LOCUS       c00043_gnlPro..        13963 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DAJMCPLM_54.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 13:54:32
            Original ID  :: gnl|Prokka|DAJMCPLM_54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13963
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13963
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[992:3963]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      993..3963
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13963
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13963
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             993..3221
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_1"
                     /sec_met_domain="Gly_radical (E-value: 3.2e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             3235..3963
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73.7;
                     E-value: 6.1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_2"
                     /sec_met_domain="Radical_SAM (E-value: 3.8e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFKLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQGKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(3956..4405)
                     /locus_tag="ctg43_3"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(4392..4559)
                     /locus_tag="ctg43_4"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDKVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(4619..5122)
                     /locus_tag="ctg43_5"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVLTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             5316..5546
                     /locus_tag="ctg43_6"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             5633..7747
                     /locus_tag="ctg43_7"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     DYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCRIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKISNRKNLSGSKQQTPPDGTPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEETSAFIK
                     SQFTDFPADETVSLINSAYAHTDEFNTCKLNGTQKRRLRIEQYISEHYETRYNEVLHIM
                     EYRRRRPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(7817..8122)
                     /locus_tag="ctg43_8"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(8103..8435)
                     /locus_tag="ctg43_9"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             8452..8868
                     /locus_tag="ctg43_10"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPTKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRREIGKTQPSFFDFSPHFQINPPIEADFRKYLLSL
                     MCKRSKESDMGNLMRKLPIGIQTFEDIRRKNILL"
     CDS             complement(9025..9279)
                     /locus_tag="ctg43_11"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYISVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGDFK"
     CDS             complement(9297..9431)
                     /locus_tag="ctg43_12"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSEKLLELIDQKKELSSN"
     CDS             complement(9549..10907)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 152.3; E-value: 5.7e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg43_13"
                     /sec_met_domain="MFS_1 (E-value: 4.7e-47, bitscore: 152.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDSERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     RGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSAICLFLLVP
                     GVHFWVDALAMVLFGLGIGVLICFLGGLMAVDIAPCNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINWFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             complement(10923..11843)
                     /locus_tag="ctg43_14"
                     /transl_table=11
                     /translation="MKKYIMIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRA
                     DWRYAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVD
                     QIIMKGSKPVADVKNDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVS
                     DTCQVPKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQT
                     DRTAYLLEYLQSRKKRSENGQDAYH"
ORIGIN
        1 tcattgtgct tttggaacaa tgaaaggatt gtttcgtggc tctcgctgtg tcccaagaac
       61 tcgtttttca ctttctcggc ggtcacgtaa ttgtcacgcc gctgcatttc gtggtaaatg
      121 gtattcaggg aagaacgtat gtcgtccaaa agggcgttta tcctcccggc atccctgcct
      181 ttggctttgc ccgcagcaat gctccagttg tcgggctgga tgctctgttt cgtactgaac
      241 tggcaaagtt tgccgtctat ggtgatgcgt gccataatca taacctcgcc gtttttcttt
      301 tcagaacctt tcttcaaata aaaaagaacc ttgaatgtcg attnnnnnnn nnncctttct
      361 tcaaataaaa aagaaccttg aatgtcgatt tcataactca ctttttttag ttgcaaaatt
      421 aatttttacc tctcgttttc gagttatgca gactatggac taatcaagtc attatcaggt
      481 catttatgga caaatcgtta ccgtttttgt ccggcgggga ataggtaacg atttagtaac
      541 gaaactttgt cttttaccgt acttttgaag tcttggaagc aggactttcg ggcaataaaa
      601 aaagccacaa atcattgatt tgtagctttt tgtccgtttg ctgaccattt ctgtccagca
      661 cgttcagcgg agagacaggg attcgaaccc cgggtacctc gcggtacaac ggttttcaag
      721 accgccgcaa tcgaccactc tgccacctct ccaaaacttc cttgtcagaa gtgcttttcg
      781 ttaaaagcgg tgcaaaggta cgaagatatt ttaaacttgc aagagttttc actaaaaatt
      841 taatctaatc ttttcctaag gatagcaatt aataggtatt ttatgttgaa aagcataaaa
      901 tagagcatat ttatgctgat tatatgaaaa atgattgtaa ctttgtgcgc tctaaagaat
      961 aggataacta caacctctaa ttttatcatt ttatggaatt aaacaagatc tttaaagacg
     1021 gtctttggag cagcgaaatc aacgtcagag atttcgtaag tcataacatc actccgtatt
     1081 acggagatgc ttcattcctc gaaggaccta cagaacgtac caaagccgta tggaaccgct
     1141 gcctcgaagc actggcagaa gaaagagaaa acaacggtgt ccgctcatta gataatgtta
     1201 ccgtatcaac catcacttcc cacaaggccg gatatatcga caaggaaaac gaactgatcg
     1261 tcggcctgca gacagacgaa cttctgaaac gtgccatcaa gcctttcgga ggtatcaacg
     1321 tagtcagcaa agcctgtcac gaaaacggcg tggaagtgga cgaccgcgta aaagatattt
     1381 tcactcacta ccgcaagacg cacaacgacg gagtattcga cgtatatacg gaagaaatcc
     1441 gttccttccg ttcgctggga ttccttaccg gacttcccga caattatgca cgcggacgca
     1501 tcatcggtga ctaccgccgt atggctcttt acggcatcga ccgtctgatc gaagcaaaga
     1561 aggaagattt gcacaacctc accggtccga tgacagaggc ccgcatccgc ctgcgcgaag
     1621 aagtggcaga acagatcaag gcactgaaag acatgaaagt gatgggcgaa tactacggtc
     1681 tcgacctgag ccgtcccgct tacacggcac aagaagccgt acagtgggta tatatggctt
     1741 accttgccgc cgtcaaagaa caagacggtg ccgctatgtc actgggtaac gtttcttctt
     1801 tcctcgatat ctatctggaa tatgaactga gcaaaggaac catcaccgaa tcgttcgcgc
     1861 aagagctgat cgaccagttt gtcatcaaac tgcgtatggt ccgccacctg cgtatgcaat
     1921 catacaacga catctttgca ggcgacccga cctgggtaac cgaatctctg ggcggacgtc
     1981 tcaacgacgg acgtaccaaa gtgacaaaga cctccttccg ttttctgcag acattgtaca
     2041 acctcggccc ttcaccggaa ccgaacctga ccgtactctg gagcccggaa cttccggaag
     2101 gattcaaaga attctgtgca aaggtttcta tcgacacttc ttctatccag tacgaaaacg
     2161 acgacctgat gcgtgaagta cgtcagtccg atgactacgg aatcgcctgc tgcgtatcat
     2221 accaggaaat aggcaagcag attcagttct tcggtgcccg ttgcaacctg gccaaagccc
     2281 tgttgcttgc catcaacggc ggacgttgcg agaataccgg tacagtcatg gtgaagaaca
     2341 tccccgtact gaccagcgac acgctgaagt tcgaagaagt aatggacaac tacaagaaag
     2401 tgttgaccga aatcgcccgc gtatacaacg aagcgatgaa catcatccac tatatgcacg
     2461 acaagtatta ctacgagaag gcccagatgg ctcttgtaga tacgaacccg cgcataaacc
     2521 ttgcttacgg tgttgccgga ctttccatcg cactcgactc actgtctgcc atcaaatatg
     2581 cgaaagtaac tgcccgccgc aacgatatcg gcctgacaga aggtttcgac atcgaaggag
     2641 aattcccttg cttcggtaac gacaacgaca aggtagacca cctcggcgta gacctggtat
     2701 acttcttcag cgaagaattg aagaaattgc ctgtttacaa gaatgcccgt cctaccctct
     2761 ccttgctgac tatcacttcc aatgtgatgt acggcaaaaa gaccggtgct actcccgacg
     2821 gacgtgccaa aggtgttgcc ttcgctccgg gtgccaaccc gatgcacgga cgcgataaga
     2881 atggtgcgat cgcttctctg agctctgtag cgaaacttcg ttaccgtgac tcacaggacg
     2941 gtatcagcaa caccttctct atcgttccga aatcactggg tgctacggac gaagaccgta
     3001 tcgagaacct cgtaacgatg atggacggtt acttcaccaa aggtgcccac cacctgaacg
     3061 taaacgtact gaaccgtgat atgctatacg atgccatgga gcatccggag aactatccgc
     3121 agctgaccat ccgcgtttcc ggttatgccg taaacttcgt gaagctgagc cgcgaacacc
     3181 aactggaagt tatcagccgt agcttccacg aacgtatgta atctattact ctatatgatg
     3241 ataaacgtac attcatacga aagtatggga acattcgacg ggccgggctt acggctcgtc
     3301 gtttttcttc aaggatgcaa cttccgctgc ctctattgcg ccaatccgga tacgatagca
     3361 ggaaagggag gcacgcctac cccaccggaa gaaatcgtcc gcatggcaat gagccagcgc
     3421 cccttcttcg ggaaacgagg aggaatcact ttctctggag gcgaaccgac gtttcaggcg
     3481 aaagcactcg tcccgctggt ccgcgaactg aaagaaaaag gcatccatgt ctgtctggac
     3541 agcaacggag gactttggaa cgaagacgta gaagaattat tcaagctgac cgatcttgtg
     3601 ttattggata taaaggaatt caatcccaac cgccatcaga cgctcaccgg aagaagcaac
     3661 gagcaaacca tccgcacggc cgcctggctg gaagaacagg gaaaaccttt ctggctgcgt
     3721 tatgtgctag tgcccggata cagcgatttt gaagaagaca tacgcgcact gggagaagca
     3781 ctcggaaaat acaagatgat ccaacgggtg gaaatactgc cttaccatac actgggcgta
     3841 cataagtacg aagcgatggg acaggaatac aagatgaaag gggtaaaaga aaataccccc
     3901 gaacagcttg aaaaagctgc ggaggtattc aaagagtatt tcactacggt agtagttaat
     3961 taatggagaa ttctccaatg acctcaaagc aagggcattc tttaatccgt tcccaaggat
     4021 ctacgatccc attatagttg gtgtcgggac ttaaatcccg atgccctact actttagctt
     4081 ccggataacg ctgcaacaat tcgtgtacca agcgatgtag cgcctccttc tgacggggtg
     4141 tacgcgtatc cgccgctttt ccattctcat ccagaccgcc ctcatagcat acacctaagc
     4201 tgatcgcatt gtagccacgt gcatgagctc cgaccgtatc ttcatcccgc atcggctcaa
     4261 tctcgcccga cttgcgtata taataatgat acccccagca cgaaaagcca cgataacggt
     4321 gagccgtatc cacatccttt gccgtaaagt cgcaatcgac acgggtggcg gaacaatgga
     4381 tcacaatcag actaatcttt ctcatgttcc ttttcccttt ccgtcgtttt cactttgcac
     4441 acctccttac aagtagtatg atagcgcact tctctcacca ccttgtcccg ctttctcttt
     4501 ccgaagaaag gaatcagata catgatcaca tctaaaatcc ggtttactat ttctttcatc
     4561 ttatcaaaat attaatggaa gttattctaa ttcgttatta ccttgacccg tctgccaatt
     4621 ataccgtagg gtccggagcc tcttcatcac cggagccatc accaccggaa tccggattct
     4681 tgtcagggtc ttctcccccg ccatcgcctg cacccgcctg cgccaccgca cgagtcagca
     4741 cttgctggta actcagaatc ttcatcaatt ccgccagcgt tttaccgggg cggaaaataa
     4801 gatgcgcccc cttaatcatc gaaccggaaa attccttgac cgatgccgca ccttcactgt
     4861 tcagtcctat ctgcaaactg cccaaatcac ccagtctcgc aattcttcct gccttcaacg
     4921 cacgcttcac ttcgtaaaga atacccgaaa tagccgcacg tacatccgtt tccgtacaag
     4981 tagaacgact ggtgatcgct tcgcacaact cttcaaagtc cagctcaccc gacgcctgcg
     5041 cctgtgcata atactttgcc ggttcactct tttttgcagg attcttgcgc ggcaccactg
     5101 aataagatac tgtcattgcc ataataaaat aattttaaag tttataatac gtaggatgca
     5161 tccctttctt gttaacagca caaagataag gatagccgga caagccatat tccccaacga
     5221 agtttcttga ttcccaacga ataaaaatga agtcaaacct ttgaaaaaca aggaatttta
     5281 tgtaacttta tagcataaaa caagaagaaa acatcatgaa ttacaaagaa gattctttcc
     5341 ttatccgcac ctataccaaa gcggaactgg ctcaccttta caatccccat gtctgcctca
     5401 aagttgcttt acaaatactt cgtcgttgga ttatttacaa cctccctctc ctgcacgaac
     5461 tcgaacagga aggctaccgc gcacgcaacc gtctcctttc gccgaaacaa gtggcaacta
     5521 tcatacactt tttgggcgaa ccgtagtaac ttattgccat tttatacaaa gttcctttac
     5581 acatttccgc aaagaagttc ctttgcatcg acaaacaata atcaaaataa aaatgaaaca
     5641 tttcaccata tttcaaggtt tctactacgc aatagcagag atgaccgaag aagaaatagt
     5701 gtccactatc ggcagtttta cctaccggga aaaagtcgaa gaaatacgcc gcatctttgc
     5761 agagcaagga gaaaaggctg ccaatgagaa gaaaaaagaa ttgccggcaa tcgccttctc
     5821 cgccagctac cgaggaaggc gtaccaaagt gaacctcgtc aaatatctgg gacacatcgt
     5881 gatagacatc gaccacctca gcaaagaaga attggcacgc atcctcccta tcatcaagag
     5941 atgcgattac acccgcatcg cctttatcag tcccaaaggg atgggcgtga aaatcatagt
     6001 gcgcgcatgc catccggatg agacattgcc cgaaaccctt caggaaatag aagacttcca
     6061 tcatgcagct tacaccagac tcgtttcttt ttacaccgaa ctctgtcgga tagaaatcga
     6121 cacctccggt caggatgtgg cacgcacttg tctgttctct tacgatccgg agatctattt
     6181 caatccgaac gctgacgctt ttcttgtaga tcaacctcag gcatcctaca agatttcaaa
     6241 tcgtaaaaat ctctccggca gtaaacaaca gactcctccg gacggcaccc cgacgaatga
     6301 agacacagca ctcaacgccc attccgccaa cgcttctttg gtgttgactt taacttacta
     6361 tcacaacaag tccgaaaaat acatagcagg caaccggaac aattatctgc accatctctc
     6421 atgtaccttc aatcgctacg gcattccgca ggaggaaaca tccgccttta tcaaaagcca
     6481 gtttacagac tttccggcgg acgagacagt ctctttgatc aatagcgcct acgctcatac
     6541 cgacgaattt aatacctgta aactgaatgg cacgcagaaa cgaagattac ggatagaaca
     6601 atatatcagc gagcactacg aaacacgcta caatgaagtg ctgcatatca tggaatatcg
     6661 cagaaggcgt cccgacaccg agaaaccgga gcctttccgc atcttggatg agatgatgga
     6721 aaacagtatc tggatagaaa tcaacgagct gggatatccc tgcactgtca aaacaatcga
     6781 aaatctgatt tactccgatt tcagccagtc gtatcatccc attcgcgagt attttgaatt
     6841 actgcccgaa tgggacggaa ccgactatat ccgtatcctg gcggatagtg tccagacgag
     6901 tcatcaggag ttttgggcgg aatgcctgga acgttatctg gtggcgatgt gcgcagcggc
     6961 tactcaggag aatattgtca atcacacggt acttctgcta tgcagcgaga tacagaacat
     7021 aggaaagact acctttatca ataatctcct gcctcccgaa ctgcgtgctt atctctctac
     7081 cggactaatc aattcgaaca ataaagatga tttagccaaa ataacgcagg ccatgctgat
     7141 caatctcgac gagtttgaag ggatgagcgg tcgggaactg aatgcattca aagatttggt
     7201 aacgcgcaaa gtgatcagtt tccgtctgcc atatgcacgc cgttcgcaaa acttccctca
     7261 tacggcctct tttgcaggaa cctgcaatta tcaggaagtg cttcacgaca cgacaggcaa
     7321 ccggcgtttc ctttgttttc atccttattc catccaattt attaccatca attatgcgca
     7381 gctctatgct cagatcaaat atctgctgaa taagccgggg taccaatact ggttcacgca
     7441 agcggacaat gaacggcttg aagagaataa cgaggctttc atctttcatt caccggaaga
     7501 agaaatggtt cttacgcata tccgcaagcc ggaacgtttt gagaaggttt attatctgac
     7561 tgtcagtgag attgcggaac taatacgtga gcgtaccggt tatcagtatt ccatcggatc
     7621 aaaaatacag ttggggaagg tgatgactaa gcaccatttt gaatctaaaa aaggaaataa
     7681 cgggcgccga tatgccgtat ttattataga tatcgagcag gtaaaatcaa acaggctgta
     7741 tgaatagaag cgggaaagcc ttgtgaatat agcaaaatgc agagtcatct tgacagatac
     7801 tctgcattta ttgtttttac aaaatcattg aaaattcgat tttacagcct aacgcattca
     7861 ttatacgata gaaagtagat actttaggct ctgtctgacc actttctact cttgaaatat
     7921 aagaacggtc agagccgata cgccgggcta attcagcctg agtgatttta gccttttttc
     7981 ttgcgtcctc gataatctgt cctgtataaa aggcgtaggc cttttcttct gcctctgcac
     8041 gagaagctgt tccttcctta ccaaaacgct catctattaa tgcactgaca ttaaagaatt
     8101 cctcatttgt ttttgcttcc ataatactcc tttcttaata tctttgcttt atcaatttct
     8161 ttctttggtg ttttttcggt tttcttttga aaaccgttaa acagaatcac aatacgccct
     8221 tcgtcgaaac aaaagaatat tctatatata ttgctttggt actcgatacg aagttcataa
     8281 agtccttctt ctatcaaccg cataaatttc aaaggtattc tgtcttgtgt ctgcaataac
     8341 attagcacat acaatatctt atcttgggtg ccagcatcta aattttcaaa gaattctttg
     8401 aagtatcctt tatatgctat tatttctctt ttcataacgc aaatataaga aatgttgttc
     8461 aactatacaa cacatttcct cgttttatat tatttttcat catcttcacc cacaaaagtg
     8521 agaggagtga gagaggaatt gaaacttttt ctattttatt tctttatttc tactttctat
     8581 atttctctaa aaaaaatacg aatgttagaa atcctctctc actcctctca ctttttacct
     8641 tttctttctc caaaaagacg gcgggaaatc ggaaaaacac aaccgtcttt tttcgatttc
     8701 tcaccgcatt ttcaaatcaa cccaccaatt gaagcagact tcaggaaata tttgttatct
     8761 ttgatgtgca aaagatcaaa agaatcagat atgggcaact tgatgcgtaa acttcctatt
     8821 ggaatacaaa cctttgaaga tatacgaagg aagaatatct tattgtaaag atcggagtgg
     8881 aatttagttc agaaagccgg aacttaaacc gttggttaat agagactatt gagtaataga
     8941 aacccaagtg gcggcaatct gcaacaagtt tccatccaga tttccgccac ttttttaatt
     9001 caaccgttca gcgatggaaa cagattattt aaaatctccc tccgaataat ctgaaaactc
     9061 cccggcacgt tctttcttct catacgagac caacgtttcg atactaagcg ctttcccgtt
     9121 cttagggctt atgacatcta tcacacttga caaggaccgg aacgtctgtt cgcaattcgc
     9181 gtctccatta tacgtcaacc tcccccggtc aatagcacct agaatgacag aaatgtaccg
     9241 tttcggatct ccccgatatt cgataacagt gggcgtcatt tgttcttctt cccgaatcag
     9301 ttggacgaca attctttttt ttggtcaatc agctccaaca gtttttcact atgcacactg
     9361 atttgtgcat ctacttcacg aagttcattc ttcaatgaac aaaacaattc atcactcaat
     9421 gaattttcca taaaaacgat ttttattaat tataaaaaag ccattccgga aagcacagct
     9481 attgcctgct tcccgaaatg gtgactaata ccttcaaaaa caatgactct atttttactt
     9541 taatgtactc aatttatttc acttcttttc tctcctgcat tccaaaccaa caaagcaaac
     9601 actactgaaa gcaaggctgc accaatccaa aaccaattga tatatgtaaa atcgtaaact
     9661 tctactccat tttgcaccgt cttctgacct tcgatcagaa tgccactcat cacatcctgc
     9721 aaaccggctc ctatataact cgctataccg acaactccca aagcggctcc cgaagcattg
     9781 cagggagcaa tatcgaccgc catcagtcct cctaaaaaac aaatcagcac tccaatgccc
     9841 aaaccgaaga gcaccatcgc caaagcatcc acccaaaaat gtacccccgg aaccaataga
     9901 aacaaacaaa tagcagacac attcattaat ccgaatatca aagccggaac attacgactg
     9961 ccagcaaaaa acttatctga aataatacct gagaaaaccg tacctacaat tccgcataca
    10021 gaactgatag atataataaa actagcatcc aaagtagaat aacctttttg cgcttccaga
    10081 tagaaaacac cccagctatt gactgcataa cggctgatat acataaaagc actggataat
    10141 gcaagaatcc aaatagcagg attcttcaaa actgctttct gagctttatt gaattcctcg
    10201 gtttgtttac cggaaacgga atgagcatct gacgtccccc gccgatctag caaaaagccc
    10261 tgactttgag gcgtatcacg cataaaagca agcatcatca gaaaaccaag caaaccaatc
    10321 actcccgcac cgatcatccc ataacgccat cccatccaac tgaccagcaa agcgatggat
    10381 ataaaagtca gagcttcacc caaattgtgg ctggccgacc aaaagccata aaaagtacct
    10441 cgctctttac tactatacca acgagtcagc gacacaactc ctgatgctgc ccccatcgac
    10501 tgaaaccaac cattcaaccc ccaaaggaga acaaaagcaa agaaggaatt cgtgaatccc
    10561 agacataagt tgatcagagc agaacacaat aatccggtag acataaaacg ctttacattg
    10621 ctacggtcag caagaaagcc attggtcagc ttaccgacgg catatacgaa aaaaaggcag
    10681 gaaccgataa tccccagttg ggtttcggta aaaactccgt cttctacaat cggtttacgg
    10741 attacattca tactcaaacg acaaacataa taaatgccat atccggtagt ggcagacaga
    10801 aaggtagccc aacgaatacg cttgaaacgg acagagcgtt ccgaatcagt ctctcccccg
    10861 gacaccggag gagagatttt ataaaaatcc aatagtttaa atcccataaa gaagtctata
    10921 ttttaatgat acgcatcttg cccgttttca ctacgcttct tacgcgattg caaatattcc
    10981 agcagatagg cagtacggtc tgtctgaatg atggccgctc cgagtgtatc gatcagataa
    11041 ccatatcctt cgtccggatt ctccaacgat ttatcatcat catgtccgcc agccatcgta
    11101 tcccacaacg tattatacca gattttactt tttcctttca acttcgtttt tacttgcttg
    11161 gggacctggc aggtatccga tacaaataga agttcaaaag ctacgggatg cagctccgtc
    11221 ataaaatcat ccagttgctt cattgctccc ggcttatcca aatgaatgat aggcatataa
    11281 atgatacggt ccagatattt acctaagtcg ttctttacgt ctgccacagg cttggaacct
    11341 ttcatgataa tctgatccac tgttcccgtc ttttcgagga tggggaaaat ctcgtcaaat
    11401 atcggatatg ctttatccag attgaccatc acacgacctt tggcaaccca taaagcctct
    11461 tccaaagtag gtacacgatg cttggttttg agtgccgctc cattcttcag atagagtgtc
    11521 cggatagaat ccaatgtcca ttcggctacc tttccttttc cggtagtcgt tcggtccagc
    11581 gttttgtcat gcatcaggat caattgaccg tctttggttt tctgaacatc cagctccact
    11641 acgtcagctc ccagacgaat ggaactttca atagcggcaa gtgaattttc gggtgcgtaa
    11701 cgccagtctg cccgatgagc tacaaccgtg atttctttat tgtcagggtt cgttatcttc
    11761 gcataaatgg ctttcaccgg ttcgtctgcc gacaggcaga aaggaaatgc gaataagatt
    11821 cctatcatta tatatttctt catatctata tgtactatta tctgtatcct ttagacttta
    11881 aatatttggc agctacttca gcatagtctg tttgcacaat gttgatgcgt ttgttaatca
    11941 ttcccaccaa accggagtag ttttccgaca acatattggt atcattcgct ccgacaatgt
    12001 tggagaaaag aagccagcct tgatctttaa tctcattaac catcgttcca cccatagcgt
    12061 ctgacgtaga cagctgcatc atttgtacat tatcagtgta ggatgaggag aagtatgtga
    12121 tatcatcggc ggcttttgcc atcgggtgca acagcaaact actgttggct gtcttcaaat
    12181 caaatgcata attgcgattg ttggatacat acagcaaagt ggaaccttcc atatccaatt
    12241 ttttaagcaa tgcgacgatc gtatttaccg caacattctt gttgacaata tccagattat
    12301 aataaacttt tccttttccc ttcttcatcg cttcctccaa agtcgggatt cgttcgccag
    12361 ttatattgcc ggatgcatct ttcagataaa attgttgtaa ttgctgataa gtaaagtctc
    12421 ccaccgcacc gctaccgttt gttgtccggt cgatggtgtt gtcgtgcatc aataccaaca
    12481 caccgtcaga ggtcggccgt gcatccagtt cgatcatctc aactcctgct ttgaccgagt
    12541 gttctatcgc aggtaacgag ttttcgggaa tcccctcttt catccctttt tgggtatttc
    12601 cacgatgcgc gcagagccac actttataag aggtgctttc aaacagactc tttaaatctg
    12661 ctttcaaatt ccccgtcata ggcaactgtc ctccttcttc tccaccggga ttctctccat
    12721 tccctcccga ttgggctccg gagtgacgtc tgtccttccc tttcatcggc caggcagagg
    12781 ttgcggcccc ggtaattccc tcatcttcca aagctactaa cacgctcttt gtagggtcca
    12841 ccgtattggt gactccgata taaatcgctc catccggtcc gatggtaggc gaactccaga
    12901 ttttaccgat tcccgcttcc caatctcctt ttaaaggaga gtcactttca ctaatcaacg
    12961 cagcaaggtc ttttttcaga atcaattgtt catccgattc ttccggttta atgatataat
    13021 aattgccgga ctgggtgccg aaatgtatgt ttcctgcttg atcaattgcc gcacaaccgc
    13081 ttacatcttc cgcaatgccg taatgccatt ggatagctcc tcccggagac aaagagatga
    13141 ttcctccggt tgcttccccc ggagcacgtt tcactgtaac gataatgctt ccgtcgagtc
    13201 ctatcacaac accgccttga tccagcgtgc cgacattgcc caaaggagta cgccacttct
    13261 ccactccatc acttcccata gcaaatgcgc tacttcccat tcctgcaaac gtagctgttc
    13321 cgtaaatagt accagcctca tctactgccg gagaaccgtt catattttct gacggcttat
    13381 catcgccgga gctaaatacc tgccaagccc acattacatt tccaccggca ttcaacgcag
    13441 aagcagaagc cccgaacaat ccattctttc cgccacccca aactaaagtg ttgtttgcca
    13501 atactattcc ggcagatact cctccggaag gacctccgga attatccgca ttcgctacgt
    13561 atcctacccg atagccggtc accttatcta ctgcaagcac tgatcctgta gaaccgccat
    13621 tacccatata tacatgattc tcaccaatgg cacaggtcag gtaattgata cggggtgtgg
    13681 aagcgtttcc tttattccag aagccctttt cagcgtcacc tgccaccagc catttcttac
    13741 tcccgtccgg atttattgca tacacacgtc ctactttgcc actggtgtct cctgttccta
    13801 cgtagattgt tccgtctata tcaatgcttg gagtagtatg cgtatttccg gatggtgcat
    13861 cgccgtcagc agatgtccaa aggtcaaatt cccaaagctg gtctcctgtc gctgccgaaa
    13921 atttacgtaa ataatgatca ttggaagtca tatacacccc att
//
