LOCUS       c00033_gnlPro..        13471 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ALLFPFAG_36.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 15:48:34
            Original ID  :: gnl|Prokka|ALLFPFAG_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 129326
            Orig. end    :: 142797
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13471
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[139326:142554]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..13471
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13471
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(756..2489)
                     /locus_tag="ctg33_113"
                     /transl_table=11
                     /translation="MALDGIFLRHIKSEIEKEALGARVSQIYQPNREELVFGLRTFSGN
                     KKLLLSARANSPRVNFCSSTPENPAQPPMFCMLLRKRIGGGKLVGLRQNGCDRVLMLDF
                     ECVNELGDTVMITVVCEIMGMYSNIIIVDSNGVIIDSLKRVDLTMSSKRLVLPNIKYEL
                     PESQNKLNLLKCSALDVCTAVKNLDTEMPLNKALLRTIEGVSPIVCREIEYKIMEGATN
                     RIEGVLFDRLSVEIEKLKNVCSDCSGKPVVVYREDGKPMDFCFMNVEQYGDFAKVESKE
                     SFSDLLDGFYEARDSRDRMRVKSQSLTKLLNNTLERLARKIAKQKSELERCADREHLRI
                     CGDLLQANIYRIERGAEYVDVENFYDENNAILRIKLNPAISPSANAQKYYKDYRKAKNA
                     EIMLKEQLEKGREELDYINSVLDTVDRAENEKDLAQIREELTEQGYLKVQKGKKPRQTT
                     LPPLEFESSDGFKILVGRNNRQNDKLTLKTASKNDMWLHTKNIHGSHVIVVSDGKEISD
                     TAIYEAARLAAYHSKARNSSQVPVDCTFVRYVSKPNGSKPGMVIYVNNKTLYVKPSQTV
                     E"
     CDS             complement(2504..2989)
                     /locus_tag="ctg33_114"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTEAIAEYAKRLTAFCKFNIIELSEERIK
                     SNIPNRSQIDEVIFSEGKRIMQKISPSDYVVAMCIEGKSMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSRMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             complement(3011..3799)
                     /locus_tag="ctg33_115"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSASEGVLIDAGRSCKQIENAMLANGL
                     DMGSIGAIFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRIDTPHDAAESCCYRVTAPDGKSALIATDMGVMLPDVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSVSTTKAIIF"
     CDS             complement(3922..5214)
                     /locus_tag="ctg33_116"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDSLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     IRMGAQISVEGRLAIIEGGVPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRALGADIKKVYFTGDNEQELGA"
     CDS             5897..6613
                     /locus_tag="ctg33_117"
                     /transl_table=11
                     /translation="MSETAKEPKKISKRSSEEKIEIIVAIFLGITALATAWASWIGSLH
                     GGNQATNYTKSNNLSSEGNSMWNEASQNLMQDMITWNDINEANLNYQYAESKNDKAEME
                     KYQYQIDQLMSDNCTEEFLEAINWAMDQKENVTPFMKDGYTESYFAEAKATIEESDKLL
                     EQGKKDNANGDAFGLVSVIYSVVLFMLGIVGTFKNLPNRRIVLGVAVAGFILATIYMFT
                     IPMPTGFNILSYFGMA"
     CDS             6818..7135
                     /locus_tag="ctg33_118"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALNMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             7148..9700
                     /locus_tag="ctg33_119"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETDGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKIAETDG
                     FEDVIFNFATKLLNFKSEKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLN
                     CAHCAGKIEAKIAETDGFEDVSFNFATKLLNFKSEKQNPVSEIQAICDSIEDGVTVVDK
                     TPKNDVTTKAEPEITKKKINRDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFV
                     ATILSGYKVFIKGAKNILKLRIDETTLMSVAVIAAFCLGDFVEAAMVTILFSIGEIFED
                     RAVDASRRDIEKLANIRPDTATIIVDGAEQVVPAESVEIGSIIEVKPYERVPLDGIIIK
                     GKTTLDTSALTGESLPVDAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDA
                     AAQKGNSEKLISRFASVYTPVVVLIAVAIAVIPPLCGLGSFSEWLYRALVCLVASCPCA
                     IVISVPLSYYSGIGAASEVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTV
                     GSYSADEVLAIAAASEKYSAHPIASAIREKANGLELPELSDYSESAGHGTSAVYNGKTI
                     QCGGSKILSDEQKKIANKDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKALGVKNT
                     VMLTGDRQQPAENVKNELGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVL
                     SASDCGIAMGFGSEAAIEASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKAL
                     VIILAAFGLAQIWMSVIADTGVSVVCVLIAARLLKKKY"
     CDS             10001..11623
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_120"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-42, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNEEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             11636..12127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_121"
                     /sec_met_domain="ALS_ss_C (E-value: 1.6e-29, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             12188..13228
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_122"
                     /sec_met_domain="IlvN (E-value: 7.6e-83, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 5.3e-60, bitscore: 194.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYEGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKIAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
ORIGIN
        1 ctttaaatat gcagatgatt ttcttgcggt aaaatactct tccgcaccga attatgtcaa
       61 cacagctgtt gccgcaattc acgaaatgac ttttcaggtt ggtctgcccc agtttgacga
      121 tgacggcatt atgaaaaagg gcgttatcgt aaggcatctg attttgcctg cccacacaaa
      181 gaacagtctt gaagtgcttg atattgtaaa acgcagattc ggcgatcagg ttttgttaag
      241 tcttatgtgt cagtacattc ctatgggcaa ggtcagcgac agggagtttt caagaattaa
      301 ccgtaaaatc acacgcagag aatatgacaa ggtaaagctt gaaatgatgc gactgggaat
      361 tgacggcttt acacaggagc tttcttccgc agatgaaagc tatgtccccg aatgggattt
      421 tgaaggataa ttttttgatt aatggaactc ttgtagcggc gaaccgtgtt cgccaatcat
      481 ttcgtatgta aatacgaaat gagcaaaaaa caagctttcc acaataatcc aattaatttt
      541 attggaacat atgtatcctg tcggaacgat tttacaatcg ttccgattgg cgaacgaggt
      601 tcgccgctac gaatgaatac acaattttct tcttattaaa atctatgtgt ttgaacatat
      661 aatatcatca gggcgggcgt ccaatgaacg cccctaccga tttattttca aaaacaaaac
      721 ggtcaagaaa cattttttag tttctcgacc gttttttatt caaccgtttg tgacggtttt
      781 acatacaggg ttttgttgtt gacataaatc accatacccg gttttgagcc gtttggcttt
      841 gacacatagc gaacgaatgt gcagtcaacg ggaacctgac tgctgtttct cgctttactg
      901 tgatatgccg caagccgtgc cgcctcatag attgccgtgt cggaaatctc tttgccgtcc
      961 gaaacaacaa ttacatgaga accgtgaatg ttctttgtgt gcagccacat atcgttcttt
     1021 gacgctgttt tcaaagtcag cttatcattc tggcggttgt ttcttccgac aaggatttta
     1081 aaaccgtcgc ttgattcaaa ttcgagcggc ggcaaagttg tctgacgggg ctttttgccc
     1141 ttttgaacct tgagatagcc ctgctcggta agttcctcac gaatttgcgc aaggtctttt
     1201 tcattttccg cacggtcaac cgtatcgaga accgagttaa tataatcaag ctcttccctg
     1261 cccttttcaa gctgttcttt gagcataatt tcggcatttt tagccttgcg gtaatccttg
     1321 taatacttct gagcatttgc cgaaggtgag attgccggat taagctttat gcgtaaaatt
     1381 gcgttgttct catcgtaaaa gttttcaaca tcaacatact ccgcaccacg ctcaatgcga
     1441 tagatgtttg cctgtaaaag gtcaccgcat atgcgaagat gctcacggtc tgcacagcgt
     1501 tcaagctcac tcttctgctt tgcaattttt cgtgcaagcc tttcaagggt gttgttcaaa
     1561 agctttgtaa ggctttgtga tttcaccctc attctgtcac gactgtcacg agcctcatag
     1621 aatccgtcaa gcaaatctga gaagctttcc ttactctcaa cctttgcaaa atcgccgtac
     1681 tgctcaacat tcataaagca gaagtccata ggcttgccgt cctcacgata aaccacaaca
     1741 ggcttgcctg aacaatcgct gcaaacattt ttcagctttt cgatttcaac tgagagtcgg
     1801 tcaaaaagca caccctcaat tctgtttgtt gcgccctcca taatcttata ttcaatctca
     1861 cggcatacaa tcggagaaac gccctcaatt gtccttaaca gcgccttgtt aagcggcatt
     1921 tccgtgtcaa gattttttac ggctgtacac acatcaagcg ccgaacattt aagcagattc
     1981 agcttgttct gcgattcggg aagttcgtat tttatattcg gcagtacaag tcttttactg
     2041 ctcattgtaa gatctacacg cttgagtgaa tcgatgatga cgccgtttga atcaacaata
     2101 attatgttgc tgtacatacc cataatttcg catacaacag ttatcatcac agtatcgccg
     2161 agttcgttca cgcactcgaa atcgagcata agaacacggt cgcaaccgtt ctggcgaagt
     2221 cccacaagct ttccgccgcc gattcttttt cgcaaaagca tacagaacat cggaggttgt
     2281 gcaggatttt cgggtgttga cgaacagaag ttcactctcg gtgaatttgc tcgtgcagaa
     2341 agcaacagct ttttgttgcc ggaaaatgtt ctcagcccga acacaagctc ctctctgttc
     2401 ggctgataaa tctgcgacac ccttgcaccg agagcctctt tttctatttc acttttaata
     2461 tgtcttaaaa aaattccgtc aagcgccata gtaactccgt aaattatttg tgatatttac
     2521 cgtttgatga aatctcaaac gcacggtaaa tctgttcgct taaaatcatt cttgccattt
     2581 ggtgaggaaa ggtcattctg ctcattgaaa gacggacatc tgcccgtttt ttaaccgatt
     2641 cgtcaagccc gtagctgccg ccgataataa aatcaacggt gctttttccg cttacagacg
     2701 cattgtcaat cagctttgaa agctcctcac tcgacataga ctttccctca atacacattg
     2761 caacaacata atccgaaggc gaaatttttt gcatgattcg ttttccctca gagaaaataa
     2821 cctcatcaat ctgcgaccta ttcggtatgt tgctcttaat gcgttcttcc gaaagctcaa
     2881 taatattgaa tttacaaaat gcggtcaagc gttttgcata ctctgcaatt gcctcggtaa
     2941 aatatttttc tttgattttg ccgatacaaa ttatgttaat cttaatcata ttcctcttgt
     3001 ttgtttaagg ttaaaagatg atggcttttg ttgtgcttac actcggggca acatcaagcg
     3061 aataatcact tttgtacttc attccgtttg atgtgagcag gtctacggat gttgacattg
     3121 caagcggaac ggtattattt tcttcgctga gatggccgag cataagtctt aaagttccct
     3181 tttcaacaag gttaacaagt tcttttgcac acgcctcatt tgaaagatgt cctctgtttg
     3241 aaaggattct ctgctttagc ggataaggat aaaatccgtt tttgagcata ttgatatcgt
     3301 gatttgactc aagcacaaca aagtcgctct gctctgcggc agttctgaca tcgggcaaca
     3361 taacacccat atcggttgct ataagtgcgg attttccgtc cggagcagta acacggtaac
     3421 aacagctttc cgccgcatca tggggtgtat caattctctg aacacgcata ttgccgatta
     3481 caacctcgtc agttataaca tctgcatctg tgtttggatc aagcttatta cctgccctca
     3541 aagcattgag cgtaccaaga cttgaataca ccttaaagcc gtaacgcttt gcaagcacac
     3601 gcaacgcact gcaatggtct gtgtgttcgt gagttataaa aatcgccccg atactgccca
     3661 tatcaagtcc gtttgcaagc attgcatttt caatctgctt gcatgaacga cctgcgtcaa
     3721 tcagtacgcc ttcgcttgcc gaacctatgt agtagctgtt acccttactt ccgctgaaca
     3781 gcggtactgc tcttgccaaa acaatcaatc cttatcttta gtgtaacgaa tatgataaca
     3841 caaattttaa aatttgtaaa ttatctcaca aaaaagccgt tctcacaaag aaaacggctt
     3901 tgatttctaa ttaaatttta gtcaggcacc gagctcctgc tcgttgtctc ctgtaaaata
     3961 cacctttttg atatctgcac cgagtgctct gaacttttca acaacatctt catatccacg
     4021 ctcaatgaac tgaatattag aaatctctgt tgtaccgtta atttcaagag cggcaataat
     4081 catagccgca cctgcacgaa ggtcggttgc cttaacggga gccgctgtga gcggaacacc
     4141 gccctcaatg attgcaagtc tgccctcaac agaaatctgc gcacccattc tgataagctc
     4201 gctgacatac tgatagcgat tatcccaaac attctcgttg ataatgcttg ttccgggaac
     4261 gctcataagc aatgcggcaa actgcggctg acagtctgtc ggaaagcccg gatgcggcat
     4321 tgtcttgatg ttacagcgct tgagcggagc agatgacgca tcaaccttga gagcctcatc
     4381 atattccgta atcttaacac ccatctcacg cagctttgcg ctgattgatt caagatgctt
     4441 cggtgtaata ttttttaccg taatacaacc tcttgttgcg gcggcggcac acatatatgt
     4501 tcctgcctca atctggtcgg gaataatcga ataagtaatg ccgtgaagat actcaacgcc
     4561 acggattttg ataacatccg tacctgcgcc cctgacatcc gcacccattg aattaagaaa
     4621 gttcgcaagg tcaacaatat gcggttctct tgcggcattt tcaataatgg tctgtccctt
     4681 tgcctttgat gcggcaagca taatgttcat tgttgcacca acggacacaa catcaaggta
     4741 cacatgtgta ccgacaaggc tgtcgcattc tgcctctata atcgcaccgt caacaagctg
     4801 agttgtagca ccgagagcct caaagccttt aagatgctgg tcaatcggac gcacgccaaa
     4861 gttacagccg cccggaagag ccaccttagc cttgccgtac ttgcccaaaa gtgcgccgag
     4921 gagataatat gacgctctca tacctcttac aaggtcggtc acagcattgc atgtacgaat
     4981 ttttgtagga tcaatatata aggacgaacg gttgattcgt cttacattag cacccatctg
     5041 ctgaagaatt ctgctgataa gtgatacatc gctgatgtta ggaatatttt caatctggca
     5101 tggctcatca caaagaataa ctgccggaat aattgcaacg gctgcatttt tcgcaccgct
     5161 gattgtcact tcacccgata atggctttcc gccggtaact acgaacttct ccaattgtta
     5221 caccccaatt aatgtgtaga agatactttt aactaaataa gctaaatatc tgaaaatgta
     5281 tatctatata gtgtataagt aaaaatcaaa aattatacga atctaaaaat tcataatgag
     5341 aactaatttg ttacatttta ttaaaaacga acccactcgg ttacgcagat gtaatttaac
     5401 aattctctta cagaaaatga tactacaaaa ttgtagtaaa gtcaacggaa taataaaact
     5461 gtaatctatt tttggtcaag ttgtactcaa attattaatt tgttgctttt tttgttttta
     5521 atataaccaa ccatgctttt taaaaccgtt ttttcctaaa aagaagtaat taatcaaagc
     5581 aattttttgt aaaataatta caaattgaaa cagttattat attttcttaa ttgaaaattt
     5641 gcaggcaaat ctatcgtata tatttattct ttgcaaatca aacgaataaa acaaaaatat
     5701 ctaaaggtaa attttttaaa aatcacagac aaaatgatta ttatgccgaa aaaaagactt
     5761 tactgccact tgcattgaat ttaaaacttt tatcaattat gattgaaaca gaatcagtcg
     5821 gcaagtgtcc ttttacatta taataatgac aaaattaagg cattgcgaca aatttttaat
     5881 taacggggga ttcagaatga gcgaaacagc aaaagaaccg aaaaaaataa gtaaaagaag
     5941 cagtgaagaa aaaattgaaa ttattgttgc gatttttctc ggaataaccg cactcgccac
     6001 agcatgggca tcgtggatag gttcacttca cggcggaaat caggcgacta actacacaaa
     6061 aagcaacaac ctctcatcag agggcaactc gatgtggaat gaggcttctc aaaatcttat
     6121 gcaggatatg atcacatgga atgacatcaa tgaggcaaac cttaattacc aatatgcgga
     6181 atccaaaaac gataaagcgg aaatggaaaa atatcagtac caaattgatc agcttatgag
     6241 tgataactgt acagaagaat ttcttgaggc aattaattgg gcaatggatc aaaaggaaaa
     6301 tgtaactccg tttatgaagg acggttacac cgaaagctat tttgcagagg caaaagctac
     6361 aattgaagag tcggacaaac ttcttgaaca aggtaagaaa gataacgcaa acggtgacgc
     6421 attcggtctt gtaagcgtaa tttactcggt tgtactcttt atgctcggta tcgtaggcac
     6481 attcaagaat cttccgaaca gaagaattgt gctcggtgtt gcagttgcag gttttattct
     6541 tgccactata tatatgttta caattccgat gccgacagga ttcaatattc tcagttattt
     6601 cggaatggca taaaacaaaa tattctgtac tcacagcggt gaaagcaaat gcttttgccg
     6661 ctgttttttt tgtaaaaaat caaaaaaata ttacactttt ccctctatgt ctattgactt
     6721 tttaaaaatg gaatgctata ttataattaa catatgagca tatcttcata tgttcaagta
     6781 taactattaa cctgagataa aattaaaggg gacgcctatg gaaaacaaag aaaaaacaac
     6841 cactcccgaa atgcccgaca tcgatgtgct gtttgagctc gcagaccttt ttaaggtttt
     6901 cggtgattca acccgacttc gcattatgta caccatttcg gaaaatgaaa tgtcggtgct
     6961 caacattgct gaagctctca acatggagca aagcacaatt tctcaccaac tgcgtgtgtt
     7021 aaggcagaac aagctggtgc gtgttcgccg tgaaggaaag cagatttatt acagccttga
     7081 cgatgaccat gtgaaacgaa tcatagaaat gggacttgac catgttcttg aataaggagg
     7141 gagacatatg aggtacaaat atcagcttga caatctcaac tgcgctcatt gtgcaggcaa
     7201 gattgaggct aaaattgcag aaacagacgg ctttgaggat gtaagcttta attttgcgac
     7261 aaaacttctc aacttcaaaa gcgaaaagca gaatcctgtt tccgaaattc aggcaatttg
     7321 cgacagcatt gaggacggtg taaccgttgt tgacaaaact ccgaaaacca atctcaaaaa
     7381 atacacctac actttagaca atctcaactg cgctcattgt gcaggcaaaa tcgaggctaa
     7441 aattgcagaa acagacggct ttgaagatgt aatcttcaac tttgcgacaa agcttctcaa
     7501 cttcaaaagc gaaaagcaga accctgtttc cgagattcag gcgatctgcg acagcattga
     7561 ggacggtgta accgttgttg ataaaactcc gaaaaccaat ctcaaaaaat acacctacac
     7621 tttagacaat ctcaactgcg ctcattgtgc aggcaaaatt gaggctaaaa ttgcagaaac
     7681 agacggcttt gaggatgtaa gcttcaattt tgcgacaaag cttctcaact tcaaaagcga
     7741 aaaacagaat cctgtttccg agattcaggc aatctgcgac agcattgagg acggtgtaac
     7801 cgttgttgac aaaactccga aaaatgatgt cacaacaaag gcagaacccg aaatcacgaa
     7861 aaagaaaatc aaccgtgaca caatcttcct tgcaatttca attgtacttg ctgtagtgtc
     7921 cgaaattctc caccttacac ttgacggtgt tacggctgtt cattatgttg tactcgcagc
     7981 gtgttttgtt gcaacaattc tttcgggtta caaggtattc atcaagggtg caaaaaacat
     8041 tctaaagctg agaattgacg aaacaacgct tatgtctgtt gcggtaattg cggcattctg
     8101 tcttggggat tttgttgagg cggcaatggt aacaatcctc ttttctatcg gtgaaatttt
     8161 tgaggatcga gcagttgacg catcccgccg tgacattgaa aagcttgcaa acattcgtcc
     8221 cgatacagca acaattattg ttgacggtgc ggaacaggtt gttcctgccg aaagcgttga
     8281 aatcggaagt atcattgaag tcaagccata cgaaagagtt ccgcttgacg gcattattat
     8341 caaaggtaaa acaactctcg acacatcggc tctcacaggc gaaagccttc ctgttgatgc
     8401 aggcgagggc agtgaggtac tcagcggtgc aattaacggc agtaacctta ttactgtcaa
     8461 aaccacaaag catttcggcg acagtaccgc aacaagaatt cttcagcttg ttgaagatgc
     8521 cgccgctcaa aagggcaaca gcgaaaaact tatttcaaga tttgcctctg tttacacacc
     8581 ggttgttgta ctcattgcag ttgcaatcgc agtaattcct ccgctttgcg gactcggcag
     8641 tttcagcgaa tggctctacc gtgcgcttgt ttgtcttgta gcgtcatgtc cgtgtgctat
     8701 tgttatttcc gtacctctct cctactattc cggtatcggt gcggcatcgg aagtcggtgt
     8761 actcatcaag ggcggaaaat atattgaggc tcttgcaaaa gcagatacat tcgtattcga
     8821 taaaacaggc acactcacaa gcggcaagct cagcgtaaac aaggttaata ctgtcggttc
     8881 atacagtgct gacgaagttc ttgctattgc cgctgcaagc gaaaaatatt ccgctcatcc
     8941 gattgcctcc gcaatcagag agaaggcaaa cggtcttgaa cttcccgagc tttccgacta
     9001 cagcgaaagt gccggtcacg gaacaagcgc agtttataac ggcaaaacta ttcagtgcgg
     9061 cggttcaaag attctttcgg acgaacagaa gaaaattgca aacaaagacg attctgtttt
     9121 cgtaatttat gacggtcagc ttatcggttc gctcaatgtc agcgacacgg taagacctga
     9181 ggcaaaagag gttatctcac agcttaaagc gctcggtgtc aagaacacgg taatgctcac
     9241 aggcgacaga caacagcctg ccgaaaatgt taaaaatgaa ctcggacttt ccgaatgtca
     9301 cgcagagctt ctccctgctc aaaagcttga actttttaag ggcttgaaat caaaatccaa
     9361 gggtgcttgc tttgtgggcg acggcatcaa tgatgcccct gttctttcgg caagcgactg
     9421 cggtatcgca atgggattcg gcagtgaagc cgctattgaa gcgtcagacg cagttcttgc
     9481 atcaggcaca ctcaaacagc ttccaaaggc aattaaaatt gcaaggagtg ttatcaacac
     9541 tgtcaagggc aacatcatct ttgccctctc aatcaaggct cttgtaatca tcctcgccgc
     9601 attcggtctt gcacaaatct ggatgtctgt tatcgccgac acaggcgtca gcgtagtctg
     9661 cgtcctcata gccgcaagac tcctcaaaaa gaaatattga tttcctcaac aatcattact
     9721 gttcccgaac aggtaaaact gttcgggaat tttcttgtta ttactcttat acagatactt
     9781 ttttggtcag cattttgctt ttgttgttaa tcatttatta tatctttttc aggcgatgac
     9841 agaataattt aaaatcctgc aaaaaattta atttatgggc aatactgctc tttacttttt
     9901 aaggtattta ttgtataatt agcggtaaag taaaaaggta tatttaatgt tacaaaacac
     9961 cttttgctca caataaaaag gataggaggg acaaaacata atgatcagcg gtgctgaaat
    10021 tatggtaaaa tgtttggaag ccgagggcgt tgacatagtc tttggttatc ccggtgcggc
    10081 tatctgccca ttttacgata aagtttacga ttcgagcatt acccacattc ttgttcgtca
    10141 ggaacagaac gctgctcatg cggcaagcgg ctatgcaaga tgcagtaatc gtcccggtgt
    10201 ttgcgtggca acttccggtc ccggtgcaac caacctcatc acaggcattg caaccgccta
    10261 tacggactct attccgattg ttgccattac aggtcaggtt cgttccgacc ttctcggcag
    10321 agatgtcttt caggaagctg acatcacggg agcttgtgaa ccgtttgtaa agcacagtta
    10381 tctcgtcagc aaaacagaag accttccgag agttttcaaa gaggctttcc atattgcctc
    10441 aaccggcaga cccggtcctg tacttatcga cattcccgtt gatattcagg aaaatgaaat
    10501 tgaaagtttt gaatatcccg aaagcgtaaa cattatcggt tacaagccga acactaaggg
    10561 acacgcaatt caggttaaaa aggctgttga ggccatcaac gcaagcaagc gtcctgttat
    10621 cgtatcaggc ggcggcgtgc tgagttcggg catcaagctt aaacttcaaa aatttgcaga
    10681 aactacgggt atccccgtta tttcaactat gatgggcatc ggtgttatgc ccagcgagca
    10741 tgagctttat ctcggaatgc tcggcactca cggcaaggct gttgccaacc gtgctcttca
    10801 cgaagccgac cttgtaatcg tatgcggtgc aagactcggt gacagagctg ttgcggctcc
    10861 cgaccagatg agtgaaaaca caaaggtaat tcacattgac attgaccctg ctgaaatcgg
    10921 taagaatgtt aaaacagaaa ttccgattgt aggcgatatg aaaaatgtca tcaatatgct
    10981 gcttgacagc atcggcgatt acaaggttac aacaatgtgg agcgaaaccg taaagaactg
    11041 gaaaaaagac ctttaccgtg agcctcccgt atttgacggc tttgttgagc cgagaacact
    11101 tgtcggtcat ctcagtgcaa tgttccgctc gaaggcaatt cttgttgccg atgtaggaca
    11161 aaatcaaatc tggtgtgcaa acaacttccg tattcgtgag ggcagattcc tcacaacagg
    11221 cggtatgggt acaatgggtt actcaattcc cgccgcaatc ggtgcaaagt ttgcaagacc
    11281 cgaccgtgat gttattgtaa tctgcggtga cggcagtttt cagatggggc ttaatgagct
    11341 tgcaactatt gcaggcaatc agctcggaat taaaatcatc attatgaaaa acgcacgact
    11401 cggaatggtt cgtgaacttc aggacaaaca ctacggcggc agacactccg caacaattct
    11461 caacggtgat cccgacttct tgaagattgc cgatgcttac ggcattgacc atgcagaggc
    11521 tcattcaaac gaggaagccg aaaacatcat caagggtatt gttgattcgg aaaaaccgtt
    11581 cattcttgtt tgcgatgttc accccgacac tccgtcaatt taatgaggtg ataaaatgca
    11641 gtatacatta tcaatacttg ttgaaaatca ggcgggcgtt ctttcaaaga tttcgggact
    11701 tttctctcgc cgaggtttta acatcgactc acttgcagta ggtgttactc aggacccgtc
    11761 ggtttcccga atcacaatcg ttgcaaacgg tgacgagtac attgttgaac agcttgaaaa
    11821 acagctcaac aagctcattc ccgttattaa ggtaaaaagg cttaacgagg gcgaatttat
    11881 cagccgtgag cttgtattaa tcaaggttca ctgcgccgcc tcaaaaagag ccgaaattgt
    11941 caaaacggtt gaaattatgc aggcaaaaat cgttgatgta tccccttcgt cagttaccgt
    12001 tgagtactgc gaatgtgcaa gccgcatcaa cacgcttgtt gacttactca agccttatgg
    12061 tatccgtgag attgtaagaa caggtactgt tgccattgac agaggcacag cttcggtttc
    12121 cgtttaatct tacagttagc atatattcta atttatatgc cgcgtttgcg gtaaggagga
    12181 ctttaatatg aaagactaca caaagaacat gacagcacca atctactatc agtcagattg
    12241 taaccttgac cttctcaagg gtaagaaaat tgctattatc ggttacggca gccagggtca
    12301 tgcacatgct ctcaacctca aggattcagg ttgcgatgta atcatcggtc tttacgaagg
    12361 cagcaagagc tgggcaaagg ctgaagctca gggctttaag gtatatacat cggcagaggc
    12421 tgcaaagcag gctgacatca tcatgattct tatcaacgat gaaaagcagg cagctcttta
    12481 caagaacgac atcgagccaa acctcgaagc aggcaacatg cttatgtttg ctcacggctt
    12541 taacattcac ttcggctgca tcaagcctcc aaaggatgtt gatgttacaa tggtagctcc
    12601 taagggaccg ggtcacacag ttcgttcaga gtatcaggtt ggtaagggtg taccttgcct
    12661 cgttgctgtt gagcaggatg ctacaggtca ggctaaggat ctcgcacttg catatgcact
    12721 cggtatcggc ggtgcaagag ccggcgttct tgaaacaaca ttcagaacag aaacagaaac
    12781 agacctcttc ggtgagcagg ctgttctttg cggcggtgtt tgcgcactta tgcaggcagg
    12841 ttttgaaaca ctttgcgatg caggttacga cccaagaaac gcttactttg agtgtatcca
    12901 tgagatgaag ctcatcgttg accttatcta tcagtcaggt tttgcaggca tgagatattc
    12961 aatctctaac acagctgagt acggtgacta catcacaggt ccaaagatca tcacagagga
    13021 tactaagaag gctatgagaa aggttctttc tgacattcag gacggtacat ttgctaagga
    13081 cttcctcctt gacatgagcg atgccggttc acaggttcac ttcaaggcta tgagaaagat
    13141 cgctgccgaa gctcctgccg aagtattcgg taaggaagtt agaaagctct acagctggtc
    13201 tgacgaagat aagctcatca acaactaatg ttttttagtt cgtgaagtta gtttgatata
    13261 ttcaaacttc tgtcacccga gcattacata gtacgaattt agggtagctt gattttcaag
    13321 ctaccctttt tgcgagtacc tcgctcttag ttcgtgtagg tagtttgtga taatttacaa
    13381 ctacttattc ccgagcttaa catagttata attttcggct ctatgtcaat agttggggta
    13441 gcattaaaac agaataattg aaattgacaa g
//
