LOCUS       c00012_gnlPro..        16607 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LNNCGPNK_12.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 18:04:17
            Original ID  :: gnl|Prokka|LNNCGPNK_12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 136168
            Orig. end    :: 152775
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16607
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[146168:152286]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..16118
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..16607
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16607
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="acetate2butyrate"
                     /region_number="2"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             2231..2701
                     /locus_tag="ctg12_116"
                     /transl_table=11
                     /translation="MLQKANQNLPINDVGIHRTQMQKEIILQKLKERGCRITRQRKMLL
                     DVILNEDCSSCKEIYYKASMKDSGIGTATVYRMINILEEIGALSRKNMYKIACGPECEV
                     KDACVIEFDDDTIIELSGKSWNQVVQLGLRACGYSSGHKIKSVTAKSCEFSR"
     CDS             7913..8179
                     /locus_tag="ctg12_117"
                     /transl_table=11
                     /translation="MAPAVREPMLGYHPCSTGFLTCARDPGGGQCQAGSLTGAVASERV
                     SEALKGLLRMVGNHPESAKAEGGLTATPTGGAGTKVGLSDPVA"
     CDS             10001..11182
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_118"
                     /sec_met_domain="Thiolase_N (E-value: 3.8e-103, bitscore:
                     337.3, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 7.7e-50, bitscore:
                     160.7, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKVVLAGACRTAIGTMGGGLSTVPAADLGSIVIKEALKRTNVP
                     ADQVDEVLMGCVIQAGLGQNVARQASINAGLPIEVPAVTINVVCGSGLNCVNLAATKIL
                     AGEADIVIAGGMENMSLAPFCLDKARFGYRMNNGVLKDCMVNDALTDAFNQYHMGITAE
                     NVAEQWHLTREELDEFSANSQQKATAAIEAGKFKDEIVPVEVKLKKKTVVVDTDEGPRP
                     GTTAESISKLRPAFKKDGIVTAANSSGINDGAACVVVMSEEKAKELGVTPMATWIAGAL
                     GGVDPSIMGVGPVASTKKVLAKTGMSIDDFDLIEANEAFAAQSLAVGRELGINPEKLNV
                     NGGAIALGHPVGASGCRILVTLLHEMQKRDAKKGLATLCIGGGMGCSTIVERD"
     CDS             11313..12098
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_119"
                     /sec_met_domain="EC1_2-faecali (E-value: 5.3e-91, bitscore:
                     297.3, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFIDYEVDGQVGIITINRPKALNALNSEVLKDLDATIDAVDLDA
                     IRCLIITGAGEKSFVAGADIGEMSTLTKAEGEAFGKAGNDVFRKIETLPIPVIAAVNGF
                     ALGGGCEISMSCDIRLCSENAVFGQPEVGLGITPGFGGTQRLARIVGPGKAKQLIYTAR
                     NIKAAEAYRIGLVNEVYPLEELMPQAKKMAKGIAKNAPIAVRACKKAINEGLEVGMDEA
                     IVIEEKLFGSCFETEDQKYGMAFFLDKNKEKVKEPFKNC"
     CDS             12167..13006
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_120"
                     /sec_met_domain="HCDH (E-value: 7.8e-38, bitscore: 122.1,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 6.7e-61, bitscore: 198.3,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGVIGAGTMGSGIAQAFAQTEGYEVYLCDINDEFAANGKKKIA
                     KGFEKRVARGKMDQAKADAILAKITTGTKDICTDADLVVEAALEVMEVKQQTFKELQDI
                     VPATCMFATNTSSLSITQIGAGLDRPVIGMHFFNPAPVMKLIEVIAGLNTPDEMVEKIK
                     AISVEIGKTPVQVEEAAGFVVNRILIPMINEAVGIYADGVASVEGIDTAMKLGANHPMG
                     PLALGDLVGLDICLAIMEVLYNETGDPKYRPHPLLRKMVRGGKLGQKTGIGFYDYSK"
     CDS             13107..14261
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_121"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.6e-51, bitscore:
                     167.5, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.9e-30, bitscore:
                     96.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.6e-40, bitscore:
                     131.3, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLSKKHEMARQLFKEFAENEVKPLAQEVDETEHFPEETVAKM
                     QKLGFMGIPVPKEYGGQGCDPLTYIMCVEELSKVCGTTGVIVSAHTSLCADPILTYGTE
                     EQKQKYLVPLAKGEKLGAFGLTEPGAGTDAQGVQTKAVLDGDEWVLNGSKCFITNGSYA
                     DYYIIIAITSVDTDARGRKKKKFSAFIVEKGTPGFTFGTKEKKMGIRGSATYELIFQDC
                     RIPKENLLGPMGKGFAIAMHTLDGGRIGIAAQALGIAEGALDATIAYVKERKQFGRAIA
                     AQQNTQFQLANMATQVEAAKLLVYKAAMAKATQRVYSVEAAKAKLFAAETAMDVTTKCV
                     QLLGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGNLLK"
     CDS             14276..15061
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 163.8;
                     E-value: 1.3e-50)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_122"
                     /sec_met_domain="ETF (E-value: 2.5e-50, bitscore: 163.8,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIVVCVKQVPDTKGGVKFKPDGTLDRAAMLTIMNPDDKAGLEAA
                     LRIKDETGAEVTVVTMGLPKAEEVLREAMAMGADKGILVTDRVLGGADTWATSTTIAGA
                     LRNIDYDLIITGRQAIDGDTAQVGPQIAEHLDLPLISYAQDIKVEGDSVIVQRQYDDRY
                     HVLKAKMPCVITALSELNEPRYMTPGGIFDAYDAEITTWGRKDLKDVDDSNLGLAGSPT
                     QIAKASDKVRKGKGVMMTAETAEEGVEYIMDKLLTKHVI"
     CDS             15078..16118
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 167.1;
                     E-value: 1.2e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_123"
                     /sec_met_domain="ETF (E-value: 2.5e-51, bitscore: 167.1,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 7.1e-38, bitscore:
                     121.6, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNRMNLEQYKGVFIYAQQVDNKIDAIALELLGKANDLAADLGTDV
                     TAVLIGSDVKGLVDELAEYGADKVIVVDDPELKEYRTEPYTHALASVINEYKPDILLVG
                     ATAIGRDLGPRVSARVATGLTADCTVLEIGEFKARGDKEPRQGQLLMTRPAFGGNTIAT
                     IACPNHRPQMATVRPGVMQKKEPVAGAKAEVIEYNPGFTPNDKYVEILDIVKSVTETVD
                     IQAAKILVSGGRGVGSAENFALLDDLAEALGGTVSCSRAVVDNGWKPKDLQVGQTGKTV
                     RPNVYFAIGISGAIQHVAGMEESDIIIAINKDPDAPIFDVADYGIVGDALKIVPKLTEA
                     IKAQVK"
ORIGIN
        1 acttatccac acagattatg gaacttggta ttccagtaat catggcaatc aacatgatgg
       61 acctcttaga gaaatctgga gagaagattg acattgcaaa acttggtaaa gaccttgggt
      121 gtgaagttgt tgagatttcc gcattaaaag gtactggaat caagaaggca gcagaaaagg
      181 cagttgcatt agcacagtct aagaagtctg cagaagttgt acatagcttt gataagaagg
      241 tagaagatgc aattgatgct gtaaaggtaa tgttgggttc tcaggttcca gaagaacaga
      301 aacgtttctt cgcaatcaag cttcttgaaa gagatgataa gattgtagaa cagttaaata
      361 cagttccaga tgtttctaat gagattaaag ctcttgaaga tgcattcgat gatgatacag
      421 aaagtatcat tactaacgaa agatatgtat acatttcttc cgtagtagca gatagctgca
      481 agaagaatgg agctaagaag cttacaacat ctgataagat tgaccgtatc gtaacaaacc
      541 gctggcttgc acttccaatt tttgcggttg ttatgttcat tgtttattat gtatccgtat
      601 ctacggtagg tgactgggca acgacctggg caaatgatgg agtatttggt gacggatggc
      661 atctctttgg tattaagtct cttttcatcc ctagtgttcc tagcattgta gaaggtgctt
      721 taaatgctgt tggatgtgca gactggttat ctggattaat tcttgatggt attgttgctg
      781 gtgttggtgc tgtacttggt ttcgtacctc agatgctcgt attatttatt ttccttgcat
      841 tcttagagtc ttgtggttac atggccagag ttgcattcat tatggataga attttccgta
      901 agtttggtct ttctggtaaa tctttcatcc caatgttaat tggtacagga tgtggtgttc
      961 ctggtgttat ggcatccaga acaattgaga atgaccgcga tcgaaaaatg acgatcatga
     1021 caactacatt cattccttgt ggagcaaaac ttccaattat cgcattaatt gcgggagcac
     1081 tttttaatgg agcatggtgg gttgcaccaa gcgcatattt tgttggtatt gcagcaatca
     1141 tttgctctgg tattatttta aagaaaacaa aaatgtttgc aggagagcct gcaccgtttg
     1201 ttatggaact tccagcttat catatgccaa ctgtttctaa cgtattaaga agtatgtggg
     1261 aaagagcatg gtctttcatc aaaaaagcag gaacaatcat tcttttatct acaatcatct
     1321 tatggttcct tatgaacttt ggatgggttg acggaaactt tggaatgctt gaggcagaac
     1381 agttaaatga cagtatttta gcaactatcg gtaatgtaat cgctccaatc tttgcacctc
     1441 ttggatgggg agactggaag atggcagttg cagccgttac tggattaatc gcaaaagaga
     1501 acgtagtagg tacattcggt attctcttcg gatttgcaga agttgcagaa gatggtagcg
     1561 aattctgggg acagcttgct aacagcttac cagcagtagc agcttactct ttcttagtgt
     1621 tcaacttact ttgtgcgcca tgtttcgcag ctatgggtgc tatcaagaga gagatgaaca
     1681 acattaaatg gttcttcttt gcaattggat accagtgctt acttgcttat gtagtaggtc
     1741 tttgcattta tcaggttggt acattaatca cagcaggtac attcggaatt ggtacagtag
     1801 tagcatttgt acttatcatc ggatttatct accttctgtt cagaccttac aaagaaagta
     1861 atacattaaa tgttaatgta aaaagcatag caaaggcaaa ataattaaaa agattatata
     1921 tctgttcaga attatgattt gtgattctga acagatgatc aatagtttac gataattgat
     1981 actttatata gaagggaagt gtatcagatg ggaacaataa ttgtgggact tatccttgtt
     2041 ttaatcgttt cccttattat tcgaagcatg gtaaaagata agaaaagcgg aaagtcaatt
     2101 caatgtggag gaagctgctc acattgtgcg ggacattgct ctgccccttg tgacactcct
     2161 tctaacagag attaagtata actattccga atagttgcga ttagattaga taaaagaaag
     2221 aagtgtggat atgctgcaaa aagctaatca gaatcttccg attaatgatg tgggaattca
     2281 cagaacacag atgcagaaag agataatatt gcaaaagtta aaagagcgtg gctgtcggat
     2341 taccagacag agaaagatgc ttttagatgt gattttgaat gaagactgct ccagttgcaa
     2401 agaaatttac tataaagcat ctatgaagga ttctggaatc ggaacagcta cagtataccg
     2461 catgattaat attctggaag aaatcggtgc attaagtcga aagaacatgt ataagattgc
     2521 gtgtggaccg gaatgtgaag tcaaagacgc ctgcgtgatt gaattcgatg atgatacgat
     2581 tattgaactt tccggcaaaa gctggaatca ggtagtgcag ttagggttaa gagcctgtgg
     2641 ttactccagc ggtcataaga ttaagagtgt aactgcgaag tcctgtgaat tttcaagata
     2701 aaaataaaaa atatatgcca ttatagaata accctggaag acttaaatct tctgggggtt
     2761 atttattttg ataaaaaaat aacaatttaa taagccagat atgtggcgtg aatgataaaa
     2821 atacagaaaa aatacaatat ctagtgcttg ttgataaaat aaaaaaatct tcaaaaaatg
     2881 cttgacgcaa ctctactgtt atgataatat aatatgcgtt gcacatgaga aacacatttt
     2941 tgaaagaaaa atgataaaaa tcttaaaaga aaacgaaaaa acttcttgac agattgaaaa
     3001 tcgtgtgata acatataaaa gttcacattt gacagagaga acggacttct taaaaagacg
     3061 aaaaagttct tgaaaaaagt tcttgacaaa aacttgagag tgtgataata taattaagcg
     3121 ttttcgaaag aaaacataaa accttgataa ctgaataaca aaacaacctt gaacgttaat
     3181 tcaaatttca ttcgggtttt cctgagagtg atgtctgcag gaaagtccat ggaacagaac
     3241 gaaagttcaa aacctaaata aacagtaatg acaggaaaag aaccagtggt tctggacctt
     3301 gatctgacat cttgaacatt ttatttgaga gtttgatcct ggctcaggat gaacgctggc
     3361 ggcgtgccta acacatgcaa gtcgaacgaa gcaccttttg agattcttcg gatgatcgat
     3421 tggtgactga gtggcggacg ggtgagtaac gcgtgggtaa cctgccctgt acagggggat
     3481 aacagctgga aacggctgct aataccgcat aagcgcacga ggagacatct ccttgtgtga
     3541 aaaactccgg tggtacagga tgggcccgcg tctgattagc tggttggcag ggtaacggcc
     3601 taccaaggca acgatcagta gccggtctga gaggatgaac ggccacattg gaactgagac
     3661 acggtccaaa ctcctacggg aggcagcagt ggggaatatt gcacaatggg ggaaaccctg
     3721 atgcagcaac gccgcgtgag tgaagaagta tttcggtatg taaagctcta tcagcaggga
     3781 agataatgac ggtacctgac taagaagctc cggctaaata cgtgccagca gccgcggtaa
     3841 tacgtatgga gcaagcgtta tccggattta ctgggtgtaa agggtgcgta ggtggcagtg
     3901 caagtcagat gtgaaaggcc ggggctcaac cccggagctg catttgaaac tgctcggcta
     3961 gagtacagga gaggcaggcg gaattcctag tgtagcggtg aaatgcgtag atattaggag
     4021 gaacaccagt ggcgaaggcg gcctgctgga ctgttactga cactgaggca cgaaagcgtg
     4081 gggagcaaac aggattagat accctggtag tccacgccgt aaacgatgaa tactaggtgt
     4141 cggggccgta taggctccgg tgtcgccgct aacgcagtaa gtattccacc tggggagtac
     4201 gttcgcaaga atgaaactca aaggaattga cggggacccg cacaagcggt ggagcatgtg
     4261 gtttaattcg aagcaacgcg aagaacctta ccaggtcttg acatccttct gaccgcacct
     4321 taatcggtgc tttccttcgg gacagaagag acaggtggtg catggttgtc gtcagctcgt
     4381 gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc cctatcttca gtagccagca
     4441 ggtaaggctg ggcactctgg agagactgcc agggataacc tggaggaagg tggggacgac
     4501 gtcaaatcat catgcccctt atgatctggg cgacacacgt gctacaatgg cggtcacaga
     4561 gtgaggcgaa cccgcgaggg ggagcaaacc acaaaaaggc cgtcccagtt cggactgtag
     4621 tctgcaaccc gactacacga agctggaatc gctagtaatc gcgaatcaga atgtcgcggt
     4681 gaatacgttc ccgggtcttg tacacaccgc ccgtcacacc atgggagtcg gaaatgcccg
     4741 aagccagtga cccaaccttt tggagggagc tgtcgaaggt ggagccggta actggggtga
     4801 agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggaaga
     4861 caagtagaga gttgttttgt tattcagtta tcaagcaaaa acttgataag atattttcgg
     4921 tggcgatgcg ctcaggggac acacccgttc ccatcccgaa cacgatggtt aagacctgag
     4981 cggccgatgg tactatgctg gagacggcat gggagagcag gtggctgccg gattcccttg
     5041 ggggattagc tcagttggga gagcgcctga cttgcaagca ggaggtcacg agttcgaatc
     5101 tcgtattctc cactgagggc tcatagctca gctggttaga gcgcacgcct gataagcgtg
     5161 aggtcggtgg ttcgagtcca cttgagccca tagggtgaaa gagaaagaaa gtcttcaatc
     5221 tgaaggaaag gttcacttaa gcccatagat aaccatgatt gaatggttat cacaattcgn
     5281 nnnnnnnnng agacggcatg ggagagcagg tggctgccgg attcccttgg gggattagct
     5341 cagttgggag agcgcctgcc ttgcaagcag gaggtcacga gttcgaatct cgtattctcc
     5401 acttggtatc ttgataaagt tgggataccg catgataatg taccttgaaa actgcacaca
     5461 gaaagttttc tataaaacga gcaatgcaga ctgcgaatga tgcagatggc ggaaatatat
     5521 ttccagacat tactgcagaa gaagcaggct atagtgcgac agcacgaatc gagaggaagt
     5581 gtgagcggac tcgagatggg gcattgcgaa gaaacgttag aaagcgacat cagatttcta
     5641 tgataagaaa gaattgagac taaatcaatt ctcccaatag caagtcgaaa gacgaaaaca
     5701 tgagttttaa ctcatacgcc gaatgttctc tacgctagga ggaacaggag gcagccattt
     5761 cttaggaaat ggacatacaa aggtcaagcg aagaagggcg cagggcggat gccttggcac
     5821 tgagagccga tgaaagacgt gataagctgc gataagcttc ggggaggagc aaatatcctt
     5881 tgatccggag atctctgaat ggggaaaccc ggctgtatgg actacagtca tccataagtg
     5941 aatccatagc ttatggaagg gaacccgggg aactgaaaca tctaagtacc cggaggaaga
     6001 gaaagaaaca ttcgattccg taagtagcgg cgagcgaacg cggaagagcc caaaccgtga
     6061 tgcgtgcatc gcggggttcg gactgcataa gggattcagt aacggcagga gaacggcttt
     6121 ggaacagccg gccagagagg gtgagagccc cgtatccgaa gccagagctg acccggcagg
     6181 atccagagta ccacgggaca cgggaaaccc tgtgggaacg agcggagacc actccgtaag
     6241 gctaaatact actcagtgac cgatagcgta tagtactgtg aaggaaaggt gaaaagaacc
     6301 ccgggagggg agtgaaagag aacctgaaac cctgtgtcta caagctgtgg aagtgcttct
     6361 tatgcacgac cgcgtacttt ttgtagaacg gtccggcgag ctgcgggtac tggcaaggtt
     6421 aagcacttca ggtgcggagc cgtagggaaa ccaagtctta agagggcgtt ttagtcagta
     6481 cgtgcaggcc cgaaaccggg tgacctatcc atgtccaggt tgaagccgcc gtaaaaggcg
     6541 atggaggacc gaacccacat ccgttgaaaa gggtggggat gaggtgtgga tagcggagaa
     6601 attccaatcg aacccggaga tagctggttc tcctcgaaat agctttaggg ctagcctcat
     6661 acaagtctgc cggaggtaga gcactgaatt tccgcggggg cgtcaaagcc taccaaagaa
     6721 tatcaaactc cgaatgccgg acagatggtg tatgggagtc agactgtacg agataagttg
     6781 gacagtcaaa agggaaagag cccagaccgc cggctaaggt cccaaagtgg gtgttaagtg
     6841 gaaaaggatg tgggatctct aagacaacca ggatgttggc tcagaagcag ccattcatta
     6901 aaagagtgcg taacagctca ctggtcgaga ggtcctgcgc cgaaaatgtc cggggctgaa
     6961 acaccacacc gaagccgcgg aacccgtaag ggttggtaga ggagcattct taggggagcg
     7021 aagcattacc ggaaggggat gtggaccgct aagaagagag aatgccggaa tgagtagcga
     7081 gagcaaggtg ggaatccttg cggccgaata tccaaggttt ccagagtaaa gctgatctgc
     7141 tctgggtaag tcggggccta aggagaggca gagatgcgta tccgatggac agcaggttta
     7201 agattcctgc accccttgtt atcagaactg cggggacacg ggaagggaag cagagccggg
     7261 aatggaaagc ccggtgcaag cgaaggagtc gcagggttgg aaaatccgcc ctgcatgaga
     7321 cgaaggcgtg atgcggagcg aaatgaagta gtgaagctgc ggccccttcc tgtcgagaaa
     7381 agccgctatc gtgtagcaag ggcccgtacc gtaaaccgac acaggtggat gaggagagga
     7441 tcctaaggcc ggcgggagaa gtgttgttaa ggaactcggc aaaatgactc cgtaacttcg
     7501 ggagaaggag tgctgcgcaa gcagccgcag agaaatggcc caagcaactg tttagcaaaa
     7561 acacaggtct atgcgaaacc gaaaggtgag gtatatgggc tgacgcctgc ccggtgctgg
     7621 aaggttaagg ggagagctta gcgcgagcga aggtttgaac ttaagcccca gtaaacggcg
     7681 gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt ccgacccgca
     7741 cgaaaggcgt aatgatttgg gcactgtctc aacaacacac ccggtgaaat tgaaatacca
     7801 gtgaagatgc tggttacccg cgccaggacg gaaagacccc atggagcttt actccagcct
     7861 gatactggga ttcggtattg catgtacagg ataggtggga ggctgagaac ttatggcgcc
     7921 agccgtgagg gagccgatgt tgggatacca cccctgcagt actgggtttc taacctgcgc
     7981 ccgtgacccg ggcgggggac aatgtcaggc ggggagtttg actggggcgg tcgcctccga
     8041 aagggtatcg gaggcgctca aaggtctcct caggatggtt ggaaaccatc cagagagtgc
     8101 aaaggcagaa ggaggcttga ctgcgacacc gacgggtgga gcaggtacga aagtaggact
     8161 tagtgatccg gtggcataaa gtgggattgc catcgctcaa cggataaaag ctaccctggg
     8221 gataacaggc ttatcactcc caagagttca catcgacgga gtggtttggc acctcgatgt
     8281 cggctcatcg catcctggag ctggagcagg ttccaagggt tgggctgttc gcccattaaa
     8341 gcggtacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc cggcgcgggc
     8401 gcaggatatc tgagaggagc tgtccttagt acgagaggac cgggatggac cgtccgctgg
     8461 tggaccggtt gtcatgccaa tggcacggcc gggtagccaa gacgggaagg gataaacgct
     8521 gaaggcatct aagcgtgaag cccccctcaa gatgagatat ccatactcga aagagtgaga
     8581 gaccccttag agacgatgag gtagataggg cagagatgga agcacagcga tgtgtggagt
     8641 tgactgttac taatcggtcg atagcttgac cttaaaagta cttgcaaagt tcaaagagat
     8701 atgatataat gtgtgtggtt ttcagggtat gacacctgac aatattcctc gatagctcag
     8761 tcggtagagc acgcggctgt taaccgcgct gtcgtaggtt caagtcctac tcggggagtc
     8821 tggctccttn nnnnnnnnng tcgtaggttc aagtcctact cggggagtct ggctccttgg
     8881 tcaagtggtt aagacaccgc cctttcacgg cggtaacatg ggttcaaatc ccgtaggagt
     8941 cacttgtggc gtcgtagcca agtggtaagg cagaggtctg caacaccttc atcaccagtt
     9001 caaatctggt cgacgcctct taaaagagac taagtgatta gtctcttttt agcatttctt
     9061 tttaatttaa tatcgcgggg tagagcagtc tggtagctcg tcgggctcat aacccggagg
     9121 tcgttggttc aaatccttcc cccgcaattt gaggaacatc ggtacattgg tatcggtgtt
     9181 tttttatttg tttaaactga cgcaatagta aaacccgcta taagtctatc tgtgacttta
     9241 gtcgcggcgt gttgaatgtt cgcttagacg ctcgtatcca acacttgctc cgaggccaca
     9301 gatagactta tagcgagctt tactattgct ggctttgaag gaaacaaagt aaaaattctt
     9361 agatgtgcaa cgattcgatg ttggggagag tgtgtgaatt taaaatatag attttttggt
     9421 attgattttg ttaatataat tacaatgata aaaacaaatt gcaatacaaa atatacataa
     9481 tttcatctac agctatccgg gcaattttca aatccctcca tatagacatt ctaaactaaa
     9541 tccttccaac agatagaaaa gccagagata ctttatgtac catatgcttt atttcactgt
     9601 gcaaaatgcc ataaaactca ctccaaagcc acatctggca ggtaaagtat ctctggtttt
     9661 tcgtctatta gccaactcag aatgtctatt tcttcacata tttaggcagt tttttgtatt
     9721 ttgtttcctt ttttcacaaa atcagaaaat taatcaatag agaatgtcca tagatataag
     9781 aagaaataaa ggtaaaatta attaaaacaa cgatggattt tgtattcaaa agtgacgaaa
     9841 ctgtgaatct ttcataaatg aaaatattaa ttaaaaattt ttttataatc ttgttgcaaa
     9901 gcaaagaaga ttgtgataag attaacacat atcgtactag aaatgctcta gcaaagcaac
     9961 tatcaaataa tattgataac ttaaatggag gaatgaaact atggcaaaga aagttgtatt
    10021 agcaggtgct tgtcgtaccg caatcggaac aatgggtggt ggattaagca cagtaccagc
    10081 tgcagattta ggaagcatcg taattaaaga agcgttaaag agaactaacg tacctgctga
    10141 tcaggtagac gaagtattaa tgggatgtgt tatccaggct ggtcttggac agaacgttgc
    10201 tcgtcaggct tctattaatg caggcttacc aatcgaagta cctgctgtaa caattaacgt
    10261 agtttgtggt tccggtctta actgtgttaa ccttgctgct acaaagattt tagcaggtga
    10321 ggctgatatc gttatcgctg gtggtatgga aaacatgtca ttagctccat tctgcttaga
    10381 caaagctcgt tttggataca gaatgaacaa tggcgtatta aaagactgta tggttaacga
    10441 tgcattaaca gatgctttca atcagtacca tatgggtatt acagctgaaa acgttgcaga
    10501 acagtggcat ttaacaagag aagagttaga tgagttctcc gctaattcac agcagaaagc
    10561 tacagcagct atcgaagctg gtaagttcaa agatgagatt gttcctgtag aagttaaact
    10621 taaaaagaaa acagttgttg tagatacaga tgagggacca cgtcctggaa caacagcaga
    10681 aagtatttct aaattacgtc ctgctttcaa gaaagatggt atcgtaacag ctgccaactc
    10741 ttcaggtatt aacgatggtg ctgcttgtgt tgttgttatg agcgaagaaa aagctaaaga
    10801 attaggtgta actccaatgg ctacatggat agcaggagca ttaggcggag ttgatccttc
    10861 tatcatgggt gttggaccag ttgcttctac taagaaagtt cttgcaaaaa caggcatgag
    10921 cattgatgac tttgacttaa tcgaagctaa cgaagctttc gcagctcagt cattagcagt
    10981 aggaagagaa ttaggaatca acccagagaa gttaaatgtt aatggtggag ctattgctct
    11041 tggacatcca gtaggagcat caggatgccg tatcctcgtt acattattac atgagatgca
    11101 gaaacgtgat gctaagaaag gtcttgctac actgtgtatc ggtggtggta tgggctgctc
    11161 aacaatcgtt gaaagagact aatcacgtat agaatgatta catatatccg ggttcggttt
    11221 tcgaatccgg ttatatcaat tacatagttt gtaactattt aattatctag attgaatagt
    11281 tagctaatgt aatctgaaag gagatacata caatgggatt tatcgattat gaagtagatg
    11341 gccaggttgg tattatcacc atcaatcgtc caaaggcttt aaatgcttta aacagtgaag
    11401 tattaaaaga tttagatgca actattgatg cagtagattt agacgcaatc agatgtctta
    11461 tcattactgg tgctggagag aaatctttcg tagcaggtgc tgatatcgga gagatgagta
    11521 cacttacaaa agcagaaggc gaagctttcg gtaaagctgg taatgatgta ttcagaaaga
    11581 ttgaaacact tccaatccct gttatcgcag cagtcaacgg attcgcttta ggcggtggct
    11641 gtgagatttc tatgagctgt gacatcagac tttgctctga gaatgcagtg tttggacagc
    11701 cagaagttgg tcttggaatt acacctggtt ttggtggaac acagagactt gctcgtatcg
    11761 taggacctgg aaaagcaaaa cagttaatct atactgctcg caatattaaa gcagcagaag
    11821 cttacagaat tggtctggtt aacgaagttt atccacttga agagttaatg cctcaggcta
    11881 agaagatggc aaagggtatt gcaaagaacg cacctatcgc agttcgtgca tgtaagaaag
    11941 ctatcaacga aggtttagaa gtaggaatgg atgaagctat cgtaatcgaa gagaagttat
    12001 ttggcagctg cttcgagaca gaagaccaga aatacggaat ggcattcttc cttgacaaaa
    12061 acaaagaaaa agtaaaagag ccatttaaaa actgctaatt aatcaattat acatattgta
    12121 ttattaatta tcggaataca ttacatttta taggaggttt cagacaatga aagttggagt
    12181 tattggcgca ggtacaatgg gatcaggtat tgctcaggca ttcgcacaga cagaaggata
    12241 cgaagtatac ttatgtgata ttaacgatga atttgctgca aacggtaaaa agaaaatcgc
    12301 taaaggattt gaaaagagag tagcaagagg aaaaatggat caggctaaag ctgatgcaat
    12361 ccttgctaaa atcactacag gtacaaaaga tatctgtaca gatgctgatt tagtagtaga
    12421 agcagctctt gaagttatgg aagttaaaca gcagacattt aaggaattac aggatatcgt
    12481 tcctgcaaca tgtatgtttg caacaaatac atcttcttta tctattacac agattggtgc
    12541 aggacttgac agaccagtta tcggaatgca tttcttcaac ccagctccag ttatgaaatt
    12601 aattgaagtt atcgctggtc ttaatacacc agatgaaatg gttgaaaaga ttaaagctat
    12661 ctccgtagaa atcggcaaaa cacctgtaca ggtagaagaa gctgcaggat tcgtagttaa
    12721 cagaatctta atcccaatga ttaacgaagc agttggcatt tatgctgatg gtgttgcttc
    12781 tgttgaaggt atcgacacag ctatgaagtt aggtgctaac catccaatgg gacctctcgc
    12841 tttaggagat ttagttggtc ttgatatctg ccttgcaatc atggaagtat tatataatga
    12901 aacaggagat cctaagtatc gtccacatcc attattaaga aagatggttc gtggtggaaa
    12961 attaggtcag aagactggta ttggattcta cgattacagc aaataattaa aaaagtgaat
    13021 acggccgtgg ggactatgct ctgcgtctcc acggctttta aggtggttct ccaccccaat
    13081 aaccaattta ttatggagga atgaaaatgg atttcacatt aagcaaaaag catgaaatgg
    13141 ctagacagct ctttaaagag ttcgctgaaa acgaagttaa acctcttgct caggaggttg
    13201 acgagacaga acattttcca gaagaaaccg ttgcaaaaat gcaaaaatta ggtttcatgg
    13261 gaattcctgt gccaaaagaa tatggcggac agggctgtga tcctttaaca tacattatgt
    13321 gtgttgaaga gttatctaaa gtttgtggta caacaggtgt tattgtatcc gcacatacat
    13381 cattgtgtgc agatccaatt cttacttacg gtactgaaga acagaaacag aaatatcttg
    13441 ttccacttgc aaagggtgaa aagttaggtg ctttcggtct tacagagcca ggtgctggta
    13501 ctgacgctca gggtgttcag acaaaggctg ttttagatgg tgacgaatgg gtattaaacg
    13561 gatctaaatg tttcatcact aacggttctt atgctgatta ctatattatc atcgctatca
    13621 caagtgttga tacagatgca agaggaagaa agaaaaagaa attctccgca tttatcgtag
    13681 aaaaaggaac tccaggattt acatttggta caaaagaaaa gaaaatgggt atccgtggtt
    13741 cagctacata tgaattgatt ttccaggatt gtcgtattcc taaagaaaat cttcttggac
    13801 ctatgggcaa aggtttcgca atcgctatgc acacattaga tggtggacgt atcggtattg
    13861 cagctcaggc tcttggtatc gcagaaggtg ctttagatgc tacaattgct tatgttaaag
    13921 aaagaaaaca gtttggcaga gcaattgctg cacagcagaa tacacagttc cagcttgcta
    13981 atatggctac acaggtagaa gctgctaagt tacttgttta taaagcagca atggcaaaag
    14041 caacacagag agtatactcc gtagaagcag caaaagctaa attatttgca gcagaaacag
    14101 ctatggatgt aacaactaag tgtgttcagt tacttggtgg ttatggttac atcagagagt
    14161 acgacgtaga acgtatgatg cgtgacgcta agatcacaga aatctacgaa ggaacatcag
    14221 aagttcagcg tatggttatt tctggtaact tattgaaata aggagggaaa atactgtgaa
    14281 aatcgtagta tgtgttaaac aggtacctga tacaaaaggt ggagttaagt ttaaaccaga
    14341 cggaactctt gatagagcag ctatgcttac tatcatgaat ccagatgata aggcaggtct
    14401 tgaagctgcc cttagaataa aagatgaaac aggcgcagaa gtaacagtag ttactatggg
    14461 tcttccaaaa gcagaagaag ttctgcgtga agctatggca atgggtgctg acaagggtat
    14521 ccttgtaaca gaccgtgttt taggtggagc tgatacatgg gcaacatcta caacaatcgc
    14581 tggagcactt agaaatattg attatgattt aatcatcaca ggtcgtcagg ctatcgatgg
    14641 tgatactgct caggtaggac ctcagattgc tgaacactta gatcttcctt taatttccta
    14701 tgctcaggat atcaaagttg aaggtgacag tgtaatcgtt cagagacagt atgacgacag
    14761 atatcatgtt ttaaaagcta aaatgccatg tgttatcaca gcactttccg aattaaatga
    14821 gccacgttat atgactccag gcggaatctt tgatgcatat gatgcagaaa ttactacatg
    14881 gggaagaaaa gaccttaaag atgttgatga cagcaactta ggtcttgcag gttctccaac
    14941 tcagatcgca aaagcttctg ataaggtacg taaaggtaaa ggtgtcatga tgacagctga
    15001 aacagcagaa gaaggcgttg agtacatcat ggacaaactg ttaacaaagc atgttatcta
    15061 attgtaaagg aaatgtggtg aatagaatga atttagaaca atataaaggt gtatttatct
    15121 atgctcagca ggttgacaat aagattgatg ccattgcttt agaattactt ggaaaagcaa
    15181 atgaccttgc tgcagattta ggaacagacg taacagcagt tttaatcggt tctgacgtaa
    15241 aaggcttagt tgatgaactt gctgaatacg gcgcagataa agttatcgta gttgatgacc
    15301 ctgaattaaa agaatacaga acagagccat atacacatgc actggcatct gttatcaacg
    15361 aatacaaacc ggacattctt ctggttggag caacagcaat cggtcgtgac ttaggacctc
    15421 gtgtttctgc aagagttgca acaggtctta cagcagactg tactgttctt gaaattggtg
    15481 aattcaaagc tcgtggagat aaagaacctc gtcagggtca gttattaatg actcgtcctg
    15541 cattcggtgg taacacaatc gctacaatcg cttgtcctaa ccatcgtcca cagatggcta
    15601 cagttcgtcc tggtgttatg cagaagaaag agcctgttgc aggtgcaaag gcagaagtta
    15661 ttgagtacaa tccaggattt actccaaatg acaaatatgt tgagattctt gacattgtaa
    15721 aatctgttac agaaacagtt gatatccagg ctgctaagat tcttgtatct ggcggacgtg
    15781 gagttggctc tgctgagaac tttgcattat tagacgattt agcagaggca cttggcggaa
    15841 cagtttcctg ttctcgtgca gttgttgata atggttggaa accaaaagat ttgcaggttg
    15901 gccagactgg taagacagtt cgtcctaatg tttattttgc aatcggtatt tccggagcta
    15961 tccagcacgt agctggtatg gaagaatctg atatcatcat cgctattaat aaagatccag
    16021 atgcacctat ctttgatgta gctgattacg gtattgttgg cgatgcatta aagattgttc
    16081 ctaagttaac agaggcaatc aaagctcagg ttaaataatt tcaaatcata tcagactcat
    16141 tagattatgt gagttactga ttgaggattg aaacttagat tttttgtgga agtctagtat
    16201 atgcattctc agatgttttg tgtattgacg attcattatt aaaagaagca tataggagat
    16261 ttgtgctgaa ctctataaaa tgtatttatg cagggaatct ttttgaagat tccctgttaa
    16321 agtgagatag taggactaca gtttataact gtggtctttt ttactttcat tcagttggca
    16381 tagcccgcta cgccgtcttc attcaggaaa aattccccac aaattgtaac gcacatcttg
    16441 caaaagcatt tttcaaacac gctctagtat agtatccatt cagtgtttat gaataattat
    16501 ttgatagttc acaataaaag atgcacgaag taaattagaa aaactatatc caataatatt
    16561 ttagaaatta gatagatgct atactagagc gtgtttgaaa aatcatt
//
