Select genomic region:
Overview
1.1
5.1
34.1
45.1
47.1
47.2

### Identified primary metabolite regions

c00001_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_1)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | TPP_AA_metabolism,Others_HGD_unassigned | Putative | 1 | 24,559 |

c00005_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_5)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 5.1 | porA | SCFA | 1 | 17,010 |

c00034_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_34)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 34.1 | succinate2propionate,Rnf_complex | E-MGC | 151,014 | 189,348 | Rnf complex C. sporogenes | RNF | 100%

c00045_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_45)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 45.1 | Arginine2putrescine,Putrescine2spermidine | Aliphatic_amine | 174,339 | 205,462 | Putrescine2spermidine E. rectale | SPRM | 100%

c00047_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_56)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 47.1 | acetate2butyrate | SCFA | 9,942 | 35,237 | Acetate to butyrate C. sporogenes | BUT | 83%
Region 47.2 | Pyruvate2acetate-formate | SCFA | 131,847 | 154,981 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | TPP_AA_metabolism,Others_HGD_unassigned | Putative | 1 | 24,559 |
Region 5.1 | porA | SCFA | 1 | 17,010 |
Region 34.1 | succinate2propionate,Rnf_complex | E-MGC | 151,014 | 189,348 | Rnf complex C. sporogenes | RNF | 100%
Region 45.1 | Arginine2putrescine,Putrescine2spermidine | Aliphatic_amine | 174,339 | 205,462 | Putrescine2spermidine E. rectale | SPRM | 100%
Region 47.1 | acetate2butyrate | SCFA | 9,942 | 35,237 | Acetate to butyrate C. sporogenes | BUT | 83%
Region 47.2 | Pyruvate2acetate-formate | SCFA | 131,847 | 154,981 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%

No primary metabolite regions were found in these records:
  c00002_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_2)
  c00003_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_3)
  c00004_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_4)
  c00006_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_6)
  c00007_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_10)
  c00011_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_11)
  c00012_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_12)
  c00013_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_16)
  c00017_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_17)
  c00018_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_32)
  c00033_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_33)
  c00035_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_44)
  c00046_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_46)
  c00048_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_59)
  c00049_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_60)
  c00050_gnlPro.. (original name was: gnl|Prokka|HCIBMOPF_61)

Compact view
c00001_gnlPro.. - Region 1 - Others_HGD_unassigned,TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 24,559 nt. (total: 24,559 nt) Show pHMM detection rules used
Region on contig edge.
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00005_gnlPro.. - Region 1 - porA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 17,010 nt. (total: 17,010 nt) Show pHMM detection rules used
Region on contig edge.
porA: (Fer4_7 and TPP_enzyme_C and POR and POR_N and PFOR_II and not (EKR or Fer4_16))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00034_gnlPro.. - Region 1 - Rnf_complex,succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 151,014 - 189,348 nt. (total: 38,335 nt) Show pHMM detection rules used
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00045_gnlPro.. - Region 1 - Arginine2putrescine,Putrescine2spermidine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 174,339 - 205,462 nt. (total: 31,124 nt) Show pHMM detection rules used
Arginine2putrescine: (minimum(3, [AdoMet_dc, Amidinotransf, Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))
Putrescine2spermidine: (minimum(2, [AdoMet_dc, Spermine_synt_N, Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00047_gnlPro.. - Region 1 - acetate2butyrate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 9,942 - 35,237 nt. (total: 25,296 nt) Show pHMM detection rules used
acetate2butyrate: (not (POR or POR_N or PFOR_II) and minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00047_gnlPro.. - Region 2 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 131,847 - 154,981 nt. (total: 23,135 nt) Show pHMM detection rules used
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.