LOCUS       c00146_gnlPro..        19984 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NLOPLDIL_146.
ACCESSION   c00146_gnlPro..
VERSION     c00146_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 16:07:05
            Original ID  :: gnl|Prokka|NLOPLDIL_146
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 11890
            Orig. end    :: 31874
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..19984
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[21890:26599]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14709
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..19984
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..19984
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(459..830)
                     /locus_tag="ctg146_21"
                     /transl_table=11
                     /translation="VGKSIVRKVGKIDGSQFLQRLNSLRSLHSKLCHVVGSIFQFSAFR
                     VMRHTPVPVFLNVRRIHDKQVFLRLIMIDQKVVYNASVVIGEAGILYFPRCEGSYVIGS
                     HFLQKVQSMGTFHPEFSHV"
     CDS             complement(1074..1205)
                     /locus_tag="ctg146_22"
                     /transl_table=11
                     /translation="MTGDTAVYHFKSHQLTGSAFRFLFFQHRAIGEVLSLHKLGNPS"
     CDS             complement(1208..1456)
                     /locus_tag="ctg146_23"
                     /transl_table=11
                     /translation="MMPHDKFFILLILVIHSNYCLRNGGFTTTAFSLRPRMSMQISVPT
                     LLYSGLIYPIPIPILRVGDIVPEVTTPMAVPSVLYSS"
     CDS             complement(1495..2256)
                     /locus_tag="ctg146_24"
                     /transl_table=11
                     /translation="VAYWDDNEDAYAVSLVADIGAIASLLSIPATDRLGMKYKTSQEIS
                     SDRLARQLLAFKGYNPDGIASALGKIIGYYNLHQRNKDIPRYGSIGNLQKRIEKAGESH
                     SLSARPYLRTTSDVVSFNASMNYANKRYKETARLIRKNIDNRLATDNDYIILVKAEMAL
                     SNTEEVNNRCLAMLDKAQEMAGTSPNLDIYKQKILLLMRMNKQAQAADILKEYITLLSA
                     YEGQGIEGTEKEWTNKEIGWANQMLDRISRI"
     CDS             complement(2343..3128)
                     /locus_tag="ctg146_25"
                     /transl_table=11
                     /translation="MKRLATLFILTILVATAGFAKPKKYKDLSGNIAVKGELTKEYRQS
                     PAGTPVIIRRVVKMKNPGESSNNICYAVEMNGIQETIPLNEMGHIAISAPQTDREFWQQ
                     IYLKNHLYEYFSDRGYKHKLRQEIDEECLEYLDKLNEIAYQEDYIVSYVQGVFSKLNAT
                     TIDSNRGESLNIRIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX"
     CDS             complement(3310..3561)
                     /locus_tag="ctg146_26"
                     /transl_table=11
                     /translation="MKKGIHPENYRPVVFKDMSNGDVFLSRSTCNTKETIEFEGETYPL
                     VKLEISSTSHPFYTGKSKLVDTAGRVDKFMSRYGNRKK"
     CDS             3750..4220
                     /locus_tag="ctg146_27"
                     /transl_table=11
                     /translation="MRKLLVLCSFWLCVATLGAQNAERKLYSVAFYNLENLFDTIHDAG
                     KNDYEFLPDGSYQWTAKKYESKLQNLSKVLGSLSRDLVPEGPAFIGVAEAENSRVLEDL
                     VKQPAISNYEFVHYEGPDRRGIDCALLYDPKQFSVTHSKLVLLLLLRGIRCT"
     CDS             4211..4756
                     /locus_tag="ctg146_28"
                     /transl_table=11
                     /translation="VHLTRGFLIVDGQLAGERVCVIVNHWPSRGAKSPVRVHAARQVKA
                     LKDSLMRSDKKLKLIVMGDMNDDPMDESMEVLGARKYPKQVKKGELYNPWWETLEDKGV
                     GTLLYRGKWNLFDQIVISKPLLKAKKGLRYDHNEVFIRDYLIQQDGKYKGSPLRTHGGR
                     TWLNGYSDHLPTIIYLKN"
     CDS             complement(5057..5296)
                     /locus_tag="ctg146_29"
                     /transl_table=11
                     /translation="MFATQFLSVLNSTLSHVTQQRSVGILTGTLRYLKNNRRLCFNCSL
                     DDSLHLFHIVEVECRNSISTFDSLSKHLSCVYQS"
     CDS             complement(5390..5524)
                     /locus_tag="ctg146_30"
                     /transl_table=11
                     /translation="MVFCRNFIFYTGQYTEFAFYSYVELMGIVNYLLSQCNVFFVRKV"
     CDS             5607..5705
                     /locus_tag="ctg146_31"
                     /transl_table=11
                     /translation="MVHTSSNPNNATLTLLPVVWFLLLWNLPFWML"
     CDS             6136..6228
                     /locus_tag="ctg146_32"
                     /transl_table=11
                     /translation="MVKFAGYFRSGCFNVYNSLFPLTKQSVSLN"
     CDS             6266..6376
                     /locus_tag="ctg146_33"
                     /transl_table=11
                     /translation="MQKHFVPIRKNTLFLHIRTLCFSILEQSVHRYELTD"
     CDS             complement(6520..7794)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg146_34"
                     /sec_met_domain="Alpha-amylase (E-value: 7.8e-51, bitscore:
                     165.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGGSYHGYATTDYYKVDPRFGTNEEYKQLIEKAHARGIKIVMDM
                     IFNHCGVEHVWIKDMPSKDWFNNPDHENNFVQTSFKLTPHVDPYTSQYDADQMNDGWFV
                     PSMPDLNQKNPHVYRYLVQNSFWWIEFANIDGIRMDTYPYADYDAMSNWMKELNEEYPN
                     YNTVGETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKINTAKNEQTETWFKGL
                     DRIYNNFVYDFLYPNPASVLAFIENHDTDRFLGEGNNLPMLKQASTLLLTTRRIPQLYY
                     GTEVMMNGVKSKSDGYVRKDFPGGWTGDATNALTPAGRTKIQNECYDFYKTILNWRKGN
                     DVIAKGSMVQFMVQNGVYAYARQYEGKTIFVMLNGTDAETTVPLKFYKEILKDSKQGKD
                     ILSGKAITFGEELKMGPRESLVIEL"
     CDS             complement(7791..8309)
                     /locus_tag="ctg146_35"
                     /transl_table=11
                     /translation="MNVNKIDPPFWYTGMQNPELQLMVYGEGIGNAAVSVNYPGVSLSS
                     TVKLESNNYLLVYLKLDKDVKPGKFNLTFTEGKKKLVKEYELKARNKKGCEHKGFDASD
                     ALYLLMPDRFANGNPDNDQIAGMAEYKIDRNDPNARHGGDLAGIEQHLDYFSDLGVTAS
                     GLLRYWKTT"
     CDS             complement(8480..9358)
                     /locus_tag="ctg146_36"
                     /transl_table=11
                     /translation="MGQVYDNTEIMHVIDAYLDIQKRYPNDYLSAAKLGNIYVAGHQYE
                     DAINITEKYRSIDSTNVLVNRINAQAYCLNKDYPKAIERYEQLLQEKDSSFQTCFYAGI
                     SYYALEDFYPAHDLLERALKDDNTNINVLYYLGRACSKTSWKEDGVTYLETAVSLAMPS
                     DSVMSRLYVGLADCYKMAFQYTDQANTLLTQYEKYDRQKHKLLYDAAFIYYYYLKDASK
                     AERYLTAYLKTRPKNSKDKVQEVDADGVPIIGEDNRYNAAENWLKDIREKRKKEDFFKG
                     KVDTASVTPIK"
     CDS             9478..9594
                     /locus_tag="ctg146_37"
                     /transl_table=11
                     /translation="VRIYCPDLCGAHFGSNPVPRYIWQVICSIRQLQCMPGD"
     CDS             complement(9628..9843)
                     /locus_tag="ctg146_38"
                     /transl_table=11
                     /translation="MIYCMRKLFISLCFSACCSLLAAQTTNPIQEAMANYDYETALMLI
                     DQETPTVPLLYQKGKALKGWAITLKL"
     CDS             complement(10001..11161)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg146_39"
                     /sec_met_domain="OAD_beta (E-value: 1.8e-152, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11163..11597)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg146_40"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.1e-21, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             complement(11621..12553)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg146_41"
                     /sec_met_domain="OAD_gamma (E-value: 4e-17, bitscore: 54.3,
                     seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFW
                     ADGEPRRGTFHTNFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQ
                     WEVKGGSEDKYVTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISF
                     KIIGKISVNLSKRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVED
                     TILTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             complement(12585..14138)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg146_42"
                     /sec_met_domain="CT_Btheta (E-value: 4.9e-291, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             complement(14197..14709)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg146_43"
                     /sec_met_domain="Glyoxalase_4 (E-value: 6e-25, bitscore:
                     79.3, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFFIKEEFSFFVLLYTFIKKDTILTLIYIVMKISHIEHLGIAV
                     KSIEEALPYYENVLGLKCYNIETVEDQKVRTAFLKVGDVKIELLEPTSPESTIAKFIEK
                     NNGNGGMHHLAFAVEDGVAGALAEVEGKGIRLIDKAPRKGAEGLNIAFLHPKSTLGVLT
                     ELCEKPE"
     CDS             14939..16168
                     /locus_tag="ctg146_44"
                     /transl_table=11
                     /translation="MPLATMAQNDTLGHERNITLSEAIVLARTQSVDAAVALNELKTAY
                     WEYRTFRADLLPEVNFTGTLPNYNKSYSTYQNSDGSYSFVRNNTLGLSGQLSVDQNIWF
                     TGGKLSLTSSLDYLKQLGSGGAKQFMSVPVSLELTQPVLSENDLLQLKLNSLQGKADVT
                     EAESNLNAKMFQLRSFLGVSEQESLNPVLPATVPDIKMEYDRVLNKALERNSFAQNIRR
                     RQLEADYEVATARGNLRSIDLFASVGYTGQNHEFSSAYRDLLDNQIVQVGVKIPILDWG
                     KRRGKVRVAKSNREVVLSRIRQEQMDFNQDIFLLVANFNNQAQQLDIAEEADVIAEKRY
                     KTSVETFMIGKISTLDLNDAQNSKDEARQKHISELYYYWYYFYQLRSLTLWDFERDTEL
                     EADFEEVVRG"
     CDS             16312..17673
                     /locus_tag="ctg146_45"
                     /transl_table=11
                     /translation="MILIIDDDSAVRSSLSFMLKRAGYEVKTAPSPREAMDIVRAEAPA
                     LILMDMNFTLSTTGEEGLTLLKQVKVFRPDVPVILMTAWGSIQLAVQGMQAGAFDFITK
                     PWNNAALLQRIETALELTAAPKEVPEEQTTALNRSHIIGKSKGLMEVLNTVARIARTNA
                     SVLITGESGTGKELIAEAIHINSQRVKQPFVKVNLGGISQSLFESEMFGHKKGAFTDAS
                     ADRIGRFEMANKGTIFLDEIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKVDVRVVSAT
                     NADLRKMVSERTFREDLFYRINLITVKLPSLRERREDIPLLARHFADRQAEVNGLPRTD
                     FSADALNFLSRLPYPGNIRELKNLVERTILVSGKPVLDATDFDAQYLRHDEPAKAAEGT
                     SFAGMTLDEIERQTILQALEQHKGNLSQVAVSLGISRAALYRRLEKYNIQVPCA"
     CDS             17664..18977
                     /locus_tag="ctg146_46"
                     /transl_table=11
                     /translation="VRIKFFFFILVLFLLGLGGMLVYLLSGKPSLYLYVLEGLIGFILI
                     YLIVFYNKIVKPMNTIGSGMELLREQDFSSRLSRVGQYEADRIVNIFNRMMEQLKNERL
                     RMREQNHFLDLLIQASPMGVIILTMDDEVSQLNPMAVKMLGVRMEEAMTKRLDQMDSPL
                     AAELSSIPKDETAVVRLNDANIYKCTHSSFIDRGFKHPFFLIERMTEEVMRAEKRAYEK
                     VIRMIAHEVNNTTAGITSTLDTVEQALSTEDDMEDICDVMRVCTERCFSMSRFITRFAD
                     VVKIPEPTLAPVQLNELVSMCKRFMEGMCNDRNIELRLECDPEVGMVRMDASLFEQVLV
                     NIIKNAAESIEGDAGENGQQGEIIVRTTAPASVEVVDNGPGISKETEAKLFSPFFSTKP
                     NGQGIGLVFIREVLSRHGCTFSLRTYSDGLTRFRILFN"
     CDS             complement(19011..19982)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg146_47"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.1e-18, bitscore:
                     56.1, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.00027, bitscore:
                     11.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RVTKIHANRMNNEGMHLWQYSDEDIDRLKSPKIKALFVTNPSNPP
                     SYTLSPDTMARIVSIVRNDNPNLMIITDDVYGTFSPHFRSFMAEIPYNTLCVYSFSKYF
                     GATGWRNAVIALHEFNLFDKLIAKLPKEKREILHHRYSTLTLEPEKLKFIDRMVADSRQ
                     VALNHTAGLSLPQQMQMGLFAAFALLDKENKYKQKMQEIIRRRLHALWENTGFTLTEDP
                     LRVGYYTEIDMLVWAKKFYGDDFVEYLKRTYSPLNVVFRLAKETSLVLLNGGGFDGPEW
                     SVRASLANLDEKDYATIGQGIKKILEEYAKEFFKNGKAKGKN"
ORIGIN
        1 acttcgcgac caatactata atatgcgcga gcagattgaa ccggtgatgc atatcatcga
       61 caccgctttt gccgccatga aggcggtagg tgtagagcct cgtgtaaaag ccattcgcgg
      121 aggtacggac ggtgcccagc tctctttcaa gggcctgcct tgtcccaata tctttgccgg
      181 tggcttgaac ttccacggcc gctatgagtt cgtgcctatc cagaacatgg agaaagccat
      241 gaacgtcatc gtcaagattg ccgagctcgt agcaagcaaa tagataattc ataactcata
      301 actctaatag ttccatgaaa accactccgt ttaccgaaaa acacatctcg ctgggtgcca
      361 agatgcacga gtttgcggga tataatatgc ctatcgagta ttccggcatc attgacgaac
      421 atcttacagt atgtcagggt gtcggtgtat tcgacgtctc acacatggga gaattctggg
      481 tgaaaggtcc ccatgctttg gactttctgc agaaagtgac ttccaataac gtagctgccc
      541 tcacacctgg gaaagtacag tatacctgct tccccaatga caacggaggc attgtagacg
      601 accttctggt ctatcattat gagccggaga aatacctgct tgtcgtgaat gcgtcgaaca
      661 ttgagaaaga ctggaactgg tgtgtgtctc ataacacgga aggcgctgaa ttggaaaatg
      721 cttccgacca catggcacag cttgctgtgc aaggaccgaa ggctattcag acgttgcaga
      781 aactgacttc catcaatctt tccgaccttc cttactatac ttttacccac ggtgagtttg
      841 ccggagaaaa ggatgtcatt atctccaata ccggatatac cggtgcgggt ggttttgagc
      901 tttacttcta tccggaggct gccatgaaga tttgggatgc cgtgttcgag gcaggcgcgg
      961 agttcggcat taagccagtt ggtctgggtg cgcgcgatac gcttcgtctg gaaatgggct
     1021 tctgtttgta tggcaatgat ttggatgaca ccacttcgcc cattgaagcg ggtttaggat
     1081 ggattaccaa gtttgtggag ggaaagaact tcaccaatcg cccgatgctg gaaaaacaga
     1141 aagcggaagg cactacccgt aagttggtgg gatttgaaat gatagaccgc ggtatccccc
     1201 gtcatggtta cgagctgtat agtacagacg gtactgccat cggtgtggtt acctccggaa
     1261 ctatgtcgcc tacccgcaag attggtatcg gaatggggta tatcaggccc gagtacagca
     1321 aagtcggtac ggaaatctgc attgacatgc ggggacgtaa gctgaaagct gtggttgtga
     1381 aaccgccgtt ccgcaaacag taatttgaat gaataactaa aataagaaga atgaagaatt
     1441 tgtcatgcgg catcatcgcg cagtcaaatt cttcattctt agttattcct ttctctatat
     1501 tctgcttatc ctgtccagca tttggtttgc ccaacctatc tctttattgg tccattcctt
     1561 ttcggttcct tctatgccct ggccttcgta ggccgaaagc aaggtgatat attctttcag
     1621 tatatcagcg gcttgggctt gtttgttcat acgcatcaat aatagtattt tttgtttata
     1681 tatgtccaga ttggggcttg ttcctgccat ctcctgggct ttatcaagca tggcgaggca
     1741 gcggttgttc acttcttccg tattagacag tgccatttcc gcttttacca ggatgatgta
     1801 gtcattgtcc gtggctagtc tgttgtcaat gttcttgcgt atcagccggg cagtttcctt
     1861 atagcgcttg ttggcgtagt tcatacttgc gttgaaagaa acgacatcgc tggtggtccg
     1921 taggtagggg cgggcactca ggctatggga ttcaccggcc ttttctatac gcttttgcag
     1981 gttgccgatg ctgccgtagc gaggaatgtc cttgttgcgt tggtgcaggt tgtaataccc
     2041 tataatttta ccgagggccg atgcgattcc gtcgggatta tagcccttga atgccagaag
     2101 ttggcgcgca aggcggtctg aagagatttc ctgggaagtt ttgtatttca tccccaaccg
     2161 gtccgttgcc ggaatgctca aaagggaagc gatggctccg atatctgcca ccagactgac
     2221 ggcataagca tcttcattat cgtcccagta ggccacatcg agggctgcgc tggcggtagt
     2281 ggcaaagaca tctgcccaaa aagctgcacg cttggcacgc cgctcggcac ggtaaatgtt
     2341 gtttacnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2581 nnnnnnnnnn nnnngatgat acgtatgttc agactctccc cgcgattgct gtcaatggtg
     2641 gtggcgttca acttggagaa cactccctgc acgtacgaaa cgatgtaatc ttcctgatag
     2701 gctatctcat tcagtttgtc gagatactcc aggcactctt cgtcgatttc ctggcgcagt
     2761 ttgtgcttgt agccgcggtc gctgaaatat tcgtaaagat ggtttttcaa gtatatctgc
     2821 tgccagaatt cccggtcagt ttgcggagcg gatatggcaa tgtgccccat ctcattcaaa
     2881 ggaatggtct cttgtatgcc gttcatttcg acagcatagc aaatgttgtt gctgctttca
     2941 ccgggattct tcattttgac aacccggcgg ataatgaccg gtgtaccggc gggagattgc
     3001 cggtactctt ttgtcaattc tcctttgaca gcgatgtttc cgcttaaatc tttgtacttt
     3061 ttgggcttgg caaatcctgc cgttgcgaca aggattgtca ggatgaatag ggtggcgagt
     3121 cgtttcatga ttagtatatg ttttcggttt tgatgataca aaaataggga agtgtttttc
     3181 tcctttctcg tttttttccc tattctgtga taggagattc cctatttatc ggtcctgcag
     3241 tgggaggcgg aaacaaaaaa gggaaccttt cagtgaaaga ctcccttttt tcagtttgct
     3301 tgaaactgat tatttcttac ggttaccgta gcggctcatg aacttatcaa cacgaccggc
     3361 ggtgtcaacc agcttggact taccagtgta gaacgggtga gaagtgctgg agatttccag
     3421 ctttaccagc ggataagttt caccttcgaa ttcgatagtc tctttcgtgt tgcaagtgga
     3481 acgagacaag aatacatcac catttgacat atctttaaat actaccggac ggtaattttc
     3541 aggatgaata ccttttttca ttttgatatt ttcttttaaa aatttatatt ctgttactat
     3601 tttggtaata aatagtgtaa tggtcttctt ttcagagcgc aaagatagtg caagttggag
     3661 actctacaaa ataaattcag atttattttt atttagtagg tttatcgcat tttatttctg
     3721 atttttgcag gacttaatct tgtgaattta tgaggaaact acttgtctta tgctctttct
     3781 ggctgtgcgt ggcaacgctg ggggcacaaa atgcggaacg gaaattgtat agtgttgcgt
     3841 tctacaatct tgagaacttg tttgatacga ttcatgatgc aggtaagaat gactatgagt
     3901 tcctgcccga cggcagttac caatggacgg caaagaagta tgagtccaag ctgcagaacc
     3961 tttccaaagt gttgggttcc ctttcgcgtg atttagtgcc ggaaggtccg gcattcatcg
     4021 gtgtggcaga ggcggagaac agccgggtgc tggaagacct cgtgaagcag ccggccattt
     4081 ccaattatga gttcgtgcat tatgaaggac cggacagacg gggtatagac tgtgccttgc
     4141 tgtacgaccc gaagcagttc agcgttaccc actcgaagtt ggtgcttcta ctccttttga
     4201 gggggatacg gtgcacttga cgcgcggctt cctgattgtg gacggacaac tggcgggaga
     4261 gcgtgtctgc gtgatagtga accactggcc ctcccgtggg gcgaagtcac cggtgcgtgt
     4321 gcatgcagcc aggcaagtaa aggccttgaa ggactctctg atgcgtagcg acaagaagct
     4381 gaagctcatc gtgatggggg atatgaatga cgacccgatg gacgaaagca tggaggtgct
     4441 gggagcgcgc aaatatccga agcaggtgaa gaaaggcgaa ctctacaatc cctggtggga
     4501 gacactggaa gacaagggag tggggacatt gctctatcgg ggcaagtgga acctgtttga
     4561 ccagattgtc atttcgaaac cgttgctgaa ggcaaagaaa gggttgcgct atgaccacaa
     4621 tgaagttttc atccgcgatt atctgattca gcaggatggc aaatacaaag gttccccctt
     4681 gcgtacgcat ggaggcagga cttggctgaa cggctacagt gaccatttgc cgaccatcat
     4741 ctatctgaaa aattagtatt acataataat gtgtaaacag atgccggaga gcaaacatgt
     4801 tctccggctt ttttgttgat agaagtatag atggcaaaag tatggctggc agagataaat
     4861 gcaaagagtt tgtaatatag agattacaat aatctgttaa atgaagccaa tagctttaaa
     4921 atagaatgga tttggtagga tgagccggat attttattcc tctcaagttc tttactttaa
     4981 aggataatga ttacttttgc gtagaatttt aattcactaa caataaaatt taaacaaaat
     5041 ggttaattac aaagatttag gactggtaaa cacaagagag atgtttgcta aggctatcaa
     5101 aggtggatat gctattccgg cattcaactt caacaatatg gaacagatgc aggctatcat
     5161 caaggctgca gttgaaacaa agtctccggt tattcttcag gtatctaagg gtgcccgtca
     5221 gtatgccaac gctacgctgt tgcgttacat ggctcagggt gctgttgagt acgctaagga
     5281 attgggttgc aaacatcctg aaattgttct tcaccttgac cacggagata cattcgaaac
     5341 ttgcaagagc tgtatcgact ccggtttctc ttcagtaatg attgacggtt cacaccttcc
     5401 gtacgaagaa aacgttgcac tgactaagaa ggtagttgac tatgcccatc agttcgacgt
     5461 aactgtagaa ggcgaactcg gtgtattggc cggtgtagaa gatgaagttt ctgcagaaca
     5521 ccatacatat actaatcctg aagaagttat tgacttcgct acccgtacag gttgcgattc
     5581 actggctatc tcaatcggta cttctcatgg tgcatacaag ttcaaacccg aacaatgcca
     5641 cgttgaccct gctaccggtc gtctggttcc tcctcctttg gaatttgccg ttctggatgc
     5701 tgtaatggag aaacttccgg gattccccat cgttcttcac ggttcttctt cagttcctca
     5761 ggaagaagtt gatactatca acaagtatgg tggtaagctg gaagctgcta tcggtatccc
     5821 cgaagagcag ttgcgtaagg ctgccaagtc tgctgtttgc aaaatcaaca tcgactctga
     5881 ctcacgtctg gctatgacag ctgctatccg caagacattt gctgaaaaac cggcagaatt
     5941 cgacccgcgt aagtatctgg gtccggctcg tgacaatatg gaaaaactgt acaagcataa
     6001 aatcatcaac gtgcttggtt cagagaacaa attggctcaa ctggactaat cgaaagataa
     6061 tccgaatata gcgtcagccc ttgcaatatt gatgttgcaa gggctgactt gttatatata
     6121 ggccggtgtt gtgggatggt taagttcgcc ggttatttca gaagcggatg tttcaacgtg
     6181 tacaacagtc tgtttccttt aacaaaacag tctgtttccc ttaactgaac agtttgtttc
     6241 aataaagaga acacttcgtt ccaatatgca aaaacacttc gttccaatac gtaagaacac
     6301 tttgtttcta catatccgaa cactttgttt ctctatactg gaacaaagtg ttcaccgtta
     6361 tgaactaaca gattagctat atttgagacc ggtgaaaagc atatccccgt gacacctatt
     6421 ccatactaaa aatcccttgc agatggctgg caggcgaggt gtctgcaagc tatctgcaag
     6481 ggagatttgc aagaatgagc tctctgtgtg gagtgcgcgt tataattcta tcactaatga
     6541 ttctctgggg cccatcttca gctcttcacc gaaggtgatg gccttgccgc taagaatatc
     6601 ttttccctgc ttgctgtctt ttaggatttc cttgtagaat ttcaaaggaa cggtggtctc
     6661 tgcatctgta ccgttcagca tcacgaatat cgtcttgcct tcgtactggc gtgcgtaggc
     6721 ataaacacca ttctgtacca tgaactgcac catgctgcct ttggcaatca catcgtttcc
     6781 tttgcgccag tttaggatgg tcttgtagaa gtcgtagcac tcgttctgta ttttggtacg
     6841 tccggctggg gtcagtgcgt ttgttgcgtc accggtccat ccgccgggga agtccttgcg
     6901 gacatagccg tcgctcttgc tcttcacgcc attcatcatg acttccgttc cgtagtagag
     6961 ttgcggaatg cggcgggtgg taagcagcag ggtagaggct tgcttcagca tcggaaggtt
     7021 gttgccttcg cccaggaagc ggtcggtgtc gtggttttcg atgaatgcca gtacggaagc
     7081 ggggttgggg tagaggaagt cgtatacgaa gttattgtat atgcggtcca gtcccttgaa
     7141 ccaagtttcg gtctgttcat tcttggcggt gtttatcttg tcgaagaagc tgaagtccat
     7201 aacggtcttg aggttactgt tcttgggggc tgatagcttg gaatccttct gccaccaggc
     7261 ggtgtaggcg ggttcggtaa cccaggtctc gcccacggtg ttgtagttgg gatattcttc
     7321 gttgagctct ttcatccagt tgctcatggc atcatagtcg gcatacgggt aagtgtccat
     7381 gcggatgccg tcgatgttgg cgaattcaat ccaccagaaa ctgttctgta ccaggtagcg
     7441 gtaaacgtga ggattcttct ggttgaggtc gggcatggaa ggtacaaacc agccgtcgtt
     7501 catctggtcg gcatcgtact gggaagtata agggtctacg tgcggggtca gtttgaagga
     7561 ggtctgcacg aagttgtttt cgtggtcggg gttgttgaac caatctttgg agggcatgtc
     7621 cttaatccat acatgctcta cgccgcagtg gttgaaaatc atgtccatta cgattttgat
     7681 gccgcgtgca tgggcttttt caatcagttg cttgtattct tcgttggtac cgaagcgcgg
     7741 gtctaccttg tagtagtctg tggtggcata gccgtgatag gaaccgccgg tcatgttgtt
     7801 ttccagtacc ggagtaaacc agaggctgtg acgccgaggt cggagaagta gtccaggtgt
     7861 tgttcgatgc cggcaaggtc accgccgtgg cgtgcattgg ggtcattgcg gtctatcttg
     7921 tactcggcca tgcccgcaat ctggtcattg tccggattgc cattggcaaa gcggtcgggc
     7981 atcagcaggt acagtgcgtc ggaggcgtcg aaacctttat gttcgcaacc tttcttgttg
     8041 cgtgccttca gttcatattc ctttacgagt ttcttttttc cttcagtgaa ggtgaggttg
     8101 aatttgccgg gttttacatc cttgtccagt ttcagataga ccaggaggta gttgttgctt
     8161 tccagcttga cggtgctgct caatgagacg ccgggataat tgacggatac tgccgcgttg
     8221 ccgatgcctt cgccatagac catcagctgg agttccgggt tctgcatgcc ggtgtaccaa
     8281 aacggagggt cgattttgtt cacattcata gctgcatacg tactgaggga gagtaagagt
     8341 gttcccaaga ttaagaatac ttttttcatg atagtaactt tacggttaat ttttgcgcta
     8401 atttaaaaca aataacggag aaagttaatc tttctccgtt actgtacctt attatattat
     8461 gcaaacgttt tcattggggc tatttgatgg gggttacgct ggcggtatcg acctttccct
     8521 tgaagaagtc ctctttcttg cgcttttctc tgatgtcctt cagccagttt tcggcggcat
     8581 tgtatcggtt gtcttctccg atgatgggaa ctccgtccgc atctacttcc tgcactttgt
     8641 ccttgctgtt tttcggacgg gttttcaggt aggccgttag gtatctctct gctttggacg
     8701 catctttcag atagtaataa tagataaagg ctgcgtcgta gagcagtttg tgtttctgcc
     8761 ggtcgtattt ttcgtattgc gtcagaaggg tattcgcctg gtcggtgtat tgaaatgcca
     8821 tcttgtagca gtccgcaagc cccacatata ggcgggacat gacactgtcg ctgggcatgg
     8881 cgaggcttac ggcagtttcc agataagtca ctccatcctc tttccatgat gtcttggagc
     8941 aggcgcgtcc cagataatag agaacgttga tgttggtatt gtcatcttta agagcccttt
     9001 ccagcaggtc gtgtgctggg tagaagtctt cgagggcata atagctgatt ccggcgtaga
     9061 agcaggtttg gaaggagctg tctttttcct gtaacagttg ttcatatctt tctattgctt
     9121 tggggtaatc tttgttcagg caataggctt gggcattgat gcggttcaca aggacgttgg
     9181 tggagtctat ggaacggtat ttctccgtta tgtttatggc gtcttcatac tggtggcctg
     9241 ctacatagat gttgccgagt ttggcagcag acaggtaatc attgggatat cttttctgta
     9301 tgtccaggta ggcatctatc acatgcatga tttctgtgtt gtcatagact tgccccatac
     9361 tttcggctct aaggtgtagt acataggcgg aactgtccct ttctgccagc aggttgcttt
     9421 cctttagaga ctcacggtat ctcttcatgt tcatcagcag actgatatac tggatgcgtg
     9481 cgtatttatt gtccggattt atgtggagcg cattttggta gtaatccagt gcctcgctat
     9541 atttggcaag tgatttgcag cattcggcag cttcaatgta tgcccgggga ttgagagaat
     9601 cctgagctac gacttcctga aatacgctca gagcttcaag gttattgccc agcctttcag
     9661 cgctttccct ttttggtaga gtagggggac ggtcggggtt tcttgatcga tcagcatcaa
     9721 ggctgtttca taatcgtagt tggccatcgc ctcttgaatg ggatttgtgg tctgtgccgc
     9781 cagaagcgaa cagcatgcac tgaaacataa ggagataaaa agctttcgca tacagtatat
     9841 catttatatg aggttaaact gactgcaagt tactaaaaag aatgtattta cgaaataatc
     9901 gtaatctgtt ttagatagat taacgaaaaa gcccctccaa aaatgaaggg gctctaaaat
     9961 agttcagaat tcaagccgga taacggaatg aataaatgta ttacattaag aatcccagca
    10021 ggatacctgc tgctacagcg gaaccgatta caccggcaac gttcgggccc atggcatgca
    10081 tcagcagata gttggtagga tcgtattcca gacctactac ttgggagata cgtgcagagt
    10141 cgggtacggc agatacaccg gcattaccga tcaacggatt aatcttgttg cccttcttca
    10201 ggaagaggtt gaaaatcttc acgaagatga cgccggatgc tgtggcaatg acaaatgata
    10261 aggcgcccag accgaatatc ttgattgaat caagggttaa gaactcggat gcttgcgtag
    10321 aagcacctac tgtcaaacca agcagaatag taatggtatc aatcagcgga ccactggctg
    10381 tgtttgccag acgacgtgta actccacttt ctttcagtaa attaccgaag aacagcatac
    10441 ccagcaaagg cagaccggat ggtacaagga atgtggtcag taacaaaccg ataatcggga
    10501 acattacttt ttccgtatgt gaaaccacac ggggaggttt catacggata agacgttcat
    10561 ttttactggt cagccaacgc ataataggcg gctgtatcac cggtactaat gccatatatg
    10621 aataggctga taccgcaatg gcacccatta agttaggagc cagtttggaa gagaggaaga
    10681 tggcagtcgg accatcggca ccaccaatga taccgattgc accagcctgc atcgggtcaa
    10741 atcctatggc aagggcaatc atataagcac cgaatatacc gaattgggct gctgcaccaa
    10801 ccaacattaa tttggggttc gagatcaaag cggagaaatc agtcatggca ccgataccca
    10861 ggaatatgag tggcgggtac caaccggagg ttactccctg gtacagaata ttaagtacag
    10921 aaccttcttc atagataccg actttcaatc cggcttccat attgaaaggt atattaccaa
    10981 tcagcatacc gaaaccgata ggaattaata gcatcggctc aaattccttg gctacagcca
    11041 agtatatgaa aaacaaacct accagaagca ttaccacatg tcctaccgtt gcattggcaa
    11101 aacctgtata agtccagaag tcggcaaggt tgtttcctaa aaatgtgata aattctccca
    11161 tattattcaa taattacgag gtcagtacct tcgagaacag agtccccttt gtttacattg
    11221 atggctgtaa tcttaccgtc tttatcagca ttgatattgt tttccatctt catggcttcc
    11281 aaaatgatga taacttgtcc cttctttact gtatcgccga catttacttt gatatcgagg
    11341 attacaccgg gaagcggaga ttttacacct gacttgccgg tagaagcagc ggccggtttt
    11401 actaccggag tagcaggagc agcaggagcg gatgtggctg ccggacgtgc taccggttta
    11461 acaactacct tcggtgcttt ttccatttca actttgtagg gagtaccgtt cacttctaca
    11521 tgagcgatgt tgtcttcaat atctccaatg gcaactttat atacgttacc gttaatttta
    11581 tatttatatt ctttcatcgt tttattttat tatgggtgac ttactttttg tgaggagtct
    11641 cacgcaacgt ataaatcttt gaactccacg gtgagtaact gcgttttaca cgggtaatgg
    11701 taagtatcgt gtcttccaca tcgtgtacat cgctttggaa ttcgtgcatg gccattgaaa
    11761 tggcagcaaa aacttctccc ggagcctgcc ccagttgttt ctcttttgct tcttgtttat
    11821 cagtaatacc tttagctttc atggcattgc gtttgctgag gttaactgat attttaccta
    11881 taatcttgaa ggagatgtag agtaatatca gcccgcagaa tacaacgctc atggcagaaa
    11941 tagccatacc gatacctacg ctgtcatgct cttcgaattt ttccattttg gcattgctgt
    12001 cgatagtctt gttgttggta ctcggagtga catatttatc ttcgcttcca ccctttactt
    12061 cccattggtc ggctgcatca ctgacacggg cataggattg gttggctttt aaagtaccgg
    12121 caggcactat gacttgatca agcaatttct tgccggaatc atacaaccca atccagttgg
    12181 catttgtggc atccagtttg aagttcgtat gaaatgtacc gcgtcttggt tctccatcag
    12241 cccagaaaag tgcatgctga cgtggtttta tgagtgtcag aacgtcacct ttgggaatga
    12301 aataactggc agtatcaccc ggctggctgc tgaatttcag atagcaacct gcaaggtcgg
    12361 cgctgccgta tgatctgttg aatatttcaa tccatgcgct gtgcacaccg tagtcatcct
    12421 gatagttgct ctcgttgttg accagcactt cattcagcag cagtttgttg ttcgatttct
    12481 gttctttgca agaagagcaa aagcccaaca ccagcatcaa tgaaaggaat attccgattt
    12541 ttgttttatt cataatcgtt cttgttttag tgtgaaaagc ttgattacaa gggaatatta
    12601 ccatgcttct tagccgggtt agtcaatttc ttggtttgca actgttgcag ggcacgaatg
    12661 atgcggaaac gtgtgttacg cggttcgata acatcatcaa tgtagccata tttagctgca
    12721 ttataaggat tggcaaacaa cttggtgtat tcagcctctt tttcagccag gaattgagcc
    12781 ggattttcct gctctttggc ttcgcgggca tataatactt ctacagcacc tgcaccaccc
    12841 attacagcga tttcagcagt aggccaagca taattcatgt cgccacgcag ctgcttacag
    12901 ctcatcacga tgtgcgaacc accgtaggat ttacgcagtg tgatggtaac cttgggtaca
    12961 gtagcttcac cgtatgcata cagcagtttg gcaccgtgca ggatgacgcc gttgtactcc
    13021 tggccggttc ccggaaggaa tcccggtacg tctaccaatg atacgatagg aatattgaag
    13081 gcgtcgcaga aacggacgaa gcgtgcgccc ttgcgggatg cgttgctgtc gagcacacct
    13141 gccagatact tcggctggtt ggcaacaata cctacggact gtccgttgaa acgtgcgaaa
    13201 ccaataatga tattctttga ataatctttt tggatttcga ggaactcacc attatctatg
    13261 atagcaccaa ttacctcgta catatcgtac ggcttgttcg ggttatcagg aatgatgtcg
    13321 ttcagggaat cttccagacg gtcgataggg tctgtacagt ctacataggg agcttcttcc
    13381 aggttgttct ggggaatgta gctcaacagt ttgcggataa gagccaaacc ttcttcttct
    13441 gtctgtgcag taaaatgagt aacaccagat ttggtggagt gaacgctcgc accacccagg
    13501 ttttcctggc ttacgtcttc tccggttaca gtctttacta ccttcggacc ggtaaggaac
    13561 atgtaggatg taccttccat catcaaagta aagtctgtca aggcaggaga gtaaacggcg
    13621 ccaccggcac aaggaccgaa aataccggaa atctgcggaa tgacacccga agcaagtatg
    13681 ttacgttgga agatttcagc gtagccagcc aaggcattaa taccttcctg aatacgtgca
    13741 ccgcccgagt cgttgatacc gatacacgga gcacccattt tcatggcttg gtccataatc
    13801 ttacagattt tcagagacat ggtttcggac agtgaaccgg cagaaactgt gaagtcctgt
    13861 gcgaagatat aaaccagacg gccttcgatt gtaccgcaac cggttactac accgtcaccg
    13921 gggtagtgtt tcttttccat gccgaagttg gtgcatctat gttctacgaa catgtccatt
    13981 tcttcgaaac tgccttcgtc gagaagcatg gctatgcgct cgcgagctgt atatttaccc
    14041 ttctcgtgtt gctttgcaat cgctttttca ccaccaccga gacgtgctgc agcgcggcgg
    14101 tctataagct ctttaatctt ttcaagttga ttactcatga atttatattc tttaagtgtt
    14161 tatacaattt atgatttgat gattttacag tcttgcttat tccggtttct cgcaaagctc
    14221 ggtcaggaca ccgagagttg acttcggatg caggaatgca atgttcagac cttctgcacc
    14281 tttgcgggga gctttgtcta taaggcggat accttttcct tcgacttcgg caagcgcacc
    14341 ggccactccg tcttcaacgg cgaatgcgag atgatgcatg ccaccgttac cgttgttctt
    14401 ttcgatgaac ttggcaattg tgctttcggg agaagtaggt tccaacaatt cgatctttac
    14461 atcgcccact ttcaggaaag cggttctaac tttctgatct tccacggttt cgatgttgta
    14521 gcatttcaaa cctaaaacgt tttcgtagta cggaagggct tcttcaatgc tcttaacggc
    14581 aatgcccaga tgctcaatgt gtgaaatctt cataactata taaattaatg ttagtattgt
    14641 atccttttta ataaaggtat aaagcagcac aaagaaagag aattcttcct taataaagaa
    14701 atttttcatc aattaattaa tggttaattg aactttagaa ggattttttc agactttaga
    14761 tagagaccgg ttgttttctt gatatcgtcc gctaacggac atccccactg tccgaaaatg
    14821 aacacttacc cctctatgaa acctttccgg ccacttggca cactctttgc ttttctgttt
    14881 gcgacaattt taaagattga acatgaaaaa gaatatttta cttgcagttt gttttttgat
    14941 gccgttggca accatggcgc agaatgatac tttgggacat gaacgcaata ttacgctgtc
    15001 ggaggccatt gtactggccc gtacgcagtc tgtggatgct gctgtggcat tgaatgaatt
    15061 gaaaaccgcg tattgggaat accgtacatt ccgtgcggac ttgttgccgg aagtgaattt
    15121 caccggtaca ctacccaact ataacaagtc ctacagtacc taccagaatt ccgacggctc
    15181 ctatagcttt gttcgcaaca atacactggg gctgtccgga cagctttcgg tagaccagaa
    15241 catttggttt acggggggta agctgtcact gacttcttcg ctggattatc tcaaacaact
    15301 gggttccgga ggagcgaagc agttcatgtc agtccccgtg agtctggagt tgacgcaacc
    15361 ggtcttatcc gagaatgatt tgttgcagct taaactgaat tcattgcagg gcaaggccga
    15421 cgtgactgag gcagagagca acctgaatgc aaaaatgttc cagctccgtt ctttcctcgg
    15481 ggtgtccgag caggaaagcc tgaatccggt gttgcccgcc actgttcccg atataaagat
    15541 ggagtatgac cgtgtgctga acaaggcact ggaacgcaac tcctttgcac agaacattcg
    15601 ccgccgccag ctcgaagctg attatgaagt ggcaacggca cgcggaaact tgcgcagcat
    15661 cgacctcttt gccagtgtgg gctatacggg gcagaaccat gaattctctt cagcctaccg
    15721 ggacttgctt gataatcaga ttgtgcaggt aggcgtcaag attcctatcc ttgactgggg
    15781 caagcgccgc ggcaaggtaa gggtggcaaa gagcaaccgt gaagtggtct tgtccagaat
    15841 ccgtcaggaa cagatggact ttaaccagga catctttttg ctggtggcta acttcaacaa
    15901 ccaggcgcaa cagctggaca tagccgaaga ggcggatgtc attgctgaga agcgttacaa
    15961 gaccagtgta gagaccttta tgataggtaa aatcagcacc ctggacctga acgatgcaca
    16021 gaactctaaa gacgaagccc gtcaaaagca tatttcagag ctgtactact attggtatta
    16081 cttctatcag ctccgcagct tgaccctttg ggattttgaa cgcgatacgg aattggaagc
    16141 tgattttgaa gaggtggtaa gaggataagt cgacgggttg caagtgataa gttatgaatt
    16201 atttgccggt aaaagtaccg tatatgcgat attataggtg aataacttat aacttatcat
    16261 tcataactct gcttttttac ttatttttgc gggaaacaaa ctacaatttt tatgatactg
    16321 ataatagacg acgatagtgc tgtgcgctct tccctcagct ttatgctgaa gcgtgccgga
    16381 tatgaggtga aaacggctcc aagtcctcgc gaagctatgg acatagttag ggccgaagct
    16441 cccgccttga ttttgatgga tatgaacttc actctttcca ctaccggaga agagggactt
    16501 accttattga agcaggtaaa ggtgttccgt cccgatgtgc ccgttatttt gatgacggca
    16561 tggggaagta tccagcttgc cgtgcagggt atgcaggccg gcgcattcga tttcataacc
    16621 aagccttgga acaatgctgc tcttttgcag cgcatcgaga cggcccttga gcttacggcc
    16681 gccccgaaag aggtgccgga agagcagact accgcattga atcgcagcca tattataggt
    16741 aagtccaaag ggctgatgga agtgctgaac acagtggctc gcatagcccg taccaatgct
    16801 tcggtgctga ttacgggcga aagcggaacg ggcaaggagc tgattgccga agccatccat
    16861 atcaacagcc aacgcgtgaa gcagcccttt gtcaaggtga accttggtgg catctcgcag
    16921 agcttgttcg agagcgagat gttcggccat aagaaagggg cgtttaccga tgccagcgcc
    16981 gaccgtatag ggcgttttga aatggcaaat aaaggtacta tcttcctcga cgagattggt
    17041 gacctcgacc cttcctgcca ggtgaaactg ctgcgcgtgc ttcaagacca gacattcgaa
    17101 gtgctgggcg atagccgtcc ccgcaaagtc gatgtacgcg ttgtgtccgc cactaatgca
    17161 gacctccgca agatggtgtc cgaacgtact ttccgtgaag acctttttta ccgtatcaac
    17221 ctgattaccg taaaactgcc ctccttgcgg gagcgccgtg aagatattcc tttgctggca
    17281 cgtcactttg ccgaccgtca ggcagaggtg aacggcttgc cgcgtacgga tttctcggcc
    17341 gacgctctga atttcctttc ccgcctgcct tatccgggca acattcgtga gttgaagaat
    17401 ctggtggagc gtaccattct ggtcagcggc aagccggtgc tggatgccac ggatttcgat
    17461 gcccaatatc tgcgtcacga cgaaccggcc aaagctgccg aaggtacttc ttttgcaggt
    17521 atgaccttgg atgaaataga gcggcagact atcttgcagg cgttggaaca gcataaaggg
    17581 aatctcagtc aagtggcagt gtcattaggc atcagccgcg ctgcgcttta cagacgtttg
    17641 gaaaaatata atattcaagt cccgtgcgca taaaattctt tttcttcata ctcgtccttt
    17701 ttctgctcgg tctgggtgga atgctggtat atctgctgag tggaaagcct tctttgtatc
    17761 tgtacgtatt ggaggggctc atcgggttta tccttatcta tctgatagta ttctataata
    17821 agatagtgaa gccgatgaac accataggca gcggtatgga gttgctgcgc gagcaggatt
    17881 tcagtagtcg tctcagccgg gtagggcagt acgaggcaga ccgcattgtg aatatcttta
    17941 accgaatgat ggagcagctc aagaatgaac ggttgcgcat gcgcgagcag aatcacttct
    18001 tggatttgtt gattcaggca tctccaatgg gggttattat cctgacaatg gacgatgaag
    18061 tgtcgcaact gaatccgatg gcggtaaaga tgctcggtgt ccgtatggag gaggcgatga
    18121 caaaacggct ggaccagatg gactccccgt tggctgccga actttcgtct attcccaaag
    18181 acgagacggc ggtggtccgt ctcaatgatg cgaatattta taaatgcacc cattcttctt
    18241 ttattgacag agggttcaaa catccttttt tcttgataga gcgtatgacg gaagaagtga
    18301 tgcgtgccga gaagcgtgcc tatgaaaagg taatccgcat gatagctcat gaagtgaaca
    18361 ataccactgc gggcatcact tccacactcg atacagtgga gcaggcactt tctacagaag
    18421 atgatatgga ggacatctgc gacgtgatgc gcgtctgtac ggagcgttgt ttctcgatga
    18481 gccgtttcat tacccgtttt gcagatgtgg taaagatacc tgaacctacc ctggcacccg
    18541 tccaactgaa tgagttggtg tccatgtgca agcgtttcat ggaaggaatg tgcaatgacc
    18601 gcaatataga gctacgtctg gaatgcgacc cggaggtggg aatggtgcgt atggatgctt
    18661 ctctttttga gcaggtgctt gtgaatatca tcaagaatgc cgccgaaagt atagaggggg
    18721 acgccggaga aaacggacag caaggtgaga taatagtaag gaccactgcc cccgcttctg
    18781 tcgaagtcgt tgacaatggt ccggggataa gtaaagagac cgaagctaaa ctcttcagcc
    18841 ccttcttttc caccaagccg aacgggcagg gaattggcct ggtgtttatc cgggaagttt
    18901 tgagccgtca tggttgcacg ttctccctgc gtacctacag cgatggattg acccgcttcc
    18961 gtatactatt taattaaaat ttgaaagttt tacctttcac ctttcaattt tcaattttta
    19021 cctttcgcct ttccattttt aaagaattct tttgcatact cctccagtat ctttttgatg
    19081 ccttggccga tggttgcata gtctttctcg tccagattgg cgagtgaggc gcgtacgctc
    19141 cattcggggc cgtcaaaacc accgccgttc agcagcacca gagaggtttc tttggcaagg
    19201 cggaagacta cgttcagcgg gctgtaggta cgtttcagat attctacaaa gtcgtcccca
    19261 tagaacttct ttgcccaaac cagcatgtcg atttctgtat aataacctac gcgcaacggg
    19321 tcttccgtca gcgtgaaacc ggtattctcc caaagggcat gcaatcggcg gcggataatc
    19381 tcctgcatct tttgcttgta tttgttttcc ttgtccagca gggcaaaggc ggcgaaaagg
    19441 cccatctgca tctgttgtgg caatgacagt ccggcggtat ggttcagtgc cacctgacgg
    19501 ctgtcggcaa ccatacggtc gataaacttc agtttttcag gttccagagt gagggtggag
    19561 tagcggtggt gcagaatctc ccgtttctct ttcggcagtt tggctatcag cttgtcgaac
    19621 aggttgaatt cgtgcagggc aatgaccgca ttgcgccatc cggtggcacc gaagtatttg
    19681 gagaatgaat agacgcaaag cgtattgtag ggaatttctg ccatgaacga acggaagtgt
    19741 ggactgaatg taccgtatac gtcgtctgta ataatcatca gattagggtt gtcattcctg
    19801 acgatgctca cgatgcgcgc cattgtatcc ggactgagtg tgtagctggg cggattactg
    19861 ggattggtga caaagagggc cttgatttta gggcttttca agcggtctat gtcttcgtcg
    19921 ctgtactgcc agaggtgcat cccttcgtta ttcatgcggt tggcatgtat tttggtcact
    19981 cgaa
//
