LOCUS       c00046_gnlPro..        15347 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BJFDICKD_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:45:24
            Original ID  :: gnl|Prokka|BJFDICKD_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15347
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..186
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="EKKYVYGILGIAKLFGCSLPTANRIKKSGKIDKAITQIGRKIIVD
                     AELALELAGKKTGGRK"
     protocluster    1..15347
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7346:10317]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7347..10317
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15347
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15347
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             201..1277
                     /locus_tag="ctg46_2"
                     /transl_table=11
                     /translation="MDYMKDIREISDEQAIILWQASRLSLSKSYEKAPEILKVHDSVIG
                     TLGNFSASIGKAKSKKTFNVSAIVAAALKNGTVLRYVAELPEDKRKVLYVDTEQSPYHC
                     LKVMTRILRMAGLPDDRDNENLEFLALRKYTPEQRIRIVEQAIYNTPEIGLVIIDGIRD
                     MVYDINSPSESTRIISKLMQWTDDRQIHIHTILHQNKGDENARGHIGTELNNKAETVLQ
                     VEKDKGNGDISHVSAIHIRAMDFEPFAFRINDKALPELIEGYKPETKKPGRPEEEKFDP
                     YRHITEQQHRIALEAVFGLKEEYGYKELEDALIKTYMSVGVKLNHKKAVSLITMLRNKR
                     MIVQETGRKYTFMPDFHY"
     CDS             1490..2446
                     /locus_tag="ctg46_3"
                     /transl_table=11
                     /translation="MDIQTAKQIRIADYLHSLGYSPVKQQGVNLWYKSPLREEAEASFK
                     VNTEREQWYDFGLGKGGGIIELAAHLYATDHVPYILKRIAEQTPHVRPVSFSFGKQNSS
                     EPSFQQLEIVPLSSTALLAYLQGRGINIKLAKRECSEARFTHNGKRYFAIAFPNGSCGY
                     EIRNRYFKGCIAPKEISHIRQSGKARNTCYVFEGFMDYLSFLTLRQESCPNYPELDGQD
                     YIVLNSVSNVNKALYPLGNYERIHCFFDNDHAGLEALRQIRMEYGRDRYIRDASQIYRG
                     CKDLNEYLQKQIERKRQLQSAKGVRSQSPEKKNGFQL"
     CDS             2658..4061
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="MATKSSIHIKPCNIASSEAHNRRTAEYMCNIGESRIYVVPELSTD
                     NEQWINPDFGTPELRTHYDNIKQMVKEKTGRAMQEKERERKGKNGKIIKVAGCSPIREG
                     VLLIRPDTTLADVRKFGEECQRRWGITPLQIFLHKDEGHWLNGQPEAEDKESFQVGNRW
                     FKPNYHAHVVFDWMNHETGKSRKLNDEDMATMQTLASDILLMERGQAKAVTGKEHLERN
                     DFIIEKQKAELQRIEETKRHKEQQVSLAEQELKQVKAEIRTDKLKKTATNAATAIASGV
                     GSLFGSGKLKELEHHIEQLHQEITKRDKATDELKIQIQQIQEQHSRQIRNLQRIHNQEL
                     EAKDKEISRLSTLLEKAHKWFPMFKEMLRMEKLCAVIGFTKDMIENLLTKKESIQCSGK
                     IYSEEHRWKFDIKNDIFRVEKHPMDSGKLMLTINRQPIVQWFKEQWEKLQQNLRNSVQR
                     EQKSRGFRI"
     CDS             4150..4503
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MKPKEVLEKWIDCFNKADAYHIAELYATNAVNHQVANEPIIGKES
                     IYKMFVNEFATAKMVCMVENIFEDGEWAIMEWKDSLGLRGCGFFHVKDNKIVFQRGYWD
                     KLSFLKQHNLPIE"
     CDS             complement(4732..4941)
                     /locus_tag="ctg46_6"
                     /transl_table=11
                     /translation="MTEKQIVWYILLTEVKIDSDTQSVTSLSVAPLAVLPEFQRKGIGG
                     GDVDSVSPSEGSTFGLRHSSRIGA"
     CDS             complement(4952..5464)
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="MTKKEHTTITELFQVLDLLESLNMQFWLDGGWGVDVLYGQQTRLH
                     RDIDIDFDANYTDQLLDLLQERGYQIETNWLPTRVELYSKELGYIDIHPFVLNADGTSK
                     QADLDGGWYEFQPDYFGTAVFEGRSIPCISAKGQQVFHSGYDLREKDIHDLSIIKQCIT
                     TMSLTIR"
     CDS             complement(5489..6694)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 94.2; E-value: 2.6e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg46_8"
                     /sec_met_domain="MFS_1 (E-value: 7.5e-30, bitscore: 94.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHWKSTLAVIGIGQLISILTSTIVGFSIIFWISNEFKSPTALSL
                     AILAGFLPQFVLGLFAGVYVDRWNRKKTMFYSDLFIAFCTLCLFIVITKGYKDLSFFYL
                     LTACRSIGSTFHAPALQASIPLLVPKHHLVRVSGLYHSIQSFSEVIAPVVGASLVVWLP
                     IQYILLIDVIGAVAACLTLLCVQIPSLQKTKVLPDFKKELTECWHTLRRTMGILPLFVC
                     FTLVTFVLMPVFTLFPFMTLLHFNGNILQMGVVEMGWGSGALLGGLVLACKALKSKQTL
                     VMHTAYVILGLYLISASYLPSSAFIGFVCLTFTGGIAYSIYHALFIAIIQQNLASDMLG
                     RTFSLIFSLSTFPSMLGIVASGYWVEAWGITSVFMISGWVIFLIGVGANFISSIKQLDN
                     YA"
     CDS             7347..9575
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_9"
                     /sec_met_domain="Gly_radical (E-value: 3.4e-46, bitscore:
                     146.5, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1174.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLRRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYNAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             9589..10317
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73.7;
                     E-value: 6.1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_10"
                     /sec_met_domain="Radical_SAM (E-value: 1.3e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFKLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQGKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10310..10759)
                     /locus_tag="ctg46_11"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(10746..10913)
                     /locus_tag="ctg46_12"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDKVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(10973..11476)
                     /locus_tag="ctg46_13"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVLTRAVAQAGAGDDGGEDPDKNPGSGGDGSGDEEAP
                     DPTV"
     CDS             11670..11900
                     /locus_tag="ctg46_14"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             11987..14101
                     /locus_tag="ctg46_15"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYVIAEMTEEEIVSTISSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYMGHIVIDIDHLSKEELARILPVIKRC
                     NYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLFGSKQQTPPDGTPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETVSLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRRPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTNHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMAKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(14171..14476)
                     /locus_tag="ctg46_16"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(14457..14789)
                     /locus_tag="ctg46_17"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             14806..14964
                     /locus_tag="ctg46_18"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPPKVRGVREELKLFLFYFFISTFYIS
                     LKKKYEC"
ORIGIN
        1 gaaaagaagt atgtgtacgg aatactcggt atagccaaac tgttcgggtg cagtctgccc
       61 actgccaacc gcataaagaa aagcggtaag atagacaagg cgattaccca gatagggcgc
      121 aagattatcg tggatgcgga acttgccctt gaactggcag ggaagaaaac aggcggacgc
      181 aagtaacggg aggaatcgct atggactata tgaaagacat ccgggaaata tcggacgaac
      241 aggcgataat tctctggcaa gcctcacggc tgagcctgtc gaaaagttat gagaaagcac
      301 ctgaaatcct taaagtacat gattctgtca ttgggacatt gggtaatttc agcgcatcca
      361 tcggcaaagc caaaagtaaa aaaacgttca atgtatcggc tatcgtagcc gctgcattga
      421 agaacggcac agtgctgcgg tatgtggctg aactgcctga agataagcgg aaagtgcttt
      481 atgttgatac agagcaaagc ccttaccatt gtctgaaagt catgacgcgc attttgcgaa
      541 tggctggttt gccagatgat agggacaatg agaatcttga atttcttgcc ttaagaaaat
      601 acacgcctga gcagcgtatc aggattgtgg aacaggctat ttacaataca cccgaaatcg
      661 gtcttgtaat tatagacggc atacgggata tggtgtatga catcaacagc cccagtgaat
      721 caacacgcat catatccaag ctgatgcagt ggacggacga caggcagata catatccata
      781 cgatactgca tcagaacaaa ggggatgaga acgcaagagg gcacattggt acggagttga
      841 acaacaaggc ggaaaccgta ttgcaggtag aaaaggacaa gggcaacggt gacatcagcc
      901 atgtttcagc cattcacatc cgggcaatgg actttgagcc tttcgcattc cgtatcaacg
      961 acaaagccct tcccgaactc attgagggat acaaacctga aacaaagaag ccgggaagac
     1021 ccgaagaaga gaagttcgac ccttacaggc atatcaccga gcagcagcac cgtatcgcat
     1081 tggaagccgt tttcgggctg aaagaggaat acggctacaa ggaactggaa gatgccttaa
     1141 tcaagaccta tatgtcagtg ggtgtaaagc tgaaccataa aaaggcggta tcgctcatca
     1201 ccatgctccg caacaaacgg atgatagtgc aggagacagg cagaaaatac acattcatgc
     1261 ctgacttcca ctattagccc atttccctgc aatcacttca ctttattctc ggggtgtata
     1321 tattaggaat atagtgaagt gcttggggaa tgggactaaa tcacttcact ttattaccgt
     1381 atcctatata tacgagaatt tagtgaagtg attatagacc gtacttccta aaaaggtacg
     1441 ggcaaaaaga aaaataaacc aattcaccaa ctactaaaac aatcatttta tggatataca
     1501 gacagccaag caaatcagaa tagcggatta tctgcatagt ttaggatatt ctcccgtcaa
     1561 gcaacaaggt gtcaatctgt ggtataaatc accgttaagg gaagaagccg aagcctcgtt
     1621 caaggtaaat accgaacgtg aacaatggta tgacttcggt ttgggtaaag gtggtggtat
     1681 catagaactg gctgcacacc tgtacgctac cgaccatgta ccttacatct tgaaacggat
     1741 agcagagcag acaccgcacg tgcgcccggt atctttctct tttggaaagc aaaactcttc
     1801 cgagccgagc ttccaacagt tggagattgt tccgctgtca tctactgccc tgcttgccta
     1861 cttacaaggt agaggaatta acataaaact ggcgaaaaga gaatgtagtg aagcacgttt
     1921 cactcacaac ggcaagcggt actttgccat cgcctttccc aatggttcgt gtggatatga
     1981 aatccgcaac cgctatttca agggctgcat cgccccaaag gaaatctccc acatcaggca
     2041 gtcgggaaaa gcgaggaata cctgttatgt gttcgaggga tttatggact acctctcctt
     2101 tttgacattg agacaagaga gctgcccaaa ttatccggaa ttggacgggc aggactacat
     2161 tgtattgaac tccgtatcga atgtaaacaa ggctctctat ccgttgggca attacgaacg
     2221 catccactgc tttttcgaca acgaccatgc aggactggaa gcactccggc aaatccgcat
     2281 ggaatacggc agagatcggt acatccggga cgcttcgcag atttacagag gatgcaagga
     2341 cttgaacgaa tacttacaga aacagattga aagaaaaagg cagctccagt ccgccaaagg
     2401 ggtgcgcagc caatcaccgg aaaagaagaa cggcttccag ttatagccca ctataactac
     2461 acgcttcgct ttcgtagttg tgggctctcc cgaggggatt agggctttgc cctaatgacc
     2521 cactcagggc gtttcacccc tgagaacccc gagcaaagag tgaccctctc tttgcaatct
     2581 ccgcttatgg gttaccccta agaacccctc tgcgaaagcg agcaaagtaa atcaattgta
     2641 aacaaaggaa agaagctatg gcaacaaaat caagcataca tatcaagcct tgcaacatcg
     2701 catcgagcga ggcacacaac cgaaggactg ccgagtatat gtgtaatatc ggggagtcca
     2761 gaatctatgt cgttcccgaa ctttccaccg ataacgaaca gtggataaat cccgacttcg
     2821 gcactcccga actgcgaact cattatgaca atatcaagca aatggtcaag gaaaagaccg
     2881 gacgtgccat gcaggaaaag gaaagggaac gcaagggaaa gaatggaaag attatcaagg
     2941 tggcgggatg ctcacccatc cgtgaaggag tattgcttat cagaccggac accacactgg
     3001 ctgatgtacg caaattcggt gaagagtgcc aaagacgctg gggcatcact ccgctacaga
     3061 ttttcctgca taaagacgaa gggcattggc tgaacggtca gccggaagca gaagacaagg
     3121 agagcttcca agtcggtaac agatggttca aaccaaatta tcatgctcat gtcgtattcg
     3181 actggatgaa ccatgaaact ggaaagagcc gaaagctcaa tgacgaggat atggcaacca
     3241 tgcagaccct tgcttccgat attctcctga tggaacgtgg acaggcaaaa gctgtcacag
     3301 gtaaagagca tctggaacga aatgatttca tcattgagaa gcagaaagcc gaactgcaac
     3361 gtatagagga aaccaagcga cacaaggaac aacaagtaag ccttgccgaa caggaactca
     3421 aacaggtaaa agcagagata cgcacggaca aactaaagaa aacagccacc aatgctgcta
     3481 ccgccatagc aagcggtgta ggttctcttt tcggaagcgg taagctgaaa gaactggaac
     3541 atcacatcga gcagctacat caggaaatta ccaaacggga caaagctact gatgaattaa
     3601 aaattcagat acaacaaata caggaacagc atagcagaca aattcgtaat cttcaaagaa
     3661 tacataatca agaacttgaa gccaaagaca aggaaatatc acgattgagc accttgcttg
     3721 aaaaagccca caaatggttt cccatgttca aagagatgtt gagaatggaa aaattatgcg
     3781 ctgttatcgg gtttaccaaa gacatgatag aaaacctctt gacaaagaaa gaatccatac
     3841 aatgtagtgg caaaatttat tccgaagaac acaggtggaa atttgacatc aagaatgata
     3901 tttttagggt tgagaaacat ccaatggata gtggtaagct tatgctgacc ataaaccgac
     3961 aacccatagt acaatggttt aaggaacaat gggaaaagtt acagcagaat ctacgtaact
     4021 cggtgcagag agagcaaaaa tccagaggat ttagaatata gaatagccta ttattaataa
     4081 aatcaagtat ctatgcatcc aaacagattg tttttattac agaatcaaaa tcctaagaat
     4141 ttataaaaaa tgaagcctaa agaagttttg gaaaaatgga tagattgctt taacaaagca
     4201 gatgcttatc atatagcaga gctgtatgct actaatgcag taaatcatca agtcgcaaac
     4261 gaaccaataa taggtaaaga atcaatctac aaaatgtttg tgaatgaatt tgccactgct
     4321 aaaatggttt gtatggtgga aaatattttt gaagatggcg aatgggctat catggaatgg
     4381 aaagactctc ttggacttcg tggatgcgga ttttttcatg taaaagataa caaaatcgtc
     4441 tttcaaagag ggtattggga taaactttca ttcttgaagc aacacaatct tccaattgaa
     4501 taagtactat cagaatacgg actgggaaat tgaaataccc agtccgagtt atataatgaa
     4561 ttttacttgt taaactattt aaagtcagtt ggataacaaa ccataccttt cacattctca
     4621 gtagctccag gtattaattc agccaccatg caatattcat gagagacttc gaaaggaaat
     4681 tcaattccta aatcgatagc cttgcgatag ccaaatcgag gataatactc tttatgcccc
     4741 aatacgactg ctgtgccgta acccaaaagt gctgccctct gatgggctta ctgaatcaac
     4801 atcccccccc ccaattccct tacgctggaa ttccggcaag actgccaatg gagctacact
     4861 cagggatgtg acagactggg tgtcactgtc tatctttact tctgtaagta agatatacca
     4921 gacaatttgt ttttctgtca ttttcttgtt cttatctaat tgttaggctc attgttgtta
     4981 tacattgttt aattatagat aaatcgtgaa tatccttctc tcttaaatcg tagcccgaat
     5041 ggaatacttg ttgccctttt gcagaaatgc aagggatgct tctgccttca aagactgctg
     5101 ttccaaaata gtccggttga aattcatacc agcctccatc caagtcggct tgtttggaag
     5161 tgccgtccgc attcaagaca aaaggatgga tatcaatata gcctaattct ttgctataca
     5221 gttccacacg ggtgggcaac caatttgttt caatttgata tcctctctcc tgcaaaagat
     5281 caaggagttg gtctgtataa ttggcatcaa aatcaatgtc aatatctcta tgcaagcggg
     5341 tttgctgtcc gtacaagaca tccactcccc agcctccatc caaccaaaac tgcatgttca
     5401 ggctttccaa caagtccaaa acttgaaata actctgtaat cgtagtgtgt tctttctttg
     5461 tcatataata attctttaat aaataatact atgcgtaatt atccaactgc ttgattgaag
     5521 aaataaaatt tgcacccact ccaatcagaa agataaccca tccgctgatc ataaagacgg
     5581 atgtgatacc ccatgcttcc acccaatatc ctgaagctac gatacccagc attgatggaa
     5641 aggtactcaa actaaagatg agagaaaaag tccgtccaag catgtccgaa gccaagttct
     5701 gctgaataat agcgatgaaa agcgcatggt aaatggaata ggctatgcct cctgtaaatg
     5761 ttaggcaaac aaaacctata aatgcgcttg atggtaaata actggcgcta atcagataca
     5821 atcccaatat cacataagcc gtatgcatca ctaatgtttg cttgcttttc aaagccttac
     5881 aggcaagtac taaaccgccc aacaatgccc ctgagcccca acccatttcc acaactccca
     5941 tttgcaaaat gtttccgttg aaatgcagaa gcgtcataaa aggaaataac gtaaaaacag
     6001 gcataaggac aaaagtcacc agcgtaaagc atacgaataa aggcaaaatg cccattgtac
     6061 gccgcaaggt atgccaacat tccgtcagtt cttttttgaa atctggaaga actttcgttt
     6121 tttgaagaga aggaatctgg acacaaagta aggtcagaca agcagcaaca gctccgatca
     6181 catctatgag cagaatatac tgtatgggaa gccaaacaac gaggcttgcc cctacaacgg
     6241 gagctatcac ctcactgaag gattgaatgg aatggtacaa acctgatacc ctgacaagat
     6301 ggtgcttggg aaccagtaaa gggatgcttg cctgtaaagc aggtgcatga aacgtactgc
     6361 ctattgaacg acaagcagtc aatagataaa aaaaagaaag gtctttataa cccttggtta
     6421 tcacaataaa aagacatagg gtacagaacg cgatgaacaa gtccgaataa aacatcgttt
     6481 tctttcgatt ccatctgtca acatagaccc cggcaaacaa gcctaataca aattgtggta
     6541 aaaatccagc taaaatagcc agagataaag ctgtcgggga tttaaattcg ttgctaatcc
     6601 aaaaaataat ggagaagcca acaatcgtac ttgttaaaat agatatgagt tggcctattc
     6661 ctatcacggc caaagttgat ttccaatgat tcattgtgct aatatttcat gcgtttatag
     6721 ataagtactt tcgtacatta agcaaaacga aattctatcc acacaaaaaa cttgtattat
     6781 aatccactcc tgacgttgga atacaataac aaatactttc aggacgatgt aaaatcctga
     6841 aaaatcaaac tgaatggata gataaatatt agtcttttct catcggattc ttttaatatc
     6901 gctactcttt tattatgtag tggttgtatt atcttaaata aaacaaaaac acccgacttt
     6961 acattcttgg gtgtaaaact gggtgtttgt tttacaatct gctgattttc agcgtttgtt
     7021 gcggagagac agggattcga accccgggta cctcgcagta caacggtttt caagaccgcc
     7081 gcaatcgacc actctgccac ctctccaaaa cttccttatc agaagtgctt ttcgttaaaa
     7141 gcggtgcaaa ggtacaaaga tattttaaac ccgcaagagt tttcactaaa aatttaatct
     7201 aatcttttcc taaggatagc aattaatagg tattttatgt tgaaaagcat aaaatagagc
     7261 atatttatgc cgattatatg aaaaatgatt gtaactttgt gcgctctaaa gaataggata
     7321 actacaacct ctaattttat cattttatgg aattaaacaa gatctttaaa gacggtcttt
     7381 ggagcagcga aatcaacgtc agagatttcg taagtcataa catcactccg tattacggag
     7441 atgcttcatt cctcgaagga cctacagaac gtaccaaagc cgtatggaac cgctgcctcg
     7501 aagcgttggc agaagaaaga gaaaacaacg gtgtccgctc attagataat gttaccgtat
     7561 caaccatcac ttcccacaag gccggatata tcgacaagga aaacgaactg atcgtcggcc
     7621 tgcagacaga cgaacttctg agacgtgcca tcaagccttt cggaggtatc aacgtagtca
     7681 gcaaagcctg tcacgaaaac ggtgtggaag tggacgaccg cgtaaaagat attttcactc
     7741 actaccgcaa gacgcacaac gacggagtat tcgacgtgta tacggaagaa atccgttcct
     7801 tccgttcgct gggattcctc accggacttc ccgacaatta tgcacgcgga cgtatcatcg
     7861 gtgactaccg ccgtatggct ctttacggca tcgaccgtct gatcgaagca aagaaggaag
     7921 atttgcataa cctcaccggt ccgatgacag aggcccgtat ccgtctgcgc gaagaagtgg
     7981 cagaacagat caaggcactg aaagacatga aagtgatggg cgaatactac ggtctcgacc
     8041 tgagccgtcc cgcttacacg gcacaagaag ccgtacagtg ggtatatatg gcttaccttg
     8101 ccgccgtcaa agaacaagac ggtgccgcca tgtcactggg taacgtttct tctttcctcg
     8161 atatctatct ggaatatgaa ctgagcaaag gaaccatcac cgaatcgttc gcgcaagagc
     8221 tgatcgacca gtttgtcatc aaactgcgta tggtccgcca cctgcgtatg caatcataca
     8281 acgacatctt tgcaggcgac ccgacctggg taaccgaatc tctgggcgga cgtctcaacg
     8341 acggacgtac caaagtgaca aagacctcct tccgtttcct gcagacattg tacaacctcg
     8401 gcccttcacc ggaaccgaac ctgaccgtac tctggagccc ggaacttccc gaaggattca
     8461 aagaattctg tgcaaaggtt tctatcgaca cttcttctat ccagtacgaa aacgacgacc
     8521 tgatgcgtga agtacgtcag tccgacgact acggaatcgc ctgctgcgta tcataccagg
     8581 aaataggcaa gcagattcag ttcttcggtg cccgttgcaa cctggccaaa gccctgttgc
     8641 ttgccatcaa cggcggacgt tgcgagaata ccggtacagt catggtgaag aacatccccg
     8701 tactgaccag tgacacgctg aagttcgaag aagtaatgga caactacaag aaagtgttga
     8761 ccgaaatcgc ccgcgtatac aacgaagcga tgaacatcat ccactatatg cacgacaagt
     8821 attactacga gaaagcccag atggctcttg tagatacgaa cccgcgcata aaccttgctt
     8881 acggtgttgc cggactttcc atcgcactcg actcactgtc tgccatcaaa tatgcgaaag
     8941 taactgcccg ccgcaacgat atcggcctga cagaaggttt cgacatcgaa ggagaattcc
     9001 cttgcttcgg taacgacaac gacaaggtag accaccttgg cgtagacctg gtatacttct
     9061 tcagcgaaga attgaagaaa ttgcctgttt acaagaatgc ccgtcctacc ctctccttgc
     9121 tgactatcac ttccaatgtg atgtacggca aaaagaccgg tgctactccc gacggacgtg
     9181 ccaaaggtgt tgccttcgct ccgggtgcca acccgatgca cggacgcgac aagaatggtg
     9241 cgatcgcttc tctgagctct gtagcgaaac ttcgttaccg tgactcacag gacggtatca
     9301 gcaacacctt ctctatcgtt ccgaaatcac tgggtgctac ggacgaagac cgtatcgaga
     9361 acctcgtaac gatgatggac ggttacttca ccaaaggtgc ccaccacctg aacgtaaacg
     9421 tactgaaccg tgatatgcta tacaatgcca tggagcatcc ggagaactat ccgcagctga
     9481 ctatccgagt ttccggttat gccgtaaact tcgtgaagct gagccgcgaa caccaactgg
     9541 aagttatcag ccgtagcttc cacgaacgta tgtaatctat tactctatat gatgataaac
     9601 gtacattcat acgaaagtat gggaacattc gacgggccgg gcttacggct cgtcgttttt
     9661 cttcaaggat gcaacttccg ctgcctctat tgcgccaatc cggatacgat agcaggaaag
     9721 ggaggcacac ctaccccacc ggaagaaatc gtccgtatgg caatgagcca gcgccctttc
     9781 ttcgggaaac gcggaggaat cactttctcc ggaggcgaac cgacgtttca ggcgaaagca
     9841 ctcgtcccgc tggtccgcga actgaaagaa aaaggcattc atgtctgtct ggacagcaac
     9901 ggaggacttt ggaacgaaga cgtagaagaa ttattcaagc tgaccgacct tgtgttattg
     9961 gatataaagg aattcaaccc caaccgccat cagacgctga ccggaagaag caatgaacag
    10021 accatccgta cggccgcctg gctggaagaa cagggaaaac ctttctggct gcgttatgtg
    10081 ctagtgcccg gatacagcga ttttgaagaa gatatacgag cactgggaga agcactcgga
    10141 aaatacaaga tgatccaacg ggtggaaata ctgccttacc atacactggg cgtacataag
    10201 tacgaagcga tgggacagga atacaagatg aaaggggtaa aagaaaatac ccccgaacag
    10261 cttgaaaaag ctgcggaggt attcaaagag tatttcacta cggtggtagt taattaatgg
    10321 agaattctcc aatgacctca aagcaagggc attctttaat ccgttcccaa ggatctacaa
    10381 tcccattata gttggtgtcg ggacttaagt cccgatgacc tactacctta gcttccggat
    10441 aacgctgcaa caattcgtgt accaaacgat gtaacgcctc cttctgacgg ggtgtacgcg
    10501 tatccgccgc ttttccattc tcatccaaac cgccctcata gcatacacct aaactgatcg
    10561 cattgtagcc acgtgcatga gccccgaccg tatcttcatc ccgcatcggc tcaatctcgc
    10621 ccgacttgcg tatataataa tgatagcccc agcacgaaaa gccacgataa cggtgagccg
    10681 tatccacatc ctttgccgta aagtcgcaat cgacacgggt ggcggaacaa tggatcacga
    10741 tcagactaat ctttctcatg ttccttttcc ctttccgtcg ttttcacttt gcacacctcc
    10801 ttacaagtag tatgatagcg cacttctctc accaccttgt cccgctttct ctttccgaag
    10861 aaaggaatca gatacatgat cacatctaaa atccggttta ctatttcttt cattttatca
    10921 aaatattaat ggaagttatt ctaattcgtt attaccttga cccgtctgcc aattataccg
    10981 tagggtccgg agcctcttca tcgccggagc catcaccgcc ggaaccgggg ttcttgtcag
    11041 ggtcttctcc cccgtcatcg cccgcacccg cctgcgccac cgcacgagtc agcacttgct
    11101 gataactcag aatcttcatc aactccgcca gcgtcttacc ggggcggaaa ataagatgcg
    11161 cccccttaat catcgaaccg gaaaactcct tgaccgatgc cgcaccttca ctgttcagcc
    11221 ctatctgcaa actgcccaaa tcgcccagtc tcgcaattct tcctgccttc aacgcacgct
    11281 tcacttcgta aagaataccc gaaatagccg cacgtacatc cgtttccgta caagtagaac
    11341 gactggtgat cgcttcgcac aactcttcaa agtccaactc ccccgacgcc tgcgcctgtg
    11401 cataatactt tgccggttcg ctcttttttg caggattctt gcgcggcacc actgaataag
    11461 atactgtcat tgccataata aaataatttt aaagtttata atacgtagga tgcatccctt
    11521 tcttgttaac agcacaaaga taagggtatc cggacaagcc atattcccca acgaagtttc
    11581 ttgatttcca acgaataaaa acgaagtcaa acctttgaaa aacaataaat tttatgtaac
    11641 tttatagcat aaaacaagaa gaaaacatca tgaattacaa agaagattct ttccttatcc
    11701 gcacctatac caaagcggaa ctggctcacc tttacaatcc ccatgtctgc ctcaaagttg
    11761 ctttacaaat acttcgtcgt tggattattt acaacctccc tctcctgcac gaactcgaac
    11821 aggaaggtta ccgcgcacgc aaccgcctcc tttcgccgaa acaagtggca actatcatac
    11881 actttttggg cgaaccgtag taacttattg ccattctata caaagttcct ttacacattt
    11941 ccgcaaagaa gttcttttgc actgacaaaa aacaattaaa atcaaaatga aacatttcac
    12001 catatttcaa ggtttctact acgtaatagc agagatgacc gaagaagaaa tagtgtccac
    12061 tatcagcagt tttacctacc gggaaaaagt cgaagaaata cgccgcatct ttgcagagca
    12121 aggagaaaag gctgccaatg agaagaaaaa agaattgccg gcaatcgcct tctccgccag
    12181 ctaccgaggg aggcgtacca aagtgaatct cgtcaaatat atgggacaca tcgtgataga
    12241 catcgaccat ctcagcaaag aagaattggc gcgcatcctc cctgtcatca agagatgcaa
    12301 ttacacccgt atcgctttta tcagtcccaa agggatgggc gtgaaaatca tagtgcgtgc
    12361 atgccatccg gatgagacat tgcccgaaac ccttcaggaa atagaagact tccatcatgc
    12421 agcttacacc agactcgttt ctttttacac cgaactctgt cagatagaaa tcgacacctc
    12481 cggccaggat gtggcacgca cttgtctgtt ctcttacgat ccggagattt atttcaatcc
    12541 gaacgctgac gcttttcttg tagatcaacc tcaggcatcc tacaaggttt caaatcgtaa
    12601 aaatctcttc ggcagtaaac aacagactcc tccggacggc accccgacga atgaagacac
    12661 agcgctcaac gcccattccg ccaacgcttc tctggtgctg actttaacct actatcacaa
    12721 caagtccgaa aaatacatag caggcaaccg gaacaattat ctgcaccatc tctcatgtac
    12781 cttcaatcgc tacggcattc cgcaggagga agcatccgcc tttatcaaaa gccagtttac
    12841 agactttccg gcagacgaga cagtctcttt gatcaatagc gcctacgctc ataccgacga
    12901 atttaatacc tgtaagctga atggcacgca gaaacgaata ttacggatag agcaatatat
    12961 cagcgagcac tacgaaacac gctacaacga agtgctgcat atcatggaat atcgcagaag
    13021 gcgtcccgac accgagaaac cggagccttt ccgcatcttg gatgagatga tggaaaacag
    13081 tatctggata gaaatcaacg agctgggata tccctgcact gtcaaaacaa tcgaaaatct
    13141 gatttactcc gatttcagcc agtcgtatca tcccattcgc gagtatttcg aattactgcc
    13201 cgaatgggac ggaaccgact atatccgtat cctggcggat agtgtccaga cgaatcatca
    13261 ggagttctgg gcggaatgcc tggaacgtta tctggtggcg atgtgtgcag cggctactca
    13321 ggagaatatt gtcaatcaca cggtacttct gctatgcagc gagatacaga acataggaaa
    13381 gactaccttt atcaataatc tcctgcctcc cgaactgcgt gcttatcttt ctaccggact
    13441 aatcaattcg aacaataaag atgatttagc caaaataacg caggccatgc tgatcaatct
    13501 cgacgagttt gaagggatga gcggtcggga actgaatgca ttcaaagatt tggtaacgcg
    13561 caaagtgatc agtttccgtc tgccttatgc acgccgttcg caaaacttcc ctcatacggc
    13621 ctcttttgca ggaacctgca actatcagga agtgcttcac gacacgacag gcaaccggcg
    13681 tttcctttgt tttcatcctt attccatcca atttattacc atcaattatg cgcagctcta
    13741 tgctcagatc aaatatctgc tgaataagcc ggggtaccaa tactggttca cgcaagcgga
    13801 caatgaacgg cttgaagaga ataacgaggc tttcatcttt cattcaccgg aagaggaaat
    13861 ggttcttacg catatccgca agccggaacg tttcgagaag gtttattatc tgactgtcag
    13921 tgagattgcg gaactaatac gtgagcgtac cggttatcag tattccatcg gatcaaaaat
    13981 acagttgggg aaagtgatgg ccaagcacca ttttgaatcc aaaaaaggaa ataacgggcg
    14041 ccgatatgcc gtatttatta tagatatcga gcaggtaaaa tcaaacaggc tgtatgaata
    14101 gaagcgggaa agccctgtga atatagataa atgcagagtc atcttgacag atactctgca
    14161 tttattgttt ttacaaaatc attgaaaatt cgattttaca gcctaacgca ttcattatac
    14221 gatagaaagt agatacttta ggctctgtct gaccactttc tactcttgaa atataagaac
    14281 ggtcagaacc gatacgccgg gctaattcag cctgagtgat tttagccttt tttcttgcgt
    14341 cctcgataat ctgccctgta taaaaggcgt aggccttttc ttctgcctct gcacgagaag
    14401 ctgttccttc cttaccaaaa cgctcatcta ttaatgcact gacattaaag aattcctcat
    14461 ttgtttttgc ttccataata ctcctttctt aatatctttg ctttatcaat ttctttcttt
    14521 ggtgtttttt cggttttctt ttgaaaaccg ttaaacagaa tcacaatacg cccttcgtcg
    14581 aaacaaaaga atattctata tatattgctt tggtactcga tacgaagttc ataaagtcct
    14641 tcttctatca accgcataaa tttcaaaggt attctgtctt gtgtctgcaa taacattagc
    14701 acatacaata tcttatcttg ggtgccagca tctaaatttt caaagaattc tttgaagtat
    14761 cctttatatg ctattatttc tcttttcata acgcaaatat aaggaatgtt gttcaactat
    14821 acaacacatt tcctcgtttt atattatttt tcatcatctt cacccccaaa agtgagagga
    14881 gtgagagagg aattgaaact ttttctattt tatttcttta tttctacttt ctatatttct
    14941 ctaaaaaaaa aatacgaatg ttagaaatcc tctctcactc ctctcacttt ttaccttttc
    15001 tttctccaaa aagacggcgg aaaatcggaa aaacacaacc gtctttttca atttcccacc
    15061 gcattttcaa atcagcccac caattgaagc agacttcagg aaatatttgt catctttgat
    15121 gtgcaaaaga tcaaaagaat cagatatgga caacttgatg cgtaaacttc ctattggaat
    15181 acaaaccttt gaagatatac gaaggaagaa tatcttattg taaagatcgg aatggaattt
    15241 agtgcagaaa gccgaaactt aaatcgttgg ttaatcgaag tgataggaaa gtaaaaatcg
    15301 agtaggagga aaacgaagta gaagttttcc tcctactttc gttttcc
//
