LOCUS       c00023_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OEMHDNOP_26.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 15:47:09
            Original ID  :: gnl|Prokka|OEMHDNOP_26
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 134905
            Orig. end    :: 158154
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[144905:148154]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="2"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(115..1206)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_108"
                     /sec_met_domain="Peripla_BP_3 (E-value: 8.4e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
     CDS             complement(1398..2285)
                     /locus_tag="ctg23_109"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGANISYPVVQAADDEYYLKHNFRGEENLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAESK"
     CDS             complement(2282..6991)
                     /locus_tag="ctg23_110"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDTSKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEILVSQIKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGS
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVVQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQIMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGEAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             complement(7194..7655)
                     /locus_tag="ctg23_111"
                     /transl_table=11
                     /translation="MNRKEFLEILRGQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIILLILIIGVALPFFIILAIILYFLSWLKKRNDQ"
     CDS             complement(7883..8761)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_112"
                     /sec_met_domain="CN_hydrolase (E-value: 3.6e-55, bitscore:
                     180.3, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSIAVL
                     DADGKNLGVYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             complement(8863..9966)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_113"
                     /sec_met_domain="PAD_porph (E-value: 8.5e-128, bitscore:
                     419.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGTFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTRED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             complement(10001..11122)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_114"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.7e-14,
                     bitscore: 47.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRIEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTRASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIQIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             complement(11112..12392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_115"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 5.9e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 2.8e-35,
                     bitscore: 114.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             complement(12389..13249)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_116"
                     /sec_met_domain="Spermine_synth (E-value: 4.8e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 7.1e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             complement(13252..14709)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_117"
                     /sec_met_domain="OKR_DC_1_C (E-value: 3.8e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 8.5e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEYLQVLKGGI"
     CDS             15998..17683
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_118"
                     /sec_met_domain="FTHFS (E-value: 6.8e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             complement(17792..19216)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_119"
                     /sec_met_domain="Lyase_1 (E-value: 3.6e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 1.3e-21, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             19332..20267
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg23_120"
                     /sec_met_domain="LysR_substrate (E-value: 6.8e-33,
                     bitscore: 107.0, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 5.7e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSPIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             complement(20378..21835)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_121"
                     /sec_met_domain="FGGY_C (E-value: 1.5e-37, bitscore: 122.6,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 1e-79, bitscore: 260.8,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYSLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARSLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
ORIGIN
        1 taagcactca tctccgtaaa gatcctgtga acctgtacaa aaccagaact tatagtttct
       61 tcctgttttc atgataaaat tcctcccgga tttattttta tttatttcat ttgtttacaa
      121 tatttttctg catgatcccc gtatgatcag ttccggataa atcagtcttt caaccttact
      181 ttcttcttca ggaactccgt tgatcttctc aagtataagc tctgctgcca tttctcccag
      241 cttttcctgc ggatgagcta tcgttgtgat tccgcttcct cgctgagcat acagtgaatt
      301 gtcataaccg gtaatggaaa tatcatccgg tatcctgact cccattttct ccagttcttc
      361 cataacctga acagcaatct gatcattgta acaaacgatt ccatccggaa gctgtccgct
      421 ctgtaccatt tcttttgcca tcagtgcagg ttttactttc ctgtcctctg tatgaaacca
      481 gacaacatca tcaggatcat aggcaatccc tgactcctgt aaggccttca catatccctt
      541 gtggcgctcc agtccctgca tatcgtctgc cttaaagaaa cccttgatct ttttatgtcc
      601 cagttccagc agatattttg ttacaagata gcctccctgt gcatcatcca taagaatatg
      661 aggtttatcc ctcatttctg aatagattcc ctgaataaac acatacggaa tttcaaattt
      721 atccagattc tgataaagat ttctgtgttt acagatcatc tcacttttgc ttggttcaat
      781 gatcagtcca tcaatatctt tcttcagaag ttcctccaga catctggcct ctttctgtct
      841 gctgtttgct gtgtttttca ggataatact gtaaccgctt tctgaaagga cattatccat
      901 tccctgtatc agtctcggaa aaatataatc agaaatatat gtggtcacta ccgcaatatt
      961 ctttgaattc tttatatggc gcatattctc agagcaataa gtacctcttc cgtgaaatgc
     1021 ctctacatat ccgtcctgct ccaggattcc cagtgcttta cgaactgtat gtctactcag
     1081 ggaatatttc tgtgaaagct cgttttctga aggaagcttc tctcccggtc ggatagctcc
     1141 tgacataata tcacttctga gctgttccat cagtgagaaa tatttcggct ttccattatc
     1201 tgtcatgtct tcttccctcc tgtatttagg atacaacttg tacgcacgta cgaacaagtt
     1261 gttttttatg cataaattat acaaaatatc gagagatttt tcattagttt ttcccaaaac
     1321 acctcgaggg atagtgatgt gtgaacagta acagttcatc ctttacgaaa gttaccaata
     1381 tccgattgat ttcaacatca cttcgactca gctttttcta taccataaca ttcatggcaa
     1441 atcccatgta ccgccatacg tatttcttta tccagacgtg aattacaggt gatcagagtc
     1501 accattctct ccctttcatc aggctctact cctgtgtcat acatggaatt atttttcaat
     1561 atagataatt gtctcctgta tgcaggactg gataacttgt atccatattc aaatgccggg
     1621 ctttgggaag atgcctgttc cacagaaaaa attttgtaca gaaactttct ttttggtgtt
     1681 gtgatctcaa tttcaggaca ttttttcaga aattcaggct gttcataacg gttcagattt
     1741 gcaaacatca tattaccttc tatattatgc ccgtaaagaa tactgtggga atctgtaaaa
     1801 ttctttttta tgtcatgttc cagaaaaata catccaaaca gattttcctc tcctctgaaa
     1861 ttatgtttca ggtaatattc atcatctgcc gcctgaacta caggataaga aatattggct
     1921 cccgggacag taatccaggc aaccgtctga gagttgatct ttcttaaatt ttcccaggaa
     1981 atcccgaagg attccctgat ttcatctgta cagtttttgt tttttgattc agaagatctt
     2041 ctctgttttt tcctgcgttt tttttcactg ttttttgtac tactgtcttc atcagttttt
     2101 ttgccatctg ccaataatcc ggcaccttct ctgttcttca cccctgccat ttgggaaagc
     2161 tctgcatatt cctgccttgc tgcaagattc tgttcataac tttttatata gaagccggca
     2221 caatatataa gaagcccaat tgctgctatg atcatactta ctgcaaatgt tctgagtttt
     2281 ttcatttccg cggcataccc tttatatttc ttttcccgga aacagttctt ctgtagatca
     2341 ccacacctcc tgtcagcagt cccattccga taagtccaag aacagccatc attttaaacg
     2401 gtctgacatc tcctgtttta gaacttcctg ccatggaacc accctgatag cttccgtatc
     2461 caccggaata tccacccgaa tttgcgtaac tgctgcctcc gcttccggaa gtcgtgcctc
     2521 cattatttcc accattgtaa gatgctaacg gtgctttcgt cggtacagga gtcattttcg
     2581 ggcaggttcc cggtacagat ggtgttggtg tggcttttgg ctgctccgtc ggtttcggta
     2641 cttctgtagg ttttggtgtc tctgtcggct ttggtgtttc tgttggtttc ggtgttgcag
     2701 acggtgttgg tgtggcagtc ggttctgctt ttgctttcac atatgcctcc tgctgtgcag
     2761 taatttccgg tgaaatatca cctcttgctt tcgctgtgtt tacaattttt tcaggctctg
     2821 tgctttctgt tttaaatacc atttcatagc agacttcaat tttatccata tctgacaacg
     2881 atgctcctgt ctgaattaca aatcctgtat catctgcctc tattttggca tctttcagtt
     2941 ctataccgtt tttcttcaca aaaatgctgt cttttacaat ggaagcccct tgggtttcca
     3001 gtttatcttc gataacaata ttctgatctg tgacatcctc acgcagttgt cttactgtca
     3061 atttatagta tcctttctca ccggacgcat actctttctt atctgattcc ttcacaattt
     3121 ccagaatcgg actgtgtacc tctgtctctg cttccccggt tgcaggtatc ttttcactgc
     3181 tgtctgcaac tgcagtattg tgcactttct gtcctgccag ggctgcatca atcaccgctg
     3241 cctgatattc cacgatcata cttttctgtt cctgacagtc cagaggatta tacattatct
     3301 gctcaaaaag accgccttta tcattatcgc agatactata tctgctatcc ctgaccagtg
     3361 tcctgcctgt tgacatcagg aaagtattat catcattgat ctgtacatca gcatctgcta
     3421 catttccttt ctcatccatc agaatcaccg aatccttcag aagacgtact ccctgagtat
     3481 cgatcacatc ctgcaaagta acattacgcg ccacacatcc ggtctgctcc tgtgtcagga
     3541 caatgcggta tgtaataata tcaccatatt tgtaaaatgg tttgtccgtc gtcttctcta
     3601 ctttaagaac aggcgagttc acccagattt ttgaggagtc ctttactttc tgtgcattat
     3661 ctgcatacgc ctgtgctgta tttacaatct ccatcccatt tacgctttcc tgcgcagtac
     3721 agcggaaatt aacagtcaca ggtgtctgat acggaagatc tgaaatcgtc acgatccatc
     3781 cggttccctg gcgtgtaacc tgacagctga ccggtttttc cactgtttct ttataatttt
     3841 ccggattcag ctgatttcct gcatcatcag ttcctgccac cggattctga acaacagccg
     3901 gaacaccgct tacagtaaca gcatcttcag ctccgtccag agccagccct tcaggaaggg
     3961 aaagatcact gatcacaaga tttcttgcga tagatccctt ctgaagatta ttaaccgtaa
     4021 cctgataatt cacctgttct cctacccgaa attcattttc cgcacgtccg tccccggctg
     4081 ccagatatgg attctgaaaa cttttctcaa tagaaagaac tgctgtattt acatacactt
     4141 ctgcgtcatc ctgcgaaaca ggggcattct gcgcctgcac attggcaaca ttaatgcttt
     4201 ccattccatt tgccgcttcc gtaactgtgc aaaggaaaga aatcataacc ggagtatttg
     4261 ccggaagatc tgaaatgttc agtctccatc cgcttccctc ctgaagaaat tcataattca
     4321 ctggtttctc tgatgtctca ttataaaatt ccggattgag ctggttcaaa acatctttgc
     4381 tccctgctgt cagctgcgta atattctgtg ggattccgct taccgataca tcctctgccg
     4441 atgaaagtgc aagtcctgct ggcataccgg tatcccagac agttacgttc cgggccactg
     4501 tacctgcttt tttattctcc accaccacat tgtactgtac ctgttctccg acctgccatt
     4561 cataatgatc tgcagatttc tcaatccaga attctcctga atttacatat acttctgcat
     4621 catcagatct ctcatctgta ttagcagctt ttacagttgc tgcatttacg ctttcgtgtc
     4681 catttgcctc ttcctgtgcg atacaatgga aaataatcgt tacaggctga ctgtatggca
     4741 cataagaaca ataaaaggaa aatccgttct catctgcatt caactgagaa tccacaggtc
     4801 tcgcttcata tgcctgtcct gttttcttat ccggtacggg atagtttacc tgttgctgaa
     4861 ctcccagtac ttccatgctc tgtgcaccac ctgccagaac cagtccctgc ggcagaccaa
     4921 tatcagtaat agttacatct tttgcgattg ttcctgccgt tacattattc accacgatcc
     4981 ggtaagctac ctgctctcct gcctgccatt catatttgtc tgctgtttta tcaatttcaa
     5041 gctgtggact gttcggccat acttctgcca tatcctttct ggattcctgt tctcccgtct
     5101 caggattgat cagattatcc gctgttgcag tcacaatatt ttcccattcc tgtccattgg
     5161 aatccgcaga tgcctgacat ttaaaacgga ttgtgatcgt ctccccatac ttcagggacg
     5221 gacactctgc tttccatcca ttttctccct gtccggtaag cgtacagttc tcacctccct
     5281 gacttgtctc tacagcatac tgcccttcca gaagctgcag acatgatgga agctcgtctg
     5341 taataacaac atttactgct tttacatcct gttttatctg agaaaccaga atctcataat
     5401 ctatgatatc tcccgttttc cattcatact gagaagtatt tttctttact tccagttccg
     5461 gtggaatcac accctttacc cacactgttt ccgtatccat tgtatctccg cttccgtttg
     5521 tacgttcata actcatggat gcatggtttg gtacaagaat actgtatcca tcctctgcaa
     5581 ggtattttga aatgttaatt tctgattccg gtctctggcg tacttttaaa gtaaatgtgt
     5641 aagtctgatt atctgtaaat gcttcatcct gaaggctctc tgctttggcc ctgcaggtca
     5701 ctttctgtcc ttcaacagca acatcaaacc agtctgtcac tgtctgccct gcatcattca
     5761 caatactgac ttttgatgta tcctctatag taagacaatc ctcaagtata tcctgtacca
     5821 caaaggattt cagtctattg ggtgtcacct ctgcccggat catatactga aattcctgtc
     5881 cctgacgaat gccaaaaggt ttttcttttg atgcggcagc tgcctgttcc catgtacagt
     5941 ttgcctctcc cacacgtttc tcaggtgctt ttttcatctc aacatcgccg aaacaatagg
     6001 atgtaaaatc aaaatatgca tatgctttac agtatttctg tcctttaaag ttcggacaat
     6061 aactgttgcc tgatggatcc agatatttat ttcttgtaat ctctgcccat ctttcctgag
     6121 aaccggcttt tgcaatggca tcttcacgac ttttatccca tttatccagt ctgaactgat
     6181 gacagaattc taccgtaaaa ttatctgtat tataaaaaag attcagccat cctctcggat
     6241 catccggctc aacggaacca aggggtgagc ttacagaatt tccatctacc gtcagataat
     6301 cattgttttt cagaacatat gcattatcca gactgctgtc tgacggaata cggactccct
     6361 gtcccgcatc aatatcacgt atggttccat ggccactgat cggcagtgtt tcttctgttc
     6421 catgcttcag aaactgaaac ttaacctttg cgtatcctac agaataaata aatacaccga
     6481 tactgttttt ggaaaagcca accattggat aagcttcatt atctttccat gcaaacgtag
     6541 ctccgccttt attctgaaca atcgattctg cagtgcgcag atcataacgg ggttctgcat
     6601 tctctactcc cacaagaatg agtctgacat caacaatatt tccatttcca tcttttccta
     6661 cattgttata acgcatccct gcgcttccgg ctttatagtc cgctcctaca cgaacacact
     6721 ctgtatcacg ttcgcttttt ccattgtctg aaaaagcttc cctgtccaga ttatcacacc
     6781 caaaagattc atatgtggta attccgggct gaaacttcat gttaaagcga taaccataat
     6841 ctaccacctt gtcactgtcc catgtttcta cagttaacgg tgccgcctga gttacgcaga
     6901 caggcacaag ccccagaatt gcctgcagaa taaaaagcat tgcaagcagc aaagctccaa
     6961 ggcgttcttt cagtttgaaa ttgtgtttca ttttccgtct cctttccgaa caaaaaatat
     7021 aaaaatgaat gtgggatttt tccctgcacc tggcaggatt aaagaataga aataagttga
     7081 gattgtatga ttataaatat tcaaggggaa ttaatatcgt gaaacaagaa cgtttacact
     7141 taagatttta agattctgcg cagggtttct tttctgaaac cctgcataga ttttcattga
     7201 tcatttcttt tcttcagcca tgaaagaaaa taaagaataa ttgcaagaat tataaaaaac
     7261 ggaagcgcaa ctccgattat cagtatcagt aaaataatta taacagccgc tgctgcaata
     7321 acaacagccc tgccatgcca ggtagaaaga tcgattactt ttttccatct tttctcctgc
     7381 tgatgaggaa gctctgtctc attgccataa ctgcttccgt aagaagaata ctctccgtaa
     7441 tcttcctgtg tacttccatc atctgtatcg atcagagttt ttgctatcag atgtggatct
     7501 cccagttcct gcagtacctc ctgctctgaa cgtccgccac gtacctgaga ctgtatataa
     7561 tcttcataat acctgatatg tgctgctgct ttgccctcct gcatctgccc ggcaagctgg
     7621 cctctcagga tttccaaaaa ttcttttctg ttcatcttct acactccatt ttgccagaaa
     7681 tacatatcaa aactctactg ctcgctccgt tatcagtaac gttcgtactc ttattttacc
     7741 atatataccg caggtagcaa ctaatataat cataaacttt ttatgaaatt cttataaact
     7801 cagttactgt tcactccgtt ctcagtaact gagccaaaat tcattccaga ttgcctgcgg
     7861 caatggaatt ttggcttgta tgtcatttcc cgacaatttt tgcatacatt tcaggtctgc
     7921 ggtctctgaa aagtccccag ttcagtctgt ctgcctttaa tgcatccagg tcaaaagtgc
     7981 ttacaagcac cccctcttcc cctccgggca gttctgcaca gagagcacct gtgttgtctg
     8041 tgataaaaga agagccgtaa aaattaagag cagatttctg cattccgttt tccggacatg
     8101 gctctactgt ttcctcaccg attctgttgg cagcgatcac agggatcagg ttggaggcag
     8161 cgtgtccctg catacatctt ctccagtgtt ccatgctgtc gcattccagg atgggttcac
     8221 ttccgatggc agtgggataa aagagaagct ctgctccctg cagtgccata catcttgccg
     8281 tttccgggaa ccactgatcc cagcagattc caactccaat ggttccaaat ctggtatcaa
     8341 aaaccttaaa gccggtatct cccggtgtga aatagaattt ttcctgataa taatggtcat
     8401 ccggaatatg tgttttccgg taaacgccaa gattcttccc atctgcatcc agaaccgcaa
     8461 tgctgttata ggtattattg acctcttttt cataaaagct gaccgggatc acaatcccca
     8521 gctctgccgc taccctgctg aaatgacgca ctgcagggtt ttcctctgca gtctgcgcat
     8581 attcataata ctcatatctg cgctcctggc agaaataggg ccgttcgaaa agctccggaa
     8641 gaagaacaat ctcagctccc tttgctgctg cctgacgcac cagttcctct gcatgggcaa
     8701 tatttttctc cacactttta ctgcatttca tctgaactgc tgccactgtt acatttctca
     8761 tcctgtctgt tcctcctgct cctgtttaca taagtaagtt ttttcataac tttcaggtaa
     8821 taaccctcaa acacatgact ctcaaagttt tctgcatcag ggtcagatat tttttccggg
     8881 aatctgctgg gtgatacagt gaatatttcc accgccaaca atgatggctc tggcatcaat
     8941 gggataaatc cttctctctg gaaaacactt ctgcagaatc tccactgccc ttttgtcatt
     9001 ttcatcccca aactgaggaa gaataattcc tccattggaa atataaaaat tcacgtaact
     9061 ggcggccatc cgttctcctg cttcccgttc gtcttctccc tcttcaaaca caaaaccatc
     9121 cacatcttcc cgggtaaggc agaccggttt ctgaggaatc ggaagcttat gaatcttaaa
     9181 ttttctgcct tttgcatctg tttcctgttc cagcaccttc agatcagcca gagacatggc
     9241 atactgcgga tctgtctcat cctctgtcca tgcaagcaca acctctccgg gccttacaaa
     9301 agcgcacacg ttatccacat gctcattggt ttcatcctga tagattccac atggaagcca
     9361 gataatcttg tggacaccga gccagtactt caactgttcc tctatctgtt ccctgctcat
     9421 ctgaggattg cgtccctgac tcagaagaca ggcctctgta acgatcagag tcccctctcc
     9481 gtcagaatgg atggaaccgc cctcaagcac aaaaggtctg gcatccagac atggacaacc
     9541 aagagtcctg cagataaagg cagccaccct gtcgtccttc tcccagttcc ggtaaagtcc
     9601 atcaaaggta cctccccagg cattaaactg ccagtcaact ccacagacgg cccctttctc
     9661 atccagaacc atggttgctc ccacatctct ggcccaggcg tcatctgtct cgcattccag
     9721 caaagtcaca ccggaaacat tcccaagctg attctttgca ttctccatct gagctttgga
     9781 aaccagcata tacacctttt cgctctctcc aatagcctct gcaactttca caaatgcttt
     9841 ctgtgcttcc cttgccccat aattccagga accgggacgt tccggccaga tcatcacaca
     9901 tccctcatga ggctcaaatt ctccgggcat acgatatttt gttctgttct tctctgtaac
     9961 ttccatgtct gtctcctttt ctttgatagc ccggcagata tcaggaaagc cggctcttaa
    10021 agtcttcgta tccgaaatgt ctgataacct cacactctcc gtcctcatgc ataaccgcaa
    10081 tatccggcag cggcataccg ttaaatgtat tattcttcac catagaataa atcgccatat
    10141 ccataaaata cagcttgtcc ccgatctgga tctctctgtc aaaggaataa tctccgatca
    10201 catctcctgc caggcaggtg caggaagata agcggtaggt atatgccttc tcccctgctt
    10261 ccccgctgtc cttaagaggc ggacgatagg gcatctccag cacatccggc atatggcagg
    10321 ctgcagaagc atccaaaatc agcgttctga tctcattttc cacaatgtcc ataacctctg
    10381 tcaccagata tccggcattc agggcaacag cctccccggg ctccagataa atatccagat
    10441 cataggtttc cttcatatgc tgaatacatt tttccaggag ctttacatca taatcctctc
    10501 tggtaatatg atgtccgccg cccatattca gccaggaaac ctcagacaga aattctccaa
    10561 acttctcctc taccgcctgc aatgttttct ccagatcatc cgcattctgt tcgcagagcg
    10621 tatgaaaatg cagtccgtca atccatttca gacattcccc gtcaaagttc tctctggtaa
    10681 cccccagcct ggaacccggc gcacagggat catagattgc atgatccccc tgagtggaac
    10741 attccggatt aatacggagt cccagactgg ctctagtaca cacttcttta aatttcttca
    10801 gctgtgctgt ggaattaaag ataatatggt cacagatccg atccagttcc tctatatctt
    10861 ctatacggta agcaggggaa aaaacatgat tctctttccc catctcttca tatccaagcc
    10921 ttgcctcaaa cagaccgctg gcagtggtac ctgccagata ttttccgatc atgggataca
    10981 gggcaaagcc ggaaaacgct ttctgcgcca gaaggatctt acacccggta tcctcctgga
    11041 cttttttcaa aatctccaga ttctcccgca tcttcttctc atcgatcaca tagcagggag
    11101 tttgcagttg atcaatcttc attggctttc cagaccttta ccagttcagg atcttcgcag
    11161 actttccatg gaagtcccca tttgttcagt gcttccatat atggatccgg atcaaattct
    11221 tccacattaa atacacccgg cttcttccac tgtccggtca ctaccatcat ggaaccgatc
    11281 atagccggaa cacctgttgt ataggagatt gcctgggatt ccacctcttt atagcattcc
    11341 tgatgatcac atacattata aatataaata cttttctctt ttccgtcctt aacacctgtg
    11401 aaaatacagc cgatatttgt tttacccact gttctcggac ccagagatgc aggatccggc
    11461 agaagagctt tcaaaaactg gatcggcacg atctcctgtc cattaaattc cacaggtgcg
    11521 gtggaaagca ttcctacatt ttccagacat ttcatatgtg tcagatagct ctgtccgaat
    11581 gtcataaaga aacggatcct ctgtactccc ggaatatttt ttgccagtga ttcaatctct
    11641 tcatgatgaa gaagatacat atccttcttt cctacctcag ggaaatcgta gacagattta
    11701 aattccatag gctctgtttc tacccaatgt ccgtcttccc agtaggaacc atttgcggaa
    11761 acctctcgaa gattgatctc cgggttaaag tttgtggcaa aaggatatcc atgatcaccg
    11821 ccgttacagt ccagaatatc aatggtatgg atttcatcaa aataatgctt caaggcatag
    11881 gcactgaata cactggtaac acccggatca aaaccggttc ccagaagagc agtcagtcct
    11941 gcttccttaa atttctcatc ataagcccac tgccaggaat aatcgaaata tgcagtaaag
    12001 cctttttctt tacatctctt ttcgtagatt gcacgccatg tgggatcttc tgtatcctct
    12061 gcttcataat tggcagtatc aatataatcc gcaccggctt ccagacatgc atccatgatg
    12121 gtaagatcct gatatggaag tgccacattc aggacagcat ccggcttata ggctctgatc
    12181 aattctgcga cctctgctgc attatccgca tctacctttg ctgtctcaat ttttgtcttc
    12241 gttgtacttt caatcttctc tttgagtgca tcgcattttt cctttgtcct gcttgcgatc
    12301 ataatctctg taaaaacatc gctgttctga cagcatttgc gaattgccac tgaagctacc
    12361 ccaccacatc cgattaccaa taatctgctc ataaactgtt ttcctcctct tccagtaaat
    12421 cttctacata ttttggaagc ataaatgctc ctctgtgaag gtttgttgta taataccatg
    12481 tttctatatt aagattatca aacctctccg gcctgaaatc ttccagtgga tgatatttct
    12541 ttgatgcaaa tccaaaaagc cagtatcccg agggacaggt agggatatgt gcctgataaa
    12601 ccctgctcac cggaaatgac cggaaaacct ttctgtgcat ctttctgcat tccacctcat
    12661 cctcatcata aaaaggactt ccatgctgat aaaccatgat tccgtcatct ctgagagcct
    12721 tataacagct tccgtagaat tcctttgtaa aaagtccctc tgtatgtccc agcggatctg
    12781 tggaatcatt gatgatcagg tcatatctgg cctttttatt ccgcaggaac cgaaggccgt
    12841 cttcataata aatgttgact ctctcatcct tcagtccctg ggcaatatcc ggaaacatct
    12901 ccgcacatac atccacaaac attttatcgg attccaccac atcaatgctc tcaatctgtg
    12961 gataatggat cagttctctg gcaactccac cgtcaccgcc gccgatgatc agaacatttt
    13021 ttacattggg atgtactgtc attggcacat gcgtaaccat ctcatcataa ataaattcat
    13081 ctttatcaga gaatacgatc tcaccgtcca gagccacaaa tcttccaaat tcttcagact
    13141 caaacacatc gattctctga aattcacttt cccctgaaaa taactgtcgg ttaatccgga
    13201 cagaaagctt tacatttcct gtatggaact cggaatacca taattccatg atcagatacc
    13261 ccctttcaga acctgaagat attctacctt cggatcctcc attccctgca tggaacagcc
    13321 tttgtctctt gcataaagaa tgtattctac aatttcctgt gtcaccattt ctccaggagc
    13381 aagaatcggg attcccggag gataacacat aacaaattca ccgctgatcc tgcctgccgc
    13441 ctgttccatg ggcagagatt ctttctccgc ataaaatgcc tgctgtggag acgccaccac
    13501 tgcaggtgcg atatattccc cggaaagcat acctgtgctg tccttcttgt acagacgttc
    13561 aatatcagcc aatgccccta ccagtctctc aatatcctga agcctgtctc cgatggaaat
    13621 gtaagccaga atattacaga tatctccaaa ctcgatctga atatcatatt catctctgag
    13681 aagatcataa acttcaatac ctgccagccc atttcccagt gtataaatag agagttttgt
    13741 aacatcaaaa tcaaaaacac tggttccatt gatcagatcc ataccatatg cataataacc
    13801 gccgatctca ttgatctcct ctctggcata ctgcgccatc cctgcaacct tttcaaagga
    13861 ttcctctccc ctgagtgcca gatttcttct ggagatatcc agactggaca acagaagata
    13921 agaagcgctt gtggtctgag tcagattgat gatctggcgc actttctctg cattcatact
    13981 cttattcaaa agcagcagcg aactctgtgt cagacttccg ccggatttgt gcatggaaac
    14041 tgccgccatg tcagcacctg ccgccattcc ggatacagga aggtttctgc cgaaataaag
    14101 atgggttcca tgagcctcat ctgccagcac cttcattcct cttgcatgag ccttctttac
    14161 gatagtccgc agatccgaac agattccata ataggtaggg ttatttacaa gaactgccac
    14221 cgcatccgga ttctcatcca tagccttctc cacctggctg acttccatgc caagggaaat
    14281 gcccagctgc gcattcacct ccgggtttac ataaaccgga attgcaccgc acagtaccag
    14341 ggcattgatg gcacttttat gtacatttcg cggcagaatg atcttatccc ctgccttgca
    14401 gacagacagg atcatgctct gcactgcaga tgtggttcct cctaccataa ggaatgcatg
    14461 cgctgcgcca aaagcatctg ctgcaagctc ctccgcttct ctgatcaccg aaaccgggtg
    14521 gcagagattg tccagcggct tcatagaatt aacatccagc cccacacatt tctctcccag
    14581 caactgcgca agctccggat ttcctcttcc tcttttatgt cccggcacat caaagggaac
    14641 gactctcttc tttcggaaac gttccagtgc ttcatatatg ggcgcatgct gttgtctttc
    14701 ataatccatt tgacatgttc ctcttttcct gtcgtcatgt accggcaaat acagttctat
    14761 cattcagcaa ttgtatactg cctcaaaccg gcacaatgat tcaattattt ctctatatat
    14821 tcaagtcgaa cgcatgtgag acacatcctc gcaaagcgtt tatctccaac catatccttt
    14881 atatttgcta tatctgcaca aaaaaagaag cagataagtt cattcaccat ctgcttctct
    14941 catgatctat agaatttctc aggctctgtc tctttatata ctgaccggat ttcccgtata
    15001 aatccgtctg tatcctgtgc ctgttcccgt attctgaaat attcatgact gctgtcgtct
    15061 tcaatcgctg gcaaatatat gctatgctct tattgaccgt ttcacaagat gatgtgtgct
    15121 tacgcactga ttattataaa gtaatcaact tataaaattt gagcttctaa ctcaatcaat
    15181 aatgtggtgt ctcccacccg gcaactgccc cgcctgtccg tatggcttaa cattcagaaa
    15241 ctgtctctga atgtgagcaa atatttgcat gaaaacgata gtgtcttttc atactaaaga
    15301 tgagaataac atatcttctg aactgttgtc aattccattt tccatatttt gcactagagc
    15361 gtgtctgaaa aaggctttct gcaagatgtg cgtcacaatt tgtgggatat tttgcccgga
    15421 tgagggcgcc gtagcgggct acggcaactg aattcgagtg aaatatcccg caaagtgggg
    15481 gcgtacagat tgcgggaatg atttttcaga cacgctctag ctttacccgc tttttatatt
    15541 ttcttcattt atcagggaaa actgtgttta ttttttaaca atttctttcc ttgagaaaac
    15601 gtattttctt tcatgaccag ggattacgat tctcttctct tatcaatttg cacaactttt
    15661 atccagttta ctcacatttt ttgacgtttc aacaaaattt tcttgacatt tttttctcaa
    15721 aatgatatat tgtattcatc aattgaaaga accttcgagt actgacggaa agagtggagt
    15781 gcaaaccacg tggagtcgga ggtttgtggg agccgaccgt ctgggcagta tttgaaatat
    15841 tcagatactg gccttttttt ataactttca gggcagaaat caggaatacc aggcagaccg
    15901 gccaatactt ctttcaatta ataattgttg ctgatcgcgg agtgaacagc aacagaagtt
    15961 tttcatgtta tgcggaaacg aaaggagaaa aacaattatg ggattcaaat cagacattga
    16021 aattgcacag gaatgcgaaa tgcttccaat tactcagatc gcagagaaag caggtattga
    16081 cgacaaatat ctggagcagt acggaaaata caaagcaaaa atcgactaca atcttctgaa
    16141 agaaagtgat aagaaggatg gaaaattaat cctcgttaca gctatcaacc caactccagc
    16201 aggagaaggt aaaactacta ctactgtagg tcttgcagat ggtatgcaga gacttggcaa
    16261 gagtgttatg gtagctcttc gtgagccatc cttaggaccg gtattcggtg taaaaggtgg
    16321 tgcagcaggc ggcggatatg cacaggttgt tcctatggaa gatattaacc ttcacttcac
    16381 aggtgacttc catgccattg gcgcagctaa caacttactg gcagctatga tcgataacca
    16441 tatcttccag ggcaatgcat taaacatcga cccacgtaag atcacatgga gaagatgtgt
    16501 agatatgaac gaccgtcagc ttcgtaacgt agtagatggt cttggtggaa agacaaacgg
    16561 tatgcctcgt gaagacggat acgacatcac agttgcatct gaaatcatgg cagttctctg
    16621 tcttgcaagc gacatcaaag acctgaaaga aagattatcc aagatcatca tcggatatac
    16681 atacggaaaa gtttccgagc agaaacctgt aacagcaggt gaccttcacg cagaaggcgc
    16741 tatgacagcc ctgttaaaag atgctctgaa accaaacctt gtacagactc tggaacacgt
    16801 tcctgcaatc gtacatggcg gaccattcgc aaacatcgct catggatgta actctgtaac
    16861 agctacaaag atggctatga agcttgctga ttatgcaatc acagaagctg gtttcggtgc
    16921 tgaccttggt gctgagaaat tccttgatat caaatgccgt atggctggtt taaaaccaag
    16981 cgcagttgta atcgtagcta cagtacgtgc cctgaaatac aacggcggtg ttgctaaagc
    17041 tgaccttaac aatgaaaacc tggaagctct tgaaaaaggt atcccgaacc tgttaaaaca
    17101 cgtttccaac atcaaaaacg tatacaaact tccatgtgtt gttgctatca acgcattccc
    17161 tacagataca aaagcagagc ttgactttgt agaagctaaa tgtaaagaac tgggcgttaa
    17221 cgttgctctt tctgaagtgt gggcaaaagg cggcgaaggc ggaatcaaac ttgcagaaga
    17281 agttatccgt cttgttgaag aaccaaacga cttctcctat gcatatgaac tggaaggttc
    17341 tatcgaagac aaactgaacc agatcgttca gaaagtatat ggcggtaaga aagtagttct
    17401 gacagctaac gctcagaaac aggcgaaaca gttagaagct cttggctttg gcaactgccc
    17461 gatctgtgta gctaagacac agtacagctt aacagatgac cagactaaac tgggtgctcc
    17521 tactgacttc gaagttacag tacgtaacct gaagatttcc gctggtgcag gattcatcgt
    17581 agctcttaca ggcgagatca tgacaatgcc aggtcttcct aaagttccgg ctgctgagag
    17641 aatcgacgta gacgagacag gtaagatcac aggtctgttc taatccagtt gaaatcaatc
    17701 gaataattca aaaatataaa aatcatattt atatatgata tgtgtccaga cgattttaca
    17761 ggcgggaaaa ttttcccgcc tgtttttttc tttatttttt tataagataa tcttttccgg
    17821 aaataccagg ttccgtcata tggatcggat ccagaatgcg attaagttca tcctcgtcca
    17881 taagcttttc tttcagaatc agacttctta cagattcgcc tgtcttaatt gccttttttg
    17941 caatatccgc agccttctga tatccaagat gggggctgat tgcagtgata atacctacac
    18001 tgttttctac cagataacgg catctttctt catttgccgt aattcctaca atacaattat
    18061 ccaccaatgt ctggactgca tagccaagag tatcgataga ctggaacatg caatagaaaa
    18121 taatcggctc aaacgcattt aattccagct gaccagcctc tgcagccatg gtaatggtaa
    18181 catcattacc aataatatta aaagcaacct gattcactac ttcaggaata accggattaa
    18241 ctttacctgg cataatagag gaaccattct gttttgctgg aagattgatc tctccaaaac
    18301 cagtacgtgg accggaggac atcagacgga gatcatttga cattttggaa agagttaccg
    18361 cacatgcttt cacagcaccg gaaacagcta caaatggatc cagattctga gtggaatcaa
    18421 tcaaatcaaa ggcctgtata aagtccattc ctgagatttc agtaagattt ggaacaattc
    18481 ttctcagata accttcatct gcattaattc ccgttccaat agcagtgcct cccatattaa
    18541 gagtccgcat ttcatccatt gctttatcca ttctgtggat atcacgcatg attgctaccg
    18601 aatatgcctt aaattcctgt cccagacgaa tcggcactgc atcctgcatc tgtgtacgcc
    18661 ccatttttat tatgtgatca aactctgtag ctttttcatt aagagcatca tataggcgaa
    18721 gaagctgttt tttcagattc tgcaacaaac gaagagaagt cattttaccg gcagtaggaa
    18781 taacgtcatt ggtagactgt ccacaattca catcatcgtt aggatttata attgtataat
    18841 cgcccttttt tcctcccagt atctcaatcg cgcgatttgc aattacttca ttggcattca
    18901 tatttaaaga tgtgccagct cctccctgaa caggatccac aataaattca ttatggaatt
    18961 ttcctgaaac aatttcatca catgcctgga caatcgcctg tgcttttttc ttctcaagaa
    19021 gccccacctc acaattggtt atcgctgctg ctttttttat gtatgcaaga ctgttaataa
    19081 tttccggatg catattcagc cccgtaatgt gaaaattttc agccgcacgt aaggattgta
    19141 ctccataata tacatcttcc ggaatatcct ttacaccaat agaatccctt tctacacgat
    19201 agtctgtttt tttcatagtt attcgccctc ccatgtattt gccctcatta tatatctctg
    19261 ctataatata atcaaataca tatattttta taaaatatat agtgtttaaa ttatatatcg
    19321 gaggagttta tatgtttcag ggaatggaat acatctatga ggtctacaag gaaaaaagct
    19381 tttccaaagc tgctgctgct cttttcattt cgcagccttc tttaagcgcc aatgtaaaac
    19441 gtgtggaaaa ccgtattggc tatcctattt ttgatcgaag taccaaacct ttgcagttaa
    19501 ctgaagttgg aaaacattat atacaggctg ttgaaaaagt catggatatt gaaaataatc
    19561 tcgaaaacta cctactggat ctgggaaatc tcaaaacagg aactcttaat gtaggtggca
    19621 gtaacttttt ttcttcgtgg attctgcctc cccttattgc tgatttttcc caaaaattcc
    19681 cccatgttca aatctctctt gtagaagaaa gtacagcaaa gctatcccag tttctccagg
    19741 ccggaaagtt agatctggtg attgataact gtattctgga taaccagatt tttgaacgtt
    19801 atatctacca gaaagaacaa cttcttcttg cagttcccaa aaattattca gtaaatacca
    19861 gactgcagaa atatcagatt cctattgagg aaatccggaa cgggcagttc cgttcttctc
    19921 ctattccttc tgttccatta aacaaattcg agaacgaacc atttattatt cttcgttcag
    19981 ataatgatac cggtaagcgt gcacttacca tttgtcagga aaatcacttt tcgccttctg
    20041 tagtatttcg cctggatcag cagatgactg cctataatat tgcatgtttg ggaatgggta
    20101 tcactttcat cggggatctt ctgctctcca gagttccaac aaattcagaa cttgtttttt
    20161 ataagctgcc cggtcagagc agtaaacgca ctgtgttttt ttactggaag aaaggccgct
    20221 atatcagcag agccatggaa gaattcctga agctgccctt ttcctgatat gtcataatca
    20281 ataggctatg gtgattggtc atcatcagat gtacgtcaaa atggggttgt tgtgctaaat
    20341 aagcacaaca accccagtat gtcaggcaga tattcgatta gaacaatggc ttcatcgccg
    20401 gatacagagt tctgaacttc tgatatctct cttcatattt tgcaaccagt tcaggatccg
    20461 gttctactgt atcaacaact ttggcaaatt tcttaccgat ggtttctaca tccgggtaag
    20521 caccacagcc tactgctgcc agcatagctc cacccatgga cggtccttct tcgttctcca
    20581 gaacatcaac cttcaggttc ataacgtttg caatgatctt cttccacagt gggctcttag
    20641 ctccgccacc gcaaatcttg gttctctcaa tcttgattcc aaggcttctt gcaacttcca
    20701 gggaatcacg aagaccaaag gcaacacctt ccagaacagc ctgtgtcatg tctgctcttg
    20761 tgctgtccat ggacattccg aagaatacac ctcttgcatc aggattatta tgaggtgagc
    20821 gctctcccat cagatatgga aggaagaata catgattctc tcccagcttc tgaatcggag
    20881 cctgctctgc tgcgaagtcc tttgtctgaa gaatctcctc tgcccaccat ttgttacagg
    20941 aagctgcgct gagcatacat cccatcagat gatagcttcc gtctgcatga cagaaagaat
    21001 gaagtgcgtt attttcgtcc acaccaaagt tcttgctgga aataaacaca gttccggatg
    21061 ttccaaggga aatattacac tgaccgtcgc caactgtacc tgttcctaca gcagctgccg
    21121 cattgtcacc tgcccctgca acaaccttta cattctcact gaatccaagt tctttcgcaa
    21181 tctcaggttt cagagttcct actacttccc agctctcata cagtttcgga agctgctctt
    21241 ctgtgattcc acagatctcc agcatttctt ttgaccagca gcggttcttt acatcaagaa
    21301 gaagcatacc ggaagcatca gaaacatctg tacaaaaaga accggacaga cgatatgcca
    21361 gataatcctt aggaagcata atctttacta ccttcttaaa gttctcaggc tcatttttct
    21421 gcatccagag gatcttcggt gctgtgaagc ctgcgaaagc aatatttgct gtatactgtg
    21481 aaagtttgtc ttttccgatc actgtattca gatattctgt ctcttcgcct gtacgtccgt
    21541 cattccagag gattgcagga cggatcacat tatcatcctt gtcaagtgtt accagaccat
    21601 gcatctggcc gccaaaacca attcctgcta cctgcgctct gtcgatatcc tttgtcagct
    21661 ctttcatgcc ttccatactc tgcgcaaacc agtcttccgg tttctgctca gaccagcccg
    21721 gatgtggaaa gaataaagaa tattctctgg atacgatgtt acagattttt cctgattctt
    21781 ccataagaag cagttttaca gcggaagtac caaggtcaat accaatataa tacataagtg
    21841 ctctcctttt ctatttctaa tctaatacat cccagagcaa agccccggga tgcctttaat
    21901 atagtgtcag tttatttatt ctgtattcag attcattcac ttcacatgaa cattaataat
    21961 ccgttttact gatttttcat taaccccatg gattttctgt cgggtatctt acgcctgccg
    22021 gctggttgta tccaatcttc ttaacatcca gtccaaggaa tttcactacc tcatagaatg
    22081 cttttccgta atgtccaaac ataactgctc catgatgcgg atagttgccc tcgatcagta
    22141 cgtgacggta gaatcttccc atttctttga ttgcgaaaat accgatacca ccgaatgatc
    22201 ttgtaggtac atccagtact tcaccttctg caacataaga aaccagctcg ccctcggaat
    22261 tgcactgtaa acgatagaat gtaatgtcag atgcagcgat atcaccttca agagttcctc
    22321 ttgtgaagtc tggttcagat cctgccggct caagaagtct gtgctggatc agctgatatt
    22381 taacagctct ggaatcacac atcttgcatg caggagtatt tccacaatgg aatcccataa
    22441 atgtatcagt aagcttataa tcgtattttc ctttaatatc ttcatcatag atatactgtg
    22501 gaacagagtt gttgatatca agcagtgtaa ctgcatcatt ggaaatgcaa agtccgatgt
    22561 actcgctgag tgctccgtag atatcaacct cacaggatac cggaattcct ctggaaacca
    22621 gacggctatt tacatagcaa ggttcaaatc caaactgtga cgggaatgca ggccaacatt
    22681 tgtcagcaaa tgcaacgtat tttcttgctc ccttatgagc ctctgcccag tcaagaagtg
    22741 taagctcaaa ctgtgccatt ttcacattaa ggtcagcata atatttgcct tcgcccatct
    22801 cttttgccat atctgcacaa acttccggga tacgaggatc attttcatgc tctttgaaag
    22861 aaacaagaag atcaagctct gagttctctt caatctcaac acccagctca tagaggcctt
    22921 taataggtgc gttgcatgcg aagaagtcct gtggacgtgg tccgaaagta atgatcttaa
    22981 gattgctgac accgatgact gcacgtgcaa ccggtacgaa atcagcgatc atctttgcaa
    23041 tatcatctgc tgttccaaca ggatattccg gaatatatgc tttcagatga cgcattttta
    23101 agttgtagga gcagttaagc ataccacagt aagcatcacc tctgccgttg atcatatcac
    23161 cgtcaccttc tgctgctgct acatacatac aaggtccgtc aaatctctct gcgatcagag
    23221 tttcaggagt ttcaggtccg aagtttcca
//
