LOCUS       c00034_gnlPro..        15012 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AMLNIBKM_34.
ACCESSION   c00034_gnlPro..
VERSION     c00034_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:34:59
            Original ID  :: gnl|Prokka|AMLNIBKM_34
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15012
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15012
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1572:5012]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1573..5012
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15012
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15012
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(360..1313)
                     /locus_tag="ctg34_1"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPYETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPASGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             1573..2247
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_2"
                     /sec_met_domain="SucD_FumR (E-value: 1.2e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2286..4229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 3e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.9e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4257..5012
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_4"
                     /sec_met_domain="Fer2_3 (E-value: 1.2e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.6e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.8e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             5203..5361
                     /locus_tag="ctg34_5"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5334..6365)
                     /locus_tag="ctg34_6"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLNILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             6746..8005
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_7"
                     /sec_met_domain="Peptidase_U32 (E-value: 1.7e-68, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNN
                     FTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAM
                     NYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITG
                     PKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIEL
                     DIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNG
                     TFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDK
                     IGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEK
                     IRPSDRLYKMEKVQLEKVFE"
     CDS             8005..8412
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_8"
                     /sec_met_domain="HBT (E-value: 2.4e-08, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 3.7e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             8409..9524
                     /locus_tag="ctg34_9"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRIGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATSVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
     CDS             complement(9775..10665)
                     /locus_tag="ctg34_10"
                     /transl_table=11
                     /translation="MLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYFRY
                     APDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDETID
                     RTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDVPL
                     EVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPWKQ
                     VMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPDVI
                     ETDYPYLFQGLDLTK"
     CDS             11273..11635
                     /locus_tag="ctg34_11"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             11656..13392
                     /locus_tag="ctg34_12"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLPGISYLYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPV
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNQVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKVVNVKYTVPVTFRLSGGKKKT
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPSGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             13426..14979
                     /locus_tag="ctg34_13"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVADLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
ORIGIN
        1 acttctcttt tttcatcttt gttgactttt atgaagtcaa cctatttcag gacgagacaa
       61 tcgctcatct atctgtttta aatgaataaa ctccaagcat tttaaggtaa aagtagggag
      121 acaattttat caacaccccc atgtatccgc ccccgacacc cggatctata agagcgtaag
      181 atccgggtgt cgggggcgga tacatggggg tgttgggtaa gttttattac gtgtttttca
      241 ttgatttgta gctgtattta cataaaagag ccttgtcttt gatgatatag gagaacaagc
      301 cctttttcct tttcttgttt accttgccct gcaaattgtc agtttgtttt agtagaaatt
      361 caatcacgtt cgaaatcgga cagcacttct gccgtagtag cgttgatgtt cttgtccaat
      421 acataaatgc ggtaagacag gctcagttct ttaccgggtt ccaaggtgaa tgccttctgc
      481 ttggtcggtg agaaattcca catgacgtca ccggcaggct tgttgacagt tttgtcccat
      541 acgcgtaaag gctcaggata gttcaggttg gaaggggagg caacgattag gatacaggcc
      601 ttttcgtttc cggctttccc ttggtagtag caccaacggg ctctcgaacc gtcagcttcg
      661 tcgcgggaaa ggccttccga ggtgagcatt tcggctgtct gatcgttcca gtcttcgcgc
      721 gtacggatgc atatgccgcc ataacggtaa gcttccatgg tgatcgggct ggggctggcg
      781 aggcggatag tggtatgata gtcgatgtaa taacctggta aggatgttgt cccgatgttg
      841 atctccaggc gttcgttcat tgctactttt tctgcgggag aatcggggta gaccacatgg
      901 tccagtgtcg caacaaaacc gttgtcggat acgtgttcga agttgcggaa gcgaactgtt
      961 ccttgttttt tgtggagatt ccagaagtcg atctcgtttc cttcgaacgt ggttttcgtc
     1021 caggcatacc acaaaccgaa atgatggtaa tggtcggcgg gagaacaatt ggtcatcact
     1081 tcgcctccca atgtcttcaa aggatggatg aaaccgctgc gtttatagac cgagtcaacg
     1141 ccagaggctg ggtaaactgt ggtatagttg taagagaaca acagtttatc tcctatctta
     1201 tagtctaagg ttttccccgt gtcgacgacg gaacaggatg tttcgtaagg ctgacaagag
     1261 cctaagaaca gagaaatcaa aaaaacacca atagaaaaaa tagcagtttt cataatatga
     1321 caattaaata ataatcagtt atccggcaag accttgcctg tatcggctac aaaaaaacga
     1381 aattttttcg tttcgcacaa tccgtttgtg atatctgatg caaataaaac cagccagcaa
     1441 gcagcgttct aattgatgaa atatttcttt aatcgtttgc gtgatatggg gatttagcat
     1501 acctttgcac gataataacc atagattgga ggaaatttct aaatacaatt aaataactta
     1561 aattattatc ttatgtggtt acttaattct tctatcggga agaagctgat aatgagtata
     1621 tcaggtcttt ttctcattct gttcttggtg ttccacttat gtatgaacat tgcggcagta
     1681 ttttctggtg aagcgtataa cgtgatttgc ggtttgctgg gttctaactg gtatgctttg
     1741 ctcggtacat tggtgttggc tgcaggtgta gtcgtgcact tcgtgtatgc tattatcttg
     1801 actctgcaga atcgtaaggc tcgcggtaac gaccgttatg ccatcaacgc tcgtccgaaa
     1861 ggtgttgaat gggcttctca gaacatgttt gttttgggtg tgatcgttat cctgttcatg
     1921 gttctgcact ttactcagtt ctggtacaac atgatgtttg ccgaactggc aggtattcat
     1981 ggtgacattc atccgcagga tggtgcagcg tttatcaatt tctacttcca gggcaatgtc
     2041 gtgaatacgg tgttgtatct gatctggttc gttgctctgt ggtttcacct gactcacggt
     2101 ttctggtctg cgattcacac aattggctgg aacaataccg tttggttaag ccgttgggaa
     2161 tgtatctcta aatgggttgc cactattatt tgtggcttat tcgctgttat cacagttatc
     2221 ttctacctga acggtgtagg tgcttaattt cggatattat tttttcaatt tgaaaataaa
     2281 acattatgac tcaaatagat tctaaaattc ctcaaggccc gttggctgag aagtggacaa
     2341 attataaaaa tcaccagaaa ttggtgaatc ccgcaaacaa acgtcgtttg gacataattg
     2401 tagtaggtac tggtctggcg ggtgcttctg ctgctgcctc tctggctgaa atgggattca
     2461 atgtattgaa tttctgtatt caggactctc cccgtcgtgc acactctatc gctgcacagg
     2521 gcggtatcaa tgcggcaaag aattatcaga atgatggtga ctcggtttat cgtctgttct
     2581 acgatacaat caaaggtggt gactaccgtg cccgcgaagc aaacgtctat cgtctggctg
     2641 aagtgtcaaa ctctattatc gaccagtgcg tagcacaggg tgtaccattc gctcgcgaat
     2701 atggtggtct gttggataac cgttcattcg gtggtgctca ggtatcccgt acgttctatg
     2761 cccgtggtca gaccggacag cagctgctgt tgggtgctta ctctgcattg agccgtcaga
     2821 ttggtttggg aaaggtgaag atgtacacac gccatgaaat gctggatgtt gtgaaggttg
     2881 acggacgtgc tcgcggtatt attgcccgta atttgattac cggtaagatc gaacgttttg
     2941 ccgctcacgc agtcgttgtt gcgacaggtg gttatgtaaa tacattcttc ttgtctacta
     3001 acgcgatggc gtctaacggt tctgctgcat ggcagtgcta caagaaaggg gcttactttg
     3061 ctaatccttg tatggtgcag atccacccga cttgtgtgcc ggtgaaaggt gacttccagt
     3121 ctaaactgac tttgatgtct gaatcactgc gtaacgatgg tcgcatctgg gttccgaaga
     3181 agctggaaga tgcgaaggca ttgcaggccg gaacaaaaaa gggaaaggat attcctgaag
     3241 cagatcgcga ctactatctg gaacgtcgtt atccggcatt cggtaacttg gttcctcgtg
     3301 atgtggcttc acgtgccgct aaagaacgtt gtgatgccgg tttcggtgta aatagcacgg
     3361 gcttggctgt attcctggat ttctccgacg ctatcaaccg tctgggtaag gaagtggtta
     3421 aacagaaata tggtaacctg ttcgatatgt acgaagagat cacgaacgat gatccgtacg
     3481 aaactccgat gatgatttat cctgcattgc actactcaat gggtggtttg tgggtagact
     3541 atgaattgat gacttctatt ccggggctgt tcgcaattgg tgaagccaac ttctctgacc
     3601 atggcgctaa ccgtctgggt gcttctgctt tgatgcaggg attggctgat ggttactttg
     3661 tattgcctta cacgatccag aactatctgt ctgaccagat ccaggttccg cgctttagca
     3721 ctgacctgcc tgaatttgtg gaagcagaaa aggctattaa cgcccgtatc gcgaagttga
     3781 tgaacgtgaa gggtaaagaa actgtcgatt ctatccaccg taagctggga catatcatgt
     3841 gggaacacgt cggtatggca cgcgacgcgg aaggcttgaa agaagctatc caaatgttga
     3901 aagacctgaa gaaggaattc tggagcaatg tattcattcc gggtgaagcg aacagcttga
     3961 acgtggaatt ggacaaggca ttgcgtttgg ctgactttat cgaaatcggt gcattgatgg
     4021 cacacgatgc gttagaccgc gcagaatctt gtggtggcca cttccgtacg gaacatcaga
     4081 ccgaagaagg cgaagctatg cgtcatgacg ataagttcat gtacgtctct tgttgggaat
     4141 accagggtga agacaaagac ccggttatgc tgaaggaaga tttgaactat cagttcgttg
     4201 ttcctcaaac acgtaactac aagaagtaat aatcatcaat cacaaaaatt agaatcatgg
     4261 ataaagatat aaaggtaaca cttaaagttt ggcgtcagaa aggtccgaaa gataaaggac
     4321 agtttgagac ttaccaaatc gacaaaatca atcagagtgt ttctttcttg gaaatgttag
     4381 acattttgaa tgaacgtttg gttagcgaag gtaaagaacc tatcgtattc gaccacgact
     4441 gccgtgaagg tatctgcggt atgtgttcat tgtatgtaaa cggacatccg cacggaccgg
     4501 caacaggtgc aacaacctgt cagctctata tgcgccgttt caatgatggt gagacgatta
     4561 cgatcgagcc gtggcgttct gccggtttcc cggtaatccg cgacttgatg gtagaccgtt
     4621 atgcttatga taagattatc caggcaggtg gtttcgtttc tgtaaacaca ggtggggttc
     4681 ctgatgctaa tgcaattcct atttctaagg ctgatgcgga tttggctatg gatgctgctg
     4741 cttgtatcgg ctgcggtgct tgtgctgctg cttgtaagaa cggttcagct atgctgttcg
     4801 tctctgcaaa ggttagccag ctggctcttt tgcctcaggg taaggtggaa gctgctcgtc
     4861 gtgcaaaagc aatggttgct aagatggatg aactgggctt tggtaactgt acgaacactc
     4921 gcgcttgcga aatggaatgt ccgaagaaca tctccgttag caacatcgct cgcttgaacc
     4981 gcgagttcat ctctgctaag ttacaagact aatacattat atatatgtat atggaaaagc
     5041 ccgtcgtcaa tggcaacggg ctttctttat gttcgttcaa acccacaaaa aagccgcact
     5101 ccctataata aaagtggatg cggctttttt gttgctttcc agtgaaacag tctctcgatt
     5161 ccctctctgc aaagactttg ttaaccttag atctaaaata ctatgaaaaa aactcactgc
     5221 aaatataaag tatatttact gaatacgcaa gagtttgtaa ttacatttta ttgcaaattt
     5281 gctacttttt gttttaaaat tgacactgtg tgcggattca cactgttatt atatcaacaa
     5341 tcgatcgatt ctgacacttg agagtcgctt tgaaatccgt atcctgtatg aaatttgtcg
     5401 gggatggaat ccagaatgtc gaataatgct tccactgttt ccgcacgtag catggcgacg
     5461 cgtgtctgct tgaagtctgc aataccttta aacagcggag ttgcagccaa atggcggcga
     5521 atgtggagaa ttccccggcg ctcatccaaa cgttccacgc tttgttccac ctgctttttc
     5581 agtatgttca gataccatga aaaagattcg gcaggcaatg tctcgcctgt atccagataa
     5641 tgcctcactt ctctgaaaat ccaggggcgg cctatgctgc cccggccaat cataacggca
     5701 tccacgccat attgttcgaa acgttgtttg cagatttcgg cggaagtcac atcgccattg
     5761 ccgatgatgg gaatttgtat gcggggattg ttttttactt caccgatcag tgtccagtct
     5821 gcctctcctg tatacatctg tgcccgggta cgtccgtgga tggaaagggc tgcgataccg
     5881 caatcctgta gctgttcggc caagtctacg atgatccggt tgtcggcatc ccagcccaag
     5941 cgggttttta cggtgacagg gatgttcacc gctttgacga cttcacgggt gatgtccagc
     6001 atcagtggaa tattgcgcag catgccggcg cctgctcctt tgcctgccac tcgtttgaca
     6061 gggcaaccga aattgatatc gagaatgtcc ggatgagcgg cttcgcaaat ttgcgcggct
     6121 tcgaccattg tcggaacatc acggccatat atttgtatgg cgaccggacg ttcttcatcc
     6181 gccacattca gcttttgctg tgttttattt acactgcgga tcagggcgtc tgctgaaacg
     6241 aattcggtat aaaccatatc ggcaccaaaa cgtttgcaca tcaaccggaa agaaatatct
     6301 gtaacgtctt ccatcggagc taagaagacg gggcgttcgc ctaaatctat tgtacctatt
     6361 ttcatattta tattatcaat gacggggaca aaggtactga tttcctgcta aaaacaggga
     6421 taaaaggata tctactaaaa agtgtagtaa ttgatcaata gaaagtacaa atgtcatact
     6481 gtcaatgata tagataaaat gataagctga aatcatgata gttgcatgat agtagtatga
     6541 tagttaaaaa tagaaactat catgtcttaa ggtattgaat aacagattct aaaggacaac
     6601 aatgacagta tgatggttgt tttgcaaatc tttatagaaa atggtatttg atcacgattt
     6661 tgatgctctg agaaacggat acccatgcaa ttcttctcgg atattattcc tacctttgcg
     6721 aacgaaccag taaatgtata agaacttgaa cgagaaagat tttgaaataa tggcgcctgt
     6781 cggttcgtac gaatcactga tggcggctat ccaaggggga gccgattcta tctatttcgg
     6841 tatcgaagga ttgaatatgc gttcgcgctc ttccaataac tttacgacag acgatttgcg
     6901 caagatcgtt gcgctttgtc gtgagcacgg tattaagagc tatttgaccg tcaatacggt
     6961 tatttatggg gaagacctgc ctctgatgcg cgagattatc gatgcggcga aggaggcgga
     7021 agtttcagcg atcattgcgg ccgatgtggc agctatgaac tatgccaaca gcatcggaca
     7081 ggaggtgcat ctttccacac agctcaacat ttccaatgcg gaagcactga aattctatgc
     7141 ccgttttgcc gatgttgtcg tcttggcgcg tgagctgaat ttgaaacagg tgcatgaaat
     7201 ctatcggcag atcgtcgacc agcagattac gggaccgaaa ggagaactga tccgtatcga
     7261 aatgtttgcc cacggagctc tctgtatggc cgtttccggt aaatgttacc tgagcctgca
     7321 cgaaatgaac gcttccgcca accggggagc ttgcatgcag atttgtcggc gtgcttattc
     7381 ggtaaaagat aaagacagca atatcgaact ggatatcgaa aaccagtata ttatgtcgcc
     7441 taaagacctt aagacaattc atttcatgaa taagatgatg gatgcaggtg tacgggtatt
     7501 caagatcgaa ggacgtgccc gcggtcccga atatgtccgc ctggtgaccg aatgctataa
     7561 ggaagctgtg cgtgcttatt gcaatggcac gttcgatgaa aagaaagttg ccgcttggga
     7621 cgaacgcctg cgcagtgtgt tcaaccgagg attctgggac ggctattatt tggggcaacg
     7681 gttgggtgag tggagtagca aatatggctc cggcgcgact aagaagaaag tgtatgttgc
     7741 caaaggaatc aaatatttcg acaagatcgg cgtggcggag ttcgaaatgg aatccggtaa
     7801 cctgaaagtg ggtgatgaga tcctgattac cggaccgaca acgggtgcgg ttatgcagac
     7861 gatagaagaa atccgtgtgg acttgaagcc ggtggacgag accgttaaag gtgaacggtt
     7921 ctctctcaag gtgaacgaga agattcggcc gtctgaccga ttgtataaaa tggaaaaggt
     7981 tcaacttgaa aaggtatttg aataatgaaa gagtatattt ttaaactgac agacaaggtc
     8041 cgtgactacg aatgcgacct gcaaggagtg gtcaacaact ccaattatca gcattatatg
     8101 gaacatactc ggcatgaatt cttggagtcg cttggcgaga acttcggaaa gatgcacgaa
     8161 aaaggggttg acggatttgt atcgcgggta gaaatccagt ataagacctc gctcaagagc
     8221 ggcgacagct atatctcttg cctcaatgtc tataaaaaag gagtcaagct cgtattcgag
     8281 caggatatat atagggcttc tgacaatgca ttggcgacga aaggaatcgt cgagtcggtt
     8341 atcgttgaga acggaaagtt gacacgcggt gaatatttcg acgaaatgct aaaaagaata
     8401 gaacatacat gactgacaaa cggatttacc aaatcggcct tactatgata aacggcgtgg
     8461 gagatatcct ggcgcgtcat ctcctgcagg ctttgggaga agcagaggct gtgtttactg
     8521 aaaagcaaca gttgttagga aggatccctg gtatcggcag caatattgct gccgaaatca
     8581 aacgcccgga aatcttgcaa cgggcggaaa aagagttggc ttttatcgag aaaaacaata
     8641 tttcctgtta ttatctgact gatacagatt atccggtgcg cttgagagaa tgtccggatg
     8701 cccctatact tttctatttt aagggaaata ctaaccttga tgcgacccgt atcatcagta
     8761 ttgtgggtac tcgcaacgcg accgaatatg gtcgggagct taccgaatcc cttataaaag
     8821 acttggcaaa agtgatcccg gacttgttgg tcgtgagtgg attggcttac ggcatcgata
     8881 tctgtgccca ccggaacgct ttgtacaacc gacttccgac tgttgctgtg ctggcgcatg
     8941 gcttggatcg tatctatcct tcctgccatc ggaatacggc tgtcgaaatg ctggaatcgg
     9001 gcggtctgtt gaccgatttt cccagcggta cagaaccaga ccgtccaaat ttcctccgga
     9061 ggaaccggat tgtcgccgga atctcggatt gtacgatcgt ggttgaatcg gcagaaaaag
     9121 gaggctcttt ggtaactgcc gatattgcat tctcttatgg ccgggatgtc tatagctttc
     9181 cagggcgcat cggtgacagc cattccaaag gatgcaacaa tttgatccga caaaataaag
     9241 ccggcctgat cacttctgcg gacgatctgc tctccgctct ttgttgggat atccaagctg
     9301 gggctacttc cgttcaaacg gagttgtttt tcgccgaggc ggaaacattc acctcggaac
     9361 aaaatccggt tttagccatt atgcgaacgc ggaatgagat ccatatcaac gagcttgcct
     9421 cagtgttgga gataccggta catcaactct ctatgctatt gttcgaactg gaaataaacg
     9481 ggaaggtaaa agcgttgccg ggaaatctct ataagctgtc ctgaccggct ttttcgtata
     9541 cgatttgtat gtgggagaag aaacggaacc tctataaaca attaaaggct gtctcacgac
     9601 aacccctaac caactttgtt aaccttaaat ctaatactat tatgaaaaaa ccacattgca
     9661 aagatacact cgtcaagagc gtttgtcaag cattttgtcg ctaatacttg ttaatcagat
     9721 gagcataaat agcaaaaaga ttttaatcgg ctataaagag tcctttaaac tgcgttattt
     9781 tgttaaatcg agtccttgaa acaggtacgg atagtccgtt tcgatcacgt cgggacgagt
     9841 gctgatctct gaccggtaac cggcggtttt ctctgtttcc gttttcgcgc gatcatgtgt
     9901 cggagcaacg gaaatcatgc acatgactcc gttacggtgc agagcgtcat acagtggttg
     9961 ctgttcaggc ttcatcttcg ggcctacata agccattacc tgtttccagg ggatgccggc
    10021 tttttcataa ttatcgaatt cttcccgatt cttacaccag caagaaaaca tcgcatccgg
    10081 tttccggtcg agataatagc gggcttgact ggcgttatgt accgtgtaca tgacgttaac
    10141 aggcttttct gtttctataa aatcagccat aacttctaaa ggtacatcct tgatatccaa
    10201 attcaggatt gttttgcctt tgctccattc caggcattct tttaaagttg gaattttgaa
    10261 ggctgtcacg ttgccgtttc ggtccaccag attgaattgt tgcagttctg cataagtgta
    10321 atctgaaacc tttcctttcc cggtagttgt ccggtcgatg gtttcgtcgt gcatcaatac
    10381 gattatcccg tcttttgtca aacgcggatc tatctcgaaa aacgattcca tataggacaa
    10441 ggtcttttcg aatgattcga tgcagttctc cggatagccg tctagcattc caccacgatg
    10501 tccactgatt acaatcgggc gatcgggagc ataccggaaa taggcttgta gatcccggct
    10561 gttcttcaca gtaatgtaat gaggattttg ttctttgtct gaagccaaaa gattcccggc
    10621 aggcataaaa ccccctaaaa ggagtaccaa aataaaagat agcattttca tgatattgta
    10681 tttatataga ttctttgtca attatgcggc ttaaaagtaa gactttttta tcagtggcgt
    10741 actataaaag cactataaaa acatgaaaat atgacaggca acaagatgtg caaagaaaga
    10801 ggcaggtata taaaaaatta aggattgtca tctcgacaac ccctaaccaa ctttgttaac
    10861 cttaaatcta atactattat gaaaaaacca caatgcaaaa atacactagc taagcttgtt
    10921 tgtcaaacct tttacggata atatatgtta agctctaata gctattttgt caaaaaatgt
    10981 tggttattta taaactatac agattccatg taaaaactgc taattcaaat actttttatc
    11041 gtcggaaaaa gtgaaatccc atgcttaaaa agtgtcccct tggagtatat aaaatcatta
    11101 attaatatag gggatgcttt ggtgtggctg cttatagata aattcctttt tggcgcatgc
    11161 agcgaataga tgatagatta ttaattgtta atacaaatta acgcattatt tcttgcatat
    11221 ttacgatgta ttcgtagatt tgcgatacga tcgtaaaaaa taatatagaa acatggaaag
    11281 attaacaaga caggaagagg atgtaatgcg ctggatctgg cagatcgagc cgtgttttat
    11341 caaagacatc ctggcgaagt atgaagagcc taagcctcct tatacgacac tcgcttctat
    11401 tgtgaagaat ctggaacgta agaaatacgt gaaagcgaaa cgttacggaa atacttacga
    11461 atacaggccg ctgatcccac aggaggaata taaacggacg tttatgggaa gtgtggtgaa
    11521 caactatttc gagaactctt acaaggaaat ggtctccttt tttgctaaag aacagaagat
    11581 atcgaccgat gagttgaaag agattatcga tatgattgaa aaaggacgag aataaactgt
    11641 taaatacata atgccatgac accggaattt gcctacttct tgaaggtaaa tgtagctttt
    11701 atactccttt atgccttcta ccggctgttc ttttataagg acaccttctt taaactacgc
    11761 cgtaccatct tgttggcatt tttcggggtg tcattgcttt atccgctgat gaatattcag
    11821 gattggatcc gggagcaggg gccgatagtg gaagtcatac aaatgtattc agccattttg
    11881 cccgaaacga caataacccc cggcaatgtt ccccaaacaa attggcatga tttgttactt
    11941 cccggtattt cttatcttta ttggagcggt gtaattgcct tatcgttccg ttttttagtg
    12001 cagttgagca gcatcttgtt actggcacgg cggtcggaag tgactttgat ccgtaacgta
    12061 cgtgtacatc tgttgaataa accggccggt cctttttctt ttttccggct ggtatttctg
    12121 catcccgaca gccattccga gaaagagatc gatgagattt tggtacacga gtgtacgcat
    12181 gtcagccagt ggcattcgat tgacgtgatt atttgcgaat tggtttgtat catctgttgg
    12241 gtgaatccgt ttgtctggct gttgaaaaga gaggtacgtc ataatctgga atatttggcg
    12301 gatgatacgg tacttgaatc gggctatgac agtcgtagct accaatatca ccttttgggg
    12361 ttggcacata ccaatagatc ggtgacctct ttatctaata actttaatat gctgcatctg
    12421 aaaaatcgga tcagcatgat gaataagaaa cgttcccgga gcataggtag gacgaaatac
    12481 ttgattttta taccggttgt gggcgccttg ctgattttaa gcaatgtcga tgcattggcc
    12541 cggatcacgg acgaactgac ggaaagcacg tttgccgatg tcttgctacc ggaggctatc
    12601 ttgccgttcc cttttgtcgg tgatgcttct cctgctgaaa aacgtgagga gtatgtgcta
    12661 tcggaggaag gaattgaggc tgccagacgt gcccgtaacc aggtgtttac cgttgtggag
    12721 gtaatgccgg aattccctgg cggacagggt gctctgctga aattcctggc gacgaatgtc
    12781 agatacccgg aatcggccgt taaaaatggt atagagggac gggttagctg ttctttcgtt
    12841 gttggaaaag acggggctat ctcggaggca gaagtgattc gtggggtaag tccggaactg
    12901 aatgaggagg ctttgcgtgt gataaactcc atgccggtat ggtcgccggg gaaacagcgg
    12961 ggcaaagtgg ttaatgtcaa atatacggta ccggtaactt tccggctttc cggtggaaag
    13021 aaaaaaacat cctctcgtat cgtgcagagg cagattaaag aagtcgatac gtccggtcgt
    13081 gtctttacgg tagtgcaaca gatgccggaa tttccgagtg gacaggcttc gttgttgaaa
    13141 tatctggcaa cacgcataaa atatccggct attgctcagg agaatggaat acaaggacgt
    13201 gtctcttgct ctttcgttgt cgacacggat ggaagtttga aaaatattga agtgatccgt
    13261 ggaatcgatc cttcgctgga cagggaggct gtccgagtga tccgggaaat gccgaaatgg
    13321 aatcctggcg tacaaaacaa tatggctgta gccgtaaaat atacggttcc ggttactttc
    13381 cgtttgcagt aattgaccag aatcggtcat taatacgata ccattatgaa atgtaagttt
    13441 tctctattac tgtttctttg cgtactgtcc ctttggggac aggcgcagag tcttaatctt
    13501 caggaattgg tcaataaaaa acaatttcag gaagttgtag cacgtgcgga tagtcttact
    13561 cctgccgatt cagccgatta tgctacaatg tcggcaatcg ggcaggcgta tgagggactg
    13621 ttgcgctata aggaggccta tcagtgtttt tctcattgct tgaagatgga tacgaacaat
    13681 gtggatgcat tgaacgccgt tgccaggaat gcgatcaatt tcggaaggat agcggaagct
    13741 aaacaatgtt atcgtaaagt attgggaacc gacagcatga acttctatgc caactatcag
    13801 ttggcgcgtc tctattatca gttgggagat tatggtcgag cgacggaaca ctatcatata
    13861 cttgcttcca tcgaaggtga aaatccttct atcctgaccg ggctggctga ttgccatatt
    13921 aaaagaggga ccggtcctaa tacgatgatc gctctttctt tgtatgcccg tgctttggag
    13981 ctgaacccgg aaaatgtacg tgtggcatct tctctgataa atacgttatt gcggatgggg
    14041 gacggacagg gagctttgca ggtgtgcgat accgccttgt tctataatcc ggataacagc
    14101 cagatacggc agagtaaagg gatggctctc tatatgacga aagattataa gcaggctgat
    14161 tcagtctata ccggtctatt ggccgatggc gattcttctt ttttgaatct taaatatgcg
    14221 ggggcggccc gctatatgtc cggtcatgca cttgatgggg tcgagctgct ggagaaggcc
    14281 tatgaaatag attcgacgga tgtggaaaca gtcatgttgt atggcgcttc cctgggaaaa
    14341 acatacgacc gtaaacgggc ttatgagctt ttcgatctgg cggaaacgaa tatgcagccg
    14401 aaaaaattcc tagttaatat gttgacgacc ttccgaggtg atgccttgga aagggacggc
    14461 cgttggcccg aagcggaaaa gctgtattat gccgcatgga aggaagaccc aacccagttg
    14521 cacttcctgt ataagatcag tacacaatac tgggatgtcg atccgggact ctttcagcag
    14581 gaggaaaaat tgcaaaagac gattttcagt agatacactt acctgacagc ctatatgaag
    14641 acagacaagt cgcaaaagta tctttataat taccgccctt tcttggaagc ggtttgtgaa
    14701 gatgcctttt tccggaatgc cgatgaagtg acgatgttgg ctcccgatgg gaagaagacg
    14761 aagttggctg tcgctgatct gcgtgccttg gtcgcccaac tgccgcagat gccggaagat
    14821 gaacgtttga ggcgcgagaa gatgcaggaa catattaaaa aagccagaga aaaagaaaag
    14881 gaattgcgta aaagcggtgc taaactcgat acgctcgccc tgagtaagga agaaaaagag
    14941 aaagcacgga aaatgttgaa agacgccgac ttggaataga tagaatatct gaacaatata
    15001 atcgatataa at
//
