LOCUS       c00023_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CDHBOPON_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:59:18
            Original ID  :: gnl|Prokka|CDHBOPON_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 37623
            Orig. end    :: 60872
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[47623:50872]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1415..2872
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_36"
                     /sec_met_domain="FGGY_C (E-value: 1.5e-37, bitscore: 122.6,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 1e-79, bitscore: 260.8,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYSLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARSLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(2983..3918)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg23_37"
                     /sec_met_domain="LysR_substrate (E-value: 6.9e-33,
                     bitscore: 107.0, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 5.7e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSPIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4034..5458
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_38"
                     /sec_met_domain="Lyase_1 (E-value: 3.6e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 1.4e-21, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5567..7252)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_39"
                     /sec_met_domain="FTHFS (E-value: 6.8e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_40"
                     /sec_met_domain="OKR_DC_1_C (E-value: 3.8e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 8.5e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEYLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_41"
                     /sec_met_domain="Spermine_synth (E-value: 4.8e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 7.2e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_42"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 6e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 2.8e-35,
                     bitscore: 114.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_43"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.7e-14,
                     bitscore: 47.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRIEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTRASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIQIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_44"
                     /sec_met_domain="PAD_porph (E-value: 8.5e-128, bitscore:
                     419.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGTFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTRED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14489..15367
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_45"
                     /sec_met_domain="CN_hydrolase (E-value: 3.6e-55, bitscore:
                     180.3, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSIAVL
                     DADGKNLGVYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15595..16056
                     /locus_tag="ctg23_46"
                     /transl_table=11
                     /translation="MNRKEFLEILRGQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIILLILIIGVALPFFIILAIILYFLSWLKKRNDQ"
     CDS             16259..20968
                     /locus_tag="ctg23_47"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDTSKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEILVSQIKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGS
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVVQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQIMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGEAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20965..21852
                     /locus_tag="ctg23_48"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGANISYPVVQAADDEYYLKHNFRGEENLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAESK"
     CDS             22044..23135
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_49"
                     /sec_met_domain="Peripla_BP_3 (E-value: 8.4e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 tggaaacttc ggacctgaaa ctcctgaaac tctgatcgca gagagatttg acggaccttg
       61 tatgtatgta gcagcagcag aaggtgacgg tgatatgatc aacggcagag gtgatgctta
      121 ctgtggtatg cttaactgct cctacaactt aaaaatgcgt catctgaaag catatattcc
      181 ggaatatcct gttggaacag cagatgatat tgcaaagatg atcgctgatt tcgtaccggt
      241 tgcacgtgca gtcatcggtg tcagcaatct taagatcatt actttcggac cacgtccaca
      301 ggacttcttc gcatgcaacg cacctattaa aggcctctat gagctgggtg ttgagattga
      361 agagaactca gagcttgatc ttcttgtttc tttcaaagag catgaaaatg atcctcgtat
      421 cccggaagtt tgtgcagata tggcaaaaga gatgggcgaa ggcaaatatt atgctgacct
      481 taatgtgaaa atggcacagt ttgagcttac acttcttgac tgggcagagg ctcataaggg
      541 agcaagaaaa tacgttgcat ttgctgacaa atgttggcct gcattcccgt cacagtttgg
      601 atttgaacct tgctatgtaa atagccgtct ggtttccaga ggaattccgg tatcctgtga
      661 ggttgatatc tacggagcac tcagcgagta catcggactt tgcatttcca atgatgcagt
      721 tacactgctt gatatcaaca actctgttcc acagtatatc tatgatgaag atattaaagg
      781 aaaatacgat tataagctta ctgatacatt tatgggattc cattgtggaa atactcctgc
      841 atgcaagatg tgtgattcca gagctgttaa atatcagctg atccagcaca gacttcttga
      901 gccggcagga tctgaaccag acttcacaag aggaactctt gaaggtgata tcgctgcatc
      961 tgacattaca ttctatcgtt tacagtgcaa ttccgagggc gagctggttt cttatgttgc
     1021 agaaggtgaa gtactggatg tacctacaag atcattcggt ggtatcggta ttttcgcaat
     1081 caaagaaatg ggaagattct accgtcacgt actgatcgag ggcaactatc cgcatcatgg
     1141 agcagttatg tttggacatt acggaaaagc attctatgag gtagtgaaat tccttggact
     1201 ggatgttaag aagattggat acaaccagcc ggcaggcgta agatacccga cagaaaatcc
     1261 atggggttaa tgaaaaatca gtaaaacgga ttattaatgt tcatgtgaag tgaatgaatc
     1321 tgaatacaga ataaataaac tgacactata ttaaaggcat cccggggctt tgctctggga
     1381 tgtattagat tagaaataga aaaggagagc acttatgtat tatattggta ttgaccttgg
     1441 tacttccgct gtaaaactgc ttcttatgga agaatcagga aaaatctgta acatcgtatc
     1501 cagagaatat tctttattct ttccacatcc gggctggtct gagcagaaac cggaagactg
     1561 gtttgcgcag agtatggaag gcatgaaaga gctgacaaag gatatcgaca gagcgcaggt
     1621 agcaggaatt ggttttggcg gccagatgca tggtctggta acacttgaca aggatgataa
     1681 tgtgatccgt cctgcaatcc tctggaatga cggacgtaca ggcgaagaga cagaatatct
     1741 gaatacagtg atcggaaaag acaaactttc acagtataca gcaaatattg ctttcgcagg
     1801 cttcacagca ccgaagatcc tctggatgca gaaaaatgag cctgagaact ttaagaaggt
     1861 agtaaagatt atgcttccta aggattatct ggcatatcgt ctgtccggtt ctttttgtac
     1921 agatgtttct gatgcttccg gtatgcttct tcttgatgta aagaaccgct gctggtcaaa
     1981 agaaatgctg gagatctgtg gaatcacaga agagcagctt ccgaaactgt atgagagctg
     2041 ggaagtagta ggaactctga aacctgagat tgcgaaagaa cttggattca gtgagaatgt
     2101 aaaggttgtt gcaggggcag gtgacaatgc ggcagctgct gtaggaacag gtacagttgg
     2161 cgacggtcag tgtaatattt cccttggaac atccggaact gtgtttattt ccagcaagaa
     2221 ctttggtgtg gacgaaaata acgcacttca ttctttctgt catgcagacg gaagctatca
     2281 tctgatggga tgtatgctca gcgcagcttc ctgtaacaaa tggtgggcag aggagattct
     2341 tcagacaaag gacttcgcag cagagcaggc tccgattcag aagctgggag agaatcatgt
     2401 attcttcctt ccatatctga tgggagagcg ctcacctcat aataatcctg atgcaagagg
     2461 tgtattcttc ggaatgtcca tggacagcac aagagcagac atgacacagg ctgttctgga
     2521 aggtgttgcc tttggtcttc gtgattccct ggaagttgca agaagccttg gaatcaagat
     2581 tgagagaacc aagatttgcg gtggcggagc taagagccca ctgtggaaga agatcattgc
     2641 aaacgttatg aacctgaagg ttgatgttct ggagaacgaa gaaggaccgt ccatgggtgg
     2701 agctatgctg gcagcagtag gctgtggtgc ttacccggat gtagaaacca tcggtaagaa
     2761 atttgccaaa gttgttgata cagtagaacc ggatcctgaa ctggttgcaa aatatgaaga
     2821 gagatatcag aagttcagaa ctctgtatcc ggcgatgaag ccattgttct aatcgaatat
     2881 ctgcctgaca tactggggtt gttgtgctta tttagcacaa caaccccatt ttgacgtaca
     2941 tctgatgatg accaatcacc atagcctatt gattatgaca tatcaggaaa agggcagctt
     3001 caggaattct tccatggctc tgctgatata gcggcctttc ttccagtaaa aaaacacagt
     3061 gcgtttactg ctctgaccgg gcagcttata aaaaacaagt tctgaatttg ttggaactct
     3121 ggagagcaga agatccccga tgaaagtgat acccattccc aaacatgcaa tattataggc
     3181 agtcatctgc tgatccaggc gaaatactac agaaggcgaa aagtgatttt cctgacaaat
     3241 ggtaagtgca cgcttaccgg tatcattatc tgaacgaaga ataataaatg gttcgttctc
     3301 gaatttgttt aatggaacag aaggaatagg agaagaacgg aactgcccgt tccggatttc
     3361 ctcaatagga atctgatatt tctgcagtct ggtatttact gaataatttt tgggaactgc
     3421 aagaagaagt tgttctttct ggtagatata acgttcaaaa atctggttat ccagaataca
     3481 gttatcaatc accagatcta actttccggc ctggagaaac tgggatagct ttgctgtact
     3541 ttcttctaca agagagattt gaacatgggg gaatttttgg gaaaaatcag caataagggg
     3601 aggcagaatc cacgaagaaa aaaagttact gccacctaca ttaagagttc ctgttttgag
     3661 atttcccaga tccagtaggt agttttcgag attattttca atatccatga ctttttcaac
     3721 agcctgtata taatgttttc caacttcagt taactgcaaa ggtttggtac ttcgatcaaa
     3781 aataggatag ccaatacggt tttccacacg ttttacattg gcgcttaaag aaggctgcga
     3841 aatgaaaaga gcagcagcag ctttggaaaa gcttttttcc ttgtagacct catagatgta
     3901 ttccattccc tgaaacatat aaactcctcc gatatataat ttaaacacta tatattttat
     3961 aaaaatatat gtatttgatt atattatagc agagatatat aatgagggca aatacatggg
     4021 agggcgaata actatgaaaa aaacagacta tcgtgtagaa agggattcta ttggtgtaaa
     4081 ggatattccg gaagatgtat attatggagt acaatcctta cgtgcggctg aaaattttca
     4141 cattacgggg ctgaatatgc atccggaaat tattaacagt cttgcataca taaaaaaagc
     4201 agcagcgata accaattgtg aggtggggct tcttgagaag aaaaaagcac aggcgattgt
     4261 ccaggcatgt gatgaaattg tttcaggaaa attccataat gaatttattg tggatcctgt
     4321 tcagggagga gctggcacat ctttaaatat gaatgccaat gaagtaattg caaatcgcgc
     4381 gattgagata ctgggaggaa aaaagggcga ttatacaatt ataaatccta acgatgatgt
     4441 gaattgtgga cagtctacca atgacgttat tcctactgcc ggtaaaatga cttctcttcg
     4501 tttgttgcag aatctgaaaa aacagcttct tcgcctatat gatgctctta atgaaaaagc
     4561 tacagagttt gatcacataa taaaaatggg gcgtacacag atgcaggatg cagtgccgat
     4621 tcgtctggga caggaattta aggcatattc ggtagcaatc atgcgtgata tccacagaat
     4681 ggataaagca atggatgaaa tgcggactct taatatggga ggcactgcta ttggaacggg
     4741 aattaatgca gatgaaggtt atctgagaag aattgttcca aatcttactg aaatctcagg
     4801 aatggacttt atacaggcct ttgatttgat tgattccact cagaatctgg atccatttgt
     4861 agctgtttcc ggtgctgtga aagcatgtgc ggtaactctt tccaaaatgt caaatgatct
     4921 ccgtctgatg tcctccggtc cacgtactgg ttttggagag atcaatcttc cagcaaaaca
     4981 gaatggttcc tctattatgc caggtaaagt taatccggtt attcctgaag tagtgaatca
     5041 ggttgctttt aatattattg gtaatgatgt taccattacc atggctgcag aggctggtca
     5101 gctggaatta aatgcgtttg agccgattat tttctattgc atgttccagt ctatcgatac
     5161 tcttggctat gcagtccaga cattggtgga taattgtatt gtaggaatta cggcaaatga
     5221 agaaagatgc cgttatctgg tagaaaacag tgtaggtatt atcactgcaa tcagccccca
     5281 tcttggatat cagaaggctg cggatattgc aaaaaaggca attaagacag gcgaatctgt
     5341 aagaagtctg attctgaaag aaaagcttat ggacgaggat gaacttaatc gcattctgga
     5401 tccgatccat atgacggaac ctggtatttc cggaaaagat tatcttataa aaaaataaag
     5461 aaaaaaacag gcgggaaaat tttcccgcct gtaaaatcgt ctggacacat atcatatata
     5521 aatatgattt ttatattttt gaattattcg attgatttca actggattag aacagacctg
     5581 tgatcttacc tgtctcgtct acgtcgattc tctcagcagc cggaacttta ggaagacctg
     5641 gcattgtcat gatctcgcct gtaagagcta cgatgaatcc tgcaccagcg gaaatcttca
     5701 ggttacgtac tgtaacttcg aagtcagtag gagcacccag tttagtctgg tcatctgtta
     5761 agctgtactg tgtcttagct acacagatcg ggcagttgcc aaagccaaga gcttctaact
     5821 gtttcgcctg tttctgagcg ttagctgtca gaactacttt cttaccgcca tatactttct
     5881 gaacgatctg gttcagtttg tcttcgatag aaccttccag ttcatatgca taggagaagt
     5941 cgtttggttc ttcaacaaga cggataactt cttctgcaag tttgattccg ccttcgccgc
     6001 cttttgccca cacttcagaa agagcaacgt taacgcccag ttctttacat ttagcttcta
     6061 caaagtcaag ctctgctttt gtatctgtag ggaatgcgtt gatagcaaca acacatggaa
     6121 gtttgtatac gtttttgatg ttggaaacgt gttttaacag gttcgggata cctttttcaa
     6181 gagcttccag gttttcattg ttaaggtcag ctttagcaac accgccgttg tatttcaggg
     6241 cacgtactgt agctacgatt acaactgcgc ttggttttaa accagccata cggcatttga
     6301 tatcaaggaa tttctcagca ccaaggtcag caccgaaacc agcttctgtg attgcataat
     6361 cagcaagctt catagccatc tttgtagctg ttacagagtt acatccatga gcgatgtttg
     6421 cgaatggtcc gccatgtacg attgcaggaa cgtgttccag agtctgtaca aggtttggtt
     6481 tcagagcatc ttttaacagg gctgtcatag cgccttctgc gtgaaggtca cctgctgtta
     6541 caggtttctg ctcggaaact tttccgtatg tatatccgat gatgatcttg gataatcttt
     6601 ctttcaggtc tttgatgtcg cttgcaagac agagaactgc catgatttca gatgcaactg
     6661 tgatgtcgta tccgtcttca cgaggcatac cgtttgtctt tccaccaaga ccatctacta
     6721 cgttacgaag ctgacggtcg ttcatatcta cacatcttct ccatgtgatc ttacgtgggt
     6781 cgatgtttaa tgcattgccc tggaagatat ggttatcgat catagctgcc agtaagttgt
     6841 tagctgcgcc aatggcatgg aagtcacctg tgaagtgaag gttaatatct tccataggaa
     6901 caacctgtgc atatccgccg cctgctgcac caccttttac accgaatacc ggtcctaagg
     6961 atggctcacg aagagctacc ataacactct tgccaagtct ctgcatacca tctgcaagac
     7021 ctacagtagt agtagtttta ccttctcctg ctggagttgg gttgatagct gtaacgagga
     7081 ttaattttcc atccttctta tcactttctt tcagaagatt gtagtcgatt tttgctttgt
     7141 attttccgta ctgctccaga tatttgtcgt caatacctgc tttctctgcg atctgagtaa
     7201 ttggaagcat ttcgcattcc tgtgcaattt caatgtctga tttgaatccc ataattgttt
     7261 ttctcctttc gtttccgcat aacatgaaaa acttctgttg ctgttcactc cgcgatcagc
     7321 aacaattatt aattgaaaga agtattggcc ggtctgcctg gtattcctga tttctgccct
     7381 gaaagttata aaaaaaggcc agtatctgaa tatttcaaat actgcccaga cggtcggctc
     7441 ccacaaacct ccgactccac gtggtttgca ctccactctt tccgtcagta ctcgaaggtt
     7501 ctttcaattg atgaatacaa tatatcattt tgagaaaaaa atgtcaagaa aattttgttg
     7561 aaacgtcaaa aaatgtgagt aaactggata aaagttgtgc aaattgataa gagaagagaa
     7621 tcgtaatccc tggtcatgaa agaaaatacg ttttctcaag gaaagaaatt gttaaaaaat
     7681 aaacacagtt ttccctgata aatgaagaaa atataaaaag cgggtaaagc tagagcgtgt
     7741 ctgaaaaatc attcccgcaa tctgtacgcc cccactttgc gggatatttc actcgaattc
     7801 agttgccgta gcccgctacg gcgccctcat ccgggcaaaa tatcccacaa attgtgacgc
     7861 acatcttgca gaaagccttt ttcagacacg ctctagtgca aaatatggaa aatggaattg
     7921 acaacagttc agaagatatg ttattctcat ctttagtatg aaaagacact atcgttttca
     7981 tgcaaatatt tgctcacatt cagagacagt ttctgaatgt taagccatac ggacaggcgg
     8041 ggcagttgcc gggtgggaga caccacatta ttgattgagt tagaagctca aattttataa
     8101 gttgattact ttataataat cagtgcgtaa gcacacatca tcttgtgaaa cggtcaataa
     8161 gagcatagca tatatttgcc agcgattgaa gacgacagca gtcatgaata tttcagaata
     8221 cgggaacagg cacaggatac agacggattt atacgggaaa tccggtcagt atataaagag
     8281 acagagcctg agaaattcta tagatcatga gagaagcaga tggtgaatga acttatctgc
     8341 ttcttttttt gtgcagatat agcaaatata aaggatatgg ttggagataa acgctttgcg
     8401 aggatgtgtc tcacatgcgt tcgacttgaa tatatagaga aataattgaa tcattgtgcc
     8461 ggtttgaggc agtatacaat tgctgaatga tagaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcgcagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc acccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcattcct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctgtctgtct gcaaggcagg ggataagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agccaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agcgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc tatttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccatcgg agacaggctt caggatattg
     9661 agagactggt aggggcattg gctgatattg aacgtctgta caagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaata tcttcaggtt ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgataaaga tgaatttatt tatgatgaga tggttacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaaggtagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctacgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taaggaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgcc tatgccttga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgatttccc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggagatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgccct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtataga agatatagag gaactggatc ggatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagaagtgt gtactagagc
    12481 cagtctggga ctccgtatta atccggaatg ttccactcag ggggatcatg caatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatt gacggactgc attttcatac gctctgcgaa cagaatgcgg atgatctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attttggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt gatcggagat tattcctttg acagagagat
    13081 ccagatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttgggaa tgtttccggt gtgactttgc tggaatgcga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc cgtctgtgga gttgactggc
    13621 agtttaatgc ctggggaggt acctttgatg gactttaccg gaactgggag aaggacgaca
    13681 gggtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgcttgaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccgg gaagatgtgg atggttttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggccgcca gttacgtgaa tttttatatt tccaatggag
    14221 gaattattct tcctcagttt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc agagagaagg atttatccca ttgatgccag agccatcatt gttggcggtg
    14341 gaaatattca ctgtatcacc cagcagattc ccggaaaaaa tatctgaccc tgatgcagaa
    14401 aactttgaga gtcatgtgtt tgagggttat tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tgcccatgca gaggaactgg tgcgtcaggc
    14581 agcagcaaag ggagctgaga ttgttcttct tccggagctt ttcgaacggc cctatttctg
    14641 ccaggagcgc agatatgagt attatgaata tgcgcagact gcagaggaaa accctgcagt
    14701 gcgtcatttc agcagggtag cggcagagct ggggattgtg atcccggtca gcttttatga
    14761 aaaagaggtc aataatacct ataacagcat tgcggttctg gatgcagatg ggaagaatct
    14821 tggcgtttac cggaaaacac atattccgga tgaccattat tatcaggaaa aattctattt
    14881 cacaccggga gataccggct ttaaggtttt tgataccaga tttggaacca ttggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac ggcaagatgt atggcactgc agggagcaga
    15001 gcttctcttt tatcccactg ccatcggaag tgaacccatc ctggaatgcg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaac ctgatccctg tgatcgctgc
    15121 caacagaatc ggtgaggaaa cagtagagcc atgtccggaa aacggaatgc agaaatctgc
    15181 tcttaatttt tacggctctt cttttatcac agacaacaca ggtgctctct gtgcagaact
    15241 gcccggaggg gaagaggggg tgcttgtaag cacttttgac ctggatgcat taaaggcaga
    15301 cagactgaac tggggacttt tcagagaccg cagacctgaa atgtatgcaa aaattgtcgg
    15361 gaaatgacat acaagccaaa attccattgc cgcaggcaat ctggaatgaa ttttggctca
    15421 gttactgaga acggagtgaa cagtaactga gtttataaga atttcataaa aagtttatga
    15481 ttatattagt tgctacctgc ggtatatatg gtaaaataag agtacgaacg ttactgataa
    15541 cggagcgagc agtagagttt tgatatgtat ttctggcaaa atggagtgta gaagatgaac
    15601 agaaaagaat ttttggaaat cctgagaggc cagcttgccg ggcagatgca ggagggcaaa
    15661 gcagcagcac atatcaggta ttatgaagat tatatacagt ctcaggtacg tggcggacgt
    15721 tcagagcagg aggtactgca ggaactggga gatccacatc tgatagcaaa aactctgatc
    15781 gatacagatg atggaagtac acaggaagat tacggagagt attcttctta cggaagcagt
    15841 tatggcaatg agacagagct tcctcatcag caggagaaaa gatggaaaaa agtaatcgat
    15901 ctttctacct ggcatggcag ggctgttgtt attgcagcag cggctgttat aattatttta
    15961 ctgatactga taatcggagt tgcgcttccg ttttttataa ttcttgcaat tattctttat
    16021 tttctttcat ggctgaagaa aagaaatgat caatgaaaat ctatgcaggg tttcagaaaa
    16081 gaaaccctgc gcagaatctt aaaatcttaa gtgtaaacgt tcttgtttca cgatattaat
    16141 tccccttgaa tatttataat catacaatct caacttattt ctattcttta atcctgccag
    16201 gtgcagggaa aaatcccaca ttcattttta tattttttgt tcggaaagga gacggaaaat
    16261 gaaacacaat ttcaaactga aagaacgcct tggagctttg ctgcttgcaa tgctttttat
    16321 tctgcaggca attctggggc ttgtgcctgt ctgcgtaact caggcggcac cgttaactgt
    16381 agaaacatgg gacagtgaca aggtggtaga ttatggttat cgctttaaca tgaagtttca
    16441 gcccggaatt accacatatg aatcttttgg gtgtgataat ctggacaggg aagctttttc
    16501 agacaatgga aaaagcgaac gtgatacaga gtgtgttcgt gtaggagcgg actataaagc
    16561 cggaagcgca gggatgcgtt ataacaatgt aggaaaagat ggaaatggaa atattgttga
    16621 tgtcagactc attcttgtgg gagtagagaa tgcagaaccc cgttatgatc tgcgcactgc
    16681 agaatcgatt gttcagaata aaggcggagc tacgtttgca tggaaagata atgaagctta
    16741 tccaatggtt ggcttttcca aaaacagtat cggtgtattt atttattctg taggatacgc
    16801 aaaggttaag tttcagtttc tgaagcatgg aacagaagaa acactgccga tcagtggcca
    16861 tggaaccata cgtgatattg atgcgggaca gggagtccgt attccgtcag acagcagtct
    16921 ggataatgca tatgttctga aaaacaatga ttatctgacg gtagatggaa attctgtaag
    16981 ctcacccctt ggttccgttg agccggatga tccgagagga tggctgaatc ttttttataa
    17041 tacagataat tttacggtag aattctgtca tcagttcaga ctggataaat gggataaaag
    17101 tcgtgaagat gccattgcaa aagccggttc tcaggaaaga tgggcagaga ttacaagaaa
    17161 taaatatctg gatccatcag gcaacagtta ttgtccgaac tttaaaggac agaaatactg
    17221 taaagcatat gcatattttg attttacatc ctattgtttc ggcgatgttg agatgaaaaa
    17281 agcacctgag aaacgtgtgg gagaggcaaa ctgtacatgg gaacaggcag ctgccgcatc
    17341 aaaagaaaaa ccttttggca ttcgtcaggg acaggaattt cagtatatga tccgggcaga
    17401 ggtgacaccc aatagactga aatcctttgt ggtacaggat atacttgagg attgtcttac
    17461 tatagaggat acatcaaaag tcagtattgt gaatgatgca gggcagacag tgacagactg
    17521 gtttgatgtt gctgttgaag gacagaaagt gacctgcagg gccaaagcag agagccttca
    17581 ggatgaagca tttacagata atcagactta cacatttact ttaaaagtac gccagagacc
    17641 ggaatcagaa attaacattt caaaatacct tgcagaggat ggatacagta ttcttgtacc
    17701 aaaccatgca tccatgagtt atgaacgtac aaacggaagc ggagatacaa tggatacgga
    17761 aacagtgtgg gtaaagggtg tgattccacc ggaactggaa gtaaagaaaa atacttctca
    17821 gtatgaatgg aaaacgggag atatcataga ttatgagatt ctggtttctc agataaaaca
    17881 ggatgtaaaa gcagtaaatg ttgttattac agacgagctt ccatcatgtc tgcagcttct
    17941 ggaagggcag tatgctgtag agacaagtca gggaggtgag aactgtacgc ttaccggaca
    18001 gggagaaaat ggatggaaag cagagtgtcc gtccctgaag tatggggaga cgatcacaat
    18061 ccgttttaaa tgtcaggcat ctgcggattc caatggacag gaatgggaaa atattgtgac
    18121 tgcaacagcg gataatctga tcaatcctga gacgggagaa caggaatcca gaaaggatat
    18181 ggcagaagta tggccgaaca gtccacagct tgaaattgat aaaacagcag acaaatatga
    18241 atggcaggca ggagagcagg tagcttaccg gatcgtggtg aataatgtaa cggcaggaac
    18301 aatcgcaaaa gatgtaacta ttactgatat tggtctgccg cagggactgg ttctggcagg
    18361 tggtgcacag agcatggaag tactgggagt tcagcaacag gtaaactatc ccgtaccgga
    18421 taagaaaaca ggacaggcat atgaagcgag acctgtggat tctcagttga atgcagatga
    18481 gaacggattt tccttttatt gttcttatgt gccatacagt cagcctgtaa cgattatttt
    18541 ccattgtatc gcacaggaag aggcaaatgg acacgaaagc gtaaatgcag caactgtaaa
    18601 agctgctaat acagatgaga gatctgatga tgcagaagta tatgtaaatt caggagaatt
    18661 ctggattgag aaatctgcag atcattatga atggcaggtc ggagaacagg tacagtacaa
    18721 tgtggtggtg gagaataaaa aagcaggtac agtggcccgg aacgtaactg tctgggatac
    18781 cggtatgcca gcaggacttg cactttcatc ggcagaggat gtatcggtaa gcggaatccc
    18841 acagaatatt acgcagctga cagcagggag caaagatgtt ttgaaccagc tcaatccgga
    18901 attttataat gagacatcag agaaaccagt gaattatgaa tttcttcagg agggaagcgg
    18961 atggagactg aacatttcag atcttccggc aaatactccg gttatgattt ctttcctttg
    19021 cacagttacg gaagcggcaa atggaatgga aagcattaat gttgccaatg tgcaggcgca
    19081 gaatgcccct gtttcgcagg atgacgcaga agtgtatgta aatacagcag ttctttctat
    19141 tgagaaaagt tttcagaatc catatctggc agccggggac ggacgtgcgg aaaatgaatt
    19201 tcgggtagga gaacaggtga attatcaggt tacggttaat aatcttcaga agggatctat
    19261 cgcaagaaat cttgtgatca gtgatctttc ccttcctgaa gggctggctc tggacggagc
    19321 tgaagatgct gttactgtaa gcggtgttcc ggctgttgtt cagaatccgg tggcaggaac
    19381 tgatgatgca ggaaatcagc tgaatccgga aaattataaa gaaacagtgg aaaaaccggt
    19441 cagctgtcag gttacacgcc agggaaccgg atggatcgtg acgatttcag atcttccgta
    19501 tcagacacct gtgactgtta atttccgctg tactgcgcag gaaagcgtaa atgggatgga
    19561 gattgtaaat acagcacagg cgtatgcaga taatgcacag aaagtaaagg actcctcaaa
    19621 aatctgggtg aactcgcctg ttcttaaagt agagaagacg acggacaaac cattttacaa
    19681 atatggtgat attattacat accgcattgt cctgacacag gagcagaccg gatgtgtggc
    19741 gcgtaatgtt actttgcagg atgtgatcga tactcaggga gtacgtcttc tgaaggattc
    19801 ggtgattctg atggatgaga aaggaaatgt agcagatgct gatgtacaga tcaatgatga
    19861 taatactttc ctgatgtcaa caggcaggac actggtcagg gatagcagat atagtatctg
    19921 cgataatgat aaaggcggtc tttttgagca gataatgtat aatcctctgg actgtcagga
    19981 acagaaaagt atgatcgtgg aatatcaggc agcggtgatt gatgcagccc tggcaggaca
    20041 gaaagtgcac aatactgcag ttgcagacag cagtgaaaag atacctgcaa ccggggaagc
    20101 agagacagag gtacacagtc cgattctgga aattgtgaag gaatcagata agaaagagta
    20161 tgcgtccggt gagaaaggat actataaatt gacagtaaga caactgcgtg aggatgtcac
    20221 agatcagaat attgttatcg aagataaact ggaaacccaa ggggcttcca ttgtaaaaga
    20281 cagcattttt gtgaagaaaa acggtataga actgaaagat gccaaaatag aggcagatga
    20341 tacaggattt gtaattcaga caggagcatc gttgtcagat atggataaaa ttgaagtctg
    20401 ctatgaaatg gtatttaaaa cagaaagcac agagcctgaa aaaattgtaa acacagcgaa
    20461 agcaagaggt gatatttcac cggaaattac tgcacagcag gaggcatatg tgaaagcaaa
    20521 agcagaaccg actgccacac caacaccgtc tgcaacaccg aaaccaacag aaacaccaaa
    20581 gccgacagag acaccaaaac ctacagaagt accgaaaccg acggagcagc caaaagccac
    20641 accaacacca tctgtaccgg gaacctgccc gaaaatgact cctgtaccga cgaaagcacc
    20701 gttagcatct tacaatggtg gaaataatgg aggcacgact tccggaagcg gaggcagcag
    20761 ttacgcaaat tcgggtggat attccggtgg atacggaagc tatcagggtg gttccatggc
    20821 aggaagttct aaaacaggag atgtcagacc gtttaaaatg atggctgttc ttggacttat
    20881 cggaatggga ctgctgacag gaggtgtggt gatctacaga agaactgttt ccgggaaaag
    20941 aaatataaag ggtatgccgc ggaaatgaaa aaactcagaa catttgcagt aagtatgatc
    21001 atagcagcaa ttgggcttct tatatattgt gccggcttct atataaaaag ttatgaacag
    21061 aatcttgcag caaggcagga atatgcagag ctttcccaaa tggcaggggt gaagaacaga
    21121 gaaggtgccg gattattggc agatggcaaa aaaactgatg aagacagtag tacaaaaaac
    21181 agtgaaaaaa aacgcaggaa aaaacagaga agatcttctg aatcaaaaaa caaaaactgt
    21241 acagatgaaa tcagggaatc cttcgggatt tcctgggaaa atttaagaaa gatcaactct
    21301 cagacggttg cctggattac tgtcccggga gccaatattt cttatcctgt agttcaggcg
    21361 gcagatgatg aatattacct gaaacataat ttcagaggag aggaaaatct gtttggatgt
    21421 atttttctgg aacatgacat aaaaaagaat tttacagatt cccacagtat tctttacggg
    21481 cataatatag aaggtaatat gatgtttgca aatctgaacc gttatgaaca gcctgaattt
    21541 ctgaaaaaat gtcctgaaat tgagatcaca acaccaaaaa gaaagtttct gtacaaaatt
    21601 ttttctgtgg aacaggcatc ttcccaaagc ccggcatttg aatatggata caagttatcc
    21661 agtcctgcat acaggagaca attatctata ttgaaaaata attccatgta tgacacagga
    21721 gtagagcctg atgaaaggga gagaatggtg actctgatca cctgtaattc acgtctggat
    21781 aaagaaatac gtatggcggt acatgggatt tgccatgaat gttatggtat agaaaaagct
    21841 gagtcgaagt gatgttgaaa tcaatcggat attggtaact ttcgtaaagg atgaactgtt
    21901 actgttcaca catcactatc cctcgaggtg ttttgggaaa aactaatgaa aaatctctcg
    21961 atattttgta taatttatgc ataaaaaaca acttgttcgt acgtgcgtac aagttgtatc
    22021 ctaaatacag gagggaagaa gacatgacag ataatggaaa gccgaaatat ttctcactga
    22081 tggaacagct cagaagtgat attatgtcag gagctatccg accgggagag aagcttcctt
    22141 cagaaaacga gctttcacag aaatattccc tgagtagaca tacagttcgt aaagcactgg
    22201 gaatcctgga gcaggacgga tatgtagagg catttcacgg aagaggtact tattgctctg
    22261 agaatatgcg ccatataaag aattcaaaga atattgcggt agtgaccaca tatatttctg
    22321 attatatttt tccgagactg atacagggaa tggataatgt cctttcagaa agcggttaca
    22381 gtattatcct gaaaaacaca gcaaacagca gacagaaaga ggccagatgt ctggaggaac
    22441 ttctgaagaa agatattgat ggactgatca ttgaaccaag caaaagtgag atgatctgta
    22501 aacacagaaa tctttatcag aatctggata aatttgaaat tccgtatgtg tttattcagg
    22561 gaatctattc agaaatgagg gataaacctc atattcttat ggatgatgca cagggaggct
    22621 atcttgtaac aaaatatctg ctggaactgg gacataaaaa gatcaagggt ttctttaagg
    22681 cagacgatat gcagggactg gagcgccaca agggatatgt gaaggcctta caggagtcag
    22741 ggattgccta tgatcctgat gatgttgtct ggtttcatac agaggacagg aaagtaaaac
    22801 ctgcactgat ggcaaaagaa atggtacaga gcggacagct tccggatgga atcgtttgtt
    22861 acaatgatca gattgctgtt caggttatgg aagaactgga gaaaatggga gtcaggatac
    22921 cggatgatat ttccattacc ggttatgaca attcactgta tgctcagcga ggaagcggaa
    22981 tcacaacgat agctcatccg caggaaaagc tgggagaaat ggcagcagag cttatacttg
    23041 agaagatcaa cggagttcct gaagaagaaa gtaaggttga aagactgatt tatccggaac
    23101 tgatcatacg gggatcatgc agaaaaatat tgtaaacaaa tgaaataaat aaaaataaat
    23161 ccgggaggaa ttttatcatg aaaacaggaa gaaactataa gttctggttt tgtacaggtt
    23221 cacaggatct ttacggagat gagtgctta
//
