LOCUS       c00036_gnlPro..        16550 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DAJMCPLM_47.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 13:54:32
            Original ID  :: gnl|Prokka|DAJMCPLM_47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16550
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16550
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2992:6550](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2993..6550
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16550
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16550
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(420..1574)
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGAFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1754..2959
                     /locus_tag="ctg36_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             2993..6550
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="PFOR_II (E-value: 2.2e-18, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.1e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 3.4e-31, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.2e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.1e-11, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00011, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 5.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6675..6863
                     /locus_tag="ctg36_4"
                     /transl_table=11
                     /translation="MIGFVIWIVGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(6874..7734)
                     /locus_tag="ctg36_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNAETIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPKKD"
     CDS             complement(7762..8592)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg36_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.2e-28, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8589..9815)
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKEEREKKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10289..11575
                     /locus_tag="ctg36_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLTLPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFHKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11538..11870)
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(11898..14660)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63.7; E-value: 6.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 4.8e-20, bitscore:
                     63.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWMKTMRYLKWMLVLFCLTGMTACRQDTPRFRIGVAQCSDDSWR
                     HKMNDEILREAMFYNGVSVEIRSAGDDNTKQAEDVHYFMDEGVDLLIISANEAAPMTPI
                     VEEAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLS
                     GSTPAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHND
                     RIAPGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLA
                     MDILEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQ
                     QVVLYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQL
                     SHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNI
                     LLRLVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTD
                     YHTLADMEKLERIYFNLLSNAFKFTPENGRIAVRLSSLCKEDKRWIRFTVANTGSMISA
                     EHIRNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGTISVESDEKQGTVFTVELPVQSC
                     EAVAAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKSSVLIIDDNEDIRSYVHTLLHT
                     DYTVIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTA
                     CSLDEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCD
                     MDKDFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARL
                     KKAASLLASSDMTVAEIGYEVGFSSPSYFTKCYKEQFGESPTDFLKRKG"
     CDS             complement(14984..16210)
                     /locus_tag="ctg36_11"
                     /transl_table=11
                     /translation="MFFSLIVPLFLSLFYKPIAYLCGRSLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 attttagttg atacttatag tagtcaacca aatccagggt aagacaacta ctgttgattt
       61 gattgactta accgcatgtt ccaatcacat tgaacgcatc agctacttca atagtactgc
      121 tctctctgaa aacattaaat catatatcag tcaataatac ataaattatc agtccttaat
      181 acttgatttc tcaattatta atatctgaga aatcaaacgt taacagttga gatatcagat
      241 attaacatcc tgtaaatcaa agaataacac agtaaaaacg gtatttatca ggacgatgca
      301 gagtgagagc aagtccttgc tctcactctg ctaccactgg atctctaaca gctaaaacat
      361 cgatgaataa agggatacag acgaactgtt agagcatgag agcaaaagca ctatcttttt
      421 cactggggga gagtaagcaa aagaaacgca cgataccggc tttgaggcgt caccggtact
      481 aacggcaaat atccggcaca cacccgatta ttctctacgg acaaagggaa cgaagccgac
      541 atctgccgat gttcctccaa agcctgaccg gctaaaggat aataatcaat ccgaaaagct
      601 ccttccgcat ccgcagccaa ataacgatcc gtcaagagcc atgccaccac ccccatattc
      661 attcgcagat taatttcgac acaaggatga atccggtaaa caggcgcttc atccggaaaa
      721 tgacaaatca tcatatccac tcccaagtat ccatgataaa agccaccgaa caaagctgac
      781 aattcttctt ccaaacgagt ccgcagcctg ataaattctt cttgtggcac ataagccgat
      841 agtttctgca gaatcttctc gtcagacagc aagtcattcc ctgcatacat cccactccca
      901 cccgtgtgga agaccgaata tccggcaaaa acaacccttc ctctcccgtc agcataaaac
      961 tccatagcga aatcttccac cttattatat ataggttcgc ctaccacccc accctgagaa
     1021 gcagcgacac gggcacacca accggaaata aaagtagtaa atatgccttt acaccaattc
     1081 aatcctttcc cgcttccgga aagcggagct tttaacaagc acgcttcccg cccttcgacg
     1141 aacgcactgc actccgccaa agtactcaaa taaaaagatt ctccacagaa gtattcattc
     1201 aaccgcaacc caggcaacaa ctttaccgcc tgcagacgat gcgaatgctc tctcagaata
     1261 ttcatataat ccgcagaagg cagctccgtc tgatctgccc ccaatgtcat caaacgcttc
     1321 cgcaaagcag ggtcccaccc ccacggagag aacttccggt ctttaccgtc agccacttcc
     1381 ggttccgtca acaaggccac atccatgccc aaaagttcac tctttgtttt caggaagtcc
     1441 gcattataag cagacggtgc aagcaccgca cttcccgctt cggcatacca cataggaagc
     1501 aacgccaggt cactcgccat ctgtcgggcg gaagccggcg ccatatagtt cgtctcaccg
     1561 cttgccaacg ccatatcatg ctccggattg aatatataaa caggtctttt cgtcatgtca
     1621 aagatggatt caacacatta ttctgcaaat atatacagga aataatcagg aacttacaca
     1681 ataaagagaa acttataaat taaagcacat ttttgctatc tctactttgc aaatcctaaa
     1741 aaaagcacta tatttgccag ccgaaaaaca aagaaacgaa atggaatcat tctatcgcac
     1801 acacgcctac ctcgttgagc acaccaatgc ccccgttcgc cgcgatctta tggacgagat
     1861 cgactggagt gaccgtctga ttggtatcaa agggacacgt ggcgtaggaa aaaccacttt
     1921 cctcctgcag tacgccaaag agaaattcgg caccgaccgt tcctgtctgt tcatcaatat
     1981 gaacaacttt tatttctccg gtcacagcct tgttgacttc gccaacgagt ttcagaaacg
     2041 tggcggaaaa gtactgctga tcgaccaggt gttcaaacat cccgaatgga gcaaagagct
     2101 acgaatgtgc tatgaccgtt tccccagcct gaagattgtc ttcaccggtt cttccgtcat
     2161 gcgactcaaa gaggaaaacc tcgaattgcg tgacattgcg aaaagttata acctgcgcgg
     2221 attctctttc cgtgaatttc tgaacctgca gacaggaatg aaattccggg catacagcct
     2281 cgaagaaatc ctcagtacac atgaacagat agccaaagga gtactttcca aagtacgacc
     2341 gctggattat tttcaggatt acctgcatca tggtttctac cctttcttcc ttgaaaaacg
     2401 taatttctcg gagaatctgc tgaaaacaat gaacatgatg gtagaagtgg atatcttgct
     2461 gatcaaacaa attgagctga aatatctttc aaagataaaa aaattactat atttgttggc
     2521 tgtggacgga ccgaaagctc cgaacgtgag ccaactggca agtgacgtac agacatcccg
     2581 cgctacggta atgaactata tcaagtatct ggcagacgcg cgtctgatta atctggttta
     2641 cccgaaagga gaagaattcc caaagaaacc gtcaaagatt atgatgcaca actctaacct
     2701 gatgtactcc atttatccgg tgaaagtgga agaacaggat gtactcgaca cgttcttcgt
     2761 taacacttta tggaaagacc ataaggtaca taaaggagat aaaaacgtct ctttcatggt
     2821 agacgaagtg atgccgttca aaatttgtgc ggaaggtaca aaaataaaga ataacccgga
     2881 cgtgacgtat gcgttgcaaa aggctgagat aggccgcggc aaccaaatac ctctttggat
     2941 gttcggattc ttatactaaa aagatttatt tacttaaata tttaatttag ttatgactaa
     3001 acagaagaaa ttcatcacat gtgatggtaa ccaagctgca gcacatatct cgtatatgtt
     3061 ctctgaagta gcagctatct accccatcac tccttcttcg actatggctg agtacgtaga
     3121 cgaatgggct gccgcaggac gtaagaacat cttcggcgaa acagtattgg tacaggaaat
     3181 gcaatctgaa ggtggtgctg ccggtgcagt tcacggttct cttcaggctg gtgcattgac
     3241 tactacttac actgcttctc agggtcttct tttgatgatc cctaacatgt acaagattgc
     3301 cggtgaattc ttgccttgtg tattccacgt ttctgctcgt acactggctt ctcacgcatt
     3361 gtgtatcttc ggtgaccatc aggacgtaat gtcagctcgt caaaccggct tcgctatgtt
     3421 ggcagaaggt tctgtacagg aagttatgga tttggcaggt gttgctcatc tggctactat
     3481 caaatcacgc gttccgttca tgaacttctt cgatggtttc cgtacttctc acgaaatcca
     3541 gaagatcgaa atgttggaaa acgacgacct cgctccgctg atcgaccagg aagctttggc
     3601 tgaattccgt gcccgtgcac tgaatccgat gaagccggtt gcccgtggta tggctgaaaa
     3661 ccccgaccac ttcttccaac atcgtgaatc atgcaataac tactatgaag cagttcctgc
     3721 tatcgtagaa gaatacatga acgaaatttc caagatcaca ggccgcaaat acggtttgtt
     3781 cgattactac ggtgcagaag atgcagaacg cgtaattatc gcaatgggtt ctgtaactga
     3841 agctgcccgc gaagctatcg accacttggt agcaaacggc gaaaaagtag gtatggttgc
     3901 cgtacacttg tatcgtccgt tctctgctaa acacttcctg gctgctgtac ccaagactgc
     3961 aaagagcatc gcagtgcttg accgtacaaa agaaccgggt gctaacggcg aacctcttta
     4021 ccttgacgtt aaagactgct tctatggcgc agaaaatgct cctgttatcg ttggcggtcg
     4081 ctacggtctg ggttcaaaag ataccactcc ggcacagatc atctctgtat tcgaaaactt
     4141 ggctatgcca atgccgaaga accacttcac tatcggtatc gtagacgacg ttacgttcac
     4201 ttctcttcct cagaaagaag aaatcgctct gggcggtgaa ggtatgttcg aagctaaatt
     4261 ctacggtctg ggtgctgacg gtacagtagg tgccaacaag aactctgtta agattatcgg
     4321 tgacaacacc gacaaacact gtcaggctta cttctcttac gactccaaga agtcgggtgg
     4381 tttcacttgt tctcacctgc gtttcggtga tactccgatc cgttctactt acttggtaaa
     4441 tactccgaac ttcgttgctt gtcacgttca ggcttacctg cacatgtacg atgtaacacg
     4501 tggtttgcgt aagaacggtt ctttcttgct gaacaccatc tgggaaggcg aagaactggc
     4561 taagaacctg cctaacaagg tgaagaaata ctttgcacag aacaacatct ctgtatacta
     4621 tatcaacgca actcagattg caatggaaat tggtctgggc aaccgtacca atacaatcct
     4681 tcagtctgca ttcttccgta tcacaggcgt tattcctgta gatcaagctg ttgaacagat
     4741 gaagaaattc atcgttaagt cttacggcaa gaagggtgaa gacgttgtta acaagaacta
     4801 cgctgctgta gaccgcggtg gtgaatacaa gactctgact gtcgatcctg cttgggctaa
     4861 cctgccggat gatgcaaaag cagaaaacaa tgatcctgct ttcatcaacg aagtagttcg
     4921 tccgatcaat gcacaggacg gtgacttgct gccggtatct gcattcaagg gtatcgaaga
     4981 cggtacttgg tatcaaggta cttccaaata cgaaaaacgt ggtgtagctg cattcgttcc
     5041 cgaatggaat gctgaaaact gtattcagtg taacaagtgt gcttacgttt gtcctcacgc
     5101 ttctatccgt ccgttcgtac tcgatgctga agagcagaag ggtgctaagt tcgagcaact
     5161 gaaagctgta ggtaaagcat tcgatggtat gacattccgt attcaggtag acgttctcga
     5221 ctgtctgggt tgcggtaact gtgccgacat ctgtccgggt aatccgaaga agggtggcaa
     5281 ggcattgacc atgaaacacc ttgaaagcca gttggccgaa gctgataact ggacttactg
     5341 cgctgaaaac gtgaagagca aacaacacct ggtagacatc aaggctaacg tgaagaactc
     5401 tcagttcgca actccgttgt ttgagttctc aggcgcttgc tccggttgtg gtgaaactcc
     5461 gtacgtgaaa ctgatttctc agttgttcgg tgaccgtgaa atggttgcta acgctacagg
     5521 atgttcttct atctactcag gttcagttcc ttctactccg tacactatga acgaaaaggg
     5581 tcacggtcct gcatgggcta actccttgtt cgaagacttc tgtgaatttg gtctgggtat
     5641 ggaactggct aacgaaaaaa tgcgtgcccg tctggtgaaa gtaatgaacg aagctatcgc
     5701 ttctgattgc tgcccagctg aatacaaaga agtattcgct gaatggatca acaatatgct
     5761 ggatgcagaa aagactaagg aactggctga aaagatcatt ccgatggtag aagctgctaa
     5821 agataaatgc aaccactgca agcaaatcgc tgatctgcaa caatatcttg ttaaacgtag
     5881 ccaatggatc atcggtggtg acggtgcttc ttacgatatc ggttacggtg gtcttgacca
     5941 tgtaatcgct tccggtaagg acgttaacat ccttgtattg gatactgagg tttactctaa
     6001 cacaggtggt cagtcttcta aagctactcc ggtaggcgct atcgctaagt ttgctgctgc
     6061 aggtaagcgt gtacgtaaga aagacctcgg tctgatggct actacttacg gttatgtata
     6121 tgttgctcag attgctatgg gtgctgacca ggctcagact ctgaaagcca tccgcgaagc
     6181 tgaagcatat ccgggaccat cactgatcat cgcttacgct ccatgtatca accacggtct
     6241 gaaagccggt atgggtaaga gccaggaaga agaagaaaag gctgttaagt gcggttactg
     6301 gcacttgtgg cgttacaacc ctgctttgga agaagaaggc aagaatccgt tccagctgga
     6361 tagcaaagaa cctaactggg aagacttcca aggtttcttg aagggtgaag ttcgttacgc
     6421 ttctgtaatg aaacaatacc ctgctgaagc tgaagaactg tttaaagctg ctgaagaaaa
     6481 cgctaaatgg cgttacaaca gctacaaacg tcttgccaga gaaaactggg gagctgatac
     6541 agctgaataa taagtagaaa tactttgtac ataataaaag gcaggaatcc tggaaacaga
     6601 ttcctgcctt ttttgtttat atattagaag taacgattac ttctcacgaa gatattcatt
     6661 aaaactctaa agatatgatc ggatttgtta tttggattgt cggtttgata ctgactttca
     6721 gagctgccat agagatttgg aatataaatg cggctgtaga gaaaaggctt atagcgattg
     6781 tattaatcgt tcttaccagc tggctgggac tacttttcta ctacttctat ggtaaagaaa
     6841 gaatggcggg atggttgaag tagtgtttgc ttatcaatct ttcttaggaa tccaactgtt
     6901 taccagttcc tgatgttctt ccatccattg acgggcagcc tgtctttccg tcgtctgcgc
     6961 ctcttccaga gcagtcatta aagagctgat ttccgcatca gtcagacgaa tattgcccag
     7021 aagttcggca gcaaaaggat ctttctcgct aaaacctttc cacgctatgg tatgaatggt
     7081 ttccgcattt ccatatatca gcttcgggtc ctgaagaact ttcagtttga aacggtcgaa
     7141 catccagtga ggcgtccatc ccgtcacgac aatccagtct ttcttatcaa tcgctttctt
     7201 tagggaagca gtcatggcag gtccgctcga agtcatcagt ttataatcca atccatagtc
     7261 tttgatggcc tgatcggtag ctttcataat accggctccg gcatcaatac cgacaatctg
     7321 accggagaaa cgttcctttt ccgcgttcag ttcttcgatc gagttgatcg taacgtaatc
     7381 cggaaccacc agcccgatac gggcaccatc ataaatatcc ccgataactt cgagtttatc
     7441 cccgtattgt ttcatataat cttccatagt gacaggcatc cagacatcca taaatacgtc
     7501 tgctttctta cgggagatag aggtaaatat aggtgcaagg tcggcattca gcaactttac
     7561 atcgtatccc tgatcttcaa aaatcgcttt ggcaaggttt gtcatggcaa tcccttccga
     7621 ccagttggca taagcgatac ttatcttctt actctttccg ttgtctccgc aggaaacgaa
     7681 ggttaagagt atgccggcaa taaacattgc cgcaatcatt tttatcttat tcattgatta
     7741 ttcctttctt tggtgtgatt cttatttctt tttacttttt ctgttatctg ccatgccctg
     7801 agtgatgcgg tccagcacga tcgccaatat cacgactgcg ataccgcctt caaatccgag
     7861 tccgattttc atttgggtga tacctttcag cacgatttct cccaatcctc cggcagaaat
     7921 catggcggca atcactacca tcgaaagtga catcatgatc gtctggttga ttcccgtcag
     7981 aatagtaggc aacgccaaag gcaattgtac cttataaaga agctgccagg gagtagctcc
     8041 aaaagagcgg gaggcttcta ctacgttttt aggaacctga cgaatgccca ggccggtcag
     8101 acgaaccaca ggaggcattg caaagatgat ggtggcaaaa gctcccggca cagttcccaa
     8161 tccgaagaat agaacggcag gaatcagata gacaaaggca ggcattgtct gcataaagtc
     8221 gaggacaggg cgcattatct tgttacaacg atcactgttg gcagtccaga ttcccagcgg
     8281 aacgcctaaa agcaatgcca gacaagtgga agaaagtact aacgccaatg tctgcatcgt
     8341 ttcttcccaa aagcccatgc cgtaaataag caataagccc aagagggtaa atacggctgt
     8401 ccccttaccc gacttaaacc aggcgagcgc agccagcact gcaattgtga tataaaaagg
     8461 tattccaaac agtacgtgct gaaaaccgtc tatgaatcct ccgatcccca tgctgagagc
     8521 atcaaaaaag gaagcaaaat gttctgtgag ccaattaatg gcagtttcta tatattgtcc
     8581 gatatttatc ataattctat tgcgttttga atgatttcat taatttcttc tttatctttt
     8641 cccgttactt cgatgatcaa tgaggaaagt ggcactacgc cttcaaactc ccgattctca
     8701 tttacgaccc agattggcga gttcgttttt gtcatcaacg gaagaatatc ttccagcacc
     8761 gtatcaccca gcactgaatg aacttcatgc cttactacgg actcgatgga gcggatttgc
     8821 tcttttcgta gtttcagcaa gtcattcaac cgcacctctc ctactaacag attattggaa
     8881 tcgactaccg gaagaacggt cagattccgt tcgcgcatct tacggatcag cacctccggg
     8941 ccttctttct tcaaacgtgc cactatgggt ttatctacca taacagagga agctgttata
     9001 atcttgcttc gatctacatt ctccacaaat cgttctacat aagcgttggc aggttcggtc
     9061 aggatttctt ccgatgtacc gatttgtaca atttctccat ccttcatgat agcaatccgg
     9121 tcacccaatt taatcgcttc actcaggtcg tgagtaataa agacaatcgt ttttttcatc
     9181 ttcgactgca aagtcagcag ttcatcctgc atctgcacac ggatcaaagg atcgagtgcc
     9241 gagaaggcct catccatcaa caggacttcg ggattattgg ccaaagcccg cgccagcccg
     9301 acacgctgct gcatcccacc cgacagttca cttaccatct gattctcgta gcctttcagc
     9361 cccaccagtt gcatactttc catcgctttc ttctcccgtt cttccttttt aactccctgt
     9421 agttcgagtc cgaaagctat attatgcaag acagaacggt gaggaagcag accgaagttc
     9481 tgaaagacca tagccagttc tttccggcga atctgcaaca gttctttatc cgacactttg
     9541 gctatgtctg ttccattgat aatcacttct ccggaagtag ggcgtatcaa acggttgatg
     9601 cagcggagta aagtggactt tccactaccg gacaacccca taatgacgaa tatttcgcct
     9661 tcattaatgg aaagattcgc atctttcacc gcaaccgtac atccggtcgc tttcaatatt
     9721 tcacttttag ttttaccttc tttcaacatc ttcaaagcct tctgcttctc attgccaaaa
     9781 accagataga gatctttaat ttctatttta ctcatacaat aaaatggttt aggttattaa
     9841 aataatatac acagcaagac aagaacaaac gataacagga atctttcttt atatcgtata
     9901 aagttctgat ttaaatacgg gacaaataac aatgaatccc gaaataatta ataaaatgat
     9961 tattgacaga ctgagtaatt aaaaaaggaa tagaatttga taagataatc ctttcaacga
    10021 atagcaaaaa aatagcattt ttatgtataa aaacagtctg ttccagtatc ttgctggcac
    10081 aaagatacaa aaaacagatt aaacatgcaa attatattca aaatccgggg catacagagg
    10141 actttatttg taatgatatg gaaagtttcc gggtaatatt cccctatcac tcagcaaaat
    10201 agaacaaacc agcagataaa tataaaataa gtttgaatat ttcacctaaa caccgtatat
    10261 ttggcgtcaa taactaaact agatttatat gttcaacagg gctattacaa ttttcctggg
    10321 gaaggataat tgtcattaca caacaaaaga aaaacaaaca ggtactgcca cactagacga
    10381 caaaagccaa gtacagttcc ttagtaaaaa gaaccccaaa atgccgtttt tctatagtcg
    10441 gcggaatctc tacatgatag gtttcctgct cgcttttata gtgactctgc tcgaatttat
    10501 gcgaggacgg catcaaaact ttatggtctt ctcagacgct actcaattct tctggcaagg
    10561 catcagccca tacacaaccg aatttgtaga agctcacgga cgctacttcc tttattctcc
    10621 tgttttcacg gtattgttcg ctccgtttgc gtatctgcct gcatggctgg gacctttcgc
    10681 gtggaatcta ttcaattatt cattgttctt tgtggcgatc ttcacgctgc cccaacaatt
    10741 cacccagcaa cagaaatgcc gtatgttcct ttttctgtta ctgattttag gacaaagttt
    10801 actttcattt cagtataaca taacggtagc ctatttattc ttattcgcct atacgttatt
    10861 ggaaaaagac cgtggatttc tggctgttct gttaatcatg atttcgggat gtaccaaagt
    10921 atatggaatt ttcgaactgg cattgttgct gtgctatcct cacgtatggc gtaactttgg
    10981 ctatgccgtt gcaatgggca ttgtattgct tacgttaccg ttaatcaaaa tagctcctgc
    11041 agatttgctc ccctattatg aagaatggtg ccatagtctt gctgttcatc aatccgccgg
    11101 agcttatgat tcatttttct atgcccgccc cattgcagca tggacattgc cacacttccg
    11161 tgcacttcag ataggaatgc tcggtctact gactctgctc tttttgggga atttccacaa
    11221 atggtcgtct tttgccttcc gtgcccaagc tttgggcatt ctcatgggct gggtagtatt
    11281 actgagtgac tccgccgaga aacataccta tattatcgca ttggcaggtt tcatgctctg
    11341 gtattggagc aggccaacac gtaccgcaac agacaagatt ctattttggt gctgttttgt
    11401 gctgttatgc atcgttccta tcgacatatt cgtccctgtt cccatcagag atttcattac
    11461 caggacctta tggcttcatg tatgggtttt ctttattgta tggatacgga tgatatggct
    11521 taccttcctt gcatccttca ttcatccacg tgccacaaat gttctttcag attaacgcat
    11581 ccgttagctt tgaaagaaac ttcttctgcc agcaagagtt gtttttgttc cacccaaccg
    11641 ggtaccagcc ttccggtgga atttacaact ctatggcaag gaatggataa ttcatccggc
    11701 acttctttca atgcacgccc caccatccgc gaacattggg gggcacccaa aagcaaagca
    11761 atacctccat aggtagatac ttttcccaca ggtatctggg atacgacttc gtacacttcc
    11821 ttccgaaagg attcggaaaa actctcttta tctactttat aatctttcat atatccctct
    11881 ttacgatctc aatgaaatca tcctttcctt ttcaggaagt ctgtcgggct ctctccgaac
    11941 tgctctttat agcacttggt gaaataagaa ggtgaactga aaccgacttc ataaccaatc
    12001 tccgctacgg tcatgtccga agaagcaagc aaagaagctg ccttcttcaa acgggcgata
    12061 cggagcaatt cattcggaga gtagttagtc aacgatttaa tcttgcggta aagctgcaca
    12121 cggcttagtc ccatatcctt gcccaagtcc tccacattca aaccggagtc tcccattttc
    12181 tcttcaatca atgacttgaa tctttctaca aaatccttgt ccatatcgca aacatcttcc
    12241 ttcgccaatg tctgcccgtc accaaagaac tgtttcagac gacggtgaga atcgatcagg
    12301 ttgcggacac gtgccagcaa cagttgtgaa ctgaacggct ttgaaatata agaatcggca
    12361 ccaccgtcat atccctgaat acgctgttcg tccagtgaac acgccgtcag cagaataacc
    12421 ggaatatgac aggtctgtaa ctcacttttc agccggcggc aacattcaat gccatcaatg
    12481 cccggcatca tcacatcgga aataatcagg tcaggaacat acttcatagc cttacggatt
    12541 ccttcggagc cgtctgccgc ttcaatcacc gtatagtctg tatgcaacag cgtatggaca
    12601 tacgaacgga tatcctcatt atcatcaata atcagtacgg acgatttgga agagtcatat
    12661 cctttttcca gttcttcctc ttccgccaat agaacatctg ttgtacggga atccgcagaa
    12721 acaagggtgg tatccggttc ggcagcaaca gcctcgcaag actgtacagg cagttcaacg
    12781 gtaaagaccg taccctgttt ctcatcgctc tctacagaga tcgtaccacc atgcatttct
    12841 acgaaggctt ttaccaatgc cagtccgatt cccgaaccgg tatggtgcat atcgatctta
    12901 tagaaacggt cgaatacatt gcggatatgt tcggcagaaa tcatagaacc ggtatttgcc
    12961 accgtgaaac gtatccatcg cttgtcctct ttacaaaggg aagacagacg aacggcaatt
    13021 cttccatttt ccggtgtaaa cttaaaggca ttggacagga gattgaaata aatacgttcc
    13081 agcttctcca tgtctgccag tgtatgataa tccgtatccg gcatactatc aaaagaaaaa
    13141 tggatatgct tcttacgggc tgccgcctga aaagactcat tccatccttc gaaagaagaa
    13201 aggacatcca ccgtaaccgg agtatattcc atcttgccat tttcatattt acggaaatcc
    13261 agaatctgat tgaccagacg cagaagaatg ttcacattcc gctgaatcag catgagcatc
    13321 cggtgctgat ctccgctcag tgtcttgtcc gccaacaaat gttctaccgg atcggcaacc
    13381 aatgtcaacg gagtacggaa gtcgtgagaa atattggtga agaataccag cttggcatga
    13441 gtagcttctt ccagttgatg agaaagttgt atcaattggt cacgctgttc ttccagtttg
    13501 tcacgttgct cttccaattg ttgcttctgc ttaaaaagtt ctttattcaa gcgattcttt
    13561 gagcggagtg atttataaac gaccaataat aagccggcta ccaataaaag gataatcaga
    13621 ctgccgtata aaacgacctg ttgtgtagct acctgagaga gatagccacc gatacgtccg
    13681 ttgagcgttt caatcttttt gtcgagttcg gaaatgtgtg tggtctgcaa ctgcatgacg
    13741 tgtgcgttgg tacggtccac aacagcggta ttcatcaccg tttctttggg atagggtttc
    13801 ttctccagaa tatccatagc cagttgcagt accttatcac cattggtcgg atagataaag
    13861 gtagcatcca gcacactgtc cagaaccagc tccagcccgt ttcccttacc cggcaaggca
    13921 tctatgccga caaaaatcat ttccttctcc cgccctgcca tctttgctgc ctgataggca
    13981 cccggagcga tacgatcatt atgggcatac acagcatcaa tcttaggatg cctccgaagc
    14041 atactatcca tttctatctc tgccggacca cgttcccaag cagcatccgc tttatcaatc
    14101 agctttatat ccgggaattt actgatggca gccataaatc cctgatgccg ttccattgca
    14161 ggagtcgaac cgctcaatcc tgtcagttct actatatttc ccttcccttt cagactggag
    14221 gcaatatagt ttcctaccga acgaccgatt tcataattat cggctccgat ataggcagta
    14281 tatttatccg aaagaatctt ccggtctaca agaataacgg ggatgccttt ctgataagct
    14341 tcttctacaa tcggagtcat aggagcagct tcgttagcgg aaataatcag cagatcgact
    14401 ccttcgtcca taaaataatg gacatcttcc gcctgcttag tgttatcatc ccctgccgaa
    14461 cggatttcca ccgaaacacc attataaaac atcgcttccc gaagaatctc atcattcatc
    14521 ttatgtcgcc atgaatcatc gctgcattga gccaccccaa tacgaaaacg gggtgtatcc
    14581 tgccggcaag ccgtcatccc ggttaaacaa aacagcacca gcatccactt cagatatctc
    14641 atcgtcttca tccatctcat catttcgtag ttctttctgt aatccaatta agaacaaaaa
    14701 taagaaataa tactgtaaag ttctctaact tcagctattt attattctaa aaagaaggaa
    14761 agcagtcctc tttcagacca tcggaaagta ttaacaaaag tataaagcgt aaaacaaaca
    14821 cttaatcaat gttataaaac atagcgtttt acttggataa tttgcagatt tcacagaagt
    14881 ccgtatcttt gtactgtgtt tttcatagta ttagatttaa ggttaacaaa ggttggagca
    14941 aggcgttgct ccttttttta tgccctgacc tttcatctac cggttagttt tcatcccatt
    15001 ccttttccag tttaccatca atagtgtagc gtttccatcg tcctacacgg cgaccattct
    15061 tatattcccc acattcacga agctggtcat tctttacata acgagcttcg aacggtccgt
    15121 tctgccttcc gttcacatag gtagaagttt cccaataatc aaagcggttg ctcactatca
    15181 gccgtcgttc cttgccatgc aatctgccgg cctgataggt agcttcatat ctcaattcac
    15241 cattttccaa attatattca cggtataaac cgtctttacg atcgttcttc atataatatt
    15301 ctttctgcct taccccactt ccgttggcaa atgagacatg gagtccatct tcttttccat
    15361 ccagataggt ttcaatcatc agcgtatcgc cgctttcagc aaaagtagtc caacgaccat
    15421 tcttctttcc attcttataa ctacccagta tacgtggcga gccaaacgta aacacggacg
    15481 aatattcacc gtcctgaaaa ccttcttcat tgaaataaac ggtctcatac aaatcatatg
    15541 tacctttcag aaaagtatac tgtttgccta cctgcttccc gtccttgtaa ttatgctctt
    15601 tccgcaaagt accgtcagat tcgtacgaca gttgcttccc gtgctctttc cccatccgga
    15661 agtttctttc actttccact tttccggtag taaagtaact tttgctcgta ccgtccagct
    15721 taccttcctt ataggacttt tcttctttca gcttaccgtc aaacttggag ttaatcttga
    15781 agagaccatc cttccgtcct tctttataac ttccttctgt tattaatata ttgtctacat
    15841 attctttgta tccgccatca tagaaaccat ctttaaaaga tgccagcaca taggcggaat
    15901 gataaccatc tatgatgcga tgttcgccat tcaatgcttt ttccgttttc agttcctgaa
    15961 acaacagtct gccatcgcct acattgacaa cggatacctg atcgatctta tattcctttt
    16021 gcgcaaacaa aggaagagca agatataaaa acaaaaatac gttccagctt tttgatctga
    16081 ggaagtttga aatgtgtttc ataaagtagt tttctctttt tgatttatta tttaaagacc
    16141 tgccgcaaag ataggcaatc ggcttataaa acaaggaaag aaagaggggg acaattagag
    16201 aaaagaacat ctgttattat cattctaata attaacagat taagtagtaa atcaaaacac
    16261 agggaagggg gatatttact gaaataagaa acagaaaaga agatgtgtca aaagtaacta
    16321 aatttccctc cttcaggaag gaggggtggc tgaaagccgg ggtggtaggt atatttcaca
    16381 gttgaatatc aatagcttat gtattcacct accacctccc cctacgagta ctcctccttc
    16441 ccgaaggagg agagtttagt tacttttgac acacctgctt tttgtattta aagagattct
    16501 acaacaatct gtctttcaga acaaccggaa gttcgggcat tgcaccgctc
//
