LOCUS       c00004_gnlPro..        16531 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HBELKINO_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 17:12:18
            Original ID  :: gnl|Prokka|HBELKINO_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16531
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16531
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2973:6531](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2974..6531
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16531
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16531
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(401..1555)
                     /locus_tag="ctg4_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1762..2940
                     /locus_tag="ctg4_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLWKDHKVHKGD
                     KNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGFLY"
     CDS             2974..6531
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="PFOR_II (E-value: 5.1e-18, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.3e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 8e-31, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-11, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.6e-11, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.7e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00026, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-24, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6656..6844
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MIGFVIWIVGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(6855..7715)
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MNKIKMIVAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNAETIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPKKD"
     CDS             complement(7743..8573)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-28, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8570..9796)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10270..11556
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVTIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLFIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSTGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11519..11851)
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWGEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(11879..14632)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63.8; E-value: 5.9e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.1e-19, bitscore:
                     63.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPHFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNTKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGTISVESDEKQGTIFTVELPVQSCEAV
                     TAEPDTTLVSPDSRTTDVLLAEEEELEKGYDSSKSSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(14965..16191)
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 attcatttta gttgatactt atagtagtca accaaatcca gggtaagaca aaccgcatgt
       61 tccaatcaca ttgaacgcat cagctacttc aatagtactg ctctctctga aaacattaaa
      121 tcatatatca gtcaataata cataaattat cagtccttaa tacttgattt ctcaattatt
      181 aatatctgag aaatcaaacg ttaacagttg agatatcaga tattaacatc ctgtaaatca
      241 aagaataaca cagtaaaaac ggtatttatc aggacgatgc agagtgagag caagtccttg
      301 ctctcactct gctaccactg gatctctaac agctaaaaca tcgatgaata aagggataca
      361 gacgaactgt tagagcatga gagcaaaagc actatctttt tcactggggg agagtaagca
      421 aaagaaacgc acgataccgg ctttgaggcg tcaccggtac taacggcaaa tatccggcac
      481 acacccgatt attctctacg gacaaaggga acgaagccga catctgccga tgttcctcca
      541 aagcctgacc ggctaaagga taataatcaa tccgaaaaac tccttccgca tccgcagcca
      601 aataacgatc cgtcaagagc catgccacca cccccatatt cattcgcaga ttaatttcga
      661 cacaaggatg aatccggtaa acaggcgctt catccggaaa atgacaaatc atcatatcca
      721 ctcccaagta tccatgataa aagccaccga acaaagctga caattcttct tccaaacgag
      781 tccgcagcct gataaattct tcttgtggca cataagccga tagtttctgc agaatcttct
      841 cgtcagacag caagtcattc cctgcataca tcccactccc acccgtgtgg aagaccgaat
      901 atccggcaaa aacaaccctt cctctcccgt cagcataaaa ctccatagcg aaatcttcca
      961 ccttattata tataggttcg cctaccaccc caccctgaga agcagcgaca cgggcacacc
     1021 aaccggaaat aaaagtagta aatatgcctt tacaccaatt caatcctttc ccgcttccgg
     1081 aaagcggagc ttttaacaag cacgcttccc gcccttcgac gaacgcactg cactccgcca
     1141 aagtactcaa ataaaaagat tctccacaga agtattcatt caaccgcaac ccaggcaaca
     1201 actttaccgc ctgcagacga tgcgaatgct ctctcagaat attcatataa tccgcagaag
     1261 gcagctccgt ctgacctgcc cccaatgtca tcaaacgctt ccgcaaagca gggtcccacc
     1321 cccacggaga gaacttccgg tctttaccgt cagccacttc cggttccgtc aacaaggcca
     1381 catccatgcc caaaagttca ctctttgttt tcaggaagtc cgcattataa gcagacggtg
     1441 caagcaccgc acttcccgct tcggcatacc acataggaag caacgccagg tcactcgcca
     1501 tctgtcgggc ggaagccggc gccatatagt tcgtctcacc gcttgccaac gccatatcat
     1561 gctccggatt gaatatataa acaggtcttt tcgtcatgtc aaagatggat tcaacacatt
     1621 attctgcaaa tatatacagg aaataatcag gaacttacac aataaagaga aacttataaa
     1681 ttaaagcaca tttttgctat ctctactttg caaatcctaa aaaaagcact atatttgcca
     1741 gccgaaaaac aaagaaacga aatggaatca ttctatcgca cacacgccta cctcgttgag
     1801 cacaccaatg cccccgttcg ccgcgatctt atggacgaga tcgactggag tgaccgtctg
     1861 attggtatca aagggacacg tggcgtagga aaaaccactt tcctcctgca gtacgccaaa
     1921 gagaaattcg gcaccgaccg ttcctgtctg ttcatcaata tgaacaactt ttatttctcc
     1981 ggtcacagcc ttgttgactt cgccaacgag tttcagaaac gtggcggaaa agtactgctg
     2041 atcgaccagg tgttcaaaca tcccgaatgg agcaaagagc tacgaatgtg ctatgaccgt
     2101 ttccccagcc tgaagattgt cttcaccggt tcttccgtca tgcgactcaa agaggaaaac
     2161 ctcgaattgc gtgacattgc gaaaagttat aacctgcgcg gattctcttt ccgtgaattt
     2221 ctgaacctgc agacaggaat gaaattccgg gcatacagcc tcgaagaaat cctcagtaca
     2281 catgaacaga tagccaaagg agtactttcc aaagtacgac cgctggatta ttttcaggat
     2341 tacctgcatc atggtttcta ccctttcttc cttgaaaaac gtaatttctc ggagaatctg
     2401 ctgaaaacaa tgaacatgat ggtagaagtg gatatcttgc tgatcaaaca aattgagctg
     2461 aaatatcttt caaagataaa aaaattacta tatttgttgg ctgtggacgg accgaaagct
     2521 ccgaacgtga gccaactggc aagtgacgta cagacatccc gcgctacggt aatgaactat
     2581 atcaagtatc tggcagacgc gcgtctgatt aatctggttt acccgaaagg agaagaattc
     2641 ccaaagaaac cgtcaaagat tatgatgcac aactctaacc tgatgtactc catttatcca
     2701 gtgaaagtgg aagaacagga tgtactcgac acgttcttcg ttaacacttt atggaaagac
     2761 cataaggtac ataaaggaga taaaaacgtc tctttcatgg tagacgaagt gatgccgttc
     2821 aaaatttgtg cggaaggtac aaaaataaag aataacccgg acgtgacgta tgcgttgcaa
     2881 aaggctgaga taggccgcgg caaccaaata cctctctgga tgttcggatt cttatactaa
     2941 aaagatttat ttacttaaat atttaattta gttatgacta aacagaagaa attcatcaca
     3001 tgtgatggta accaagctgc agcacatatc tcgtatatgt tctctgaagt agcagctatc
     3061 taccccatca ctccttcttc gactatggct gagtacgtag acgaatgggc tgccgcagga
     3121 cgtaagaaca tcttcggcga aacagtattg gtacaggaaa tgcaatctga aggtggtgct
     3181 gccggtgcag ttcacggttc tcttcaggct ggtgcattga ctactactta cactgcttct
     3241 cagggtcttc ttttgatgat ccctaacatg tacaagattg ccggtgaatt cttgccttgt
     3301 gtattccacg tttctgctcg tacactggct tctcacgcat tgtgtatctt cggtgaccat
     3361 caggacgtaa tgtcagctcg tcagactggc ttcgctatgt tggcagaagg ttctgtacag
     3421 gaagttatgg atttggcagg tgttgctcat ctggctacta tcaaatcacg cgttccgttc
     3481 atgaacttct tcgatggttt ccgtacttct cacgaaatcc agaagatcga aatgttggaa
     3541 aacgacgacc tcgctccgct gatcgaccag gaagctttgg ctgaattccg tgcccgcgca
     3601 ctgaatccga tgaagccggt tgcccgtggt atggctgaaa accccgatca cttcttccaa
     3661 catcgtgaat catgcaataa ctactatgaa gcagttcctg ctatcgtaga agaatacatg
     3721 aacgaaattt ccaagatcac aggccgcaaa tacggtttgt tcgattacta cggtgcagaa
     3781 gatgcagaac gcgtaattat cgcaatgggt tctgtaactg aagctgcccg cgaagctatc
     3841 gaccacttgg tagcaaacgg cgaaaaagta ggtatggttg ccgtacactt gtatcgtccg
     3901 ttctctgcca aacacttcct ggctgctgta cccaagactg caaagagcat cgcagtgctt
     3961 gaccgtacaa aagaaccggg tgctaacggc gaacctcttt accttgacgt taaagactgc
     4021 ttctatggcg cagaaaatgc tcctgttatc gttggcggtc gctacggtct gggttcaaaa
     4081 gataccactc cggcacagat catctctgta ttcgaaaact tggctatgcc aatgccgaag
     4141 aaccacttca ctatcggtat cgtagacgac gttacgttca cttctcttcc tcagaaagaa
     4201 gaaatcgctc tgggcggtga aggtatgttc gaagctaaat tctacggtct gggtgctgac
     4261 ggtacagtag gtgccaacaa gaactctgtt aagattatcg gtgacaacac cgacaaacac
     4321 tgtcaggctt acttctctta cgactccaag aagtcgggtg gtttcacttg ttctcacctg
     4381 cgtttcggtg atactccgat ccgttctact tacttggtaa atactccgaa cttcgttgct
     4441 tgtcacgttc aggcttacct gcacatgtac gacgtaacac gtggtttgcg taagaacggt
     4501 tctttcttgc tgaacaccat ctgggaaggc gaagaactgg ctaagaacct gcctaacaag
     4561 gtgaagaaat actttgcaca gaacaacatc tctgtatact atatcaacgc aactcagatt
     4621 gcaatggaaa ttggtctggg caaccgtacc aatacaatcc ttcagtctgc attcttccgt
     4681 atcacaggcg ttattcctgt agatcaagct gttgaacaga tgaagaaatt catcgttaag
     4741 tcttacggca agaagggtga agacgttgtt aacaagaact acgctgctgt agaccgcggt
     4801 ggtgaataca agactctgac tgtcgatcct gcttgggcta acctgccgga tgatgcaaaa
     4861 gcagaaaaca atgatcctgc tttcatcaac gaagtagttc gtccgatcaa tgcacaggac
     4921 ggtgacttgc tgccggtatc tgcattcaag ggtatcgaag acggtacttg gtatcaaggt
     4981 acttccaaat acgaaaaacg tggtgtagct gcattcgttc ccgaatggaa tgctgaaaac
     5041 tgtattcagt gtaacaagtg tgcttacgtt tgtcctcacg cttctatccg tccgttcgta
     5101 ctcgatgctg aagagcagaa gggtgctaag ttcgagcaac tgaaagctgt aggtaaagca
     5161 ttcgatggta tgacattccg tattcaggta gacgttctcg actgtctggg ttgcggtaac
     5221 tgtgccgaca tctgtccggg taatccgaag aagggtggca aggcattgac catgaaacac
     5281 cttgaaagcc agttggccga agctgataac tggacttact gcgctgaaaa cgtgaagagc
     5341 aaacaacacc tggtagacat caaggctaac gtgaagaact ctcagttcgc aactccgttg
     5401 tttgagttct caggcgcttg ctccggttgt ggtgaaactc cgtacgtgaa actgatttct
     5461 cagttgttcg gtgaccgtga aatggttgct aacgctacag gatgttcttc tatctactcc
     5521 ggttcagttc cttctactcc gtacactatg aacgaaaagg gtcacggtcc tgcatgggct
     5581 aactccttgt tcgaagactt ctgtgaattt ggtttgggta tggaactggc taacgaaaag
     5641 atgcgtgccc gtctggtgaa agtaatgaac gaagctatcg cttctgattg ctgcccggct
     5701 gaatacaaag aagtatttgc tgaatggatc aacaatatgc tggatgcaga aaagactaag
     5761 gaactggccg aaaagatcat tccgatggta gaagctgcta aggataaatg caaccactgc
     5821 aagcaaatcg ctgatctgca acaatatctt gttaaacgca gtcaatggat catcggtggt
     5881 gacggcgctt cttacgatat cggttacggt ggtcttgacc atgtaatcgc ttccggtaag
     5941 gacgttaaca tccttgtatt ggatactgag gtttactcta acacaggtgg tcagtcttct
     6001 aaagctactc cggtaggcgc tatcgctaag tttgctgctg caggtaagcg tgtacgtaag
     6061 aaagacctcg gtctgatggc tactacttac ggttatgtat atgttgctca gattgctatg
     6121 ggtgctgacc aggctcagac tctgaaagcc atccgcgaag ctgaagcata tccgggacca
     6181 tcactgatca tcgcttacgc tccatgtatc aaccacggtc tgaaagccgg tatgggtaag
     6241 agccaggaag aagaagaaaa ggctgttaag tgcggttact ggcacttatg gcgttacaac
     6301 cctgctttgg aagaagaagg caagaatccg ttccagctgg atagcaaaga acctaactgg
     6361 gaagacttcc aaggtttctt gaagggtgaa gttcgttacg cttctgtaat gaaacaatac
     6421 cctgctgaag ctgaagaact gtttaaagct gctgaagaaa acgctaaatg gcgttacaac
     6481 agctacaaac gtcttgccag agaaaactgg ggagctgata cagctgaata ataagtagaa
     6541 atactttgta cataataaaa ggcaggaatc ctggaaacag attcctgcct tttttgttta
     6601 tatattagaa gtaacgatta cttctcacga agatattcat taaaactcta aagatatgat
     6661 cggatttgtt atttggattg tcggtttgat actgactttc agagctgcca tagagatttg
     6721 gaatataaat gcggctgtag agaaaaggct tatagcgatt gtattaatcg ttcttaccag
     6781 ctggctggga ctacttttct actacttcta tggtaaagaa agaatggcgg gatggttgaa
     6841 gtagtgtttg cttatcaatc tttcttagga atccaactgt ttaccagttc ctgatgttct
     6901 tccatccatt gacgggcagc ctgtctttcc gtcgtctgcg cctcttccag agcagtcatt
     6961 aaagagctga tttccgcatc agtcagacga atattgccca gaagttcggc agcaaaagga
     7021 tctttctcgc taaaaccttt ccacgctatg gtatgaatgg tttccgcatt tccatatatc
     7081 agcttcgggt cctgaagaac tttcagtttg aaacggtcga acatccagtg aggcgtccat
     7141 cccgtcacga caatccagtc cttcttatca atcgctttct ttagggaagc agtcatggca
     7201 ggtccgctcg aagtcatcag tttataatcc aatccataat ctttgatggc ctgatcggta
     7261 gctttcataa taccggctcc ggcatcaatg ccgacaatct ggccagagaa acgttccttt
     7321 tccgcattca actcttcgat cgagttgatt gtaacgtaat ccggaaccac cagcccgata
     7381 cgggcaccat cataaatatc cccgataact tcgagtttat ctccgtattg tttcatataa
     7441 tcttccatag tgacaggcat ccagacatcc ataaatacgt ctgctttctt acgggagata
     7501 gaggtaaata taggtgcaag gtcggcattc agcaacttta catcgtaccc ctgatcttca
     7561 aaaatcgctt tggcaaggtt tgtcatggca atcccttccg accagttggc ataagcaata
     7621 cttatcttct tactctttcc gttgtctccg caggaaacga aggttaagag tataccggca
     7681 ataaacattg ccacaatcat ttttatctta ttcattgatt attcctttct ttggtgtgat
     7741 tcttatttct ttttactttt tctgttatct gccataccct gagtgatgcg gtccagtacg
     7801 atcgccaata tcacgactgc gataccgcct tcaaatccga gtccgatttt catttgtgtg
     7861 atacctttca gcacgatttc tcccaatcct ccggcagaaa tcatggcggc aatcactacc
     7921 atcgaaagtg acatcatgat cgtctggttg attcccgtca gaatagtagg caacgccaaa
     7981 ggcaattgca ccttataaag aagctgccag ggagtagctc caaaagaacg ggaggcttct
     8041 actacgtttt taggaacctg acgaatgccc agaccggtca gacgaaccac aggaggcatt
     8101 gcaaagatga tggtggcaaa agctcccggc acagttccca atccgaaaaa tagaacggca
     8161 ggaatcagat agacaaaggc aggcattgtc tgcataaaat cgaggacagg gcgcattatc
     8221 ttgttacaac gatcactgtt ggcagtccag attcctaacg gaacgcccaa aagcaatgcc
     8281 agacaggtgg aagaaagtac taatgccagt gtctgcatcg tttcttccca aaagcccatg
     8341 ccgtaaataa gtaataaacc taagagggta aatacggctg tccccttacc cgacttaaac
     8401 caggcgagtg cagccagcac tgcgattgtg atataaaaag gtattccaaa cagtacgtgc
     8461 tgaaaaccgt ctatgaatcc tccaatcccc atactgagag catcaaaaaa ggaagcaaaa
     8521 tgttctgtga gccaatttat ggctgtctct atatattgtc cgatatttat cataattcta
     8581 ttgcgttttg aatgatttca ttaatttctt ctttatcttt tcccgttact tcgatgatca
     8641 atgaggaaag tggcactacg ccttcaaact cccgattctc atttacgacc cagattggcg
     8701 agttcgtttt tgtcatcaac ggaagaatat cttccagcac cgtatccccc agtaccgaat
     8761 gaacttcatg tcttactaca gactcgatgg agcggatttg ctcttttcgc agtttcagca
     8821 agtcgttcaa ccgcacctct cctactaaca gattattgga atcgactacc ggaagaacgg
     8881 tcagattccg ttcgcgcatc ttacggatca gcacctccgg accttctttc ttcaaacgtg
     8941 ccactatggg tttatctacc ataactgagg aagccgtaat aatcttgctt cgatctacat
     9001 tctccacaaa tcgttctaca taagcgttgg caggttcggt caggatttct tccgatgtac
     9061 cgatttgtac aatttctcca tccttcatga tagcaatccg gtcgcccaat ttaatcgctt
     9121 cactcaggtc gtgagtaata aagacaatcg tttttttcat cttcgactgc aaagtcagca
     9181 gttcatcctg catctgtacg cggatcaaag gatcgagtgc cgagaaagcc tcatccatca
     9241 acaggacttc gggattattg gccaaagccc gcgccagccc gacacgctgc tgcatcccac
     9301 ccgacaattc actgaccatc tgattctcgt agcctttcag tcccaccagt tgcatacttt
     9361 ccatcgcttt ctgctcccgt tctccctttt taactccctg tagttcgagt ccgaaagcta
     9421 tattatgcaa gacagaacgg tgaggaagca gaccgaagtt ctgaaagacc atagccagtt
     9481 cttttcggcg aatctgcaac agttctttat ccgatacttt ggctatgtct gttccattga
     9541 taatcacttc tccggaagta gggcgtatca aacggttgat gcagcggagt aaagtggact
     9601 ttccactacc ggacagcccc ataatgacga atatttcgcc ttcattaatg gaaagattcg
     9661 catctttcac cgcaactgta catccggtcg cttttaatat ttcacttttt gttttacctt
     9721 ctttcaacat cttcaaagcc ttctgcttct cattgccaaa aaccagatag agatctttaa
     9781 tttctatttt actcatacaa taaaatggtt taggttatta aaataatata tacagcaaga
     9841 caagaacaaa cgataacagg aatttttctt tatatcgtat aaagttctga tttaaatacg
     9901 ggacaaataa caatgaatcc cgaaataatt aataaaatga ttattgacag actgagtaat
     9961 taaaaaagga atagaatttg ataagataat cctttcaacg aatagcaaaa aaatagcatt
    10021 tttatgtata aaaacagtct gttccagtat cttgctggca caaagataca aaaaacagat
    10081 taaacatgca aattatattc aaaatccggg gcatacagag gactttattt gtaatgatat
    10141 ggaaagtttt cgggtaatat tcccctatca ctcagcaaaa tagaacaaac cggcagataa
    10201 atataaaata agtttgaata tttcacctaa acaccgtata tttggcgtca ataactaaac
    10261 tagatttata tgttcaacag ggctattaca attttcctgg ggaaggataa ttgtcattac
    10321 acaacaaaag aaaaacaaac aggtactgcc acactagacg acaaaagcca agtacagttc
    10381 cttagtaaaa agaaccccaa aatgccgttt ttctatagtc ggcggaatct ctacatgata
    10441 ggtttcctgc tcgcttttat agtgactctg ctcgaattta tgcgaggacg gcatcaaaac
    10501 tttatggtct tctcagacgc tactcaattc ttctggcaag gcatcagccc atacacaacc
    10561 gaatttgtag aagctcacgg acgctacttc ctttattctc ctgttttcac ggtattgttc
    10621 gctccgtttg cgtatctgcc tgcatggctg ggacctttcg cgtggaatct attcaattat
    10681 tcattgtttt ttgtgacgat cttcacgctg ccccaacaat tcacccagca gcagaaatgc
    10741 cgtatgttcc tttttctgtt actgatttta ggacaaagtt tactttcatt tcagtataac
    10801 ataacagtag cctatttatt cttattcgcc tatacgttat tggaaaaaga ccggggattt
    10861 ctggctgttc tgttcatcat gatttcggga tgtaccaaag tatatggaat tttcgaactg
    10921 gcattgttgc tgtgctatcc tcacgtatgg cgtaactttg gctatgccgt tgcaatgggc
    10981 attgtattgc ttgcgttacc gttaatcaaa atagctcctg cagatttgct cccctattat
    11041 gaagaatggt gccatagtct tgctgttcat caatccaccg gagcttatga ttcatttttc
    11101 tatgcccgcc ccattgcagc atggacattg ccacatttcc gtgcacttca gataggaatg
    11161 ctcggtctgc tgactctgct ctttttgggg aatttccgca aatggtcgtc ttttgccttc
    11221 cgtgcccaag ctttgggcat tctcatgggc tgggtagtat tactgagtga ctccgccgag
    11281 aaacatacct atattatcgc attggcaggt ttcatgctct ggtattggag cagaccaaca
    11341 cgtaccgcaa cagacaagat tctattttgg tgctgttttg tgctgttatg tatcgttcct
    11401 atcgacatat tcgtccctgt tcccatcaga gatttcatta ccaggacctt atggcttcat
    11461 gtatgggttt tctttattgt atggatacgg atgatatggc ttaccttcct tgcatccttc
    11521 attcatccac gtgccacaaa tgttctttca gattaacgca tccgttagct ttgaaagaaa
    11581 cttcttctgc cagcaagagt tgtttttgtt ccccccaacc gggcaccagc cttccggtgg
    11641 aatttacaac tctatggcag ggaatggata attcatccgg cacttctttc aatgcacgcc
    11701 ccaccatccg cgagcattgg ggtgccccca agagcaaagc aatacctcca taagtagata
    11761 cttttcctac aggtatctgg gatacgactt cgtacacttc cttccgaaag gattcggaaa
    11821 agctctcttt atctacttta taatctttca tatatccctc tttacgatca caatgaaatc
    11881 atcctttcct tttcaggaaa tctgtcgggc tctctccaaa ctgctcttta tagcacttgg
    11941 cgaaataaga aggtgaactg aaaccgactt cataaccaat ctccgctacg gtcatgtccg
    12001 aagaagcaag caaagaagct gccttcttca aacgggcgat acggagcaat tcattcggag
    12061 agtagttagt caacgattta atcttgcggt aaagctgcac acggcttagt cccatatctt
    12121 tgcccaaatc ctccacattc aaaccggagt ctcccatttt ctcttcaatc aatgacttaa
    12181 atctttctac aaaatccttg tccatatcgc agacatcttc cttcgccaat gtctgcccgt
    12241 caccaaagaa ctgtttcaga cgacggtgag aatcaatcag attgcggaca cgtgccagca
    12301 acagttgtga actgaacggc tttgaaatat aagaatcggc accaccgtca tatccctgaa
    12361 tacgctgttc gtccagtgaa cacgccgtca gcagaataac cggaatatga caggtctgta
    12421 actcactttt cagccggcgg caacattcaa tgccatcaat gcccggcatc atcacatcgg
    12481 aaatgatcag gtccggaaca tacttcatag ccttacggat tccttcggag ccgtctgccg
    12541 cttcaatcac cgtatagtct gtatgcaaca gcgtatggac atacgaacgg atatcctcat
    12601 tatcatcaat aatcagtacg gacgatttgg aagagtcata tcctttttcc agttcttcct
    12661 cttccgccaa tagaacatct gttgtacggg aatccggaga aacaagggtg gtatccggtt
    12721 cggcagtaac agcctcgcaa gactgtacag gcagttcaac ggtaaagatc gtaccctgtt
    12781 tctcatcgct ctctacagag atcgtaccac cgtgcatttc tacgaaggct tttaccaatg
    12841 ccagtccgat tcccgaaccg gtatggtgca tatcgatctt atagaaacgg tcgaatacat
    12901 tgcggatatg ttcggcagaa atcatggaac cggtatttgc caccgtgaaa cgtatccacc
    12961 gtttatcctc tttactaagg gaagacagac ggacggcaat tttcccgttt tccggtgtaa
    13021 acttaaaggc attggacagg agattgaaat aaatacgttc cagcttctcc atgtctgcca
    13081 gtgtatgata atccgtatcc ggcatactat caaaagaaaa atggatatgc ttcttacggg
    13141 ctgccgcctg aaaagactca ttccatcctt cgaaagaaga aaggacatcc accgtaaccg
    13201 gagtatattc catcttgcca ttttcatatt tacggaaatc cagaatctga ttgaccagac
    13261 gcagaagaat gttcacattc cgctgaatca gcatgagcat ccggtgctga tctccgctca
    13321 gtgtcttgtc cgccaacaaa tgttctaccg gatcggcaac caatgtcaac ggagtacgga
    13381 agtcgtgaga aatattggtg aagaatacca gcttggcatg agtagcttct tccagttgat
    13441 gagaaagttg tatcaattgg tcacgctgtt cttccagttt gtcacgttgc tcttccaatt
    13501 gttgcttctg cttaaaaagt tctttattca agcgattctt tgagcggagt gatttataaa
    13561 cgaccaataa taagccggct accaataaaa ggataatcag actgccgtat aaaacgacct
    13621 gttgtgtagc tacctgagag agatagccac cgatacgtcc gttgagcgtt tcaatctttt
    13681 tgtcgagttc ggaaatgtgt gtggtctgca actgcatgac gtgtgcgttg gtacggtcca
    13741 caacagcggt attcatcacc gtttctttgg gatagggttt cttctccaga atatccatag
    13801 ccagttgcag taccttatca ccattggtcg gatagataaa ggtagcatcc agcacactgt
    13861 ccagaaccag ctccagcccg tttcccttac ccggcaaggc atctatgccg acaaaaatca
    13921 tttccttctc ccgccctgcc atctttgctg cctgataggc acccggagcg atacgatcat
    13981 tatgggcata cacagcatca atcttaggat gcctccgaag catactatcc atttctatct
    14041 ctgccggacc acgttcccaa gcagcatccg ctttatcaat cagctttata tccgggaatt
    14101 tactgatggc agccataaat ccctgatgcc gttccattgc aggagtcgaa ccgctcaatc
    14161 ctgtcagttc tactatattt cccttccctt tcagactgga ggcaatatag tttcctaccg
    14221 aacgaccgat ttcataatta tcggctccga tataggcagt atatttatcc gaaagaatct
    14281 tccggtctac aagaataacg gggatgcctt tctgataagc ttcttctaca atcggagtca
    14341 taggagcagc ttcgttagcg gaaataatca gcagatcgac tccttcgtcc ataaaataat
    14401 ggacatcttc cgcctgctta gtgttatcat cccctgccga acggatttcc accgaaacac
    14461 cattataaaa cattgcttcc cgaagaatct catcattcat cttatgtcgc catgaatcat
    14521 cgctgcattg agccacccca atacgaaaat ggggtgtatc ctgccggcaa gccgtcatcc
    14581 cgattaaacc aaacagcacc agcatccact tcagatatct catcgtcttc atccatctca
    14641 tcatttcata gttctttctg taatccaatt aagaacaaaa ataagaaata atactgtaaa
    14701 gttctctaac ttcagctatt tattattcta aaaagaagga aagcagtcct ctttcagacc
    14761 atcggaaagt attaacaaaa gtataaagcg taaaacaaac acttaatcaa tgttataaaa
    14821 catagcgttt tacttggata atttgcagat ttcacagaag tccgtatctt tgcactgtgt
    14881 ttttcatagt attagattta aggttaacaa aggttggagc aaggcgttgc tccttttttt
    14941 atgccctgac ctttcatcta ccggttagtt ttcatcccat tccttttcca gtttaccatc
    15001 aatagtgtag cgtttccatc gtcctacacg gcgaccattc ttatattccc cacattcacg
    15061 aagctggtca ttctttacat aacgagcttc gaacggtccg ttctgccttc cgttcacata
    15121 ggtagaagtt tcccaataat caaagcggtt gctcactatc agccgtcgtt ccttgccatg
    15181 caatctgccg gcctgatagg tagcttcata tctcaattca ccattttcca gattatattc
    15241 acggtataaa ccgtctttac gatcgttctt catataatat tctttctgcc ttaccccact
    15301 tccgttggca aatgagacat ggagtccatc ttcttttcca tccagatagg tttcaatcat
    15361 cagcgtatct ccgctttcag caaaagtagt ccaccgacca ttcttctttc cattcttata
    15421 actacccagt atacgtggcg agccaaacgt aaacacggac gaatattcac cgtcctgcaa
    15481 accttcttca ttgaaataaa cggtctcata caaatcatat gtacctttca gaaaagtata
    15541 ctgtttgcct acctgcttcc cgtccttgta attatgctct ttccgcaaag taccgtcaga
    15601 ttcgtacgac agttgcttcc cgtgctcttt ccccatccgg aagtttcttt cactttccac
    15661 ttttccggta gtaaagtaac ttttgctcgt accgtccagc ttaccttcct tataggactt
    15721 ttcttctttc agcttaccgt caaacttgga gttaatcttg aagaggccat ccttccgccc
    15781 ttctttataa cttccttccg ttattaatat attgtccaca tattctttgt atccgccatc
    15841 ataaaaacca tctttaaaag atgccagcac ataggcggaa tgataaccat ctatgatgcg
    15901 atgttcgcca ttcaatgctt tttccgtttt cagttcctga aacaacagtc tgccatcgcc
    15961 tacattaaca acagatacct gatcgatctt atattccttt tgcgcaaaca aaggaagagc
    16021 aagatataaa aacaaaaata cgttccagct ttttgatctg aggaagttcg aaatgtgttt
    16081 cataaagtag ttttctcttt ttgatttatt atttaaaaac ctgccgcaaa gataggcaat
    16141 cggcttataa aacaaggcaa ggaagagggg gacaattaaa aaaaagaaca tctgttatta
    16201 tcattctaat aattaacaga ttaagtagta aatcaaaaca cagggaaggg ggacatttac
    16261 tgaaataaga aacagaaaag aagatgtgtc aaaagcaact aaactctcct ccttcctgaa
    16321 ggaggggaat ttagttgctt ttgacacatc ttctttttga atttaaagag attctacaac
    16381 aatctgtctt tcagaacaac cggaagttcg ggcattgcac cgctctgcgt acaaacataa
    16441 gcggaaactt cgacagccag cttatgagct tcgggaacag acttgccatt cagaatggaa
    16501 gcacagaaag cggcagtaaa ggaatccccc g
//
