LOCUS       c00002_gnlPro..        16293 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ILJAEFDO_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 18:09:29
            Original ID  :: gnl|Prokka|ILJAEFDO_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16293
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16293
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2741:6293](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2742..6293
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16293
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16293
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(169..1383)
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="LNSFKMTKKALYIFNPEHDLALASGETNYMAPASARQMASELALL
                     PMWYAEEGSVVLAPSAYNLDYVKKIQELLGLSVDLMTEPELASERNLDIRPWGWDIAIR
                     KRLLDLGVEESELPSIEQLDKLRFCSHRSCAVGLLPQLQLGACFCGESFYLTFPEEWKS
                     FVESHDTCLLKAPLSGSGKGLNWCKGVYTPSISGWCSRIGKQQGGVIGEPLYNKVEDFA
                     MEFRSSSNGRFGFAGYSQFRTGGSGAYEGNLLISDAAIERNLLEYIPVEEIYKLRDRLE
                     QELSLRFGTIYNGYLGVDMMICRFPESPVYRIHPCVEINLRMNMGVVARHIYDHYIYPT
                     STGAFQISYYPTEGTAWRAHKEMEEAYPLEIEQGRIKSGYLSLVPAHKKSSYRAWVFIS
                     KSVFL"
     CDS             1531..2709
                     /locus_tag="ctg2_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             2742..6293
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_3"
                     /sec_met_domain="PFOR_II (E-value: 8e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 9.2e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 9.2e-31, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-11, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 3.2e-11, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 5.1e-08, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00025, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.6e-24, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNEILAADNASPEAKEVLKAWIENMYDADKTKE
                     LAPQVKAVIEEGLSHGCPICKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPTEAEELFKAAEENAK
                     WRYNSYKRLARENWGAE"
     CDS             complement(6446..7312)
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFFG
                     EVYGEARVGLVVPQYVTIHSINELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRLLVDSW
                     IPKSENK"
     CDS             complement(7333..8157)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.9; E-value: 6.9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_5"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-28, bitscore:
                     92.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMIHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSSRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             complement(8154..9380)
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTTGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(9680..10018)
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             10102..11397
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLLGA
                     LAFSSCEKNLYDESKQPEKEKKMTDLEVPADFDWKGSQNAKVKIASQSTATISVFLEEN
                     CNEEALMLRMDVDANTSKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNGTISIVVPA
                     NATALSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVAWYNFQIDG
                     FYWSHNQCYAEYLMIGFQIRAIGGIYDYNPYIRLAEVQYNELDLEETQMYLERNNPEEA
                     ENIKILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNSPVNVKSLQ
                     DSKMDFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHHAREEVNFL
                     EAYPDFEQWVTSGGQENQRWWNKPKTNKLIMN"
     CDS             complement(11537..14377)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63; E-value: 1e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_9"
                     /sec_met_domain="Peripla_BP_1 (E-value: 2.3e-19, bitscore:
                     63.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYTKWITVLFCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKVMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDQLIQLSH
                     QLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQRRMLLLVQRNVNILL
                     RLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAVARKKHIHFSFDYMPDTDYR
                     TLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIRFTVANTGSMISAEH
                     IRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQGTIFTVDLPVQTCET
                     VVSENSPAFSVSATSVTSTDATTSAVAGVPATPATSGYSGSSSLNDALTYEEEELEKSY
                     DSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAADGSEGIRKAMKYVPDLIISDVMMPG
                     MDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYISKPFSSQLLLARVR
                     NLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGDSNLNVEDLGKDMGL
                     SRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGYEVGFSSPSYFTKCY
                     REQFGESPTDLLKRKG"
ORIGIN
        1 acttaggtat aacaagcgaa gttgtcaact aaatccagta cagtacacac atggcatgtg
       61 attacttgtt tcatgcaatg aaactttttg tttctcggtg tggaaccaat ggtttcacta
      121 catgaaacta tcagtttcac accgagaaac cataacttcg atataatatc acaaaaacac
      181 gctttttgag ataaacaccc acgcccgata actactcttt ttatgagccg gcaccaatga
      241 caaatagcct gattttattc ttccttgttc tatttccaaa ggataagcct cctccatttc
      301 tttgtgtgct ctccaggctg ttccttccgt agggtaatag cttatttgaa aagctcctgt
      361 tgaagtagga tagatataat ggtcataaat atgacgcgct actactccca tattcatcct
      421 caagttgatt tccacgcaag gatgaatccg ataaacagga gattctggaa agcgacagat
      481 catcatatcc actcccaaat aaccattata aatggttccg aaacggaggg ataattcttg
      541 ttcaaggcgg tcgcgcaatt tataaatttc ttcgacaggg atatattcca aaagattccg
      601 ttcgatggct gcatctgaaa tcagcagatt accttcgtac gccccacttc cacccgtacg
      661 gaattgagag tatccggcaa agccaaatcg accattactc gaagaacgaa attccatagc
      721 aaaatcttcc accttattat atagaggttc gccaataaca cctccttgct gtttgccaat
      781 gcgtgagcac caaccggaaa tagaaggagt atatacacct ttgcaccagt tcagcccttt
      841 cccgctaccg gataaaggag ctttcagtaa acaagtatca tgtgattcta caaatgactt
      901 ccattcttcg ggaaacgtca ggtaaaaaga ctctccacaa aaacaggctc ccagttgtag
      961 ctgtggtaat aatcccacag cgcaggaacg atgggaacag aaacgcagtt tatccaattg
     1021 ctcaatagaa ggaagctcgc tttcttccac tcccaaatcc aacagtcgtt ttcttattgc
     1081 tatatcccag ccccaaggac gaatatccaa attccgctcc gaagcaagtt caggttctgt
     1141 catcaaatca accgaaagtc ctaataattc ctgtatcttc ttcacatagt cgagattata
     1201 agcggaagga gccaatacaa cacttccctc ttctgcatac cacatcggca acaaagccaa
     1261 ttcggatgcc atctgccggg cggaagccgg tgccatatag tttgtttcac cgctggctaa
     1321 cgccaaatca tgttccggat tgaatatata aagagccttt tttgtcattt taaacgaatt
     1381 caaaacttta ttctgcaaat atatacagga aatagtcagg aatggctaca ataaacagaa
     1441 agttctaatt aaactcacaa ttttgccatc tctactttgc aaatcctaaa aaaagcagta
     1501 tatttgccac ccgaaaaaca aagaactgaa atggaatcat tctatcgcac acacgcctac
     1561 ctcgttgagc acaccaatgc ccccgttcgc cgcgatctta tggacgagat cgactggagc
     1621 gaccgcctga ttggtatcaa agggacacgt ggcgtaggaa aaaccacttt ccttctccaa
     1681 tacgccaaag aaaaatttgg gaacgaccgc tcctgcctgt tcatcaacat gaacaacttc
     1741 tacttctctg gccacagcat tgtagacttt gctaacgaat ttcagaaacg tggcggaaaa
     1801 gtattgttga tcgaccaggt gttcaaacat ccggaatgga gcaaagagtt acgcatgtgt
     1861 tacgaccgtt ttcctaacct gaaaattgtc ttcaccggct cgtccgtgat gcgactgaaa
     1921 gaagaaaatc ttgaattacg tgatatcgcc aagagctata acctgcgcgg attttctttt
     1981 cgcgaatacc tgaacttaca gacaggcatg aaattcaggg catacagcct cgaagaaatt
     2041 cttagcactc acgaacagat tgccaaagga gtactctcta aagttcgtcc gctggattac
     2101 ttccaggatt acctgcatca tgggttctat ccgttcttcc tcgagaagcg taacttctcg
     2161 gagaatttgc tgaaaacgat gaacatgatg gtggaagtag atatacttct catcaaacaa
     2221 attgaactga aatatctttc aaagataaaa aaattactat atttgctcgc tgtcgacggg
     2281 ccgaaagctc caaatgtgag ccaactggca agcgacatac agacatctcg cgccacggtg
     2341 atgaactata tcaagtatct ggcagatgcg cgactcatta atctggttta tccgaaaggg
     2401 gaagaattcc ctaaaaaacc ttcgaagata atgatgcaca actccaacct gatgtattcc
     2461 atctacccgg tgaaagtgga ggagcaggat gtgctcgaca ctttctttgt gaattcttta
     2521 tggaaagacc ataaggtaca taaaggagat aaaaacgtct cttttatggt ggacgaagta
     2581 atgccgttca aaatttgcca ggaaggagca aagatcaaga acaatccgaa tgtgacgtac
     2641 gcgttgcata aggctgaaat aggtcggggc aaccagatac ctctctggat gttcggcttt
     2701 ttatattaaa agatttattt acttaaatat ttaatttagt tatgactaaa cagaagaaat
     2761 tcatcacttg tgatggtaac caggctgcag cgcatatctc gtatatgttc tctgaagtag
     2821 ctgctatcta ccccatcact ccttcttcga ctatggctga gtacgtagac gaatgggctg
     2881 ccgcaggacg taagaacatc ttcggcgaaa cagtattggt acaggaaatg caatctgaag
     2941 gtggtgctgc cggtgcagtt cacggttctc ttcaggctgg tgcgttgact actacttaca
     3001 ctgcttctca gggtcttctc ctgatgatcc ctaacatgta caaaattgcc ggtgagttct
     3061 tgccttgcgt attccatgta tctgctcgta cattggcttc tcacgcattg tgtatcttcg
     3121 gtgaccacca agacgtaatg tcagctcgtc agactggctt tgcgatgttg gctgaaggct
     3181 ctgtacagga agttatggat ttggctggtg ttgctcactt ggctactatc aaatctcgtg
     3241 ttccgttcat gaacttcttc gatggtttcc gtacatctca cgaaatccag aagattgaaa
     3301 tgttggaaaa tgatgatctt gctccgctga ttgatcagga agctttggct gaattccgtg
     3361 cccgcgcact gaatccgatg aatccggttg ctcgtggtat ggctgaaaat cctgaccatt
     3421 tcttccaaca tcgtgaatca tgcaacaact actatgaagc agttcctgct atcgtagaag
     3481 aatacatgaa tgaaatttct aagattacag gtcgtaaata cggtttgttc gattattatg
     3541 gtgcagaaga tgcagaacgc gtaattatcg ctatgggttc tgtaacagaa gctgcccgcg
     3601 aagctatcga ccacttggta gcaaatggcg aaaaagtggg tatggttgcc gtacacctgt
     3661 atcgtccgtt ctctgctaaa cacttcctgg ctgctgtacc taagactgcc aagactatcg
     3721 cagttcttga ccgtactaaa gaaccgggcg ctaacggcga acctctttac cttgacgtta
     3781 aagactgctt ctacggcgca gaaaatgctc cggttatcgt tggcggtcgc tacggtttgg
     3841 gttcaaaaga tactactcct gctcaaattc tttcagtatt cgagaacttg gccatgccaa
     3901 tgccgaagaa tcacttcact atcggtatcg tagacgacgt tactttcact tctcttcctc
     3961 aaaaagaaga aatcgcttta ggcggtgaag gaatgttcga agctaaattc tacggtttgg
     4021 gtgctgacgg tacagtaggt gctaacaaga actctgtaaa gattatcggt gacaacactg
     4081 acaaacactg ccaggcttac ttctcttatg actctaagaa gtcaggtggt ttcacttgtt
     4141 ctcacttgcg tttcggtgat actccgatcc gttccactta tttggtaaat actccgaact
     4201 tcgttgcttg tcacgttcag gcttacctgc acatgtacga tgtaactcgt ggtttgcgta
     4261 agaacggttc tttcttgctg aacactatct gggaaggtga agaactggct aagaacctgc
     4321 ctaacaaggt taagaaatat tttgcacaga acaacatttc cgtatactat atcaacgcaa
     4381 cacagattgc attggaaatt ggtttgggta atcgtaccaa cactatcctt caatctgcat
     4441 tcttccgtat cacaggtgtt attcctgtag accaggctgt tgaacagatg aagaaattca
     4501 tcgttaagtc ttacggtaag aagggtgaag acgttgttaa caagaactat gctgccgttg
     4561 accgtggtgg tgaatacaag actttagctg ttgatcctgc ttgggctaac ctgccggatg
     4621 atgcaaaagc tgaaaacaac gatcctgcat tcatcaacga agtagttcgt ccgatcaatg
     4681 cacaagatgg tgacttgctg cctgtatctg cattcaaggg tatcgaagac ggtacttggt
     4741 atcaaggtac ttctaaatac gaaaaacgtg gtgtagccgc attcgttcct gaatggaatc
     4801 cagaaaactg tatccagtgt aacaagtgtg catacgtttg tcctcacgct tctatccgtc
     4861 cgttcgtact cgatgctgaa gagcagaagg gtgctaagtt cgaacaattg aaagcagtag
     4921 gtaaagtatt cgacggtatg acattccgta tccaggttga cgttctcgac tgtctgggtt
     4981 gcggtaactg tgctgacatc tgtccgggta atccgaagaa gggtggcaaa gcattgacaa
     5041 tgaaacacct cgaaagccaa ttggctgaag ctgacaactg gacttactgt gctgaaaacg
     5101 tgaagactaa acaacatctt gttgatatca agtctaacgt gaagaactca cagttcgcta
     5161 ctccgttgtt tgagttctct ggtgcttgct ctggttgtgg tgaaactccg tatgtgaaat
     5221 tgatttctca attgttcggt gaccgtgaaa tggttgctaa cgctaccgga tgttcttcta
     5281 tctactctgg ttcagttcct tctactccgt atactacgaa cgaaaacggt cacggtcctg
     5341 cttgggctaa ctcactgttc gaagacttct gtgaattcgg tttgggtatg gaattggcta
     5401 acgaaaagat gcgtgctcgt atcgtgaagt tattcaacga aatccttgct gccgacaacg
     5461 cttcacctga agcaaaagaa gtgctgaaag catggattga aaacatgtac gatgctgaca
     5521 agactaaaga attggctccc caagtgaaag cagtgattga agaaggtctt tctcacggat
     5581 gtcctatttg caaagaactg aaaggactga ctcaatatct tgtaaaacgc agccaatgga
     5641 tcattggtgg tgacggtgct tcttacgata tcggttatgg tggtcttgac catgtaatcg
     5701 cttccggtaa ggacgttaac atcctcgttc tggatactga agtttactct aacacaggtg
     5761 gtcagtcttc taaggctact ccggtaggtg ctatcgctaa gttcgctgct gctggtaagc
     5821 gcgtacgtaa gaaagacctc ggtctgatgg ctactactta cggttatgta tatgttgcac
     5881 agatcgctat gggtgctgac caagctcaaa ctctgaaagc tatccgtgaa gctgaagcat
     5941 atccgggacc atctttgatt atcgcttacg ctccatgtat caaccacggt ctgaaagcag
     6001 gtatgggtaa gagccaggaa gaagaagaaa aagctgttaa gtgcggttac tggcacttgt
     6061 ggcgttacaa cccagctttg gaagaagaag gcaagaaccc attccaattg gatagcaaag
     6121 aaccgaactg ggaagatttc caaggtttct tgaagggtga agttcgttac gcttctgtaa
     6181 tgaaacaata tcctactgaa gctgaagaac tgtttaaagc tgctgaagaa aacgctaaat
     6241 ggcgttacaa cagctacaaa cgtttggcta gagaaaactg gggtgctgaa taatagtaat
     6301 accctataaa tataaagcgg taatcttatc aaagattacc gcttttttat tgtatgaact
     6361 ctgtccaaca taaacagtac tccctttttc ccactagagt tcatgtctat tttatattta
     6421 aaattaagaa taacaatgct ccaatctatt tattctctga cttcggaatc caactatcca
     6481 ccaacagccg atgctcatcc ctccatttac gggctatttc ttcttcatcc atcctggcat
     6541 ccttcatagc tgtcataaaa gagctaagtt cttctgtcgt tagtttgatg ttgccaaaga
     6601 attcggcagc aaacggatct ttctcactga atcctttcca tgcaatagca tgtatttctt
     6661 ccaagtctcc atatactttc ttcggatcat ccaagaattt caagtcaaac tggtcgaaca
     6721 tccaatgcgg tgtccacccc gtaatgacaa tccattctcc tttgtccatc gcttttttca
     6781 aagaagccag catggtggaa ctacttgaag tcatgagggt atacccatca agtccgtaag
     6841 cagcaatggc cttatcggtc gtcttcatta tccctgctcc cgcatcaatt cctactattt
     6901 cagaggaaaa acggtcttta ttagcttcca gctcattaat agagtggatc gtaacatatt
     6961 gaggaacaac cagtccgacg cgagcttctc cgtatacctc cccaaaaaat tcgatgctgt
     7021 ctccatactg atccatataa tctttcatcg ttattggtaa ccatgcatcc agaaacacat
     7081 ctgatttctt tcctgacata gatacaaaaa taggggcaag atcagcattt tgcaattcaa
     7141 cctcatatcc atgctcttcc aataccacct tagccaaatg actcatggca ataccttcca
     7201 gccaattggc ataggctatt tttactttct ttttctctaa gtctgaatta gtacaggaag
     7261 ctagcaaaag catagctgac aatactattc ctactatttt atatattctc atacgtattt
     7321 tatcctttcc gtttagttct tattttttcg tcctgccatt ccttgcgtga tacggtctaa
     7381 gatgatagct aaaataacaa ctgctatacc accttcaaac ccaagtccga ttttcatttg
     7441 ggtaatacct ttcaatacaa tttctcccag accaccggca gcaatcatgg cagcaattac
     7501 aaccatagaa agcgacatca ttattgtctg gttgacacca gtcagaatgg tgggcaacgc
     7561 caaaggaagc tgcactttat acaataactg ccaacgggta gctccgaacg aacgggaagc
     7621 ttccactaca tttttaggaa cttgccggat tcccaatccg gtaaggcgga ccacaggagg
     7681 catagcaaag ataatggtgg caaacactcc tggcactgct cccaatccga aaaacaaaac
     7741 agcaggaatc agataaacaa aagcaggcat cgtctgcatc aagtcgagaa caggacggag
     7801 tattttctct gcacgcgaac tgtttgccgt ccatactcct aaaggtacac caacaatcag
     7861 ggccagacag gtagatgaaa aaacgagagc tagagtttgc atggtagcct cccagaatcc
     7921 cattccatag atcagtaata atcccaatgc ggtgaaaatt gccgtaccgc gtcctgcttt
     7981 catccatgcg agtgcagcaa gtaccaaaat ggttatataa aaaggtattc cgaaaagtat
     8041 gtgttggaat cctataataa aactaccgat gcccgcattc acggcatcaa agaaagtgga
     8101 aaaatgtatc atcatccaat tgatggccat ctctatatat tgtcctatat ttatcataaa
     8161 tctattgcgt tttgaattat ttcgtttatt tcttctttat ctttcccggt cacttcgatg
     8221 attaaggatg aaagcgggat tgttcctaaa aactcgcgcg tctcatcaat cacccatacc
     8281 ggcgaattgc tctttgtcat tagaggaagt atatcctcca acaccgtatc ctccaacaca
     8341 gaatgtactt ctgtacgcac aatcgtttca atggattttt cctgtttgct acgtaactta
     8401 agcaagtcgt tcagacgtac ttctccgacc agtttatcat cggcgtctat gacaggtaat
     8461 acggtgatat tcttcgcacg catcttacga atcaatactt cgggaccttc tttcttcaga
     8521 cgggccacca acggtttgtc aatcattaaa gaagaggcgg taataatttt gctcctatcc
     8581 acgttttcaa caaaacgggc tacataatcg ttagccggtt cagtcaggat ttcctccgaa
     8641 gtacctacct gcaccacttc tccgtctttc atgatggcaa tacggtcacc tagcttaatt
     8701 gcttcactca agtcgtgggt aataaaaaca atcgtctttt tcatctttga ttgcaaggcc
     8761 agtagttcat cctgcatctg tacgcgaatc agaggatcga gagcagagaa agcctcatcc
     8821 attaaaagca cttcaggatt attagccaga gcgcgagcca gtccgacacg ctgttgcatt
     8881 ccaccggaaa gctcgcctac catctgattt tcatatcctt tcaatccgac aagcttcatg
     8941 ctttccatcg ctttcttctc acgttcctct ttcttcactc cctgaagttc gaggccgaac
     9001 gcgatattgc tcaatacgga acggtgaggt aacagaccga aattctggaa aaccatcgcc
     9061 agctctttcc gacgaacctg caataattct ttttcggaaa ttttagatat atctactccg
     9121 tttacaagca cttgcccggt agtaggacgt atcagacgat tgatacaacg cagtaatgtc
     9181 gattttccac ttcccgagag tcccattatc acgaaaaact ctccttcatt aattgaaaga
     9241 ttggcatctt tcactcctac cgtacaaccg gtatctttca gaatttcctc tttactctta
     9301 tcttttttca acatcttgag ggctttctgc ttctcgttac caaagataag gtacaaatcc
     9361 tttatttcta ttttactcat ataatatatt ggtttagatt ataatatttg ttttgttttc
     9421 aactgccgca ttccttattc tcacttacga taaacaagtt gaatgttcgc atggttcagt
     9481 catgtcacat gataacatga cggtccgacg ttttttaaat ggttaaaaaa aaacagacag
     9541 agtagtttaa aaggaataga atttgataag attatcctct taatgaacag tagaaaacag
     9601 tattttcata aataaataac agtctgttct tgcatattgt tggcacaaag gtaaggaaaa
     9661 tagattaaat atgcaaattt cattcaggta cggagtaatt ccaaagatgc tttttcaagt
     9721 ctacgcatcc attttgtttg aaagagatcc cttcttccaa caagagttgt ttctgctctg
     9781 tccaacccgg aacaagccgt cccgacgcat tgacaacccg atgacaaggc gcagataaat
     9841 catccggaat ctgtttcaaa gcacgcccca ccatacggga acattgagac attcccaata
     9901 atgcggcaat tcccccatag gtagaaactt tacctaccgg aatttctcgg acaacctgat
     9961 acacctcttg acaaaaggat gcggaaaggc tcgccttatc tactttataa tctttcatca
    10021 ctcaaacatt actttatttc agttccaaaa ctagataaaa agaaaagaat ttgcaaataa
    10081 taaaagcatt tcaaataaaa tatgcaactt tatttgcttt atttacaaat aatcccgacc
    10141 tttgtaccca ttaaaagcaa ccctattatt aacaaaacaa gcactgctgt tatgaaaaag
    10201 aaaactatcc tgttcgcttc ttgtttattg ggagcactgg ctttcagctc ctgtgagaag
    10261 aacctttatg atgaaagtaa acaacccgag aaagaaaaga agatgactga cttggaagta
    10321 cctgccgatt tcgactggaa aggttctcaa aatgccaaag tgaaaattgc cagtcaatca
    10381 actgctacta tttctgtatt tctagaagaa aattgcaatg aagaggcttt gatgcttcga
    10441 atggatgtcg atgccaacac atcaaaattg gaactcccaa ttgaaattcc tgcatatata
    10501 aaaaatgtgt atgtaaaata tggtaatggc tctgaaatac aaactgttcc tgttgaaagt
    10561 aatggtacta tttctatagt agtacctgct aacgctacgg cattatccag agttaccaca
    10621 agagctaata aagaagttga aacgaacaac atcttcaatt atccgggata tggcaacgga
    10681 actattatgt tcgaagatat gtatccagct ttaggcgatt atgattttaa tgattttgtt
    10741 gcatggtata atttccaaat tgacggtttt tattggagtc acaatcaatg ttatgcagaa
    10801 tacttaatga taggattcca aatcagagct ataggaggta tatatgacta caatccttat
    10861 atccgcttgg cagaagtaca atataatgaa cttgatttag aagaaactca aatgtatctt
    10921 gagcgtaaca atcctgaaga ggctgaaaat atcaaaatcc taaaaggccc aaaaggggaa
    10981 ttgattattt cactaaagaa accggccatt cctaacggat acaagtatta taatacggag
    11041 gtaaatgaaa aaacaaagcc taaaaaaatg atggccattt acttggtgtt caactcacct
    11101 gttaacgtta aaagcctaca agacagtaaa atggactttt atattgcaaa aactaataaa
    11161 ggacaagaaa tccacttaaa aggttatagc ccggtttatt ataacagcaa cgaaagttat
    11221 gtaaatgaag acaactttat atggggatta aaagtacctg catctttaca tcatgccaga
    11281 gaagaagtaa acttcttgga agcatatcca gactttgaac aatgggtaac atcgggaggt
    11341 caagagaacc aaagatggtg gaataagcca aaaacgaata agttgattat gaattaataa
    11401 atatacagta aatcatatac tgaattaaat aagaggtaag gtatgtcaat agatttcctt
    11461 acctcttatt tttatcatat gaattctaga agtataaaca gataaatgct caccaccaaa
    11521 ttttgcagat tctatcctat cctttcctct tcaacaaatc tgtcggactc tctccaaact
    11581 gttctctata acatttagta aaataagaag gagaactaaa accaacttca taacctatct
    11641 ctgccactgt catatccgac gaagcaagca gggaagcagc tttcttcaaa cgagctatac
    11701 gaagcagttc attcggggaa taattagtta gggatttgat tttgcgatag agttgcacac
    11761 ggcttaatcc catatcttta cccaagtctt ccacattcaa atttgaatct cccatctttg
    11821 cctcaatcaa agctttgaat ttttccacaa agtctttatc catatcacag acatcctctt
    11881 tcgccaacgt ttgtccgtca ccaaaaaact gtttcaggcg gcggtgtgaa tctatcagat
    11941 tacgaacgcg tgccaatagt aattgcgaac tgaaaggctt ggagatataa gaatctgcac
    12001 caccatcata cccttgaatt cgttgttcat ccaaagaaca agctgtcaat aggataacag
    12061 gaatatgaca ggtttgtaat tcgcttttca agcgacgaca acattcaatt ccatccattc
    12121 cgggcatcat tacatcggag ataatcaagt ccgggacata tttcatagct ttacgaatac
    12181 cttccgagcc gtctgcagct tctataacag tataatcagt atgaagcaat ccatgcacat
    12241 ataagcgaat atcagcgtta tcatcaataa tcagaacgca aggtttggaa gagtcgtaac
    12301 ttttttccaa ttcctcttct tcgtaagtta aagcatcatt caagctcgaa gaaccggaat
    12361 aaccggaagt tgcaggagtt gccggaaccc cagcaacggc agaggttgta gcatcggtgg
    12421 aggttacaga agtagcagac acagagaatg ccggagagtt ttcagaaaca acagtctcgc
    12481 aagtctgcac aggcaaatca acggtaaaga tagttccttg cttttcatca ctttccaccg
    12541 tgatggtacc tttatgcaat tccacaaaag cctttaccaa tgccagtcca atacccgaac
    12601 cggcatggtg catatctatc ttatagaaac ggtcgaaaat attccggata tgctccgcag
    12661 aaatcattga accggtattg gcaacggtaa agcgaatcca gcaatgatcg tctttagtca
    12721 gggaagacaa gcgtacagtt acttttccgt tttccggagt aaatttgaaa gcgttggaaa
    12781 ggaggttgaa atagatgcgt tccaactttt ctacatctgc caatgtgcgg taatccgtat
    12841 ccggcatata atcgaatgag aaatgaatat gcttcttccg ggctactgcc atgaaagatt
    12901 cgttccatcc ttcaaaagaa gaaagaatgt ctaacgaaat aggagtatat tccatttttc
    12961 cattctcgta tttacgaaaa tccagaatct gattgacaag acgcaaaagg atattcacgt
    13021 ttcgctgaac taacaataac attcggcgct gatcttcact caaagacgaa tcagccagta
    13081 aatgctctac cgggtcggca actaatgtca gtggagtacg aaaatcgtga gatatatttg
    13141 tgaagaaaac cagcttggca tgagtcgctt cttccagttg atgagaaagc tggataagct
    13201 gatcccgttg ctcttcgagt ttatcgcgct gttgctctac ttgtttcttc tgttcggaca
    13261 actctttatt caggcgattc ttggaacgga gggatttata gactaccaac aacaatcccg
    13321 ctactaataa aagaataacc aagccgccat acatcacgac ctgctgcgta gctacacgcg
    13381 acagataccc accgatacgt ccgttcaatg tttcaatctt ctgatccagt tccgagatat
    13441 gggtagtctg aagttgcata acgtgcgcgt tcgtgcggtc tacaacggca gtattcatga
    13501 ccgtttcgcg aggataagac ttcttctcaa gaatattcat ggccagttgc atcactttgt
    13561 ccccattagt cggataaata aaagttgcat ccagcacatt gtcaagcacc aattcaagcc
    13621 cgtttccttt gccgggcagg gcatcaatgc caacaaaaat cattaccttt tcacgtccgg
    13681 ctttcttcgc agcttgatag gctcccggag cgatacggtc gttatgtgca tataccgcat
    13741 caatcttcgg atgacggcga agcatactat ccatttccac ttctgccggt tcacgttccc
    13801 aggcagcatc cgctttatca atcagtttga tatccggata attgctgata gcagccataa
    13861 atccctgatg gcgttccatg gcaggggtgg aaccacccag tccggtaagc tccactacat
    13921 tccctttccc tttcagactt gatgcgatat aatttcctac cgcacgacct atttcataat
    13981 tatcggcacc gatataggca gtatatttat cagaaagtat cttccggtct acaagaatga
    14041 caggtattcc tttctgatag gcctcctcca caattggagt catgggagcc gcttcattgg
    14101 cggaaattat cagtaaatca actcctttat ctataaaata atgaacatct tccgcctgct
    14161 tacggttatc atccgccgcc gagcggattt caaccgacac tccatcataa aacatcgctt
    14221 cgcgaagaat ctcatcattc atcttgtgcc tccaagagtc atcgctacat tgggccaccc
    14281 caatacggaa acgaggcgca tcctgccgac aggccgccaa gcccaaaaga caaaacaaga
    14341 ctgttatcca cttcgtatat ttcatcgctt caatcattcc ctttctttcg tatatctttt
    14401 gtatttcttt ctgtaatcca aatttctccc cccgcattat ttgcattcac caccgggaaa
    14461 tacatcagtt ccactttcac agggttcagc gtatattttc cagtaaagcg tggaagcaaa
    14521 ggaaccgtaa actgataagt acctaccggt aatttttcgc taaagataac agttttctct
    14581 ttaaaatact cacgatatat ttcagaacgg gagaaattaa caggttttga ggcataacta
    14641 caacctgccg gaacaggaac ttcgagcatc acatattgcg caccctcctg tttcacctgc
    14701 aaggtaactg tcaatgtaac aggtacaccc gccaccaaag agtctttttc caaagtcacc
    14761 tccaccttga aagcatcact ctgacgagca ttcatcacac gcttcattga atagacacta
    14821 tacaataaag gctcttttcc cgtttttgaa ataagcagac tgtcgcttgc tgtcagccgg
    14881 gcatgataag gaaattccgt aattcgttga tgatccttac cgctcacaga caccgacgtt
    14941 cctgacatcc ctccggaacc tgccagcaaa tcggtcagaa cagttgccac agccgaagaa
    15001 gcctgatacg tattccatcc gcgctcctta gtccgcaaaa tatacaattg catattttct
    15061 ttcaacttac acagggaagg gtcattttta ataatccggt aggctatcaa tgtatttatc
    15121 atctgatttc cctcccaata ataagtacgc cgtccgtcgt cacagtaaac accttccagc
    15181 atatcctttt tcagataagg acgtacgcta tcacccacat tcaccgaatc cacctgttgc
    15241 ttgatttccc agagaagcag cttctctttc aagtatgaaa gaggacgata atacttgttt
    15301 ctatttgcca acgagtcttc tttctgttcc aattgccgga cgaaaggttc caataatctg
    15361 actgccgaag aataatccgc ctctactttc cactcatgca gagcatgaag tatttctata
    15421 tcttccagtt tcattcctcg ataaggacgc gtatgagcat actccacttt caaaccattc
    15481 agattcaact ccacaggata acctgcatct tgcgccatct tcaaagcccg cagaatatgc
    15541 gcagacatcc agaaagaagt attttcagag ttcccccacc acgaccataa ctgatgtttg
    15601 ttctgatgat tcgtcagtcg atggatgata ggtcgaattg ctttatctac tttcaccttt
    15661 tcacccttac tctgcatata ctgttggtaa gccaacaaac cgattaactt ggatgccagc
    15721 tgctcattgc acaaatattt gtatcctgtc aagtaattca ctgattcttt atagatgtcc
    15781 aactgattgt cagtgatact caccatcact tcttcatcct cgccggattg cactttaacc
    15841 gtctttgcat cggacagaat acccaatgtg ccctccgcca attcagttcc ctgtgccagt
    15901 atcggaatcg tatattcctc tccatcctga tagccatcgt cgcgagtgaa aagatagctg
    15961 atggtcacgc tatcggcatg aactgcctgc atcggcactg tttcatgaaa tccctccatg
    16021 aaactcactt cctgccgttt caacgtatcc gttccgacgc agaactgtgt ctttccggct
    16081 atgtgctgcc catccagata attgcggata gtcccgacca ccgtactctg atccccctcc
    16141 accaagaagc ggggagtttt caactccgcc atcaacggtt tgtaagagcg gacgaaacgt
    16201 cggaaagtac ccgtctgcaa acgacggttc atgccataaa cgacagtttc ccatttcgtc
    16261 acattatcgg ggaaagttgt ttcaaactgt acc
//
