattttg atccgaatac gggaggattg
     2881 ctcaaagtgg acagagaaga agggaaatag aaaaacgaga aagtgaactt ctaaaaaaca
     2941 aagaatatgg ttggtgaagg acatgcattc gacatgatac gccgaataaa agagggacgg
     3001 gaagcttccc gcctacgtcg tgaacgtgct aacgacaagt tgaagcattt aaaccgtgca
     3061 aacgaacctt atccactacc caataccact cccgaagaaa tggaacgtat catccacgac
     3121 tcggagaaaa agaaagagaa agacagcaat tattttgttt ggggaacgct tattatcatg
     3181 ggagtcctga tagcaattgc cgtcatactt tgggctgtat ttatcaaata aataataata
     3241 aattcaccac agaggacacg gaggacacag aggtttaatc ttttttattc actatagagt
     3301 aacacagagt ctcacgtatt gagaatcgta tttatcgctc tgttttactt gcggaaagag
     3361 agagaagaac tctgtgtcct ccgtgtcctc tgtggtgaaa tataaattcc tatttatgcg
     3421 actggtatca ccagttttat aaatccatct ttctgcattt gagaaagata agccgataca
     3481 cgcgactcgt agccctcttc attttgaaaa tggtctgcga gtttttctat aatctcacga
     3541 acattgcgtt ttccatctat cagttcccat acagccgtac cgtgttcttc caatttcaca
     3601 tgaagttctt tcgacattcc tttcggcaca aggaagcgtt gcatccacgg atatttaaaa
     3661 cggggaaagg agagcacaat tgtctcccct tccctttctg ctgtaatatg ttcactgcga
     3721 cagggaatga cctctaacag gttgattttc tctttggcag ccatacttct tattttttat
     3781 ttcagagtat tcatactgat acccttttgt ttacaccttg atacaaaatt cctttgttac
     3841 tttaggtatt gaatttccca gttacttttg gatattcgcc tcttccagac cgtatccctt
     3901 cttcttgttc tctgccttca acatcaaagc cacaatcaga gcaagtacac caaagagagc
     3961 aaaaatagtc atcggcaacg tgtagtcata agtctgtgca ccgtctacta ccggaccttt
     4021 gcaataagta ttcaacaccc atccgatcaa caaaggaaca cccatcaatc cccagttctg
     4081 tacccagaaa atcaatgcgt atgcggtacc caactgtttt tccggaataa tcttcggaac
     4141 agacggccac atagctgaag gcaccaacga gaaggcaaat cccaatataa tcatgatgat
     4201 agtagcaaac caccatatat tcagtatagg cagagcaaac atcgtatgca caaaaataag
     4261 catcactgat ccgattatca tcaatgtggc tcccttaccg atacggtcat aaagcgaacc
     4321 gaacaacgga gtcaggataa tcgcaccaat cggcaacaat ccgggaatcg ttcccgccaa
     4381 cttcggatct acgttatatt tctgcaccat caagtcggca gcatacttga taaaggggaa
     4441 tacagccgag tagaacaata cacatagtaa tgcaatcaac cagaatcctt tattggtaat
     4501 aatatacaca atatctttca tacggaacgg ttcttccggt tccaatccct ctgcatccaa
     4561 agaagcatcc aacttcttat catagaaagt ataaaggaaa aaagcaatcg tacccacgca
     4621 caacataatc agacaaaaca aaatcggagc aggaatattt gtatggaatg tgccactctc
     4681 atccgtagat ccgaaaaagt ctgccaaagg aactgtcaat accatcgcca gagttgttcc
     4741 gatacgtgcc gtagccattt caagtcccat agccaatgcc atttccttgc ccttgaacca
     4801 tttcactata atcttggaaa cagtgatacc agcaatctcc acacctacac caaagatagc
     4861 atatcccaat gcagccaacg tcacctgtgt tttgaatccg aagagcatgg caccttccgg
     4921 aaaagtagta gaaatcgcat agtatttcaa tccacaacca aacaccatca ataagcaagc
     4981 ccccattccg gtgaaacgaa ctcccatctt atccaaaatg ataccaccga agatcagcat
     5041 caataggaat acattaaacc acccgtaagc acttgtgaag aaaccataat caagactgtc
     5101 ccatagtagt tctttctcaa gcatgggttt tagaggagac attacgtcgg tgaggaaata
     5161 gccgcatagc atagtaaatg cgaccaatgc tagaacactc catcggagta cggcggagtc
     5221 attcaatttc tgtttcaaat gttctgtcat tgttatattt aaaaaagtag ttaataatct
     5281 tatacagcca acaaaggtag ttaaatctcg tttgtttcta tcacaaagag attgttttta
     5341 caagaaaaag ttaagtgcgg attacactga ccacgcggaa cattgaaaat ccgtgtaatc
     5401 tgcgtaatcc gcacttaaat atcaaagaaa tgcagcatcc gtctgcacct tcccattaat
     5461 ggttttaccc caaagtctta cttgacgacg gagtgaatta ctctgctgca ggagcaggag
     5521 tttcagtagc cggtgccgga gtttctgtag caggtgcatt ggtagcagga gcttcagttt
     5581 gcggcgcagc cgtacctgcg ggtaagttat acgggttagt ctgttgttct ttctgtgcct
     5641 gttccaacac tgcgtcttta gcaacagcag agcgaggaac tacataagca gtagcaatgc
     5701 tcattacaac cataaagatg gccaggcccc atgttgcttt ttccagaaag tctgtagtct
     5761 tgcgcacgcc catgatggcg ttagatgaag agaaaccaga agcaagtccg cctccttttg
     5821 agttctgaat cagcacgatg aaacacatca acaaggctgc aataaccatt aagataacga
     5881 ataataagta catttttagt tattttgaat tagcgttaat aatcaatttc tccaaaaatc
     5941 tgatttggtc tgcaaagtaa gcattttttt ttggatattt caagcttaat tttttaatta
     6001 tttcaagagc ttttgaatat cgttgctgtt taacatagat ttttgccaaa gtttccgtaa
     6061 aacagctgtc atcttcctct tcttccttta tcgtttcttc ttcggtaagt tcgtccgaag
     6121 aggttggcga agatggcatt tcttctctta aaggtttcat gcagagggga gagtcgctct
     6181 cgctcttttc tataaaatcg tcaatcagtt cgaagccttt gagtttgggc gtttcttcag
     6241 ccggctgttc cgtggccgga gtctcctcca aaaggaaaga ggtgtaatcc atcgaatagt
     6301 cgaaactggt ccgggcagtc acctcttcgg gtactgtgga caagaaagcg tcgatcaatg
     6361 ctaatgtgcg gtctacggac ggttcgtctt tcagcacctc cgtgagaggt actccctttt
     6421 tccgcgcctg cacatcatag cggtcacctt caatcaaccg gaacaactgc cgtctgtctg
     6481 caatgtaaag aactgctttc cgcagttctc caccgaaact aatatcatgg agaatataca
     6541 gattcttcag atacaacaga cgaagtgact gaaaatacgg atacctcgca agaagattgc
     6601 gcagttcgta caaagtatcc ctattcagcg tctcgggatg ctgaatccat tgttgaaagt
     6661 taacagaagt catttatatt accagtttgc tacagttgca ttaaaaattt ggtcggtgat
     6721 ctctttagac atttcagcaa tcaatccgtc ctgtacggca gtcaacaact gggtagagtc
     6781 gtaggtacgg aacgcagaaa actgttgttc aaagtcttcg gcatgattgg tgttgttgac
     6841 aaaacgcaca ttgacggtga tagtcaactt cgtctccgaa gaataaccgt cggcagatac
     6901 tgcctggttg tactgattgt accctgtgat ttctccgtca atctgcaagt cggcattttg
     6961 actcggcttg agcagttgca gacgggtctg ccggatgaag atatctttca ggtcctcatt
     7021 gaatttggtt gccaacggag catatacata ctccgacttg atcgggaagt cggctatcga
     7081 aatggtcttt accttatcat aattgataga cgatccgtta aacttatagg aaacagtgca
     7141 cgcaatgact accaacggca agccgaacag tagcaaaggg cgtattattt tcttaatcca
     7201 attcatattc ttttattttt ctataaagtg tacgctcgga aatattcaag tccttggccg
     7261 cactcttccg ctttccatga tgcctctcaa gtgccttgcg tatcatttct ttctccactt
     7321 cgtccagtga caaaggagat tcttctacat attcttccgt gtcttgtatg tcatcgtcat
     7381 ccttgcaaac cgtaggctgc atggtgtgaa tgatagcagg taccgaaggt tgatgtgccg
     7441 tcactaccgg agtagtaacc accgttccca tttgccctac ctgccccacc tgtccggcac
     7501 gttccgccat caggttgtgc accatcttct tcagctccgc cacttcctgg cgcatatcga
     7561 acagaacaga ataaagaatc tcccgttcgc tctcaaagcc tttactctca cgcgttccca
     7621 tcagcgcggg aagacgttgc gtattttgtg caggaagata attctgcaag atagcagcag
     7681 agatctccct gttggtttca atgatagata tttgctcggt gatgttcttc aactgacgaa
     7741 cgttgccggg ccacgggtaa gccaataact ctttcttcgc atcctccgtc aactggatag
     7801 caggcatccg gtatttctct gcaaagtctg cggaaaactt acggaacaac aaaagtacat
     7861 cgtcaccacg ttcacgcaaa ggcggtattt ggataggcac cgtattcaac cggtaatata
     7921 aatcttcacg gaaacgtcct tctgcaatcg cttgtgtcag attgacattg gtagctgcca
     7981 caatacgaac atccgtcttt tgcactttgg acgaacctac ttttataaac tcgccactct
     8041 ccaacacacg gagcaaacgc gcctgggtag gcatcggcaa ctcccctact tcatcaagga
     8101 aaatagtacc accgtcggct tcgccaaaat accctttccg ttcgccaatc gcaccggtaa
     8161 acgcaccctt ctcatgcccg aacagttcgg aatcaatcgt gccctccgga atagcaccac
     8221 agttgacagc aatatactgt ccatgcttcc tccggctata ttgatgaata atctgcggaa
     8281 aactttcttt tccgactcca ctttctccgg taatcagcac agacaaatcg gtaggagcta
     8341 cctgaatggc aacatctatg gcgcgcgaca atgcttcggt attacctata ataccgaaac
     8401 gttgtttcac ttgttgtatc tctgctctcg tcatcactcg tttttaatct tcgtctactg
     8461 tatccagctt cagtttatca ctatcgtcac gtttctcgta atactgttta cgcaacggat
     8521 tggcacgagc cactttttcc cgctgacgat tacggaacac atcgatggca acatagattg
     8581 cctgacggaa agaatcttca caagccaatc ccttgcctgc aatatcgtat gccgttccat
     8641 gagccggaga agtacgtact accggcaggc ctgccgtata gttcaccccg tcttccatag
     8701 ccaaggcctt gaacggagcc agcccctgat cgtgatacat cgccaggata ccgtcaaaat
     8761 gagtataatt gcctgaaccc ataaagccgt cggccgcata agggccgtag caaaggattc
     8821 ctttctcttc catttctttc atggcaggga taatcacttc ctgctcttcc attcccaaca
     8881 aaccaccgtc tccggcatga ggattgagag agagcaccgc aatacgcgga gcgccgatac
     8941 cgaaatcctg tttcaggcaa cgatggaata tcatcagttt ctcctgaatc agttctttgg
     9001 taatcgtagt cgcgatctct ctgacaggga tatgtgtcgt caccaaagcc acccggaagt
     9061 cattcttcat caaaatcatc aatgacttat caccattgcc cagacgttct tcgatatatt
     9121 ccgtatgtcc ggggaaggag aactcttccg actgaatcgt atgtttgttg atcggagctg
     9181 ttacgataac gtctatcagc ccttcgcgat attcttcgat ggcacgttcc aaagccccca
     9241 gcgcagcttt accggcttcg gggtcgggtt tggaaaattc cactttcacc tcatcatccg
     9301 tacagttcac cacgctcaaa cggttgtacc ccgcttcggt agcagagttg acaatgctga
     9361 aattggtctg tatatccagc gctttgcgat gataagccgc tactttcggt gagccataaa
     9421 tgatcggagt acatagttcc aacatcgtag ggtcggaaaa tgtcttaaga atcacctcat
     9481 agcccacccc gttaatatct ccttgggtga tacctatcct tatcttgtta tcttccatgt
     9541 ttttatttat tagtttgttc cgcttcctta gatgcttctc ccaatggaat ctgattctgc
     9601 tgaacttcat tcggaagttt cagtgtatac agagatgctt ccatctggcg taccaggttg
     9661 cgtttcattt tatcaggtga ataaacaaat atttctgctg ttataattcg ttggtttttc
     9721 tcgtccagac gagtatgaga tacatacggg ccacccataa agtcgccctt catacgccac
     9781 aggccacgtg cttccattgt gtagctgttt tgtacattga tcggacggac atcggtcagc
     9841 aaactatcgg tcgacatata aacgccttcc ttgaatccgg ggatattggc tttcatcacg
     9901 gagtcacgtt tgtgcacaaa atattctttg gtaaacgtat ccttgtcagt gtacggataa
     9961 gagtacatca caaagttacg gtcagcacta cctgtgttgg tagaagccca gaagaaatca
    10021 tccccggtct ttgaattagc cagttcggca tccacccaga tgtcgcatcc gaacaaactg
    10081 tccactttct gcgaaatgaa attactgtgt ttcccttcta gaaacgtaat ctgacggttc
    10141 atttccgcac gggtaaagaa gtcgacaatc gtctttttgt tctcttccac aaacttctcg
    10201 aactcttctt cgttcggagc ctggatagtc aatatcatct gcggattggc atacacgtcc
    10261 ttcgcatatt tgaacgaggc tttcgtatat atatcctgta tatctacaat aataatgtta
    10321 cgtatcaact tcagcgtaga atcataatct ttcggtgaag tatacataat ccggaaagaa
    10381 ggttccgact gcggcaaacc gggcatatca gcatcgagcg catcatgcaa cgcccttccg
    10441 gcagcacgat cccaaacacc gtgatctact acaaccaaaa gctcgtaagc acgaccacta
    10501 gaggtgtgat ttcctttcag accacaagat gcaacgacaa aggctaccaa agcgatgcat
    10561 aaaataaaag agtacttttt catgatgttc ggttttatat attaactttc attatttttc
    10621 tcctgtttcg ctgtcgacag cataccgcaa gcggcaaaaa tatcttcgcc tctggatgaa
    10681 cggatagtgg tgaaaagtcc gtgtgacgtc agattatcac gaaaacgggt catcgtatcc
    10741 atatccgccc cctcgaggtc tacccccggt atggcatgaa aacgaatcag attcaccctg
    10801 caatccagcc cgcgaagaag tttcagcaac tctttggcat agacctgcga atcattgagc
    10861 cctttaaaaa caatatattc aaacgaaagt cgacgttgtt tactaaaatc atagtttttt
    10921 aacagttcca ccatttcggt gattgaaaac gccttttccg ccggcattaa ttcagcacgc
    10981 tgaacggtca gcggagagtg aaggctgatg gcaaggtggc agtcattttc ttcgataaaa
    11041 cgctgcaatc ctttccgtag cccgacagta gaaagcgtga tacgcttcgg actccatgcg
    11101 taaccgtagg tagcggtcag tagttccaat gctttcaata cctcatccag gttatcgagc
    11161 ggctcgccca ttcccatcat tacgacatta gtcagtttgt cccgttccgg cagcgaatga
    11221 atctgattca tgatctggct ggcggtcagg ttagccgtat acccctgttt gccggtcata
    11281 cagaacttac agttcatctt gcaacctact tgtgacgaca cgcacaacgt tgcccggtca
    11341 tcatccggta tataaaccga ctctacaaaa tggttctcac ccactttata aagatacttc
    11401 accgtaccat ctacagagcg catttcatct accggagctt ctgctcccac ctcatagttc
    11461 tgcttgagca actcccggtg tttcaatgac aaattagtca tatcatcaat cgaggctacc
    11521 ttcttttcgt aaagccagga tgcaatctgc ttggcagcaa agccgggcat acccagtctt
    11581 tttgtcaatg attgaagctc tacaagagtc attcctaaaa ggggatattt agacattctt
    11641 ctttctgttg atagtttata tctgcaaatg taaggaaata aagtcgattt ccgtatagca
    11701 ggaatgtaaa agttaacaaa aaagggaagt atgcctccgt tatgattcaa ccacgctgat
    11761 atattgaagt agcttttgcg ccatttcaga atcctcgcca ttctttttca cttcatgacc
    11821 gtacgcctca cggaaacaag ccagcgcctc ttcccgttca ttacaaaagc tgtgcaaaac
    11881 ccctaagttc tgacaagcca gaatcgtatc ttcttcctcc catcccaaat acttctttcg
    11941 cagttcgaac tctctgaaga aagcctcttt cgccattgga taattctcca acttcacata
    12001 agcctgtgct ttgtaataat ataccagaca ggaagcatta gggtcagcat catcgtgaat
    12061 atccaaagac gtcgcaatac gaatcacgtt atcatagtct ttattcatgt aatactgctg
    12121 cataatatca catctcaatg cctcatatcg gacagtcagt tccgccagac gcggtttttc
    12181 gctgaaatac atttcatgca gaagagactc acggaagaat aaagtagacg cctgctcatc
    12241 gccacgttca ttcatcactc gtttgaattc cctgcacaga taatacaact gtttatgaca
    12301 agcgacgatc tgttttttat tatctatctg tatagcaatg tccaacgcct gattcatcag
    12361 catccatgct tcatcgtatc gtttgatata ataaagacat ttaccctgca tacgcaaaca
    12421 tttagccact ccaccggaca gtctgccatt caatgactcg tgcatttcag ctactttccg
    12481 gaatttctcg gcagcactct cttcctcatc cttatagtaa tcacaataag ccagatattc
    12541 ggaaagttca atgacttctg cctgactctt ctcgtcagca aaagccgcat gataatcaag
    12601 cgccctattc aaatagatcg ccgcttcatt gtattgctca ttgtagtaat atgccaaagc
    12661 tagatttcga caggtgttgg caatctccag ttccggagtc ggtactatgt tttcctgcat
    12721 caccaatgct ttcaggaaac agtcgcatgc cgtttcgtat tcttcattac gggcataccg
    12781 gcatccctca ttcatcttca ataccgactt ggctattagt ggcatggcag caccttccat
    12841 actcttctca ctcacagcag ctgccgcctt cgtcagatgg aaagaactgc tcaagaaagt
    12901 agccatatca ttagcaatga caggaattaa aaaagaatcg atctcatcaa agtccaattc
    12961 ggcatagact tcaggcgtaa cttcaggatt gtcgttcatg atcgccttcc agctatcttc
    13021 caacagagaa cgattcgtgc gatacagaat ctcgaaaatc tccacatcac aaatccaatc
    13081 cttcaatata tcccattctt gcatcttata gcattgatag gtaatctcca ctttatagcg
    13141 atacgaatca tggtagcaga actgtttcat gcgatagtta taatcggcaa aagtcaacgg
    13201 atgggaaagg atctcttcct catccagcag agcggaaata atttcatggc gactatcatc
    13261 tatacattcg tcatcttgag cgaaatagcg ttcgatcgcc tctaccattt gtgtgtcacc
    13321 aatgcaatat cgtcctcctt tgttggtgag ccagctgctc atttccactc tcaactgcga
    13381 ccaaagtatc tgattaatgt ctgccatgct cttcacttca tcttcggtaa atccttctaa
    13441 agtaagtgaa agcatcagaa gcgttcttcc aatctcttcg gaaccataat cagccgacaa
    13501 acgccgtagc acactgtcat agaattgccc aacctcattg agccggcaat atccacgcat
    13561 atattcattg agagcatcgt actgaccgaa cgaaaccagc tcgttgagca atacactcaa
    13621 acagcgcggt tgtttagcca gcacccacga agcaagaata tcttcctgct gtgcagacaa
    13681 agccttggag taagtagaca aatattgctt tgagaacgac ttggcatccg cctgtgaaaa
    13741 gccattcaac tggaaatgag cata
//
