LOCUS       gnlProkkaNLOPLDIL_545  11675 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NLOPLDIL_545.
ACCESSION   gnlProkkaNLOPLDIL_545
VERSION     gnlProkkaNLOPLDIL_545
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:24:51
            Original ID  :: gnl|Prokka|NLOPLDIL_545
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11675
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11675
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1321:1675]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1322..1675
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..11675
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11675
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..194
                     /locus_tag="ctg537_1"
                     /transl_table=11
                     /translation="MGIHPRNFNITPNGKYLLAACRDSNVIQVYKRNEVTGLLEDTHQD
                     IVVDMPVCVQFVSSVNNL"
     CDS             265..1314
                     /locus_tag="ctg537_2"
                     /transl_table=11
                     /translation="MKKNILMLSALFLSITAMAQTDVTTGVMRGKDYGVTYMLPKTEIE
                     IVLQATKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYFVKM
                     KDKTVAPLMELTEDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSNSSA
                     KMAELVAKEIYSIRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGKIKK
                     EPKTFTIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEEGKK
                     KVDGVAYNLPGKAQVTLMYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFDTAT
                     GGLIKVDRE"
     CDS             complement(1322..1675)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg537_3"
                     /sec_met_domain="PqqD_RRE (E-value: 2e-10, bitscore: 30.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.5e-17, bitscore: 53.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRR
                     FLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQ
                     LRKDGFIQLTIRN"
     CDS             complement(1695..3086)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 100.5; E-value: 1.3e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg537_4"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFIFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTSIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             complement(3240..3629)
                     /locus_tag="ctg537_5"
                     /transl_table=11
                     /translation="MYLLLVILMLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEA
                     PQSEAPAATTPAEAPAPAAEAPAAE"
     CDS             complement(3634..4407)
                     /locus_tag="ctg537_6"
                     /transl_table=11
                     /translation="MTPTHLQQWIQHPETLNRDTLYELRTLVARYPYFQSLRLLYLKNL
                     YLLHDINFGAELRKAVLYVADRRVLFYFIEGDRYTLKSRKVSSLFSGDLEKEPSVDRTL
                     SLIDAFLATVPEEHSQHTELDYAVDYTAYLMQEEPGVDAEDESEVPKLRGHELIDDFIQ
                     KSESSDASDTRREFLVEKEEETEEEEEPSVSPVTEELDDSCFTETLAKIYIKQHRYDKA
                     LEIIKKLSLNYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             complement(4412..4936)
                     /locus_tag="ctg537_7"
                     /transl_table=11
                     /translation="MDWIKKAAFASLLVSLLFLVNSCSMKLGLAPISSIDYTKVKTISI
                     ADFQNRAEYVYAPLATEFNQKMKDMFIQQTRLQLVNSGGDLEIDGEITGYNQYNESVDA
                     SGYSSKVKVTLTVNVRYTNNTNHEEDFEQQFSAFQTYDSSKLLTEVQDQLITLMVKDIA
                     EQIFNATVANW"
     CDS             complement(4923..5591)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 159.7; E-value:
                     1.8e-48)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg537_8"
                     /transl_table=11
                     /translation="MTQAIADGRFREDLYYRLNTVPIQVPPLRERGEDVVLLFRKFASD
                     FAEKYRMPAIQLTEDGKQVLLGYSWPGNVRQLKNITEQISIIETNREINASILKGYLPE
                     QNNMQRLPALFGVKEDKSFGSEREILYQVLFDMRQDVTDLKKLVHEIMAERGTVANPAV
                     ATFQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAQDLNISERTLYRKIKEYGLD
                     "
     CDS             complement(5588..6064)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 204.7; E-value:
                     4.2e-62)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg537_9"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNNEALMRAIDIAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EANGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVEKTDVRIVAATNVT"
     CDS             complement(6066..7163)
                     /locus_tag="ctg537_10"
                     /transl_table=11
                     /translation="MEDNKIRVGITQGDINGVGYEVILKTFADPVMLELCTPIIYGSPK
                     VAAYHRKSLDLPTNFSIVNSASEAVPNRLSVVNCTDDEVKVEFSKPDVEAGKAALGALE
                     KAIEEYKEGMIDVIVTAPINKHTIQSEEFAFPGHTEYIEQKLGDGEKALMILMKDDFRV
                     ALVTGHIPVKEIAGSITKELIQEKLKIFNRSLKQDFAISAPRIAVLSLNPHAGDGGLLG
                     TEEQEIIIPAINEMAAKGMLCYGPYPADGFMGSDNFTHFDGILAMYHDQGLAPFKALAM
                     DEGVNYTAGLPVIRTSPAHGTAYDIAGKGIASEDSFRQAIYVAIDVFRNRQREKEAHAN
                     PLRKQYYEKRDDSDKLKLDSVEEDL"
     CDS             complement(7169..8224)
                     /locus_tag="ctg537_11"
                     /transl_table=11
                     /translation="MRKHLFYLSMVLVLTLFSACGGGKKGVFTPTSSGRAYEVLVVVEP
                     GLWERPAGRALFDVLDSDVPGLPQSERSFRIMYTAPSNYDATLKLIRNIIIVDVNKDLY
                     TQPKFKYARNVYAAPQSILTIQAPDEASFEKFVEENRQVIIDFFTHAEMNRQISVLKDK
                     HSDYIATKVKSQFDCDVWVPGELTSTKEGENFFWAGTNAATGDQNFVIYSYPYTDKDTF
                     TKEYFVHKRDSVMKANIPGAREGMYMSTDSLMTDVRPISVQGDYALEARGLWRIKGDFM
                     GGPFVSHVRLDKANQRIIVSEIFIYSPDKMKRNLVRQMEASLYTLKLPGSKQEGAEIPV
                     GVTSKDTTNNK"
     CDS             complement(8294..9334)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg537_12"
                     /sec_met_domain="PF04055 (E-value: 3.7e-17, bitscore: 53.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKRPLLGLTLSELQNVVKNLGMPGFSAKQIASWLYDKKVTSIDE
                     MSNLSLKHRELLKEIYEVGAEAPVDAMRSVDGTVKYLYRAGEGHFVEAVYIPDEDRATL
                     CVSSQVGCKMNCKFCMTGKQGFTANLTSNQIINQINSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALEIMTASYGYAWSPKRVTLSSVGLKKGLQRFIEESDCHLAISLHSPIPLQRRE
                     LMPAEKAFSITEIVELLRNYDFSKQRRLSFEYIVFKGVNDSLPYAKELLKLLRGLDCRI
                     NLIRFHAIPGVNLEGADMETMTAFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEE
                     NKEELI"
     CDS             complement(9486..11624)
                     /locus_tag="ctg537_13"
                     /transl_table=11
                     /translation="MATLQNIRSKGPLLVIVIGLALFAFIAGDAWKVLQPHQSQDVGEV
                     NGESISAQDFQALVEEYTEVIKFSSGNSALSDEQTNQIKDEVWRTYVNNKLIEKEAKKL
                     GLVVSKAEIQAIINAGVHPMLQQTPFRNPQTGAFDKDMLKKFLVDYSKMNKAQMPSQYA
                     EYYESMYKFWSFLEKSLIQARLQEKYQALITKSLFSNPVEAQDAFDARVEQSDLLLAAV
                     PYSSIVDSTIVIKDSDLKAAYDKKKEQFKQYVETRNIKFIDVQVTASAEDRAALQKEME
                     EYTEQLTANPSDYTTFIRSTGSEAPYTDLFYTTKSLPADVTARLDSVAVGGVFGPYYNV
                     SDNTLNSFKKLATAAMPDSIEFRQIQVVAEDAEKTKTLADSIYNAIKGGASFAEIAKKY
                     GQTGEPTWISSANYEGAQIDGDNLKYITAVTTLGQNELTNLALGQANVILQVTNKKAVK
                     DKYKVAVIKRPVEFSKETYSKAYNEFSQFIAANNTLEKMIANAEDAGYKLLDRADLYSS
                     EHGIGGIRGTKDALKWAFEAKAGEVSGLYECGESDRMLVVGVASIVPEGYRPLALVKDQ
                     LRAEILRDKKAEKIMADMKAANATSFEQYKNMANAVSDSVKHVTFSAPAYIPALRSSEP
                     LVGAYASIAEVNKLSAPIKGNGGVFVLQPYAKEKLNETFNKETEEANLANMHARMASQF
                     ISDLYLKANVKDQRYLFF"
ORIGIN
        1 ccaccggcat ccatccccgc aacttcaaca tcacgcccaa cggtaaatac ttgcttgccg
       61 cctgccgcga cagcaatgtc attcaggtat acaaacgaaa cgaagttacc ggactcttgg
      121 aagatactca tcaggacatt gtagtcgaca tgccggtttg cgtacagttc gtcagctctg
      181 ttaataattt ataaagcaat atttagcaaa gataacttca ttaactttgt cccttagcta
      241 aatcagtcta aacgaatgta cattatgaag aagaatatat tgatgctctc agctctgttc
      301 ttgtctatca ctgccatggc gcaaacagac gtaaccaccg gtgtgatgcg tggcaaagac
      361 tacggagtga cttatatgtt gcccaaaaca gaaatagaaa tcgtattgca agccaccaag
      421 catacctaca ctcccggaga attttgcaga tatgccgacc gctatctgcg tctcaacaac
      481 gtgtctgccg aacccgagga gttctggaca ctggataaga tagaaacccg catagccggt
      541 gtaccggata aggacaacgt ctatttcgtg aagatgaaag acaagaccgt agcacccctt
      601 atggagctta ccgaagacgg aattgtccgc tccatcaaca ttccgttcag cggtaagcct
      661 gctgccaaga cgcccgaagc caaagccacc gaaagcagca ttgacccacg cagttttctg
      721 acggaagaaa tactgatgtc caactccagt gccaagatgg ccgagctggt ggccaaggaa
      781 atatacagca tccgcgaaag caagaatgcc ctcctgcgcg gcgaagcaga caatatgccc
      841 aaggacggcg cccaactcaa gctgatgctt gacaatctga accagcagga aacggctatg
      901 acggaaatgt tctcgggcaa aataaagaaa gaacccaaga cattcaccat ccggctgacg
      961 cctaaagaga tgaaagatga ggtggctttc cgtttttccc gaaagctggg agtggtggcc
     1021 aataatgacc ttgccggtga accgtattat atcagcgtca ccgacctcaa aagtcccgat
     1081 gtatctgcca ccgaggaagg caaaaagaaa gtggacggtg tagcctataa ccttccgggc
     1141 aaggcacaag tgacattgat gtataacaat aagaaattgt ttgacgacca acttcccatt
     1201 acccaattcg gcaccgtaga atacctcgca ccggtactgt tcaacaagaa ttctaccatc
     1261 aaagtgctgt ttgatacggc aacgggagga ttgataaaag tggataggga ataaaggaat
     1321 tctaattccg gattgtcaac tggataaatc catccttacg caactgcatt acgtaggcgg
     1381 tgacccgggg aatataattc tcttcctccc caaagtgcct ggcaagtaga gagatgattt
     1441 cgcgcacggt acgatgtcca tctatcagat tccagacagc tgtaccgtgt tcttccagcc
     1501 tcacatggat gtcaggagac atccccttcg gcaataaaaa acgacgcatc cattcgtatt
     1561 taaaccgtgg gtaggcgagt acggcgcact caccttccca ttcggttgtt atatgtccac
     1621 agcggaccgg aacagcgtcc aacagactta cttttccttc gggtatttcc atcatacggt
     1681 atccgctttt cctattattt ctgaatatta ggctcttcca gcttataacc atacttcttg
     1741 tctgccttct tcagcagtag agccactata agggacaagc aggcaatact ggtaaaaatg
     1801 cacataggca ccgtatagtc atacatattc gttccatctg gtttcttgcc ggatatacaa
     1861 taggcatcaa gcacccaccc tatcaatgta ggaatacccc aaagaccgat attctggata
     1921 aagaaaatca atgcgtatgc cgtacccaac tggcttaccg ggaatatctt ggccacagcc
     1981 ggccacatgg cagaaggtac cagcgagaaa gcgataccca aaattatcat cagcacaata
     2041 gctaccagcc aatagtttat atcgggaata gcataaatga aatgcacaca tatcagcatg
     2101 gccgagccca gcagcatgat agatgcggac ttacctcgct tgtcaatgaa accaccaaag
     2161 accggagtca gaatcagcgc tcccaatgcc ggaagtccgg caaatgtacc ggccacattc
     2221 tcattgatac cgtatttgat aatcatcaac tcggaagcaa acttctggaa tgggaataca
     2281 caagagtaga acaatacaca cagcaatgct atcagccaga aaccgggatt gaccagaata
     2341 ttcttcacat ccttaaaaga gaacttctct tcctcatctt ccgtaccggc agcaatggca
     2401 gcagcttcca tctgtttgtc cagcttcttg tccatcactg caaaaatgaa gaaagcaatc
     2461 ataccgccca acaacagaac caaacccaac aacaccggtg tggaaatacc gaaagcacgg
     2521 gccaaaggaa tggctacggc ataaccggct tgcgaaccga tacgtgctaa agcgacttgt
     2581 acccccatag ccgtggcaag ctctttcccc ttaaaccact tggctatgat tttggaaact
     2641 gtaataccgg cgacctccgc tcctactcca aaaatggaat aaccggcaaa agcaacaaac
     2701 acacccgttt tatagccaaa tatttcattg attccgaata aagtcgcgtc ggcaccggca
     2761 agtcccgtca ttgcatagta ttcaagtgct gtaccaccta ccatcaggat agttgccagc
     2821 tttccggtga aacggatacc aaagcggtcg aggattaatc ctccccaaat caacatcagg
     2881 aaaaaaacat tcagaaaact ataaccaccg gtaaagaatc cgaaatcggt actcgaccaa
     2941 gccaagtccg tttccaacat tgtcttcaac ggtgctacca cgtcgtttac ataataagct
     3001 gccatcatcg tgaaggcaac aatcaccaat gccccccaac gggtagcctt ggaatcattc
     3061 aatttaagtt tgagttgttc tgtcattgta ctatttggat ttcaatttat taatcagatt
     3121 gcataaatta ctgacaaagg taaataaata cttcatcaaa acgaaaaaag gctgacacct
     3181 tttcagtatc aacctttctc ttatttttcc aagcgggagt catccgcaat atccttatct
     3241 tattctgctg caggggcttc tgctgcagga gcaggagctt cagccggagt tgtagctgca
     3301 ggggcctccg attgcggagc ttctgtacct acgggcatgt tataaggatt agttttttct
     3361 tcttgttgcg cctgttccag aatcacatca ccgcccttgc ctgtggaaga aggaatagtg
     3421 taagcagaaa caatactgaa gactaccatg acagctgcca gagtccaggt tgctttttcc
     3481 aaaaagtccg tagtcttgcg cacacccata atttggttgg atgatgaaaa gcctgatgcc
     3541 agaccacctc ctttagaatt ttgaatcaat acaatgaagc acatcagcac agatgcaatc
     3601 agcattaaga taactaataa taaatacatt ttgttatttt gatttagcgt taataatcaa
     3661 tttctccaaa aatctgattt ggtctgcaaa gtaagcattt ttttttggat aattcaaact
     3721 taatttttta ataatttcaa gcgccttgtc atatcggtgc tgttttatat agattttggc
     3781 taaagtttcc gtaaaacagc tatcgtccaa ctcttccgtt accggcgata ctgagggttc
     3841 ttcctcttct tcagtctctt cctccttctc tacaagaaac tcccttctcg tatccgaggc
     3901 atccgaagac tcactctttt ggataaagtc atctatcaat tcatgcccgc gcagtttagg
     3961 cacttccgac tcatcttctg catccacacc gggttcttcc tgcattaaat aggccgtata
     4021 atccaccgca taatccagct ccgtatgctg tgaatgctct tcgggaacag tagccagaaa
     4081 tgcgtcaatc aaggaaaggg tacggtccac actcggctct ttctccaaat cgccggaaaa
     4141 cagcgacgag accttccggg atttcaaagt atagcggtca ccctctataa agtaaaacag
     4201 cacacgacgg tctgccacat acaacacagc cttgcgcaac tccgcgccaa agttgatgtc
     4261 gtgcagcaga tagaggtttt tcagatagag caaacggagc gactggaaat aaggatagcg
     4321 tgccaccaat gtgcgaagct cgtacaaagt atccctattc agcgtctcgg gatgctgaat
     4381 ccattgttgc aaatgggtag gcgtcatgag tttaccagtt agctacagtt gcattgaaaa
     4441 tctgttcggc aatgtctttc accatcaagg ttatcagctg gtcctgcact tcggtcagca
     4501 attttgagga atcataggtc tggaaagccg agaactgctg ttcaaagtcc tcctcatggt
     4561 tcgtgttatt ggtgtaacgc acgttgacag tcagcgtcac cttcaccttc gaagagtagc
     4621 cgctggcatc caccgattca ttatattgat tgtagccggt tatttctccg tctatttcca
     4681 ggtctcctcc ggaattcacc agttgcaggc gagtctgctg aatgaacata tccttcattt
     4741 tctggttaaa ttctgttgcc agcggtgcat atacatactc tgcccggttc tggaaatcgg
     4801 caatggaaat cgtttttacc tttgtatagt cgatagagct tatcggagca agtcccaact
     4861 tcatactaca tgaattcacc agaaataaca agcttaccaa caaggaagca aatgccgctt
     4921 ttttaatcca atccatattc ttttatcttt ctgtataacg tacgctcaga gatattcaaa
     4981 tcctgagccg cactcttacg cttgccgtga tgtttttcaa gcgccttacg tatcatttct
     5041 ttctccactt catccaggga gagtgactcc tccacatatt cttccgtatc ctggaatgtg
     5101 gcaaccgccg gattggctac cgttcccctt tcagccataa tctcatgcac caactttttc
     5161 aagtccgtta catcctggcg catatcaaac agaacctggt agagaatttc ccgttcactc
     5221 ccaaagctct tgtcctcctt cactccaaac aaggcaggca ggcgctgcat attgttctgc
     5281 tcaggcagat agcccttcag tatggatgca ttgatttcac gattggtctc aatgatggat
     5341 atctgctcgg tgatattctt caactggcgc acattacccg gccatgagta gcccagcaac
     5401 acttgcttgc cgtcttccgt cagctgaatg gcaggcatac ggtacttttc tgcaaagtcc
     5461 gaagcaaact ttcggaacag cagcaccacg tcttcaccgc gttcgcgcaa tggagggacc
     5521 tgaataggaa ctgtgttcaa acggtaatac aagtcttcac gaaaacgtcc gtcagcaatg
     5581 gcttgcgtca agttacattg gtagcggcaa caatacgcac atcggtcttt tccaccttag
     5641 aagaacctac tttgatgaat tcaccgctct cgagcacacg caacaagcgt gcctgggtag
     5701 gcaaaggcaa ttcgccgact tcatcaagga agattgttcc gccgttggcc tcaccgaaat
     5761 accccttccg ttcgccgata gccccggtaa atgcgccctt ctcatgaccg aacagttccg
     5821 agtcaatcgt cccttcggga atggctccac agttcacggc aatgtactgt ccatgcttgc
     5881 gccggctgta ctggtgtatt atctgcggaa agctctcctt tcccacacca ctctctccgg
     5941 taatcagtac agacaagtcg gtgggcgcta cctggatagc gatatcaatg gcacgcatca
     6001 gcgcttcatt gttgccgata atgccgaaac gtaattttac ttgttgtatt tccgcttttg
     6061 tcattctaca aatcttcttc tacactatcg agtttcagtt tgtcgctatc gtcacgtttc
     6121 tcgtaatatt gcttgcgcag cggatttgca tgtgcctctt tctcacgctg gcggttacgg
     6181 aacacatcta ttgccacata gatagcctgc cggaatgaat cttcagaggc gattcctttc
     6241 ccggcaatat cgtaggccgt gccatgagca ggcgaagtgc gtatcaccgg caagccggca
     6301 gtatagttca cgccctcgtc catagccaat gccttgaacg gtgccagccc ctggtcgtga
     6361 tacatggcca ggataccatc aaaatgggta aagttatctg agcccataaa cccgtctgcc
     6421 ggataaggac catagcaaag cataccctta gcagccattt cgttgatggc cggaatgata
     6481 atctcctgct cttcagttcc cagcaatccg ccgtctcctg catgcggatt cagcgaaagc
     6541 actgcaatac gcggtgcgct gatagcaaaa tcctgcttca aggagcggtt gaatatcttc
     6601 agtttttctt gtatcagttc tttggtgatg cttccggcta tctctttaac gggaatatgt
     6661 ccggtcacca atgctacccg gaagtcatct ttcatcagaa tcataagggc cttctcgcca
     6721 tctcccaatt tttgctctat atactccgta tgtccgggga aggcaaactc ctccgactgg
     6781 atggtatgct tgttgatggg agctgtgaca atcacgtcta tcattccctc cttatattcc
     6841 tcaatggctt tttccagtgc accaagtgca gctttaccag cttcaacgtc aggtttagag
     6901 aactcaacct ttacttcatc atccgtacag ttcactacac tcaagcgatt gggaaccgct
     6961 tcggaggcgg agttgacgat actgaagttg gtaggcaagt ccaatgattt acgatgataa
     7021 gctgccactt taggcgaacc gtagataatc ggcgtgcaca attccagcat caccgggtct
     7081 gcaaacgtct ttaaaatcac ttcataccct acaccattaa tgtcgccttg tgtaatgccg
     7141 actcttattt tgttgtcttc catttttatt acttattatt agtagtatct tttgaggtta
     7201 cgcctaccgg aatttccgca ccttcctgct tgctgccggg cagtttcaag gtatagagcg
     7261 aagcctccat ctgacgtacc agattacgtt tcattttatc aggtgaataa ataaatattt
     7321 cagatacgat aatacgctga ttggccttgt ccaaacgtac atgcgatacg aacggaccgc
     7381 ccatgaagtc accctttatg cgccacaagc cgcgggcctc cagtgcatag tctccctgca
     7441 cactgatggg gcgtacatcg gtcatcagag aatccgtcga catatacatg ccttcacggg
     7501 caccagggat gttagccttc atcacggaat cgcgtttatg aacaaaatat tctttagtaa
     7561 acgtatcctt atccgtataa ggataagagt agattacaaa gttctggtcg ccggtagctg
     7621 cattcgtacc tgcccagaag aagttctcac cctccttggt agatgtcagt tcgcccggca
     7681 cccatacatc gcaatcgaac tggcttttca ccttcgttgc tatatagtcg ctatgcttgt
     7741 ccttcaatac tgaaatctga cgattcattt ccgcatgagt aaagaaatcg atgattacct
     7801 gcctattctc ctccacaaat ttctcgaacg aagcctcgtc cggcgcctga atagtaagaa
     7861 tagactgagg agcagcatat acattccttg catacttgaa tttaggctgg gtatagaggt
     7921 ccttgttcac atcgacaata atgatattgc gaatcagttt taaagtggca tcataattgg
     7981 aaggggcagt atacatgatt cggaatgaac gttctgactg gggaagcccc ggaacatcag
     8041 aatcaagcac atcgaaaagc gccctaccgg caggacgttc ccacaagccg ggctccacca
     8101 ctaccagaac ttcatacgca cgaccactgg aggtcggagt aaacacaccc tttttaccac
     8161 caccgcaagc ggaaaaaagt gtcagtacga gaaccatact taaataaaac aagtgctttc
     8221 tcatatctct atcattttag ttttcacaaa gctacgaaga atgcgtaata tcctccctac
     8281 ctaagttaat aatttatatt aattcttctt tattctcctc ctgcttggca gtggacaaca
     8341 tgccacaagc ggcaaatata tcctctccac gcgatgaccg tatagtggta aacagaccgt
     8401 gcgaagtcag ataatcacgg aacgcagtca tggtttccat atcagcccct tcaagattca
     8461 ctccaggtat ggcatgaaaa cgaatcaggt taatccggca gtccagcccg cgtagcagct
     8521 tcagaagttc ctttgcatac ggtaacgagt cattcactcc tttgaaaaca atatattcaa
     8581 aagatagtct gcgctgtttg ctaaaatcat agtttcttaa caattccaca atctccgtga
     8641 tggagaacgc cttctctgcc ggcatcagtt cgcggcgttg caaaggtatc ggcgaatgaa
     8701 ggctgatagc cagatggcag tccgattcct caataaaacg ctgcaagccc ttcttcaatc
     8761 ccacagaaga aagtgtaaca cgcttgggac tccacgcata cccataagag gcggtcatta
     8821 tttccagcgc tttcaatacc tcgtccagat tatcaagtgg ttcacccatg cccatcatta
     8881 ccacattggt aagcttgtcc ctttcgggca acgaattgat ttgattaata atctggttgg
     8941 atgtcagatt ggcagtaaaa ccttgtttgc cggtcataca gaacttgcaa ttcatcttac
     9001 agcccacctg agaggagaca caaagcgtag cccggtcttc gtcgggtata tagacagctt
     9061 ccacgaaatg cccctcgcct gcccggtaca agtatttcac cgtaccgtct acagagcgca
     9121 tggcatctac cggcgcttcg gcacctacct catagatttc tttcagcaat tcccgatgct
     9181 tcaacgaaag attgctcatt tcgtctatag aagtcacctt cttgtcatac agccaggaag
     9241 ctatctgctt ggcagagaaa ccaggcattc ccagattctt caccacattc tgcaattcag
     9301 agagcgtcaa gcccaataga ggtcgtttct gcatatcgtt tttcattaaa acaaaactct
     9361 ttcaagaatg caaaggtagg aataaagttg cacaaagaca acggagagta tagaaaatga
     9421 aatgtacaga gaatgaaaaa gccgcccgga aataccggac ggcttttcaa tatgtttttt
     9481 tattcttaga agaataaata acgttggtct tttacgttgg ctttcagata caagtcactg
     9541 atgaactggc ttgccatgcg tgcgtgcatg ttagccaagt tagcctcttc agtttccttg
     9601 ttgaatgttt cgttcagttt ctcttttgca taaggttgca gaacgaatac accaccatta
     9661 cccttgatag gagcactcag cttgttcact tcggcaatag aagcgtatgc gcctaccaga
     9721 ggttcgctgc tacgcaatgc cgggatatag gcaggagcag agaaagtaac gtgctttaca
     9781 gaatcactaa cagcatttgc catattcttg tactgctcga acgaagttgc attggcagcc
     9841 ttcatatcag ccataatctt ctctgctttc ttatcacgga gaatttcagc tctcaactgg
     9901 tcctttacca aagccagtgg gcgataacct tcaggaacaa tacttgcaac acctactacc
     9961 agcatacggt cgctctcgcc acattcgtac aaaccggaaa cttcaccggc ctttgcctca
    10021 aacgcccatt tcaaagcatc tttggtacct ctgataccac cgataccatg ttcagagctg
    10081 tacaagtcgg ctctatccaa caacttataa ccggcatctt ccgcattggc aatcattttc
    10141 tctaaagtat tgtttgcagc gataaactgg ctgaattcat tgtatgcctt actgtaagtt
    10201 tccttactga attctaccgg acgcttgata acggctacct tatatttatc cttgacagcc
    10261 ttcttgttgg ttacctgcaa aatgacattt gcttgtccca acgccagatt ggtcagttcg
    10321 ttctgtccca aagtagtgac agcagtaata tatttcaagt tgtcaccgtc aatctgtgcg
    10381 ccttcgtagt tagctgaaga gatccaggta ggctcaccgg tctgaccgta cttcttcgca
    10441 atttcagcaa agctggcacc acccttaata gcattgtaga tgctgtcggc taaagtcttc
    10501 gtcttttcag catcttcggc aactacctga atctgacgga actcgataga gtccggcata
    10561 gcagcagtag ccaatttctt gaaagagtta agagtattgt ccgatacgtt ataataaggt
    10621 ccgaatacac cacccaccgc aacagagtcc aaacgggctg tcacatcagc aggcagagac
    10681 ttagtagtgt agaacaagtc tgtataagga gcttcggaac cggtagaacg gataaaggta
    10741 gtatagtcag aaggattggc agtaagttgt tcagtgtatt cttccatttc cttctggaga
    10801 gcagctctgt cttctgcact tgcagtaact tgcacatcaa tgaacttgat attgcgagtt
    10861 tccacatatt gcttgaactg ttctttcttc ttgtcgtatg cagctttcaa atcggaatcc
    10921 ttgataacga tggtagagtc aacgatagaa gaatagggaa ctgcagcaag cagcaggtct
    10981 gactgctcta ctcttgcatc aaaagcgtcc tgagcttcta ccgggttgga gaaaagagat
    11041 tttgtaatca aagcctgata cttctcctga agacgtgcct ggataaggga cttttcgagg
    11101 aaagaccaga acttgtacat ggattcatag tattctgcat attgtgaagg catctgtgcc
    11161 ttattcattt ttgaatagtc caccaagaac ttcttcaaca tatccttatc aaacgcaccg
    11221 gtctgaggat tacggaacgg agtctgttgc agcatcggat gcacaccggc attaatgata
    11281 gcctgaatct cagccttcga tacaaccaga ccgagtttct ttgcttcctt ttcaatcagc
    11341 ttattattga cgtatgttct ccatacttca tctttgattt ggtttgtctg ctcatcgctc
    11401 aatgcactgt tgccactgga gaacttgatg acttctgtat attcttctac caatgcttga
    11461 aaatcctgag cggaaattga ttccccgttc acttcaccta cgtcttgtga ctggtgtggc
    11521 tgaagcactt tccacgcgtc acctgcgatg aaagcaaaca gcgccaaacc aataacaatc
    11581 accaataaag gtcctttaga ccgaatgttt tgtaatgttg ccattttagt taatatgatt
    11641 tatttgttta ttattatttt cctaacatgt tcatt
//
