LOCUS       c00153_gnlPro..         5612 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NLOPLDIL_153.
ACCESSION   c00153_gnlPro..
VERSION     c00153_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 16:07:05
            Original ID  :: gnl|Prokka|NLOPLDIL_153
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5612
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..747
                     /locus_tag="ctg153_1"
                     /transl_table=11
                     /translation="KADRVVLAGDHCQLPPTIKCHEAARGGLERTLMEKVVSNKPAVVS
                     LLKVQYRMHEEIMKFPSQWFYNGELEAASEVRYRGILDWDTPIHWIDTSEMDFKEEFVG
                     ETFGRINKAEADLLLSELKIYINRIGGSRILEEKIDFGIISPYKAQVQYLRNKIKADAS
                     LKPYRSLFTVNTVDGFQGQERDVIFISLVRANEEGQIGFLNDLRRMNVAITRARMKLVI
                     LGEAETLKHHGFYRKLLEFIQNIGNQ"
     protocluster    1..5612
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[808:5611]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      809..5611
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5612
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5612
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(809..1852)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg153_2"
                     /sec_met_domain="IlvN (E-value: 2.4e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.1e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIVMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(1903..2655)
                     /locus_tag="ctg153_3"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             complement(2652..3212)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg153_4"
                     /sec_met_domain="ALS_ss_C (E-value: 3.6e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(3245..4996)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg153_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.1e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRQAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNGAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(5081..5611)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg153_6"
                     /sec_met_domain="ILVD_EDD (E-value: 1.7e-74, bitscore:
                     239.9, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDAACDGILGGKVV
                     SGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGLSIGHVSP
                     EAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNREVSKALKAYACM
                     VSSADKGAVRLID"
ORIGIN
        1 aaagcagacc gcgtggtatt ggcgggtgac cactgccaac ttccgcccac cataaaatgc
       61 cacgaagccg cccgtggagg tctggaacga acattgatgg agaaagtggt gtccaacaaa
      121 cctgccgttg tctctttgct gaaagtgcaa taccgcatgc acgaggaaat catgaaattt
      181 ccttcccaat ggttttataa tggcgagttg gaagccgctt ccgaagtgcg ttaccggggc
      241 atcctggact gggatacccc tatccactgg attgacacct ccgaaatgga tttcaaagaa
      301 gaatttgtgg gagagacttt cggacgcatt aataaggcgg aagcggacct gctcctatca
      361 gaactgaaaa tctacatcaa ccgtatcggt ggcagccgca ttctggaaga aaaaatagac
      421 ttcggcatca tctcccctta caaggcacaa gtgcaatatc tccgcaacaa gataaaggca
      481 gacgcttcac tcaagcctta tcgcagcttg ttcactgtaa atacggtgga tggcttccaa
      541 gggcaagagc gcgatgttat cttcatcagc cttgtccgtg ccaacgaaga aggacagata
      601 ggattcctga atgatttaag gagaatgaat gtagccatca cccgggcacg tatgaagctg
      661 gtgatattgg gagaggcaga gacgctgaaa catcacggtt tttaccggaa gctattggag
      721 tttattcaaa atatagggaa tcaataataa agaaataccc cctccggtaa caccgaagag
      781 ggtatttcac ctatttatat aaagctgatt aattgttttc cggacgaagt ttacgaactg
      841 taacagctgt ctgccacatt tcgctttcac gcaaggcttt caattctgca ttcagcttct
      901 cacgataatc gggtttggag ttactgtcga tagaaatctg ggcttcgttg cccgacttca
      961 cacttgcata caatttctgt acaaccggct tgatggcatc atggaacggg gtcatccaat
     1021 ccagcgcacc acgctgtgcc gtagtagaac agttggcata catccagtcc ataccgttct
     1081 tggcaaacaa tggcatcaaa gattgagtca actcttccac tgtttcattg aatgcttcag
     1141 aaggagtatg gccgttttcg cgcaatactt catactgagc caacagtaat ccctggatag
     1201 cacccatcaa tgaaccgcgt tcaccggtca agtcggaagt ggcttcgcgg atgaaagttg
     1261 tctcgaacaa atatcccgaa ccgataccga tacccagtgc aatcgtcttg tcaaaagcct
     1321 tacccgtagc atcttgatag acggcatatg atgagttcaa gccacgccct tcgaggaaca
     1381 tggtacgaag tgaagtaccg gaacctttgg gagcaaccat aataacatca atatctttag
     1441 gaggaaccac gccggtacgg tcgttccagg taatagcaaa accatgagag aagtaaagag
     1501 ccttcccggg agtcaaataa ggtttgatag tcggccatac agacattaca gctgcgtcag
     1561 acaacagaca catgacgata gtacctttct gacaagcctc ttcgatgccg aacaaagtct
     1621 cacccggtac ccatccgtca gccacagcct tttcgtatgt cttacccgga cgttgtccta
     1681 caatcacatt gaaaccgtta tcacgcaagt tgcaagcctg gcccgggcct tgtacgccat
     1741 aaccgattac tgcaattgtt tcatctttca aaatctcacg tgctttttcc aaaggaaatt
     1801 cttcgcgggt cattacattc tcaataacac cgccaaaatt caattgtgcc attttttgtt
     1861 ttaattttta tttgtggctt acgccaacgt tgataaattt atttatttct ctgtaaatat
     1921 cactttagaa cgacagacca cttcgctgcc attctttttc acctccacat cgtaaacgcc
     1981 ctcaccggca tcatccatga acaaagtcaa ctcatcccca taatagcttt cggctacata
     2041 tgccatttca aaacgacgga tgcgcttctc cttatacatc tctatcggga acaaatcaag
     2101 gatatgctcg atgtaacgga tgctgttcac atgcccgtta atgtcaatat cactgtattt
     2161 ggctaccaaa gcagcaaccg gttcctttga ggccaccttt atccgcgaag gtttttctat
     2221 cgggcaaggc tcatcgcaaa cataatctac aatgctgcca ctatgaagag ccagcaaatc
     2281 tgccggctta cgggtattca tgctaatcat cgcccaaacg gaacgtgcat acccaatctt
     2341 cttaccctcc ttatcgatga tagcgaaatt acggtctgta aaaaggcgat agacattctc
     2401 cacccaagtc tgaatggaga aatcttcgta ctgataaggc atttcatcca gttcgacagc
     2461 cagacgggac aatacccaag tataattgtc ctcgtttaga gtcgcgatgc caaaaccgcg
     2521 gtcgctggca tggaaacccg cacaattcaa caaatggttg cccaatactc ccattgtcag
     2581 ccgtccggta aagtcgacat gaaacggttc ggcaacaaac ttgtaggtac ctatcttatt
     2641 gttctcgctc atcatgattc ctggtgttta ctttgacgat attttgcttc acggtccgcc
     2701 agatattcat tgacacgctc aaagcagctg gtcgtaatgg ctacgcgacc cgaacggacg
     2761 aactgaagta cgcaatccaa ctggcgcaac tcctcataaa gattggttat ttcctcactc
     2821 atgccattct tctcaacaat ggcaaataca gcattcacct ccacaatacg ggcattgtac
     2881 ttacggatta ctttggacac ctccggtttt tcttccagcg taggggtcgt tattttatag
     2941 agagcaatct cgtgctgata gatttcatca tccgtaaaat aatgggcttg cagcacatct
     3001 attttcttgg taatctgctt ggtcaccttt tcaatggtat ccttgtccgt ccaagcggta
     3061 atggtatatt tatgtacccc cttgatggag gaggccgata catttaaact ttcgatgttt
     3121 atctgccgac gggtaaacac agccgtcact tgattcagca aaccggcaaa gttttccgaa
     3181 tgaacaatga ttgtatatag ttttttatcc atagatagag taaattcttt aatttcgcat
     3241 gacttcagca ttccaacaac atctgattga ccgaaccgcc cggaggtgtc atcggcatta
     3301 catttccttc ttcctccaca caagcttcga gcaggaacgg tccgtcggtt gctatcatct
     3361 cgtcaatcgc ttttgccagc tcctcgcggg tcattaccct gcgtgcagga atatcatatg
     3421 ccgaagcaat cttcatataa tccggattca tcatcggagt aaacgaataa cgacgattga
     3481 aaaacatcgc ctgccattga cgaacattgc ccaagaagtt attgttcaac agaatcatct
     3541 tcaccggagc cttttgttcc atgatggtac ccagttcctg caggttcatc tgcaagccgc
     3601 cgtctcccat gaatacgcat accgtgcggt ccggacgtcc aaaagtggca ccgatagctg
     3661 ccggaaggcc gaagcccata gtacccaggc caccggaagt aacaatgcta cgttccttgc
     3721 tgtatttgaa ataacgggcg gacatcatct gattctggcc gacatcagtc accaatatcg
     3781 ccccgttatg ggtagcctca ctcacagcac gcaccacctc acccatgctt agcgcttttc
     3841 ctgccggatg taattccgga cggattacct tttcctcttc cacttcctcg tattgccgga
     3901 aactgtcaat ccattcctga tggttggcgg gttccagcaa ttgggtaacg gcagccagtg
     3961 tctctttgca atctcccagg acagcaacat cggtctttac attcttatct atttcggcag
     4021 ggtcaatatc aaagtggata atcttcgcct gcttggcata tgtttccaat ttacccgtca
     4081 cacggtcatc aaagcgcatg cctacggcga taaggacatc acatttattg gtattgatat
     4141 tgggccccag gttaccgtgc ataccaagca ttcctttgtt caacggatgg ttcgtaggta
     4201 atgcggaaag tcccaataaa gtgcatccgg caggcattcc ggctttctca atgaaagcac
     4261 gaagctcttg ctgggcttct cccagctcca cgccttgtcc taccagcacc aaaggccgtt
     4321 ccgcaccatt tattaattca gcagcctgcc gtatggcctc cggctccatt tcgggaacgg
     4381 gaagatagct acggacatag tccaccttag taggcgcata ttctgttttc tccacttggg
     4441 cgtttttagc aaaatccagc acgaccggtc ccggacgtcc gctctttgcc acatagaaag
     4501 cacgtgccac tgcccaggcc acatcttctg cacgacgaat ctggtaactc catttcgtga
     4561 taggctgagt aatgcctacc aagtccactt cttgaaatgc atccgtaccc aagaagttcg
     4621 tccctacctg gccggcaatg acaacgatag gcgtactgtc aatcatggca tctgcaatgc
     4681 ccgtgatagt attggtagca cccggtccac tggtaaccag acaaacgcca acctcgcctg
     4741 atacacgtgc aaagccttgt gccgcatggg ttgctccttg ttcatggcga accaagatgt
     4801 ggttcaattc cttccggtgg tcgtataagg catcgaatac cggcatgatg ctccctcccg
     4861 gataaccgaa aatagtcttt actccctgat gctccagaga gcgcatcaat gcttctgcgc
     4921 ctgttattag agcctcaccc cgaccctctc cttgggagag ggaggaaaag ttactctttt
     4981 tattattatc agccatactt tatcttttta ttaaaaactt cggaaatttg tatcattccc
     5041 tcctcccctc tctttcggag aggggtcggg ggtgaggcct ttaatcaatc agcctcacag
     5101 cccctttgtc agcggaactc accatacagg catatgcttt caatgctttg gagacttcac
     5161 ggttgcgggt taccggagtc atagggcgtg ctgcaagctc ttcatccgtc aacttcacat
     5221 tgatagaacg gttcggtata tcaatttcga taatgtcccc atccttaatc ttgccgatat
     5281 taccaccggc agccgcttcg ggagaaacat gtccgatgct tagtccggaa gtaccaccac
     5341 tgaaacgccc gtcggtaatc aatgcacact ccttacccag atggcgggat ttgatataag
     5401 aagtaggata aagcatctct tgcatacccg gtccaccttt cggcccttcg tgagtgatga
     5461 cgacgacgtc tccactgacc acctttccac ccagaatacc gtcgcaagcc gcatcttgtg
     5521 agtcgaagac tttcgccggc cccgtaaatt tccagatact ctcgtctaca ccggcagtct
     5581 tgacaacgca accgtcctga gctatatttc cc
//
