LOCUS       gnlProkkaCDHBOPON_1    13544 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CDHBOPON_1.
ACCESSION   gnlProkkaCDHBOPON_1
VERSION     gnlProkkaCDHBOPON_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 13:30:19
            Original ID  :: gnl|Prokka|CDHBOPON_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13544
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..702
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MVSGIAVVLMILFMFFFVKSVNIEKNILEVKNRAVEQQYQELEDA
                     YQKYRCIIHDQKHMLSFIQECIENKDLNGIAAYVADNQKKFRDEEKKFWTGIDVLDKTI
                     TMKKRKMDALDINFELDASVDDTIINTTDLVIILSNLFDNAIDAAVKSKEKKICLRIKN
                     INDVLMMKMWNTSTRIPDVKRGKFVTDKLEAEGHGWGIESVKRLVKRYDGNITFKYDSD
                     FFQVIIILSKS"
     protocluster    1..13544
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[862:3544]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      863..3544
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..13544
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13544
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             718..846
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MTEEFIGCIEEELKEIELFYEENGVEVEAYTLHNGSFFSICC"
     CDS_motif       718..822
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MTEEFIGCIEEELKEIELFYEENGVEVEAYTLHNG"
                     /locus_tag="ctg1_2_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       823..846
                     /prepeptide="core"
                     /locus_tag="ctg1_2_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="769.9"
                     /monoisotopic_mass="769.3"
                     /core_sequence="SFFSICC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTEEFIGCIEEELKEIELFYEENGVEVEAYTLHNG"
                     /leader_location="[717:822](+)"
     CDS             863..3544
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     763.2; E-value: 6.8e-231)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3"
                     /sec_met_domain="DUF4135 (E-value: 9.7e-93, bitscore:
                     305.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.9e-51, bitscore:
                     169.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDFNHYNNAISERIFILSIHEQKAKGNLKGNTSEEQYDYYEKKY
                     LNNATYIKSLLQEYPELKRLLELKNNSTQRAECEIRKSLYAEKEQIQKIFCDGRKFSGT
                     VGIYMAKGDIHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGISCKMV
                     RYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAHGEYP
                     VIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNRGVLI
                     SAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYTECII
                     RGFCRAYMVAMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRERRKA
                     LLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLPCTPY
                     ESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIYSQIR
                     KIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLHDFEE
                     KNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLTGKRV
                     WMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADMEKDLW
                     KKGQETGNGYGWRLKGTDGPLAGMSHGNSGFMMAYAMLYECDHKVEYADKIQLLLRYED
                     SLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLNAADS
                     LFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAKISGT
                     EYLNLAFMNGISGTGMALMEIL"
     CDS             complement(3597..4121)
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIAQKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             4422..4652
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
     CDS             5255..6964
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MYLKSRVKLPDVHGKLTRLRRGDITYIKYEYDRYYDPEKKYTYPQ
                     RATIGKVCPDDDTMMIPNEAFLKYFPDAVLSGMEDRTERSSCLRVGTYAVMHKIVLDYS
                     LDKLLGQFFSERDMALLLDLASYSIVEESNVAQHYPDYAYNHPLYSSGMKIYSDASVSD
                     FFKSITKDKSTGFLNEWNAKRNRRERIYIPYDSTNKNCQAGEIELAEFGHAKTDIGSAI
                     INYSVGYDLKNKEPLFYEAYPGSINDVSQLRTMLGKITGYGYKKIGFILDRGYFSRGNI
                     RYLDECGYSFVIMAKGMSSFISDLILENKGTFENKRSCDMNAYGVYGKTVQRTLFEGDE
                     KKRYIHIYHSISKDADEREHFENALRERTALLMSHQNETVEFGSAYEKYFYLHYDKDGV
                     FLYPEEKTTVTEREISLCGYFVIITSERMTAKEALHLYKSRDVSEKLFASDKSFLGNKS
                     MRSHTNEGVEGRIFTQFIALIIRNKIYTALQEENEKLEKKQNYMTVPAAIRELEKIEMT
                     RQTDNVYRLDHAVTAKQKKILEAFGMNEGNITYRAGEISNTLKKSNIQKERR"
     CDS             6967..7194
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MAREINAELLDTKIEKAQKNLVKAKHRYDAAAATLKDLLDKRDAL
                     RQKKLLDAIAQSGRSYEEIMQYLHSKSEEA"
     CDS             7199..7477
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MLTEYYFAVRYGDIIILLYHEDMMSVWELLFKNSQKEKALKRFLE
                     YCYMIDVKVAFEGLKGEKTKGLKATLKFAKEHDMCMTEAQIQGANNM"
     CDS             7714..8889
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MKSKKVKKILLIALTCVAISASVSAEAAMKSQITIESKNKYEQLK
                     ISESRVYGEYPTGDYKKIMLLPSVSKVEKFCFEDNLNIEEVEWMASVDTVPVFAFSTCP
                     KLKRVILSDNVKKIGQSAFIYCGELTSVKLPQNLQSIDFFAFADCRKLKTLYIPETVTE
                     IGAEAFINCDSLTVHGKKNSYAYYYCKMNGIPFVSEGTASKPETNRPYIKSVDSDIVNK
                     QIYVTIDLSGKVKNADGYQYQIYDGTKVLANKNSANTTCILKKVPTMGFARVRSYTVQN
                     GKKSYSRWSNEMRMPPVKLNKDNIKLIKITGKKKTVTAQFGNLKYSDGFDCVLKNADSG
                     ENIVLKNQKKNTVTFKNIKPGVYYLKAHAYTLLNGIKQFGVWSDNKKVVVK"
     CDS             complement(8970..10682)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MPGTFNGTTLTISATPVDGALIPDKSATNVAGIAIVGSDMYCVKT
                     TGLKTTLLKTTDYMATKATAVKKDLNWFALGLTKIGNYLYMLAEDHKGYGGSTTIVKLD
                     TKGNQLGTYSINEICPKGALGITAADGTNEKFIIMHYADKSNAGTLAFSVVDWKAAEAA
                     STFTVTNSGFGYTTRLQDIYYHTSFGLFILTNNTFSTLQNRILVVDYHLTDDKGKKYTP
                     CSVINVNKTGEYKQYNLESICMKANHLVLASNVITSDGTAEDKFSVLEGITYSGKTYTF
                     ACGFKAGARVPTKVDPNYETTNLGCVSFNGNNTPYFIKQSQDKVAVLGYCKNYMNTSAG
                     VSHFKTFTDGLLGHANGMSCFNGKFFVVAGNNKVVAISSNKEDEEITYTVTPNDNDKSF
                     ALKAINYFYEANTALLLSVVDGTLKLYKCTFENEKNVKATYLCTLVNAGQPTSQDIFYH
                     NKLGLFVGTSNPHTVSGVTTKITTKNTLLHYNLKKLDDSKLLYPDFGFVTDIPAKDAQG
                     RTYNSFELESVALDQNNKLIAVCNVNVKDATHTSGLASTDGFFQYNTLEFITA"
     CDS             11210..11926
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 213.6; E-value:
                     5.3e-65)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MSEMTDAYVKLDKVSKIYGTKEVKIVAVDEISFEIAKGEFVVIVG
                     PSGAGKTTVLNILGGMDQATSGEVLVDGRNIARYNSRQLTGYRRNDIGFVFQFYNLVPN
                     LTALENVELALQICKNPLDAREVLEEVGLKDRLTNFPAQLSGGEQQRVSIARALAKNPK
                     LLLCDEPTGALDYQTGKAILKLLQDMCRERGMTVIVITHNSALTPMADRVIKIKNGKVS
                     RMTMNDHPTPIEEIEW"
ORIGIN
        1 gtagtatcag gaattgccgt agtattgatg attttattta tgtttttttt tgttaaaagt
       61 gttaatatag aaaaaaatat tttggaggtg aaaaatagag ctgtagagca gcaatatcag
      121 gaattagaag atgcatatca aaaatataga tgtattatac atgatcaaaa gcatatgtta
      181 agttttatac aggagtgtat agaaaacaaa gacttaaatg gaattgcggc atatgttgca
      241 gataatcaga aaaagttcag agatgaagaa aaaaagtttt ggacaggtat agatgtactt
      301 gacaaaacaa ttactatgaa aaaaagaaaa atggatgctt tggatataaa ttttgaatta
      361 gatgcttcgg tggatgatac gattataaat actactgatt tggttattat attaagcaat
      421 ttatttgata atgcaataga tgcggctgtt aagagtaagg aaaagaagat ttgtttaaga
      481 ataaagaata taaatgatgt attgatgatg aaaatgtgga atacaagtac gagaattcct
      541 gatgtaaaac gcggaaaatt tgtaacagat aaattagaag cggaaggtca tggatgggga
      601 attgaaagtg taaaaagact tgtaaaaaga tatgatggaa atatcacatt taaatatgat
      661 tctgattttt ttcaggtaat tattatttta agtaaaagtt aaaggagaga taaaaaaatg
      721 acagaagaat ttattggatg tattgaggaa gaacttaagg aaatagaact gttttatgaa
      781 gaaaatggag tagaagtgga agcatatact ttacataacg gatctttttt ttcaatatgt
      841 tgttaaagga aatagaaaag gtatgccaga ctttaatcat tataataatg cgatatcaga
      901 acggattttt atattgagta ttcatgaaca aaaggcgaaa ggcaatctaa aaggaaatac
      961 ttctgaagaa caatatgatt attatgaaaa aaaatatctt aacaatgcaa catatataaa
     1021 atctttactg caggaatatc ccgagttaaa acgtctgctt gaattaaaaa ataactctac
     1081 ccagagagca gaatgtgaaa tcaggaaatc tctttatgca gaaaaagaac agatacaaaa
     1141 aatattctgt gatggaagga agttttccgg gactgtggga atttacatgg cgaaaggcga
     1201 tatacacaga ggaggacgaa gtgtggcgaa ggtagaattg gataatggaa caattctgta
     1261 ctataagcca catagtcttg ataagaatat aaaatatcag gaactttata actatttatg
     1321 tagaaaaaca ggaatttcct gcaagatggt acggtattta tctcatgatt cctatgggtg
     1381 ggaagaaaaa attgagaata tcccctgtaa aaacgaaagt gaggtggagc attattattt
     1441 cagaatgggc atacatctgt ttttaggata tgccctcgga gcaacagatc ttcatggtga
     1501 aaatattatc gcacatggag aatatcctgt gattatcgat atggagacat atccgggata
     1561 tttaaaacaa caatcagaga aagacggaag tagtgtagaa gaaaaaataa acaaaagtac
     1621 agaaataaaa ttggcaaatt cggttataca tacaggaatg cttcctgttc tcacatgggg
     1681 cagaggaaac agaggagttc ttataagtgc aatgggaaca gaggaaaaga taaaaacgcc
     1741 gtttaaactt cctgtggtaa aggatgataa aacatctgat atccacatag aatatgaacc
     1801 tgtggaaatg cagataaagg aatgcattgt aagactaaat gatcaggtta tcaatgcggc
     1861 agattatacg gaatgcatta tcagaggatt ttgcagagcg tacatggtgg caatggcaga
     1921 taagaaagtg gaggtgatgt tgtccggctt ttttgacgga cgttccagag ttgtactgcg
     1981 gcatacccaa cagtatgcaa tgtatcttat ggcttcgttt catccggatt atatgaagtc
     2041 aagagaacgc aggaaagctc ttttgaatgt gattcacaaa gagggggaat cttcttttat
     2101 gaaagagatt catgattatg aaattgacag ccttctggaa atggatatac cctgctttga
     2161 gattgatgcg aacagcagat ctgtttatga tggaaatggc ggagaacata aagagtattt
     2221 gccctgtact ccttatgagt catggcgaat gcatatgaag cagatgagtt actctgatat
     2281 ggaatgtcag tgtgattata tcaggctgtc tatggaaatg ctgaaggcat ctgatggaaa
     2341 gaaaaagatg tttccgacca ggataaaggg atatgacaca gataaagagc gcaaaatata
     2401 cagtcagatc agaaagatag ttcatcgaat ctgcagcaga gcaattatcc gggaacagag
     2461 cgccggctgg gcgggtctgc aattctggga taatggtcac tggaatctca gatcaggtgg
     2521 aatatattta tatgatggaa tatccgggat agtcttgttt cttgcaaaat atcttcatga
     2581 ttttgaagaa aagaatgcaa gtgcagaaga aatttatcat cttgctgttt tgagattgaa
     2641 agcttataca gatgaaatac acaaaaaaca gatttatgat aaaaatcttc tgacaggtat
     2701 tgtaaatgga gaaagctcgg tggtatatac ctatctttat ctgtttaaac ttacaggaaa
     2761 aagagtgtgg atgatttatg cggaaaagca tttcagcatt attgagaggg tatggaaaga
     2821 agattcacaa ctggattatc tgagcggaaa tgccggagct attgtagtgg cagtgatgtt
     2881 atataaagaa accggaaatc tgaaatatta tgaaatagcg gcagatatgg aaaaagattt
     2941 gtggaagaaa ggacaggaaa ccggaaatgg atacggatgg agattaaaag gaacagacgg
     3001 accgctggct ggaatgtctc atggcaacag tggatttatg atggcttatg caatgttgta
     3061 tgaatgtgat cataaagtgg aatatgctga taaaatacag cttttgctga gatatgagga
     3121 ttctctgtac tcagagaaag ccggaaactg gaaggattta cgagagagtt caggggaaag
     3181 cttcatgaat gcatggtgcc atggggcgcc gggaatcctg ctttcacgaa tgaaactgga
     3241 ggagctgttt cctgaggata tgcagattaa aaaagacagg ttaaatgctg cagactcttt
     3301 gttttatgga gaacaggatg aaaaaatttg tctgtgtcat gggatgtccg ggaatttact
     3361 tattatgaag aagtatcttc gaaaatatgg taacaaaaaa atgaaggagc aatatgaggc
     3421 gttatgtgac tgccttttat ttcaactgga tcacccggca aaaatatctg ggacagaata
     3481 tctgaatctg gcttttatga atggcatttc cggtacggga atggcattaa tggaaatttt
     3541 atgaaaacta agggaacacc tgcagactgt aaatttatgg tcagcaggtg tttcttttat
     3601 ttgttttcgg aaatatatct gagaattagt ttcttcttca tccgattgac gtactggcgg
     3661 gacagcttca gtttctgagc aatctgggca tcgcttttat cctgataaaa gtacatggac
     3721 agaatttttc tctggacact gtccgaaggg taagagttga tatatgcggt tacatcataa
     3781 taggtgtcat caaaactgtc gggagcctgt aatgaaacag aacaagaatc aaaatcatct
     3841 ttttcaggtt cggaaagaca actgcggcaa agggaacgat atctgttttc gacagaggtc
     3901 tgcatgtatc tgatacattc accttctgag gatgaagaac ttaaatatgg caatgtcttt
     3961 aacagagtaa gatacaattc ctgtgtggaa tcttcgcgtt ccatgcagtg aatccgggat
     4021 gcatatcctt tcacaagcgg ttccatacgt ttgagaattt cactgtctga atctgggata
     4081 ccattttgat aattttggat aagttctgtc agtgttttca taggtatcta cctccttttt
     4141 aggggaagta gtaagaaaac tgctgatcag aaactaaaaa agaaaaaaat ttgtgagttt
     4201 acaaatggaa gagaaaaaac tctttattaa gtgaggttgc aaatttagat cagcgatagg
     4261 agaagaaata catggtaaaa agagatttgc aaaataattg tagagaatag aaatatgctt
     4321 taaattaaaa cggtaataat aagattagaa aagactttta gtagacaaaa catagaaaaa
     4381 gtttgcataa taaaagaaga ttaaggaagg aggcagaaac catggaaaca acggttatga
     4441 atgtggcagt ttcacaggga atctgggctg tgcttgcggt ttttcttctg atttacattg
     4501 tgaaatcaaa tgaacagagg gatacaaagc aggaagaacg agagaaaaat taccagacgg
     4561 tgattgagag tttaactgag aaatttcaga ttctgaatca ggttcaaagc gatctgaaag
     4621 agattaagga taatcttttt aacaaaaatt aaatagggaa aagaaaaaag ccttttctgc
     4681 aggatatatt tttccagcgg agagggcttc tgtcatttta ggtaagaaaa taggttaatt
     4741 tgagaaaaat atgtttacta aaatggtaga tgaatataag cataacattc gtgtccatta
     4801 gaatactttt aatcccagat ttacagatgt tcgtatagta aatggtatat tatgataata
     4861 aaacctgact tttgggtagt gtaaaataga ttaaaaaaaa tggccgcaat ccaagtgttt
     4921 atgcgagggt gtaaaaattc ttgtgtctat ggaaagtaaa tctttctgat aagaaataga
     4981 tatgtaaaat tttgctgtcg aattaatgat tatgcggctg tcgaatatat ctttgtactt
     5041 acagtattgc catgtaggaa aattatatac atcattttcg atttttttgc atgacaagta
     5101 aggcatcatg attaccttaa cttccaaaaa tgagtagccc taacgaaaat aaaattttaa
     5161 aaaagcccgt atttctgcgg aaattattgc aaaaatacgg gttgtgctgt acaataaatt
     5221 tagggctata taaacctgaa taaaggaggc aaatatgtac ctgaaatcaa gagttaagct
     5281 accggatgtg catggaaaat tgacccgatt aagacgcggg gatatcacat atattaagta
     5341 tgagtatgat cgctattatg atccggagaa aaaatatacc tatccacaga gagcgactat
     5401 aggcaaggta tgtccagatg atgacactat gatgattcct aacgaagcct ttctgaaata
     5461 ctttccagat gcagtcttat cagggatgga agaccggaca gaacgtagca gctgtctgcg
     5521 ggttggtaca tatgctgtaa tgcataaaat agtattggat tattcgttag acaagctgct
     5581 cggacagttc ttctctgagc gggatatggc attattgctt gaccttgcct cttactctat
     5641 tgtagaagaa agcaatgtgg cacagcatta tccggattac gcatacaatc atccactgta
     5701 tagttctggt atgaagatct atagtgatgc gtcggtaagt gatttcttta agagcatcac
     5761 caaggataag agtacaggct ttctgaatga atggaatgca aagagaaatc gaagggagcg
     5821 tatttatatt ccctatgatt ctacgaataa gaactgtcag gccggagaga ttgaactggc
     5881 tgaattcggt catgccaaga cagatatcgg ttcagctatc atcaactatt cggttggata
     5941 tgatcttaag aataaagaac cactctttta tgaagcctat cctggaagta ttaacgacgt
     6001 atcacagctt aggaccatgc ttggtaaaat cactgggtat ggctataaaa aaatcggttt
     6061 cattttggac aggggatatt tcagccgtgg aaatatacgc tatttagacg aatgtggtta
     6121 tagttttgtg atcatggcta aaggcatgtc ttctttcata agtgatttga tcttagagaa
     6181 caaaggaacg ttcgaaaata agcgctcttg tgacatgaat gcctatggtg tgtatggaaa
     6241 aacagtacaa aggactttat ttgaaggcga tgaaaaaaag agatacattc atatttatca
     6301 tagtatttca aaagatgctg atgaacggga gcattttgaa aacgcactga gagagcggac
     6361 agctttgctg atgtcacatc agaatgaaac agtagagttc ggttcagctt acgaaaaata
     6421 cttttatctt cactacgata aagatggcgt gtttttatat ccggaagaaa aaacaactgt
     6481 gacagaacgg gaaatatcat tatgcggata ctttgttatt attacatccg aaaggatgac
     6541 cgcaaaggaa gcactgcatc tttataagag ccgtgatgta tctgagaaac tttttgcctc
     6601 tgataaatca ttccttggaa acaagagcat gcgttcacat acaaacgaag gagttgaggg
     6661 aaggattttt acacaattca tcgcactgat aatccgaaac aaaatttata ctgcattaca
     6721 ggaagagaac gaaaaacttg agaagaaaca gaattatatg acagttccgg cagcaatcag
     6781 ggaacttgag aagattgaaa tgacacgcca gacggataat gtataccggc tggaccatgc
     6841 tgtaacagca aagcagaaaa aaatcttaga ggcttttggg atgaatgaag gaaacattac
     6901 ttatcgagcc ggagagatca gtaatacact taagaaatca aacattcaga aagaaaggcg
     6961 gtaaatatgg cacgtgaaat aaacgcagaa ctactggaca ctaaaattga aaaagcacag
     7021 aagaatctgg tgaaagcaaa gcatcggtat gatgctgcgg cagcaacatt aaaagattta
     7081 ttggataaga gggatgcact tcgccagaaa aagttattgg atgctatagc acagagtgga
     7141 cggagctatg aagaaatcat gcagtacctg cacagtaaat ctgaagaggc gtgatcaaat
     7201 gttaacggaa tactattttg cagtcaggta tggagatatc attattcttc tctatcatga
     7261 agatatgatg tctgtatggg aattattatt taagaacagc cagaaggaaa aggcattgaa
     7321 aagattttta gaatactgct acatgataga tgtaaaagta gcattcgaag gtttgaaagg
     7381 agaaaaaacc aaagggttaa aggcaactct taaatttgcg aaagaacatg atatgtgtat
     7441 gactgaagca cagattcaag gtgccaataa catgtaaatt tccagcccga gatgctttta
     7501 gggctattcc aggctggaaa ttaaggcagc tgctaaacaa aaggctttca gactacaggc
     7561 gaacatatgt tgctgcaaaa ctgtggagat taatttaaat ttgcattttg gttcggggtc
     7621 attagaatac ttttaatacc agaaatacag gatcttttat agttagtgat atattatgat
     7681 aatagatgaa tattattgat tggaggagat tctatgaagt caaagaaagt aaagaaaata
     7741 ttgttgattg ctttaacgtg tgtagcaatt tctgcatctg tctcagcaga agctgctatg
     7801 aaatcacaga taaccattga aagtaaaaat aagtatgaac agttgaaaat ttcagagagc
     7861 cgtgtgtatg gagaataccc aactggagat tataagaaga taatgcttct tccttcggtt
     7921 tctaaagtag aaaaattttg ttttgaagat aatttgaaca tagaagaagt agagtggatg
     7981 gcttcagtag atactgttcc agtttttgcc tttagcacat gtccaaagct taaaagggta
     8041 atactttctg ataatgtgaa aaaaattgga caaagtgcat ttatatactg cggtgaactg
     8101 acgagtgtta aacttcccca aaatcttcaa agtatagatt tttttgcatt tgctgactgt
     8161 cgaaaactga aaacgttata tatacctgaa acagttactg agataggtgc tgaggcgttc
     8221 ataaattgtg attctctaac agttcatgga aagaaaaatt catatgcata ctattactgt
     8281 aagatgaatg gtattccttt tgtaagtgag ggaactgctt caaaaccaga aacaaatcgt
     8341 ccgtatataa aatctgttga ttcagatata gtaaacaaac aaatctatgt tacaattgat
     8401 ttgagcggaa aagtaaagaa tgcagatgga tatcaatatc aaatatatga tggtactaag
     8461 gtattagcta ataaaaattc tgcaaacaca acctgtatat taaaaaaagt gccgactatg
     8521 ggatttgcca gagtccgttc ttatactgtt caaaatggta aaaaaagtta tagcaggtgg
     8581 tctaatgaaa tgcgtatgcc tcctgttaaa ctaaataaag ataatataaa attaataaaa
     8641 attaccggga aaaagaaaac agtaaccgca cagtttggaa atttaaaata cagtgatggg
     8701 tttgattgcg tacttaagaa tgcagattca ggagaaaata ttgtattaaa aaatcaaaag
     8761 aaaaatacag ttacttttaa aaatataaaa ccgggagttt actatttgaa agcgcatgca
     8821 tatacgttgt tgaatggtat taaacagttt ggcgtatggt cagataataa aaaagttgtt
     8881 gttaaataga aaattggaat tataaaaagc aggcgaaaaa ctgcctgctt tttataatgg
     8941 aaatttatgc tgttattgat gtagcgaaat caagctgtaa taaattcaag cgtattatac
     9001 tgaaagaagc cgtcagtgga tgctaaacca ctggtgtggg tagcatcttt gacattgaca
     9061 ttgcacacag cgattaattt attattttga tccagagcca ctgattccag ttcaaaactg
     9121 ttatatgtgc ggccctgagc atctttagca ggaatatctg taacaaatcc gaaatccgga
     9181 tataaaagtt tgctatcatc aagttttttc agattataat gaagcaaggt gttttttgtt
     9241 gtgattttag tcgttactcc acttacagta tgtggattac tggttccgac aaaaagccct
     9301 aatttattgt gatagaaaat atcctgggat gtaggctgac cggcgtttac cagtgtacaa
     9361 agataagtgg cttttacatt tttttcattt tcaaatgtac atttatagag ctttaatgtt
     9421 ccgtcaacaa cggacaataa taaagctgta tttgcctcat aaaaataatt aattgcttta
     9481 agagcaaatg atttatcgtt atcgttggga gttactgtat atgttatttc ctcatcctct
     9541 ttgttactgc tgatagcaac cactttgtta tttcctgcga caacaaagaa ttttccgtta
     9601 aaacagctca taccgttggc atgacctaat aaaccgtcag tgaatgtttt aaagtgagat
     9661 acacctgcgc ttgtattcat ataattttta cagtagccaa gaacagcgac tttatcttga
     9721 ctttgtttta taaaatatgg agtattgttt ccgttaaagg atacacatcc cagattagtt
     9781 gtttcatagt tgggatctac tttggtaggt acacgggctc ctgctttaaa accgcatgca
     9841 aaagtatagg ttttaccgga gtaggtaatg ccttccagca cagagaattt atcttctgcg
     9901 gttccatcag atgttataac attggatgca agcacaaggt gattggcttt catacagatt
     9961 gattcaaggt tgtactgctt atattcacct gttttattta cattgatgac cgaacatgga
    10021 gtgtattttt tacctttatc atcagtaaga tgataatcaa ctaccagaat acggttctga
    10081 agtgttgaaa aagtgttatt tgtcaggata aataatccaa atgaagtgtg atagtaaata
    10141 tcctgaagcc gtgtggtata accaaaacct gagttagtaa ctgtgaatgt acttgctgct
    10201 tcagcagcct tccagtctac aacactgaaa gctaatgtcc cagcattgct cttgtcagcg
    10261 taatgcataa tgataaattt ctcgttagtt ccgtcagcag cagtgatacc taatgcgcct
    10321 tttggacaaa tttcattgat actgtacgta ccgagctgat tgcctttggt atccagtttt
    10381 acgatggttg tagaaccgcc gtaaccttta tggtcttctg caagcatata cagataattt
    10441 ccaattttgg taagtcccag agcgaaccag ttcagatctt tttttacggc agttgctttt
    10501 gttgccatgt agtcagtcgt tttgagtaat gtagttttaa gaccggttgt ctttacgcaa
    10561 tacatatctg accccacaat ggcaattccc gctacatttg ttgcactttt atcgggaatc
    10621 agtgcaccgt ctacgggggt agctgaaata gttaaagttg ttccgttaaa tgttcctggc
    10681 ataatttttg cctcctttaa attttttgaa tttgcaaatt cactatataa agatgctgct
    10741 ttttgtgatt tgtaaaccat aagtgtgtat atgagcatga tttttttctt ttatgcggaa
    10801 atcaggtaag aataaaaata aagattcgag gtcagatgat gtatgtttag tcccactttt
    10861 atattttcgt catcagctta atgtaaaata ataacgggta aagaagatat aagatgttct
    10921 ggtacataca attaagaaga aaggggcatg tgctgtgtat agtcaaaatg atgaaccgcc
    10981 tgagatgatc aggcggtttt gaagtatctg gattttttat gaatatttta tttttaatta
    11041 caggtataat gtgttacaat aaatataacc attaagacta ccaggcaggt cagaatttga
    11101 cctgcctgta aataaatacg gaaataaatc ggggtcaaaa gaatcgttaa taattgtaac
    11161 aaaataaaat taccggtgta gcaaaaataa aattacaggg gaaatgcgga tgagtgagat
    11221 gacagatgca tatgtaaaac tggataaggt ttccaagata tatggaacca aagaagtaaa
    11281 gatcgttgca gtggatgaga tcagctttga gattgccaag ggagagttcg tagtgatcgt
    11341 tggtcccagc ggtgcgggca agacgacagt gctgaacatt cttgggggta tggatcaggc
    11401 taccagcgga gaagttctgg tggatggaag gaatattgcc agatataaca gcaggcagct
    11461 taccggttat cggagaaatg atattggatt tgtattccag ttctataatc tggtgcctaa
    11521 tcttacagcg ctggagaacg tagaactggc attgcagatc tgtaaaaatc cgctggatgc
    11581 cagggaggtt ctggaggaag tgggactgaa ggacagactg accaatttcc cggcacagct
    11641 ttccggtggt gagcagcaga gagtttccat tgccagggca ctggcgaaga atcccaagct
    11701 cttactgtgt gatgagccca caggtgcact ggactaccag actggtaagg caatcttaaa
    11761 gcttttgcag gatatgtgca gggagcgtgg aatgacagtg atcgtcatta cccataactc
    11821 ggcgctgaca cctatggcag accgtgtgat caagatcaag aacggaaagg tttccaggat
    11881 gacgatgaat gaccatccta cacccataga ggagattgaa tggtaggtga tgaatatgaa
    11941 agcaatgcat aaagatttct ggatggagat acgaaaaagt aaggccaggt ttatttccat
    12001 atttatgatc gttgctttgg gagttgcatt cttttccgga atacaggcgt cgtcaccgga
    12061 tatgcgcttc tcaggtgatg cctattatga tgaaaccaat cttatggata tcaaagtaat
    12121 gggaactctg ggactgacgg aggatgatgt agctgccatt aagcaggtgg acggagttga
    12181 gaatgcagag ggcgcctatg gtacagatgt aatgtgtgga gaaggcgaga agcagaaggt
    12241 acttcatgtg gaagctgtgg atcaaaccat gaaccggatc tcagtgacag agggaaaagc
    12301 tccggaaaaa agcggagaga ttttccttga ctgtattttt gctgagagca atggatatca
    12361 ggtgggtgat cagattaccc tgaaagaggg cggagacagc gaactgctga aaaagacaga
    12421 ttacacagtt gtgggtttag gtgagagtcc gctttacata tcctataacc ggggaaactc
    12481 tactcttggt tccggtgagg ttaatggatt tgcctatgtg ctccctgagg attttgacca
    12541 ggaggtttat acacagatct atgtgcaggc tcatggggca caggatctga tcagctatac
    12601 agatgcttat gattccctga tagagcgagt gcaggagcga gtggagggga ttgaggcaga
    12661 acggtgtcag gtcagatatg atgagattgt agaggaagcc aatgacaagc ttgcagatgc
    12721 cagacaggaa cttgaagacg gaaagaagga agctaatgag aagcttgcgg atgccagaca
    12781 ggaactggag gacggcaaaa agaagttaaa agacggcaag aaggaatata aggatggcaa
    12841 gaaaaagctt gcagacgcaa aaaaggaact ggaggacgga aaagcccggc ttgcagatgc
    12901 aaagaaggaa ttagaggatg gcagatccca gcttgccagt gcgaaagagc agcttgccag
    12961 tggcagagca cagatcgcat ctgcaaagga acagctgaat gcaggatggg cggaggtttc
    13021 agagaaccag gcaaagcttg atgatggaaa agcacagctt gaggatggca agaatcagtt
    13081 aagcgctggt gagaagcaga ttgcggatgc aaagacgcag cttacccaga gccagcagga
    13141 acttgacaat ggaaaggcgc agatccagtc aggcagagag cagattgcag caaccagaca
    13201 ggacttaaat gccaaaaagg aaagctgcaa tcagggactt gcccagattg agcagcagga
    13261 ggcccagctt tccgaaggag aggctcagtt agagaatgcc agaagtcagc ttgcagcatt
    13321 acaggcacag tatgaggaag cagcagcttc gggagtatat tcagaggaag acctggcggc
    13381 tctggcagca caggtttccg cttatcagga gcaggtggac agtcaggcag cccagctgga
    13441 agcatccaga aaccagatcg cagcagcaag aagtgaactg gagagtggtt taagccaggt
    13501 ggagagcgga ctggcccagc ttgatgcaaa ggaagcagaa ttga
//
