Select genomic region:
Overview
6.1
12.1
12.2
17.1
21.1
32.1
61.1
78.1

### Identified primary metabolite regions

c00006_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_6)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 6.1 | Oxidative_glycerol | Other | 35,148 | 72,557 |

c00012_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_12)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 12.1 | Others_HGD_unassigned | Putative | 25,145 | 49,383 |
Region 12.2 | acetate2butyrate | SCFA | 136,169 | 152,775 | Acetate to butyrate C. sporogenes | BUT | 100%

c00017_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_17)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 17.1 | succinate2propionate | SCFA | 21,605 | 46,577 | Succinate to propionate B. theta | PRO | 25%

c00021_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_21)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 21.1 | Rnf_complex | E-MGC | 29,546 | 46,875 | Rnf complex C. sporogenes | RNF | 100%

c00032_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_32)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 32.1 | OD_AA_metabolism | Putative | 8,133 | 31,393 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%

c00061_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_61)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 61.1 | Pyruvate2acetate-formate | SCFA | 1 | 7,070 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%

c00078_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_78)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 78.1 | pdu | SCFA-other | 4,499 | 46,294 | Propanediol degradation S. enterica | PDU | 54%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 6.1 | Oxidative_glycerol | Other | 35,148 | 72,557 |
Region 12.1 | Others_HGD_unassigned | Putative | 25,145 | 49,383 |
Region 12.2 | acetate2butyrate | SCFA | 136,169 | 152,775 | Acetate to butyrate C. sporogenes | BUT | 100%
Region 17.1 | succinate2propionate | SCFA | 21,605 | 46,577 | Succinate to propionate B. theta | PRO | 25%
Region 21.1 | Rnf_complex | E-MGC | 29,546 | 46,875 | Rnf complex C. sporogenes | RNF | 100%
Region 32.1 | OD_AA_metabolism | Putative | 8,133 | 31,393 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%
Region 61.1 | Pyruvate2acetate-formate | SCFA | 1 | 7,070 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 78.1 | pdu | SCFA-other | 4,499 | 46,294 | Propanediol degradation S. enterica | PDU | 54%

No primary metabolite regions were found in these records:
  c00001_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_1)
  c00002_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_2)
  c00003_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_3)
  c00004_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_4)
  c00005_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_5)
  c00007_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_10)
  c00011_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_11)
  c00013_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_16)
  c00018_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_20)
  c00022_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_31)
  c00033_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_44)
  c00045_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_52)
  c00053_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_53)
  c00054_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_54)
  c00055_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_55)
  c00056_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_58)
  c00059_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_59)
  c00060_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_60)
  c00062_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_62)
  c00063_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_63)
  c00064_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_64)
  c00065_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_65)
  c00066_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_66)
  c00067_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_67)
  c00068_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_68)
  c00069_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_69)
  c00070_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_70)
  c00071_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_71)
  c00072_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_72)
  c00073_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_73)
  c00074_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_74)
  c00075_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_75)
  c00076_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_76)
  c00077_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_77)
  c00079_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_79)
  c00080_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_80)
  c00081_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_81)
  c00082_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_82)
  c00083_gnlPro.. (original name was: gnl|Prokka|LNNCGPNK_89)

Compact view
c00006_gnlPro.. - Region 1 - Oxidative_glycerol
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 35,148 - 72,557 nt. (total: 37,410 nt) Show pHMM detection rules used
Oxidative_glycerol: ((Fe-ADH or Fe-ADH_2) and Dak1 and Dak2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00012_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 25,145 - 49,383 nt. (total: 24,239 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00012_gnlPro.. - Region 2 - acetate2butyrate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 136,169 - 152,775 nt. (total: 16,607 nt) Show pHMM detection rules used
Region on contig edge.
acetate2butyrate: (not (POR or POR_N or PFOR_II) and minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00017_gnlPro.. - Region 1 - succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 21,605 - 46,577 nt. (total: 24,973 nt) Show pHMM detection rules used
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00021_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 29,546 - 46,875 nt. (total: 17,330 nt) Show pHMM detection rules used
Region on contig edge.
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00032_gnlPro.. - Region 1 - OD_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 8,133 - 31,393 nt. (total: 23,261 nt) Show pHMM detection rules used
Region on contig edge.
OD_AA_metabolism: (minimum(1, [PFOR_II, POR, POR_N]) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (Gly_radical_scatole or Gly_radical or Gly_430_pcre or Gly_8-9_TMA))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00061_gnlPro.. - Region 1 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 7,070 nt. (total: 7,070 nt) Show pHMM detection rules used
Region on contig edge.
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00078_gnlPro.. - Region 1 - pdu
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 4,499 - 46,294 nt. (total: 41,796 nt) Show pHMM detection rules used
pdu: (minimum(2, [Aldedh, BMC, Cob_adeno_trans, EutN_CcmL, Fe-ADH, Fe-ADH_2, PDU_like, PTAC, PduV-EutP]) and Dehydratase_MU and Dehydratase_SU and Dehydratase_LU)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.