LOCUS       gnlProkkaIFNJLDFB_75   13621 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IFNJLDFB_75.
ACCESSION   gnlProkkaIFNJLDFB_75
VERSION     gnlProkkaIFNJLDFB_75
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:52:27
            Original ID  :: gnl|Prokka|IFNJLDFB_75
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13621
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13621
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3270:3621]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3271..3621
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13621
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13621
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             279..1790
                     /locus_tag="ctg60_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             1863..2930
                     /locus_tag="ctg60_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVSKKVAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKELNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             2968..3252
                     /locus_tag="ctg60_3"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3271..3621)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_4"
                     /sec_met_domain="PqqD_RRE (E-value: 1.8e-10, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.4e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(3719..5107)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg60_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5356..5751)
                     /locus_tag="ctg60_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(5758..6531)
                     /locus_tag="ctg60_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6537..7064)
                     /locus_tag="ctg60_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7051..8292)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg60_9"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8302..9396)
                     /locus_tag="ctg60_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9401..10441)
                     /locus_tag="ctg60_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(10460..11494)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_12"
                     /sec_met_domain="PF04055 (E-value: 3.3e-17, bitscore: 57.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
ORIGIN
        1 aaaccgtcga aataaaaaag agattaccac caaatttgac gaagaaccag aaatcttttt
       61 caggagaaat aaaagtaagt tcataatggt gctgcattga attatttttt ggcggagtta
      121 ttctaacact taatagttca aaagcagata tttctctgac ccaaagatag aactaatgat
      181 gaattaaaag ttgcaattat ggttttcttc ccacaacaaa cgggaaaagt cagaagaatc
      241 atgtacattt gtaatccgaa aactaaaaga acatcgcaat gaaaatattt ccaagcagca
      301 gtatcaagaa attggacgct tataccattg agaacgaacc tattgcatca atcgatctga
      361 tggaacgtgc agcaaccgta ttaacaaaag ccatcacaga cagatggaat acggaaacgc
      421 cggtcactat ctttgccgga ccggggaata atggcggaga cgctctcgcc gtagcccgca
      481 tgatggctga aaaaggatat aaaatcgagg tatttctctt caacacgaaa ggagaacttt
      541 cacccgactg ccagaccaat aaagaactgg tagaaatgat ggaagaagta aaattccacg
      601 agatcagtac ccaattcgta cctcccgccc tgacgcccga ccatctggta atcgacggat
      661 tattcggttc aggcctgaac aaaccgttga gcggcggatt cgctgccgta gtgaaataca
      721 tcaattcctc ccctgccatg gtagtagcca tcgacattcc ttccggactg atgggagaag
      781 aaaacacatt caacgtaaaa gctaatatta tccgtgccga cgtaactttc agtcttcaac
      841 tgccgaagct cgcctttctt ttcgcagaga acacggaatt tgtcggagaa tgggaagtgc
      901 tggatatcca attgagcgaa gacggtattg aagaaatgga gactaactac gaaatgttgg
      961 aaatagagca aatccgttca ctcatcaagc cacgcaaaca gtttgcccac aaggggaact
     1021 tcggccatgc actattgatt gccggttcaa aaggaatggc aggagcctct gttctcgctg
     1081 cccgcgcctg cctccgttcg ggagtaggat tactgactgt tcatgcacca atgtgcaaca
     1141 acgacatctt gcaaacctcc atacccgaag caatcgtaga aaccgacatc aacgaaacct
     1201 gttttgccgt acctaccgac acggacgact atcaagcagt cggcatcggt ccgggactgg
     1261 gacgaaacga ggaaacggaa gctgccttgt tggaacaact ggaacactgc cagactcctg
     1321 ttgtggtgga tgccgacgca cttaatatcc ttgccaacca ccgccatgcc cttacccacc
     1381 tgccgaaggg ttccatcctc accccgcatc cgaaagaact ggaacgtctg accggcaaat
     1441 gccaggactc ttacgaacgt ctgatgaagg cttgcgaact ggcccgtgcc gcccatgttc
     1501 acattatttt aaaaggagcc tactccgcca ttatcacccc cgaaggtaaa tgtttcttca
     1561 acccaaccgg aaatccggga atggcaaccg gaggtagcgg tgacgtactg accggagtaa
     1621 tcctggcact gcttgcccaa ggttacccca ccgaggaagc cgctaaaatc ggcacttaca
     1681 ttcacggact ggcgggcgat gtcgctcaaa agaagcaagg aatgatcgga atgatcgcaa
     1741 gcgatattat cacctgtctg ccgacagcat ggcgacttgt aagcgaataa aagttaagaa
     1801 cttacccttt tttcaataac ttcattaact ttgttttcaa aaccagttaa aaagaaccga
     1861 atatgaaaaa gttgattata gcagcaggac tacttatgac aacgtccgcc tatgcacaaa
     1921 ccgaagtact gacgggggtt acccgaggaa aagactatgg agtggtttac agtcttccca
     1981 aaacccaaat agaacttgaa ataaaagcca acaaagtcaa ctatactccc ggagaattca
     2041 gcaaatatgc tgatcgttac ctacgactga ccaacgtctc cgccgaccct gaagagtact
     2101 gggaactggc tagcgtaaaa gtgaaatccg taggtgtgcc caacagcgaa actacgtatt
     2161 tcgtaaaatt gaaggataag acagtagcac cgctcatgga actgacagag gatggcattg
     2221 tgaaaacgat caatgttcct tacagcaaca gcagtgtaag caaaaaagtt gctcccgccc
     2281 ccgcagtcct ccaaaagaaa gcgaatcctc gcgaattcct gaccgaagag attctgatgg
     2341 ctagttctac cgccaagatg gccgagctgg tggctaaaga gatctataac atccgcgaaa
     2401 gcaaaaatgc cttattgcgc ggacaggctg ataatatgcc ttcagacgga gcacagctta
     2461 agattatgct cgacaatctg aatgcacagg aagaagccat gacgcaaatg ttctccggca
     2521 cctgcaacaa agaagagaga acattcactg tccgccttac tcctgacaaa gaactcaaca
     2581 atgaagttgc cttccgcttc tcgaagaagt taggtgtagt tgccaacaat gatttggcag
     2641 gaactccgtt ttatatcagt ctgaaagacc tgaaatcggt caagatgcca caggaagatg
     2701 gtaagaagaa gaaagatttg gatggaatcg cctacaacgt acccggacaa gctatggtta
     2761 cactgaccga cggtaaaaag aaactttatg aaggtgagct tcctattact caattcggtg
     2821 tgatagaata tctggctccg gttttgttca ataagaattc taccatcaaa gtttattttg
     2881 atccgaatac gggaggattg ctcaaagtgg acagagaaga agggaaatag aaaaacgaag
     2941 gaagtgaact tctaaaaaac aaagaatatg gttggtgaag gacatgcatt cgacatgata
     3001 cgccgaataa aagagggacg ggaagcttcc cgcctacgtc gtgaacgtgc taacgataag
     3061 ttgaagcatc taaaccgtgc aaacgaacct tatccactac ccaacaccac ccccgaagaa
     3121 atggaacgta tcatccacga ctcggagaaa aagaaagaga aagacagcaa ttattttgtt
     3181 tggggaacgc ttattatcat gggggtcctg atagcaattg ccgtcatact ttgggctgta
     3241 tttatcaaat aaataataat aaattcctat ttatgcaact ggtatcacca gttttataaa
     3301 tccatctttc tgcatttgag aaagataagc cgatacacgc gactcgtagc cctcttcatt
     3361 ttgaaagtgg tctgcgagtt tttctataat ctcacgaaca ttgcgttttc catctatcag
     3421 ttcccataca gccgtaccgt gttcttccaa tttcacatga agttctttcg acattccttt
     3481 cggcacaagg aagcgttgca tccacggata tttaaaacgg ggaaaggaga gcacaattgt
     3541 ctccccttcc ctttctgctg taatatgttc actgcgacag ggaatgacct ctaacaggtt
     3601 gattttctct ttggcagcca tacttcttat tttttatttc agagtattca tactgatacc
     3661 cttttgttta caccttgata caaaattcct ttgttacttt aggtattgaa tttcccagtt
     3721 acttttgaat attcgcctct tccagaccgt atcccttctt cttgttctct gcctttaaca
     3781 tcaaagccac aatcagagca agtacaccaa aaagagcaaa aatagtcatc ggcaacgtgt
     3841 agtcataagt ctgtgcaccg tctactaccg gacctttgca ataagtattc aacacccatc
     3901 cgatcaacaa aggaacaccc atcaatcccc agttctgtac ccagaaaatc aatgcgtatg
     3961 cggtacccaa ctgtttttcc ggaataatct tcggaacaga cggccacata gctgaaggca
     4021 ccaacgagaa ggcaaatccc aatataatca tgataatagt agcaaaccac catatattca
     4081 gtataggcag agcaaacatc gtatgcacaa aaataagcat cactgatccg attatcatca
     4141 atgtggctcc cttaccaata cggtcataaa gcgagccgaa caacggagtc agaataatcg
     4201 caccaatcgg caacaatccg ggaatcgttc ccgccaactt cggatctaca ttatacttct
     4261 gcaccatcaa gtcggcagca tacttgataa aggggaatac agccgagtag aacaatacac
     4321 atagtaatgc aatcagccag aatcccttat tcgtaatgat atacacaata tctttcatac
     4381 ggaacggctc ttccggctcc aatccctctg catccaaaga agcatccaac ttcttatcat
     4441 agaaagtata aaggaagaaa gcaatcgtac ccacgcacaa cataatcaga caaaacaaaa
     4501 tcggagcagg aatattggta tggaatgtgc cactctcatc cgtagatccg aaaaagtcgg
     4561 ccaaaggaac cgtgagcacc attgccagag ttgttccgat acgtgccgta gccatttcaa
     4621 gtcccatagc caatgccatt tccttaccct tgaaccattt tacgataatt ttggaaactg
     4681 tgataccggc aatttccaca cctacaccga agatagcata ccccaatgcg gccagggtta
     4741 cctgtgtttt gaatccaaag agcatggcac cttccggaaa agtagtagaa atcgcatagt
     4801 atttcaatcc acaaccaaac accatcaata agcaagcccc cattccggtg aaacgaactc
     4861 ccatcttatc caaaatgata ccaccgaaaa tcagcatcaa taggaataca ttaaaccacc
     4921 cgtaagcgct tgtgaagaaa ccataatcaa gactgtccca tagtagttct ttctcaagca
     4981 tgggttttag aggagacatt acgtcggtga ggaaatagcc gcatagcata gtaaatgcga
     5041 ccaatgctag aacactccat cggagtacgg cggagtcatt caatttctgt ttcaaatgtt
     5101 ctgtcattgt tatatttaaa aaagtagtta ataatcttca tacgaccaac aaaggtagtt
     5161 aaatctcgtt tgtttctatc aaaaagagat tgtttttaca agaaaaagtt aagtgcggat
     5221 tacactgacc acgcggaaga ttgaaaatcc gtgtaatctg cgtaatccgc acttaaatat
     5281 caaagaaatg cagcatccgt ctgcaccttc ccattaatgg ttttacccca aagtcttacc
     5341 tgacaacgga gtgaattact ctgctgcagg agcaggagtt tcagtagcag gtgccggagt
     5401 ttctgtagca ggtgcattgg tagcaggagc ttcagtttgc ggcgcagccg tacctgcggg
     5461 taagttatac gggttagtct gttgttcttt ctgtgcctgt tccaacactg cgtctttagc
     5521 aacagcagag cgaggaacta cataagcagt agcaatgctc attaccacca tgaagatagc
     5581 taagccccat gttgcttttt ccagaaaatc tgtagtcttg cgcacgccca tgatggcgtt
     5641 agatgaagag aaaccagaag caagtccgcc tccttttgag ttctgaatca gcacgatgaa
     5701 acacatcaac aaggctgcaa taaccattaa gataacgaat aataagtaca tttttagtta
     5761 ttttgaatta gcgttaataa tcaatttctc caaaaatctg atttggtctg caaagtaagc
     5821 attttttttt ggatatttca agcttaattt tttaattatt tcaagagctt ttgaatatcg
     5881 ttgctgttta acatagattt ttgccaaagt ttccgtaaaa cagctgtcat cttcctcttc
     5941 ttccttcatc gtttcttctt cggtaagttc gtccgaagag gttggcgaag atggcatttc
     6001 ttctcttaaa ggtttcttgc agaggggaga gtcgctctcg ctcttttcta taaagtcgtc
     6061 aatcagttcg tagcctttga gtttgggcgt ttcttcggcc gactgttccg tggccggagt
     6121 ctcctccaaa agataagagg tgtaatccat cgaatagtcg aagctggtgc gggcagtcac
     6181 ctcttcgggt actgtggaca agaaagcgtc gatcaatgct aatgtgcggt ctacggacgg
     6241 ttcgtctttc agcacctccg tgagaggtac tccctttttc cgtgcctgca catcatagcg
     6301 gtcaccttca atcaaccgga acaactgccg tctgtctgca atgtaaagaa ctgctttccg
     6361 cagttctcca ccgaaactaa tatcatggag aatatacaga ttcttcagat acagcagacg
     6421 aagtgactga aaatacggat acctcgcaag aagattgcgc agttcgtaca aagtatccct
     6481 attcagcgtc tcgggatgct gaatccattg ttgaaagtta acagaagtca tttatattac
     6541 cagtttgcta cagttgcatt aaaaatttgg tcggtgatct ctttagacat ttcagcaatc
     6601 aatccgtcct gtacggcagt cagcaactgg ctagagtcgt aggtacggaa cgcagaaaac
     6661 tgttgttcaa agtcttcggc atgattggtg ttgttgacaa aacgtacatt gacggtaata
     6721 gtcaacttcg tctccgaaga gtaaccgtcg gcagatactg cctggttgta ctgattgtat
     6781 cctgtgattt ctccgtcaat ctgcaagtcc gcattctgat tcggcttgag cagttgcaga
     6841 cgggtctgcc ggatgaagat atctttcagg tcctcattga atttggttgc taacggagca
     6901 tatacatact ccgacttgat cgggaagtcg gctatcgaaa tggtctttac cttatcataa
     6961 ttgatagacg atccgttaaa cttataggaa acagtgcacg caatgactac caacggcaag
     7021 ccgaacagta acaaagggcg tattattttc ttaatccaat tcatattctt ttatttttct
     7081 ataaagtgta cgctcggaaa tattcaagtc cttggccgca ctcttccgct ttccatgatg
     7141 cctctcaagt gccttgcgta tcatttcttt ctccacttcg tccagtgaca aaggggattc
     7201 ttctacatat tcttccgtgt cttgtatgtc atcatcatcc ttgcaaaccg taggctgcat
     7261 ggtgtgaatg atagcaggta ccgaaggttg atgcgccgtc actaccggag tagtaaccac
     7321 cgttcccatt tgtcctacct gccccacctg tccggcacgt tccgccatca ggttgtgcac
     7381 catcttcttc agctccgcca cttcctggcg catatcgaac agaacagaat aaagaatctc
     7441 ccgttcgctc tcaaagcctt tactctcacg cgttcccatc aacgcgggaa gacgttgcgt
     7501 attttgtgca ggaagataat tctgcaagat agcagcagag atctccctat tggtttcaat
     7561 gatagatatt tgctcggtga tgttcttcaa ctgacgcacg tttccgggcc acgggtaagc
     7621 caacaactct ttcttcgcat cctccgtcaa ctgaatagcg ggcatccggt atttctctgc
     7681 aaagtctgcg gaaaacttac gaaacaacaa aagtacatcg tcaccacgtt cacgcaaagg
     7741 cggtatctgg ataggcaccg tattcaaccg gtaatataaa tcttcacgga aacgtccttc
     7801 tgcaatcgct tgtgtaagat tgacgttggt agccgccacc acacgcacat ccgttttttg
     7861 tactttggac gaacctactt tcataaactc gccactctcc agtacacgga gcaaacgtgc
     7921 ctgggtagac atcggcaact cccctacttc atcaagaaaa atagtaccac cgtcagcttc
     7981 gccaaagtac cctttccgtt cgccaatcgc accggtaaac gcacctttct catgtccgaa
     8041 cagttcggaa tcaatcgtac cttccggaat agcgccacag ttgacagcaa tatactgtcc
     8101 gtgcttcctc cggctatatt gatgaataat ctgcggaaaa ctttcttttc cgactccact
     8161 ttctccggta atcagcacag acaaatcggt aggagctacc tgaatggcaa catctatggc
     8221 gcgcgacaat gcttcagtat ttccaataat accgaaacgc tgtttcactt gttgtatctc
     8281 tgctttcgtc atcactcgtt tttaatcttc gtctactgta tccagcttca gtttatcact
     8341 atcgtcacgt ttctcgtaat actgtttacg caacggattg gcacgagcca ctttttcccg
     8401 ctgacgatta cggaacacgt cgatggcaac atagattgcc tgacggaaag aatcttcaca
     8461 agccactccc ttgcctgcaa tatcgtatgc cgttccatga gccggagaag tacgtactac
     8521 cggcagtcct gccgtatagt tcaccccgtc ttccatagcc aaggccttga acggagccag
     8581 cccttgatcg tgatacatcg ccaggatacc gtcaaaatga gtataattgc ccgaacccat
     8641 aaagccgtcg gccgcataag gaccgtagca aaggattcct ttctcttcca tttctttcat
     8701 ggcagggata atcacttcct gctcttccat tcccaacaaa ccaccgtctc cggcatgagg
     8761 attgagagag agcaccgcaa tacgcggagc gccgataccg aaatcctgtt tcagacaacg
     8821 atggaatatc atcagtttct cctgaatcaa ttctttggta atcgtagtcg caatctctct
     8881 aacagggata tgtgtcgtca ccaaagccac ccggaagtca ttcttcatca aaatcatcaa
     8941 tgacttatca ccattgccca gacgttcttc gatatattcc gtatgtccgg ggaaggagaa
     9001 ctcttccgac tgaatcgtat gtttgttgat cggagctgtt acgataacgt ctatcaaccc
     9061 ttcgcgatat tcttcgatgg cacgttccaa agcccccagc gcagctttac cggcttcggg
     9121 gtcgggtttg gaaaattcca ctttcacctc atcatccgta cagttcacca cgctcaaacg
     9181 gttgtacccc gcttcggtag cagagttgac aatgctgaaa ttggcctgta tatccagtgc
     9241 tttgcgatga taagccgcta ctttcggtga gccataaatg atcggagtac atagttccaa
     9301 catcgtaggg tcggaaaatg tcttaagaat cacctcatag cccaccccgt taatatctcc
     9361 ttgggtgata cctatcctta tcttgttatc ttccatgttt ttatttatta gtttgttccg
     9421 cttccttaga tgcttctccc aatggaatct gcttctgctg aacttcattc ggaagtttca
     9481 gtgtatacag agatgcttcc atctggcgta ctaggttgcg tttcatttta tcaggtgaat
     9541 aaacaaatat ttctgcagta ataattcgtt ggttcttctc gtccagacga gtatgagata
     9601 catacggacc acccataaag tcgcccttca tacgccacag accacgtgct tccattgtgt
     9661 agctgttctg tacattgatc ggacggacat cggtcagtaa actatcggtc gacatataaa
     9721 ctccttcctt gaatccgggg atattggctt tcatcacaga gtcacgtttg tgcacaaaat
     9781 attctttggt aaacgtatcc ttgtcagtgt acggataaga gtacatcaca aagttacggt
     9841 cggcagtacc tgtgttggta gaagcccaga agaaatcatc cccggtcttt gaattagcca
     9901 gttcggcatc cacccagatg tcgcatccga acaaactgtc cactttctgc gaaatgaaat
     9961 tactgtgttt cccttccagg aatgtaatct gacggttcat ttccgcacgg gtaaagaagt
    10021 cgacaatcgt ctttttgttc tcttccacaa acttctcgaa ctcttcttcg ttcggagcct
    10081 ggatagtcaa tatcatctgc ggattggcat acacgtcctt cgcatatttg aacgaggctt
    10141 tcgtatatat atcctgtata tctacaataa taatgttacg tatcaacttc agcgtagaat
    10201 cataatcttt cggcgaagta tacataatcc ggaaagaagg ttccgactgc ggcaaaccgg
    10261 gcatatcagc atcgagcgca tcatgtaaag cccttccggc agcacgatcc caaacaccgt
    10321 gatctactac aaccaaaagc tcgtaagcac gaccactaga ggtgtgattt cctttcagac
    10381 cacaagatgc aacgacaaag gctaccaaag cgatgcataa aataaaagag tactttttca
    10441 tgatgttcgg ttttatatat taactttcat tatttttctc ctgtttcgct gtcgacagca
    10501 taccgcaagc ggcaaaaata tcttcgcccc tggatgaacg gatagtggtg aaaagtccgt
    10561 gtgacgtcag ataatcacga aaacgggtca tcgtatccat gtccgccccc tcgaggtcta
    10621 cccccggtat ggcatgaaaa cgaatcagat tcaccctgca atccagcccg cgaagaagtt
    10681 tcagcaactc tttggcatag acctgcgaat cattgagccc tttaaaaaca atatattcaa
    10741 acgaaagtcg acgttgttta ctaaaatcat agttttttaa cagttccacc atttcggtga
    10801 ttgaaaacgc cttttccgcc ggcattaatt cagcacgctg aacggtcagc ggagagtgaa
    10861 ggctgatggc aaggtggcag tcattttctt caataaaacg ctgcaatcct ttccgtagcc
    10921 cgactgtaga aagcgtgata cgcttcggac tccatgcgta accgtaggta gcggtcagta
    10981 gttccaatgc cttcaatacc tcatccaggt tatcgagcgg ctcgcccatt cccatcatta
    11041 cgacattagt cagtttgtcc cgttccggca gcgaatgaat ctggtttatg atctggctgg
    11101 cggtcaggtt agccgtatac ccctgtttgc cggtcataca gaacttacag ttcatcttgc
    11161 aacctacttg tgacgacacg cacaacgttg cccggtcatc atccggtata taaaccgact
    11221 ctacaaaatg gttctcaccc actttataaa gatacttcac cgtaccatct acagagcgca
    11281 tttcatctac cggagcttcc gctcccacct catagttctg cttgagcaac tcccggtgtt
    11341 tcaatgacaa attagtcata tcatcaatcg aggctacctt cttttcgtaa agccaggatg
    11401 caatctgctt ggcagcaaag ccgggcatac ccagtctttt tgtcaatgat tgaagctcta
    11461 caagagtcat tcctaaaagg ggatatttag acattcttct ttctgttgat agtttatatc
    11521 tgcaaatgta aggaaataaa gtcgatttcc gtatagcagg aatgtaaaag ttaacaaaaa
    11581 agggaagtat acccaagtta ttatttaaca aagctgatat attgaagtag cgttcgcgcc
    11641 aattcagagt cctcgccatt ccgtttcact tcgtgaccat acgcctcacg gaaacaagcc
    11701 agcgcatctt tccgttcata acaatatttg tgtaaaaccc ctaagttttg acaagccaca
    11761 atcgtatctt cattctccca tccctgatgc ttctttcgca gttcaaactc tttgaagaaa
    11821 gccgctttcg ccattggata atccttcttt ttcgtataag ccagtgcttt gtagtaatat
    11881 accagacagg aagaatcggg gtcaccatca tcatgaatat ccagggaggt tgctatacga
    11941 atcacattat cataatcttt attcatgtaa tattgctgca taatatcaca tcttaatgcc
    12001 tcgtaacgga tagtcaattc tgccaaacga ggcttttcgc tgaaaaacac ttcatgcaga
    12061 agagactcat ggaagaataa agtagcggcc tgctcatcgt tacgctcatt cattatgcgt
    12121 ttgaattcta tgcatagata atacaactgt ttatgacaag cgactatctg ctttctatta
    12181 tctatctgca tagaaatatc caatgcccga ttcatcagat tccacgcttc atcgtattgc
    12241 ttaacacaat aaagacatct accttgcata cgcatgcatt tagccactcc acttgacaat
    12301 ctaccattca aagattcgtg cattttagct actttccgga attgttcggc cgcactctct
    12361 tcgtttttct tataataatc gcaataagcc agcagttcgt aaagttcaat gatttctgcc
    12421 atattattct cgtcagtaga agccgcatga tagccaagcg ctctatttag ataagtcacc
    12481 gcttcattat attgcccatt ataataacat gccatcccca aattcctaca tgtatcagta
    12541 atctggggta ccggaatcgg tactatattt tcctgcatca tcaatgcttt caggaaacaa
    12601 tcacatgcca tttcatattc ttcgtcacgg gcatagcgac atccctcgtt cattttcagc
    12661 actgatctgg caattggcgg tatggcagct ccttccatac atttctcact cacaacattt
    12721 gctacctttg tcaggtgaaa agaacgactt aagaaagtag ctatatcatt agcaatgaca
    12781 ggaatcaaaa aagaatcaac ctgaccaaag tccgattcgg catagacatc aggcataaaa
    12841 gaagagtcgt cgctcataag tgccttccag caatcttcca acaaagaata attcgtacga
    12901 tacagaattt cgaagagttc tacatcacaa atccactttc tcaagaaatt ccgctcctgc
    12961 atcttataac cttgataagt aatttccact ttatagcgat aagaatcatg gtagcagaac
    13021 tgtttcatac gatagctata atcagcaaaa gtcagttggt gcgaaaggat atcttcattg
    13081 tccagaagag aggttattat tttatgacga cacttatcga tgcacatatc gccttgagcg
    13141 aagcatcgtt taatcgcctc taccatttgt gtgtcacaaa tacaatatcg ccctcctttg
    13201 ttggtgagcc agctactcat ttccactttc aactgtgacc aaagcatctg atttatgcct
    13261 gccatgctct ttacttcatc ttcggtaaat ccttctaaag taagtgaaag catcagaagc
    13321 gttcttccaa tctcttcgaa accataatca gccgacaaac gccgaagcac actgtcataa
    13381 aattgctcaa cctcattgag ccggcaatat ccactcatat attcatagag agcatcgtac
    13441 tgaccgaacg aaaccagctc attgagcaat acacttaaac agcgcggttg tttagccagc
    13501 acccacgaac caagaatatc ttcctgctgt gcagacaagg tcttggagta agcagacaaa
    13561 tattgttttg agaactcctt agcatccact tgtgaaaaac cattcaactg gaaatgaacg
    13621 t
//
